Crioglobulinemia mista

Vasculitis Pregnancy Registry

NCT02593565

RECRUTANDO

Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

NCT03004326

RECRUTANDO

A Multicenter Phase 2 Single-arm Proof-of-concept Trial Assessing the Efficacy and Safety of Obinutuzumab in the Treatment of Non-infectious Active Cryoglobulinemia Vasculitis Refractory or Intolerant to Rituximab

NCT07268521

EM ANDAMENTO

Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis

NCT05168475

DESCONHECIDO

Isatuximab in Type I Cryoglobulinemia

NCT05114109

DESCONHECIDO

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NCT02593565 · Vasculitis Pregnancy RegistryRecrutando

NCT03004326 · Clinical Transcriptomics in Systemic Vasculitis (CUTIS)Recrutando

Outros ensaios clínicos

11 ensaios clínicos encontrados, 3 ativos.

Distribuição por fase

NCT07268521 · A Multicenter Phase 2 Single-arm Proof-of-concept Trial Asse…Em breve

NCT05168475 · Biologics in Refractory Vasculitis: A Trial of Biologic Ther…Encerrado

NCT05114109 · Isatuximab in Type I CryoglobulinemiaUNKNOWN

NCT04692363 · Plasmapheresis Before Rituximab in CryoglobulinemiaUNKNOWN

NCT03410290 · Journey of Patients With Vasculitis From First Symptom to Di…Concluído

NCT02476292 · Impact of Vasculitis on Employment and IncomeConcluído

NCT00029107 · Rituximab to Treat Hepatitis C-Associated Cryoglobulinemic V…Concluído

Ver todos no ClinicalTrials.gov

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Publicações mais relevantes

Timeline de publicações

293 papers (10 anos)

#1

Pearls & Oy-sters: Reversible Leukoencephalopathy and Parkinsonism Due to CNS Involvement in Cryoglobulinemia.

Neurology2026 Feb 10

We present a case of reversible leukoencephalopathy and parkinsonism associated with type III mixed cryoglobulinemic vasculitis in a patient who initially presented with systemic vasculitic symptoms such as rash and arthralgias. Neither hepatitis C nor monoclonal gammopathy-typical triggers of cryoglobulinemia-was identified. The neurologic syndrome evolved with tremor, rigidity, significant cognitive decline, and extensive white matter abnormalities on MRI, mimicking primary neurodegenerative conditions such as multiple system atrophy. Diagnostic workup ruled out infectious, metabolic, autoimmune, and drug-related etiologies. After immunosuppressive therapy with methotrexate and steroids, the patient experienced marked clinical and radiologic improvement, paralleled by a decline in serum neurofilament levels. This case highlights the importance of recognizing inflammatory CNS involvement as a potentially reversible cause of rapidly progressive parkinsonism and cognitive impairment. Prompt identification and timely immunosuppressive treatment may reverse symptoms and prevent permanent neurologic damage.

#2

Resolution of Hepatitis Delta Virus-Related Cryoglobulinemic Vasculitis With the Use of Bulevirtide.

ACG case reports journal2026 Mar

The global prevalence of hepatitis B virus (HBV) infection is around 257 million people, and about 5% are coinfected with hepatitis delta virus (HDV). HDV infection can progress from acute fulminant hepatitis to chronic hepatitis, cirrhosis, or hepatocellular carcinoma. About 20% of HBV patients develop extrahepatic manifestations; among them, cryoglobulinemic vasculitis (CV) occurs in less than 5% of cases and can lead to heterogeneous clinical manifestations. We present the case of a woman with HBV-HDV coinfection who was referred to our clinic with suspected virus-related CV. One-year treatment with bulevirtide led to complete and durable resolution of CV.

#3

Short-Term Clinical and Immunologic Outcomes Conditional on SVR12 in Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis Treated With Direct-Acting Antivirals: A Systematic Review and Meta-Analysis.

