Um tipo de linfoma não Hodgkin de crescimento lento, que se desenvolve fora dos gânglios linfáticos. Ele é formado por pequenos linfócitos B. O aparelho digestório é o local mais comum onde ele se manifesta. Outros locais comuns onde pode surgir incluem: pulmão, cabeça e pescoço, região dos olhos (como pálpebras), pele, tireoide e mama. Quando afeta o estômago, está associado à presença da infecção por H. pylori.
Introdução
O que você precisa saber de cara
Um tipo de linfoma não Hodgkin de crescimento lento, que se desenvolve fora dos gânglios linfáticos. Ele é formado por pequenos linfócitos B. O aparelho digestório é o local mais comum onde ele se manifesta. Outros locais comuns onde pode surgir incluem: pulmão, cabeça e pescoço, região dos olhos (como pálpebras), pele, tireoide e mama. Quando afeta o estômago, está associado à presença da infecção por H. pylori.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 6 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 20 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
5 genes identificados com associação a esta condição. Padrão de herança: Multigenic/multifactorial, Not applicable.
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canon
CytoplasmNucleus
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation (PubMed:10187770, PubMed:10364242, PubMed:10400625, PubMed:24074955, PubMed:25365219). Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokin
Cytoplasm, perinuclear regionMembrane raft
Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines (PubMed:11262391, PubMed:18264101, PubMed:24074955). Mediates BCL10 cleavage: MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen rec
Cytoplasm, perinuclear regionNucleus
Immunodeficiency 12
A primary immunodeficiency characterized by onset in infancy of recurrent bacterial and candidal infections resulting in bronchiectasis and growth delay. Manifestations include mastoiditis, aphthous ulcers, cheilitis, gingivitis, esophagitis, gastritis, duodenitis, and meningitis. Levels of absolute lymphocytes and serum immunoglobulins are normal, but specific antibody titers are low despite immunization, and T-cells show impaired proliferative responses to mitogens.
Transcriptional repressor (PubMed:18347093, PubMed:26647308). Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity). Plays an important role in the specification and differentiation of lung epithelium. Acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program; the function may involve regulation of AGR2. Essential transcriptional regulator of B-cell development. I
Nucleus
Variantes genéticas (ClinVar)
509 variantes patogênicas registradas no ClinVar.
Vias biológicas (Reactome)
21 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Linfoma MALT
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
🟢 Recrutando agora
2 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.
Outros ensaios clínicos
864 ensaios clínicos encontrados, 2 ativos.
Publicações mais relevantes
Mostrando amostra de 200 publicações de um total de 1.493
Which quadruple therapy should be prescribed as first-line treatment for Helicobacter pylori infection? Results of a prospective study comparing concomitant and bismuth therapy.
Helicobacter pylori (H. pylori) infection is a major global health concern associated with peptic ulcer disease, chronic gastritis, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric cancer. Rising antibiotic resistance, particularly to clarithromycin and metronidazole, has reduced the efficacy of standard triple therapy, prompting guidelines to recommend quadruple regimens. This study aimed to compare the efficacy, safety, and patient adherence of concomitant quadruple therapy (QC-14) versus bismuth-based quadruple therapy (QB-10) as first-line treatments in a Moroccan population. In this prospective, randomized study, 86 adult outpatients with H. pylori infection confirmed by active diagnostic tests (histology, 13C-urea breath test, or stool antigen test) were enrolled between January and June 2024 at two university hospitals in Casablanca, Morocco. Patients initially identified by serology were included only if infection was subsequently confirmed by an active test. Participants were randomized to receive either QC-14 (omeprazole, amoxicillin, clarithromycin, metronidazole for 14 days) or QB-10 (omeprazole, bismuth subsalicylate, tetracycline, metronidazole for 10 days). Eradication was assessed 4-6 weeks post-treatment. Safety, adverse events, and adherence were evaluated. Baseline characteristics were similar between groups. Endoscopy was performed in 69.7 % of patients, revealing erythematous gastritis in 91.6 % and peptic ulcer disease in 8.3 %. Eradication rates were 79.5 % for QB-10 and 76.1 % for QC-14 (p = 0.53). Adverse events occurred in 31.8 % (QB-10) and 23.8 % (QC-14) (p = 0.776); diarrhea was more frequent in QC-14 (15 %), while discolored stools were reported only in QB-10 (18.2 %). Adherence exceeded 93 % in both groups. Both concomitant and bismuth quadruple therapies are effective, safe, and well-tolerated first-line treatments for H. pylori eradication, achieving > 75 % eradication rates. The choice of regimen may depend on local resistance patterns, cost, and patient-specific factors. Further multicenter studies with resistance profiling are warranted.
Silent imposter in pneumonic attire: primary pulmonary MALT lymphoma.
