Siringomielia

Extracellular Vesicles for the Treatment of Syringomyelia

NCT07295067

Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia

NCT06375759

The Therapeutic Effect of Betaine in Syringomyelia

NCT06308367

The Therapeutic Effect of Thalidomide in Syringomyelia

NCT06268093

A Prospective Natural History Study of Patients With Syringomyelia

NCT01150708

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NCT07295067 · Extracellular Vesicles for the Treatment of SyringomyeliaRecrutando

PHASE1

NCT06375759 · Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis…Recrutando

NCT06308367 · The Therapeutic Effect of Betaine in SyringomyeliaRecrutando

PHASE2

NCT06268093 · The Therapeutic Effect of Thalidomide in SyringomyeliaRecrutando

PHASE2

Outros ensaios clínicos

18 ensaios clínicos encontrados, 6 ativos.

Distribuição por fase

NCT01150708 · A Prospective Natural History Study of Patients With Syringo…Ativo

NCT06011226 · Development of a Patient-reported Outcome Measure for Chiari…Em breve

NCT00004738 · Genetic Analysis of the Chiari I MalformationConcluído

NCT02669836 · Posterior Fossa Decompression With or Without Duraplasty for…Concluído

NCT05646810 · Impact of Peripheral Afferent Input on Central Neuropathic P…UNKNOWN

NCT04856839 · Clinical Outcome in Patients With Syringomyelia（COPSM）UNKNOWN

NCT04220541 · Investigation of the Effects of Exercise on Patients With Ch…Concluído

NCT02341950 · Clinical Trial of a Serious Game for Individuals With SCI/DConcluído

NCT02807142 · Efficacy Assessment of the Cell Therapy Medicine NC1 in Pati…Concluído

PHASE2

NCT00011245 · Study and Surgical Treatment of SyringomyeliaConcluído

NCT00001327 · Establishing the Physiology of SyringomyeliaConcluído

Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

1.533 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 1.533

#1

Morvan syndrome in a patient with progressing metastatic thymoma and myasthenia gravis.

BMJ case reports2026 Mar 19

Morvan syndrome (MoS) is a rare paraneoplastic syndrome that is predominantly characterised by autonomic dysfunction, peripheral nerve hyperexcitability and altered mental status. Cases in literature often describe pre-existing autoimmune diagnoses in patients with MoS, alluding to its association with systemic immune dysregulation.We report a woman presenting with hypersomnolence and fluctuating mental status consistent with MoS who had been previously diagnosed with metastatic thymoma, acetylcholine receptor-positive myasthenia gravis and multiple other chronic medical conditions. The report emphasises the importance of prompt recognition of symptoms and accurate diagnosis in rare diseases, allowing for timely initiation of the appropriate immunotherapy that ultimately led to rapid and significant clinical improvement.

#2

MRI-morphometric characterization of Chiari malformation types 0 and 1 with syringomyelia: implications for diagnosis and pathogenesis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026 Mar 13

Primary Chiari malformation type 1 (CM1) and type 0 (CM0) appear to share features of overcrowding of the posterior cranial fossa (PCF) neural elements. We carried out the present study to identify anatomical features differentiating primary Chiari malformation type 1 (CM1) from Chiari malformation type 0 (CM0) and normal subjects, and then used those anatomic features for CM1 and CM0 phenotyping and diagnosis. This study included two groups of adult patients: CM0 with syringomyelia (SM) (CM0-SM) having cerebellar tonsillar descent ≤ 2 mm below the foramen magnum (FM), CM1 with syringomyelia (CM1-SM) with tonsillar herniation (TH) > 3 mm, and normal controls. Clinical data and MRI parameters were analyzed. CM1 and CM0 associated with SM share anatomic characteristics of PCF hypoplasia, size reduction, and flattening, and share clinical findings of occipital headache and cervical central myelopathy. CM1 has more pronounced PCF hypoplasia, narrower FM CSF pathways, and more expansive and extensive syringes than CM0, while CM0 has reduced FM size. Combining two MRI morphometric markers predicted CM1 with a sensitivity of 94%, and three markers predicted CM0 with a sensitivity of 90%. In CM1 and CM0, the descent of the PCF neural structures, assessed by TH and obex descent relative to the FM, correlated with PCF flattening and FM size but not with PCF size. Four PCF morphometric markers independent of TH can accurately predict the presence of CM0 and CM1 associated with syringomyelia. The online version contains supplementary material available at 10.1007/s10072-026-08820-z.

