Raras
Buscar doenças, sintomas, genes...
Zigomicose
ORPHA:73263CID-10 · B46.0CID-11 · 1F2CDOENÇA RARA

Qualquer infecção causada por um fungo do filo Zygomycota. A doença geralmente envolve a área rinofacial-craniana, pulmões, trato gastrointestinal, pele ou, menos comumente, outros sistemas orgânicos. Os fungos infectantes têm predileção por invadir vasos do sistema arterial, causando embolização e subsequente necrose do tecido circundante.

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Introdução

O que você precisa saber de cara

📋

Qualquer infecção causada por um fungo do filo Zygomycota. A doença geralmente envolve a área rinofacial-craniana, pulmões, trato gastrointestinal, pele ou, menos comumente, outros sistemas orgânicos. Os fungos infectantes têm predileção por invadir vasos do sistema arterial, causando embolização e subsequente necrose do tecido circundante.

Publicações científicas
1.135 artigos
Último publicado: 2026

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: B46.0
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫃
Digestivo
9 sintomas
👁️
Olhos
5 sintomas
🩸
Sangue
5 sintomas
🧬
Pele e cabelo
4 sintomas
🫁
Pulmão
4 sintomas
📏
Crescimento
3 sintomas

+ 37 sintomas em outras categorias

Características mais comuns

55%prev.
Dor
Frequente (79-30%)
55%prev.
Febre
Frequente (79-30%)
55%prev.
Tosse
Frequente (79-30%)
55%prev.
Infecção cutânea incomum
Frequente (79-30%)
55%prev.
Sinusite
Frequente (79-30%)
55%prev.
Fadiga
Frequente (79-30%)
77sintomas
Frequente (6)
Ocasional (42)
Muito raro (29)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 77 características clínicas mais associadas, ordenadas por frequência.

DorPain
Frequente (79-30%)55%
FebreFever
Frequente (79-30%)55%
TosseCough
Frequente (79-30%)55%
Infecção cutânea incomumUnusual skin infection
Frequente (79-30%)55%
SinusiteSinusitis
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico1.135PubMed
Últimos 10 anos200publicações
Pico202037 papers
Linha do tempo
2026Hoje · 2026🧪 2001Primeiro ensaio clínico📈 2020Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 21
·Pré-clínico1
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 2 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Zigomicose

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

36 ensaios clínicos encontrados.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
231 papers (10 anos)
#1

Disseminated Mucormycosis with Characteristic Gastric Ulcers and Extensive Intravascular Invasion after ABO-Incompatible Living-Donor Liver Transplantation: A Case Report.

Surgical case reports2026

Mucormycosis is a life-threatening invasive fungal infection that occurs mainly in patients who are immunocompromised. Here, we report a case of mucormycosis with characteristic gastric ulcers and severe vascular invasion after ABO-incompatible living-donor liver transplantation. A male patient in his 50s with decompensated cirrhosis due to metabolic dysfunction-associated steatohepatitis underwent an ABO-incompatible living-donor liver transplantation. Rituximab (375 mg/m2) was administered 14 days before transplantation, and tacrolimus (1 mg/day) and mycophenolate mofetil (500 mg/day) were initiated 7 days before surgery. Plasma exchange was performed the day before transplantation. Postoperatively, tacrolimus, mycophenolate mofetil, and methylprednisolone were continued as immunosuppressants, and micafungin was administered as antifungal prophylaxis. The postoperative course was complicated by sepsis due to infectious enteritis, which required broad-spectrum antibiotics. Two episodes of T cell-mediated rejection occurred, both treated with steroid pulse therapy. On POD 39, esophagogastroduodenoscopy was performed for persistent anemia and bloody drainage from the nasogastric tube. Multiple extensive gastric ulcers surrounded by dark brown mucosa were observed. Biopsy specimens revealed broad aseptate hyphae with wide-angle branching, consistent with mucormycosis. Rhizopus microsporus, the causative organism of mucormycosis, was isolated from gastric juice culture, confirming the diagnosis. Contrast-enhanced CT demonstrated poor enhancement of the gastric wall and multiple pulmonary nodules, suggesting disseminated fungal infection. Intravenous liposomal amphotericin B was initiated; however, on POD 56, the patient developed septic shock and died of multiple organ failure on POD 63. Autopsy revealed mucormycosis in the stomach, lungs, adrenal glands, thyroid gland, and kidneys. Cobblestone-like fungal masses were identified along the thoracic aortic intima, indicating extensive vascular invasion. This case represents a breakthrough mucormycosis infection that developed despite antifungal prophylaxis. The disease manifested as characteristic gastric ulcerations and extensive vascular invasion, leading to fatal outcomes despite liposomal amphotericin B therapy. Necrotic gastric ulcers and positive gastric juice cultures provide critical diagnostic clues. In highly immunosuppressed liver transplant recipients, atypical gastric findings should raise suspicion for mucormycosis, and early systemic evaluation is essential to improve otherwise poor prognoses.

#2

Conidiobolomycosis: apparent yet overlooked. A report of two cases.

