Severe ethylene glycol toxicity leading to persistent kidney disease.

A novel therapy for pyridoxine-dependent epilepsy due to biallelic pathogenic variants in ALDH7A1: secondary mitochondrial energy deficiency and improvements of neurodevelopmental outcomes on triheptanoin treatment.

Antinuclear antibody (ANA) level and blood-profile in Oral lichen planus patients: A cross-sectional study.

Gyrate atrophy of the choroid and retina: a tertiary center experience.

Clinical Approaches and Emerging Therapeutic Horizons in Primary Hyperoxaluria.

The neuropathological mechanisms underlying the inborn errors of lysine metabolism.

Assessment of the nutritional status of Syrian refugee women in the lactation period.

Gut microbiota response to Enterocytozoon bieneusi infection in wild rodents: enhanced vitamin B and K2 biosynthesis pathways.

Branched-chain amino acid transferase 2 (BCAT2) deficiency: A case series and systematic review.

B Vitamin Deficiencies and Associated Neuropathies.

Liver Transplantation in PNPO Deficiency: Management Challenges and Biological Lessons.

Current neonatal seizure classification and approach to the newborn with seizure.

Hippophae rhamnoides: Way to Ameliorate Depressive Augury by Cyanocobalamin.

Jinlida ameliorates diabetic kidney disease via gut microbiota-dependent production of pyridoxamine targeting renal AGEs/RAGE and TGF-β pathways.

β-caryophyllene mitigates metabolic dysfunction in the testes of gerbils perinatally exposed to BPA.

Structure-activity relationship of S-adenosylmethionine analogs as pharmacological chaperones for cystathionine beta-synthase-deficient homocystinuria.

Acute vision loss associated with vincristine therapy in T cell lymphoma.

Hepatocellular Carcinoma: A Critical Complication in Patients Treated with Pyridoxal Phosphate.

Vitamin B6 form produced by Lactobacillus induces metabolic disorder and suppresses multi-pathogenic bacteria.

Pyridoxine-dependent early onset seizures associated with rare gene mutations: A case series.

Untargeted Metabolomics for Diagnosis, Monitoring, and Understanding the Pathophysiology of Inherited Metabolic Disorders.

Chromothriptic Translocation t(1;18): A Paradigm of Genomic Complexity in a Child with Normal Intellectual Development and Pyridoxine-Dependent Epilepsy.

Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review).

Cardiac Manifestations of Nutritional Deficiencies.

Lysine α-ketoglutarate reductase as a therapeutic target for saccharopine pathway related diseases.

Will a "multivitamin" a day keep the "MASLD doctor" away?

Targeting AASS alleviates neurotoxicity and improves mitochondrial function in astrocyte models for pyridoxine-dependent epilepsy.

Is Vitamin B6 a Precision Therapy for Neonatal Seizures?

Lactic acidosis, rhabdomyolysis, and hyperammonemia: Atypical presentation in a new patient with PDE-ALDH7A1 defect.

Metabolic changes in root exudates of plants with different disease severity affect plant resistance by regulating the rhizosphere microbiome.

Vitamin B6 (Pyridoxal 5' Phosphate) antagonises carotid body P2X3 receptors in hypertension.

A Treatable Cause of Seizures and Hyperphosphatasia: Patients with PGAP2 and PGAP3 Mutations.

Bridging the gap: pyridoxine-dependent epilepsy (PDE-ALDH7A1) diagnosis and management in a low-resource setting.

Targeted Microbial Shifts and Metabolite Profiles Were Associated with Clinical Response to an Anti-Inflammatory Diet in Osteoarthritis.

Neonatal Refractory Seizures and Hyperammonemia in a Neonate With ALDH7A1 Deficiency.

Exploring neuropsychiatric manifestations of vitamin B complex deficiencies.

Video-EEG as a precision medicine tool in vitamin-dependent epilepsy: A clinical experience.

Transcriptomics assisted by metabolomics analysis provides insights into regulation mechanisms during carcinogenic process in a hydrodynamically transfected liver cancer model.

Advancing Neonatal Screening for Pyridoxine-Dependent Epilepsy-ALDH7A1 Through Combined Analysis of 2-OPP, 6-Oxo-Pipecolate and Pipecolate in a Butylated FIA-MS/MS Workflow.

