Uma erupção na pele que surge de repente e se espalha pelo corpo todo, caracterizada por febre e várias bolinhas pequenas cheias de pus sobre uma área avermelhada.
Introdução
O que você precisa saber de cara
Uma erupção na pele que surge de repente e se espalha pelo corpo todo, caracterizada por febre e várias bolinhas pequenas cheias de pus sobre uma área avermelhada.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Entender a doença
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 6 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 23 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Pustulose exantemática generalizada aguda
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Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
Pesquisa e ensaios clínicos
3 ensaios clínicos encontrados.
Publicações mais relevantes
Acute Generalized Exanthematous Pustulosis in a Neonate Following Hepatitis B Vaccination: A Case Report.
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction in neonates and is most commonly drug-induced. Vaccine-associated cases are uncommon in this age group. We report a term male neonate who developed clusters of non-follicular pustules on erythematous plaques approximately 6 hours after receiving a birth dose of hepatitis B vaccine. The infant remained clinically stable, without fever or systemic involvement, and had no exposure to concomitant medications. The rapid onset following a single exposure, characteristic morphology, and prompt resolution were highly suggestive of AGEP. Laboratory investigations and skin biopsy were not performed due to rapid clinical improvement. Infectious etiologies and transient neonatal pustular dermatoses were considered less likely based on the clinical course. Patch testing with the same vaccine lot was positive, supporting a type IV hypersensitivity mechanism. The eruption resolved almost completely within 48 hours with topical hydrocortisone, without complications or recurrence.
The Hidden Perils of Allopurinol: A Systematic Review of Allopurinol-Induced DRESS (Drug Reaction With Eosinophilia and Systemic Symptoms) Syndrome.
Drug hypersensitivity reactions are a clinically significant and potentially preventable cause of hospital admission, treatment interruption, and drug-related mortality worldwide. Within severe cutaneous adverse reactions (SCARs), a group that includes Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS), DRESS stands out because of its delayed onset, multi-organ involvement, and frequent diagnostic uncertainty. Allopurinol is a commonly prescribed medication for hyperuricemia, but in rare cases, it can trigger DRESS. This systematic review was conducted to comprehensively summarize the demographic characteristics, clinical manifestations, diagnostic features, management strategies, and outcomes of reported cases of allopurinol-induced DRESS syndrome. Available case reports and case series were analyzed to consolidate patient characteristics, patterns of organ involvement, treatment approaches, and clinical outcomes. The findings indicate that allopurinol-induced DRESS most often presents with cutaneous manifestations and systemic involvement, most commonly affecting the liver and kidneys, and is associated with considerable morbidity and mortality despite treatment. These results emphasize the importance of early recognition, prompt drug discontinuation, and cautious prescribing of allopurinol, particularly in high-risk populations.
A Systematic Review of Pediatric Acute Generalized Exanthematous Pustulosis.
Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction in children. In this systematic review of 47 cases, a male predominance was observed, and medications remained the most common trigger for AGEP, with a higher contribution from infectious etiologies compared with frequencies reported in adult studies. Management primarily involved cessation of the inciting drug, topical corticosteroids, and supportive care. These findings provide practical guidance for early recognition and evaluation of pediatric AGEP.
Acute Generalized Exanthematous Pustulosis: An Integrated Study of 503 Cases with Emphasis on Drug Culprits, Clinical Features, Diagnosis and Treatment.
