Uma febre hemorrágica viral causada pelo vírus Ebola, transmitida pelo contato com animais ou pessoas infectadas. É caracterizada por febre alta, sangramentos inexplicáveis e uma alta taxa de mortalidade.
Introdução
O que você precisa saber de cara
Uma febre hemorrágica viral causada pelo vírus Ebola, transmitida pelo contato com animais ou pessoas infectadas. É caracterizada por febre alta, sangramentos inexplicáveis e uma alta taxa de mortalidade.
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<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
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Os sintomas variam de pessoa para pessoa. Abaixo estão as 30 características clínicas mais associadas, ordenadas por frequência.
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Os sinais que médicos procuram e os exames que confirmam
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Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Febre hemorrágica do Ebola
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125 ensaios clínicos encontrados.
Publicações mais relevantes
Progressive Development of a New Tool for Rapid Thematic Analysis of Community Perceptions and Concerns During Health Emergencies.
Rapid analysis of community needs, perspectives, and concerns during global health emergencies is essential but technically challenging. In the past, emergency responders have struggled to listen to and engage affected communities because of perceptions about anticipated costs and time delays in receiving actionable results. The U.S. Centers for Disease Control and Prevention Excel Tool for Thematic Analysis was developed over 5 years of assisting with emergency responses for Ebola, COVID-19, Sudan Ebolavirus, mpox, and the Ukraine crisis. Beginning with a simple Excel spreadsheet for coding Ebola-related community feedback, we continued to add new features as needs arose, such as preloaded epidemic and health emergency coding schemes, preprogrammed results tables, step-by-step thematic analysis instruction, YouTube training videos, and planning and communication tools for effective use of the results. The tool is a customized Excel workbook for qualitative text coding and thematic analysis that enables the user to code and derive key themes from texts, such as interview and focus group transcripts, notes, surveys with open-ended questions, and social media comments. We review the 10 programmed worksheets for planning, cataloguing, coding, and thematically analyzing any kind of text data. The strategies for rapid community feedback analysis during health emergencies are a special application of qualitative analysis methodology to the health emergency setting, enabling a deep reading and transparent and defensible interpretation of the text. Skills learned while using the tool are easily transferable to analyses using licensed software or fully manual methods. The tool offers a step-by-step guide for anyone to analyze text data to answer a relevant question in or outside the context of emergencies.
Introducing a hybrid intrusion detection method for IoT-cloud environments based on ResNeXt and improved Ebola optimization search algorithm.
With the advent of IoT and its immense possibilities through cloud randomization, connectivity has matured almost out of proportion; yet this factor has equally opened various attack surfaces thereby rendering IoT-cloud environments vulnerable to multiple attacks. To address the issue, we introduce a versatile approach for hybrid intrusion diagnosis made possible through ResNeXt, a DCNN architecture noted for high efficiency and scalability in extracting features, and the Improved Ebola Optimization Search Algorithm (IEOSA), a novel metaheuristic optimizer fashioned after the spread dynamics of the Ebola virus, yet enhanced to offer speed and reliability in search performance. The proposed approach uses the comprehensive feature extraction ability of ResNeXt combined with the improved searching efficiency of the IEOSA to provide a superior method for the detection of anomalies and intrusions in an IoT-cloud environment. The network attained a detection accuracy of 98.3% and above 97% for recall, F1 score, and precision on standard datasets, including CICIDS 2017 and NSL-KDD. The hybrid framework enhances the performance of traditional and even a few deep-learning techniques, to provide a more secure IoT-cloud ecosystem. The results highlight the opportunity for integrating deep learning with a robust metaheuristic optimization approach for better efficiency and effectiveness in intrusion detection within digital infrastructures.
Enhancing cyberthreat defense mechanisms using ensemble of representation learning with binary Ebola optimization search in internet of things environment.