#3

Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026 Mar 09

Chiari malformation type I (CM-I) is a neurological disorder characterized by cerebellar tonsillar herniation and is often associated with syringomyelia. Posterior fossa decompression (PFD) is the primary treatment, although the optimal extent of decompression remains a topic of debate. Intraoperative ultrasonography (IOUS) offers real-time visualization to support informed surgical decision-making. This study aimed to assess the effectiveness and safety of IOUS-guided surgery in CM-I. This systematic review followed PRISMA guidelines and searched the literature up to July 5, 2025. Studies that utilized IOUS and reported related outcomes were included. A random-effects meta-analysis was employed to pool proportions, and a meta-regression analysis was conducted to explore heterogeneity. Twenty-one non-randomized observational studies, including 1,576 patients, 54.4% of whom were female, were included. The pooled clinical improvement rate was 88% (95% CI: 81%–93%), and the syrinx improvement/resolution rate was 87% (95% CI: 77%–95%). The pooled reoperation rate was 6% (95% CI: 3%–9%), and the complication rate was 6% (95% CI: 3%–8%). Meta-regression revealed that longer disease duration, motor/sensory deficits, and duraplasty were associated with improved syrinx outcomes. IOUS-guided surgery in CM-I is linked to positive clinical and radiological improvements and low complication rates. IOUS can serve as a helpful tool for customizing decompression during CM-I surgery. Larger, prospective, multi-center studies are needed to confirm these findings. [Image: see text] The online version contains supplementary material available at 10.1007/s10072-026-08879-8.

#4

Pediatric intramedullary spinal tumors: Pathological and clinical outcomes in a 96-case single-institution cohort study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026 Feb 02

Pediatric intramedullary spinal cord tumors (PIMSCTs) seriously threaten children's growth and development. This study aims to evaluate the pathological features of PIMSCTs and analyze related factors influencing clinical outcomes. A retrospective analysis was conducted on 96 children with PIMSCT who underwent surgical treatment at our hospital from January 2015 to June 2024. Relevant clinical data were collated to comprehensively analyze clinical and pathological characteristics, and to explore factors potentially affecting prognosis and neurological function. Among the 96 included patients, the thoracic spine was the most common tumor location (n = 43, 44.8%). Most patients presented with mild neurological deficits (MMS Ⅱ) at admission. Overall survival was unrelated to tumor length but correlated with the WHO grade of the tumor. No significant difference in survival was observed between H3K27M mutant and wild-type tumors (p = 0.087), while both Ki-67 and p53 expression were significantly associated with postoperative survival. Short-term postoperative neurological function correlated with tumor length, initial symptoms, and preoperative neurological status. For long-term neurological function, influencing factors included age, WHO grade, syringomyelia, postoperative MMS, and changes in the platelet-to-lymphocyte ratio (PLR). Astrocytoma was the most prevalent pathology in this study. H3K27M mutation did not significantly affect survival in high-grade spinal astrocytoma, while high Ki-67 and p53 expression correlated with poorer prognosis. Tumor length was associated with short-term but not long-term neurological function. Long-term neurological outcomes were mainly linked to inherent tumor properties and postoperative neurological status; postoperative PLR changes may partly indicate long-term neurological function.

#5

A retrospective single-center series on the surgical management and postoperative outcomes of pediatric Chiari malformation type I. Part 1: presentation, operative management, and complications.

Journal of neurosurgery. Pediatrics2026 Jan 16

Posterior fossa decompression is the main surgical treatment for Chiari malformation type I (CM-I). The authors present findings on patient presentation, surgical methods, and postoperative complications from a large cohort of pediatric patients with the aim of utilizing this institutional experience to guide evidence-based management of pediatric CM-I. A departmental operative database was queried for patients who underwent a posterior fossa decompression for CM-I between 1992 and 2021. The charts of identified patients were reviewed. Data regarding demographics, presentation, operative details, and complications were collected. A total of 510 patients were identified. The mean patient age was 10.2 ± 5.2 years, and 57% of patients were female. The most common presenting clinical symptoms or associated signs were exertional suboccipital headaches (65%), syringomyelia (55%), and scoliosis (18%). The mean cerebellar tonsillar descent was 14.2 ± 6.4 mm below the foramen magnum. At surgery, 20% of the patients with a preoperative syrinx had documented arachnoid veils obstructing the outflow tract of the fourth ventricle. Operatively, 99% of patients underwent cervical laminectomy; of these laminectomies, 89% were C1 only. Ninety-seven percent of all patients underwent suboccipital craniectomy with expansile duraplasty (PFDD), while 3% underwent bone-only decompression (PFD). Eighty-seven percent of the patients with PFDD received tonsillopexy and/or tonsillar resection. The median postoperative hospital stay was 2 days for PFD patients and 3 days for PFDD patients (p < 0.01). Postoperative complications developed in 12% of cases, with CSF leakage (5%) and aseptic meningitis (4%) being most common. CSF leakage and aseptic meningitis were also the most common reasons for early readmission after surgery. There were no intraoperative or postoperative deaths. The authors demonstrate an institutional preference for PFDD and tonsillopexy. Exertional suboccipital pain and syringomyelia were the most common indications for surgery. Complications tended to be more common with PFDD. There was a significant difference in postoperative length of stay between patients who underwent PFD (median 2 days) versus PFDD (median 3 days). CSF leakage and aseptic meningitis were the most common reasons for readmission.