BMC infectious diseases2026 Feb 16

Conidiobolomycosis is a rare, chronic subcutaneous fungal infection caused primarily by Conidiobolus coronatus and Conidiobolus incongruus. It predominantly affects immunocompetent individuals and presents as slowly progressive rhino-facial swelling. Due to its indolent nature and rarity, it is often misdiagnosed, leading to delayed treatment and potentially disfiguring outcomes. We report two successfully treated cases of conidiobolomycosis from Sri Lanka. The first patient, a 27-year-old immunocompetent male, presented with a six-month history of left-sided nasal obstruction, rhinorrhea, and gradual, painless swelling that initially affected the left nasal cavity and later extended to the left cheek, infraorbital region, and right nasal side. Histopathological examination of excision biopsy specimens revealed broad, aseptate fungal hyphae with associated necrotizing granulomatous inflammation and dense eosinophilic infiltrates. He was treated with oral itraconazole 200 mg twice daily and saturated potassium iodide solution (1 ml three times daily). Clinical symptoms completely resolved after six weeks, and therapy was continued for an additional month before cessation. The second patient, a 59-year-old previously healthy female, presented with a five-month history of progressive left-sided nasal congestion and disfiguring swelling over the nose. Clinical examination and radiological assessment revealed soft tissue thickening in the nasolabial fold extending into the nasal septum. Biopsy samples showed granulomatous inflammation with broad, sparsely septate fungal hyphae, confirmed on Grocott-Gomori methenamine silver (GMS) staining. Direct microscopy with 10% potassium hydroxide (KOH) demonstrated thin-walled, hyaline hyphae with irregular branching and few septations. She also recovered completely with itraconazole treatment. Both patients achieved complete resolution with medical management, emphasizing that early recognition and targeted antifungal therapy can lead to excellent outcomes in conidiobolomycosis. Despite its rarity, this infection should be considered in patients presenting with persistent rhino-facial swelling, especially in endemic areas. While the prognosis is generally good, prolonged therapy may be necessary, and cosmetic deformities may persist. Increased clinical awareness and timely diagnosis are essential to prevent complications and disfigurement associated with this overlooked fungal infection.

#3

Liposomal amphotericin B in the treatment of pediatric gastrointestinal basidiobolomycosis.

Journal of medical case reports2026 Feb 03

Gastrointestinal basidiobolomycosis is a rare fungal infection caused by Basidiobolus ranarum, increasingly recognized as an intestinal pathogen in children. Its clinical features closely mimic malignancy or inflammatory bowel disease, leading to frequent diagnostic delays. Although endemic in regions such as Saudi Arabia, Iran, and Oman, sporadic cases occur worldwide. Amphotericin B-liposomal remains a cornerstone therapy for invasive fungal disease, but no standardized treatment protocol for pediatric gastrointestinal basidiobolomycosis has been established. We report a 6-year-old Asian girl, born preterm with very low birth weight, who presented with persistent abdominal pain without organomegaly, alternating diarrhea and constipation, fever, and anorexia. Initial ultrasonography revealed colonic wall thickening with aneurysmal dilation at the splenic flexure. Colon biopsy confirmed Basidiobolus ranarum. The patient received intravenous liposomal amphotericin B (90 mg daily), with partial radiologic improvement but persistent symptoms, prompting exploratory laparotomy. Adhesiolysis, left hemicolectomy, and resection of jejunal and colonic masses were performed. Histopathology demonstrated dense eosinophil-rich granulomatous inflammation with multinucleated giant cells and a solitary fungal hypha, without classic Splendore-Hoeppli phenomenon, likely due to prior antifungal therapy. Postoperatively, the patient was discharged on oral itraconazole for 28 days with adjunctive cotrimoxazole. At 1-year follow-up, she remained asymptomatic with no evidence of recurrence. This case highlights the diagnostic challenges of pediatric gastrointestinal basidiobolomycosis and demonstrates successful management with liposomal amphotericin B followed by itraconazole. It underscores the ongoing gap in establishing standardized treatment and supports further prospective studies to define optimal antifungal and surgical strategies for this rare entity.

#4

Treatment of pulmonary mucormycosis: current concepts.

Expert review of anti-infective therapy2026 Jan

Pulmonary mucormycosis (PM) is a rapidly progressive angioinvasive fungal infection with high mortality. Despite therapeutic advances, optimal management remains uncertain. We review the evidence on managing PM. We emphasize aggressive host factor optimization (glycemic control, immunosuppression reduction) and outline the evidence-based antifungal strategy: liposomal amphotericin B (L-AMB) for induction, followed by oral maintenance (posaconazole or isavuconazole). We discuss critical nuances, including LAMB dosing, timing, and duration of therapy, drug interactions, and therapeutic drug monitoring. We review the role of combination antifungals, newer agents, and adjunctive modalities (inhaled antifungals, immunomodulation, bronchoscopic interventions, and iron chelation), assessing their appropriate use. The timing, indications, feasibility, and perioperative risk of surgery are discussed. We provide practical guidance for PM in special populations, including children, pregnant women, individuals with chronic liver or renal disease, and transplant recipients. Optimal care of PM requires early recognition, prompt LAMB induction with rigorous host factor optimization, multidisciplinary surgical assessment, followed by oral triazole maintenance. Combination antifungal therapy lacks definite evidence and should be reserved for severe or refractory cases. Future research priorities include prospective evaluation of treatment strategies, host-directed therapies, emerging antifungals (oral nanocrystal amphotericin, fosmanogepix, etc.), and systematic assessment of adjunctive modalities.

