Raras
Buscar doenças, sintomas, genes...
Vasculite Imunoglobulina A
ORPHA:761CID-10 · D69.0CID-11 · 4A44.92DOENÇA RARA

Vasculite sistêmica por IgA que afeta pequenos vasos. É caracterizada por púrpura cutânea, artrite e envolvimento abdominal e/ou renal.

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Introdução

O que você precisa saber de cara

📋

Vasculite sistêmica por IgA que afeta pequenos vasos. É caracterizada por púrpura cutânea, artrite e envolvimento abdominal e/ou renal.

Pesquisas ativas
3 ensaios
37 total registrados no ClinicalTrials.gov
Publicações científicas
365 artigos
Último publicado: 2026 Apr 16

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
Childhood
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: D69.0
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫘
Rins
4 sintomas
🫃
Digestivo
4 sintomas
🧬
Pele e cabelo
2 sintomas
💪
Músculos
2 sintomas
📏
Crescimento
1 sintomas
🛡️
Imunológico
1 sintomas

+ 16 sintomas em outras categorias

Características mais comuns

90%prev.
Suscetibilidade a hematomas
Muito frequente (99-80%)
90%prev.
Artralgia
Muito frequente (99-80%)
90%prev.
Dor abdominal
Muito frequente (99-80%)
90%prev.
Erupção cutânea
Muito frequente (99-80%)
90%prev.
Hematúria
Muito frequente (99-80%)
90%prev.
Infartos gastrointestinais
Muito frequente (99-80%)
34sintomas
Muito frequente (10)
Frequente (10)
Ocasional (14)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 34 características clínicas mais associadas, ordenadas por frequência.

Suscetibilidade a hematomasBruising susceptibility
Muito frequente (99-80%)90%
ArtralgiaArthralgia
Muito frequente (99-80%)90%
Dor abdominalAbdominal pain
Muito frequente (99-80%)90%
Erupção cutâneaSkin rash
Muito frequente (99-80%)90%
HematúriaHematuria
Muito frequente (99-80%)90%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico365PubMed
Últimos 10 anos200publicações
Pico202561 papers
Linha do tempo
2026Hoje · 2026🧪 1995Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
3Fase 31
·Pré-clínico4
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 5 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Vasculite Imunoglobulina A

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

3 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

37 ensaios clínicos encontrados, 3 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
358 papers (10 anos)
#1

Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.

Current gastroenterology reports2026 Jan 22

This systematic review sought to thoroughly investigate the relationship between Inflammatory Bowel Disease (IBD) and Immunoglobulin A Vasculitis (IgAV), pinpointing both factors that increase risk and those that provide protection, laying the groundwork for future studies on specific treatments approaches to enhance the wellbeing of patients with IgAV and / or IBD. There is a new and quickly expanding body of literature on this subject, indicating a rising interest in it. Recent research has sought to investigate the connection between newly emerged viruses, such as COVID-19, or medications like Anti-Tumor Necrosis Factor Alpha (anti-TNF-α), and the development, progression, and treatment approaches of IgAV in IBD patients, and vice versa. Certain recent research is centered on a particular age groups or the condition of the initial illness. IgAV has been observed for numerous years following the diagnosis of IBD, displaying manifestations in the skin, joints, kidneys, and gastrointestinal tract. IBD encompassing Crohn's disease and ulcerative colitis, and IgAV share immunological overlaps via dysregulated IgA production, genetic loci like HLA-DQA1/DQB1, and environmental triggers such as infections amid gut dysbiosis. IgAV often emerges as an IBD sequela or anti-TNF-α therapy complication, with TNF blockade potentially disrupting B-cell maturation, fostering Gd-IgA1 complexes, and neutrophil-driven inflammation. (31) studies encompassing (83) patients with co-occurring IBD and IgAV, predominantly males (60.2%) and younger individuals with confirmed dual diagnoses (95.2%). Compared to UC, more severe CD phenotypes and extended disease duration correlate with increased IgAV risk. Anti-TNF inhibitors appear to substantially contribute to IgAV onset in IBD patients. Most affected individuals develop IBD initially, followed by IgAV, whereas only a minority experience IBD subsequent to IgAV diagnosis. Ceasing anti-TNF-α therapy post-IgAV diagnosis may lead to IgAV resolution but could also trigger disease recurrence. The study's limited sample size has hindered the researchers from reaching conclusions via a meta-analysis. Additionally, the criteria utilized for IBD diagnosis have displayed inconsistency across all studies. Patients with IBD are at higher risk of developing IgAV, thus a high level of suspicion and prompt diagnostic assessment are crucial. To date, there have been no previous systematic reviews or meta-analyses highlighting a link between IgAV and IBD. Therefore, this systematic review is a pivotal endeavor to elucidate the complex relationship between these conditions, shaping future research in this area.

#2

Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.