Publicações recentes

Impact of Additional Tonsillar Manipulation or Intra-articular Distraction on Syrinx Remission for Type B Basilar Invagination.

Neurosurgery2026 Apr 15

Letter: Using Artificial Intelligence to Identify Three Presenting Phenotypes of Chiari Type 1 Malformation and Syringomyelia.

Neurosurgery2026 May 1

Nursing care for a patient with syringomyelia complicated by bacterial pneumonia and severe pressure injury: a case report.

Front Med (Lausanne)2026

Extensive reconstruction of cisterna magna facilitates the outcome of adults with Chiari malformation type 1: A multicenter cohort study.

Clin Neurol Neurosurg2026 Mar 30

MRI-derived three-dimensional modelling reveals cervicothoracic subarachnoid space narrowing in syringomyelia-affected cavalier king charles spaniels.

BMC Vet Res2026 Apr 1

Ver todas no PubMed

📚 EuropePMC2.775 artigos no totalmostrando 199

Clinical Diversity in Currarino Syndrome: Insights From Monozygotic Twins and a Single-Center Retrospective Study.

Congenital anomalies

Posttraumatic syrinx resulting in syringomyelia and syringobulbia: illustrative case.

Morvan syndrome in a patient with progressing metastatic thymoma and myasthenia gravis.

BMJ case reports

Minimally Invasive Tubular Posterior Cervical Laminectomy in Medically Complex Patients: A Case Series With Clinical and Radiographic Outcomes.

Complex Type Split Cord Malformation: A Two-Center Study.

Pediatric neurosurgery

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Extradural foramen magnum decompression with multiple superficial dural incisions for Chiari I malformation: a multicenter series of 91 pediatric patients.

International journal of surgery case reports

Thoracic intramedullary spinal cord astrocytoma associated with syringomyelia: a case report of gross total resection.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

MRI-morphometric characterization of Chiari malformation types 0 and 1 with syringomyelia: implications for diagnosis and pathogenesis.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Large terminal syringomyelia associated with terminal lipoma: mid- to long-term outcomes after tethered cord release.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Therapeutic lumbar puncture as a potential treatment for symptomatic paediatric syringomyelia: A single centre cohort study.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

En-bloc posterior vault distraction including the foramen magnum for Chiari I malformation in severe syndromic craniosynostosis: First cases and literature review.

Journal of neurological surgery. Part B, Skull base

Association of Posterior Fossa Morphometric Analyses with Cerebrospinal Fluid Flow Parameters in Patients with Chiari Malformation Type 1.

Flaccid Lower Limb Paraparesis Despite Infiltration of the Spinal Cord by a Secondary Central Nervous System T-cell Non-Hodgkin Lymphoma With Syringomyelia: A Case Report.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Intraoperative ultrasonography in the surgical management of Chiari I malformation: A systematic review and meta-analysis of outcomes and applications.

Asian journal of neurosurgery

The Impact of Foramen Magnum Decompression With versus Without Duraplasty on Symptom Improvement and Syrinx Reduction in Chiari 1 Malformation Patients.

Regional anesthesia and pain medicine

Fatal arachnoiditis following accidental intradural injection of chlorhexidine: a case report and literature review.

The journal of spinal cord medicine

The efficacy of surgical management in post traumatic syringomyelia: A systematic review.

Clinical outcomes of resection of thoracic arachnoid webs: patient series.

A rare presentation of CASPR2-associated Morvan syndrome overlapping with GM1-positive AMSAN: a case report.

Frontiers in immunology

Journal of veterinary internal medicine

Development and validation of the Chiari-like malformation and syringomyelia evaluation: the CHASE questionnaire.

Journal of craniovertebral junction & spine

The effectiveness of optic nerve sheath diameter in surgical decision-making for type I Chiari malformations.

Chiari Malformation Type I: A Review of Pathophysiology, Cerebrospinal Fluid Flow Dynamics, Diagnosis, Surgical Management, and Its Relationship to Syringomyelia.