Association between vitamin B6 status and liver fibrosis: evidence from NHANES 2005-2010.

Combination Therapy with Pyridoxine and Arginine Supplementations along with a Lysine-Restricted Diet in Individuals with Pyridoxine-Dependent Epilepsy: A Comprehensive Systematic Review.

Novel Homozygous MTHFR Variant Causing Homocystinuria: Subtle Phenotypic Clues in Carriers.

Effectiveness of Pyridoxal-5'-Phosphate in PNPO Deficiency: A Systematic Review.

Two new cases of KYNU deficiency: Further delineation of the phenotypic and biochemical spectrum and exploration of treatment options.

Synthetic Metabolites Derived From Host-Exudates Modulate the Bacterial Wilt Occurrence.

Use of lysine reduction therapies in patients with pyridoxine dependent epilepsy due to Antiquitin deficiency - A cohort study.

Hypocupraemia-related drug-refractory seizures in Wilson disease.

Lumasiran at birth changes the trajectory of primary hyperoxaluria type 1: same disease, different outcomes in two affected siblings.

Comprehensive Review of L-Lysine: Chemistry, Occurrence, and Physiological Roles.

Neglected micronutrients-considering a broader set of vitamins and minerals in public health nutrition programs worldwide: a narrative review.

Vitamin B6 challenge as a tool for detecting ALPL mutations and diagnosing hypophosphatasia.

Plasma Glycolate Levels Contribute to Drive the Decision of Isolated Kidney Transplantation in Dialyzed Patients with End-Stage Kidney Disease due to Primary Hyperoxaluria Type 1 Treated with Lumasiran: A Case Report.

Structure Elucidation for MALDI Mass Spectrometry Imaging Using Infrared Ion Spectroscopy.

Impact of azithromycin on specific biochemical markers and sebum composition in acne vulgaris patients.

The Clinical and Biochemical Impact of the Multivitamin Shortage on Neonatal Patients.

Lyophilised reservoirs in combination with hydrogel-forming microarray patches for transdermal delivery of isoniazid and pyridoxine hydrochloride.

Targeting Lysine α-Ketoglutarate Reductase to Treat Pyridoxine-Dependent Epilepsy.

The disease-linked R336C mutation in cystathionine β-synthase disrupts communication with the PLP cofactor, yet maintains the enzyme's overall structural integrity.

A study of Iraqi patients with homocysteine remethylation disorders in a tertiary pediatric centre.

Branched-chain amino acid transferase type 2 (BCAT2) deficiency: Report of an eighth case and literature review.

Can pyridoxine function as an anti-pyroptosis agent? A narrative review.

Broad Vitamin B6-Related Metabolic Disturbances in a Zebrafish Model of Hypophosphatasia (TNSALP-Deficiency).

Pyridoxine exerts antioxidant effects on kidney injury manifestations in high-fat diet-induced obese rats.

The Role of Vitamin B Complex in Periodontal Disease: A Systematic Review Examining Supplementation Outcomes, Age Differences in Children and Adults, and Aesthetic Changes.

The role of genetic testing in accurate diagnosis of X-linked sideroblastic anemia: novel ALAS2 mutations and the impact of X-chromosome inactivation.

Effectiveness and Safety of High-Dose Oral Phenobarbital in Children With Recurrent and Treatment-Refractory Seizures.

Vitamin B6 deficiency produces metabolic alterations in Drosophila.

Cystathionine β-Synthase Deficiency in the E-HOD Registry-Part II: Dietary and Pharmacological Treatment.

Recent Advances on the Role of B Vitamins in Cancer Prevention and Progression.

Protective effects of pyridoxine, amlodipine, and their combination in a vasopressin-induced angina model in rats.

Sideroblastic anemia in children: challenges in diagnosis and management in three cases.

Dysregulation of astrocyte-derived matrix gla protein impairs dendritic spine development in pyridoxine-dependent epilepsy.

Inclusion of pyridoxine dependent epilepsy in expanded newborn screening programs by tandem mass spectrometry: set up of first and second tier tests.

Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria.

Plasma metabolome reveals altered oxidative stress, inflammation, and amino acid metabolism in dogs with idiopathic epilepsy.