Cureus2026 Feb

In contemporary clinical practice, direct-acting antiviral therapy (DAA) produces high rates of sustained virologic response (SVR) among patients with hepatitis C virus infection; however, short-term clinical and immunologic outcomes following viral eradication in HCV-associated cryoglobulinemic vasculitis remain incompletely characterized, particularly among patients who have already achieved SVR12. A systematic review and meta-analysis was performed to evaluate short-term outcomes conditional on achieving SVR12 among patients with symptomatic HCV-associated cryoglobulinemic vasculitis treated with interferon-free DAA therapy. EMBASE and PubMed were searched from inception through January 2026, and two reviewers independently screened studies and extracted data. Pooled proportions of complete clinical response, partial clinical response, and complete immunologic response at the time of SVR12 were calculated using random-effects models. Eighteen observational studies were included. Among patients who achieved SVR12, the pooled proportion of complete clinical response was 64.8% (95% CI: 49.6%-79.3%), while partial clinical response occurred in 23.8% (95% CI: 18.3%-30.4%). Complete immunologic response was observed in 43.9% of patients (95% CI: 36.6%-51.5%). Substantial heterogeneity was observed for clinical outcomes reflecting differences across observational cohorts, whereas heterogeneity was lower for immunologic response. In conclusion, among patients with HCV-associated cryoglobulinemic vasculitis who achieved SVR12 with DAA therapy, short-term clinical improvement was common, although complete immunologic normalization was less frequent. These findings provide clinically relevant prognostic information regarding early expectations following viral eradication, while highlighting that longer-term durability of response requires ongoing evaluation.

#4

Lingual Raynaud's Phenomenon: A Case Series and Literature Review.

Journal of clinical medicine2026 Feb 25

Background: Raynaud's phenomenon of the tongue is a rare manifestation that may be associated with systemic diseases. The clinical manifestations, etiologies and management of this condition are poorly described. Methods: We report 10 cases of lingual Raynaud's phenomenon (LRP) and 26 cases from a structured literature review. Results: In 38.8% of cases, the LRP occurred in the context of a previously diagnosed systemic sclerosis; 16.6% followed radiotherapy for head and neck cancer; and 27.8% of patients presented with an idiopathic-like form. The manifestations classically included a syncopal phase (91.7%) associated with hypoesthesia (88.9%) and possible dysarthria (52.8%). Atypical presentations with a primary cyanotic phase were also observed, particularly in the context of vasculitis, notably cryoglobulinemic vasculitis (four patients). Active smoking was a significant triggering factor in idiopathic forms (60%). Across all patients-both primary and secondary forms-the most common triggering factor was cold exposure (75%). Vasodilator use showed good efficacy and should be considered for all highly symptomatic patients. Conclusions: In summary, LRP is more frequently associated with systemic sclerosis, manifesting as blanching of the tongue associated with hypoesthesia and dysarthria in more than half of cases. Vasodilators may reduce symptoms. Larger studies are needed to confirm these findings.

#5

Cryoglobulinemia, monoclonal and mixed cryoglobulinemia syndromes, cryoglobulinemic vasculitis: a proposal for comprehensive nomenclature and definition.

Frontiers in immunology2026

Cryoglobulinemia indicates the reversible, cold-dependent precipitation of immunoglobulins (Ig), which may be monoclonal (MoC) or mixed IgG-IgM (MC). Although this in vitro phenomenon is relatively frequent, only a minority of cases develop clinically relevant manifestations, often falling within lymphoproliferative, autoimmune, or infectious disease domains. This complexity highlights the need for clearer nomenclature and definition systems. The term "cryoglobulinemia" is often used interchangeably to describe either simple laboratory finding, asymptomatic cryo-Ig precipitation (MoC or MC) or corresponding clinical syndromes (MoCs or MCs). This overlap creates ambiguity, hinders expert communication, and complicates the comparison of clinical studies. A standardized nomenclature is therefore essential to define disease subsets, establish boundaries with related conditions, and enable reliable data collection and multicenter analyses. When cryoglobulins are detected, the cryoprecipitate must be isolated and defined as MoC or MC, followed by a systematic clinical and laboratory assessment to identify potential underlying disorders. Immunoserological, microbiological, and pathological investigations are required to classify both MoC and MC as asymptomatic or symptomatic, and as essential or secondary. Asymptomatic individuals must be monitored over time for potential progression to overt clinical syndromes; similarly, those with essential forms require surveillance for the emergence of systemic diseases. Possible overlap with autoimmune conditions, particularly Sjögren's disease, should always be considered. Despite some shared features, MoCs and MCs represent distinct clinical entities. Accurate diagnosis relies primarily on cryoprecipitate analysis. MoCs are usually associated with thrombotic, non-inflammatory microangiopathy and lymphoproliferative disorders, whereas MCs are characterized by immune-complex-mediated leukocytoclastic vasculitis, complement consumption, and frequent association with viral infections, especially HCV and HBV. The introduction of new-generation antivirals in the last decade has markedly reduced the prevalence of virus-related MCs in more developed countries. A harmonized nomenclature and standardized definitions for various cryoglobulinemia subsets, supported by careful clinical-immunological and pathological characterization, are essential to improve diagnostic accuracy, ensure interobserver consistency, and enable the development of evidence-based, mechanism-driven therapies for major cryoglobulinemic syndromes.

