A Síndrome do Encarceramento (LIS) é uma condição neurológica em que a pessoa mantém os olhos abertos, mas apresenta paralisia total ou parcial dos quatro membros (braços e pernas) e incapacidade de falar. Apesar disso, a capacidade de pensar e compreender permanece intacta, e a comunicação principal se dá por meio de movimentos verticais dos olhos ou piscadas.
Introdução
O que você precisa saber de cara
A Síndrome do Encarceramento (LIS) é uma condição neurológica em que a pessoa mantém os olhos abertos, mas apresenta paralisia total ou parcial dos quatro membros (braços e pernas) e incapacidade de falar. Apesar disso, a capacidade de pensar e compreender permanece intacta, e a comunicação principal se dá por meio de movimentos verticais dos olhos ou piscadas.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 7 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 16 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
Triagem neonatal (Teste do Pezinho)
A triagem neonatal permite diagnóstico precoce e início imediato do tratamento.
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Síndrome de encarceramento
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
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Outros ensaios clínicos
21 ensaios clínicos encontrados, 8 ativos.
Publicações mais relevantes
Advancing the science of consciousness: From ethics to clinical care.
Significant advances in the scientific investigation of the neurobiology of consciousness have been slow to be translated into clinical settings, limited by a lack of generally agreed working definition (e.g., what is consciousness?) and methodology (e.g., how to identify reliable biomarkers/indicators of consciousness? How to improve sensitivity and specificity of the technological identification of consciousness?). In the present paper we aim at proposing potential strategies for reducing the gap between research, clinical practice, and patients' and their caregivers' needs regarding disorders of consciousness. By implementing a multidisciplinary (i.e., involving different disciplines) and multiperspective (i.e., involving different stakeholders) approach, the paper focuses on disorders of consciousness: it starts from the review of some of the most promising measures of consciousness from brain activity (i.e., electrophysiology and spectral measures, measures of functional connectivity, complexity-based measures). Next the paper introduces brain responses to illusions as a possible new indicator of consciousness (i.e., a feature that facilitates the attribution of consciousness), and illustrates a possible clinical operationalization of the indicators of consciousness through the case of virtual reality. Finally, the paper analyses a set of urgent ethical issues and describes a model for assessing and dealing with those issues, concluding by elaborating key recommendations for improving the clinical treatment of patients with disorders of consciousness through a better translation of research into clinics.
Large-scale training data enhances silent speech decoding with around-ear EEG.

 Silent speech decoding (SSD) offers a potential communication alternative for individuals with impaired vocalization. However, conventional multi-electrode electroencephalography (EEG) or facial electromyography (EMG) systems require cumbersome preparation and are unsuitable for daily use. This study evaluates the practicality of SSD using a wearable around-ear EEG device, focusing on data scaling, cross-subject transfer, vocabulary extensibility, and online decoding performance.
Approach.
 We collected 72 hours of around-ear EEG from 24 healthy participants and one individual with incomplete locked-in syndrome (LIS) during silent, vocalized, and attempted speech, and integrated these around-ear EEG recordings with prior EMG + high-density EEG datasets, yielding 282.4 total hours of training data. Using a 64-word classification task as the evaluation metric, we assessed: (1) whether larger datasets improve around-ear EEG-based SSD, (2) whether healthy-participant data supplement limited LIS-participant data despite articulatory differences, (3) transferability to unseen vocabulary, and (4) online user-interface performance.
Main results.
 Large-scale EEG/EMG data improved SSD accuracy in both healthy participants and the LIS participant. Training on the heterogeneous dataset achieved 56.6% accuracy for healthy users and 47.3% for the LIS participant. Fine-tuning this decoder for new vocabulary increased the accuracy by 22 percentage points relative to training from scratch. Regression analysis showed that, for decoding in the LIS participant, data from the LIS participant contributed approximately four times the weight of healthy-participant data, quantifying data strategies for SSD. Online experiments achieved top-1/top-5 accuracies of 47.2%/76.0% for healthy users and 26.5%/49.1% for the LIS participant.
Significance.