Acute generalized exanthematous pustulosis (AGEP) is a drug-induced severe cutaneous adverse reaction (SCAR) characterized by an acute extensive erythematous pustular eruption. Integrated analyses including Asian cohorts remain scarce. A total of 503 AGEP cases were analyzed by combining two distinct, routinely-collected data cohorts: (1) a literature-derived cohort (PubMed, Embase, Web of Science, and CNKI) and (2) a hospital-based clinical cohort from a tertiary-care center in China. The hospital cohort data were collected retrospectively from January 2015 to July 2025. Demographic, etiologic, clinical, laboratory and therapeutic characteristics were summarized. Drugs were stratified by median latency (3 days) into short- versus long-latency groups to explore class-specific patterns. Drugs triggered 94.6% of cases, mainly β-lactam antibiotics (20.7%), non-β-lactam antibiotics (16.3%), and hydroxychloroquine (10.4%). With a 3-day median latency threshold, antibiotic-related reactions showed short latency, whereas antimalarials, analgesics, and antifungals exhibited longer latency. Hospitalization occurred in 75.1%, and systemic involvement in 20.2% (mostly hepatic or renal). Mucosal lesions were infrequent (oral 8.7%, genital 1.8%). Among those tested, patch tests were positive in 71.6%. Systemic corticosteroids were the mainstay (63.8%) of treatment, with cyclosporine (3.7%) and intravenous immunoglobulin (2.5%) used as adjuncts. A few refractory cases received biologics, including IL-17 inhibitors (eg secukinumab, brodalumab) and IL-36 receptor blockade (spesolimab), achieving partial or complete response. Eight deaths (1.6%) were documented, mainly among older, comorbid, polymedicated patients. AGEP displays distinct drug class-specific latency signatures and occasional systemic morbidity. We propose a conceptual AGEP causality triage framework integrating latency and allergologic evidence to enhance culprit identification in polypharmacy settings. Given the mechanistic involvement of the IL-36-Th17/IL-17 axis, biologic agents targeting IL-17 or IL-36 pathways show promise in severe or corticosteroid-refractory AGEP, warranting confirmation in larger prospective studies.
Iodinated Contrast-Induced AGEP and ALEP: Recognition, Diagnosis, and Management.
Acute generalized exanthematous pustulosis (AGEP) and acute localized exanthematous pustulosis (ALEP) are rare T-cell-mediated hypersensitivity reactions most commonly triggered by medications but increasingly recognized after exposure to iodinated contrast media (ICM). With the growing use of contrast-enhanced imaging, clinicians are more frequently faced with diagnostic and management challenges in patients with suspected ICM-induced reactions and with decisions regarding future contrast exposure. This systematic review aimed to synthesize published cases of ICM-associated AGEP and ALEP, with a particular focus on clinical recognition, diagnostic evaluation in routine practice, acute management, and implications for future imaging. The review was registered in PROSPERO (CRD420251140990). Searches of PubMed/MEDLINE, Web of Science, and the Serbian Citation Index (SCIndeks) were conducted without language or date restrictions through September 9, 2025, supplemented by backward and forward citation searching. Thirty-one publications reporting 53 patients were included. Patient age ranged from 4 to 93 years (median 56 years), and most were female (64.1%). AGEP accounted for 96.2% of cases, while ALEP was rare (3.8%). AGEP was associated with iomeprol, iodixanol, iohexol, iopromide, ioversol, iopamidol, and iobitridol. ALEP was linked to iomeprol and ioversol. Onset was typically rapid, with a median of 1 day after ICM exposure. Recurrent reactions occurred in 18.9% of patients, often with shorter latency upon re-exposure. Reported management most frequently involved topical corticosteroids, systemic corticosteroids, and antihistamines. Nearly all patients (98.1%) recovered. Clinicians should recognize ICM as potential triggers of AGEP and ALEP and pursue appropriate diagnostic evaluation and allergological assessment to guide safe future imaging.
Publicações recentes
Concurrent Drug-induced Rowell Syndrome and Acute Generalized Exanthematous Pustulosis.
A 69-year-old man with acute generalized exanthematous pustulosis.
An Unusual Case of Drug-Induced Hypersensitivity Syndrome With Multiple Atypical Histopathologic Findings.
The Hidden Perils of Allopurinol: A Systematic Review of Allopurinol-Induced DRESS (Drug Reaction With Eosinophilia and Systemic Symptoms) Syndrome.
A Systematic Review of Pediatric Acute Generalized Exanthematous Pustulosis.
📚 EuropePMC702 artigos no totalmostrando 196
The Hidden Perils of Allopurinol: A Systematic Review of Allopurinol-Induced DRESS (Drug Reaction With Eosinophilia and Systemic Symptoms) Syndrome.
CureusA Systematic Review of Pediatric Acute Generalized Exanthematous Pustulosis.
Pediatric dermatologyAcute Generalized Exanthematous Pustulosis: An Integrated Study of 503 Cases with Emphasis on Drug Culprits, Clinical Features, Diagnosis and Treatment.
Journal of inflammation researchAcute Generalized Exanthematous Pustulosis in a Neonate Following Hepatitis B Vaccination: A Case Report.
Sage open pediatricsIodinated Contrast-Induced AGEP and ALEP: Recognition, Diagnosis, and Management.
International journal of dermatologyAzathioprine-induced acute generalized exanthematous pustulosis in a woman with autoimmune hepatitis.