Publicações recentes

Systemic vasculitis: one year in review 2026.

Clin Exp Rheumatol2026 Mar 27

A Case of Cryoglobulinemic Vasculitis: Linking Thymectomy, Autoimmune Disease, and Lymphomagenesis.

Kidney Med2026 Apr

Resolution of Hepatitis Delta Virus-Related Cryoglobulinemic Vasculitis With the Use of Bulevirtide.

ACG Case Rep J2026 Mar

Short-Term Clinical and Immunologic Outcomes Conditional on SVR12 in Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis Treated With Direct-Acting Antivirals: A Systematic Review and Meta-Analysis.

Cureus2026 Feb

Lingual Raynaud's Phenomenon: A Case Series and Literature Review.

J Clin Med2026 Feb 25

Ver todas no PubMed

📚 EuropePMC219 artigos no totalmostrando 196

Resolution of Hepatitis Delta Virus-Related Cryoglobulinemic Vasculitis With the Use of Bulevirtide.

ACG case reports journal

Short-Term Clinical and Immunologic Outcomes Conditional on SVR12 in Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis Treated With Direct-Acting Antivirals: A Systematic Review and Meta-Analysis.

Lingual Raynaud's Phenomenon: A Case Series and Literature Review.

Cryoglobulinemia, monoclonal and mixed cryoglobulinemia syndromes, cryoglobulinemic vasculitis: a proposal for comprehensive nomenclature and definition.

American journal of hematology

Long Term Outcomes in Patients With Non-Infectious Mixed Cryoglobulinemic Vasculitis.

A Rare Large-Artery Complication of Cryoglobulinemia: Superior Gluteal Artery Pseudoaneurysm.

JACC. Case reports

[Cryoglobulinemia and HCV-infection: stages of study].

Pearls & Oy-sters: Reversible Leukoencephalopathy and Parkinsonism Due to CNS Involvement in Cryoglobulinemia.

Neurology

Localized Immune-Complex Small-Vessel Vasculitis Presenting as Unilateral Myositis After Hepatitis A.

The American journal of case reports

Mixed Cryoglobulinemia in the Setting of Monoclonal B-Cell Lymphocytosis and Monoclonal Gammopathy of Unknown Significance: A Case Report.

Cryoglobulinemic Vasculitis Manifesting as Rapidly Progressive Glomerulonephritis: A Case Report.

Type I Cryoglobulinemia Associated With Multiple Myeloma: A Case Report.

Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.

Frontiers in medicine

Cutaneous Vasculitis in Primary Sjögren Disease.

JAMA dermatology

A case of constrictive pericarditis and cryoglobulinemic vasculitis in a patient with Whipple's disease.

Healthcare (Basel, Switzerland)

Impact of Direct-Acting Antivirals on Extrahepatic Manifestations in Chronic Hepatitis C: A Narrative Review with a Hermeneutic Approach.

Revealing the pathogenesis of vasculitis induced by aggregation of cryoglobulins associated with the immune response through an in vitro study.

Nanoscale

Monoclonal Gammopathy of Rheumatologic Significance (MGRhS): a systemic vision of clonal disorders with multiple organ involvement.

Cryoglobulinemic vasculitis flare after daratumumab.

Annals of hematology

A Case of Cryoglobulinemic Nephritis That Responded to Rituximab Monotherapy.

Renal Involvement in Mixed Cryoglobulinemic Vasculitis: Current Perspectives.

Hepatitis C Virus Associated Cryoglobulinemic Vasculitis.

Report of Consensus Panel 1 from the 12th International Workshop on the management of patients with IgM and Waldenstrom's Macroglobulinemia related neuropathy.

Seminars in hematology

Systemic Involvement of Leukocytoclastic Vasculitis in Skin of Color.

A Rare Gastrointestinal Manifestation of Cryoglobulinemic Vasculitis: A Case Report.

Digestive diseases and sciences

Long Term Follow-Up of Patients with Cryoglobulinemia After Successful Treatment of Chronic C Virus Hepatitis.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

High detection rate for perivascular deposits of immunoglobulins in immune complex vasculitis from biopsies of early macular lesions.