The Turkish journal of pediatrics

Hypomagnesemia as a primary clue for the diagnosis of 17q12 deletion syndrome associated with spinal syringomyelia: a case report.

Case reports in hematology

Radioresistant but Alectinib-Responsive Isolated Intramedullary ALK-Positive Histiocytosis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Pediatric intramedullary spinal tumors: Pathological and clinical outcomes in a 96-case single-institution cohort study.

Journal of pediatric orthopedics

Spinal Deformity Characteristics Associated With Intraspinal Anomalies in a Population of Presumed Adolescent Idiopathic Scoliosis (AIS).

European journal of dermatology : EJD

Recurrent neurological blisters restricted to the upper limbs: cutaneous alert of syringomyelia.

Syringomyelia in the Course of Resection of Foramen Magnum Pathology: A Case Report with an Intriguing Therapeutic Solution and Systematic Review.

Brain sciences

Sinking skin flap syndrome masquerading as Chiari malformation: failed syringomyelia treatment rescued by cranioplasty. Illustrative case.

Clinical anatomy (New York, N.Y.)

Chiari I Malformation: Review and Update of Current Treatment Options.

Role of Polysomnography in Tracheostomy Decannulation in Neuromuscular Disease: A Case Report.

Subpial cerebellar tonsillectomy for decompression of the cervicomedullary junction in children and young adults.

A retrospective single-center series on the surgical management and postoperative outcomes of pediatric Chiari malformation type I. Part 1: presentation, operative management, and complications.

A retrospective single-center series on the surgical management and postoperative outcomes of pediatric Chiari malformation type I. Part 2: symptomatic outcomes and revision surgery.

Spontaneous vocalisation as a presenting clinical sign in dogs: An association with cervical localisation and intervertebral disc disease.

The Veterinary record

A Rare Case of Posterior Fossa Decompression Performed during Pregnancy for Chiari Malformation Type I.

Posterior Fossa Decompression Versus Syringo-Subarachnoid Shunt for Chiari I-associated Syringomyelia: A Systematic Review.

Surgical outcomes in Chiari malformation type I: A quality review from a Scandinavian medium-volume neurosurgical center.

Brain & spine

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Characterization of additional MRI findings in patients with Chiari spectrum disorders: focus on Chiari 0-1.5 subtypes.

Postoperative Blindness Following Posterior Cervical Surgery: Case Reports.

Neurology India

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Chiari type 1 malformations and hypermobility spectrum disorder: clinical outcomes and the importance of the differential diagnosis.

Tremor and other hyperkinetic movements (New York, N.Y.)

Longitudinal Syringomyelia, Cervical Dystonia, and Action Tremor in Trichorhinophalangeal Syndrome Type I - A Case Report.

Pediatric triad of craniofacial fibrous dysplasia, Chiari malformation type I and syringomyelia: a case report.

Acta neurochirurgica

A comment on cohort structure in Chiari I malformation studies.

Annals of thoracic surgery short reports

Adhesive Arachnoiditis in a Patient Undergoing Lung Cancer Surgery.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Terminal myelocystocele and the chiari connection: a case-based review with a novel pathophysiological hypothesis.

A Conservative Approach to Clinical Management of Syringomyelia.

Cerebellar tonsil remodeling for Chiari I malformation with syringomyelia: cisterna magna volume expansion predicts superior symptom relief.

Tailoring the Surgical Approach to Chiari I Malformation with Intraoperative Ultrasounds: Advantages, Limitations, and Controversies.

Pediatric neurosurgery

Scoliosis associated with Chiari I malformation after posterior fossa decompression: a systematic review and meta-analysis of 380 pediatric patients.

Spine deformity

Comparison of Intraspinal Abnormalities Prevalence in Congenital Scoliosis: Is Multiple Hemivertebra Associated with Higher Risk than Single Hemivertebra?

JB & JS open access

Cohort analysis of surgically managed Chiari malformation type 1: real-world data from multi-centres.

Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

Assessment of Cerebrospinal Fluid Flow Patterns Using Time-Spatial Labeling Inversion Pulse Sequence in a Dog With Chiari-Like Malformation and Syringomyelia.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

Video-Polysomnography in Peripheral Nerve Hyperexcitability: Clues to Morvan Syndrome in Two Patients and Literature Review.

Demonstration of the importance of MRI in preoperative evaluation of adolescent idiopathic scoliosis.

Spine deformity

Outcomes of 87 small-breed dogs surgically treated for Chiari-like malformation and syringomyelia.