#5

An outbreak of ovine conidiobolomycosis in the Brazilian Amazon.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2026 Mar

Conidiobolus sp. causes conidiobolomycosis, an emerging invasive fungal disease that affects humans and animals, mainly in tropical regions. In sheep, the disease has a major economic impact. We report an outbreak of conidiobolomycosis on a sheep farm in the Brazilian Amazon, as well as give a brief review of the subject. Veterinary care was requested on a rural property on which 3 of 35 sheep had developed prostration, facial edema, and exophthalmos. Two of the sick animals died, and a third was referred to the Veterinary Hospital of the Federal University of Acre (Rio Branco, Acre, Brazil). After imaging tests, the animal was euthanized given the advanced clinical stage of the disease. The main autopsy findings were rhinosinusitis with caseous necrosis, destruction of the nasal turbinates, and pulmonary granulomas. Based on our histologic, immunologic, microbiologic, and molecular tests, the outbreak was confirmed to be caused by Conidiobolus lamprauges, a saprozoonotic agent that has not been reported previously in northern Brazil, to our knowledge.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC623 artigos no totalmostrando 199

2026

Disseminated Mucormycosis with Characteristic Gastric Ulcers and Extensive Intravascular Invasion after ABO-Incompatible Living-Donor Liver Transplantation: A Case Report.

Surgical case reports
2026

Conidiobolomycosis: apparent yet overlooked. A report of two cases.

BMC infectious diseases
2026

Liposomal amphotericin B in the treatment of pediatric gastrointestinal basidiobolomycosis.

Journal of medical case reports
2026

Treatment of pulmonary mucormycosis: current concepts.

Expert review of anti-infective therapy
2026

An outbreak of ovine conidiobolomycosis in the Brazilian Amazon.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2025

Rhino-Orbital-Cerebral Mucormycosis Complicated by Vision Loss in a Patient with Uncontrolled Diabetes: A Case Report.

Microorganisms
2025

Novel use of hyperbaric oxygen treatment for treatment-resistant disseminated Saksenaea and Fusarium in a patient on extracorporeal membrane oxygenation (ECMO): a case report.

Diving and hyperbaric medicine
2025

Rhino-orbital conidiobolomycosis in non-endemic Settings. A diagnostic and therapeutic challenge.

Travel medicine and infectious disease
2025

COVID-19-Associated Mucormycosis Mimicking Odontogenic Pain: A Report of Three Cases.

Case reports in dentistry
2025

Plasma cell-free DNA PCR for diagnosing mucormycosis: are we there yet?

Journal of clinical microbiology
2025

Sensitivity and Specificity of Polymerase Chain Reaction in Blood and Bronchoalveolar Lavage Samples for Mucormycosis: A Bayesian Diagnostic Test Accuracy Meta-Analysis.

Mycopathologia
2025

Pediatric gastrointestinal basidiobolomycosis: descriptive bicenteric retrospective study.

Scientific reports
2025

An Unusual Case of Chronic Delimited Rhinosinusal Mucormycosis With Secondary Cutaneous Involvement in a Patient With Ataxia-Telangiectasia Syndrome.

Cureus
2025

Subcutaneous mycoses - The hidden mould, a case series.

Tropical doctor
2025

Single-center retrospective study on Basidiobolomycosis: Characteristics, management, and outcomes.

Journal of infection and public health
2025

A Global Analysis of Cases of Mucormycosis Recorded in the European Confederation of Medical Mycology / International Society for Human and Animal Mycology (ECMM / ISHAM) Zygomyco.net Registry from 2009 to 2022.

Mycopathologia
2025

A fatal post-COVID-19 sino-orbital mucormycosis in an adult patient with diabetes mellitus: a case report and review of the literature.

Journal of infection in developing countries
2025

Subcutaneous Basidiobolomycosis Masquerading as Cellulitis on the Forearm of an Elderly Woman.

The American journal of tropical medicine and hygiene
2025

Development and evaluation of real-time recombinase polymerase amplification assay for fast identification of Rhizopus arrhizus.

Indian journal of medical microbiology
2025

Violaceous Nodules on the Left Forearm of an Immunosuppressed Patient Following Heart Transplantation for Cardiac Amyloidosis.

Dermatopathology (Basel, Switzerland)
2025

Entomophthoromycosis with Intraorbital and Intracranial Extension-A Rare Case Report.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
2025

Acute Necrotizing Fasciitis Caused by Rhizopus Infection in a Patient with Diabetes and Pulmonary Tuberculosis: A Case Report.

Infection and drug resistance
2025

The Importance of MRI in the Early Diagnosis of Acute Invasive Fungal Rhinosinusitis.

Diagnostics (Basel, Switzerland)
2025

Mucormycosis in a child with acute lymphoblastic leukemia: Case report.

Archivos argentinos de pediatria
2024

Mucormycosis after liver transplant: Case series and literature review.