Spontaneous Bacterial Peritonitis Beyond the Usual Suspects: Case Series of Salmonella and Brucella With Comprehensive Literature Review.

Clinical case reports

Type i cryoglobulinemic vasculitis associated to monoclonal gammopathy of uncertain significance successfully treated with bortezomib plus dexamethasone.

Medicina clinica

[Geographic-like paraproteinemic keratopathy in type I cryoglobulinemic vasculitis: a case report].

Die Ophthalmologie

Epstein-Barr Virus Related Mixed Cryoglobulinemic Vasculitis with Multi-System Involvement.

A triad of somatic mutagenesis converges in self-reactive B cells to cause a virus-induced autoimmune disease.

Immunity

Myopericarditis in a Patient With Cryoglobulinemic Kidney Disease: A Case Report.

Successful treatment with bortezomib for refractory cryoglobulinemic vasculitis triggered by ischemic non-obstructive coronary artery disease.

CEN case reports

Rheumatology (Oxford, England)

Immune checkpoint inhibitors-associated vasculitis: a heterogeneous condition with possible severe disease course.

Non-infectious mixed cryoglobulinemia as a new clinical presentation of mutation in the gene encoding coatomer subunit alpha: a case report of two adult sisters.

Current rheumatology reviews

A Rare Presentation of Cryoglobulinemic Vasculitis Associated with Primary Sjögren's Syndrome.

Recurrent localized fever caused by cryoglobulinemic vasculitis following hemodialysis: A case report.

CEN case reports

Cryoglobulinemic vasculitis triggered by Staphylococcus aureus endocarditis with chronic hepatitis C virus co-infection: a case report and literature review.

Influenza vaccination-associated cryoglobulinemic vasculitis.

Clinical nephrology

An Unusual Case of Cryoglobulinemic Vasculitis and Acute Disseminating Encephalomyelitis in a 21-Year-Old Caucasian Male.

Monoclonal gammopathy of clinical significance in a young patient treated with melphalan-thalidomide-prednisone.

Clinical case reports

A comparative study of different antiviral treatment protocols in HCV related cryoglobulinemic vasculitis.

Scientific reports

Tubulointerstitial nephritis with IgG4-positive plasma cell infiltration and tertiary lymphoid tissue in a patient with cryoglobulinemic vasculitis: a case report.

CEN case reports

American journal of respiratory and critical care medicine

Essential Mixed Cryoglobulinemic Vasculitis: Sole Onset with Acute Respiratory Distress Syndrome.

Hepatitis C virus-related autoimmunity before and after viral clearance: a single center, prospective, observational study.

International journal of rheumatic diseases

Cryoglobulinemic vasculitis complicating Sjögren's syndrome with IgA accumulation.

Advances in kidney disease and health

Liver Disease-Associated Glomerulopathies.

Cryoglobulinemic vasculitis and membranoproliferative glomerulonephritis in a patient with cured virus C infection.

Nefrologia

Journal of vitreoretinal diseases

Cryoglobulin-Associated Retinal Vasculitis: Retrospective Case Series.

[Comparative analysis of the development mechanisms of cryoglobulinemic vasculitis and Sjögren's syndrome].

Arkhiv patologii

Type III cryoglobulinemia associated with monoclonal gammopathy of uncertain significance and presenting with retiform purpura.

JAAD case reports

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

A Rare Case of Nephrotic Syndrome in the Setting of Sjogren Syndrome-related Cryoglobulinemic Vasculitis.

Cryoglobulinemic vasculitis with blood schistocytosis and bone marrow vasculitis.

EJHaem

Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients.

Immunologic research

Extrahepatic manifestations of HCV where do we stand?

Medicina clinica

Therapeutic Potential of Rituximab in Managing Hepatitis C-Associated Cryoglobulinemic Vasculitis: A Systematic Review.

Neuroimaging clinics of North America

Imaging of Small Artery Vasculitis.

Current opinion in rheumatology

Cryoglobulinemic vasculitis: a 2023 update.

Rare manifestations of cryoglobulinemic vasculitis: a case report.

Autoimmune Hepatitis in a Patient With Cryoglobulinemic Vasculitis: A Rare Association.

Efficacy of Therapeutic Apheresis for Cryoglobulinemic Vasculitis Patients with Renal Involvement: A Systematic Review.