Dermatology reportsCarbamazepine-induced acute generalized exanthematous pustulosis triggering diabetic ketoacidosis in a patient with type II diabetes mellitus: a case report.
Annals of medicine and surgery (2012)Semaglutide-Induced Atypical Pustular Drug Eruption: A Case Report.
CureusClinical differentiation between acute generalized exanthematous pustulosis and generalized pustular psoriasis: A multi-center study.
Chinese medical journalSerum neutrophil gelatinase-associated lipocalin as a potential signature for acute generalized exanthematous pustulosis and generalized pustular psoriasis: A case-control study.
JAAD internationalOptimizing the EuroSCAR criteria for acute generalized exanthematous pustulosis: A streamlined diagnostic model.
Journal of the American Academy of DermatologyA real-world pharmacovigilance study of FDA adverse event reporting system events for cefazolin.
MedicineA novel case of acute localized and generalized exanthematous pustulosis following IL-2 analogue injection amplified by immune checkpoint inhibition.
JAAD case reportsCase Report: Acute generalized exanthematous pustulosis with psoriasis successfully treated with Secukinumab.
Frontiers in immunologyCross-spectrum efficacy of spesolimab in IL-36-mediated dermatoses: a 'case study.
The Journal of dermatological treatmentAcute Generalized Exanthematous Pustulosis Mimicking Toxic Shock Syndrome in a Pediatric Patient.
Pediatric dermatologyHydroxychloroquine-Induced Acute Generalized Exanthematous Pustulosis.
The Journal of rheumatologyEtoricoxib and its hidden risks: a case-based review of dermatological, hematological, and cardiovascular complications.
EXCLI journalSkin-adverse drug reactions in the elderly: An underestimated and avoidable issue.
Annales de dermatologie et de venereologieAmpicillin-induced Acute Generalized Exanthematous Pustulosis in a Neonate: A Rare Cutaneous Adverse Reaction.
Acta dermato-venereologicaLetter: Propranolol-Induced Acute Generalized Exanthematous Pustulosis Confirmed by Patch Testing: A Case Report.
Dermatitis : contact, atopic, occupational, drugAcute Generalized Exanthematous Pustulosis Secondary to Application of Tapinarof Cream 1.
CutisRisk Factors for Drug-Induced Acute Generalized Exanthematous Pustulosis(AGEP) from 2004 to 2024: A Real-World Study Based on the FAERS.
Clinical, cosmetic and investigational dermatologyA real-world data analysis of piroxicam in the FDA Adverse Event Reporting System (FAERS) database.
Frontiers in medicineAcute Generalized Exanthematous Pustulosis Linked to Iodinated Contrast Agent Iomeprol.
Indian dermatology online journalACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS (AGEP) CAUSED BY ANTIBIOTIC POLYTHERAPY: A CASE REPORT.
Acta clinica CroaticaQuality of life in hospitalized patients with acute generalized exanthematous pustulosis: A prospective qualitative study.
Journal of the American Academy of DermatologyAcute Generalized Exanthematous Pustulosis: A Case Report.
CureusHospitalized generalized pustular psoriasis vs. acute generalized exanthematous pustulosis: A comprehensive analysis of clinical manifestations and treatment outcomes.
Chinese medical journalA Rare Presentation of Acute Generalized Exanthematous Pustulosis With Refractory Shock.
CureusPustular reaction in adult-onset immunodeficiency due to anti-interferon-gamma autoantibodies.
Frontiers in immunologyAcute generalized exanthematous pustulosis: 15-year retrospective multicentre experience.
Clinical and experimental dermatologyAntibiotics, analgesics and antifungals are commonly implicated in acute generalized exanthematous pustulosis; a retrospective analysis of 1410 cases.
Clinical and experimental dermatologyIomeprol-induced acute generalised exanthematous pustulosis (AGEP).
BMJ case reportsPenicillin Treatment in Infectious Mononucleosis May Lead to Persistent Drug Allergy in Adolescents and Adults Even after Years.
International archives of allergy and immunologyCombination testing confirming clindamycin induced acute generalized exanthematous pustulosis.
JAAD case reportsCase Report: Infliximab for hydroxychloroquine-induced AGEP with IL17A and IL36RN mutations: a case report and management considerations.
Frontiers in pharmacologyA Rare, Cephalosporin-induced Rash: Acute Generalized Exanthematous Pustulosis.