Medical mycology case reports
2024

Unusual Presentation of Conidiobolomycosis.

The Journal of the Association of Physicians of India
2025

Successful Management of Rhinofacial Conidiobolus coronatus Infection with Itraconazole Monotherapy.

The American journal of tropical medicine and hygiene
2024

Fatal Mucormycosis in a Diabetic Patient: A Case Report and Review of Diagnostic Challenges.

Cureus
2024

Pediatric Basidiobolomycosis: An Uncommon and Misdiagnosed Entity.

Indian dermatology online journal
2024

Case report: Localized coloproctitis caused by novel Basidiobolus arizonensis in a dog.

Frontiers in veterinary science
2025

Role of Posaconazole Drug in the Treatment of Invasive Fungal Disease: A Review.

Infectious disorders drug targets
2024

Rhinocerebral mucormycosis: A clinicopathological analysis of COVID-19-associated mucormycosis.

Journal of family medicine and primary care
2024

Epidemiology and prognostic factors of mucormycosis in France (2012-2022): a cross-sectional study nested in a prospective surveillance programme.

The Lancet regional health. Europe
2024

Navigating treatment for basidiobolomycosis: a qualitative review of 24 cases.

BMC infectious diseases
2024

Successful Treatment of Sternal Osteomyelitis and Mediastinitis Caused by Rhizopus Following Cardiac Surgery.

Cureus
2024

Primary renal mucormycosis in a type 2 diabetic patient: A case report from Syria.

Heliyon
2025

Unveiling the Uncommon: Gastrointestinal Basidiobolomycosis of the Colon and its Distinctive Splendore-Hoeppli Phenomenon.

International journal of surgical pathology
2024

Corona-Associated Mucormycosis: Case Series Reports and Review of the Literature.

Journal of fungi (Basel, Switzerland)
2024

The effect of infection with the entomopathogenic fungus Conidiobolus coronatus (Entomopthorales) on eighteen cytokine-like proteins in Galleria mellonella (Lepidoptera) larvae.

Frontiers in immunology
2024

Prevalence of co-existent COVID-19-associated pulmonary aspergillosis (CAPA) and its impact on early mortality in patients with COVID-19-associated pulmonary mucormycosis (CAPM).

Mycoses
2024

Cutaneous mucormycosis with suspected dissemination in a patient with metastatic adrenocortical carcinoma.

Medical mycology case reports
2024

A rare case of mucormycosis in a diabetic patient: diagnostic challenges and clinical management of mucormycosis hand infection.

Case reports in plastic surgery &amp; hand surgery
2024

Masquerading fungal bowel mass in an adolescent: a clinicopathological challenge.

BMJ case reports
2023

[Conidiobolomycosis (rhinofacial entomophthoromycosis) in Gabon. About of one case].

Medecine tropicale et sante internationale
2024

From Spores to Solutions: A Comprehensive Narrative Review on Mucormycosis.

Diagnostics (Basel, Switzerland)
2024

Disseminated Basidiobolomycosis Caused by Basidiobolus omanensis in a Child with Acute Lymphoblastic Leukemia (ALL). Case Report and Literature Review.

Mycopathologia
2024

Immune and metabolic perturbations in COVID-19-associated pulmonary mucormycosis: A transcriptome analysis of innate immune cells.

Mycoses
2024

Case Report: Gastrointestinal Basidiobolomycosis in a Young Girl with Cystic Fibrosis and Celiac Disease.

The American journal of tropical medicine and hygiene
2023

Rise of mucormycosis during the COVID-19 pandemic and the challenges faced.

Current medical mycology
2023

Emergence of Rhino-Orbito-Cerebral Mucormycosis in Peru: Impact of the COVID-19 Pandemic.

Cureus
2024

Invasive Eumycotic mycetoma of the nasal septum in a post-dialysis patient: A case report.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2024

ThinPrep liquid-based cytologic diagnosis of hepatic entomophthoromycosis (basidiobolomycosis) with Splendore-Hoeppli phenomenon.

Diagnostic cytopathology
2024

Unusual orbital mucormycosis due to pecking injury: clinical characteristics and outcomes of four immunocompetent pediatric patients.

Orbit (Amsterdam, Netherlands)
2023

Subcutaneous entomophthoromycosis masquerading as soft tissue neoplasm in breastfeeding mother.

BMJ case reports
2023

Ibrutinib and tracheal mucormycosis: A case report and systematic review of literature.

Journal de mycologie medicale
2023

Mucormycosis in Human Immunodeficiency Virus-Infected Individuals: A Systematic Review of Case Reports.

Mycopathologia
2023

Rhinofacial Conidiobolomycosis - A rare fungal infection of tropics.

Tropical doctor
2023

Epidemiology of COVID-19-Associated Mucormycosis.

Current fungal infection reports
2023

Part 1: Mucormycosis: prevalence, risk factors, clinical features, and diagnosis.

Expert review of anti-infective therapy
2023

Hyphae, pseudohyphae, yeasts, spherules, spores, and more: A review on the morphology and pathology of fungal and oomycete infections in the skin of domestic animals.