In the present digital era, malware defences and attacks are becoming more difficult, creating a progressing cyberthreat landscape. With the fast development in technology, cyberthreats have shown improved intricacy and potency that frequently exceed the abilities of conventional defence systems. The Internet of Things (IoT) is a technical development that allows machine-to-machine and human-to-human interaction for essential data exchange. The IoT provides numerous advantages but also builds several problems. Exposures in IoT methods are problematic and main to devices enduring various threats, with the danger of denial of service (DoS) and security challenges like privacy, confidentiality, and obtainability to assault. This manuscript proposes a cyberthreat defence mechanism using a Binary Ebola Optimization Search Algorithm and Ensemble Models (CDM-BEOSAEM) method. The main intention of the CDM-BEOSAEM method is to enhance the cyberattack detection method in an IoT environment. Initially, the min-max normalization is applied in the data normalization stage to convert input data into a beneficial format. Furthermore, the binary ebola optimization search algorithm (BEOSA) model recognizes the most appropriate features in the feature selection (FS) process. For the classification of cyberthreat defence, the proposed CDM-BEOSAEM model utilizes an ensemble of bidirectional gated recurrent unit (BiGRU), auto-encoders (AE), and graph convolutional network (GCN) techniques. Finally, the hyperparameter selection of ensemble models is performed by implementing the escape Coati Optimization Algorithm (eCOA) technique. The simulation of the CDM-BEOSAEM approach is accomplished under the ToN-IoT dataset, and the results are measured using various measures. The performance validation of the CDM-BEOSAEM approach portrayed a superior accuracy value of 99.29% over existing models.
Ebola virus disease sequelae and viral persistence in animal models: Implications for the future.
Ebola virus disease (EVD), caused by infection with Ebola virus, results in severe, acute illness with a high mortality rate. As the incidence of outbreaks of EVD increases and with the development and approval of medical countermeasures (MCMs) against the acute disease, late phases of EVD, including sequelae, recrudescence, and viral persistence, are occuring more frequently and are now a focus of ongoing research. Existing animal disease models recapitulate acute EVD but are not suitable to investigate the mechanisms of these late disease phenomena. Although there are challenges in establishing such a late disease model, the filovirus research community has begun to call for the development of an EBOV persistence model to address late disease concerns. Ultimately, this will aid the development of MCMs against late disease and benefit survivors of future EVD and filovirus outbreaks.
Exploring equity in global health collaborations: a qualitative study of donor and recipient power dynamics in Liberia.
IntroductionGlobal health collaborations between individuals from high-resource and low-resource settings are complex and often built on hierarchical structures and power differentials that are difficult to change. There have been many calls and frameworks developed to facilitate more equity within these collaborations, yet little is known about the lived experiences of global health donors and recipients working within such collaborations and how those experiences can facilitate more equitable collaboration. Liberia, a postconflict, post-Ebola country, provides an ideal setting to study lived experiences of global health collaborations.MethodsOur qualitative analysis used key informant interviews representing the perspectives of those working on behalf of the Liberian government, Liberian academics, foreign donors and non-governmental organisations and implementing partners. Thematic analysis guided this analysis to explore topics such as financial control, accountability and decision making.ResultsThe first phase of the analysis mapped the existing patterns of priority setting. Priority-setting power was most strongly held by those with financial control (donors), and implementation plans tended to be built on metrics that aim to meet donor expectations. The second phase of the analysis explored the interplay between underlying factors that we identified in our data associated with driving collaborative inequity: history of prior of engagement, level of transparency and patterns of accountability.ConclusionsOur findings highlight that global health collaborations in Liberia are structured to hinder equitable partnerships. The power structure tied to financial ownership offers little space for recipients to have an equitable role in collaborations, which maintains dependence on external aid and ensures that weak systems remain weak. While our study is limited to Liberia, we anticipate that these dynamics are common elsewhere and reinforce the importance of intentional efforts to ensure equitable decision making and power structures in similar settings worldwide.
Publicações recentes
Negative and ambisense RNA virus ribonucleocapsids: more than protective armor.
🥉 Relato de casoEbola virus disease: A narrative review.
Ebola virus disease: A review for the emergency medicine clinician.
Why doesn't Ebola virus cause pandemics like SARS-CoV-2?
📚 EuropePMC99 artigos no totalmostrando 199
Progressive Development of a New Tool for Rapid Thematic Analysis of Community Perceptions and Concerns During Health Emergencies.
Global health, science and practiceIntroducing a hybrid intrusion detection method for IoT-cloud environments based on ResNeXt and improved Ebola optimization search algorithm.
