Lamin A/C in health, laminopathies, and familial partial lipodystrophy 2.

Metabolic Dysregulation in Laminopathies: Implications for Heart Failure and Cardiac Health.

P18 ZMPSTE24 variant with the lethal phenotype of restrictive dermopathy.

Autosomal-Recessive LMNA Dilated Cardiomyopathy.

The impact of alterations in lamin A on genome integrity.

Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single-Arm Meta-Analysis.

Genetically Confirmed Familial Case of Nonsyndromic Cardiac Progeria Caused by the LMNA p.Asp300Asn Variant with Presumed Gonadal Mosaicism: Phenotypic Comparison with Previously Reported Patients.

Reduced ZMPSTE24 expression leads to prelamin accumulation and development of steatosis in MASLD patients.

Rare clinical convergence: pulmonary sarcoidosis with dilated cardiomyopathy and central myopathy.

Inner Retina Changes in ABCA4-Related Retinopathy: Structure-Function Relationship.

LeDucq-funded programme: from pathomechanisms to personalized therapy of cardio-laminopathy.

Nuclear-lamin-guided plastic positioning and folding of the human genome.

Drosophila as a Model for Studying the Roles of Lamins in Normal Tissues and Laminopathies.

Reciprocated tachycardias in cardiac laminopathy: a clinical case report.

Sterile inflammation in laminopathies.

Unusual course of outflow tract tachycardia and cardiac decompensation in childhood: a case report and review of the literature.

Progeroid features in a patient with Malouf syndrome due to a rare LMNA variant: a case report and review of the literature.

Variant-Specific Late Gadolinium Enhancement Patterns Influence Clinical Outcomes in LMNA-Related Cardiomyopathy.

Pathological α-synuclein perturbs nuclear integrity.

National survey of Hutchinson-Gilford progeria syndrome and progeroid laminopathy in Japan.

Clustering cell nuclei on microgrooves for disease diagnosis using deep learning.

Genotype-guided cardiac device intervention in LMNA-related cardiac conduction disorder: The need for timely genetic testing.

[New pathogenic mutation in LMNA gene: Clinical case of familial cardiomyopathy].

Lamin AC Cardiomyopathy, the Next Masquerader: Laminopathy Mimicking Cardiac Sarcoidosis.

Downregulation of Nesprin1 by Runx2 deficiency is critical for the development of skeletal laminopathy-like pathology.

Familial cardiac laminopathy with predominant atrial involvement: a case series of a family with LMNA mutation.

The role of inner nuclear membrane protein emerin in myogenesis.

Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster.

Homozygous loss of function variant in LMNB2 gene causes major brain malformation and perinatal death.

Radiation symptoms resemble laminopathies and the physical underlying cause may sit at the lamin A C-terminus.

The Basis of Diversity in Laminopathy Phenotypes Caused by Variants in the Intron 8 Donor Splice Site of the LMNA Gene.

Micro-Scale Topography Triggers Dynamic 3D Nuclear Deformations.

Atrial standstill phenomenon in a non-dilated cardiomyopathy phenotype of a genetically confirmed laminopathy.

Much More Than a Stroke: Emery-Dreifuss Muscular Dystrophy Type 2 Revealed by Ischemic Stroke.

Case Report: Concurrent de novo pathogenic variants in the LMNA gene as a cause of sporadic partial lipodystrophy.

When Off-Target Is the Target: Treating Noncardiomyocytes in Cardiac Laminopathy.

Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells.

Disorganized chromatin hierarchy and stem cell aging in a male patient of atypical laminopathy-based progeria mandibuloacral dysplasia type A.

Cardiac laminopathy in familial partial lipodystrophy type 2 secondary to variants in the LMNA gene.

Post-COVID Myocarditis in Patients with Primary Cardiomyopathies: Diagnosis, Clinical Course and Outcomes.

Targeting Caspases 3/6 and Cathepsins L/B May Decrease Laminopathy-Induced Apoptosis in Alzheimer's Disease.

Clinical and Genetic Heterogeneity of Nuclear Envelopathy Related Muscular Dystrophies in an Indian Cohort.

A case of restrictive dermopathy in a Hutterite newborn: Diagnosis and creative skin-directed management.

Troponin T Assessment Allows for Identification of Mutation Carriers among Young Relatives of Patients with LMNA-Related Dilated Cardiomyopathy.

Congenital LMNA-Related Muscular Dystrophy in Paediatrics: Cardiac Management in Monozygotic Twins.

Creatine and L-carnitine attenuate muscular laminopathy in the LMNA mutation transgenic zebrafish.

Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice.