Veterinary pathology
2023

COVID-related mucormycosis mimicking dental infection.

Oral and maxillofacial surgery cases
2023

Risk factors for pulmonary mucormycosis in subjects with diabetes mellitus-A case-control study.

Mycoses
2023

Cutaneous zygomycosis: a poor prognostic indicator in burns patients.

ANZ journal of surgery
2023

Epidemiology of Mucormycosis in Greece; Results from a Nationwide Prospective Survey and Published Case Reports.

Journal of fungi (Basel, Switzerland)
2023

Treatment of pulmonary mucormycosis with adjunctive nebulized amphotericin B (MUCONAB trial): Results of an open-label randomized controlled trial.

Mycoses
2023

Post-COVID mucormycosis in presentation of periodontal abscess.

Journal of family medicine and primary care
2022

COVID-19 associated mucormycosis: A case report in Pakistan and a review of 144 cases.

JPMA. The Journal of the Pakistan Medical Association
2022

Case series of invasive lung infections by Aspergillus species and zygomycosis among post COVID-19 and post-transplant individuals.

Journal of family medicine and primary care
2023

Unmasking the Deadly Fungus: A Case Report of Rhino-Orbital-Cerebral Mucormycosis in a Diabetic Patient With Unusual Presentation.

Cureus
2023

The gastrointestinal basidiobolomycosis, a rare entity: Case report and review of literature.

JPMA. The Journal of the Pakistan Medical Association
2023

Subcutaneous zygomycosis in an immunocompetent patient caused by Basidiobolus ranarum.

BMJ case reports
2023

Multicenter Case-Control Study of COVID-19-Associated Mucormycosis Outbreak, India.

Emerging infectious diseases
2023

Mucormycosis in Post Novel Corona Virus Patients: An Institutional Experience.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
2022

A Comprehensive in vitro and in silico Assessment on Inhibition of CYP51B and Ergosterol Biosynthesis by Eugenol in Rhizopus oryzae.

Current microbiology
2022

Efficacy of Two-phase Treatment Regimen for Rhino-facial Entomophthoromycosis: Our Experience and Review of Literature.

Oman medical journal
2022

Subcutaneous entomophthoromycosis in an immunocompetent individual: a localised forearm swelling.

BMJ case reports
2022

An old confusion: Entomophthoromycosis versus mucormycosis and their main differences.

Frontiers in microbiology
2022

Site-Based Comparative Analysis of Sample Collection Through Direct Biopsy and Nasal Swabs for Early Diagnosis of Post-COVID Rhinomaxillary Fungal Infection Using Potassium Hydroxide Mounting: A Retrospective Cohort Study.

Journal of maxillofacial and oral surgery
2022

Current treatments against mucormycosis and future directions.

PLoS pathogens
2022

Profile of Secondary Bacterial and Fungal Infections in Hospitalized COVID-19 Patients in a Tertiary Care Centre.

Infection and drug resistance
2023

Rhinoentomophthoromycosis: A cause of central face disfigurement.

International journal of dermatology
2022

Colonic basidiobolomycosis in a patient with systemic lupus erythematosus (SLE).

BMC infectious diseases
2022

A Surgical Approach in the Management of Mucormycosis in Trauma Patients.

Journal of pharmacy &amp; bioallied sciences
2022

The impact of mucormycosis (black fungus) on SARS-CoV-2-infected patients: at a glance.

Environmental science and pollution research international
2022

Insect cuticular compounds affect Conidiobolus coronatus (Entomopthorales) sporulation and the activity of enzymes involved in fungal infection.

Scientific reports
2022

Clinical characteristics and outcome of mucormycosis: A multi-center retrospective analysis in Saudi Arabia over 11 years.

IJID regions
2022

Cultivable Skin Mycobiota of Healthy and Diseased Blind Cave Salamander (Proteus anguinus).

Frontiers in microbiology
2022

Pediatric intussusception due to basidiobolomycosis: a case report and literature review.

BMC pediatrics
2022

Disseminated mucormycosis: An unusual case of ascites with bone marrow invasion.

IDCases
2023

Mucormycosis following burn injuries: A systematic review.

Burns : journal of the International Society for Burn Injuries
2022

Rhinofacial entomophthoramycosis: an uncommon infection of the subcutaneous tissue.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2022

Serum glucose-regulated protein 78 (GRP78) levels in COVID-19-associated mucormycosis: results of a case-control study.

Mycopathologia
2022

Could cattle dung burning have contributed to the epidemic of COVID-19-associated mucormycosis in India? Results of an experimental aero-mycological study.

Mycoses
2022

Targeted Delivery of Antifungal Liposomes to Rhizopus delemar.

Journal of fungi (Basel, Switzerland)
2022

Intestinal basidiobolomycosis in a patient with idiopathic CD4 lymphocytopenia.

Journal de mycologie medicale
2022

Cutaneous Mucormycosis in an Immunocompetent Child following a Minor Skin Trauma.

Case reports in surgery
2022

A Very Rare Basidiobolomycosis Case Presented with Cecal Perforation and Concomitant Hepatic Involvement in an Elderly Male Patient: A Case Study.