Blood purification

Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.

Acta gastro-enterologica Belgica

Local and systemic autoimmune manifestations linked to hepatitis A infection.

Ocular manifestations of cryoglobulinemia: a reappraisal.

Eye (London, England)

American journal of kidney diseases : the official journal of the National Kidney Foundation

Cryoglobulinemic Vasculitis in Disguise: Cryofibrinogenemia as Variant of Monoclonal Gammopathy of Renal Significance.

Expert review of clinical immunology

Recent updates in the diagnosis and management of cryoglobulinemic vasculitis.

International journal of molecular sciences

Serological and Molecular Characterization of Hepatitis C Virus-Related Cryoglobulinemic Vasculitis in Patients without Cryoprecipitate.

Risk factors for relapse in non-infectious cryoglobulinemic vasculitis, including type I cryoglobulinemia: a systematic review.

Internal medicine (Tokyo, Japan)

Type II Cryoglobulinemic Membranoproliferative Glomerulonephritis Caused by Mucosa-associated Lymphoid Tissue Lymphoma.

The New England journal of medicine

Type I Cryoglobulinemic Vasculitis.

Internal medicine (Tokyo, Japan)

Type 1 Cryoglobulinemic Vasculitis Due to Monoclonal Gammopathy of Undetermined Significance Successfully Treated by Bortezomib Plus Dexamethasone.

Best practice & research. Clinical rheumatology

Cardiovascular risk in vasculitis.

Biologic therapy in large and small vessels vasculitis, and Behçet's disease: Evidence- and practice-based guidance.

Rinsho shinkeigaku = Clinical neurology

[Diagnosis of cryoglobulinemic vasculitis based on B symptoms and peripheral neuropathy: a case report].

Journal of cutaneous medicine and surgery

Cryoglobulinemic Vasculitis With Targetoid Purpura.

Acute cryoglobulinemic vasculitis following rituximab infusion for waldenström macroglobulinemia.

JAAD case reports

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology

[A case of hepatitis C virus-related mixed cryoglobulinemic vasculitis with chronic diarrhea].

Systemic Neoplastic Cryoglobulinemic Vasculitis Mimics Large Vessel Occlusion: A Case Report.

The neurologist

Pathophysiology and clinical manifestations of immune complex vasculitides.

Frontiers in medicine

[Cryoglobulinemic vasculitis].

La Revue du praticien

Journal of translational autoimmunity

Preventive plasmapheresis for rituximab related flare in cryoglobulinemic vasculitis.

Hepatitis B virus-infection related cryoglobulinemic vasculitis. Clinical manifestations and the effect of antiviral therapy: A review of the literature.

Frontiers in oncology

Journal of community hospital internal medicine perspectives

Light Chain Myeloma Precipitating Cryoglobulinemic Vasculitis.

Journal of clinical immunology

COVID-19 and Mixed Cryoglobulinemia Syndrome: Long-Term Survey Study on the Prevalence and Outcome, Vaccine Safety, and Immunogenicity.

A Case of Mixed Type II Cryoglobulinemic Vasculitis Associated With Marginal Zone B-cell Lymphoma.

Case reports in oncological medicine

A Nonseminomatous Germ Cell Tumor Presenting as a Mixed Cryoglobulinemic Vasculitis.

Internal medicine (Tokyo, Japan)

Cryoglobulinemic Vasculitis Associated with Monoclonal Gammopathy of Undetermined Significance Developed after Sustained Virologic Response of Hepatitis C.

Extrahepatic Manifestations of Chronic HBV Infection and the Role of Antiviral Therapy.

Zeitschrift fur Rheumatologie

[Renal manifestations in vasculitides of small and medium-sized vessels].

The Journal of emergency medicine

CRYOGLOBULINEMIC VASCULITIS.

Current dermatology reports

Off-Label Uses of Rituximab in Dermatology.

Management of mixed cryoglobulinemia with rituximab: evidence and consensus-based recommendations from the Italian Study Group of Cryoglobulinemia (GISC).

Therapeutic advances in infectious disease

Cryoglobulinemic vasculitis in two patients with infective endocarditis: a case series.

A Flare of Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis After COVID-19.

Recognizing the true face of noninfectious cryoglobulinemic glomerulonephritis.

Kidney international

Absent or suboptimal response to booster dose of COVID-19 vaccine in patients with autoimmune systemic diseases.