Primary pulmonary lymphoma (PPL) is a rare extranodal lymphoma confined to the lungs, accounting for <1% of non-Hodgkin lymphomas. We describe a man in his early 30s presenting with progressive dyspnoea, fever and productive cough, initially treated as pneumonia. Despite multiple antibiotic courses, radiological lesions persisted. Histopathology and immunohistochemistry from transbronchial lung biopsy revealed extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue. PET-CT confirmed localised pulmonary involvement, fulfilling criteria for PPL. The patient responded to rituximab-bendamustine chemoimmunotherapy with clinical improvement. This case highlights the importance of considering rare malignancies in non-resolving pulmonary consolidations.
Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation.
Primary cutaneous B-cell lymphoma encompass clinically heterogeneous entities. While primary cutaneous diffuse large B-cell lymphoma, leg type (pcDLBCL-LT) is aggressive, primary cutaneous follicle centre lymphoma (pcFCL) and primary cutaneous marginal zone lymphoma (pcMZL) typically follow an indolent course. To clarify their pathophysiological basis, we perform single-cell RNA sequencing on pcFCL, pcMZL, and pcDLBCL-LT, alongside reactive B-cell rich lymphoid proliferations (rB-LP), gastric mucosa-associated lymphoid tissue (MALT) lymphoma, and systemic counterparts. Here we show that the indolent pcMZL, pcFCL, and rB-LP exhibit a persistent germinal centre reaction, not observed in pcDLBCL-LT or gastric MALT lymphoma. Further, pcMZL top expanded clones develop within lesions from naïve and not post-germinal centre B cells as currently presumed. Our data thus indicate that pcMZL and pcFCL, similar to rB-LP may be driven by (a yet unknown) antigen. While our data indicates that pcFCL exhibits some features of true lymphomas, it clearly supports the classification of pcMZL as a lymphoproliferative disease.
Esophageal, gastric and duodenal Crohn's disease in the biologic era: Results from a retrospective observational nationwide study of GETECCU.
Crohn's disease (CD) affecting the esophagus, stomach, and duodenum (upper CD [UCD]) is a rare phenotype, and data on its outcomes and treatment response are limited. We conducted a multicenter retrospective study of adult patients diagnosed with UCD between January 2000 and December 2019, with ≥ 1 year of follow-up. Extensive CD (ECD) was defined as concomitant jejunal, ileal and/or colonic involvement. One hundred ninety-seven UCD patients were included with a median follow-up of 10.7 years (IQR 5.7-14.2). Only nine (4.6%) had isolated UCD. The inflammatory phenotype predominated, with aphthous ulcers as the main endoscopic lesion (42%). Systemic corticosteroids and thiopurines were the most frequently prescribed therapies after UCD diagnosis. At weeks 14 and 52, response and remission rates for UCD and ECD were similar for all treatments, except higher rates with thiopurines and infliximab in UCD at both time points (p < 0.05). Ten (5.1%) patients shifted phenotype over time (most from inflammatory to stricturing). Two patients developed neoplasia (one gastric MALT lymphoma, one esophageal carcinoma). Upper gastrointestinal involvement in adult CD does not appear to alter immunosuppressive therapeutic needs compared with ECD requirements.
Pediatric Orbital MALT Lymphoma Masquerading as a Pyogenic Granuloma.
This case report discusses a diagnosis of B-cell lymphoma mucosa-associated lymphoid tissue (MALT) in the conjunctiva of a young boy who presented with a painless, enlarging conjunctival mass.
Publicações recentes
Clinicopathological and Imaging Distinction Between Ocular Adnexal MALT Lymphoma and IgG4-Related Ophthalmic Disease.
📖 RevisãoSurvival outcomes and prognostic nomogram for primary pulmonary MALT lymphoma and diffuse large B-cell lymphoma: A SEER database study.
[Endoscopic characteristics of primary gastric lymphoma and prediction of treatment response].
DNA-based characterization of primary hepatic MALT lymphoma reveals a rare FAT3 missense variant and Hippo pathway activation: a case report and literature review.
Treatment and outcomes of pulmonary mucosa-associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients.
📚 EuropePMC1.415 artigos no totalmostrando 199
Editor's Note: The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways.
Cancer research communicationsA case of pulmonary mucosa-associated lymphoid tissue lymphoma with plasmacytic differentiation and amyloid deposition: case report and literature review.
Frontiers in oncologyPrimary MALT lymphoma in the terminal ileum, ileocecal region and ascending colon.
Clinics and research in hepatology and gastroenterologySingle-cell atlas of B cell heterogeneity in lacrimal IgG4-related disorders: Unraveling the transition from inflammatory exhaustion to clonal malignancy.
The FEBS journalPrimary Thyroid Lymphoma: A Report of Three Cases and a Review of the Literature.
CureusPrimary extranodal marginal zone non-hodgkin lymphoma of the prostate: a case report.
Frontiers in oncologyWhich quadruple therapy should be prescribed as first-line treatment for Helicobacter pylori infection? Results of a prospective study comparing concomitant and bismuth therapy.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of GastroenterologyMetachronous multiple primary cancers involving pulmonary non-Hodgkin lymphoma and bladder cancer: a case report.