Journal of community hospital internal medicine perspectivesSevere cutaneous adverse reactions associated with novel antiandrogens: A disproportionality analysis of three databases.
International journal of cancerAcute generalized exanthematous pustulosis triggered by dupilumab.
Dermatology reportsAchieving Therapeutic Success with Spesolimab: Two Cases of Drug-Induced Generalized Pustular Psoriasis Initially Mimicking Acute Generalized Exanthematous Pustulosis.
Journal of inflammation researchA case of acute generalized exanthematous pustulosis following administration of nemolizumab.
JAAD case reportsLetter: when a Spider Bite Triggers a Dual Immune Response: Acute Generalized Exanthematous Pustulosis and Coombs-Positive Hemolytic Anemia.
Dermatitis : contact, atopic, occupational, drugPiperacillin-Tazobactam-Induced Generalized Exanthematous Pustulosis.
CureusEvaluation of combination therapy with secukinumab and systemic corticosteroids for acute generalized exanthematous pustulosis: A retrospective cohort study.
Journal of the American Academy of DermatologyAcute Generalized Exanthematous Pustulosis With Negative Patch Test and Drug-Induced Lymphocyte Stimulation Test (DLST) Results: A Case Report.
CureusAcute Generalized Exanthematous Pustulosis.
Journal of cutaneous medicine and surgeryAcute generalized exanthematous pustulosis associated with human parvovirus B19 infection.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious DiseasesMental health and psychosocial outcomes in survivors of severe cutaneous adverse reactions: a scoping review.
Clinical and experimental dermatologyAcute generalized exanthematous pustulosis induced by iodinated contrast media: a case report.
Dermatology reportsEffective Spesolimab Treatment for Generalized Pustular Psoriasis Masquerading as Acute Generalized Exanthematous Pustulosis: A Case Report.
CureusMosquito Bite as a Potential Novel Trigger for Acute Generalized Exanthematous Pustulosis (AGEP): A Case Report.
CureusDiseases of the IL-36 pathway.
The Journal of allergy and clinical immunologyGabapentin for refractory pruritus in severe cutaneous adverse reactions.
JAAD case reportsComparison of Acute Generalized Exanthematous Pustulosis with Maculopapular Rash in a Swiss Patient Cohort: A Single-Center Retrospective Study.
Dermatology (Basel, Switzerland)Acute Generalized Exanthematous Pustulosis in a Patient Treated With Bendamustine-Brentuximab Vedotin.
Dermatitis : contact, atopic, occupational, drugAcute Generalized Exanthematous Pustulosis Associated With Herpes Simplex Virus Reactivation Due to Cold Medicine: A Case Report and Review of the Literature.
CureusAcute Generalized Exanthematous Pustulosis Associated With Human Parvovirus B19 in an 11-Year-Old Girl.
Pediatric dermatologyAcute Generalized Exanthematous Pustulosis Following the Administration of Cephalexin: A Case Report and Review of the Literature.
CureusDemographics, Overlap, and Latency of Severe Cutaneous Adverse Reactions in an FDA Database.
medRxiv : the preprint server for health sciencesWhen Treatment Backfires: A Case Report of Sulfasalazine-Induced Hypersensitivity Syndrome in a Moroccan Patient With Crohn's Disease and Literature Review.
CureusAcute Generalized Exanthematous Pustulosis in a 76-year-Old Man With Neuroendocrine Carcinoma of the Lung, Responsive to Ixekizumab.
Clinical, cosmetic and investigational dermatologyRapid drug desensitization in seven patients with delayed hypersensitivity reactions to biologics and targeted therapies: Reason, successes, and failures.
Allergy and asthma proceedingsSingle-cell immunopathology of recurrent acute generalized exanthematous pustulosis associated with vancomycin.
The journal of allergy and clinical immunology. GlobalSevere Cutaneous Adverse Reactions Associated with Immune Checkpoint Inhibitors: A Systematic Review of Clinical Characteristics and Management.
Journal of cutaneous medicine and surgeryIL-36-driven pustulosis: Transcriptomic signatures match between generalized pustular psoriasis (GPP) and acute generalized exanthematous pustulosis (AGEP).
The Journal of allergy and clinical immunologySevere Cutaneous Adverse Reactions Following Vaccination: A Systematic Review and Meta-Analysis.
The journal of allergy and clinical immunology. In practice[Exanthematic drug eruption].