Journal of autoimmunity

Arthritis research & therapy

Cryoglobulinemia in systemic lupus erythematosus: a retrospective study of 213 patients.

Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis.

ACG case reports journal

Journal of community hospital internal medicine perspectives

A Case of Hepatitis C Related Mixed Cryoglobulinemia Syndrome.

Relapse of cryoglobulinemic vasculitis with new-onset severe renal involvement in two patients following mRNA COVID-19 vaccination: A case report.

Medicine

[Cryoglobulinemic vasculitis due to hyperviscosity and cryogel formation as the onset of multiple myeloma. Report of one case].

Revista medica de Chile

Journal of cosmetic dermatology

Livedo racemosa presenting as first manifestation in a patient with multiple myeloma complicated with cryoglobulinemic vasculitis.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Cryoglobulinemia and double-filtration plasmapheresis: Personal experience and literature review.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

Optic Perineuritis in Waldenström Macroglobulinemia-Related Cryoglobulinemic Vasculitis.

B-cell activating factor (BAFF), BAFF promoter and BAFF receptor allelic variants in hepatitis C virus related Cryoglobulinemic Vasculitis and Non-Hodgkin's Lymphoma.

Hematological oncology

Non HCV-Related Mixed Cryoglobulinemic Vasculitis With Biopsy-Proven Renal Involvement: The Effects of Rituximab.

Frontiers in medicine

International journal of dermatology

A rare case of type II cryoglobulinemic vasculitis with renal and pulmonary involvement in a patient with underlying lymphoplasmacytic lymphoma.

Evolution of Cryoglobulinemia in Direct-Acting Antiviral-Treated Asian Hepatitis C Patients With Sustained Virological Responses: A 4-Year Prospective Cohort Study.

Clinical and experimental medicine

The wide spectrum of cryoglobulinemic vasculitis and an overview of therapeutic advancements.

Persistence of Cryoglobulinemic Vasculitis after DAA Induced HCV Cure.

The American journal of gastroenterology

Relapse of Hepatitis C Virus Cryoglobulinemic Vasculitis After Sustained Viral Response After Interferon-Free Direct-Acting Antivirals.

Zeitschrift fur Rheumatologie

[Update on etiopathogenesis of small vessel vasculitis].

Clinical Images: Digital necrosis due to cryoglobulinemic vasculitis secondary to scleroderma.

ACR open rheumatology

Hepatology (Baltimore, Md.)

A prospective study of direct-acting antiviral effectiveness and relapse risk in HCV cryoglobulinemic vasculitis by the Italian PITER cohort.

A Review on Extrahepatic Manifestations of Chronic Hepatitis C Virus Infection and the Impact of Direct-Acting Antiviral Therapy.

Viruses

Kidney international reports

Rituximab-Associated Flare of Cryoglobulinemic Vasculitis.

Impaired immunogenicity to COVID-19 vaccines in autoimmune systemic diseases. High prevalence of non-response in different patients' subgroups.

Journal of autoimmunity

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Unusual Morphological and Automated Hematology Analyzer Features in 3 Cases of B-cell Malignancy-associated Type I Cryoglobulinemic Vasculitis.

Practical Details for the Detection and Interpretation of Cryoglobulins.

Clinical chemistry

Impact of direct acting antivirals (DAA) on neurologic disorders in chronic hepatitis C.

Minerva gastroenterology

Journal of rheumatic diseases

A Case of Overlap Syndrome of Systemic Sclerosis and Cryoglobulinemic Vasculitis With Central Nervous System Involvement.

Predictors of long-term cryoglobulinemic vasculitis outcomes after HCV eradication with direct-acting antivirals in the real-life.

Rapid improvement of psychiatric stigmata after IFN-free treatment in HCV patients with and without cryoglobulinemic vasculitis.

International journal of nephrology and renovascular disease

Noninfectious, Severe Cryoglobulinemic Vasculitis with Renal Involvement - Safety and Efficacy of Long-Term Treatment with Rituximab.

The Journal of dermatology

Cryoglobulinemic vasculitis associated with multicentric Castleman disease.

Hepatitis B Virus-Related Cryoglobulinemic Vasculitis: Review of the Literature and Long-Term Follow-Up Analysis of 18 Patients Treated with Nucleos(t)ide Analogues from the Italian Study Group of Cryoglobulinemia (GISC).

Viruses

World journal of gastroenterology

Immune disorders and rheumatologic manifestations of viral hepatitis.