Frontiers in oncologyExtranodal Marginal Zone B-cell Lymphoma Presenting as a Painless Buccal Mass in the Masticator Space.
Journal of medical casesComparative pathogenesis and management of orbital/conjunctival and gastric MALT lymphoma: Microbial drivers, molecular mechanisms, and therapeutic implications.
Survey of ophthalmologyPrognostic impact of cancer-directed surgery in primary pulmonary lymphoma: a population-based, propensity score-matched analysis.
Translational cancer researchRare and Elusive: The Challenges of Bronchoscopically Diagnosing Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma.
Case reports in pulmonologyThe Impact of Surgical Intervention on The Survival of Primary Head and Neck MALT Lymphoma.
OncologySystemic, asymptomatic skeletal muscle infiltration by MALT lymphoma: Defining a 'silent infiltrator' phenotype with 18F-FDG PET/CT.
Leukemia research reportsUltrasonographic differentiation of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue lymphoma in primary thyroid lymphoma.
Frontiers in endocrinologyApplication of artificial intelligence in differentiating IgG4-related ophthalmic disease and orbital MALT lymphoma: a review of radiomics and deep learning advances.
Frontiers in immunologyDeep learning-based diagnostic model for ocular surface neoplastic diseases.
American journal of ophthalmologyUnusual case of follicular lymphoma of vocal cord.
Virchows Archiv : an international journal of pathology[Updates in marginal zone lymphomas].
Annales de pathologieDiagnostic Challenge of Extranodal Marginal Zone Lymphoma of Extraocular Muscles: A Case Report.
Reports (MDPI)Safe Bronchoscopic Treatment Strategy for Subglottic Severe Airway Stenosis: A Case Report of Tracheal MALT Lymphoma.
Respirology case reportsFirst comprehensive characterization of lip lymphoma: a population-based study.
Acta haematologicaPrimary Mucosa-Associated Lymphoid Tissue Lymphoma of the Lung: A Case Report.
Journal of the Korean Society of RadiologyPulmonary Mucosa-Associated Lymphoid Tissue Lymphoma and Tuberculosis: A Rare Association With Diagnostic and Therapeutic Challenges.
Journal of medical casesSurvival outcomes of eyelid lymphoma: a SEER database analysis.
Orbit (Amsterdam, Netherlands)Analysis of the pathological composition ratio of orbital space-occupying lesions in 7 515 cases: single-center retrospective study.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologieSilent imposter in pneumonic attire: primary pulmonary MALT lymphoma.
BMJ case reportsIndolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation.
Nature communicationsProgressive Bilateral Localised Amyloidosis of the Eyelids and Conjunctiva Four Years after MALT Lymphoma: A Case Report.
Klinische Monatsblatter fur AugenheilkundeAFI-Guided Detection and Biopsy of Pulmonary MALT Lymphoma With Bilateral Endobronchial Involvement.
Respirology case reportsEsophageal, gastric and duodenal Crohn's disease in the biologic era: Results from a retrospective observational nationwide study of GETECCU.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the LiverDiscriminating orbital lymphoma from inflammation and correlating with histopathology using microstructure-based time-dependent diffusion MRI.
European journal of radiologyBilateral orbital masses caused by IgG4-expressing MALT lymphoma in the right side and IgG4-related ophthalmic disease in the left side: A case report.
Modern rheumatology case reportsThe Role of Imaging Techniques in the Evaluation of Extraglandular Manifestations in Patients with Sjögren's Syndrome.
Diagnostics (Basel, Switzerland)Conservative Management of Primary Thyroid Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Case Report and Review of Multidisciplinary Approach.
CureusAtypical orbital mucosa-associated lymphoid tissue lymphoma involving the inferior rectus in a young adult: A case report and literature review.
MedicineMucosa-associated lymphoid tissue lymphoma with monoclonal T-cell expansion.
Virchows Archiv : an international journal of pathologyAutoimmune disease-associated lymphomas: research progress and review.
Frontiers in immunologyRadiotherapy is associated with improved survival in stage I-II gastric MALT lymphoma after failed or inadequate Helicobacter pylori eradication: a single-center retrospective study.
Frontiers in oncologyDeciphering the molecular landscape of Sjögren's disease, mucosa-associated lymphoid tissue lymphoma, and thyroid cancer: unraveling the complexities of disease mechanisms and diagnostic biomarkers.
Clinical rheumatology[A Case of Gallbladder MALT Lymphoma].
Gan to kagaku ryoho. Cancer & chemotherapyPediatric Orbital MALT Lymphoma Masquerading as a Pyogenic Granuloma.
JAMA ophthalmologyNon-gastric mucosa-associated lymphoid tissue lymphomas: a narrative review of pathogenesis, diagnosis, and treatment strategies.
Annals of translational medicineDefinitive 24 Gy radiotherapy for stage IE gastric MALT lymphoma: large-scale validation of an optimal dose with reduced acute toxicity.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer AssociationPrimary Gastrointestinal B-Cell Lymphomas: A Clinicopathological Review.