Eliminating elevated p53 signaling fails to rescue skeletal muscle defects or extend survival in lamin A/C-deficient mice.

How to Screen and Manage Suspected Laminopathy.

The Influence of a Genetic Variant in CCDC78 on LMNA-Associated Skeletal Muscle Disease.

A novel deep intronic variant in LAMA2 identified by RNA sequencing.

From gene to mechanics: a comprehensive insight into the mechanobiology of LMNA mutations in cardiomyopathy.

Cardiomyopathy with an LMNA Genetic Variant Affecting Three Consecutive Generations: A Case Series.

LMNA R644C associates with hepatic steatosis in a large cohort and increases cellular lipid droplet accumulation in vitro.

Interatrial block as a first clinical presentation of atrial cardiomyopathy related to a novel LMNA variant: a case report.

A silent interweaving: interatrial block and laminopathy.

COMPREHENSIVE CARDIOVASCULAR THERAPY IN EMERY-DREIFUSS MUSCULAR DYSTROPHY: A CASE REPORT.

The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B.

How nuclear envelope dynamics can direct laminopathy phenotypes.

Magnetic resonance imaging-based criteria to differentiate dysferlinopathy from other genetic muscle diseases.

Long lifetime and tissue-specific accumulation of lamin A/C in Hutchinson-Gilford progeria syndrome.

Naturally occurring canine laminopathy leading to a dilated and fibrosing cardiomyopathy in the Nova Scotia Duck Tolling Retriever.

An alpha-helix variant p.Arg156Pro in LMNA as a cause of hereditary dilated cardiomyopathy: genetics and bioinfomatics exploration.

Intermediate, but not average: The unusual lives of the nuclear lamin proteins.

A common variant that alters SUN1 degradation associates with hepatic steatosis and metabolic traits in multiple cohorts.

SUMO protease SENP6 protects the nucleus from hyperSUMOylation-induced laminopathy-like alterations.

Nuclear proteostasis imbalance in laminopathy-associated premature aging diseases.

A subtype of laminopathies: Generalized lipodystrophy-associated progeroid syndrome caused by LMNA gene c.29C>T mutation.

First human implant of the cardiac contractility modulation in patient with dilated cardiomyopathy-related laminopathy.

A Clinical Diagnosis of Laminopathy without Systolic Dysfunction: When Does Nuclei Malformation Start?

Novel Phenotype of LMNA Variant c.154C>G Affecting Heart, Liver, and Lipid and Iron Metabolism: A Case Report.

A Case of Cardiogenic Stroke With a Novel LMNA Variant (c. 1135C>A; p.Leu379Ile).

Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases.

The Interplay between Oxidative Stress and the Nuclear Lamina Contributes to Laminopathies and Age-Related Diseases.

A Genetically Confirmed Case of Laminopathy: Clues from the Clinical Picture and Muscle Biopsy.

Lem2 is essential for cardiac development by maintaining nuclear integrity.

Reevaluating the cause of laminopathy in Alzheimer's disease.

InterLINCing Chromatin Organization and Mechanobiology in Laminopathies.

LMNA-related muscular dystrophy: Identification of variants in alternative genes and personalized clinical translation.

Genomic analysis of a novel pathogenic variant in the gene LMNA associated with cardiac laminopathies found in Ecuadorian siblings: A case report.

The Molecular and Cellular Basis of Hutchinson-Gilford Progeria Syndrome and Potential Treatments.

Nuclear mechanosignaling in striated muscle diseases.

Enhanced Expression of a Novel Lamin A/C Splice Variant in Idiopathic Pulmonary Fibrosis Lung.

The Nuclear Envelope in Ageing and Progeria.

LMNA Co-Regulated Gene Expression as a Suitable Readout after Precise Gene Correction.

Redistribution of lamina-associated domains reshapes binding of pioneer factor FOXA2 in development of nonalcoholic fatty liver disease.

Aberrant chromatin organization at the nexus of laminopathy disease pathways.

Timing of cardioverter-defibrillator implantation in patients with cardiac laminopathies-External validation of the LMNA-risk ventricular tachyarrhythmia calculator.

Lipoatrophic diabetes in familial partial lipodystrophy type 2: From insulin resistance to diabetes.

Restrictive dermopathy: A baby with taut skin, facial dysmorphism, joint contractures, and pulmonary hypoplasia.

Disease progression rate is a strong predictor of ventricular arrhythmias in patients with cardiac laminopathies: a primary prevention cohort study.

[A case report of laminopathy-cardiomyopathy].

Genotype Complements the Phenotype: Identification of the Pathogenicity of an LMNA Splice Variant by Nanopore Long-Read Sequencing in a Large DCM Family.

