Raras
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Poliarterite nodosa
ORPHA:767CID-10 · M30.0CID-11 · 4A44.4DOENÇA RARA

A poliarterite nodosa (PAN) é uma doença reumatológica rara, com sintomas variados, caracterizada por lesões inflamatórias que destroem o tecido e afetam os vasos sanguíneos pequenos e médios. A PAN afeta mais comumente a pele, as articulações, os nervos periféricos, o intestino e os rins.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

A poliarterite nodosa (PAN) é uma doença reumatológica rara, com sintomas variados, caracterizada por lesões inflamatórias que destroem o tecido e afetam os vasos sanguíneos pequenos e médios. A PAN afeta mais comumente a pele, as articulações, os nervos periféricos, o intestino e os rins.

Pesquisas ativas
6 ensaios
23 total registrados no ClinicalTrials.gov
Publicações científicas
3.539 artigos
Último publicado: 2026 Apr 10

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-9 / 100 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
3.16
Europe
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: M30.0
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧬
Pele e cabelo
3 sintomas
❤️
Coração
3 sintomas
🫃
Digestivo
2 sintomas
🦴
Ossos e articulações
2 sintomas
🧠
Neurológico
2 sintomas
📏
Crescimento
1 sintomas

+ 11 sintomas em outras categorias

Características mais comuns

90%prev.
Morfologia anormal da pele
Muito frequente (99-80%)
55%prev.
Perda de peso
Frequente (79-30%)
55%prev.
Polineurite
Frequente (79-30%)
55%prev.
Febre
Frequente (79-30%)
55%prev.
Concentração elevada de proteína C-reativa circulante
Frequente (79-30%)
55%prev.
Neuropatia periférica
Frequente (79-30%)
28sintomas
Muito frequente (1)
Frequente (10)
Ocasional (14)
Muito raro (3)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 28 características clínicas mais associadas, ordenadas por frequência.

Morfologia anormal da peleAbnormal skin morphology
Muito frequente (99-80%)90%
Perda de pesoWeight loss
Frequente (79-30%)55%
PolineuritePolyneuritis
Frequente (79-30%)55%
FebreFever
Frequente (79-30%)55%
Concentração elevada de proteína C-reativa circulanteElevated circulating C-reactive protein concentration
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico3.539PubMed
Últimos 10 anos200publicações
Pico2025100 papers
Linha do tempo
2026Hoje · 2026🧪 1995Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado1
2Fase 25
·Pré-clínico14
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Poliarterite nodosa

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

6 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

23 ensaios clínicos encontrados, 6 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
956 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 956

#1

Systemic Arterial Aneurysms With Limb Ischemia in a 3-Month-Old Infant: An Unusual Presentation of Incomplete Kawasaki Disease.

Sage open pediatrics2026

Kawasaki disease (KD) is an acute systemic vasculitis predominantly affecting children under 5 years old, characterized by inflammation of medium-sized arteries. The most serious complication is the development of coronary artery aneurysms (CAAs), which can lead to significant cardiovascular morbidity and mortality. Although coronary artery aneurysms (CAAs) are well-documented in KD, the occurrence of systemic arterial aneurysms (SAAs) is rare and less understood. This report describes a 3-month-old male infant with probable/incomplete Kawasaki disease (KD), who presented with bilateral lower limb ischemia due to multiple systemic arterial aneurysms (SAAs) and coronary involvement. Treatment with intravenous immunoglobulin (IVIG) and aspirin led to clinical improvement. This case emphasizes the importance of recognizing incomplete forms of KD and considering differential diagnoses such as infantile polyarteritis nodosa and MIS-C.

#2

Hypertensive crisis due to secondary aldosteronism from polyarteritis nodosa.

BMJ case reports2026 Jan 12

Primary aldosteronism is common in those diagnosed with hypertension and distinguishing primary aldosteronism from its mimics allows tailored management. A woman in her 30s presented to an Australian hospital with hypertensive crisis (209/100 mm Hg) and spontaneous hypokalaemia (2.9 mmol/L). Laboratory tests revealed hyperreninaemic hyperaldosteronism with a normal aldosterone-renin ratio. CT imaging showed focal areas of soft tissue encasement and enhancement surrounding multiple arteries, including the left renal artery, raising suspicion of a medium-vessel vasculitis. Further investigation led to a final diagnosis of polyarteritis nodosa with secondary aldosteronism.

#3

Think Out of the Box-A Rare Case of Intestinal Polyarteritis Nodosa.

The American journal of gastroenterology2026 Jan 01
#4

Systemic Necrotizing Medium-Vessel Vasculitis Clinically Consistent With Polyarteritis Nodosa: A Detailed Case Report.