JAMA dermatology2026 Feb 01

This case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments.

#3

Analysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.

Clinical pediatrics2026 Mar

Immunoglobulin A vasculitis (IgAV) is a common immune complex-mediated systemic small vessel vasculitis in children. Gastrointestinal (GI) involvement significantly impacts early prognosis and may precede the appearance of purpura, complicating timely diagnosis. We retrospectively analyzed 195 cases of children diagnosed with IgAV from June 2019 to April 2024, among whom 62 cases had GI involvement. Clinical and laboratory data were collected. Children in the IgAV GI involvement group exhibited lower rates of arthritis/arthralgia and significantly higher levels of neutrophil-to-lymphocyte ratio (NLR) (P = .002, OR = 1.455), platelet count (P = .020, OR = 1.005), and uric acid (P = .017, OR = 1.005), with lower immunoglobulin G (IgG) (P = .004, OR = .818) levels. Multivariate analysis identified NLR, platelet count, uric acid, and IgG as independent predictors. The combined model showed good discrimination (area under the curve [AUC] = 0.753) and high specificity (93.2%). Elevated NLR, platelet count, uric acid, and reduced IgG are independent risk factors for GI involvement in pediatric IgAV and may facilitate early risk stratification.

#4

Recurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.

Clinical and experimental pediatrics2026 Jan

Immunoglobulin A vasculitis (IgAV) is a systemic vasculitis characterized by potential recurrence. This study aimed to explore the prevalence of and factors associated with IgAV recurrence. The clinical phenotypes of childhood- and adolescent-onset IgAV were described and compared. This retrospective cohort analysis included patients aged ≤18 years and diagnosed with IgAV treated in a tertiary academic center between January 2010 and December 2022. Recurrence was classified by the reappearance of purpuric/petechiae or other features that reappeared after at least 1 asymptomatic month. The 361 patients with IgAV had a mean age of 7.7±3.9 years; 53.2% of them were female. All patients with IgAV exhibited skin manifestations. Gastrointestinal (GI) and musculoskeletal (MSK) features were observed in 214 (59.3%) and 219 patients (60.7%), respectively. Renal involvement was observed in 82 patients (22.7%). The prevalence of childhood- and adolescent-onset IgAV was 269 (74.5%) and 92 (25.5%), respectively. Patients with childhood-onset IgAV had significant GI manifestations (P=0.01), had MSK features (P=0.002), and required hospitalization (P=0.004). In contrast, patients with adolescent-onset IgAV had significant renal involvement (P<0.001) and required a longer duration of corticosteroids treatment (P<0.001). Of the study population, 119 patients (35.6%) experienced recurrence. During the 12-month follow-up period, 98 patients (27.1%) had recurrent IgAV at a median 1.9 months (interquartile range, 1.2-4.8 months). On the multivariable Cox proportional hazards regression analysis, corticosteroids treatment was significantly associated with IgAV recurrence (hazard ratio, 1.99; 95% confidence interval, 1.266-3.157; P=0.003). Renal involvement was more prevalent in adolescent-onset IgAV, whereas MSK and GI involvement were more common in childhood-onset IgAV. Recurrence was noted in 35.6% of the population. Therefore, vigilant monitoring for recurrence is necessary.

#5

miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.

Rheumatology (Oxford, England)2026 Mar 14

MicroRNAs (miRNAs) play critical roles in regulating immune cell differentiation and maintaining innate and adaptive immune homeostasis. The aim of this study was to determine the mechanisms by which miR-23b-3p modulates crosstalk between innate and adaptive immunity in immunoglobulin A (IgA) vasculitis (IgAV) and to evaluate its therapeutic potential. An IgAV rat model and in vitro cell culture systems were established to assess the effects of miR-23b-3p on dendritic cell (DC) maturation and function via Toll-like receptor 4 (TLR4) signalling and to determine the subsequent impact on T follicular helper (Tfh) cell differentiation mediated by cytokine secretion. IgAV rats exhibited significantly increased TLR4 expression in peripheral blood mononuclear cells and spleen tissue, accompanied by reduced miR-23b-3p expression. Mechanistic analyses demonstrated that miR-23b-3p directly targeted TLR4 to suppress its expression. In vivo overexpression of miR-23b-3p ameliorated IgAV manifestations, as evidenced by reduced TLR4 expression on DCs, diminished Tfh cell differentiation, and decreased serum levels of IgA, interleukin (IL)-6, and IL-12. Notably, TLR4 silencing reversed miR-23b-3p inhibitor-induced DC hyperactivation and aberrant Tfh cell differentiation. miR-23b-3p regulates DC maturation and function and subsequent Tfh differentiation in a TLR4-dependent manner. miR-23b-3p deficiency aggravates IgAV by promoting pathogenic DC-Tfh axis activation, whereas restoration of miR-23b-3p expression attenuates immune dysregulation, suggesting a potential therapeutic strategy for IgAV.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC215 artigos no totalmostrando 199

2026

miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.