Journal of hematologyDiagnostic challenges and management strategies of pulmonary mucosa-associated lymphoid tissue lymphoma: a case report and literature review.
Frontiers in medicineClinicopathological analysis of 34 cases of extraocular muscle space-occupying lesions.
Scientific reportsPrimary Breast MALT Lymphoma: Clinical Features and Outcomes From a Single-Institution Experience at Mayo Clinic.
American journal of hematologyCurrent concepts of Helicobacter pylori infection.
European journal of medical researchMucosal-Associated Lymphoid Tissue Lymphoma in Southeast Asia: A 15-Year Retrospective Multicenter Study.
Hematology reportsDiffuse thyroid enlargement and its regression in methotrexate-associated lymphoproliferative disorder: an ultrasonographic observation.
Endocrinology, diabetes & metabolism case reportsClinical management of gastric mucosa-associated lymphoid tissue lymphoma.
The Korean journal of internal medicinePrognostic outcome of extranodal marginal zone B-cell lymphoma: a nationwide cohort.
Scientific reportsClinical characteristics and long-term prognosis of primary mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma in the small intestine.
Translational cancer researchCharacteristics of pulmonary lymphoma on baseline 18F-FDG positron emission tomography/computed tomography and their clinical value in predicting treatment response.
Quantitative imaging in medicine and surgeryCystic Fluorodeoxyglucose-Avid Thymic Hyperplasia with Lymphoepithelial Sialadenitis-like Features.
Interdisciplinary cardiovascular and thoracic surgeryPrimary thyroid lymphoma: a tertiary-center experience.
Endokrynologia PolskaHigher incomplete remission rate of ocular extranodal marginal zone B-cell lymphoma in hepatitis B virus infectious patients.
Orbit (Amsterdam, Netherlands)Extranodal MALT lymphoma masquerading as a cavernous hemangioma: A diagnostic and surgical challenge.
Radiology case reportsInvasive Lobular Carcinoma of the Breast With Imaging Features Resembling Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report.
CureusSequential Gastric MALT Lymphoma and Early Signet Ring Cell Adenocarcinoma in a Patient With Chronic Hepatitis B and Prior Helicobacter pylori Infection.
ACG case reports journalClinical characteristics and survival outcomes of thymic mucosa-associated lymphoid tissue lymphoma: A multicenter analysis of 82 patients.
CancerA Rare Case of Subglottic Malignant Lymphoma Requiring Emergency Tracheostomy.
CureusEfficacy and Safety of <em>Saccharomyces Boulardii</em> with Standard Quadruple Therapy for Eradication of <em>Helicobacter Pylori </em>in Adults: Meta-Analysis.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSPA Report of Two Cases of Primary Mucosa-Associated Lymphoid Tissue Lymphoma of the Pharynx, Larynx, and Trachea.
Clinical case reportsRole of 18F-FDG PET/CT in the diagnosis and treatment response assessment of primary pulmonary lymphoma.
Translational cancer researchSurvival Outcomes and Treatment Strategies in Primary Thyroid Lymphoma: A Population-Based Study of 401 Cases from the Tokyo Cancer Registry.
Thyroid : official journal of the American Thyroid AssociationThe Value of Punching It Out: Patient With Cowden Syndrome and MALT Lymphoma of the Lung.
Case reports in oncological medicineConcurrent esophageal squamous cell carcinoma with gastric mucosa-associated lymphoid tissue lymphoma: a case report.
Frontiers in oncologySynchronous Primary Pleural Mucosa-Associated Lymphoid Tissue Lymphoma and Pulmonary Squamous Cell Carcinoma in a Patient With Asbestos Exposure: A Case Report.
CureusPulmonary Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Diagnostic Dilemma.
Respirology case reportsCorrelation Between Gastric and Gallbladder Helicobacter pylori Infection in South Indian Patients Undergoing Cholecystectomy for Gallbladder Disease.
CureusValue of endoscopic submucosal dissection in diagnosing gastric mucosa-associated lymphoid tissue lymphoma: A case report.
World journal of gastroenterologyPathological profile of 1,385 lymphoma cases in Zunyi, China: A classification-based analysis following the WHO 2022 criteria for hematolymphoid tumors.
Virchows Archiv : an international journal of pathologyA Three-Way Comparison of Nodular Lesions in H. pylori-Induced Gastritis, Non-Helicobacter pylori Helicobacter (NHPH)-Induced Gastritis, and NHPH-Induced MALT Lymphoma Reveals Their Distinct Endoscopic Predictors: Distribution for Bacterial Etiology and Morphology for Malignancy.
HelicobacterKV11.1 (hERG1)-centered macromolecular membrane complexes regulate proliferation in B cell lymphomas and constitute novel pharmacological targets.
Pharmacological researchConjunctival Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma Associated With Methotrexate Therapy: A Case of Complete Remission Following Drug Discontinuation.