 The results indicate that lightweight, commercially feasible around-ear EEG can enable practical SSD when combined with large-scale healthy-participant data, supporting online operation. Moreover, models trained on a 64-word vocabulary facilitate decoding of a new vocabulary, providing a path toward SSD systems requiring minimal LIS-participant data. This study advances non-invasive silent speech decoding systems suitable for everyday communication.
A visual imagery paradigm for BCI strategies using imagined flickering patterns.
Steady state visually evoked potentials (SSVEPs) are a popular type of control signals in brain-computer interfaces (BCIs), in which they are typically elicited by observing a visual stimulus flashing at a specific frequency. For some patients, using SSVEP as control signal for a BCI can be difficult, for instance if they are unable to focus their gaze over the visual stimuli. To address this issue, some approaches were presented to design a gaze-independent SSVEP-controlled BCI but some difficulties have been reported, for instance for patients suffering from locked-in syndrome. In this work we employ a visual imagery (VI) signal, in which the visual stimulus is imagined instead of observed, to drive a BCI system and offer an alternative for patients that encounter issues with standard SSVEP approaches. We tested the proposed approach with 20 untrained subjects within a 3-classes BCI resulting in an offline classification accuracy of 60.93%. These results demonstrate how this gaze-independent BCI can be used by inexperienced BCI users.
Implantable Neural Speech Decoders: Recent Advances, Future Challenges.
The social life of locked-in syndrome (LIS) patients is significantly impacted by their difficulties to communicate. Consequently, researchers have started to explore how to decode intended speech from neural signals directly recorded from the cortex. The first studies in the late 2000s reported modest decoding accuracies. However, thanks to fast advances in machine learning, the most recent studies have reached decoding accuracies high enough to be optimistic about the clinical benefit of neural speech decoders in the near future. We first discuss the selection criteria for implanting a neural speech decoder in LIS patients, emphasizing the advantages and disadvantages associated with conditions such as brainstem stroke and amyotrophic lateral sclerosis. We examine the key design considerations for neural speech decoders, demonstrating how successful implantation requires careful optimization of multiple interrelated factors including language representation, cortical recording areas, neural features, training paradigms, and decoding algorithms. We then discuss current approaches and provide arguments for potential improvements in decoder design and implementation. Finally, we explore the crucial question of who should learn to use the neural speech decoder-the patient, the machine, or both. In conclusion, while neural speech decoders present promising avenues for improving communication for LIS patients, interdisciplinary efforts spanning neurorehabilitation, neuroscience, neuroengineering, and ethics are imperative to design future clinical trials.
Central pontine myelinolysis in diffuse large B-cell lymphoma, a case series and literature review.
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma in Saudi Arabia. Osmotic demyelination syndrome (ODS) is divided into central pontine myelinolysis (CPM) and extrapontine myelinolysis. The occurrence of osmotic demyelination syndrome is classically described in the setting of rapid correction of hyponatremia. Clinical Manifestations are variable, ranging from asymptomatic cases to quadriparesis and locked-in syndrome in the severe form. We reported a total of six cases with diffuse large B-cell lymphoma (DLBCL) that developed central pontine myelinolysis. A literature review was done reviewing all case reports of central pontine myelinolysis occurring in patients with non-Hodgkin lymphoma. A total of 16 patients were reviewed, including our six cases and ten patients from published reports. Nine out of 16 were asymptomatic (56.3%), and DLBCL was present in all cases except one (93.8%). Risk factors such as fluctuations in osmolality or hypoalbuminemia were documented in 9 out of the 16 cases (65.3%), and none had undergone overly rapid sodium correction. The outcome was favorable in all cases, with no residual neurological deficits. DLBCL can predispose to pontine changes suggestive of CPM with a relatively favorable prognosis. The nature of these changes remains uncertain due to lack of histopathological confirmation.
Publicações recentes
Decoding intended speech with an intracortical brain-computer interface in a person with long-standing anarthria and locked-in syndrome.
Brainstem control of sleep, wakefulness, alertness, and consciousness.
Brain death and the brainstem.
Large-scale training data enhances silent speech decoding with around-ear EEG.
📚 EuropePMC493 artigos no totalmostrando 194
Large-scale training data enhances silent speech decoding with around-ear EEG.