The E262K mutation in Lamin A links nuclear proteostasis imbalance to laminopathy-associated premature aging.

LMNA mutation leads to cardiac sodium channel dysfunction in the Emery-Dreifuss muscular dystrophy patient.

Personalized Medicine Approach in a DCM Patient with LMNA Mutation Reveals Dysregulation of mTOR Signaling.

IFN-Aging: Coupling Aging With Interferon Response.

The most severe form of LMNA-associated congenital muscular dystrophy.

Genetic Appraisal of Hereditary Muscle Disorders In A Cohort From Mumbai, India.

Lamin A and telomere maintenance in aging: Two to Tango.

Post-Translational Modification of Lamins: Mechanisms and Functions.

Effect of Occurrence of Lamin A/C (LMNA) Genetic Variants in a Cohort of 101 Consecutive Apparent "Lone AF" Patients: Results and Insights.

MDS/AML with del5q: An acquired "laminopathy"?

Autophagy-mediated plasma membrane removal promotes the formation of epithelial syncytia.

Emerin self-assembly and nucleoskeletal coupling regulate nuclear envelope mechanics against stress.

Diurnal shift of mouse activity by the deficiency of an ageing-related gene Lmna.

The wide and growing range of lamin B-related diseases: from laminopathies to cancer.

DNA methylation signatures in Blood DNA of Hutchinson-Gilford Progeria syndrome.

Heterozygous LMNA mutation-carrying iPSC lines from three cardiac laminopathy patients.

Lethal Restrictive Dermopathy with ZMPSTE24 Mutation.

Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer's disease.

Laminopathies: should Wenckebach be a cause for concern? A case report.

Familial atrial myopathy in a large multigenerational heart-hand syndrome pedigree carrying an LMNA missense variant in rod 2B domain (p.R335W).

Predictors of mortality and cardiovascular outcomes in Emery-Dreifuss muscular dystrophy in a long-term follow-up.

Clinical Features of LMNA-Related Cardiomyopathy in 18 Patients and Characterization of Two Novel Variants.

Preclinical Advances of Therapies for Laminopathies.

In Silico and In Vivo Analysis of Amino Acid Substitutions That Cause Laminopathies.

Molecular Pathology of Laminopathies.

[When oncology research opens a path toward a therapy for a laminopathy].

Restrictive dermopathy: Three new patients with ZMPSTE24 mutations and a review of the literature.

Super-Resolution Imaging of the A- and B-Type Lamin Networks: A Comparative Study of Different Fluorescence Labeling Procedures.

Importance of clinical suspicion and multidisciplinary management for early diagnosis of a cardiac laminopathy patient: A case report.

A CRISPR/Cas9 zebrafish lamin A/C mutant model of muscular laminopathy.

[A case of laminopathy with the mutation of LMNA gene identified by the exome analysis of disease-related genes].

Management of heart failure with concomitant complete atrioventricular block caused by a novel missense LMNA mutation.

A novel biallelic LMNB2 variant in a patient with progressive myoclonus epilepsy and ataxia: A case of laminopathy.

Establishment of a novel human iPSC line (YCMi003-A) from a patient with dilated cardiomyopathy carrying genetic variant LMNA p.Asp364His.

Oxidative Stress and Mitochondrial Dysfunction Associated with Peripheral Neuropathy in Type 1 Diabetes.

AIMP3 induces laminopathy and senescence of vascular smooth muscle cells by reducing lamin A expression and leads to vascular aging in vivo.

DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies.

THE NUCLEUS: Mechanosensing in cardiac disease.

International retrospective natural history study of LMNA-related congenital muscular dystrophy.

Expression of the Ebola Virus VP24 Protein Compromises the Integrity of the Nuclear Envelope and Induces a Laminopathy-Like Cellular Phenotype.

Components and Mechanisms of Nuclear Mechanotransduction.

Case Report: An Atypical Form of Familial Partial Lipodystrophy Type 2 Due to Mutation in the Rod Domain of Lamin A/C.

Floppy infant syndrome as a first manifestation of LMNA-related congenital muscular dystrophy.

Establishment of an iPSC line (JSPHi001-A) from a patient with familial dilated cardiomyopathy and atrial fibrillation caused by LMNA missense mutation (c.1003C > T).

Persistent atrial fibrillation ablation in cardiac laminopathy: Electrophysiological findings and clinical outcomes.

The progeria research foundation 10th international scientific workshop; researching possibilities, ExTENding lives - webinar version scientific summary.

Cardiac Arrhythmias in Muscular Dystrophies Associated with Emerinopathy and Laminopathy: A Cohort Study.

Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.

Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair.

Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes.

