Vasculite sistêmica por IgA que afeta pequenos vasos. É caracterizada por púrpura cutânea, artrite e envolvimento abdominal e/ou renal.
Introdução
O que você precisa saber de cara
Vasculite sistêmica por IgA que afeta pequenos vasos. É caracterizada por púrpura cutânea, artrite e envolvimento abdominal e/ou renal.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 16 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 34 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Vasculite Imunoglobulina A
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Outros ensaios clínicos
37 ensaios clínicos encontrados, 3 ativos.
Publicações mais relevantes
Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.
This systematic review sought to thoroughly investigate the relationship between Inflammatory Bowel Disease (IBD) and Immunoglobulin A Vasculitis (IgAV), pinpointing both factors that increase risk and those that provide protection, laying the groundwork for future studies on specific treatments approaches to enhance the wellbeing of patients with IgAV and / or IBD. There is a new and quickly expanding body of literature on this subject, indicating a rising interest in it. Recent research has sought to investigate the connection between newly emerged viruses, such as COVID-19, or medications like Anti-Tumor Necrosis Factor Alpha (anti-TNF-α), and the development, progression, and treatment approaches of IgAV in IBD patients, and vice versa. Certain recent research is centered on a particular age groups or the condition of the initial illness. IgAV has been observed for numerous years following the diagnosis of IBD, displaying manifestations in the skin, joints, kidneys, and gastrointestinal tract. IBD encompassing Crohn's disease and ulcerative colitis, and IgAV share immunological overlaps via dysregulated IgA production, genetic loci like HLA-DQA1/DQB1, and environmental triggers such as infections amid gut dysbiosis. IgAV often emerges as an IBD sequela or anti-TNF-α therapy complication, with TNF blockade potentially disrupting B-cell maturation, fostering Gd-IgA1 complexes, and neutrophil-driven inflammation. (31) studies encompassing (83) patients with co-occurring IBD and IgAV, predominantly males (60.2%) and younger individuals with confirmed dual diagnoses (95.2%). Compared to UC, more severe CD phenotypes and extended disease duration correlate with increased IgAV risk. Anti-TNF inhibitors appear to substantially contribute to IgAV onset in IBD patients. Most affected individuals develop IBD initially, followed by IgAV, whereas only a minority experience IBD subsequent to IgAV diagnosis. Ceasing anti-TNF-α therapy post-IgAV diagnosis may lead to IgAV resolution but could also trigger disease recurrence. The study's limited sample size has hindered the researchers from reaching conclusions via a meta-analysis. Additionally, the criteria utilized for IBD diagnosis have displayed inconsistency across all studies. Patients with IBD are at higher risk of developing IgAV, thus a high level of suspicion and prompt diagnostic assessment are crucial. To date, there have been no previous systematic reviews or meta-analyses highlighting a link between IgAV and IBD. Therefore, this systematic review is a pivotal endeavor to elucidate the complex relationship between these conditions, shaping future research in this area.
Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.
This case report describes a patient in his 50s with immunoglobulin A vasculitis with monoclonal B-cell lymphocytosis who was successfully treated with zanubrutinib after failure of multiple treatments.
Analysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.
Immunoglobulin A vasculitis (IgAV) is a common immune complex-mediated systemic small vessel vasculitis in children. Gastrointestinal (GI) involvement significantly impacts early prognosis and may precede the appearance of purpura, complicating timely diagnosis. We retrospectively analyzed 195 cases of children diagnosed with IgAV from June 2019 to April 2024, among whom 62 cases had GI involvement. Clinical and laboratory data were collected. Children in the IgAV GI involvement group exhibited lower rates of arthritis/arthralgia and significantly higher levels of neutrophil-to-lymphocyte ratio (NLR) (P = .002, OR = 1.455), platelet count (P = .020, OR = 1.005), and uric acid (P = .017, OR = 1.005), with lower immunoglobulin G (IgG) (P = .004, OR = .818) levels. Multivariate analysis identified NLR, platelet count, uric acid, and IgG as independent predictors. The combined model showed good discrimination (area under the curve [AUC] = 0.753) and high specificity (93.2%). Elevated NLR, platelet count, uric acid, and reduced IgG are independent risk factors for GI involvement in pediatric IgAV and may facilitate early risk stratification.
Recurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.