Journal of neural engineeringA visual imagery paradigm for BCI strategies using imagined flickering patterns.
Scientific reportsBrain-computer interfaces: a new horizon in communication for locked-in syndrome.
Annals of medicine and surgery (2012)Central pontine myelinolysis in diffuse large B-cell lymphoma, a case series and literature review.
BMC neurologyConsensus on covert awareness: a Delphi study.
Brain communicationsHarmonic Component Analysis: A novel training-free and asynchronous BCI classification method.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International ConferenceA Novel Approach to Improve SSVEP-BCI Performance Through Neurofeedback Training.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International ConferenceEmpowering Accessibility: Human-Centered Approach to a BCI Home Control for Impaired People.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International ConferenceAdvancing the science of consciousness: From ethics to clinical care.
Neuroscience and biobehavioral reviewsDisorder of consciousness rather than complete Locked-In Syndrome for end stage Amyotrophic Lateral Sclerosis: a case series.
Communications medicineAssessing consciousness in patients with locked-in syndrome using their EEG.
Frontiers in neuroscienceCovert consciousness: what's in a name?
Brain : a journal of neurologyReal-time detection of spoken speech from unlabeled ECoG signals: a pilot study with an ALS participant.
Journal of neural engineeringImplantable Neural Speech Decoders: Recent Advances, Future Challenges.
Neurorehabilitation and neural repairAssessing Capacity and Exploring Goals of Care in Locked-In Syndrome: A Clinician's Guide.
Neurology. Clinical practiceJahi McMath case: A comprehensive and updated narrative.
World journal of critical care medicineDecoding intended speech with an intracortical brain-computer interface in a person with longstanding anarthria and locked-in syndrome.
bioRxiv : the preprint server for biologyDon't put words in my mouth: speech perception can falsely activate a brain-computer interface.
Journal of neuroengineering and rehabilitationLegal personhood and legal capacity: the case of the locked-in syndrome.
Journal of law and the biosciencesCatatonia: American Psychiatric Association Resource Document.
Journal of the Academy of Consultation-Liaison PsychiatryThe effectiveness of FOUR score versus GCS scale in predicting mortality and morbidity in traumatic brain injured patients in intensive care: A systematic review.
Intensive & critical care nursingImpact of communication modalities on autonomy and social participation of persons with locked-in syndrome.
Brain impairment : a multidisciplinary journal of the Australian Society for the Study of Brain ImpairmentSimulating online and offline tasks using hybrid cheetah optimization algorithm for patients affected by neurodegenerative diseases.
Scientific reportsBilateral medial medullary and spinal cord infarctions presenting as locked-in syndrome in an adolescent with primary antiphospholipid syndrome.
BMJ case reportsDesigning an online BCI forum: insights from researchers and end-users.
Journal of neural engineeringPan-neurofascin autoimmune nodoparanodopathy: A case report and literature review.
MedicineA novel non-invasive EEG-SSVEP diagnostic tool for color vision deficiency in individuals with locked-in syndrome.
Frontiers in bioengineering and biotechnologyDecoding speech intent from non-frontal cortical areas.
Journal of neural engineeringRSVP keyboard with inquiry preview: mixed performance and user experience with an adaptive, multimodal typing interface combining EEG and switch input.
Journal of neural engineeringGood results of neurorehabilitation of ischaemic stroke - locked-in syndrome in a pregnant woman with delivery of healthy child.
Neurologia i neurochirurgia polskaPredicting attentional focus: Heartbeat-evoked responses and brain dynamics during interoceptive and exteroceptive processing.
PNAS nexusA Case of Guillain-Barré Syndrome and Repurposing cEEG to Enable Communication in Total Locked-in Syndrome.
Neurocritical careBrain Function and Structure Changes in the Prognosis Prediction of Prolonged Disorders of Consciousness.
Brain topographyFrom locked-in syndrome to recovery: thrombolysis success in bilateral pontine infarction with 'heart appearance' sign.
BMJ case reports[Diagnosis, Notification, and Managements of ALS: A Personal Perspective from 40 years of Experience as a Clinical Neurologist].