Investigating the Impact of Selected B Vitamins (B1, B2, B6, and B12) on Acute Colitis Induced Experimentally in Rats.

Feasibility of newborn screening for pyridoxine-dependent epilepsy.

Determination of new biomarkers for diagnosis of pyridoxine dependent epilepsy in human plasma and urine by liquid chromatography-mass spectrometry.

Pyridoxine supplementation before puberty ameliorates MAM-induced cognitive and sensorimotor gating impairments.

Role of Vitamin B in Healthy Ageing and Disease.

Restricting lysine normalizes toxic catabolites associated with ALDH7A1 deficiency in cells and mice.

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Parkinson's Disease: Unravelling the Medicinal Perspectives and Recent Developments of Heterocyclic Monoamine Oxidase-B Inhibitors.

Pyridoxine-dependent epilepsy caused by an ALDH7A1 mutation in an infant girl: the first case report in Syria.

Sprayable inflammasome-inhibiting lipid nanorods in a polymeric scaffold for psoriasis therapy.

[Phenotype of infantile epileptic spasm syndrome in pyridoxin-dependent epilepsy].

Case report: Early (molecular) diagnosis is the clue: report on ALDH7A1 deficiency in newborns.

Fresh bamboo juice regulates the diversity of intestinal microflora in mice by promoting the function of ILC2 cells to mediate intestinal protection.

Management of Alzheimer's disease and related neurotoxic pathologies: Role of thiamine, pyridoxine and cobalamin.

Mild/moderate phenotypes in AADC deficiency: Focus on the aromatic amino acid decarboxylase protein.

Characteristics of isoniazid-induced psychosis: a systematic review of case reports and case series.

Mutation Characteristics of Primary Hyperoxaluria in the Chinese Population and Current International Diagnosis and Treatment Status.

Ocoxin Oral Solution Triggers DNA Damage and Cell Death in Ovarian Cancer.

Challenges in Hypophosphatasia: Suspicion, Diagnosis, Genetics, Management, and Follow-Up.

Assessment of urinary 6-oxo-pipecolic acid as a biomarker for ALDH7A1 deficiency.

Circulating B vitamins metabolites in depressive disorders - connections with the microbiota-gut-brain axis.

Effects of different energy levels in low-protein diet on liver lipid metabolism in the late-phase laying hens through the gut-liver axis.

Generation of hiPSC lines from four pyridoxine-dependent epilepsy (PDE) patients carrying the variant c.1279G>C in ALDH7A1 in homozygosis.

Delivery of exogenous miR-19b by Wharton's Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism.

Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine.

[B vitamins and diseases of the peripheral nervous system].

Komrower Memorial Lecture 2023. Molecular basis of phenotype expression in homocystinuria: Where are we 30 years later?

7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase.

Identifying Metabolic Diseases That Precipitate Neonatal Seizures.

Dietary management for pyridoxine-dependent epilepsy due to α-aminoadipic semialdehyde dehydrogenase deficiency, a follow-on from the international consortium guidelines.

Seizures due to pyridoxine deficiency in Parkinson's disease.

Association of Increased Homocysteine Levels with Impaired Folate Metabolism and Vitamin B Deficiency in Early-Onset Multiple Sclerosis.

Biochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1.

Blocking proteinase-activated receptor 2 signaling relieves pain, suppresses nerve sprouting, improves tissue repair, and enhances analgesic effect of B vitamins in rats with Achilles tendon injury.

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria.

Pyridoxal 5'-Phosphate Biosynthesis by Pyridox-(am)-ine 5'-Phosphate Oxidase: Species-Specific Features.

Host metabolomic responses in recurrent P. vivax malaria.

Metabolic etiologies in children with infantile epileptic spasm syndrome: Experience at a tertiary pediatric neurology center.

Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study.

A Gadolinium(III) Complex Based on Pyridoxine Molecule with Single-Ion Magnet and Magnetic Resonance Imaging Properties.

Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin B6 metabolism.

Study on the mechanism of vitamin E alleviating non-alcoholic fatty liver function based on non-targeted metabolomics analysis in rats.

Micronutrient Deficiency in Inherited Metabolic Disorders Requiring Diet Regimen: A Brief Critical Review.