Scientific reportsEnhancing cyberthreat defense mechanisms using ensemble of representation learning with binary Ebola optimization search in internet of things environment.
Scientific reportsEstablishing Vitreoretinal Surgery Capacity in Sierra Leone: Challenges and Opportunities to Address Retinal Health Disparities in Resource-limited Settings.
International ophthalmology clinicsEbola virus disease sequelae and viral persistence in animal models: Implications for the future.
PLoS pathogensExploring equity in global health collaborations: a qualitative study of donor and recipient power dynamics in Liberia.
BMJ global healthBroad antibody and T cell responses to Ebola, Sudan, and Bundibugyo ebolaviruses using mono- and multi-valent adjuvanted glycoprotein vaccines.
Antiviral researchEbola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
PLoS biologyDetecting changes in the transmission rate of a stochastic epidemic model.
Statistics in medicine[Tropical sexually transmitted infections Summary of the SFMTSI Scientific Day of November 9, 2023].
Medecine tropicale et sante internationaleDesign of universal Ebola virus vaccine candidates via immunofocusing.
Proceedings of the National Academy of Sciences of the United States of AmericaProduction and Purification of Filovirus Glycoproteins.
Methods in molecular biology (Clifton, N.J.)Human MARCH1, 2, and 8 block Ebola virus envelope glycoprotein cleavage via targeting furin P domain.
Journal of medical virologySelective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats.
Nature communicationsSustaining Preparedness in Hospitals.
Advances in health care managementPreparing for another Ebola Outbreak: The impact of viral inactivation methods on commonly measured biochemistry analytes in plasma and urine.
Clinical biochemistryPiloting delivery of PfSPZ vaccines for malaria through a cryogenic vaccine cold chain to travel and military medicine clinics.
Journal of travel medicineRNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3'-leader region of genomic RNA.
Emerging microbes & infectionsThermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection.
VaccineMarkers of antroponotic viral infections in vervet monkeys arrived from their natural habitat (Tanzania).
Voprosy virusologiiA novel feature selection algorithm for identifying hub genes in lung cancer.
Scientific reportsReverse Genetics Systems for Filoviruses.
Methods in molecular biology (Clifton, N.J.)Pan-antiviral effects of a PIKfyve inhibitor on respiratory virus infection in human nasal epithelium and mice.
Antimicrobial agents and chemotherapyRegulation of Ebola GP conformation and membrane binding by the chemical environment of the late endosome.
PLoS pathogensBaseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts.
Frontiers in immunologySafety and immunogenicity of an Ad26.ZEBOV booster vaccine in Human Immunodeficiency Virus positive (HIV+) adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen against Ebola: A single-arm, open-label Phase II clinical trial in Kenya and Uganda.
VaccineImmunogenicity and Vaccine Shedding After 1 or 2 Doses of rVSVΔG-ZEBOV-GP Ebola Vaccine (ERVEBO®): Results From a Phase 2, Randomized, Placebo-controlled Trial in Children and Adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaThe evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell reportsExpediting approval for medical countermeasures to address high burden disease: an ethical justification to move beyond emergency use authorisation.
BMJ global healthSequence optimized diagnostic assay for Ebola virus detection.
Scientific reportsThe inclusion of pregnant women in vaccine clinical trials: An overview of late-stage clinical trials' records between 2018 and 2023.
VaccineSupporting the Manufacturing of Medical Supplies in Africa: Collaboration Between Africa CDC, Partners, and Member States.
Global health, science and practiceEffect of Interferon Gamma on Ebola Virus Infection of Primary Kupffer Cells and a Kupffer Cell Line.
VirusesIdentification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections.
Nature communicationsEbola virus VP35 perturbs type I interferon signaling to facilitate viral replication.
Virologica SinicaDonning and doffing of personal protective equipment for health care workers in a tertiary hospital in China: A simulation study.
Journal of occupational and environmental hygieneAdipose Tissues from Human and Bat-Derived Cell Lines Support Ebola Virus Infection.
VirusesNegative and ambisense RNA virus ribonucleocapsids: more than protective armor.