Veterinary surgery : VS

Cerebellar tonsil manipulation in Chiari malformation type I surgery: A systematic review and meta-analysis.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Diagnostic utility of additional spine imaging for syrinx detection in the pre-operative assessment of pediatric Chiari malformation type 1.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

The management of pediatric Chiari I malformation with concomitant hydrocephalus: a multicenter retrospective analysis.

Intraoperative Ultrasound in Brain and Spine Surgery: Current Applications, Translational Value and Future Perspectives.

NeuroSci

Early-Onset Syringomyelia: A Rare Complication of TB Meningitis.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Paediatric isolated foot drop-a rare presentation of Chiari 1 malformation with holocord syrinx (case report and the review of literature).

Journal of neurological surgery reports

Unraveling the Diagnostic Challenge of Arachnoiditis Ossificans in Association with Syringomyelia: A Review of the Literature and Two Case Reports.

Spatial transcriptomic alterations of the dorsal horn in dogs with neuropathic pain.

Pain reports

Dynamic transition from spinal arachnoid diverticulum to syringohydromyelia in a cat: Correlation between computed tomography myelography and magnetic resonance imaging.

Open veterinary journal

The Pan African medical journal

Benediction sign in a patient with intramedullary tumor and syringomyelia.

Prevalence of sleep-related breathing disorders in children with myelomeningocele and other spinal dysraphisms and risk factors.

Sleep medicine

Fluids and barriers of the CNS

A 3D non-human primate digital model for pharmacokinetic prediction of intra-cerebrospinal fluid drug neuraxial dispersion.

Annals of medicine and surgery (2012)

Chiari III malformation with ruptured encephalocele: a case report and review of literature.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Surgical failures and revision strategies in Basilar invagination: an exploratory analysis of 145 published cases.

Diagnostic and Prognostic Value of Serum Neurofilament Light Chain in Canine Spinal Cord Diseases.

Veterinary sciences

Journal of orthopaedic surgery and research

Matched analysis of traction-assisted posterior spinal correction in severe scoliosis with and without syringomyelia.

Spina bifida, diplomyelia, and Chiari-like malformation in an Aberdeen Angus calf.

BMC veterinary research

Case Report: 3D-CISS and PC-MRI in the diagnosis and surgical planning of hydrocephalus secondary to presumptive lateral aperture obstruction in a dog.

Predictive potential of radiographic characteristics on outcomes after Chiari Decompression surgery: A meta-analysis of the literature.

A Conundrum of Colliding Conditions: A Histopathological Case Report of Chiari Type III with Complete Spina Bifida Aperta.

Reports (MDPI)

Could Enlarged Sagittal Cervical Canal Diameter in Conventional Plain Lateral Radiographs Indicate the Presence of Syringomyelia? A Propensity Score Matched Study.

Clinical spine surgery

Efficacy of neurosurgical intervention in syrinx resolution in patients presenting with Chiari malformation type I and syringomyelia: a systematic review and radiological meta-analysis.

A Novel Clinical Insight Into Idiopathic Syringomyelia With Occult Arachnoid Webs: Neuropathological Features, Differential Diagnosis, and Surgical Strategy.

Neurospine

Surgical technique for executing an en bloc resection of a multilevel cervical intramedullary ependymoma: A 2D operative video.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Neuropathic Arthropathy of the Shoulder Secondary to Syringomyelia.

Journal of clinical medicine

Chiari 1 Malformation, Factors That May Influence Decision Making, and Introducing the Chiari 1 Malformation Severity Classification System.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Naked sacrococcygeal teratoma associated with dorsal meningocoele and sacrococcygeal inversion: an atypical presentation of Currarino syndrome.

Australian veterinary journal

Syringomyelia in Australian Cavalier King Charles spaniels: prevalence and changes over 16 years of magnetic resonance imaging screening.

Quality-of-Life Outcomes in Adults and Children With Chiari 1 Malformation and in Those Managed Without Surgery: A Prospective, Multicenter, Observational Study.

Spinal cord malformations's epidemiology in French children: National cross sectional study based on medico-administrative database.

Neuro-Chirurgie

Current Approach and Predictors of Clinical Outcomes in Adults With Spinal Ependymomas.

Prevalence of Neural Axis Abnormalities in Typical and Atypical Laterality Idiopathic Scoliosis: A Systematic Review and Meta-Analysis of Observational Studies.

Schweizer Archiv fur Tierheilkunde

The bregmatic fontanelle alone is an unreliable indicator of health in Pomeranian and other toy-sized dogs.

Syrinx in spontaneous intracranial hypotension treated by surgical disconnection of CSF venous fistula.