International journal of environmental research and public health
2022

Treatment and economic burden of mucormycosis in China: Case report review and burden estimation.

Journal of clinical pharmacy and therapeutics
2021

Post coronavirus disease mucormycosis involving the mandible: A case report with brief note on literature.

Journal of oral and maxillofacial pathology : JOMFP
2022

Global Cutaneous Mucormycosis: A Systematic Review.

Journal of fungi (Basel, Switzerland)
2022

Isolated Cerebral Mucormycosis Caused by Lichtheimia Species in a Polytrauma Patient.

Diagnostics (Basel, Switzerland)
2022

Characterizing patients with rare mucormycosis infections using real-world data.

BMC infectious diseases
2022

Mucormycosis: The hidden and forgotten disease.

Journal of applied microbiology
2022

Community-acquired fungal pyelonephritis with renal infarction and gangrene of the colon: an uncommon diagnosis.

BMJ case reports
2021

Therapeutic innovation for multi-resistant candidemics: Synergy of isavuconazole and caspofungin association.

Hematology reports
2021

Entomophthoramycosis: An unusual cause of facial disfigurement.

Drug discoveries &amp; therapeutics
2021

[A Case of Fungalemia that Detected the Mucor circinelloides by Versa TREK].

Rinsho Biseibutsu Jinsoku Shindan Kenkyukai shi = JARMAM : Journal of the Association for Rapid Method and Automation in Microbiology
2022

Increasing Incidence of mucormycosis in Spanish inpatients from 1997 to 2018.

Mycoses
2022

Pediatric case of conidiobolomycosis: A rare entity.

Pediatric dermatology
2021

Gastric mucormycosis with splenic invasion a rare abdominal complication of COVID-19 pneumonia.

Journal of clinical imaging science
2021

Identifying Mucormycosis Severity in Indian COVID-19 Patients: A Nano-Based Diagnosis and the Necessity for Critical Therapeutic Intervention.

Antibiotics (Basel, Switzerland)
2021

Diagnosis of the misdiagnosed: Mucormycosis depicting periodontitis.

Journal of Indian Society of Periodontology
2022

Black fungus immunosuppressive epidemic with Covid-19 associated mucormycosis (zygomycosis): a clinical and diagnostic perspective from India.

Immunogenetics
2021

Rising concerns of Mucormycosis (Zygomycosis) among COVID-19 patients; an analysis and review based on case reports in literature.

Acta bio-medica : Atenei Parmensis
2021

Mucormycosis-unusual cause of lower GI bleeding: A rare case report.

International journal of surgery case reports
2021

Is there an association between zinc and COVID-19-associated mucormycosis? Results of an experimental and clinical study.

Mycoses
2022

Coronavirus Disease 2019-Associated Mucormycosis: Risk Factors and Mechanisms of Disease.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2021

Challenges in the diagnosis of pulmonary mucormycosis in a diabetic with a review of literature.

Respiratory medicine case reports
2021

Isolation of Rhizopus microsporus and Lichtheimia corymbifera from tracheal aspirates of two immunocompetent critically ill patients with COVID-19.

Medical mycology case reports
2021

Post-Covid alliance-mucormycosis, a fatal sequel to the pandemic in India.

Saudi journal of biological sciences
2021

Mucormycosis and COVID-19 an epidemic in a pandemic?

Nepal journal of epidemiology
2021

Pulmonary Mucormycosis: An Interesting Case of Rhizopus Mucormycosis.

Cureus
2021

Imaging features of perineural and perivascular spread in rapidly progressive rhino-orbital-cerebral mucormycosis: A case report and brief review of the literature.

Surgical neurology international
2022

An unusual presentation of unilateral lower limb gigantism in a case of subcutaneous entomophthoromycosis.

International journal of dermatology
2021

Fatal necrotising cutaneous mucormycosis due to novel Saksenaea species: a case study.

Journal of wound care
2021

Thoracic conidiobolomycosis: Invasive or allergic?

The journal of allergy and clinical immunology. In practice
2021

Rhino-orbital Entomophthoromycosis.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2021

A Comparative Analysis of Mucormycosis in Immunosuppressed Hosts Including Patients with Uncontrolled Diabetes in the Southwest United States.

The American journal of medicine
2021

Basidiobolomycosis: Case Report and Literature Overview.

Indian dermatology online journal
2021

Rhinofacial conidiobolomycosis: Clinical and microbiological characterisation and shift in the management of a rare disease.

Mycoses
2021

A rare case of condiobolomycosis due to Conidiobolus coronatus presenting with dysphagia.

Indian journal of medical microbiology
2021

Mucormycosis after Coronavirus disease 2019 infection in a heart transplant recipient - Case report and review of literature.

Journal de mycologie medicale
2021

Role of flexible bronchoscopy in the diagnosis of invasive fungal infections.

Mycoses
2021

Mucormycosis in a pediatric population: a review of 20 cases from southern Turkey.

The Turkish journal of pediatrics
2021

Refractory thoracic conidiobolomycosis treated with mepolizumab immunotherapy.

The journal of allergy and clinical immunology. In practice
2021

Coronavirus Disease (Covid-19) Associated Mucormycosis (CAM): Case Report and Systematic Review of Literature.