CureusReactive Intravascular Plasmablastic/Immunoblastic Proliferation in a Patient with Concurrent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma and Tuberculosis Potentially Mimicking Aggressive Intravascular Lymphoma: A Rare Case Report.
Case reports in gastroenterology[Watch-and-Wait and surveillance in gastric MALT-lymphoma after exclusive Helicobacter pylori eradication under special consideration of patients' compliance].
Zeitschrift fur GastroenterologieBilateral lacrimal gland MALT lymphoma incidentally detected on 68Ga-DOTATATE PET/CT: an unusual but noticeable finding.
Revista espanola de medicina nuclear e imagen molecularA prophylactic study of curcumin nanoparticle-induced bacterial ghosts against Helicobacter pylori in a C57BL/6 mouse model.
Microbial pathogenesisMucosa-Associated Lymphoid Tissue Lymphoma of the Stomach Associated with a Helicobacter heilmannii sensu stricto Infection One Year After the Successful Eradication of Helicobacter pylori.
Internal medicine (Tokyo, Japan)Combined diffusion-weighted MRI and contrast-enhanced ultrasonography in diagnosing small hepatic MALT lymphoma mimicking hepatocellular carcinoma.
Clinical journal of gastroenterologyA Rare Case of Thymic Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma.
CureusApplications of New Generation Sequencing (NGS) in Ocular Oncology.
International ophthalmology clinicsRare Endoscopic Presentation of Sigmoid Colon MALT Lymphoma.
Digestive diseases and sciencesOccult MALT lymphoma masquerading as benign cysts in Sjögren's syndrome: A case report of diagnostic dilemma.
International journal of surgery case reportsPanenteric Capsule Endoscopy in Young Patients with Suspected Irritable Bowel Syndrome: A Self-Controlled Feasibility Study.
Clinical and experimental gastroenterology[The Relationship between Ig Class Switch Recombination and MMR Protein, Microsatellite Phenotype in Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue].
Zhongguo shi yan xue ye xue za zhiMucosal healing of ileum-mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication: a case report and literature review.
Frontiers in oncologyCase Report: Two cases of primary pulmonary endobronchial extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue localized in the trachea and bronchus.
Frontiers in oncologySix-Year Remission With No Relapse After Four-Time Weekly Rituximab Only for Bilateral Ocular Adnexal Follicular Lymphoma.
CureusPrimary Hepatic Mucosa-Associated B-Cell Lymphoma in a Patient with Primary Sclerosing Cholangitis-A Case Ultimately Requiring Liver Transplantation.
Diagnostics (Basel, Switzerland)CXCR-4 -directed PET/CT examination in a case of marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma).
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der NuklearmedizinClinical utility of repeated IgH gene rearrangement testing for the diagnosis and surveillance of gastric MALT lymphoma.
Scientific reportsTegoprazan dual and quadruple therapy for Helicobacter pylori eradication: a prospective, randomized controlled trial in Beijing, China.
Frontiers in medicineRare Case Report of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma.
Respirology case reportsMALT lymphoma affecting the oral cavity: a clinical, pathologic and genetic study of MALT1 gene translocation.
Oral surgery, oral medicine, oral pathology and oral radiologyClinical evaluation of the aperture shape controller in volumetric modulated arc therapy: Effects on MLC and jaw motion complexity, plan quality, and deliverability.
Journal of applied clinical medical physicsCrystal-storing histiocytosis associated with MALT Lymphoma: a case report and literature review.
Annals of medicine and surgery (2012)Initial local treatment strategies on survival outcomes of early-stage breast mucosa-associated lymphoid tissue lymphoma.
Annals of hematologyInitial Treatment Strategies Show No Survival Difference in Early-Stage Salivary Gland Mucosa-Associated Lymphoid Tissue Lymphoma.
Journal of multidisciplinary healthcareEndonephrology: Evolving Techniques of Endoscopic Ultrasound in Diagnosing Renal Lymphoma.
ACG case reports journalIdentifying high-risk patients with MALT lymphoma undergoing first-line therapy for disease progression.
Expert review of hematologyA Systematic Review of the Outcomes of Mucosa-Associated Lymphoid Tissue Intracranial Lymphomas.
ANZ journal of surgeryNew workflow and motion analysis for gastric mucosa-associated lymphoid tissue lymphoma on a 1.5-T MR-Linac.
Technical innovations & patient support in radiation oncologyGene expression cluster differences and molecular correlation with the STING pathway in orbital MALT lymphoma and orbital IgG4-related eye disease.
Discover oncologyPrimary central nervous system mucosa-associated lymphoid tissue lymphoma: a diagnostic challenge.
BJR case reportsPrevalence and Diagnostic Comparison of Helicobacter pylori and Non-Helicobacter pylori Helicobacter Infections in Patients Undergoing Upper Gastrointestinal Endoscopy with Gastric Biopsy in Algarve, Portugal.
MicroorganismsThe role of probiotic supplementation in reducing Helicobacter pylori recurrence after classic quadruple therapy.