Cureus2026 Jan

Polyarteritis nodosa (PAN) is a rare necrotizing vasculitis of medium-sized arteries presenting with heterogeneous multisystem involvement. Diagnosis is challenging due to the absence of specific biomarkers, frequent anti-neutrophil cytoplasmic antibodies (ANCA) negativity, variable early imaging findings, and low diagnostic yield of superficial biopsies. We report the case of a 33-year-old man experiencing a four-month evolution of recurrent inflammatory episodes involving abdominal, neurological, cutaneous, and cardiopulmonary systems. He developed dusky necrotizing vasculitic lesions, mononeuritis multiplex-type neuropathy, constitutional symptoms, markedly elevated inflammatory markers, and demonstrated a dramatic response to corticosteroid therapy. Computed tomography angiography was normal, and a superficial punch biopsy performed after steroid initiation was nondiagnostic, reflecting known limitations of sampling depth and timing. Despite this, clinical features, disease trajectory, exclusion of alternative vasculitides, and classical steroid responsiveness strongly supported systemic PAN. This case highlights the diagnostic limitations of biopsy and imaging in early PAN and emphasizes the need for clinical judgment and timely treatment.

#5

Clinical manifestations, prognostic impact, and relapse in polyarteritis nodosa: a systematic review and meta-analysis.

Rheumatology international2026 Feb 19

Polyarteritis Nodosa is a rare necrotizing vasculitis with a broad and variable clinical presentation, driven by its ability to affect multiple organs and systems. This heterogeneity influences disease severity, relapse risk, and mortality, highlighting the prognostic importance of its diverse manifestations. This systematic review and meta-analysis synthesize the available evidence to define the clinical profile of Polyarteritis Nodosa and highlight key prognostic factors. A systematic search of electronic databases was conducted to identify studies reporting clinical manifestations and outcomes of patients diagnosed with Polyarteritis Nodosa. Pooled prevalence summary estimates were calculated using R software, including subgroup analyses by age group. Case Fatality Rate was calculated to determine the clinical severity of the manifestations. Across adult and pediatric groups, the most common manifestations were fever (~ 52%), myalgia (~ 53%), and cutaneous involvement (~ 56%). Age significantly moderated the prevalence of fever, arthralgia, hypertension, and peripheral neuropathy. Several symptoms were frequently observed among patients who experienced relapse, particularly cutaneous involvement (~ 66%) and myalgia (~ 64%). While cardiac involvement was associated with higher case fatality, gastrointestinal manifestations accounted for a greater proportion of reported deaths overall. Total mortality was approximately 13%, relapse occurred in about 27% of patients, while roughly 65% of patients achieved remission. This systematic review with meta-analysis provides crucial information to clinical physicians, regarding the clinical profile and the prognostic factors of Polyarteritis Nodosa. Thus, these insights could guide management strategies and increase the survival and remission rate of these patients. PROSPERO: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251249274. The online version contains supplementary material available at 10.1007/s00296-026-06082-8.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC2.134 artigos no totalmostrando 195

2026

Myeloperoxidase anti-neutrophil cytoplasmic antibody vasculitis mimicking renal polyarteritis nodosa.

Journal of nephrology
2025

[Polyarteritis nodosa: an etiology of myelitis that should not be ignored in subsaharansub-Saharan Africa].

Medecine tropicale et sante internationale
2026

Systemic Necrotizing Medium-Vessel Vasculitis Clinically Consistent With Polyarteritis Nodosa: A Detailed Case Report.

Cureus
2026

Clinical manifestations, prognostic impact, and relapse in polyarteritis nodosa: a systematic review and meta-analysis.

Rheumatology international
2026

Drug-induced renal function deterioration in a patient with polyarteritis nodosa.

Farmaceuticos comunitarios
2026

Systemic Arterial Aneurysms With Limb Ischemia in a 3-Month-Old Infant: An Unusual Presentation of Incomplete Kawasaki Disease.

Sage open pediatrics
2026

Maternal and perinatal outcomes in vasculitis: a 15-year study at a Portuguese tertiary multidisciplinary centre.

Rheumatology advances in practice
2026

Therapeutic management of inflammatory heart diseases.

Pharmacology &amp; therapeutics
2026

Navigating clinical overlap: A case of polyarteritis nodosa in the setting of antiphospholipid syndrome.

Modern rheumatology case reports
2026

Successful treatment of aneurysmal subarachnoid hemorrhage in polyarteritis nodosa with immunosuppressive therapy: illustrative case.

Journal of neurosurgery. Case lessons
2026

Polyarteritis nodosa with isolated organ involvement requiring resection in the genitourinary system.

Annals of diagnostic pathology
2026

Hypertensive crisis due to secondary aldosteronism from polyarteritis nodosa.

BMJ case reports
2026

Bilateral spontaneous kidney rupture in a patient with polyarteritis nodosa disguising as granulomatosis with polyangiitis.

Polish archives of internal medicine
2025

Localized Immune-Complex Small-Vessel Vasculitis Presenting as Unilateral Myositis After Hepatitis A.

Cureus
2025

Fever of unknown origin, muscle weakness, and an adrenal nodule-the cat we chased like a hare: a case report.