Rheumatology (Oxford, England)
2026

Serum SCUBE1 and SCUBE2 Levels in Children with Immunoglobulin A Vasculitis: An Exploratory Study.

Rheumatology and therapy
2026

Demographic, Clinical, and Laboratory Characteristics of Pediatric IgA Vasculitis: A Retrospective Five-Year Single-Center Experience.

Journal of clinical medicine
2026

Malignant renovascular hypertension consequent to IgA vasculitis in a young male patient: a case report.

Journal of medical case reports
2026

Renal Shear Wave Elastography for Differentiating Vasculitic and Non-Vasculitic Acute Kidney Injury.

Journal of clinical medicine
2026

First case of IgA vasculitis atypically presenting as recurrent gastroenteritis from Nepal: a case report and review of the literature.

Annals of medicine and surgery (2012)
2026

[More than just purpura-Immunoglobulin A vasculitis in adulthood].

Innere Medizin (Heidelberg, Germany)
2026

Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.

Current gastroenterology reports
2026

Recurrent diffuse alveolar hemorrhage in Immunoglobulin A vasculitis.

Respiratory medicine case reports
2026

Painful subcutaneous edema is associated with early age at disease onset in Immunoglobulin A vasculitis patients: A multicenter study.

Clinics (Sao Paulo, Brazil)
2026

Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.

JAMA dermatology
2025

Systemic and dermatological findings of immunoglobulin A vasculitis in a black child: A case report.

World journal of clinical cases
2025

IgA Vasculitis With Nephritis Following Controlled Ovarian Stimulation and Oocyte Donation.

Cureus
2025

Suspected Alcohol-Induced Immunoglobulin A Vasculitis: A Case Series and Review of the Literature.

Case reports in dermatology
2025

Immunoglobulin A Vasculitis Associated Terminal Ileitis Mimicking Inflammatory Bowel Disease: Diagnostic Challenge and Therapeutic Role of Steroids - A Case Report.

Case reports in dermatology
2025

Role of red cell distribution width, tumor necrosis factor-alpha, and interleukin-6 in immunoglobulin a vasculitis nephritis among Tibetan children in high-altitude areas.

BMC pediatrics
2026

Ustekinumab-induced Henoch-Schönlein purpura in Crohn's disease: a case report and literature review.

Intestinal research
2025

The role of NFKB1 and NFKBIA in immunoglobulin A vasculitis.

Frontiers in immunology
2025

Case Report: Severe gastrointestinal complications in adult IgA vasculitis: a fatal case of acute esophageal necrosis.

Frontiers in immunology
2026

Analysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.

Clinical pediatrics
2025

Immunoglobulin A vasculitis with aneurysmal subarachnoid hemorrhage in an adult.

JAAD case reports
2026

Pathophysiology of glomerulonephritis in autoimmune diseases.

Current opinion in rheumatology
2026

Recurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.

Clinical and experimental pediatrics
2025

Efficacy and safety of telitacicept in children with IgA vasculitis and IgA vasculitis nephritis: a single-center retrospective study.

Pediatric rheumatology online journal
2025

Some novel causes and clinical characteristics of reversible splenial lesion syndrome- found in children.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2026

Risk factors for recurrence or relapse after a first episode of adult IgA vasculitis: A multicenter retrospective study.

Journal of the American Academy of Dermatology
2025

Efficacy and Safety of Telitacicept in Adult IgA Vasculitis Nephropathy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2025

Serum elafin levels in patients with IgA vasculitis: a prospective case-control study.

Pediatric rheumatology online journal
2025

Biomarker research for Henoch-Schönlein purpura nephritis based on "omics" techniques.

Frontiers in medicine
2025

Guidelines for the diagnosis and management of childhood immunoglobulin A vasculitis.

World journal of pediatrics : WJP
2025

Gastrointestinal bleeding as an early presentation of the pediatric granulomatosis with polyangiitis: A rare report.

SAGE open medical case reports
2025

KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV).

Kidney international
2025

Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV).

Kidney international
2025

Atypical presentation of immunoglobulin A vasculitis mimicking acute appendicitis in a pediatric patient: a case report.

Future science OA
2025

[The Value of Thrombus Biomarkers for Assessing the Progression of Immunoglobulin A Vasculitis in Children].

Zhongguo shi yan xue ye xue za zhi
2025

Evaluation of rheumatic causes underlying childhood-onset arthritis.

Turkish journal of medical sciences
2025

Relief of Suspected IgA Vasculitis-Associated Enterocolitis Manifested as Severe Diarrhea and Hypoalbuminemia Treated With Glucocorticoid Therapy and Administration of Fibrogammin® (Purified Coagulation Factor XIII Concentrate): A Case Report.