Microbiology and molecular biology reviews : MMBRLearning from implementation of a COVID case management desk guide and training: a pilot study in Sierra Leone.
BMC health services researchImmunological correlates of protection afforded by PHV02 live, attenuated recombinant vesicular stomatitis virus vector vaccine against Nipah virus disease.
Frontiers in immunologyEbola Virus Uses Tunneling Nanotubes as an Alternate Route of Dissemination.
The Journal of infectious diseasesIdentification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo.
Cell reportsDepletion of Bone Marrow Hematopoietic Cells in Ebolavirus-Infected Rhesus Macaques: A Possible Cause of Hematologic Abnormalities in Ebolavirus Disease.
The American journal of pathologySafety and Immunogenicity of the Heterologous 2-Dose Ad26.ZEBOV, MVA-BN-Filo Vaccine Regimen in Health Care Providers and Frontliners of the Democratic Republic of the Congo.
The Journal of infectious diseasesAntibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious DiseasesLow seroprevalence of Ebola virus in health care providers in an endemic region (Tshuapa province) of the Democratic Republic of the Congo.
PloS oneInterplay of Ebola Virus With Immune Cells Leading to Their Death by Diverse Mechanisms.
The Journal of infectious diseasesClinical and Immunologic Correlates of Vasodilatory Shock Among Ebola Virus-Infected Nonhuman Primates in a Critical Care Model.
The Journal of infectious diseasesThe Multiple Origins of Ebola Disease Outbreaks.
The Journal of infectious diseasesAutomatic detection and classification of lung cancer CT scans based on deep learning and ebola optimization search algorithm.
PloS oneContrasting effects of filamin A and B proteins in modulating filovirus entry.
PLoS pathogensEbola Virus Infection Induces HCAR2 Expression Leading to Cell Death.
The Journal of infectious diseasesAn Antiviral Role for TRIM14 in Ebola Virus Infection.
The Journal of infectious diseasesThe Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection.
VirusesAtypical Ebola Virus Disease in a Rhesus Macaque.
The Journal of infectious diseasesA Single Case Observation: Is the Ebola Virus Soluble Glycoprotein an Indicator of Viral Recrudescence?
The Journal of infectious diseasesLimited Benefit of Postexposure Prophylaxis With VSV-EBOV in Ebola Virus-Infected Rhesus Macaques.
The Journal of infectious diseasesSingle-dose VSV-based vaccine protects cynomolgus macaques from disease after Taï Forest virus infection.
Emerging microbes & infectionsA Single-Dose Intranasal Combination Panebolavirus Vaccine.
The Journal of infectious diseasesSpatial and functional arrangement of Ebola virus polymerase inside phase-separated viral factories.
Nature communicationsEbola Virus Tropism in Ex Vivo Cynomolgus Macaque Ocular Tissues.
The Journal of infectious diseasesThe Mucin-Like Domain of the Ebola Glycoprotein Does Not Impact Virulence or Pathogenicity in Ferrets.
The Journal of infectious diseasesEbola virus disease: A narrative review.
Microbial pathogenesisNatural History of Nonhuman Primates After Oral Exposure to Ebola Virus Variant Makona.
The Journal of infectious diseases[When serology contradicts the experience of the disease: Ethics, research, and announcements about Ebola in Guinea].
Sante publique (Vandoeuvre-les-Nancy, France)Ebola virus inclusion bodies are liquid organelles whose formation is facilitated by nucleoprotein oligomerization.
Emerging microbes & infectionsN6-methyladenosine is required for efficient RNA synthesis of Ebola virus and other haemorrhagic fever viruses.
Emerging microbes & infectionsA Recombinant Vesicular Stomatitis Virus-Based Vaccine Provides Postexposure Protection Against Bundibugyo Ebolavirus Infection.
The Journal of infectious diseasesA Pan-Ebolavirus Monoclonal Antibody Cocktail Provides Protection Against Ebola and Sudan Viruses.
The Journal of infectious diseasesThe Inability of Marburg Virus to Cause Disease in Ferrets Is Not Solely Linked to the Virus Glycoprotein.
The Journal of infectious diseasesEbola Virus Disease Features Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome in the Rhesus Macaque Model.