Brain and nerve = Shinkei kenkyu no shinpoDO NOT LOSE SLEEP OVER IT: IMPLANTED BRAIN-COMPUTER INTERFACE FUNCTIONALITY DURING NIGHTTIME IN LATE-STAGE AMYOTROPHIC LATERAL SCLEROSIS.
medRxiv : the preprint server for health sciencesBrain-Computer Interfaces with Intracortical Implants for Motor and Communication Functions Compensation: Review of Recent Developments.
Sovremennye tekhnologii v meditsineClinical and ethical challenges in decision-making for patients with disorders of consciousness and locked-in syndrome from Chinese neurologists' perspectives.
Therapeutic advances in neurological disordersWithdrawal of Life-Sustaining Mechanical Ventilation for a Patient With Amyotrophic Lateral Sclerosis in Locked-In Syndrome.
Journal of clinical neurology (Seoul, Korea)Iterative alignment discovery of speech-associated neural activity.
Journal of neural engineeringLocked-in Syndrome Due to Isolated Basilar Artery Dissection.
RadiologyDilemma in patients with amyotrophic lateral sclerosis and expectations from brain-machine interfaces.
Annals of medicineLocked-in syndrome: A qualitative study of a life story.
Brain and behaviorA review on the performance of brain-computer interface systems used for patients with locked-in and completely locked-in syndrome.
Cognitive neurodynamics[Recovery from locked-in syndrome: rule rather than exception].
Nederlands tijdschrift voor geneeskundeRapidly progressive locked-in syndrome secondary to atypical herpes simplex virus-1 rhombencephalitis in an immunocompromised individual.
IDCasesLocked-In Syndrome: A Rare Manifestation of Neuropsychiatric Lupus.
CureusHigh Doses of Caffeine-Induced Cerebral Infarction Leading to Partial Locked-In Syndrome in a Young Adult: A Novel Association?
Case reports in neurologyThe ethical significance of user-control in AI-driven speech-BCIs: a narrative review.
Frontiers in human neuroscienceLocked-in Syndrome After Pontine Hemorrhage in an Amphetamine Abuser.
Deutsches Arzteblatt internationalCorrecting for ERP latency jitter improves gaze-independent BCI decoding.
Journal of neural engineeringFacile Electret-Based Self-Powered Soft Sensor for Noncontact Positioning and Information Translation.
ACS applied materials & interfacesBrain-to-brain interface technology: A brief history, current state, and future goals.
International journal of developmental neuroscience : the official journal of the International Society for Developmental NeuroscienceLocked-in syndrome following elective cervical foraminotomy: a case report.
Spinal cord series and casesNeural signatures of imaginary motivational states: desire for music, movement and social play.
Brain topographyDeveloper perspectives on the ethics of AI-driven neural implants: a qualitative study.
Scientific reportsTransient Locked-in Syndrome after Aneurysmal Subarachnoid Bleeding due to Spasm Hypoxemia?
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine[Listeria meningoencephalitis resulting in complete bilateral ophtalmoplegia and locked-in syndrome].
Zhurnal nevrologii i psikhiatrii imeni S.S. KorsakovaA scoping review of gaze and eye tracking-based control methods for assistive robotic arms.
Frontiers in robotics and AIAnesthetic Considerations for Patients with Locked-In Syndrome Undergoing Endoscopic Procedures.
The American journal of case reportsLocked-in syndrome after central pontine myelinolysis, an outstanding outcome of two patients.
Annals of clinical and translational neurology[‘Locked-in syndrome’ in Norwegian].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekkeUpdate on How to Approach a Patient with Locked-In Syndrome and Their Communication Ability.
Brain sciencesThe challenge of controlling an auditory BCI in the case of severe motor disability.
Journal of neuroengineering and rehabilitationA Brain-Controlled Quadruped Robot: A Proof-of-Concept Demonstration.
Sensors (Basel, Switzerland)Severe osmotic demyelination syndrome with cortical involvement in the context of severe hyponatremia and central diabetes insipidus: an uncommon presentation of an unusual combination.