Cureus
2025

Vasculitis as an indicator of disease severity in familial Mediterranean fever.

Frontiers in immunology
2025

Immunoglobulin A Vasculitis Following COVID-19 Infection in an Adolescent Girl.

Oman medical journal
2025

Risk factors associated with renal injury in patients initially diagnosed with IgA vasculitis.

Frontiers in pediatrics
2025

Epidemiology, clinical features and outcomes of patients with kidney biopsy proven IgA vasculitis in Auckland and Northland, Aotearoa, New Zealand presenting between 2003-2020.

BMC nephrology
2025

Exploring the Anti-Inflammatory and Anti-NET Properties of Zidian Zhenxiao Granule in IgA Vasculitis: A Network Pharmacology and Proteomic Study.

Journal of inflammation research
2025

Serum IgE and IgA Levels in Pediatric Henoch-Schönlein Purpura: Clinical Characteristics and Immunological Correlations in the Context of Infectious Diseases-A Five-Year Retrospective Analysis.

International journal of molecular sciences
2025

Pediatric Immunoglobulin A Vasculitis: Impact of Mediterranean Fever Gene Variants on Clinical Course and Inflammatory Markers.

Turkish archives of pediatrics
2025

Comprehensive analysis of the clinical and pathological features and prognoses of children with immunoglobulin A vasculitis nephritis with immunoglobulin M deposits in glomeruli.

Kidney research and clinical practice
2025

Patients With IgA Vasculitis and Kawasaki Disease Show Dysregulated Interferon Signature.

International journal of rheumatic diseases
2025

The Importance of Early Steroid Use in IgA Vasculitis Complicated by Disseminated Intravascular Coagulation in an Adult.

Cureus
2025

Mycophenolate Mofetil as a Therapeutic Option in Refractory Immunoglobulin A Vasculitis: A Report of Two Atypical Cases.

Cureus
2025

Skin Deep: A Narrative Case Series and Review of Cutaneous Vasculitis and Possible Doppelgängers.

The American journal of medicine
2025

Immunoglobulin A vasculitis and pustular psoriasis precipitated by Tawon Liar: a case report.

Journal of medical case reports
2025

A case and literature review of axial spondyloarthritis and immunoglobulin A vasculitis: Rare association or under-recognized?

SAGE open medical case reports
2025

Adult-Onset Immunoglobulin A Vasculitis (IgAV) Presenting in a Middle-Aged Indian Male Patient.

Cureus
2025

NETs in the spotlight: exploring NETosis markers for tracking disease activity in IgA vasculitis.

Rheumatology (Oxford, England)
2025

Laboratory Findings and Clinical Features in IgA Vasculitis: Identifying Predictors of Kidney Involvement and Disease Relapse in Pediatric Patients.

Journal of clinical medicine
2025

Immunoglobulin a vasculitis with central nervous system involvement: analysis of 10 cases.

Clinical and experimental medicine
2025

Tph cells are expanded in IgA vasculitis nephritis.

Molecular immunology
2025

A case-based review of IgA vasculitis complicated with gastrointestinal infections: insights from a norovirus-associated case in an adolescent.

Rheumatology international
2025

Efficacy and Safety of Telitacicept as an Add-On Therapy for Refractory Immunoglobulin A Nephropathy or Immunoglobulin A Vasculitis Nephropathy in Children.

Kidney international reports
2025

Telitacicept as a BAFF/APRIL dual inhibitor: efficacy and safety in reducing proteinuria for refractory childhood IgA vasculitis nephritis.

Pediatric nephrology (Berlin, Germany)
2025

Assessment of renal resistive index measurement in children with immunoglobulin A vasculitis.

Reumatologia
2025

Differential gut microbiota and inflammatory cytokines contribute to IgA vasculitis.

Clinical and experimental rheumatology
2025

How familial Mediterranean fever affects the characteristics of immunoglobulin a vasculitis in pediatric patients at the time of diagnosis?

European journal of pediatrics
2025

A case report of Henoch-Schönlein purpura in the elderly complicated by multisystem involvement.

Medicine
2025

Unilateral Cheek Edema in a Child with Immunoglobulin A Vasculitis.

Indian pediatrics
2025

Patterned eruption following fishnet stocking use.

JAAD case reports
2025

An Atypical Presentation of Henoch-Schönlein Purpura With Features of Acute Hemorrhagic Edema of Infancy and Koebnerization: A Case Report.

Cureus
2024

Relationship between IgA vasculitis and prothrombotic risk factors: A prospective, case-control study.

Archives of rheumatology
2025

Ustekinumab-Induced Vasculitis in a Patient With Crohn's Disease.

ACG case reports journal
2025

Severe colitis in a patient with immunoglobulin A vasculitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
2025

Tonsillectomy in Immunoglobulin A vasculitis with nephritis: case series.