The Journal of infectious diseasesCOVID-19 vaccines and the pandemic: lessons learnt for other neglected diseases and future threats.
BMJ global healthEbolavirus Species-Specific Interferon Antagonism Mediated by VP24.
VirusesReemergence of Marburgvirus disease: Update on current control and prevention measures and review of the literature.
Reviews in medical virologyEbola virus disease: A review for the emergency medicine clinician.
The American journal of emergency medicineSingle-Dose Treatment With Vesicular Stomatitis Virus-Based Ebola Virus Vaccine Expressing Ebola Virus-Specific Artificial Micro-RNA Does Not Protect Mice From Lethal Disease.
The Journal of infectious diseasesMagnetic Resonance Imaging for Monitoring of Hepatic Disease Induced by Ebola Virus: a Nonhuman Primate Proof-of-Concept Study.
Microbiology spectrumMarburg Virus Disease: Global Threat or Isolated Events?
The Journal of infectious diseasesA Highly Attenuated Panfilovirus VesiculoVax Vaccine Rapidly Protects Nonhuman Primates Against Marburg Virus and 3 Species of Ebola Virus.
The Journal of infectious diseasesImmune correlates of protection for SARS-CoV-2, Ebola and Nipah virus infection.
Frontiers in immunologyDevelopment of immortalized rhesus macaque kidney cells supporting infection with a panel of viruses.
PloS onePathogenesis of Aerosolized Ebola Virus Variant Makona in Nonhuman Primates.
The Journal of infectious diseasesFluorescent and Bioluminescent Reporter Mouse-Adapted Ebola Viruses Maintain Pathogenicity and Can Be Visualized in Vivo.
The Journal of infectious diseasesStructural and Energetic Basis for Differential Binding of Ebola and Marburg Virus Glycoproteins to a Bat-Derived Niemann-Pick C1 Protein.
The Journal of infectious diseasesDevelopment of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats.
VirusesEstablishing a Mouse Model for Sexual Transmission and Male Reproductive Tract Persistence of Ebola Virus.
The Journal of infectious diseasesImmune response of a two-dose heterologous Ebola vaccine regimen: summary of three African clinical trials using a single validated Filovirus Animal Nonclinical Group enzyme-linked immunosorbent assay in a single accredited laboratory.
EBioMedicineAntibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates.
Cell reportsSphingosine Kinases Promote Ebola Virus Infection and Can Be Targeted to Inhibit Filoviruses, Coronaviruses, and Arenaviruses Using Late Endocytic Trafficking to Enter Cells.
ACS infectious diseasesSystematic analysis of human antibody response to ebolavirus glycoprotein shows high prevalence of neutralizing public clonotypes.
Cell reportsN'-Phenylacetohydrazide Derivatives as Potent Ebola Virus Entry Inhibitors with an Improved Pharmacokinetic Profile.
Journal of medicinal chemistryPotential use of the cholesterol transfer inhibitor U18666A as an antiviral drug for research on various viral infections.
Microbial pathogenesisMagnetic biosensors for identification of SARS-CoV-2, Influenza, HIV, and Ebola viruses: a review.
NanotechnologyModelling the impact of stigmatisation of Ebola survivors on the disease transmission dynamics.
Scientific reportsEbola virus-like particles reprogram cellular metabolism.
Journal of molecular medicine (Berlin, Germany)Natural history of nonhuman primates after conjunctival exposure to Ebola virus.
Scientific reportsApproaches to demonstrating the effectiveness of filovirus vaccines: Lessons from Ebola and COVID-19.
Frontiers in immunologySolidarity Against Ebola: an update.
The Lancet. MicrobeCharacterization of an air-liquid interface primary human vaginal epithelium to study Ebola virus infection and testing of antivirals.
Antiviral researchInfectious diseases, dividend policy, and independent directors: Evidence from textual analysis.
PloS oneCellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP).
VaccineStructure of the Inmazeb cocktail and resistance to Ebola virus escape.
Cell host & microbeEbola Virus Activates IRE1α-Dependent XBP1u Splicing.
VirusesInactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation.
VirusesEbola virus disrupts the inner blood-retinal barrier by induction of vascular endothelial growth factor in pericytes.