Practical neurology

Minimally Invasive Decompression for Chiari I Malformation: A Systematic Review and Meta-Analysis.

Idiopathic Syringomyelia: Diagnostic Value of Cranial Morphometric Parameters.

Brain sciences

Risk factors associated with rapid progression of scoliosis following intraspinal lesion resection in laminoplasty patients.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Favorable clinical outcomes and complications of endoscopic third ventriculostomy in Chiari Malformation Type I: A systematic review and meta-analysis.

Oxford medical case reports

Pollakiuria: a rare and unique mode of revelation of silent dorsal syringomyelia in a young man-a case report.

Subarachnoid hemorrhage secondary to Chiari 1 malformation in a patient presenting with recurrent severe headache: A case report, imaging, and anatomic considerations.

Cough syncope and central sleep apnea caused by CM1 with atlas assimilation in adult: An illustrative case.

Fourth ventricular stenting in foramen magnum decompression for type 1 Chiari malformations with syringomyelia.

Mini-open exoscopic surgery for C1 restenosis 7 years after decompression of Chiari malformation type 1 with atlas assimilation.

Follow-up of syringomyelia due to Chiari type I malformation with phase-contrast magnetic resonance imaging in a professional athlete.

Current neuropharmacology

Betaine: A Promising Natural Product for Neurological and Psychiatric Diseases.

International journal of surgery case reports

Charcot arthropathy of the shoulder joint following Arnold-Chiari malformation: A case report.

Arachnoid web-a rare but surgically effectively treatable cause of spinal cord compression and syringomyelia.

Brain & spine

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

A novel Minimally-Invasive technique for Non-Traumatic postoperative adhesive Syringomyelia.

Journal of craniovertebral junction & spine

The effect of atlantoaxial stabilization on juvenile idiopathic scoliosis involving Chiari malformation and syrinx.

Pediatric Craniovertebral Junction Anomalies: A Literature Review.

Chiari-like Malformation and Syringomyelia in Pomeranians: A Longitudinal Study.

Veterinary sciences

Journal of clinical imaging science

Partially calcified giant hemorrhagic syringomyelia and hematomyelia.

Is "routine" magnetic resonance imaging necessary in adolescent idiopathic scoliosis? A retrospective analysis in New Zealand.

Asian spine journal

Syringobulbia and Syringomyelia Associated with Intramedullary Ependymoma.

The Efficacy of Atlantoaxial Facet Joint Distraction and Fixation and Foramen Magnum Decompression for Chiari Type 1 Malformation with Basilar Invagination: A Case Report.

Resolution of tonsillar herniation and syringomyelia after resection of supratentorial large meningioma.

Brain & spine

Journal of neurology, neurosurgery, and psychiatry

Natural history of Chiari I malformation-syringomyelia: longitudinal cohort study.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Paediatric idiopathic syringomyelia - a follow-up of radiological and clinical outcomes into adulthood.

Effect of Dynamin-2 Gene Modified OECs on Functional and Molecular Neuroprotection After Spinal Cord Injury in Rats.

Neurochemical research

Chiari I malformation with syringomyelia: Exploring novel dermatological markers in pediatrics.

Pediatric Arnold-Chiari I Malformation With Syrinx Presenting With Unilateral Hand Weakness: A Case Report.

Hand (New York, N.Y.)

Journal of Brown hospital medicine

Not The Classic Waxing and Waning Multiple Sclerosis: A Case Report.

Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review.

Clinical case reports

International journal of surgery case reports

Resolution of tension pseudomeningocele complicating foramen magnum decompression for Chiari I malformation after ventriculoperitoneal shunt: A case report.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

A comparison of prone versus sitting position for the surgical treatment of Chiari malformation type I in children.

Syringomyelia Associated with Magendie's Foramen Obstruction Due to Probably Congenital Gliomesenchymal Anomaly.

The American journal of case reports

Exploring Telitacicept for Neurological Autoimmune Disorders: A Case Study on Morvan Syndrome.

Journal of pediatric surgery

Sacrococcygeal Teratomas in Currarino Syndrome: A Multicenter Review of Tumor Characteristics, Surgical Outcomes, and Recurrence.

Journal of extracellular vesicles

First-In-Human Application of Human Umbilical Cord-Derived Extracellular Vesicles in Tethered Spinal Cord Release Surgery.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Facial onset sensory-motor neuronopathy: diagnostic challenges and insights from a case report.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Effectiveness of conus lipoma surgery-a case series.

Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari - I malformation: A case report.

Radiology case reports

Clinical outcome of different surgical approaches for symptomatic Chiari malformation without syringomyelia: a 13-year retrospective study.