Immunoglobulin A vasculitis (IgAV) is a systemic vasculitis characterized by potential recurrence. This study aimed to explore the prevalence of and factors associated with IgAV recurrence. The clinical phenotypes of childhood- and adolescent-onset IgAV were described and compared. This retrospective cohort analysis included patients aged ≤18 years and diagnosed with IgAV treated in a tertiary academic center between January 2010 and December 2022. Recurrence was classified by the reappearance of purpuric/petechiae or other features that reappeared after at least 1 asymptomatic month. The 361 patients with IgAV had a mean age of 7.7±3.9 years; 53.2% of them were female. All patients with IgAV exhibited skin manifestations. Gastrointestinal (GI) and musculoskeletal (MSK) features were observed in 214 (59.3%) and 219 patients (60.7%), respectively. Renal involvement was observed in 82 patients (22.7%). The prevalence of childhood- and adolescent-onset IgAV was 269 (74.5%) and 92 (25.5%), respectively. Patients with childhood-onset IgAV had significant GI manifestations (P=0.01), had MSK features (P=0.002), and required hospitalization (P=0.004). In contrast, patients with adolescent-onset IgAV had significant renal involvement (P<0.001) and required a longer duration of corticosteroids treatment (P<0.001). Of the study population, 119 patients (35.6%) experienced recurrence. During the 12-month follow-up period, 98 patients (27.1%) had recurrent IgAV at a median 1.9 months (interquartile range, 1.2-4.8 months). On the multivariable Cox proportional hazards regression analysis, corticosteroids treatment was significantly associated with IgAV recurrence (hazard ratio, 1.99; 95% confidence interval, 1.266-3.157; P=0.003). Renal involvement was more prevalent in adolescent-onset IgAV, whereas MSK and GI involvement were more common in childhood-onset IgAV. Recurrence was noted in 35.6% of the population. Therefore, vigilant monitoring for recurrence is necessary.
miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.
MicroRNAs (miRNAs) play critical roles in regulating immune cell differentiation and maintaining innate and adaptive immune homeostasis. The aim of this study was to determine the mechanisms by which miR-23b-3p modulates crosstalk between innate and adaptive immunity in immunoglobulin A (IgA) vasculitis (IgAV) and to evaluate its therapeutic potential. An IgAV rat model and in vitro cell culture systems were established to assess the effects of miR-23b-3p on dendritic cell (DC) maturation and function via Toll-like receptor 4 (TLR4) signalling and to determine the subsequent impact on T follicular helper (Tfh) cell differentiation mediated by cytokine secretion. IgAV rats exhibited significantly increased TLR4 expression in peripheral blood mononuclear cells and spleen tissue, accompanied by reduced miR-23b-3p expression. Mechanistic analyses demonstrated that miR-23b-3p directly targeted TLR4 to suppress its expression. In vivo overexpression of miR-23b-3p ameliorated IgAV manifestations, as evidenced by reduced TLR4 expression on DCs, diminished Tfh cell differentiation, and decreased serum levels of IgA, interleukin (IL)-6, and IL-12. Notably, TLR4 silencing reversed miR-23b-3p inhibitor-induced DC hyperactivation and aberrant Tfh cell differentiation. miR-23b-3p regulates DC maturation and function and subsequent Tfh differentiation in a TLR4-dependent manner. miR-23b-3p deficiency aggravates IgAV by promoting pathogenic DC-Tfh axis activation, whereas restoration of miR-23b-3p expression attenuates immune dysregulation, suggesting a potential therapeutic strategy for IgAV.
Publicações recentes
Colchicine for Skin Involvement in Immunoglobulin A Vasculitis: A Single-Center Case Series and Review of the Literature.
Predictors of the late recurrences of immunoglobulin A vasculitis due to clinical and laboratory features in children.
Gastrointestinal Involvement in Adult IgA Vasculitis: A Comprehensive Review.
miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.
Serum SCUBE1 and SCUBE2 Levels in Children with Immunoglobulin A Vasculitis: An Exploratory Study.
📚 EuropePMC215 artigos no totalmostrando 199
miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.
Rheumatology (Oxford, England)Serum SCUBE1 and SCUBE2 Levels in Children with Immunoglobulin A Vasculitis: An Exploratory Study.
Rheumatology and therapyDemographic, Clinical, and Laboratory Characteristics of Pediatric IgA Vasculitis: A Retrospective Five-Year Single-Center Experience.
Journal of clinical medicineMalignant renovascular hypertension consequent to IgA vasculitis in a young male patient: a case report.