Frontiers in pharmacologyA Rare Presentation of Erosive Gastritis Caused by Helicobacter heilmannii Infection.
CureusAnalysis of Helicobacter pylori Infection Status and Clarithromycin-resistant Strains in Patients With Gastric Mucosa-associated Lymphoid Tissue Lymphoma Using Real-time Polymerase Chain Reaction: A Single-center Korean Study.
Journal of clinical gastroenterologyDosimetric evaluation of cone beam computed tomography-guided online adaptive radiotherapy in gastric mucosa-associated lymphoid tissue lymphoma.
Technical innovations & patient support in radiation oncologyRare presentation of ileal mucosa-associated lymphoid tissue lymphoma: a case of obstructive syndrome in a Moroccan patient.
Journal of surgical case reportsAtypical Optic Neuritis as a Manifestation of Ocular Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Case Report.
CureusPrimary renal mucosa-associated lymphoid tissue lymphoma coexisting with immune thrombocytopenia.
World journal of surgical oncologyHigh-density Lipoprotein Cholesterol and the Development of Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue.
Journal of cancer preventionPathologic Findings of Pulmonary Lymphoproliferative Disorders.
Seminars in ultrasound, CT, and MRPulmonary MALT lymphoma diagnosed with transbronchial lung cryobiopsy after unsuccessful transbronchial lung biopsy: a case report.
Frontiers in medicinePerilesional dominance: radiomics of multiparametric MRI enhances differentiation of IgG4-Related ophthalmic disease and orbital MALT lymphoma.
BMC medical imagingRisk and clinical implications of histological transformation in extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: A population-based analysis.
Scientific reportsIRTA1 expression in extranodal marginal zone (MALT) lymphoma is variable across anatomic sites.
American journal of clinical pathologyAn Epidemiological Study on Survival in Lymphoma of Mucosa-Associated Lymphoid Tissue: A Comparative Analysis by Primary Tumor Location.
Journal of investigative surgery : the official journal of the Academy of Surgical ResearchPredictors of survival in gastric mucosa-associated lymphoid tissue lymphoma: An updated surveillance, epidemiology, and end results-based analysis of age and gender disparities.
World journal of clinical oncologyThe clinical outcomes of ultra-low-dose radiotherapy for primary conjunctival mucosa-associated lymphoid tissue lymphoma.
International ophthalmologyA case of intestinal MALT lymphoma characterized by diffuse capillary hyperplasia nodules with hemorrhage.
Revista espanola de enfermedades digestivasPrimary mucosa associated lymphoid tissue lymphoma of the gallbladder: A case report and review of literature.
World journal of clinical casesCD5 expression in marginal zone lymphoma does not predict inferior outcome and has similarities to indolent lymphomas.
Blood neoplasiaTreatment approaches and clinical outcomes in primary colorectal MALT lymphoma: a single-institution retrospective study of 66 patients.
HaematologicaSynchronous MALT lymphoma and gastric adenocarcinoma.
Revista espanola de enfermedades digestivasCan Online Adaptive Radiation Therapy Eliminate Intrafractional Deformation in Gastric Mucosa-Associated Lymphoid Tissue Lymphoma?
Practical radiation oncologyPrimary Thyroid Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma: A Case Report.
CureusConcurrent chronic follicular conjunctivitis and conjunctival MALT lymphoma potentially caused by Chlamydia pneumoniae.
IDCasesThe Role of the Gut Microbiome in Non-Hodgkin Lymphoma (NHL): A Focus on Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Cutaneous T-Cell Lymphoma, and NK/T-Cell Lymphoma.
CancersClinical and imaging features of primary thyroid MALT lymphoma.
Frontiers in oncologyPathological Findings, Clinical Characteristics, and Outcomes of Thyroid Lymphomas: A Single Tertiary Care Hospital Experience.
CureusAsymptomatic Ileal Intussusception: A Rare Twist in a Marginal B-cell Lymphoma.
Cureus18 F-FDG PET/CT and 68 Ga-Pentixafor PET/CT Findings of Gastric Mucosa-associated Lymphoid Tissue Lymphoma Transformation to Diffuse Large B-cell Lymphoma.
Clinical nuclear medicineEndoscopic features differentiating non-Helicobacter pylori Helicobacter-induced gastric mucosa-associated lymphoid tissue lymphoma with a nodular gastritis-like appearance and H. pylori-induced conventional nodular gastritis.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy SocietyA case of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in a patient with a history of idiopathic lymphocytic interstitial pneumonia (iLIP).
General thoracic and cardiovascular surgery casesA scoping review of worldwide guidelines for diagnosis and treatment of Helicobacter pylori infection.
Systematic reviewsInvestigation of cagA, dupA and babA genes among clinical Helicobacter pylori isolates collected from patients suffering from H. pylori gastric disease using real-time PCR.
Journal of microbiological methodsAcute pancreatitis revealing duodenal papilla MALT lymphoma: a case report and review of the literature.