Mycopathologia
2021

Fatal Cutaneous Zygomycosis caused by Saksaenea Vasiformis.

The Journal of the Association of Physicians of India
2020

Disseminated and ulcerative basidiobolomycosis simulating a Buruli ulcer in an immunocompetent girl in Southern Benin.

The Pan African medical journal
2021

Incidence, predisposing conditions and outcomes of cutaneous mucormycosis: A national database study.

Mycoses
2021

Gastrointestinal Zygomycosis in a Preterm Neonate Associated With Contaminated Probiotics.

The Pediatric infectious disease journal
2021

Has the mortality from pulmonary mucormycosis changed over time? A systematic review and meta-analysis.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2020

A rare case of colon obstruction due to gastrointestinal basidiobolomycosis in a 36-year-old woman.

International journal of surgery case reports
2020

Molecular epidemiology of zygomycosis and their related factors in tertiary referral centers in southern Iran.

Journal of infection in developing countries
2020

The Postmortem Features of Mucormycosis.

Academic forensic pathology
2020

Pulmonary mucormycosis: A case report.

IDCases
2020

Mucormycosis in the Jaw: A Report of 2 Cases and Literature Review.

Oral health &amp; preventive dentistry
2020

Rare and Fatal Gastrointestinal Mucormycosis (Zygomycosis) in a COVID-19 Patient: A Case Report.

Clinical endoscopy
2020

Entomophthoromycosis in a child: Delayed diagnosis and extensive involvement.

Indian journal of pathology &amp; microbiology
2020

Epidemiology and Diagnosis of Mucormycosis: An Update.

Journal of fungi (Basel, Switzerland)
2020

Ulcerated Thigh Lesions in a Patient With Acute Myeloid Leukemia: Answer.

The American Journal of dermatopathology
2020

Rhino-cerebral and cutaneous zygomycosis: An increasingly emerging life-threating infection.

Dermatologic therapy
2020

A treated case of rhinocerebral zygomycosis with aspergillosis: a case report from India.

Access microbiology
2020

Host Immune Defense upon Fungal Infections with Mucorales: Pathogen-Immune Cell Interactions as Drivers of Inflammatory Responses.

Journal of fungi (Basel, Switzerland)
2020

Conidiobolomycosis, cryptococcosis, and aspergillosis in sheep and goats: a review.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2021

Gastrointestinal Basidiobolomycosis: A Mimic of Lymphoma.

The Journal of pediatrics
2020

Invasive Colonic Mucormycosis in an Immunocompromised Postliver Transplant Patient.

ACG case reports journal
2020

Rhino-orbito-cerebral mucormycosis in patients with uncontrolled diabetes: A case series.

International journal of surgery case reports
2021

An Infant with Acute Bloody Diarrhea and Gastrointestinal Basidiobolomycosis: An Unusual Presentation of a Rare Disease.

Journal of tropical pediatrics
2020

Rhinofacial entomophthoramycosis case series, the unusual cause of facial swelling.

Annals of medicine and surgery (2012)
2020

Conidiobolus pachyzygosporus invasive pulmonary infection in a patient with acute myeloid leukemia: case report and review of the literature.

BMC infectious diseases
2020

Colorectal basidiobolomycosis in a dog.

Journal of veterinary internal medicine
2020

Nasal Mucormycosis: Our experience with 24 cases.

Otolaryngologia polska = The Polish otolaryngology
2020

Detection of circulating fungal DNA by polymerase chain reaction in a fatal case of Cunninghamella bertholletiae infection.

IDCases
2020

Answer to June 2020 Photo Quiz.

Journal of clinical microbiology
2020

Evolutionary relationships among Massospora spp. (Entomophthorales), obligate pathogens of cicadas.

Mycologia
2020

Ocular basidiobolomycosis - Rare presentation: A case report.

Indian journal of pathology &amp; microbiology
2021

Rhinofacial Conidiobolomycosis: A Case Series and Review of the Literature.

Ear, nose, &amp; throat journal
2020

Systemic and Gastrohepatic Mucormycosis in Dogs.

Journal of comparative pathology
2020

Superficial Cutaneous Zygomycosis Presenting as Resistant Intertrigo: A Case Report.

Open forum infectious diseases
2020

Clinical Spectrum, Diagnosis and Outcome of Rare Fungal Infections in Patients with Hematological Malignancies: Experience of 15-Year Period from a Single Tertiary Medical Center.

Mycopathologia
2020

[Invasive fungal brain abscess: a case report].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
2019

Clinical features of pulmonary mucormycosis in patients with different immune status.

Journal of thoracic disease
2020

Heat shock proteins (HSP 90, 70, 60, and 27) in Galleria mellonella (Lepidoptera) hemolymph are affected by infection with Conidiobolus coronatus (Entomophthorales).

PloS one
2020

Invasive Basidiobolomycosis Presenting as Retroperitoneal Fibrosis: A Case Report.

International journal of environmental research and public health
2020

Quantifying guideline adherence in mucormycosis management using the EQUAL score.

Mycoses
2020

Mucormycosis in lung transplant recipients: A systematic review of the literature and a case series.