Pyridoxine Deficiency and Neurologic Dysfunction: An Unlikely Association.

Prevalence estimate of sphingosine phosphate lyase insufficiency syndrome in worldwide and select populations.

Ramen noodle neuropathy: an atypical case of partial paralysis from malnutrition.

Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia.

Lower levels of the neuroprotective tryptophan metabolite, kynurenic acid, in users of estrogen contraceptives.

Association of B vitamin intake and total homocysteine levels with all-cause and cause-specific mortality in central obesity.

The effectiveness of citrates and pyridoxine in the treatment of kidney stones.

Treatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures.

Pearls & Oy-sters: Delayed Response to Pyridoxine in Pyridoxine-Dependent Epilepsy.

Generation of an induced pluripotent stem cell line carrying biallelic deletions (SCTCi019-B) in ALDH7A1 using CRISPR/Cas9.

Update current understanding of neurometabolic disorders related to lysine metabolism.

Natural history of urine and plasma oxalate in children with primary hyperoxaluria type 1.

Recent advances in neurometabolic diseases: The genetic role in the modern era.

Is withdrawal of nocturnal hyperhydration possible in children with primary hyperoxaluria treated with RNAi?

Physiological Associations between Vitamin B Deficiency and Diabetic Kidney Disease.

A Non-targeted Metabolomics Reveals Therapeutical Effect and Mechanism of Sanmiao Pill on Adjuvant-induced Arthritis Rats.

Relationship Between Vitamins and Diabetes.

Nutritional Support System (NSS) as a New Therapeutic Strategy for Cerebral Palsy.

Pyridoxine-dependent epilepsy: Current perspectives and questions for future research.

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.

Demand for Water-Soluble Vitamins in a Group of Patients with CKD versus Interventions and Supplementation-A Systematic Review.

Untargeted, High-Resolution Metabolomics in Pediatric Eosinophilic Esophagitis.

Biochemical and cellular effects of a novel missense mutation of the AGXT gene associated with Primary Hyperoxaluria Type 1.

Hyperphosphatasia with mental retardation syndrome 3: Cerebrospinal fluid abnormalities and correction with pyridoxine and Folinic acid.

Preventing Vitamin B6-Related Neurotoxicity.

Infantile Spasms without Hypsarrhythmia and Paroxysmal Eye-Head Movements in an Infant with a Pyridoxine-Dependent Epilepsy due to PLPBP/PLPHP Deficiency.

Chemical Modifications of Pyridoxine for Biological Applications: An Overview.

Recent therapeutic approaches to cystathionine beta-synthase-deficient homocystinuria.

Pyridoxine-dependent Epilepsy caused by a Novel homozygous mutation in PLPBP Gene.

Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond.

Validated UPLC-MS/MS method for the analysis of vitamin B6 pyridoxal 5́-phosphate, pyridoxal, pyridoxine, pyridoxamine, and pyridoxic acid in human cerebrospinal fluid.

Metabolomics analysis of antiquitin deficiency in cultured human cells and plasma: Relevance to pyridoxine-dependent epilepsy.

Targeting the Diagnosis in an Adolescent with Epilepsy and Intellectual Disability through Next-Generation Metabolic Screening.

Nutrient patterns and non-alcoholic fatty liver disease in Iranian Adul: A case-control study.

Homocystinuria diagnosis and management: it is not all classical.

Association Between Lysine Reduction Therapies and Cognitive Outcomes in Patients With Pyridoxine-Dependent Epilepsy.

Case report: Fatal outcome of pyridoxine-dependent epilepsy presenting as respiratory distress followed by a circulatory collapse.

CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1.

Refractory Seizures Secondary to Vitamin B6 Deficiency in Parkinson Disease: The Role of Carbidopa-Levodopa.

Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran.

A sensitive UPLC-MS/MS method for simultaneous quantification of one-carbon metabolites & co-factors in human plasma.

A possible ocular biomarker for response to hyperornithinemia in gyrate atrophy: the effect of pyridoxine, lysine, and arginine-restricted diet in a patient with advanced disease.

Effect of vitamin B6 on pain, disease severity, and psychological profile of fibromyalgia patients; a randomized, double-blinded clinical trial.