Future science OA[Clinical Characteristics and Prognosis of Primary Pulmonary Lymphoma].
Zhongguo shi yan xue ye xue za zhi["MALT lymphoma in Sjögren disease: To treat or not to treat?": The pros].
La Revue de medecine interneMetachronous Occurrence of Mucosa-associated Lymphoid Tissue (MALT) Lymphoma in the Esophagus and Tonsillar Diffuse Large B-cell Lymphoma 18 Years After Helicobacter pylori Eradication for Gastric MALT Lymphoma.
Internal medicine (Tokyo, Japan)Clinical characteristics and outcomes of primary orbital lymphoma.
European journal of ophthalmologyDiagnosing pulmonary MALT lymphoma: a case of unilateral cystic lesions.
Future science OA["MALT lymphoma in Sjögren disease: To treat or not to treat?": The cons].
La Revue de medecine internePerformance evaluation of MVision AI Contour+ in gastric MALT lymphoma segmentation.
Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyPrimary Breast Extranodal Marginal Zone Lymphoma: A Case Report and Brief Review of the Literature.
Clinical case reportsRadiotherapy for Large Mucosa-Associated Lymphoid Tissue Lymphoma of the Rectum: A Case Report.
CureusPrimary giant mucosa-associated lymphoid tissue lymphoma of the lower lip: a case report and literature review.
BMC oral healthPrimary Mucosa-Associated Lymphoid Tissue Lymphoma of the Breast with Synchronous Contralateral Invasive Breast Cancer: A Case Report.
Journal of the Korean Society of RadiologyAn unexpected find of multifocal extranodal marginal zone lymphoma.
Annals of hematologyDetection of Helicobacter Pylori in Gastroduodenal Biopsy Samples of Dyspeptic Patients by Rapid Urease Test and Polymerase Chain Reaction in a Tertiary Care Hospital of Bangladesh.
Mymensingh medical journal : MMJ[Update on marginal zone lymphoma classification, diagnosis and treatment in 2024].
Bulletin du cancerCentral Nervous System Manifestations of Cutaneous Lymphomas.
Current neurology and neuroscience reportsGastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance.
Journal of visualized experiments : JoVEComprehensive analysis of imaging and pathological features in 20 cases of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma: a retrospective study.
Journal of thoracic diseaseEpidemiology and Survival of Marginal Zone Lymphoma in Colombian Patients: An Observational Retrospective Study.
JCO global oncologySingle-cell RNA-sequencing reveals cellular heterogeneity and immune microenvironment characteristics between ocular adnexal mucosa-associated lymphoid lymphoma and IgG4-related ophthalmic disease.
Frontiers in immunologyClinical Characteristics and Long-Term Prognosis of Colorectal Mucosa-Associated Lymphoid Tissue Lymphoma According to the Endoscopic Classification and Treatment Modality: A Multicenter Study.
CancersPlasma Cell-Rich Lymphoid Neoplasm in an Endocervical Polyp of the Uterine Cervix in a Perimenopausal 52-Year-Old Woman.
HCA healthcare journal of medicineImmune Cell Crisis and Excess Histopathological Features During the Development and Progression of H. pylori Infection in the Gastric Mucosa.
International journal of general medicineIntraventricular mass in a 52-year-old woman.
Brain pathology (Zurich, Switzerland)A 58-Year-Old Man with a History of Autoimmune Thyroiditis Diagnosed with Mucosa-Associated Lymphoid Tissue Lymphoma and Papillary Carcinoma of the Thyroid.
The American journal of case reportsSOHO State of the Art Updates and Next Questions: Treatment Options for Marginal Zone Lymphoma.
Clinical lymphoma, myeloma & leukemiaDeintensification of radiation dose to 20 Gy for conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma.
Leukemia & lymphomaMucosa-associated lymphoid tissue lymphoma of the dura mimicking meningioma: A case report.
Surgical neurology internationalSimilarities and differences of a proliferation-inducing ligand expression in lacrimal gland lesions of patients with IgG4-associated ophthalmic diseases and mucosa-associated lymphoid tissue lymphoma.
Frontiers in immunologyLong-term cardiac mortality in patients treated with radiation for gastric mucosa-associated lymphoid tissue lymphoma.
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologiqueMALT1 Inhibitors and Degraders: Strategies for NF-κB-Driven Malignancies.
Journal of medicinal chemistryTreatment of primary esophageal lymphomas: A review.
Frontiers in oncologySurgical management of stage IE/IIE primary pulmonary lymphomas: a propensity score matching study.
Journal of thoracic diseaseHelicobacter pylori-positive Colorectal MALT Lymphoma with Repeated Metachronous Recurrence after a Complete Response to Eradication Therapy and Regression after a Watch-and-wait Strategy.
Internal medicine (Tokyo, Japan)Synchronous pancreatic adenocarcinoma and duodenal mucosa‑associated lymphoid tissue lymphoma: A case report.