BMJ case reportsAnti-GQ1b Antibody Syndrome Presented as Locked-In Syndrome: A Rare Case Report.
CureusThe vascular locked-in and locked-in-plus syndrome: A retrospective case series.
Therapeutic advances in neurological disordersAtypical Presentation of the Classical Form of Locked-In Syndrome in a Young Patient.
Journal of investigative medicine high impact case reportsBoosting brain-computer interfaces with functional electrical stimulation: potential applications in people with locked-in syndrome.
Journal of neuroengineering and rehabilitationCommunication board in locked-in syndrome: a practical interaction method with the patient.
Dementia & neuropsychologiaOsmotic Demyelination Syndrome: A Rare Clinical Image.
Diagnostics (Basel, Switzerland)It takes two (seconds): decreasing encoding time for two-choice functional near-infrared spectroscopy brain-computer interface communication.
NeurophotonicsNeuroscience of consciousness in the locked-in syndrome: Prognostic and diagnostic review.
IbrainMassive body-brain disconnection consequent to spinal cord injuries drives profound changes in higher-order cognitive and emotional functions: A PRISMA scoping review.
Neuroscience and biobehavioral reviewsUsing fMRI to localize target regions for implanted brain-computer interfaces in locked-in syndrome.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyMoral Uncertainty and Our Relationships with Unknown Minds.
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committeesAltered brain dynamics index levels of arousal in complete locked-in syndrome.
Communications biologyBrain-Computer Interfaces, Completely Locked-In State in Neurodegenerative Diseases, and End-of-Life Decisions.
Journal of bioethical inquiryAssessing consciousness in patients with disorders of consciousness using soft-clustering.
Brain informaticsDemographic, Medical, and Clinical Characteristics of a Population-Based Sample of Patients With Long-lasting Locked-In Syndrome.
NeurologyLocked-in syndrome caused by extracranial and intracranial takayasu arteritis: A rare case report and radiological findings.
Radiology case reportsMultidimensional assessment of heartbeat-evoked responses in disorders of consciousness.
The European journal of neuroscienceRapid Correction of Hyponatremia With Isotonic Saline Leading to Central Pontine Myelinolysis.
CureusHeroin-Induced Leukoencephalopathy Leading to Locked-In Syndrome: A Case Report.
CureusAssessment and management of pain/nociception in patients with disorders of consciousness or locked-in syndrome: A narrative review.
Frontiers in systems neuroscienceLocked-in syndrome revisited.
Therapeutic advances in neurological disordersReligiosity in patients with amyotrophic lateral sclerosis, a cross-country comparison.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitationUnderstanding the Psychological Well-being of Patients With Locked-in Syndrome: A Scoping Review.
CureusCentral pontine myelinolysis and locked-IN syndrome associated with tacrolimus after pediatric heart transplantation.
Pediatric transplantationApplication of Soft-Clustering to Assess Consciousness in a CLIS Patient.
Brain sciencesEvent-related brain potential markers of visual and auditory perception: A useful tool for brain computer interface systems.
Frontiers in behavioral neuroscience[Let's Watch the Movie, The Diving Bell and the Butterfly and Think About the Patient's Feelings].
Brain and nerve = Shinkei kenkyu no shinpoSubacute brainstem ischemic syndrome in juvenile neurofibromatosis type 2: An underrecognized condition.
Clinical case reportsWriting Blindly in Incomplete Locked-In Syndrome with A Custom-Made Switch-Operated Voice-Scanning Communicator-A Case Report.
Brain sciencesDevelopment of Parkinsonism in a Patient with Central Pontine Myelinolysis.
Neurology internationalMethodological Recommendations for Studies on the Daily Life Implementation of Implantable Communication-Brain-Computer Interfaces for Individuals With Locked-in Syndrome.
Neurorehabilitation and neural repairA 44-Year-Old Alcohol-Dependent Man Who Recovered from Central Pontine Myelinolysis with Supportive Physical Therapy.
The American journal of case reportsSlow Firing Single Units Are Essential for Optimal Decoding of Silent Speech.
Frontiers in human neuroscienceLocked-in syndrome responding to endovascular treatment.