Pathologie (Heidelberg, Germany)Acute Generalized Exanthematous Pustulosis in a Patient With Crohn's Disease Being Treated for Streptococcal Pharyngitis and Sternoclavicular Joint Abscess.
CureusConfirmation of Metformin-Induced Acute Generalized Exanthematous Pustulosis Through a Positive Dechallenge-Rechallenge Test: A Case Report and Review of Cutaneous Manifestations Associated With Metformin.
CureusExpanding the therapeutic horizons of spesolimab: a review of off-label applications for inflammatory skin diseases.
The Journal of dermatological treatmentAcute generalised exanthematous pustulosis in a child.
BMJ case reportsIsotretinoin - Induced AGEP: A Case Report.
International medical case reports journalRare acute generalized exanthematous pustulosis caused by iodixanol: A case report.
MedicineMorbilliform Eruptions: Differentiating Low-Risk Drug Eruptions, Severe Cutaneous Adverse Reactions, Viral Eruptions, and Acute Graft-Versus-Host Disease.
American journal of clinical dermatologyHypersensitivity Reactions to Anticonvulsants.
Current allergy and asthma reportsVancomycin-induced acute generalised exanthematous pustulosis.
BMJ case reportsDiffuse pustules overlying brightly erythematous plaques in skin of color.
JAAD case reportsUnusual Presentation of Acute Generalized Exanthematous Pustulosis with Unilateral Anterior Trunk Involvement.
Sisli Etfal Hastanesi tip bulteniRecurrent pediatric acute generalized exanthematous pustulosis with drug and infective precipitants.
JAAD case reportsAcute Generalized Exanthematous Pustulosis Induced by Hyaluronic Acid Knee Injection: A Case Report.
Journal of emergency nursingAbrocitinib-induced acute generalized exanthematous pustulosis.
The Journal of dermatologyAcute generalized exanthematous pustulosis showing a discrepancy between results of patch test and drug-induced lymphocyte stimulation test.
The Journal of dermatologyA review on toxic epidermal necrolysis-like superficial wound lesions: Issue and challenge on 10 clinical entities.
International wound journalSpectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting.
Frontiers in allergyVancomycin and linezolid: severe cutaneous adverse reactions to drugs.
Expert opinion on drug safetyLevetiracetam and severe cutaneous adverse reactions: insights from FAERS database analysis.
Expert opinion on drug safetyTNF-α inhibitors as therapy for drug-induced severe cutaneous adverse reactions: a case series.
The Journal of dermatological treatmentSafety concerns of aztreonam: a real-world disproportionality analysis based on FDA Adverse Event Reporting System.
Expert opinion on drug safetyHydroxychloroquine-induced acute generalized exanthematous pustulosis with HLA-typing.
PharmacogenomicsValidation of the EuroSCAR criteria for acute generalized exanthematous pustulosis: A retrospective cohort study.
Journal of the American Academy of DermatologyAn Atypical Presentation of Acute Generalized Exanthematous Pustulosis Induced by Use of Meropenem: A Case Report and Literature Review.
CureusAcute generalized exanthematous pustulosis sine pustules following semaglutide injection.
JAAD case reportsAcute generalized exanthematous pustulosis induced by icotinib: a case report and literature review.
Frontiers in pharmacologySevere Acute Generalized Exanthematous Pustulosis Successfully Treated by Spesolimab.
Acta dermato-venereologicaAcute generalized exanthematous pustulosis following ceftriaxone.
Indian journal of pharmacologyAcute generalised exanthematous pustulosis and herpes simplex virus: a case of possible overlap.
BMJ case reportsThe Australasian Registry for Severe Cutaneous Adverse Reactions (AUS-SCAR) - Providing a roadmap for closing the diagnostic, patient, and healthcare gaps for a group of rare drug eruptions.
The World Allergy Organization journalClinical characteristics, treatment and outcome of clindamycin induced acute generalized exanthematous pustulosis.
Archives of dermatological researchDenosumab-induced Acute Generalized Exanthematous Pustulosis.
Acta dermato-venereologicaRapid Improvement in Refractory Acute Generalized Exanthematous Pustulosis With Spesolimab.
JAMA dermatologyAntibiotic-induced severe cutaneous adverse reactions: a single-center retrospective study over ten years.
Frontiers in immunologyAcute generalized exanthematous pustulosis triggered by COVID-19.
Dermatology online journalAcute generalized exanthematous pustulosis and generalized pustular psoriasis: not so different differentials?