Cardiac phenotype in familial partial lipodystrophy.

Targeting the histone demethylase LSD1 prevents cardiomyopathy in a mouse model of laminopathy.

Epigenetic reprogramming to prevent genetic cardiomyopathy.

Clinical and Genomic Evaluation of 207 Genetic Myopathies in the Indian Subcontinent.

Decreased mechanotransduction prevents nuclear collapse in a Caenorhabditis elegans laminopathy.

Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy.

Nuclear lamin phosphorylation: an emerging role in gene regulation and pathogenesis of laminopathies.

Hutchinson-Gilford Progeria Syndrome: Clinical and Molecular Characterization.

Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology.

Molecular and Mechanobiological Pathways Related to the Physiopathology of FPLD2.

LMNA Missense Mutation Causes Nonsense-Mediated mRNA Decay and Severe Dilated Cardiomyopathy.

Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis.

Structural and Mechanical Aberrations of the Nuclear Lamina in Disease.

Cardiovascular Involvement in Pediatric Laminopathies. Report of Six Patients and Literature Revision.

Nuclear Membrane Rupture and Its Consequences.

Progress and trends in the development of therapies for Hutchinson-Gilford progeria syndrome.

Cytokine Profile in Striated Muscle Laminopathies: New Promising Biomarkers for Disease Prediction.

Hypopharyngeal Squamous Cell Carcinoma in Sisters with LMNA Associated Familial Partial Lipodystrophy: A Case Report and Review of the Literature.

Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency.

Lamin A/C Mechanotransduction in Laminopathies.

Consequences of Lmna Exon 4 Mutations in Myoblast Function.

Genotype-phenotype analysis of LMNA-related diseases predicts phenotype-selective alterations in lamin phosphorylation.

Can Circulating Cardiac Biomarkers Be Helpful in the Assessment of LMNA Mutation Carriers?

RNA Sequence Analyses throughout the Course of Mouse Cardiac Laminopathy Identify Differentially Expressed Genes for Cell Cycle Control and Mitochondrial Function.

Left-ventricular innervation assessed by 123I-SPECT/CT is associated with cardiac events in inherited arrhythmia syndromes.

Pulmonary vein isolation treats symptomatic AF in a patient with Lamin A/C mutation: case report and review of the literature.

Loss of an H3K9me anchor rescues laminopathy-linked changes in nuclear organization and muscle function in an Emery-Dreifuss muscular dystrophy model.

Case reports of a c.475G>T, p.E159* lamin A/C mutation with a family history of conduction disorder, dilated cardiomyopathy and sudden cardiac death.

Emery-Dreifuss muscular dystrophy.

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering.

ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy.

Lamin A/C Cardiomyopathy: Implications for Treatment.

Differences in cardiac phenotype and natural history of laminopathies with and without neuromuscular onset.

Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome.

Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy.

Regulation of inner nuclear membrane associated protein degradation.

A new laminopathy caused by an Arg133/Leu mutation in lamin A/C and the effects thereof on adipocyte differentiation and the transcriptome.

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy.

Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome.

Rare BANF1 Alleles and Relatively Frequent EMD Alleles Including 'Healthy Lipid' Emerin p.D149H in the ExAC Cohort.

Endoplasmic reticulum stress at the crossroads of progeria and atherosclerosis.

Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients.

Deciphering Nuclear Mechanobiology in Laminopathy.

Structural instability of lamin A tail domain modulates its assembly and higher order function in Emery-Dreifuss muscular dystrophy.

Loss of CRWN Nuclear Proteins Induces Cell Death and Salicylic Acid Defense Signaling.

Hutchinson-Gilford Progeria Syndrome-Current Status and Prospects for Gene Therapy Treatment.

Induced Pluripotent Stem Cells to Study Mechanisms of Laminopathies: Focus on Epigenetics.

A novel case of Greenberg dysplasia and genotype-phenotype correlation analysis for LBR pathogenic variants: An instructive example of one gene-multiple phenotypes.

Lamin A/C gene (LMNA) mutation associated with laminopathy: A rare cause of idiopathic acro-osteolysis.

Assessment of fibroblast nuclear morphology aids interpretation of LMNA variants.

Modeling Skeletal Muscle Laminopathies Using Human Induced Pluripotent Stem Cells Carrying Pathogenic LMNA Mutations.

Dissecting cellular mechanics: Implications for aging, cancer, and immunity.

Cardiometabolic assessment of lamin A/C gene mutation carriers: a phenotype-genotype correlation.

Complex effects of laminopathy mutations on nuclear structure and function.

Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling.

A novel LMNA mutation identified in a Japanese patient with LMNA-associated congenital muscular dystrophy.