Pyridoxine-dependent epilepsy (PDE-ALDH7A1) in adulthood: A Dutch pilot study exploring clinical and patient-reported outcomes.

The Microbiota and It's Correlation With Metabolites in the Gut of Mice With Nonalcoholic Fatty Liver Disease.

A vitamin a day keeps the doctor away: The need for high quality pyridoxal-5'-phosphate.

Pyridoxal Kinase of Disease-causing Human Parasites: Structural and Functional Insights to Understand its Role in Drug Discovery.

Comparative Study to Evaluate the Effect of Low-Protein Diet Supplementation with Taurine and N-Acetylcysteine, N-Acetylcysteine and Pyridoxamine Dihydrochloride in Preventing the Progression of Chronic Renal Failure in Patients with Non-Diabetic Kidney Disease.

Primary hyperoxaluria type 1: novel therapies at a glance.

Vitamin B6 Deficiency Anemia Attributed to Levodopa/Carbidopa Intestinal Gel Therapy for Parkinson's Disease: A Diagnostic Pitfall for Myelodysplastic Syndrome with Ring Sideroblasts.

Nutrition interventions in congenital disorders of glycosylation.

Clinical Reasoning: Pediatric Seizures of Unknown Cause.

ESPEN micronutrient guideline.

Clinical, Biochemical, Radiological, and Genetic Profile of Patients with Homocysteine Remethylation Pathway Defect and Spastic Paraplegia.

Status Epilepticus due to Asfotase Alfa Interruption in Perinatal Severe Hypophosphatasia.

Timing of therapy and neurodevelopmental outcomes in 18 families with pyridoxine-dependent epilepsy.

A case for newborn screening for pyridoxine-dependent epilepsy.

Pyridoxine or pyridoxal-5-phosphate treatment for seizures in glycosylphosphatidylinositol deficiency: A cohort study.

Pyridoxine-Dependent Epilepsy and Antiquitin Deficiency Resulting in Neonatal-Onset Refractory Seizures.

Metabolic Therapy of Heart Failure: Is There a Future for B Vitamins?

Hypoventilation and progressive encephalopathy in a neonate with MTHFR deficiency.

Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine.

Identification of three novel pathogenic mutations in cystathionine beta-synthase gene of Pakistani intellectually disabled patients.

Primary Hyperoxaluria Type 1 (PH1) Presenting With End-Stage Kidney Disease and Cutaneous Manifestations in Adulthood: A Case Report.

Transcriptomics integrated with metabolomics reveals the effect of Bisphenol F (BPF) exposure on intestinal inflammation.

Characterization of Novel Pathogenic Variants Causing Pyridox(am)ine 5'-Phosphate Oxidase-Dependent Epilepsy.

B Vitamins Supplementation Can Improve Cognitive Functions and May Relate to the Enhancement of Transketolase Activity in A Rat Model of Cognitive Impairment Associated with High-fat Diets.

Rescue of Glycosylphosphatidylinositol-Anchored Protein Biosynthesis Using Synthetic Glycosylphosphatidylinositol Oligosaccharides.

Hypophosphatasia: Vitamin B6 status of affected children and adults.

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

The challenges of pregnancy management in pyridoxine nonresponsive homocystinuria: The Irish experience.

Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS.

A review of treatment modalities in gyrate atrophy of the choroid and retina (GACR).

Cognitive and neurological outcome of patients in the Dutch pyridoxine-dependent epilepsy (PDE-ALDH7A1) cohort, a cross-sectional study.

Monosodium Glutamate Induces Changes in Hepatic and Renal Metabolic Profiles and Gut Microbiome of Wistar Rats.

A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure.

Vitamin B6 deficiency with normal plasma levels of pyridoxal 5'-phosphate in perinatal hypophosphatasia.

Concurrent zinc and vitamin B6 deficiencies in acutely exacerbated inflammatory bowel disease: Case reports.

Classical homocystinuria, is it safe to exercise?

Novel Treatment for Congenital Disorder of Glycosylation in a Patient with Novel Homozygote Mutation of PMM2: A Case Report and Review Literature.

Early-onset vitamin B6-dependent epilepsy due to pathogenic PLPBP variants in a premature infant: A case report and review of the literature.