International journal of dermatologyAcute generalized exanthematous pustulosis: European expert consensus for diagnosis and management.
Journal of the European Academy of Dermatology and Venereology : JEADVConcurrent Presentation of Eczema Herpeticum and Acute Localized Exanthematous Pustulosis in a Patient With Atopic Dermatitis: A Rare Dermatological Convergence.
CureusDelayed Skin Testing for Systemic Medications: Helpful or Not?
The journal of allergy and clinical immunology. In practiceAcute generalized exanthematous pustulosis secondary to dose-related turmeric supplementation.
Proceedings (Baylor University. Medical Center)Eczema herpeticum in an immunocompetent man.
Diagnostic microbiology and infectious diseaseDrug Reaction with Eosinophilia and Systemic Symptoms Induced by Diosmin and Hesperidin: A Case Report.
Clinical, cosmetic and investigational dermatologyEvolution of the spectrum of drugs associated with acute generalized exanthematous pustulosis over time: A pharmacovigilance study.
Journal of the American Academy of DermatologyLower extremity purpura as an uncommon presentation of acute generalized exanthematous pustulosis (AGEP).
International journal of dermatologyCOVID-19 and Autoimmunity in Dermatology: A Moroccan Case Series and Literature Review.
CureusAn unusual adverse effect during crusted scabies treatment.
Clinical case reportsSevere cutaneous adverse reactions.
Nature reviews. Disease primersRecognizing rare rashes: A case of acute generalized exanthematous pustulosis.
JAAPA : official journal of the American Academy of Physician AssistantsGenetic analysis of different subtypes of aseptic pustulosis in the Chinese population.
Clinical and experimental dermatologyIL36RN mutations in Chinese patients with acute generalized exanthematous pustulosis.
International journal of dermatologyTrips Through the Skin: Reviewing Cutaneous Drug Reactions to Psychedelics and Hallucinogens.
Dermatitis : contact, atopic, occupational, drugA rare case of acute generalized exanthematous pustulosis induced by gadobutrol.
Contact dermatitisEvaluation of the frequency and characteristics of drug hypersensitivity reactions in hospitalized children: Real life-cohort study.
The World Allergy Organization journalIcodextrin-induced acute generalized exanthematous pustulosis in a patient with peritoneal dialysis.
Nephrology (Carlton, Vic.)A Case of Diltiazem-Induced Pustular Rash in an 83-Year-Old Female.
Case reports in dermatological medicineCase Report: Kawasaki disease associated with acute generalized exanthematous pustulosis secondary to carbocysteine.
Frontiers in pediatricsSevere cutaneous adverse reactions associated with the immune checkpoint inhibitors: A case/non-case analysis using the Food and Drug Administration Adverse Event Reporting System.
The Australasian journal of dermatologyA case of acute generalized exanthematous pustulosis caused by eperisone hydrochloride.
European journal of dermatology : EJDSevere cutaneous adverse reactions in a tertiary care center in Jamaica.
JAAD internationalFirst episode of generalized pustular psoriasis or acute generalized exanthematous pustulosis? A case study.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDGCelecoxib-induced acute generalized exanthematous pustulosis: uncommon and under-recognized side effect.
EXCLI journalDifferentiating generalized pustular psoriasis from acute generalized exanthematous pustulosis.
Journal of the American Academy of DermatologyGeneralized Pustular Psoriasis, Acute Generalized Exanthematous Pustulosis, and Other Pustular Reactions: A Clinical Review.
Dermatologic clinicsHydroxychloroquine-induced acute generalized exanthematous pustulosis (AGEP) treated with secukinumab.
Journal of the European Academy of Dermatology and Venereology : JEADVA case report of terbinafine-induced acute generalized exanthematous pustulosis in a striking photodistributed pattern.
SAGE open medical case reportsExanthematous Pustulosis Restricted to Striae Distensae.
Journal of cutaneous medicine and surgeryAcute Generalized Exanthematous Pustulosis Induced by a Jellyfish Sting (Rhizostoma pulmo).
Dermatitis : contact, atopic, occupational, drugMultiple drug hypersensitivity syndrome manifesting as acute generalised exanthematous pustulosis: A rare case report.
Contact dermatitisEthical considerations in the management of drug severe cutaneous adverse reactions.
Journal of the American Academy of DermatologyAcute Generalized Exanthematous Pustulosis in a Hemodialysis Patient.