Clinical transplantation
2020

A multicentre observational study on the epidemiology, risk factors, management and outcomes of mucormycosis in India.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2019

Fungal artillery of zombie flies: infectious spore dispersal using a soft water cannon.

Journal of the Royal Society, Interface
2020

Rare indolent zygomycosis caused by subcutaneous Saksenaea vasiformis infection.

The Australasian journal of dermatology
2019

Antifungals in a case of basidiobolomycosis: role and limitations.

BMJ case reports
2019

Zygomycosis of the Scalp Caused by Rhizopus oryzae Presenting as Kerion in an Immunocompetent Child.

Indian journal of dermatology
2019

Intracranial fungal granuloma: a single-institute study of 90 cases over 18 years.

Neurosurgical focus
2019

Mucormycosis of the Central Nervous System.

Journal of fungi (Basel, Switzerland)
2019

Successful treatment of rhinoorbital mucormycosis due to Rhizopus arrhizus with liposomal amphotericin B, posaconazole and surgical debridement in a child with neuroblastoma.

Medical mycology case reports
2020

Transdiaphragmatic Mucormycosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2019

Pediatric Mucormycosis: A 10-Year Systematic Review of Reported Cases and Review of the Literature.

Journal of the Pediatric Infectious Diseases Society
2020

Basidiobolus haptosporus-like fungus as a causal agent of gastrointestinal basidiobolomycosis.

Medical mycology
2019

Mould-reactive T cells for the diagnosis of invasive mould infection-A prospective study.

Mycoses
2019

Gastrointestinal basidiobolomycosis in a patient suffering from duodenal ulcer with perforation: First case report from Italy.

The new microbiologica
2018

A Rhinofacial Conidiobolus coronatus Fungal Infection Presenting as an Intranasal Tumour.

Sultan Qaboos University medical journal
2019

Basidiobolomycosis - Miss Me; It Hurts You.

The Journal of the Association of Physicians of India
2019

Sources of microbial oils with emphasis to Mortierella (Umbelopsis) isabellina fungus.

World journal of microbiology &amp; biotechnology
2019

Gastrointestinal pythiosis with concurrent presumptive gastrointestinal basidiobolomycosis in a Boxer dog.

Veterinary clinical pathology
2020

Fatal renal mucormycosis with Apophysomyces elegans in an apparently healthy male.

The aging male : the official journal of the International Society for the Study of the Aging Male
2019

Posaconazole salvage therapy: The Posifi study.

Mycoses
2019

An instance of excellent response of subcutaneous zygomycosis to itraconazole monotherapy.

Medical mycology case reports
2019

Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors.

Medical mycology
2018

Pulmonary Mucormycosis (Zygomycosis) Presenting as an Infective Exacerbation of Chronic Obstructive Pulmonary Disease.

European journal of case reports in internal medicine
2019

Diet influences the bacterial and free fatty acid profiles of the cuticle of Galleria mellonella larvae.

PloS one
Ver todos os 623 no EuropePMC

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Disseminated Mucormycosis with Characteristic Gastric Ulcers and Extensive Intravascular Invasion after ABO-Incompatible Living-Donor Liver Transplantation: A Case Report.
    Surgical case reports· 2026· PMID 41836273mais citado
  2. Conidiobolomycosis: apparent yet overlooked. A report of two cases.
    BMC infectious diseases· 2026· PMID 41699503mais citado
  3. Liposomal amphotericin B in the treatment of pediatric gastrointestinal basidiobolomycosis.
    Journal of medical case reports· 2026· PMID 41634777mais citado
  4. Treatment of pulmonary mucormycosis: current concepts.
    Expert review of anti-infective therapy· 2026· PMID 41575183mais citado
  5. An outbreak of ovine conidiobolomycosis in the Brazilian Amazon.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc· 2026· PMID 41501631mais citado
  6. Rhino-Orbital-Cerebral Mucormycosis Complicated by Vision Loss in a Patient with Uncontrolled Diabetes: A Case Report.
    Microorganisms· 2025· PMID 41471899recente
  7. Novel use of hyperbaric oxygen treatment for treatment-resistant disseminated Saksenaea and Fusarium in a patient on extracorporeal membrane oxygenation (ECMO): a case report.
    Diving Hyperb Med· 2025· PMID 41364853recente
  8. COVID-19-Associated Mucormycosis Mimicking Odontogenic Pain: A Report of Three Cases.
    Case Rep Dent· 2025· PMID 41140942recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:73263(Orphanet)
  2. MONDO:0019136(MONDO)
  3. GARD:10224(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q6931254(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Zigomicose
Compêndio · Raras BR

Zigomicose

ORPHA:73263 · MONDO:0019136
Prevalência
Unknown
Herança
Not applicable
CID-10
B46.0 · Mucormicose pulmonar
CID-11
Início
All ages
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0026718
Repurposing
6 candidatos
flutrimazolesterol demethylase inhibitor
methylprednisoloneglucocorticoid receptor agonist
methylprednisolone-sodium-succinatemicrotubule inhibitor|tubulin polymerization inhibitor
+3 outros
EuropePMC
Wikidata
Wikipedia
Papers 10a
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