CEN case reports
2025

The extent of intestinal involvement is closely related to the severity of IgAV: a risk stratification study based on CT.

Annals of medicine
2025

Clinical features of abdominal immunoglobulin A vasculitis in adults: a single-center retrospective study.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
2025

[Clinicopathological significance and prognostic value of serum 25-hydroxyvitamin D3 level in children with IgA vasculitis nephritis].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2025

Factors associated with renal involvement in adult immunoglobulin a vasculitis: what is it?

Postgraduate medicine
2024

[Clinical and pathological features of children with immunoglobulin A vasculitis with nephritis accompanied by different proportions of crescent formation].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2025

Epidemiology of systemic vasculitis.

Current opinion in rheumatology
2024

Immunoglobulin A Vasculitis Nephritis in an Adult.

Cureus
2024

Exploring the predictive factors in the gastrointestinal involvement of patients with immunoglobulin A vasculitis.

The Turkish journal of pediatrics
2024

Characteristics of cutaneous manifestations in immunoglobulin a vasculitis and their relationships with system involvement and treatment needs.

European journal of pediatrics
2025

Can the affected intestinal segment visualized on abdominal ultrasound predict gastrointestinal tract bleeding in immunoglobulin A vasculitis?

Modern rheumatology
2024

Gastrointestinal manifestations and pathogenesis in childhood immunoglobulin A vasculitis.

Frontiers in pediatrics
2024

Delayed diagnosis of angioimmunoblast T-cell lymphoma presenting with immunoglobulin a vasculitis.

Renal failure
2024

Risk Factors for Renal Involvement in Childhood Henoch-Schonlein Purpura (IgA Vasculitis).

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
2025

Immunoglobulin A vasculitis with Koebner phenomenon and renal involvement induced by antitumor necrosis factor α therapy in the treatment of rheumatoid arthritis.

Polish archives of internal medicine
2024

Association of Childhood IgA Vasculitis With Allergic Rhinitis and Chronic Rhinosinusitis.

Kidney international reports
2024

Blood soluble CD89-IgA complex may be a potential biomarker for predicting multi-organ involvement, especially renal involvement in children with immunoglobulin A vasculitis.

International immunopharmacology
2024

Amelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17 cells.

Journal of autoimmunity
2024

Case report: Nephritic/nephrotic syndrome in a child with immunoglobulin A vasculitis.

International journal of rheumatic diseases
2024

Explore the Value of Multi-Parameter MRI in Non-Invasive Assessment of Prognostic Risk and Oxford Classification in Children with IgAN or IgAVN.

Bioengineering (Basel, Switzerland)
2025

Immunoglobulin A vasculitis with periorbital edema and severe renal involvement: A case report.

Pediatric dermatology
2024

Comparison of different doses of Tripterygium glycosides treating in IgA vasculitis nephritis: A Bayesian network meta-analysis.

Heliyon
2024

Fasciitis as a Complication of IgA Vasculitis.

Cureus
2024

An Unusual Case of Abdominal Pain in a Geriatric Man.

The Journal of emergency medicine
2024

A Case Series of Unusual IgA Vasculitis.

HCA healthcare journal of medicine
2024

An Unusual Presentation of Propylthiouracil-Induced Immunoglobulin A Vasculitis With Positive Anti-proteinase-3 and Anti-myeloperoxidase Antibodies.

Cureus
2024

Clinical characteristics and risk factors for kidney involvement in children with immunoglobulin A vasculitis.

Pediatrics international : official journal of the Japan Pediatric Society
2024

Immunoglobulin A vasculitis: The clinical features and pathophysiology.

The Kaohsiung journal of medical sciences
2023

Reporting the clinical spectrum of children with IgAV in a retrospective 24-year cohort: Influences of age and sex on clinical presentation.

Turkish journal of medical sciences
2024

Immunoglobulin A Vasculitis After Initiation of Treatment for Tuberculous Pleurisy: A Case Report and Literature Review.

Cureus
2024

Henoch-Schönlein purpura following mRNA COVID-19 vaccination: a case report.

Clinical and experimental vaccine research
2024

The efficacy and safety of tacrolimus in treating refractory IgA vasculitis nephritis: a single-center retrospective study on 16 cases.

Clinical kidney journal
2024

Annular Leukocytoclastic Vasculitis: A New Feature of IgA Vasculitis.

European journal of case reports in internal medicine
2024

A Rare Case of Immunoglobulin A Vasculitis in an Adult Male.

Cureus
2024

Deregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers.

Arthritis research &amp; therapy
2024

Single-cell RNA sequencing of pediatric renal tissues revealed the potential relationship between immunoglobulin A nephropathy and immunoglobulin A vasculitis with nephritis.

Clinical and translational medicine
2024

Extracellular CIRP co-stimulated T cells through IL6R/STAT3 in pediatric IgA vasculitis.