A Case Report of an Adverse Outcome: Development of a Dural Arteriovenous Fistula Following Foramen Magnum Decompression for Chiari Malformation.

Decompression with Intradural Dissection for the Chiari Malformation Type I: Toward Eliminating Wound Complications.

Computational and biological modeling of IGF1R inhibition for multifocal medulloblastoma.

Communications medicine

Neurologia medico-chirurgica

Dynamic Magnetic Resonance Imaging Changes in Spinal Ependymomas and Their Impact on Surgical Planning.

Adult-Onset Syringomyelia in Dandy-Walker Malformation Patients: Clinical Insights and Literature Review.

Brain sciences

Acta neurologica Taiwanica

Nasopharyngeal Carcinoma with Spinal Cord Metastasis and Secondary Syringomyelia: A Case Report.

Clinical medicine insights. Case reports

Intradural-Intramedullary Spinal Teratoma with Syrinx Formation: A Case Report.

Journal of clinical medicine

Orthopedic Manifestations of Syringomyelia: A Comprehensive Review.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

Atlantoaxial instability in Chiari formation- an analysis based on static and dynamic head imaging in 35 patients.

The impact of surgical and medical treatment on headaches in pediatric patients with Chiari malformation type I.

Adult Chiari Type I Malformation Presenting as Emergent Acute Respiratory Insufficiency: A Case Report and Literature Review.

Basilar Invagination Diagnosis, Classification, and Radiology: WFNS Spine Committee Recommendations.

Genomic analyses in Cavalier King Charles spaniels identify loci associated with clinical signs of Chiari-like malformation and Syringomyelia.

BMC veterinary research

Journal of veterinary internal medicine

Cerebrospinal Fluid Concentrations of Calcitonin Gene Related Peptide in Dogs With Chiari-Like Malformation.

Clinical phenotypes among patients with familial forms of Chiari malformation type 1.

Syringomyelia Charcot-arthropathy involving the joints of both hands.

Clinical rheumatology

Epidemiological Data, Clinical Signs, Therapy and Outcome Evaluation in Dogs with Syringomyelia of Different Etiology.

Veterinary sciences

Difference in clinical presentation and surgical outcomes in pediatric and adult patients with Chiari malformation type 1: a single center retrospective study.

Acta neurochirurgica

Successful treatment of morvan syndrome with efgartigimod: report of two cases.

Journal of neurology

Einstein (Sao Paulo, Brazil)

Moebius Syndrome associated with syringomyelia: a case report.

Substantiated degeneration of rectus capitis posterior minor muscle in Chiari malformation I based on multimodal observations: a prospective cohort study.

Journal of neurological surgery. Part A, Central European neurosurgery

Posterior Fossa Decompression Followed by Duraplasty with Arachnoid-Preserving Technique for Primary and Recurrent Adult Chiari Malformation Type-1.5: A Comparative Retrospective Study.

Surgical Strategy Analysis of Chiari Malformation With or Without Type II Basilar Invagination According to the Morphological Types of the Atlanto-Occipital Joint: A Retrospective Study of 212 Patients.

Neurospine

Animals : an open access journal from MDPI

The Effectiveness of Amitriptyline and Gabapentin in Treating Pomeranians with Chiari-like Malformation and/or Syringomyelia.

Skull Base and Craniocervical Anomalies in Syndromic Craniosynostosis.

Korean journal of family medicine

Chiari malformation type I with extensive syringomyelia presenting as progressive bilateral foot drop: a case report.

A silent malformation: Closed spinal dysraphism in a boy with urinary incontinence.

Radiology case reports

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Posterior-only hemivertebra bone-disc-bone osteotomy (BDBO) without internal fixation in a 15-day-old neonate with 18-year follow-up.

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes

Pediatric Spine Ultrasound: Comprehensive Review and Systematic Approach.

Can posterior fossa decompression alone effectively treat Chiari malformation type I patients with even severe syringes? Illustrative cases.

Rinsho shinkeigaku = Clinical neurology

[A case of amyotrophic lateral sclerosis complicated by syringomyelia associated with Chiari type I malformation].

Indian dermatology online journal

Rare Masqueraders of Pure Neuritic Leprosy: A Report of Four Cases.

Journal of Korean Neurosurgical Society

Surgical Correction for Adolescent Idiopathic Scoliosis : A Case Series of 139 Consecutive Patients Treated in Neurosurgical Department.

A new concept and surgical approach for Chiari malformation type I based on the protection and strengthening of the myodural Bridge.

Scientific reports

Acute Progressive Spinal Arachnoid Web Without the Scalpel Sign: A Case Report.