Journal of medical case reportsRenal Shear Wave Elastography for Differentiating Vasculitic and Non-Vasculitic Acute Kidney Injury.
Journal of clinical medicineFirst case of IgA vasculitis atypically presenting as recurrent gastroenteritis from Nepal: a case report and review of the literature.
Annals of medicine and surgery (2012)[More than just purpura-Immunoglobulin A vasculitis in adulthood].
Innere Medizin (Heidelberg, Germany)Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.
Current gastroenterology reportsRecurrent diffuse alveolar hemorrhage in Immunoglobulin A vasculitis.
Respiratory medicine case reportsPainful subcutaneous edema is associated with early age at disease onset in Immunoglobulin A vasculitis patients: A multicenter study.
Clinics (Sao Paulo, Brazil)Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.
JAMA dermatologySystemic and dermatological findings of immunoglobulin A vasculitis in a black child: A case report.
World journal of clinical casesIgA Vasculitis With Nephritis Following Controlled Ovarian Stimulation and Oocyte Donation.
CureusSuspected Alcohol-Induced Immunoglobulin A Vasculitis: A Case Series and Review of the Literature.
Case reports in dermatologyImmunoglobulin A Vasculitis Associated Terminal Ileitis Mimicking Inflammatory Bowel Disease: Diagnostic Challenge and Therapeutic Role of Steroids - A Case Report.
Case reports in dermatologyRole of red cell distribution width, tumor necrosis factor-alpha, and interleukin-6 in immunoglobulin a vasculitis nephritis among Tibetan children in high-altitude areas.
BMC pediatricsUstekinumab-induced Henoch-Schönlein purpura in Crohn's disease: a case report and literature review.
Intestinal researchThe role of NFKB1 and NFKBIA in immunoglobulin A vasculitis.
Frontiers in immunologyCase Report: Severe gastrointestinal complications in adult IgA vasculitis: a fatal case of acute esophageal necrosis.
Frontiers in immunologyAnalysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.
Clinical pediatricsImmunoglobulin A vasculitis with aneurysmal subarachnoid hemorrhage in an adult.
JAAD case reportsPathophysiology of glomerulonephritis in autoimmune diseases.
Current opinion in rheumatologyRecurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.
Clinical and experimental pediatricsEfficacy and safety of telitacicept in children with IgA vasculitis and IgA vasculitis nephritis: a single-center retrospective study.
Pediatric rheumatology online journalSome novel causes and clinical characteristics of reversible splenial lesion syndrome- found in children.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyRisk factors for recurrence or relapse after a first episode of adult IgA vasculitis: A multicenter retrospective study.
Journal of the American Academy of DermatologyEfficacy and Safety of Telitacicept in Adult IgA Vasculitis Nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationSerum elafin levels in patients with IgA vasculitis: a prospective case-control study.
Pediatric rheumatology online journalBiomarker research for Henoch-Schönlein purpura nephritis based on "omics" techniques.
Frontiers in medicineGuidelines for the diagnosis and management of childhood immunoglobulin A vasculitis.
World journal of pediatrics : WJPGastrointestinal bleeding as an early presentation of the pediatric granulomatosis with polyangiitis: A rare report.
SAGE open medical case reportsKDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV).
Kidney internationalExecutive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Immunoglobulin A Nephropathy (IgAN) and Immunoglobulin A Vasculitis (IgAV).
Kidney internationalAtypical presentation of immunoglobulin A vasculitis mimicking acute appendicitis in a pediatric patient: a case report.
Future science OA[The Value of Thrombus Biomarkers for Assessing the Progression of Immunoglobulin A Vasculitis in Children].
Zhongguo shi yan xue ye xue za zhiEvaluation of rheumatic causes underlying childhood-onset arthritis.
Turkish journal of medical sciencesRelief of Suspected IgA Vasculitis-Associated Enterocolitis Manifested as Severe Diarrhea and Hypoalbuminemia Treated With Glucocorticoid Therapy and Administration of Fibrogammin® (Purified Coagulation Factor XIII Concentrate): A Case Report.
CureusVasculitis as an indicator of disease severity in familial Mediterranean fever.
Frontiers in immunologyImmunoglobulin A Vasculitis Following COVID-19 Infection in an Adolescent Girl.
Oman medical journalRisk factors associated with renal injury in patients initially diagnosed with IgA vasculitis.
Frontiers in pediatricsEpidemiology, clinical features and outcomes of patients with kidney biopsy proven IgA vasculitis in Auckland and Northland, Aotearoa, New Zealand presenting between 2003-2020.