Journal of cutaneous pathology

Eosinophilic granulomatosis with polyangiitis: Cutaneous clinical and histopathologic differential diagnosis.

Multiple myeloma presenting as cryoglobulinemic vasculitis.

JAAD case reports

Impact of direct acting antivirals on hepatitis C virus-related cryoglobulinemic syndrome.

Minerva gastroenterology

Hepatology (Baltimore, Md.)

Hematological and Genetic Markers in the Rational Approach to Patients With HCV Sustained Virological Response With or Without Persisting Cryoglobulinemic Vasculitis.

[Autoimmunity and autoinflammation in pathogenesis of immunoinflammatory diseases].

Internal and emergency medicine

Diagnosis and management of leukocytoclastic vasculitis.

Corticosteroids are the major contributors to the risk for serious infections in autoimmune disorders with severe renal involvement.

World journal of gastroenterology

Human hepatitis viruses-associated cutaneous and systemic vasculitis.

Severe cryoglobulinemia with cerebral infarction successfully treated with steroid and rituximab: A case report.

Clinical case reports

Wounds : a compendium of clinical research and practice

Negative Pressure Wound Therapy With Instillation and Dwell Time Used to Treat Pyoderma Gangrenosum: A Case Report.

Type II cryoglobulinemic vasculitis in the setting of MALT lymphoma.

BMJ case reports

Going rogue: how autoantibodies become pathogenic.

Kidney international

Advances in experimental medicine and biology

Impact of DAA-Based Regimens on HCV-Related Extra-Hepatic Damage: A Narrative Review.

Mixed Cryoglobulinemia Syndrome (MCS) due to untreated hepatitis B with uncommon presentation: case report and literature review.

BMC rheumatology

Clinics and research in hepatology and gastroenterology

Treatment of hepatitis C virus infection.

Clinics and research in hepatology and gastroenterology

Hepatitis C virus-related vasculitis.

Rheumatologic manifestations of Hepatitis C Virus.

The Relevance of MicroRNAs in the Pathogenesis and Prognosis of HCV-Disease: The Emergent Role of miR-17-92 in Cryoglobulinemic Vasculitis.

Viruses

Cold urticaria - What we know and what we do not know.

Allergy

Case report: a man with untreated rheumatoid arthritis, cryoglobulinemic vasculitis, membranous nephropathy and pulmonary sarcoidosis.

BMC nephrology

Hepatitis C virus-related cryoglobulinemic vasculitis.

The American journal of the medical sciences

Cryoglobulinemic Vasculitis in a Rheumatoid Arthritis Patient.

Current opinion in rheumatology

Cryoglobulinemic vasculitis: pathophysiological mechanisms and diagnosis.

Infective Endocarditis Observed With Cryoglobulinemic Vasculitis.

Journal of investigative medicine high impact case reports

It Is Just a Rash They Said! Acute Skin Manifestation in a Patient With Vasculitis in Rural Hospitals.

Modern rheumatology case reports

Vasculitis in a patient with mixed cryoglobulinemia treated with rituximab biosimilar CT-P10: a case report.

Seminars in arthritis and rheumatism

Cryoglobulinemic vasculitis in primary Sjögren's Syndrome: Clinical presentation, association with lymphoma and comparison with Hepatitis C-related disease.

Internal and emergency medicine

Cryoglobulinemic vasculitis: having giant steps; but there are still unanswered questions.

International journal of dermatology

Cryoglobulinemic vasculitis associated with chronic hepatitis C: a case of skin lesions/purpura in a 49-year-old Caucasian male patient.

Recent news in the treatment of hepatitis B virus-related cryogobulinemic vasculitis.

Hepatitis C virus- related cryoglobulinemic vasculitis: A review of the role of the new direct antiviral agents (DAAs) therapy.

Internal and emergency medicine

Safety and effectiveness of biosimilar of Rituximab CT-P10 in the treatment of cryoglobulinemic vasculitis: the MARBLe study (Mixed cryoglobulinemiA Rituximab BiosimiLar).

Management of Primary Small-Vessel Vasculitis.

Skin therapy letter

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

Good response to cryofiltration in a patient with cryoglobulinemic vasculitis complicated with systemic lupus erythematosus.

Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody.

Cell

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

Epidemiologic Features of Systemic Vasculitides in the Southeast Region of Brazil: Hospital-Based Survey.