CureusMedication Associations With Severe Cutaneous Adverse Reactions: A Case/Non-Case Analysis Using the FDA Adverse Event Reporting System.
Journal of cutaneous medicine and surgerySevere cutaneous adverse drug reactions: incidence, clinical characteristics, treatment, and outcome in pediatric patients.
Asian Pacific journal of allergy and immunologyUnusual cutaneous adverse reaction to an erectile dysfunction drug: A case report.
Urology case reportsAn observational study of severe cutaneous adverse reactions at a tertiary care teaching hospital.
Medical journal, Armed Forces IndiaGeneralized pustulosis following Covid 19 vaccination in a patient in treatment with adalimumab.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDGAcute generalized exanthematous pustulosis: Analysis of cases managed in a Tunisian tertiary hospital.
TherapieMarginal corneal infiltrates as an ocular manifestation of acute generalized exanthematous pustulosis.
American journal of ophthalmology case reportsAcute generalized exanthematous pustulosis caused by hydroxychloroquine in a patient with rheumatoid arthritis and CARD14 mutation: Case report.
MedicineAcute localised exanthematous pustulosis (ALEP)-induced by ioversol.
Contact dermatitisCutaneous adverse drug reactions.
TherapieAcute generalized exanthematous pustulosis induced by Ambroxol confirmed by positive skin tests.
Contact dermatitisClinicopathological characteristics of cutaneous complications following COVID-19 vaccination: A case series.
Journal of cosmetic dermatologyRapid Clearance of Corticosteroid-Resistant Targetoid Acute Generalized Exanthematous Pustulosis Using an IL-17A Inhibitor: A Case Report.
Journal of investigational allergology & clinical immunologyAssociation between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactions.
Frontiers in pharmacologyA case of acute localized exanthematous pustulosis following COVID-19 infection.
The Journal of dermatologyCharacteristics of mild and severe apalutamide-related cutaneous adverse events in patients with prostate cancer: A review of the literature.
The Journal of dermatologyGuideline for allergological diagnosis of drug hypersensitivity reactions: S2k Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Dermatological Society (DDG), the Association of German Allergologists (ÄDA), the German Society for Pediatric Allergology (GPA), the German Contact Dermatitis Research Group (DKG), the German Society for Pneumology (DGP), the German Society of Otorhinolaryngology, Head and Neck Surgery, the Austrian Society of Allergology and Immunology (ÖGAI), the Austrian Society of Dermatology and Venereology (ÖGDV), the German Academy of Allergology and Environmental Medicine (DAAU), and the German Documentation Center for Severe Skin Reactions (dZh).
Allergologie selectNaltrexone-induced acute generalized exanthematous pustulosis.
JAAD case reportsA Rare Dermatologic Reaction in an Adult Patient Following Coronary Angiography: Acute Generalized Exanthematous Pustulosis.
The journal of Tehran Heart CenterPustular Eruption following COVID-19 Vaccination: A Narrative Case-Based Review.
VaccinesStevens-johnson Syndrome and Toxic Epidermal Necrolysis: An Overview of Diagnosis, Therapy Options and Prognosis of Patients.
Recent advances in inflammation & allergy drug discoveryDermatologic toxicities to inhibitors of cyclin-dependent kinases CDK 4 and 6: An updated review for clinical practice.
Annales de dermatologie et de venereologieAcute generalized exanthematous pustulosis induced by exemestane during adjuvant radiotherapy for breast cancer.
Medicina clinicaImmune Reactions in Major Types of Oncological Treatment.
International journal of molecular sciencesHydroxychloroquine-induced repetitive atypical pustular drug eruptions in the same patient separated by 12 years.
Clinical case reportsAcute generalized exanthematous pustulosis secondary to mianserin with liver involvement.
European journal of dermatology : EJDAcute generalized exanthematous pustulosis associated with clindamycin in a patient with Hailey-Hailey disease.
Journal of cutaneous pathologyAzathioprine hypersensitivity: A Sweet-like syndrome.
International journal of rheumatic diseasesAcute generalized exanthematous pustulosis with systemic involvement.
Journal of osteopathic medicineDrug Hypersensitivity Reactions.
Immunology and allergy clinics of North AmericaAcquired cutis laxa secondary to acute generalized exanthematous pustulosis: A case report and mini-review of literature.
The Journal of dermatology[Identification of cutaneous adverse drug reactions].