PLoS pathogensA high-throughput single-particle imaging platform for antibody characterization and a novel competition assay for therapeutic antibodies.
Scientific reportsOf mice and Mike-An underappreciated Ebola virus disease model may have paved the road for future filovirology.
Antiviral researchHost antiviral factors hijack furin to block SARS-CoV-2, ebola virus, and HIV-1 glycoproteins cleavage.
Emerging microbes & infectionsIn vivo characterization of the novel ebolavirus Bombali virus suggests a low pathogenic potential for humans.
Emerging microbes & infectionsHistory and impact of the mouse-adapted Ebola virus model.
Antiviral researchMouse models of Ebola virus tolerance and lethality: characterization of CD-1 mice infected with wild-type, guinea pig-adapted, or mouse-adapted virus.
Antiviral researchMaternal Immunization Using a Protein Subunit Vaccine Mediates Passive Immunity against Zaire ebolavirus in a Murine Model.
VirusesTraits, phylogeny and host cell receptors predict Ebolavirus host status among African mammals.
PLoS neglected tropical diseasesMultiplication of defective Ebola virus in a complementary permissive cell line.
Antiviral researchA single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates.
Science translational medicineSimilarities in the histological mouse model of early herpes simplex retinopathy with punctate inner choroidopathy and Ebola virus disease retinopathy.
European journal of ophthalmologyEbola virus L-VP35 structure.
Nature structural & molecular biologyWhy doesn't Ebola virus cause pandemics like SARS-CoV-2?
Microbial risk analysisImmunity-based Ebola optimization search algorithm for minimization of feature extraction with reduction in digital mammography using CNN models.
Scientific reportsActivation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation.
Cell reportsRNF185 regulates proteostasis in Ebolavirus infection by crosstalk between the calnexin cycle, ERAD, and reticulophagy.
Nature communicationsConstructing, validating, and updating machine learning models to predict survival in children with Ebola Virus Disease.
PLoS neglected tropical diseasesFirst-in-human study to evaluate safety, tolerability, and immunogenicity of heterologous regimens using the multivalent filovirus vaccines Ad26.Filo and MVA-BN-Filo administered in different sequences and schedules: A randomized, controlled study.
PloS oneCAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells.
VirusesmiR-142 Targets TIM-1 in Human Endothelial Cells: Potential Implications for Stroke, COVID-19, Zika, Ebola, Dengue, and Other Viral Infections.
International journal of molecular sciencesMultimerization of Ebola GPΔmucin on protein nanoparticle vaccines has minimal effect on elicitation of neutralizing antibodies.
Frontiers in immunologyEbola virus infection induces a delayed type I IFN response in bystander cells and the shutdown of key liver genes in human iPSC-derived hepatocytes.
Stem cell reportsEnhanced In Vitro and In Vivo Potency of a T Cell Epitope in the Ebola Virus Glycoprotein Following Amino Acid Replacement at HLA-A*02:01 Binding Positions.
Journal of virologyPost-Ebola Symptoms 7 Years After Infection: The Natural History of Long Ebola.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of AmericaEvidence for Viral mRNA Export from Ebola Virus Inclusion Bodies by the Nuclear RNA Export Factor NXF1.
Journal of virologyLessons learned for surveillance system strengthening through capacity building and partnership engagement in post-Ebola Guinea, 2015-2019.
Frontiers in public healthDR Congo rushes to contain resurgence of Ebola virus.
BMJ (Clinical research ed.)Ligand-based design of peptide entry inhibitors targeting the endosomal receptor binding site of filoviruses.
Antiviral researchThe cytoplasmic tail substitution increases the assembly efficiency of Ebola virus glycoprotein on the budded virus of Bombyx mori nucleopolyhedrovirus.
Protein expression and purificationWhat effect might border screening have on preventing importation of COVID-19 compared with other infections?: considering the additional effect of post-arrival isolation.
Epidemiology and infectionPrevalence of malaria and helminth infections in rural communities in northern Sierra Leone, a baseline study to inform Ebola vaccine study protocols.
PloS oneEngineering Antiviral Agents via Surface Plasmon Resonance.