Biochimica et biophysica acta. Molecular basis of disease
2024

Ang-1, Ang-2, and Tie2 are diagnostic biomarkers for Henoch-Schönlein purpura and pediatric-onset systemic lupus erythematous.

Open life sciences
2024

Severe immunoglobulin A vasculitis with refractory gastrointestinal involvement in an adult patient successfully treated with plasma exchange.

Scandinavian journal of rheumatology
2024

[Urinary protein and renal pathological features in children with immunoglobulin A vasculitis with nephritis and hypercoagulability].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2024

Taxonomic and functional shifts of gut microbiome in immunoglobulin A vasculitis children and their mothers.

Frontiers in pediatrics
2024

Epidemiology and clinical characteristics of biopsy-confirmed adult-onset IgA vasculitis in southern Sweden.

RMD open
2023

ASSOCIATION BETWEEN HIGH MOBILITY GROUP BOX 1 PROTEIN GENE (rs41369348) POLYMORPHISM AND IMMUNOGLOBULIN A VASCULITIS IN CHILDREN.

Acta clinica Croatica
2024

Clinical characteristics and risk factors of cardiac involvement in pediatric immunoglobulin A vasculitis: A 7-year retrospective study from a single tertiary medical center.

European journal of pediatrics
2024

Worldwide Distribution and Extracutaneous Manifestations of Henoch-Schönlein Purpura in Adults: Narrative Review.

JMIR dermatology
2024

Immunoglobulin A Vasculitis With Intussusception in Children.

The American surgeon
2024

[Immunoglobulin A vasculitis].

Innere Medizin (Heidelberg, Germany)
2024

Successful rituximab therapy in adult-onset IgA vasculitis with diffuse alveolar hemorrhage and renal failure: a case report.

AME case reports
2024

Outcome of immunosuppression in children with IgA vasculitis-related nephritis.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
2024

Possible Threats of IgA Vasculitis in Children: One Center Experience.

Acta medica Lituanica
2023

Does age at disease onset affect the clinical presentation and outcome in children with immunoglobulin A vasculitis?

Archives of rheumatology
2023

Rituximab as possible therapy in TNF inhibitor-induced IgA vasculitis with severe renal involvement.

BMC nephrology
2023

[Research advances in the etiology and pathogenesis of immunoglobulin A vasculitis].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2023

Analysis of IL-1β, TGF-β, IL-5, ACE, PTPN22 gene polymorphisms, and gene expression levels in Turkish children with IgA vasculitis.

Molecular biology reports
2024

Immunoglobulin A vasculitis involving the duodenum and jejunum.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
2023

[Association between vaccination and the risk of immunoglobulin A vasculitis in children].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2024

Renal Medullary Angiitis Associated with Cutaneous Leukocytoclastic Vasculitis.

Internal medicine (Tokyo, Japan)
2024

Immunoglobulin-A vasculitis manifesting as edema in the scalp, face, and sternocleidomastoid muscle.

International journal of rheumatic diseases
2023

Immunoglobulin A Vasculitis as a Sign of Recurrence of Lingual Cancer.

Journal of clinical rheumatology : practical reports on rheumatic &amp; musculoskeletal diseases
2023

Immunoglobulin A Vasculitis Following ChadOx1 nCoV-19/AZD1222 (AstraZeneca COVID-19 Vaccine) Vaccination.

Annals of dermatology
2023

Immunoglobulin A vasculitis nephritis: Current understanding of pathogenesis and treatment.

World journal of nephrology
2023

Mucosal Immune Defence Gene Polymorphisms as Relevant Players in the Pathogenesis of IgA Vasculitis?

International journal of molecular sciences
2023

Atypical Immunoglobulin A Vasculitis in a Pediatric Patient With Ulcerative Colitis.

ACG case reports journal
2023

Association between Factor XIII Activity and Clinical Course in Pediatric Patients with Immunoglobulin A Vasculitis.

The Kobe journal of medical sciences
2023

Renal pathology in adult and paediatric population of Japan: review of the Japan renal biopsy registry database from 2007 to 2017.

Journal of nephrology
2024

Pregnancy outcome in patients with a medical history of immunoglobulin A vasculitis: a case-control study.

Scandinavian journal of rheumatology
2023

AZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF.

Molecular medicine reports
2023

Henoch-Schönlein purpura with antecedent allergic diseases in a 4-year-old child: a case report.

Annals of medicine and surgery (2012)
2023

Immunoglobulin A Vasculitis: Contemplating Treatment for Gastrointestinal Involvement.

Cureus
2023

[Immunoglobulin A vasculitis (IgAV)].

Zeitschrift fur Rheumatologie
2023

Bowman's capsule rupture and the Oxford MEST-C score in adult patients with Immunoglobulin a vasculitis nephritis: a single center experience.