BMC nephrologyExploring the Anti-Inflammatory and Anti-NET Properties of Zidian Zhenxiao Granule in IgA Vasculitis: A Network Pharmacology and Proteomic Study.
Journal of inflammation researchSerum IgE and IgA Levels in Pediatric Henoch-Schönlein Purpura: Clinical Characteristics and Immunological Correlations in the Context of Infectious Diseases-A Five-Year Retrospective Analysis.
International journal of molecular sciencesPediatric Immunoglobulin A Vasculitis: Impact of Mediterranean Fever Gene Variants on Clinical Course and Inflammatory Markers.
Turkish archives of pediatricsComprehensive analysis of the clinical and pathological features and prognoses of children with immunoglobulin A vasculitis nephritis with immunoglobulin M deposits in glomeruli.
Kidney research and clinical practicePatients With IgA Vasculitis and Kawasaki Disease Show Dysregulated Interferon Signature.
International journal of rheumatic diseasesThe Importance of Early Steroid Use in IgA Vasculitis Complicated by Disseminated Intravascular Coagulation in an Adult.
CureusMycophenolate Mofetil as a Therapeutic Option in Refractory Immunoglobulin A Vasculitis: A Report of Two Atypical Cases.
CureusSkin Deep: A Narrative Case Series and Review of Cutaneous Vasculitis and Possible Doppelgängers.
The American journal of medicineImmunoglobulin A vasculitis and pustular psoriasis precipitated by Tawon Liar: a case report.
Journal of medical case reportsA case and literature review of axial spondyloarthritis and immunoglobulin A vasculitis: Rare association or under-recognized?
SAGE open medical case reportsAdult-Onset Immunoglobulin A Vasculitis (IgAV) Presenting in a Middle-Aged Indian Male Patient.
CureusNETs in the spotlight: exploring NETosis markers for tracking disease activity in IgA vasculitis.
Rheumatology (Oxford, England)Laboratory Findings and Clinical Features in IgA Vasculitis: Identifying Predictors of Kidney Involvement and Disease Relapse in Pediatric Patients.
Journal of clinical medicineImmunoglobulin a vasculitis with central nervous system involvement: analysis of 10 cases.
Clinical and experimental medicineTph cells are expanded in IgA vasculitis nephritis.
Molecular immunologyA case-based review of IgA vasculitis complicated with gastrointestinal infections: insights from a norovirus-associated case in an adolescent.
Rheumatology internationalEfficacy and Safety of Telitacicept as an Add-On Therapy for Refractory Immunoglobulin A Nephropathy or Immunoglobulin A Vasculitis Nephropathy in Children.
Kidney international reportsTelitacicept as a BAFF/APRIL dual inhibitor: efficacy and safety in reducing proteinuria for refractory childhood IgA vasculitis nephritis.
Pediatric nephrology (Berlin, Germany)Assessment of renal resistive index measurement in children with immunoglobulin A vasculitis.
ReumatologiaDifferential gut microbiota and inflammatory cytokines contribute to IgA vasculitis.
Clinical and experimental rheumatologyHow familial Mediterranean fever affects the characteristics of immunoglobulin a vasculitis in pediatric patients at the time of diagnosis?
European journal of pediatricsA case report of Henoch-Schönlein purpura in the elderly complicated by multisystem involvement.
MedicineUnilateral Cheek Edema in a Child with Immunoglobulin A Vasculitis.
Indian pediatricsPatterned eruption following fishnet stocking use.
JAAD case reportsAn Atypical Presentation of Henoch-Schönlein Purpura With Features of Acute Hemorrhagic Edema of Infancy and Koebnerization: A Case Report.
CureusRelationship between IgA vasculitis and prothrombotic risk factors: A prospective, case-control study.
Archives of rheumatologyUstekinumab-Induced Vasculitis in a Patient With Crohn's Disease.
ACG case reports journalSevere colitis in a patient with immunoglobulin A vasculitis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverTonsillectomy in Immunoglobulin A vasculitis with nephritis: case series.
CEN case reportsThe extent of intestinal involvement is closely related to the severity of IgAV: a risk stratification study based on CT.
Annals of medicineClinical features of abdominal immunoglobulin A vasculitis in adults: a single-center retrospective study.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract[Clinicopathological significance and prognostic value of serum 25-hydroxyvitamin D3 level in children with IgA vasculitis nephritis].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsFactors associated with renal involvement in adult immunoglobulin a vasculitis: what is it?