Journal of visualized experiments : JoVESafety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial.
TrialsHuman Pegivirus Type 1: A Common Human Virus That Is Beneficial in Immune-Mediated Disease?
Frontiers in immunologyAdipocytes are susceptible to Ebola Virus infection.
VirologyNatural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques.
Emerging microbes & infectionsTranschromosomic bovines-derived broadly neutralizing antibodies as potent biotherapeutics to counter important emerging viral pathogens with a special focus on SARS-CoV-2, MERS-CoV, Ebola, Zika, HIV-1, and influenza A virus.
Journal of medical virologyWhy does viral RNA sometimes persist after recovery from acute infections?
PLoS biology3,4-Seco-Isopimarane Diterpenes from the Twigs and Leaves of Isodon Flavidus.
Molecules (Basel, Switzerland)A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge.
PLoS neglected tropical diseasesPandemic, Epidemic, Endemic: B Cell Repertoire Analysis Reveals Unique Anti-Viral Responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus.
Frontiers in immunologyEpitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.
PLoS pathogensUbiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
PLoS pathogensTRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction.
PLoS pathogensComplement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis.
Frontiers in immunologyContributions of the Regional Emerging Special Pathogen Treatment Centers to the US COVID-19 Pandemic Response.
Health securityA cryptic pocket in Ebola VP35 allosterically controls RNA binding.
Nature communicationsIncreasing International Collaboration and Networking Among High-level Isolation Units and Programs.
Health securityViral haemorrhagic fevers and malaria co-infections among febrile patients seeking health care in Tanzania.
Infectious diseases of povertyComparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in an Immune-Deficient Mouse.
VirusesAutomated Laser-Transfer Synthesis of High-Density Microarrays for Infectious Disease Screening.
Advanced materials (Deerfield Beach, Fla.)Antibody cocktail eliminates ebolaviruses.
Nature reviews. Drug discoveryInferring the reproduction number using the renewal equation in heterogeneous epidemics.
Journal of the Royal Society, InterfaceIdentification of novel Ebola virus inhibitors using biologically contained virus.
Antiviral researchFunctional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication.
Cell reportsAsymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
CellFindings and Implications From an Evaluation of the Gold Star Campaign in Post-Ebola Guinea: The Role of Gender and Education.
Global health, science and practiceSpatial model of Ebola outbreaks contained by behavior change.
PloS oneOn the possibility of oscillating in the Ebola virus dynamics and investigating the effect of the lifetime of T lymphocytes.
PloS onePan-ebolavirus serology study of healthcare workers in the Mbandaka Health Region, Democratic Republic of the Congo.
PLoS neglected tropical diseasesIdentification of novel chemical compounds targeting filovirus VP40-mediated particle production.
Antiviral researchFirst laboratory confirmation and sequencing of Zaire ebolavirus in Uganda following two independent introductions of cases from the 10th Ebola Outbreak in the Democratic Republic of the Congo, June 2019.
PLoS neglected tropical diseasesRemdesivir and Human Milk: A Case Study.
Journal of human lactation : official journal of International Lactation Consultant Association"Is There Anything Else You Would Like to Add?": The Ethics of (Not) Addressing Research Participants' Top Concerns in Public Health Emergency Health Research.
Frontiers in public healthEbola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors.
Science translational medicineFrom viral evolution to spatial contagion: a biologically modulated Hawkes model.
Bioinformatics (Oxford, England)Best practices of highly infectious decedent management: Consensus recommendations from an international expert workshop.
Journal of occupational and environmental hygieneCryo-EM analysis of Ebola virus nucleocapsid-like assembly.
STAR protocolsThe 2018-2020 Ebola Outbreak in the Democratic Republic of Congo: A Better Response Had Been Achieved Through Inter-State Coordination in Africa.
Risk management and healthcare policyRegistered Nurses' Perceptions After a Patient with Ebola Virus Disease Is Admitted to Their Hospital.
Health securityEthical and sociocultural challenges in managing dead bodies during epidemics and natural disasters.
BMJ global healthStructure, Process, and Outcomes of Liberian National Nursing and Midwifery Curricular Revisions.