Journal of neurointerventional surgeryA systematic review of research on augmentative and alternative communication brain-computer interface systems for individuals with disabilities.
Frontiers in human neuroscienceTowards predicting ECoG-BCI performance: assessing the potential of scalp-EEG.
Journal of neural engineeringAcute vertical pendular nystagmus: eye-movement analysis and review of the literature.
Journal of neurologyThe locked-in syndrome: The early French descriptions.
Revue neurologiqueOptimizing Motor Imagery Parameters for Robotic Arm Control by Brain-Computer Interface.
Brain sciencesPosttraumatic locked-in syndrome from combined brainstem and upper cervical injury in childhood: A case report.
Neuro-ChirurgieWho gets to decide?: Substitute decision making following severe brain injury with communication impairment.
Neuropsychological rehabilitationA unique case of free-floating gastric band tubing causing intraabdominal sepsis in a patient with locked-in syndrome secondary to Guillain-Barré syndrome.
Journal of surgical case reportsFrench Survey on Pain Perception and Management in Patients with Locked-In Syndrome.
Diagnostics (Basel, Switzerland)Dramatic neuromuscular paralysis following occult snakebites: An awareness for the primary care physician.
Journal of family medicine and primary careMechanical thrombectomy via chronic occluded proximal artery for the endovascular treatment of acute ischemic stroke patients with large vessel occlusion.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaInvestigating Structure-Function Connectivity in a Patient With Locked-In Syndrome by 7 T Magnetic Resonance Imaging: A Case Report.
The neurologistBrain-Computer Interface: Applications to Speech Decoding and Synthesis to Augment Communication.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsSnakebite Mimicking Brain Death: Bedside Clues.
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care MedicineSee, Hear, or Feel - to Speak: A Versatile Multiple-Choice Functional Near-Infrared Spectroscopy-Brain-Computer Interface Feasible With Visual, Auditory, or Tactile Instructions.
Frontiers in human neuroscienceControl and Ownership of Neuroprosthetic Speech.
Philosophy & technologyLocked-in Syndrome Due to Meningovascular Syphilis: A Case Report and Literature Review.
Internal medicine (Tokyo, Japan)Decoding four hand gestures with a single bipolar pair of electrocorticography electrodes.
Journal of neural engineeringLocked-In Syndrome: A Systematic Review of Long-Term Management and Prognosis.
CureusBrain-Computer interfaces for communication: preferences of individuals with locked-in syndrome, caregivers and researchers.
Disability and rehabilitation. Assistive technologyLocked-In Syndrome after Traumatic Basilar Artery Entrapment within a Clivus Fracture: A Case Report and Review of the Literature.
Neurotrauma reportsProbable first report of a motor deafferentation syndrome in the Paraguayan War.
Arquivos de neuro-psiquiatriaA Case of Central Pontine Myelinolysis Occurred During Treatment of Hyperosmolar Hyperglycemic Syndrome.
International medical case reports journalThe clinical and cognitive spectrum of locked-in syndrome: 1-year follow-up of 100 patients.
Acta neurologica BelgicaThinking without speaking: Neuropsychological testing with individuals who have communication impairments.
Neuropsychological rehabilitation[Hikikomori and locked-in syndrome].
MedicinaIsolated basilar artery dissection following blunt trauma challenging the Glasgow coma score: A case report.
The American journal of emergency medicineNeurophysiological aspects of the completely locked-in syndrome in patients with advanced amyotrophic lateral sclerosis.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyTransient total locked-in syndrome due to vertebral and basilar artery dissection.
BMJ case reportsA clinical characteristic analysis of five cases of rare bilateral cerebral peduncular infarction (BCPI) with the 'Mickey Mouse ears' sign.
Brain injuryBrain-Computer Interfaces for Communication: Preferences of Individuals With Locked-in Syndrome.
Neurorehabilitation and neural repairCorrigendum: Performance Differences Using a Vibro-Tactile P300 BCI in LIS-Patients Diagnosed With Stroke and ALS.
Frontiers in neuroscienceLocked-In Syndrome: Practical Rehabilitation Management.