Postgraduate medicine[Clinical and pathological features of children with immunoglobulin A vasculitis with nephritis accompanied by different proportions of crescent formation].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsEpidemiology of systemic vasculitis.
Current opinion in rheumatologyImmunoglobulin A Vasculitis Nephritis in an Adult.
CureusExploring the predictive factors in the gastrointestinal involvement of patients with immunoglobulin A vasculitis.
The Turkish journal of pediatricsCharacteristics of cutaneous manifestations in immunoglobulin a vasculitis and their relationships with system involvement and treatment needs.
European journal of pediatricsCan the affected intestinal segment visualized on abdominal ultrasound predict gastrointestinal tract bleeding in immunoglobulin A vasculitis?
Modern rheumatologyGastrointestinal manifestations and pathogenesis in childhood immunoglobulin A vasculitis.
Frontiers in pediatricsDelayed diagnosis of angioimmunoblast T-cell lymphoma presenting with immunoglobulin a vasculitis.
Renal failureRisk Factors for Renal Involvement in Childhood Henoch-Schonlein Purpura (IgA Vasculitis).
Journal of the College of Physicians and Surgeons--Pakistan : JCPSPImmunoglobulin A vasculitis with Koebner phenomenon and renal involvement induced by antitumor necrosis factor α therapy in the treatment of rheumatoid arthritis.
Polish archives of internal medicineAssociation of Childhood IgA Vasculitis With Allergic Rhinitis and Chronic Rhinosinusitis.
Kidney international reportsBlood soluble CD89-IgA complex may be a potential biomarker for predicting multi-organ involvement, especially renal involvement in children with immunoglobulin A vasculitis.
International immunopharmacologyAmelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17 cells.
Journal of autoimmunityCase report: Nephritic/nephrotic syndrome in a child with immunoglobulin A vasculitis.
International journal of rheumatic diseasesExplore the Value of Multi-Parameter MRI in Non-Invasive Assessment of Prognostic Risk and Oxford Classification in Children with IgAN or IgAVN.
Bioengineering (Basel, Switzerland)Immunoglobulin A vasculitis with periorbital edema and severe renal involvement: A case report.
Pediatric dermatologyComparison of different doses of Tripterygium glycosides treating in IgA vasculitis nephritis: A Bayesian network meta-analysis.
HeliyonFasciitis as a Complication of IgA Vasculitis.
CureusAn Unusual Case of Abdominal Pain in a Geriatric Man.
The Journal of emergency medicineA Case Series of Unusual IgA Vasculitis.
HCA healthcare journal of medicineAn Unusual Presentation of Propylthiouracil-Induced Immunoglobulin A Vasculitis With Positive Anti-proteinase-3 and Anti-myeloperoxidase Antibodies.
CureusClinical characteristics and risk factors for kidney involvement in children with immunoglobulin A vasculitis.
Pediatrics international : official journal of the Japan Pediatric SocietyImmunoglobulin A vasculitis: The clinical features and pathophysiology.
The Kaohsiung journal of medical sciencesReporting the clinical spectrum of children with IgAV in a retrospective 24-year cohort: Influences of age and sex on clinical presentation.
Turkish journal of medical sciencesImmunoglobulin A Vasculitis After Initiation of Treatment for Tuberculous Pleurisy: A Case Report and Literature Review.
CureusHenoch-Schönlein purpura following mRNA COVID-19 vaccination: a case report.
Clinical and experimental vaccine researchThe efficacy and safety of tacrolimus in treating refractory IgA vasculitis nephritis: a single-center retrospective study on 16 cases.
Clinical kidney journalAnnular Leukocytoclastic Vasculitis: A New Feature of IgA Vasculitis.
European journal of case reports in internal medicineA Rare Case of Immunoglobulin A Vasculitis in an Adult Male.
CureusDeregulation in adult IgA vasculitis skin as the basis for the discovery of novel serum biomarkers.
Arthritis research & therapySingle-cell RNA sequencing of pediatric renal tissues revealed the potential relationship between immunoglobulin A nephropathy and immunoglobulin A vasculitis with nephritis.
Clinical and translational medicineExtracellular CIRP co-stimulated T cells through IL6R/STAT3 in pediatric IgA vasculitis.
Biochimica et biophysica acta. Molecular basis of diseaseAng-1, Ang-2, and Tie2 are diagnostic biomarkers for Henoch-Schönlein purpura and pediatric-onset systemic lupus erythematous.