MedicineNot Every Headache Warrants a Head CT: A Recurrent Headache Unveiling H. Pylori-Positive MALToma.
Case reports in medicine[Research Progress of Pulmonary Extranodal Marginal Zone Lymphoma].
Zhongguo fei ai za zhi = Chinese journal of lung cancerPrimary thyroid mucosa-associated lymphoid tissue marginal zone lymphoma in a 46-year-old female: a case report.
Gland surgeryA Novel Age-Based Nomogram as the Best Predictor for Long-Term Overall Survival in Head and Neck Mucosa-Associated Lymphoid Tissue Lymphoma.
Cancer control : journal of the Moffitt Cancer CenterHypopharyngeal Amyloidosis: A Rare Cause of Dysphagia.
The LaryngoscopeA decade in disguise masquerading as recurrent pneumonia.
The American journal of the medical sciencesAn Occult Primary Thymic Mucosa-Associated Lymphoid Tissue Lymphoma With Sjögren's Syndrome Revealed by CXCR4 Targeted 68Ga-Pentixafor PET/CT.
Journal of cellular and molecular medicineCombined MALT Lymphoma and Early Gastric Cancer in a Reconstructed Gastric Tube Successfully Treated With Endoscopic Submucosal Dissection.
Gastro hep advancesImmunophenotyping of T Cells in Lung Malignancies and Cryptogenic Organizing Pneumonia.
Journal of clinical medicineThe Influence of Gastric Microbiota and Probiotics in Helicobacter pylori Infection and Associated Diseases.
BiomedicinesIncidence trends and prognostic factors in head and neck MALT lymphoma.
Annals of hematologyPrimary Pulmonary MALT Lymphoma on 18 F-FDG and 68 Ga-FAPI PET/CT.
Clinical nuclear medicineClinical analysis of pulmonary mucosa-associated lymphoid tissue lymphoma coexisting with lung cancer.
BMC cancer18F-FDG PET/CT findings in a mucosa-associated lymphoid tissue lymphoma patient coexisting with primary myelofibrosis.
American journal of nuclear medicine and molecular imagingCone Beam Online Adaptive Radiation Therapy: A Promising Approach for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma?
Advances in radiation oncologyAnaemia of Inflammation Preceding Dyspnoea, Dry Cough and Weight Loss in Primary Pulmonary Lymphoma.
European journal of case reports in internal medicine[Primary hepatic diffuse large B-cell lymphoma developed in a patient with primary biliary cholangitis].
[Rinsho ketsueki] The Japanese journal of clinical hematologyMutational Profiling of Korean Lymphomas and Diffuse Large B-Cell Lymphoma Subtype Classification Using Targeted Panel Sequencing.
Archives of medical researchClinical features and temporal trends in H. pylori negative gastric maltoma.
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of GastroenterologyA case of uveoscleral mucosa-associated lymphoid tissue lymphoma with secondary angle-closure glaucoma.
BMC ophthalmologyAberrant bcl6 protein expression in patients with EMZL following recurrence or progression: case report of two cases.
Diagnostic pathology[Characteristics of Gastric Mucosa-associated Lymphoid Tissue Lymphoma in Korea].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chiAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
Ainda não temos associações cadastradas para Linfoma MALT.
É de uma associação que acompanha esta doença? Fale com a gente →
Comunidades
Grupos ativos de quem convive com esta doença aqui no Raras
Ainda não existe comunidade no Raras para Linfoma MALT
Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.
Tire suas dúvidas
Perguntas, dicas e experiências compartilhadas aqui na página
Participe da discussão
Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.
Fazer loginDoenças relacionadas
Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico
Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Which quadruple therapy should be prescribed as first-line treatment for Helicobacter pylori infection? Results of a prospective study comparing concomitant and bismuth therapy.Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology· 2026· PMID 41839716mais citado
- Silent imposter in pneumonic attire: primary pulmonary MALT lymphoma.
- Indolent primary cutaneous B-cell lymphomas resemble persistent antigen reactions without signs of dedifferentiation.
- Esophageal, gastric and duodenal Crohn's disease in the biologic era: Results from a retrospective observational nationwide study of GETECCU.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver· 2026· PMID 41622053mais citado
- Pediatric Orbital MALT Lymphoma Masquerading as a Pyogenic Granuloma.
- Clinicopathological and Imaging Distinction Between Ocular Adnexal MALT Lymphoma and IgG4-Related Ophthalmic Disease.
- Survival outcomes and prognostic nomogram for primary pulmonary MALT lymphoma and diffuse large B-cell lymphoma: A SEER database study.
- [Endoscopic characteristics of primary gastric lymphoma and prediction of treatment response].
- DNA-based characterization of primary hepatic MALT lymphoma reveals a rare FAT3 missense variant and Hippo pathway activation: a case report and literature review.
- Treatment and outcomes of pulmonary mucosa-associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:52417(Orphanet)
- OMIM OMIM:137245(OMIM)
- MONDO:0007650(MONDO)
- GARD:6485(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Q591256(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