La Revue du praticienDeadly drug rashes: Early recognition and multidisciplinary care.
Cleveland Clinic journal of medicineA case of acute generalized exanthematous pustulosis following COVID-19 infection and remdesivir.
Clinical case reportsAcute localized exanthematous pustulosis induced by fosfomycin.
JAAD case reportsKey factors predicting the in-hospital mortality of patients with severe cutaneous adverse reactions in Thailand.
Journal of the European Academy of Dermatology and Venereology : JEADVSevere Cutaneous Adverse Drug Reactions at a Tertiary Care Center in Saudi Arabia.
Dermatology research and practiceSorafenib-Induced Acute Generalized Exanthematous Pustulosis.
Dermatology practical & conceptualCurrent understanding of genetic associations with delayed hypersensitivity reactions induced by antibiotics and anti-osteoporotic drugs.
Frontiers in pharmacologyAcute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management.
American journal of clinical dermatologyAcute generalized exanthematous pustulosis complicated by cutaneous small vessel vasculitis: A case report and literature review.
The Australasian journal of dermatologyParacetamol (Acetaminophen)-associated SJS, TEN, AGEP, and DRESS Syndromes - A Narrative Review.
Current drug safetyClinical features of acute generalized exanthematous pustulosis caused by hydroxychloroquine in rheumatology patients and exploration of CARD14 gene mutations.
Frontiers in medicineAcute generalized exanthematous pustulosis in a patient with COVID-19 infection.
Journal of the European Academy of Dermatology and Venereology : JEADVVarenicline-induced drug eruption: case and review of the literature.
Dermatology online journalConcurrent acute generalized exanthematous pustulosis in siblings.
Pediatric dermatologySevere Cutaneous Adverse Reaction Caused by Carbamazepine and Levofloxacin After Varicella Zoster Virus Infection.
Infection and drug resistanceCutaneous candidiasis mimicking acute generalized exanthematous pustulosis: A case report.
SAGE open medical case reportsA Case Report of Possibly Related Acute Generalized Exanthematous Pustulosis with Staphylococcus pettenkoferi.
Clinical, cosmetic and investigational dermatologyA Case of Acute Generalized Exanthematous Pustulosis Induced by Ceftriaxone.
CureusGeneralized Pustular Figurate Erythema in Patients with COVID-19 Treated with Hydroxychloroquine: A Systematic Review.
Acta dermatovenerologica Croatica : ADCAcute Localized Exanthematous Pustulosis Induced by a Spider Bite.
Dermatitis : contact, atopic, occupational, drugAcute Localized Exanthematous Pustulosis (ALEP) Caused by Topical Application of Minoxidil.
Journal of clinical medicineAcute generalized exanthematous pustulosis: Clinico-biological profile and inducing drugs in 83 patients.
Journal of the European Academy of Dermatology and Venereology : JEADVAcute Generalized Exanthematous Pustulosis: Clinical Characteristics, Pathogenesis, and Management.
Dermatology (Basel, Switzerland)Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators.
BiomedicinesTerbinafine Induced Acute Generalized Exanthematous Pustulosis Treated with Adalimumab: Recalcitrant to Systemic Corticosteroid Therapy.
Clinical, cosmetic and investigational dermatologyThe Man of a Thousand Pustules: A Case About Acute Generalized Exanthematous Pustulosis.
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Acute Generalized Exanthematous Pustulosis in a Neonate Following Hepatitis B Vaccination: A Case Report.
- The Hidden Perils of Allopurinol: A Systematic Review of Allopurinol-Induced DRESS (Drug Reaction With Eosinophilia and Systemic Symptoms) Syndrome.
- A Systematic Review of Pediatric Acute Generalized Exanthematous Pustulosis.
- Acute Generalized Exanthematous Pustulosis: An Integrated Study of 503 Cases with Emphasis on Drug Culprits, Clinical Features, Diagnosis and Treatment.
- Iodinated Contrast-Induced AGEP and ALEP: Recognition, Diagnosis, and Management.
- Concurrent Drug-induced Rowell Syndrome and Acute Generalized Exanthematous Pustulosis.
- A 69-year-old man with acute generalized exanthematous pustulosis.
- An Unusual Case of Drug-Induced Hypersensitivity Syndrome With Multiple Atypical Histopathologic Findings.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:293173(Orphanet)
- MONDO:0017384(MONDO)
- GARD:21164(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q1980528(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