Open life sciencesSevere immunoglobulin A vasculitis with refractory gastrointestinal involvement in an adult patient successfully treated with plasma exchange.
Scandinavian journal of rheumatology[Urinary protein and renal pathological features in children with immunoglobulin A vasculitis with nephritis and hypercoagulability].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsTaxonomic and functional shifts of gut microbiome in immunoglobulin A vasculitis children and their mothers.
Frontiers in pediatricsEpidemiology and clinical characteristics of biopsy-confirmed adult-onset IgA vasculitis in southern Sweden.
RMD openASSOCIATION BETWEEN HIGH MOBILITY GROUP BOX 1 PROTEIN GENE (rs41369348) POLYMORPHISM AND IMMUNOGLOBULIN A VASCULITIS IN CHILDREN.
Acta clinica CroaticaClinical characteristics and risk factors of cardiac involvement in pediatric immunoglobulin A vasculitis: A 7-year retrospective study from a single tertiary medical center.
European journal of pediatricsWorldwide Distribution and Extracutaneous Manifestations of Henoch-Schönlein Purpura in Adults: Narrative Review.
JMIR dermatologyImmunoglobulin A Vasculitis With Intussusception in Children.
The American surgeon[Immunoglobulin A vasculitis].
Innere Medizin (Heidelberg, Germany)Successful rituximab therapy in adult-onset IgA vasculitis with diffuse alveolar hemorrhage and renal failure: a case report.
AME case reportsOutcome of immunosuppression in children with IgA vasculitis-related nephritis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationPossible Threats of IgA Vasculitis in Children: One Center Experience.
Acta medica LituanicaDoes age at disease onset affect the clinical presentation and outcome in children with immunoglobulin A vasculitis?
Archives of rheumatologyRituximab as possible therapy in TNF inhibitor-induced IgA vasculitis with severe renal involvement.
BMC nephrology[Research advances in the etiology and pathogenesis of immunoglobulin A vasculitis].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsAnalysis of IL-1β, TGF-β, IL-5, ACE, PTPN22 gene polymorphisms, and gene expression levels in Turkish children with IgA vasculitis.
Molecular biology reportsImmunoglobulin A vasculitis involving the duodenum and jejunum.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver[Association between vaccination and the risk of immunoglobulin A vasculitis in children].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsRenal Medullary Angiitis Associated with Cutaneous Leukocytoclastic Vasculitis.
Internal medicine (Tokyo, Japan)Immunoglobulin-A vasculitis manifesting as edema in the scalp, face, and sternocleidomastoid muscle.
International journal of rheumatic diseasesImmunoglobulin A Vasculitis as a Sign of Recurrence of Lingual Cancer.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseasesImmunoglobulin A Vasculitis Following ChadOx1 nCoV-19/AZD1222 (AstraZeneca COVID-19 Vaccine) Vaccination.
Annals of dermatologyImmunoglobulin A vasculitis nephritis: Current understanding of pathogenesis and treatment.
World journal of nephrologyMucosal Immune Defence Gene Polymorphisms as Relevant Players in the Pathogenesis of IgA Vasculitis?
International journal of molecular sciencesAtypical Immunoglobulin A Vasculitis in a Pediatric Patient With Ulcerative Colitis.
ACG case reports journalAssociation between Factor XIII Activity and Clinical Course in Pediatric Patients with Immunoglobulin A Vasculitis.
The Kobe journal of medical sciencesRenal pathology in adult and paediatric population of Japan: review of the Japan renal biopsy registry database from 2007 to 2017.
Journal of nephrologyPregnancy outcome in patients with a medical history of immunoglobulin A vasculitis: a case-control study.
Scandinavian journal of rheumatologyAZGP1 as a potential biomarker of IgA vasculitis with nephritis in a children‑based urinary proteomics study by diaPASEF.
Molecular medicine reportsHenoch-Schönlein purpura with antecedent allergic diseases in a 4-year-old child: a case report.
Annals of medicine and surgery (2012)Immunoglobulin A Vasculitis: Contemplating Treatment for Gastrointestinal Involvement.
Cureus[Immunoglobulin A vasculitis (IgAV)].
Zeitschrift fur RheumatologieBowman's capsule rupture and the Oxford MEST-C score in adult patients with Immunoglobulin a vasculitis nephritis: a single center experience.