PM & R : the journal of injury, function, and rehabilitationThe multiplicity of caregiving burden: a qualitative analysis of families with prolonged disorders of consciousness.
Brain injuryConsciousness Detection in a Complete Locked-in Syndrome Patient through Multiscale Approach Analysis.
Entropy (Basel, Switzerland)False-Negative Initial Magnetic Resonance Imaging in Acute Posterior Circulation Stroke: A Case Report Describing Locked-in Syndrome.
CureusIsolated Bilateral Cerebral Peduncular Infarction Manifesting Pseudobulbar Palsy and Quadriparesis: a Case Report.
Brain & NeuroRehabilitationAre intrinsic neural timescales related to sensory processing? Evidence from abnormal behavioral states.
NeuroImageLocked-in Syndrome in a Young Patient Due to SARS-CoV-2: A Case Report.
Frontiers in medicineSevere Locked-In-Like Guillain-Barré's Syndrome: Dilemmas in Diagnosis and Treatment.
NeuropediatricsDiffuse cerebral angiomatosis associated to basilar apex aneurysm.
British journal of neurosurgeryElectrophysiological and Neuroimaging Studies - During Resting State and Sensory Stimulation in Disorders of Consciousness: A Review.
Frontiers in neuroscienceTest-Retest Reliability of Time-Domain EEG Features to Assess Cognitive Load Using a Wireless Dry-Electrode System.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International ConferenceDorsolateral prefrontal cortex-based control with an implanted brain-computer interface.
Scientific reports"Re-identifying yourself": a qualitative study of veteran views on implantable BCI for mobility and communication in ALS.
Disability and rehabilitation. Assistive technologyRecurrent Vertebrobasilar Strokes Associated With Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE).
The neurologistDramatic Response to Pramipexole in Delayed-Onset Parkinsonism from Osmotic Demyelinating Syndrome.
Tremor and other hyperkinetic movements (New York, N.Y.)A Case Report of Basilar Artery Occlusion in a Healthy 36-Year-Old Female.
CureusPrefrontal cortex transcranial direct-current stimulation putatively enhances electroencephalography classification resolution of binary responses in a minimal conscious state patient.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyStimulus modality influences session-to-session transfer of training effects in auditory and tactile streaming-based P300 brain-computer interfaces.
Scientific reportsFunctional Near-Infrared Spectroscopy in the Study of Speech and Language Impairment Across the Life Span: A Systematic Review.
American journal of speech-language pathologyChronic encephalopathy and locked-in state due to scrub typhus related CNS vasculitis.
Journal of neuroimmunologyThe current state of electrocorticography-based brain-computer interfaces.
Neurosurgical focusRecovery from prolonged disorders of consciousness: A dual-center prospective cohort study in China.
World journal of clinical casesAcute polyradiculoneuritis with locked-in syndrome in a patient with Covid-19.
Journal of neurologyHistological Confirmation of Myelinated Neural Filaments Within the Tip of the Neurotrophic Electrode After a Decade of Neural Recordings.
Frontiers in human neuroscienceDecoding overt shifts of attention in depth through pupillary and cortical frequency tagging.
Journal of neural engineeringTherapeutic Approaches in Locked-in Syndrome.
Folia medicaEffects of a Vibro-Tactile P300 Based Brain-Computer Interface on the Coma Recovery Scale-Revised in Patients With Disorders of Consciousness.
Frontiers in neuroscienceDecoding Imagined and Spoken Phrases From Non-invasive Neural (MEG) Signals.
Frontiers in neuroscienceBrain-computer interfaces for communication.
Handbook of clinical neurologyBrain-computer interfaces for consciousness assessment and communication in severely brain-injured patients.
Handbook of clinical neurologyMedullary Infarction Leading to Locked-In Syndrome Following Lumbar Puncture in a Patient with Basilar Invagination.
World neurosurgery'Without A Key': A Classroom Case Study.
Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate NeuroscienceBasilar artery thrombosis during sexual intercourse.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaElectroencephalogram based communication system for locked in state person using mentally spelled tasks with optimized network model.
Artificial intelligence in medicineOptimized artificial neural network based performance analysis of wheelchair movement for ALS patients.