Annals of global healthCoexpression of respiratory syncytial virus (RSV) fusion (F) protein and attachment glycoprotein (G) in a vesicular stomatitis virus (VSV) vector system provides synergistic effects against RSV infection in a cotton rat model.
VaccineThe Brief Case: A 6-Year-Old with Fever, Abdominal Pain, and Recent Travel to Sierra Leone.
Journal of clinical microbiologyExperts criticise WHO response to sex abuse allegations.
Lancet (London, England)Role of Key Infectivity Parameters in the Transmission of Ebola Virus Makona in Macaques.
The Journal of infectious diseases[Flow cytometry evaluation of the rhesus monkey cellular immunity following the Zaire ebolavirus (Filoviridae; Ebolavirus: Zaire ebolavirus) experimental infection].
Voprosy virusologiiMarta Lado-Ebola, HIV, sexual health and more.
The Lancet. Infectious diseasesModulation of immune response in Ebola virus disease.
Current opinion in pharmacologySingle-vial filovirus glycoprotein vaccines: Biophysical characteristics and immunogenicity after co-lyophilization with adjuvant.
VaccineEnabling Artificial Intelligence for Genome Sequence Analysis of COVID-19 and Alike Viruses.
Interdisciplinary sciences, computational life sciencesConserved immunogenic peptides of Ebola glycoprotein elicit immune response in human peripheral blood mononuclear cells.
Microbiology and immunologyDelays in reporting and publishing trial results during pandemics: cross sectional analysis of 2009 H1N1, 2014 Ebola, and 2016 Zika clinical trials.
BMC medical research methodologyPooled Analysis of the Accuracy of Xpert Ebola Assay for Diagnosing Ebola Virus Infection.
BioMed research internationalEbola Virus IgG Seroprevalence in Southern Mali.
Emerging infectious diseasesRetention of healthcare workers 1 year after recruitment and deployment in rural settings: an experience post-Ebola in five health districts in Guinea.
Human resources for healthA multi-stage stochastic programming approach to epidemic resource allocation with equity considerations.
Health care management scienceThe Ferret as a Model for Filovirus Pathogenesis and Countermeasure Evaluation.
ILAR journalEarly Experiences in the Integration of Non-communicable Diseases into Emergency Primary Health Care, Beni Region, Democratic Republic of the Congo.
Annals of global healthIncreased Likelihood of Detecting Ebola Virus RNA in Semen by Using Sample Pelleting.
Emerging infectious diseasesLiberia's Community Health Assistant Program: Scale, Quality, and Resilience.
Global health, science and practice[eLearning approach for capacity strengthening of health professionals in Guinea: A post-Ebola experience].
Sante publique (Vandoeuvre-les-Nancy, France)[Ebola virus (Filoviridae: Ebolavirus: Zaire ebolavirus): fatal adaptation mutations].
Voprosy virusologiiWhat factors shape surgical access in West Africa? A qualitative study exploring patient and provider experiences of managing injuries in Sierra Leone.
BMJ openAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
Ainda não temos associações cadastradas para Febre hemorrágica do Ebola.
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Comunidades
Grupos ativos de quem convive com esta doença aqui no Raras
Ainda não existe comunidade no Raras para Febre hemorrágica do Ebola
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Progressive Development of a New Tool for Rapid Thematic Analysis of Community Perceptions and Concerns During Health Emergencies.
- Introducing a hybrid intrusion detection method for IoT-cloud environments based on ResNeXt and improved Ebola optimization search algorithm.
- Enhancing cyberthreat defense mechanisms using ensemble of representation learning with binary Ebola optimization search in internet of things environment.
- Ebola virus disease sequelae and viral persistence in animal models: Implications for the future.
- Exploring equity in global health collaborations: a qualitative study of donor and recipient power dynamics in Liberia.
- Ebola Virus Disease.
- Negative and ambisense RNA virus ribonucleocapsids: more than protective armor.
- Ebola virus disease: A narrative review.
- Ebola virus disease: A review for the emergency medicine clinician.
- Why doesn't Ebola virus cause pandemics like SARS-CoV-2?
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:319218(Orphanet)
- MONDO:0005737(MONDO)
- GARD:2035(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q51993(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