Annals of medicineEffect of Nonimmune Factors on Renal Prognosis in Adult IgA Vasculitis With Nephritis: A Long-Term Retrospective Cohort Study.
The Journal of rheumatologyExtensive Palpable Purpura Preceding Renal Dysfunction in Immunoglobulin A Vasculitis Due to Coronavirus-19 Infection.
The American journal of medicineCyclosporin A in combination with corticosteroids as a treatment for immunoglobulin A vasculitis nephritis in children.
Minerva pediatricsImmunoglobulin a vasculitis with testicular/epididymal involvement in children: A retrospective study of a ten-year period.
Frontiers in pediatricsPathophysiology and clinical manifestations of immune complex vasculitides.
Frontiers in medicineIgA Vasculitis in Japanese Patients Harboring MEFV Mutations: A Case Report and Review of the Literature.
CureusAutoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review.
Journal of autoimmunityAdult-Onset Immunoglobulin A Vasculitis Following Hemodialysis Treatment: An Unusual Presentation.
CureusAssociation of the Monocyte-to-High-Density Lipoprotein Cholesterol Ratio with Gastrointestinal Involvement of Immunoglobulin a Vasculitis.
Clinical, cosmetic and investigational dermatologyIntussusception as a rare manifestation of immunoglobulin A vasculitis: Risk factors and treatment.
Journal of paediatrics and child healthImmunoglobulin A vasculitis presenting as bilateral upper eyelid erythema: A case report and review of literature.
Pediatric dermatologySuccessful treatment of rituximab in a steroid-dependent immunoglobulin A vasculitis patient with gastrointestinal involvement: a case report.
Scandinavian journal of rheumatologyLandscape of intestinal microbiota in patients with IgA nephropathy, IgA vasculitis and Kawasaki disease.
Frontiers in cellular and infection microbiologyAdult invasive meningococcal disease caused by Neisseria meningitidis classified as serogroup B and sequence type 15947.
The Journal of dermatologyGastrointestinal Bleeding Induced by Immunoglobulin A Vasculitis on Post-Mild COVID-19 Patients.
CureusVenous sinus thrombosis in a case of immunoglobulin A vasculitis and a systemic review of literature.
International journal of rheumatic diseasesThe spectrum and changes of biopsy-proven kidney diseases in Chinese children.
Journal of nephrologyIntravenous immunoglobulin therapy in immunoglobulin A vasculitis with gastrointestinal tract involvement.
Clinical and experimental medicineEffects of diurnal variation of bile acids by meal on cyclosporine A absorption.
Pediatrics international : official journal of the Japan Pediatric SocietyPreadolescent-versus adolescent-onset immunoglobulin A vasculitis: The impact of age on prognosis.
Pediatrics international : official journal of the Japan Pediatric SocietyAssociation of human leukocyte antigen with IgA vasculitis with nephritis in Japanese children.
Pediatrics international : official journal of the Japan Pediatric Society50 Years Ago in TheJournalofPediatrics: Are We Any Better at Understanding the Prognosis of Immunoglobulin A Vasculitis Nephritis?
The Journal of pediatricsImmunoglobulin A vasculitis in a child: Secondary to COVID-19 or cystic fibrosis?
Pediatric pulmonologyCOVID-19 associated immunoglobulin A vasculitis in an adult.
JAAD case reportsIgA vasculitis update: Epidemiology, pathogenesis, and biomarkers.
Frontiers in immunologySerum pepsinogen cut-off values in Helicobacter pylori-infected children.
Pediatrics international : official journal of the Japan Pediatric SocietyRefractory Immunoglobulin A (IgA) Vasculitis in an Elderly Patient: A Case Report.
CureusImmunoglobulin A Vasculitis Following COVID-19: A French Multicenter Case Series.
The Journal of rheumatologyIgA Vasculitis: Influence of CD40, BLK and BANK1 Gene Polymorphisms.
Journal of clinical medicineUrinary complement proteins are increased in children with IgA vasculitis (Henoch-Schönlein purpura) nephritis.
Pediatric nephrology (Berlin, Germany)Acute pancreatitis associated with immunoglobulin A vasculitis: report of fifteen cases.
Clinical rheumatologyImmunoglobulin A vasculitis induced by atypical pneumonia infection with Chlamydophila pneumonia.
IDCasesImmunoglobulin A Vasculitis Associated With COVID-19 Infection Successfully Treated With Corticosteroid Regimen Without Relapse.