Annals of medicine
2023

Effect of Nonimmune Factors on Renal Prognosis in Adult IgA Vasculitis With Nephritis: A Long-Term Retrospective Cohort Study.

The Journal of rheumatology
2023

Extensive Palpable Purpura Preceding Renal Dysfunction in Immunoglobulin A Vasculitis Due to Coronavirus-19 Infection.

The American journal of medicine
2023

Cyclosporin A in combination with corticosteroids as a treatment for immunoglobulin A vasculitis nephritis in children.

Minerva pediatrics
2023

Immunoglobulin a vasculitis with testicular/epididymal involvement in children: A retrospective study of a ten-year period.

Frontiers in pediatrics
2023

Pathophysiology and clinical manifestations of immune complex vasculitides.

Frontiers in medicine
2023

IgA Vasculitis in Japanese Patients Harboring MEFV Mutations: A Case Report and Review of the Literature.

Cureus
2023

Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review.

Journal of autoimmunity
2023

Adult-Onset Immunoglobulin A Vasculitis Following Hemodialysis Treatment: An Unusual Presentation.

Cureus
2023

Association of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio with Gastrointestinal Involvement of Immunoglobulin a Vasculitis.

Clinical, cosmetic and investigational dermatology
2023

Intussusception as a rare manifestation of immunoglobulin A vasculitis: Risk factors and treatment.

Journal of paediatrics and child health
2023

Immunoglobulin A vasculitis presenting as bilateral upper eyelid erythema: A case report and review of literature.

Pediatric dermatology
2023

Successful treatment of rituximab in a steroid-dependent immunoglobulin A vasculitis patient with gastrointestinal involvement: a case report.

Scandinavian journal of rheumatology
2022

Landscape of intestinal microbiota in patients with IgA nephropathy, IgA vasculitis and Kawasaki disease.

Frontiers in cellular and infection microbiology
2023

Adult invasive meningococcal disease caused by Neisseria meningitidis classified as serogroup B and sequence type 15947.

The Journal of dermatology
2022

Gastrointestinal Bleeding Induced by Immunoglobulin A Vasculitis on Post-Mild COVID-19 Patients.

Cureus
2023

Venous sinus thrombosis in a case of immunoglobulin A vasculitis and a systemic review of literature.

International journal of rheumatic diseases
2023

The spectrum and changes of biopsy-proven kidney diseases in Chinese children.

Journal of nephrology
2023

Intravenous immunoglobulin therapy in immunoglobulin A vasculitis with gastrointestinal tract involvement.

Clinical and experimental medicine
2022

Effects of diurnal variation of bile acids by meal on cyclosporine A absorption.

Pediatrics international : official journal of the Japan Pediatric Society
2023

Preadolescent-versus adolescent-onset immunoglobulin A vasculitis: The impact of age on prognosis.

Pediatrics international : official journal of the Japan Pediatric Society
2023

Association of human leukocyte antigen with IgA vasculitis with nephritis in Japanese children.

Pediatrics international : official journal of the Japan Pediatric Society
2022

50 Years Ago in TheJournalofPediatrics: Are We Any Better at Understanding the Prognosis of Immunoglobulin A Vasculitis Nephritis?

The Journal of pediatrics
2023

Immunoglobulin A vasculitis in a child: Secondary to COVID-19 or cystic fibrosis?

Pediatric pulmonology
2022

COVID-19 associated immunoglobulin A vasculitis in an adult.

JAAD case reports
2022

IgA vasculitis update: Epidemiology, pathogenesis, and biomarkers.

Frontiers in immunology
2022

Serum pepsinogen cut-off values in Helicobacter pylori-infected children.

Pediatrics international : official journal of the Japan Pediatric Society
2022

Refractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report.

Cureus
2022

Immunoglobulin A Vasculitis Following COVID-19: A French Multicenter Case Series.

The Journal of rheumatology
2022

IgA Vasculitis: Influence of CD40, BLK and BANK1 Gene Polymorphisms.

Journal of clinical medicine
2023

Urinary complement proteins are increased in children with IgA vasculitis (Henoch-Schönlein purpura) nephritis.

Pediatric nephrology (Berlin, Germany)
2023

Acute pancreatitis associated with immunoglobulin A vasculitis: report of fifteen cases.

Clinical rheumatology
2022

Immunoglobulin A vasculitis induced by atypical pneumonia infection with Chlamydophila pneumonia.

IDCases
2022

Immunoglobulin A Vasculitis Associated With COVID-19 Infection Successfully Treated With Corticosteroid Regimen Without Relapse.

Cureus
2023

Tubulointerstitial B-cell infiltration and tertiary lymphoid tissue in adult-onset immunoglobulin A vasculitis with nephritis.

International urology and nephrology
2022

Coronavirus disease 2019, vaccination against coronavirus and immunoglobulin A-mediated diseases: systematic literature review.