Cryoglobulinemic Vasculitis Masquerading as Bilateral Carpal Tunnel Syndrome.

Hepatitis A Virus Infection Associated with Cryoglobulinemic Vasculitis.

Indian pediatrics

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Simultaneous tubular and glomerular involvement with cryoglobulinemia vasculitis in multiple myeloma.

Hepatitis C Virus-Associated Cryoglobulinemic Vasculitis.

Current rheumatology reports

Understanding the Cryoglobulinemias.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada

Leprosy: Challenges in diagnosis.

International journal of hematology

Cryoglobulinemic vasculitis with interruption of ibrutinib therapy for chronic lymphocytic leukemia (CLL).

Best practice & research. Clinical rheumatology

Management of hepatitis B and C infections in rheumatologic disease.

Annals of the rheumatic diseases

Ultrasonographic damages of major salivary glands are associated with cryoglobulinemic vasculitis and lymphoma in primary Sjogren's syndrome: are the ultrasonographic features of the salivary glands new prognostic markers in Sjogren's syndrome?

Expert review of clinical immunology

Treatment of systemic necrotizing vasculitides: recent advances and important clinical considerations.

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

Severe transient left ventricular dysfunction in a patient with Legionella pneumophila pneumonia.

New insights in cryoglobulinemic vasculitis.

Journal of autoimmunity

Type 1 Immunoglobulin M Cryoglobulinemic Vasculitis in a Patient with Chronic Lymphocytic Leukemia and a History of Hepatitis C Virus: Is There a Link?

Expert review of clinical immunology

Predicting lymphoma development in patients with Sjögren's syndrome.

[Cutaneous alterations in vasculitides : Part 2: Special aspects of diseases of large, medium and small vessels].

Der Internist

The remarkable history of the hepatitis C virus.

Microbes and infection

Cryoglobulinemic vasculitis and glomerulonephritis: concerns in clinical practice.

Chinese medical journal

Biomarkers in Vasculitides of the Nervous System.

Frontiers in neurology

[Hepatitis C virus - related cryoglobulinemic vasculitis with renal involvement current possibilities of diagnostic and treatment].

Clinical outcome of HCV-associated cryoglobulinemic glomerulonephritis following treatment with direct acting antiviral agents: a case-based review.

Prevalence of cryoglobulinemia and cryoglobulinemic vasculitis in chronically HCV-infected Brazilian patients.

Annals of hepatology

Journal of internal medicine

Hepatitis B virus-related cryogobulinemic vasculitis. The role of antiviral nucleot(s)ide analogues: a review.

Risk factors of unfavorable prognosis of chronic hepatitis C.

Current opinion in rheumatology

The dilemma of treating hepatitis C virus-associated cryoglobulinemia.

Reviews in cardiovascular medicine

False-positive Troponin I Assay elevation due to occult Mixed Cryoglobulinemic Vasculitis.

Deutsche medizinische Wochenschrift (1946)

[Viral Hepatitis: When to be Considered in Clinical Routine?].

Journal of clinical & cellular immunology

Achieving Sustained Viral Remission in Patients with Chronic HCV Infection and Cryoglobulinemic Vasculitis Does Not Always Correlate with Normalization of the Serologic Markers.

[Hepatitis C facing the challenge of healing].

La Revue du praticien

Overlapping Syndrome of Systemic Scleroderma and Cryoglobulinemic Vasculitis.

The modern therapy of systemic vasculitides: perspectives and challenges.

Efficacy and safety of Rituximab in vasculitic neuropathy: a systematic review of the literature.

Reumatologia clinica

Ver todos os 219 no EuropePMC

Concomitant cryoglobulinemic vasculitis and cold agglutinin disease successfully treated with bortezomib: A case report.

Medicine

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Próxima:Doenças relacionadas

Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Ordenadas pelo número de sintomas em comum.

Vasculite mediada por complexos imunes

35 em comum

ORPHA:156149

Vasculite associada a anticorpos anti-neutrófilo citoplasmáticos (ANCA)

18 em comum

ORPHA:156152

Granulomatose com poliangeíte

17 em comum

ORPHA:900

Lúpus eritematoso sistêmico

16 em comum

ORPHA:536

Granulomatose eosinofílica com poliangeíte

Arterite de células gigantes

ORPHA:183

Vasculite Imunoglobulina A

ORPHA:397

ORPHA:761

Poliangeíte microscópica

Microangiopatia trombótica

ORPHA:727