CureusTubulointerstitial B-cell infiltration and tertiary lymphoid tissue in adult-onset immunoglobulin A vasculitis with nephritis.
International urology and nephrologyCoronavirus disease 2019, vaccination against coronavirus and immunoglobulin A-mediated diseases: systematic literature review.
Journal of autoimmunityClinical features of paediatric immunoglobulin A vasculitis patients with scrotal involvement.
Modern rheumatologyA Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient.
CureusRisk assessment and prediction model of renal damage in childhood immunoglobulin A vasculitis.
Frontiers in pediatricsDapsone for Refractory Gastrointestinal Symptoms in Children With Immunoglobulin A Vasculitis.
PediatricsIndividualized medication based on pharmacogenomics and treatment progress in children with IgAV nephritis.
Frontiers in pharmacologyRelevance of Intestinal Microbiota in Immunoglobulin A Vasculitis With Abdominal Involvement.
Frontiers in pediatricsSteroid-resistant peripheral neuropathy in a child: a rare finding in immunoglobulin a vasculitis.
The Turkish journal of pediatricsAssociation of Pediatric Vasculitis Activity Score with immunoglobulin A vasculitis with nephritis.
Pediatric nephrology (Berlin, Germany)Mean platelet volume may not play a role in the differential diagnosis of immunoglobulin A vasculitis and appendicitis in children.
Updates in surgeryFindings on the Relationship Between Intestinal Microbiome and Vasculitis.
Frontiers in cellular and infection microbiologyAn Emerging Role for Neutrophil Extracellular Traps in IgA Vasculitis: A Mini-Review.
Frontiers in immunologyAdjunctive treatment with infliximab in pediatric immunoglobulin A (IgA) vasculitis: A case report.
Pediatric dermatologyBlood routine examination: a simple way for differential diagnosis of immunoglobulin A vasculitis with abdominal involvement and appendicitis in children.
Updates in surgeryCOVID-19 and New Onset IgA Vasculitis: A Systematic Review of Case Reports.
Journal of emergency nursingRetroperitoneal fibrosis requiring prompt nephrostomy in a case with immunoglobulin A vasculitis.
Scandinavian journal of rheumatologyLumbar swelling and migrating edema in 3- and 4-year-old boys.
SAGE open medical case reportsUrinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis.
Children (Basel, Switzerland)High levels of platelet-to-lymphocyte ratio may predict reduced risk of end stage of renal disease in Chinese patients with MPO-ANCA associated vasculitis.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciencesAdult Onset Immunoglobulin A (IgA) Vasculitis Secondary to Group A Streptococcus Infection.
CureusAdult-Onset Immunoglobulin A Vasculitis With Renal Involvement.
CureusSertraline-Associated Immunoglobulin A Vasculitis.
American journal of therapeuticsGenome-wide association study of 7661 Chinese Han individuals and fine-mapping major histocompatibility complex identifies HLA-DRB1 as associated with IgA vasculitis.
Journal of clinical laboratory analysisAn Immunoglobulin A Vasculitis Case Without Skin Symptoms Complicated With Severe Abdominal Symptoms.
Journal of medical casesBlood transthyretin for predicting immunoglobulin A vasculitis nephritis outcome in children.
International immunopharmacologyAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Risk Factors and Outcomes of Immunoglobulin A Vasculitis in Patients with Inflammatory Bowel Disease and vice versa: A Systematic Review of the current literature.
- Zanubrutinib for Immunoglobulin A Vasculitis With Monoclonal Gammopathy.
- Analysis of Clinical Features and High-Risk Factors of Gastrointestinal Involvement in Children With IgA Vasculitis.
- Recurrent immunoglobulin A vasculitis in children and adolescents: prevalence and associated risk factors.
- miR-23b-3p deficiency exacerbates immune dysregulation in immunoglobulin A vasculitis by enhancing TLR4-mediated dendritic cell activation.
- Colchicine for Skin Involvement in Immunoglobulin A Vasculitis: A Single-Center Case Series and Review of the Literature.
- Predictors of the late recurrences of immunoglobulin A vasculitis due to clinical and laboratory features in children.
- Gastrointestinal Involvement in Adult IgA Vasculitis: A Comprehensive Review.
- Serum SCUBE1 and SCUBE2 Levels in Children with Immunoglobulin A Vasculitis: An Exploratory Study.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:761(Orphanet)
- MONDO:0019167(MONDO)
- GARD:8204(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q1035319(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