Journal of autoimmunity
2023

Clinical features of paediatric immunoglobulin A vasculitis patients with scrotal involvement.

Modern rheumatology
2022

A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient.

Cureus
2022

Risk assessment and prediction model of renal damage in childhood immunoglobulin A vasculitis.

Frontiers in pediatrics
2022

Dapsone for Refractory Gastrointestinal Symptoms in Children With Immunoglobulin A Vasculitis.

Pediatrics
2022

Individualized medication based on pharmacogenomics and treatment progress in children with IgAV nephritis.

Frontiers in pharmacology
2022

Relevance of Intestinal Microbiota in Immunoglobulin A Vasculitis With Abdominal Involvement.

Frontiers in pediatrics
2022

Steroid-resistant peripheral neuropathy in a child: a rare finding in immunoglobulin a vasculitis.

The Turkish journal of pediatrics
2023

Association of Pediatric Vasculitis Activity Score with immunoglobulin A vasculitis with nephritis.

Pediatric nephrology (Berlin, Germany)
2022

Mean platelet volume may not play a role in the differential diagnosis of immunoglobulin A vasculitis and appendicitis in children.

Updates in surgery
2022

Findings on the Relationship Between Intestinal Microbiome and Vasculitis.

Frontiers in cellular and infection microbiology
2022

An Emerging Role for Neutrophil Extracellular Traps in IgA Vasculitis: A Mini-Review.

Frontiers in immunology
2022

Adjunctive treatment with infliximab in pediatric immunoglobulin A (IgA) vasculitis: A case report.

Pediatric dermatology
2022

Blood routine examination: a simple way for differential diagnosis of immunoglobulin A vasculitis with abdominal involvement and appendicitis in children.

Updates in surgery
2022

COVID-19 and New Onset IgA Vasculitis: A Systematic Review of Case Reports.

Journal of emergency nursing
2022

Retroperitoneal fibrosis requiring prompt nephrostomy in a case with immunoglobulin A vasculitis.

Scandinavian journal of rheumatology
2022

Lumbar swelling and migrating edema in 3- and 4-year-old boys.

SAGE open medical case reports
2022

Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis.

Children (Basel, Switzerland)
2022

High levels of platelet-to-lymphocyte ratio may predict reduced risk of end stage of renal disease in Chinese patients with MPO-ANCA associated vasculitis.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2022

Adult Onset Immunoglobulin A (IgA) Vasculitis Secondary to Group A Streptococcus Infection.

Cureus
2022

Adult-Onset Immunoglobulin A Vasculitis With Renal Involvement.

Cureus
2022

Sertraline-Associated Immunoglobulin A Vasculitis.

American journal of therapeutics
2022

Genome-wide association study of 7661 Chinese Han individuals and fine-mapping major histocompatibility complex identifies HLA-DRB1 as associated with IgA vasculitis.

Journal of clinical laboratory analysis
2022

An Immunoglobulin A Vasculitis Case Without Skin Symptoms Complicated With Severe Abdominal Symptoms.

Journal of medical cases
2022

Blood transthyretin for predicting immunoglobulin A vasculitis nephritis outcome in children.

International immunopharmacology
Ver todos os 215 no EuropePMC

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.
    Current gastroenterology reports· 2026· PMID 41569327mais citado
  2. Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.
    JAMA dermatology· 2026· PMID 41499136mais citado
  3. Analysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.
    Clinical pediatrics· 2026· PMID 41194696mais citado
  4. Recurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.
    Clinical and experimental pediatrics· 2026· PMID 41125223mais citado
  5. miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.
    Rheumatology (Oxford, England)· 2026· PMID 41830436mais citado
  6. Colchicine for Skin Involvement in Immunoglobulin A Vasculitis: A Single-Center Case Series and Review of the Literature.
    J Cutan Med Surg· 2026· PMID 41989061recente
  7. Predictors of the late recurrences of immunoglobulin A vasculitis due to clinical and laboratory features in children.
    Mod Rheumatol· 2026· PMID 41967493recente
  8. Gastrointestinal Involvement in Adult IgA Vasculitis: A Comprehensive Review.
    Cureus· 2026· PMID 41939557recente
  9. Serum SCUBE1 and SCUBE2 Levels in Children with Immunoglobulin A Vasculitis: An Exploratory Study.
    Rheumatol Ther· 2026· PMID 41792387recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:761(Orphanet)
  2. MONDO:0019167(MONDO)
  3. GARD:8204(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q1035319(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Vasculite Imunoglobulina A
Compêndio · Raras BR

Vasculite Imunoglobulina A

ORPHA:761 · MONDO:0019167
Prevalência
Unknown
Herança
Not applicable
CID-10
D69.0 · Púrpura alérgica
CID-11
Ensaios
3 ativos
Início
Childhood
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0034152
EuropePMC
Wikidata
Wikipedia
Papers 10a
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