Clinical efficacy of surgery for patients with Chiari malformation type I with syringomyelia: posterior fossa decompression versus posterior fossa decompression with resection of tonsils.

Frontiers in neurology

Denervation of rectus capitis posterior minor as neglected factor in Chiari malformation type I revealed by double blinded prospective study.

Scientific reports

CT- and MRI-based volumetry for Chiari-like malformation and syringomyelia in Pomeranians.

TNF-α mediates activation of neuronal necroptotic signaling in rat with syringomyelia.

Experimental neurology

Fluids and barriers of the CNS

A review of cerebrospinal fluid circulation with respect to Chiari-like malformation and syringomyelia in brachycephalic dogs.

Journal of craniovertebral junction & spine

Atlantoaxial fixation for treatment of syringobulbia and syringomyelia: Case report and literature review.

Morphometric Evaluation of Posterior Fossa in Patients Operated Due to Chiari Malformation Type 2.

A Rare Course of Chiari Malformation With Large Syringomyelia Presenting at 54 Years Old.

Asian journal of neurosurgery

A Prospective Study of CSF Flow Dynamics Across Foramen Magnum in Adult Chiari Malformation/Syringomyelia Complex and its Clinical Correlation with Outcomes after Surgery.

A Novel Surgical Technique for Post-traumatic Syringomyelia Progressing to the Medulla Oblongata: Evidence of Upward Drainage of Central Canal Fluid Within the Spinal Cord.

Fluids and barriers of the CNS

Ependymal cilia decline and AQP4 upregulation in young adult rats with syringomyelia.

Phase-contrast magnetic resonance imaging-based predictive modelling for surgical outcomes in patients with Chiari malformation type 1 with syringomyelia: a machine learning study.

Clinical radiology

Journal of neurosurgery. Spine

A novel minimally invasive surgical technique for posttraumatic syringomyelia: subarachnoid-subarachnoid bypass.

Impact of intradural abnormalities on symptoms and clinical outcomes in Chiari malformation.

Asian journal of endoscopic surgery

Myoclonic Seizures After Endoscopic Cervical Disc Surgery: A Rare Complication or Just Coincidence?

The range of motion characteristics of atlantoaxial joints with the "sandwich" deformity: a human cadaveric biomechanical study.

Indications for Surgery and Surgical Options in Chiari Malformation: WFNS Spine Committee Recommendations.

Pediatric Chiari Malformation Management: WFNS Spine Committee Recommendations.

Maternal, Clinical, and Radiographic Outcomes: A Retrospective Analysis of Anesthesia and Delivery Modality in Chiari I Malformation.

A data driven approach for soft tissue biomarker identification linked to Chiari-like malformation and syringomyelia.

Using Artificial Intelligence to Identify Three Presenting Phenotypes of Chiari Type-1 Malformation and Syringomyelia.

Destructive arthropathy of the shoulder secondary to syringomyelia.

Joint bone spine

The spine journal : official journal of the North American Spine Society

Clinical and surgical characteristic of atlantoaxial reduction and fixation for patients with syringomyelia caused by atlantoaxial dislocation: retrospective study of 101 cases.

Which type of duraplasty is best for Chiari type I malformation surgery?

Neurosurgical focus

Journal of pharmaceutical health care and sciences

Remdesivir-induced severe hypoglycemia in an elderly man without diabetes: a case report.

Effectiveness of Cerebellar Tonsillectomy Treatment for Revision Chiari Malformation Surgery: A Series of 63 Patients.

Syringomyelia with Central Canal Enlargement Caused by Postoperative Inflammation after Surgery for Intradural Lumbar Disc Herniation.

Arnold-Chiari Malformation Type I Presenting With Bilateral Scapular Winging.

Holocord syringomyelia in 18 dogs.

Case report: Electrical impedance tomography-guided ventilator weaning in an obese patient with severe pneumonia.

Frontiers in medicine

Anesthetic Management of a Patient With Arnold Chiari Malformation and Syringomyelia During Laparoscopic Surgery With Neurologic Monitoring: A Case Report.

A&A practice

American journal of translational research

Scoliosis in adult Type 1 Chiari malformation with syringomyelia patients: from pathogenesis to treatment.

One is not like the other: health quality of life scores vary in neuromuscular EOS by diagnosis.

Spine deformity

Medical science monitor : international medical journal of experimental and clinical research

Chiari Malformation Type I and Syringomyelia: Outcomes of Arachnoid-Preserving Surgical Technique.

Incidence of idiopathic syrinx in pediatric patients diagnosed with VACTERL association.

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