Artificial intelligence in medicineDecoding Speech from Single Trial MEG Signals Using Convolutional Neural Networks and Transfer Learning.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International ConferenceToward Improving Diagnostic Strategies in Chronic Disorders of Consciousness: An Overview on the (Re-)Emergent Role of Neurophysiology.
Brain sciencesTopographic Somatosensory Imagery for Real-Time fMRI Brain-Computer Interfacing.
Frontiers in human neuroscience[Locked-in Syndrome due to Primary Brainstem Injury:A Case Report].
No shinkei geka. Neurological surgeryTranscranial direct current stimulation for a patient with locked-in syndrome.
Brain stimulationDetermining the Optimal Number of MEG Trials: A Machine Learning and Speech Decoding Perspective.
Brain informatics : international conference, BI 2018, Arlington, TX, USA, December 7-9, 2018, proceedings. International Conference on Brain Informatics (2018 : Arlington, Tex.)Cocaine as a rare cause of locked-in syndrome: a case report.
Journal of medical case reportsAn Analysis of Clinical Characteristics of Rare Bilateral Cerebral Peduncular Infarction.
Frontiers in neurologyEthics of life-sustaining treatment in locked-in syndrome: A Chinese survey.
Annals of physical and rehabilitation medicineSensorimotor ECoG Signal Features for BCI Control: A Comparison Between People With Locked-In Syndrome and Able-Bodied Controls.
Frontiers in neuroscienceSleep in the completely locked-in state (CLIS) in amyotrophic lateral sclerosis.
SleepHyperhomocysteinemia induced locked-in syndrome in a young adult due to folic acid deficiency.
Nutritional neuroscienceSmog Sign: Hazy Diffusion-weighted Imaging Restriction in Dense Axonal Tracts in the Pons on Hyperacute MRI with Remarkable Clinical Improvement After Intra-arterial Thrombectomy.
CureusBasilar Artery Occlusion: Diagnosis and Acute Treatment.
Current treatment options in neurologyDisorders of consciousness terminology: history, evolution and future directions.
Brain injuryNeuroprosthetic Speech: The Ethical Significance of Accuracy, Control and Pragmatics.
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committeesAnti-pan-neurofascin IgG3 as a marker of fulminant autoimmune neuropathy.
Neurology(R) neuroimmunology & neuroinflammationGod locked you in the room, but left a window open: A case report of spinal cord stimulation in locked-in syndrome.
Brain stimulationLocked-In Syndrome Following Cervical Manipulation by a Chiropractor: A Case Report.
Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)Rethinking the locked-in state for people with ALS.
NeurologyLeveraging Nonhuman Primate Multisensory Neurons and Circuits in Assessing Consciousness Theory.
The Journal of neuroscience : the official journal of the Society for NeuroscienceDecerebrate rigidity with preservation of consciousness in pontine hemorrhage with complete neurologic recovery.
Neurology IndiaAlpha oscillations and consciousness in completely locked-in state.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyLate recovery of responsiveness after intra-thecal baclofen pump implantation and the role of diffuse pain and severe spasticity: a case report.
Acta neurochirurgicaSingle-paradigm and hybrid brain computing interfaces and their use by disabled patients.
Journal of neural engineeringSemantic and BCI-performance in completely paralyzed patients: Possibility of language attrition in completely locked in syndrome.
Brain and languageAutomated pupillometry to detect command following in neurological patients: a proof-of-concept study.
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Advancing the science of consciousness: From ethics to clinical care.
- Large-scale training data enhances silent speech decoding with around-ear EEG.
- A visual imagery paradigm for BCI strategies using imagined flickering patterns.
- Implantable Neural Speech Decoders: Recent Advances, Future Challenges.
- Central pontine myelinolysis in diffuse large B-cell lymphoma, a case series and literature review.
- Decoding intended speech with an intracortical brain-computer interface in a person with long-standing anarthria and locked-in syndrome.
- Locked-in syndrome.
- Brainstem control of sleep, wakefulness, alertness, and consciousness.
- Brain death and the brainstem.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:2406(Orphanet)
- MONDO:0016567(MONDO)
- GARD:6919(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q794457(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
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