Journal of medical case reports
2025

Vasculitic fasciitis characterizes a distinct subset of vasculitic myopathy with interferon-gamma signature.

Acta neuropathologica
2025

MRI-guided muscle biopsy improves diagnostic yield in small- to medium-vessel vasculitis: a retrospective single-center study.

Rheumatology international
2025

Clinical Implications of Vasculitis Associated with Familial Mediterranean Fever: A Comparative Study in Childhood.

Modern rheumatology
2026

Polyarteritis nodosa associated with VEXAS syndrome and chronic myelomonocytic leukemia: a case-control study.

Rheumatology (Oxford, England)
2025

A Case of Challenging Polyarteritis Nodosa With Critical Limb Ischemia.

Cureus
2025

Polyarteritis Nodosa With Mesenteric, Hepatic, and Musculoskeletal Manifestations in a 36-Year-Old Nigerian Male Patient: A Case Report.

Cureus
2025

Polyarteritis nodosa with abdominal pain as the main symptoms: A case report.

Medicine
2026

Tocilizumab for refractory and/or relapsing polyarteritis nodosa.

Journal of the American Academy of Dermatology
2026

Clinical and laboratory predictors of diagnostic delay in childhood Takayasu arteritis and PAN: a retrospective cohort study.

Rheumatology (Oxford, England)
2025

Adenosine deaminase 2 (ADA2) deficiency masquerading as polyarteritis nodosa.

JAAD case reports
2025

Nonspecific Interstitial Pneumonia Pattern as an Atypical Pulmonary Manifestation of Polyarteritis Nodosa.

Cureus
2025

Canine Cardiac and Cardiovascular Pathology: Four Major Life-Threatening Non-Degenerative, Non-Hereditary Conditions.

Veterinary sciences
2025

Clinical Spectrum and One-Year Outcomes of Central Nervous System Vasculitis Secondary to Systemic Autoimmune Disorders: A Retrospective Cohort Study.

Cureus
2025

Severe relapse of cutaneous polyarteritis nodosa triggered by bacterial cellulitis.

European journal of dermatology : EJD
2026

Diagnostic yield of biopsy in cutaneous polyarteritis nodosa: A retrospective cohort study from 2 academic centers.

Journal of the American Academy of Dermatology
2025

Diverse Phenotypic Expressions of ADA2 Deficiency: Two Case Studies.

Iranian journal of allergy, asthma, and immunology
2026

Polyarteritis nodosa presenting with TAFRO signs following COVID-19 infection: case report.

Modern rheumatology case reports
2026

A visual guide for emergency radiologists navigating the complexity of abdominal vasculitis: part 1 - true vasculitis.

Emergency radiology
2025

Tumor Necrosis Factor Inhibitor Therapy in Polyarteritis Nodosa: Expanding Evidence From Systemic to Cutaneous Disease.

The Journal of rheumatology
2025

Role of F-18 FDG-PET CT scan in the evaluation of medium vessel vasculitis.

Seminars in arthritis and rheumatism
2026

Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants.

Arthritis &amp; rheumatology (Hoboken, N.J.)
2025

Nodular Polyarteritis With Superior Mesenteric Artery Involvement: A Report of a Complex Case.

British journal of hospital medicine (London, England : 2005)
2025

Coronary Arteritis in Polyarteritis Nodosa.

QJM : monthly journal of the Association of Physicians
2025

Polyarteritis nodosa presenting with pancreatic-artery rupture and co-existing MEFV and ADA2 mutation: clinicopathological and genomic insights from a case report.

Virchows Archiv : an international journal of pathology
2025

Efficacy and safety of tocilizumab in polyarteritis nodosa and adenosine deaminase 2 deficiency: a systematic literature review.

Clinical and experimental rheumatology
2025

Polyarteritis nodosa: a tale of two atypical presentations.

BMJ case reports
2025

New avenues in childhood vasculitis.

Pediatric rheumatology online journal
2026

Cotton-Wool Appearance of Muscular Polyarteritis Nodosa on Contrast Magnetic Resonance Imaging.

The Journal of rheumatology
2026

Muscular polyarteritis nodosa.

Internal and emergency medicine
2025

The Case | A patient with malignant hypertension, thrombotic microangiopathy, and perinephric hematoma after a biopsy.

Kidney international
2025

Polyarteritis nodosa with cutaneous manifestations localized to the upper limb, possibly caused by trauma.

European journal of dermatology : EJD
2025

Successful Treatment of Polyarteritis Nodosa With Multifocal Intracranial and Mesenteric Stenoses Using Endovascular Stenting and Tocilizumab.

Cureus
2025

A Clinical Case Report of Deficiency of Adenosine Deaminase 2 Syndrome (DADA 2) Presenting as a Brachial Artery Aneurysm.

Mediterranean journal of rheumatology
2025

Polyarteritis Nodosa with Concurrent CMV Infection: A Case Report and Brief Literature Review.

South Dakota medicine : the journal of the South Dakota State Medical Association
2025

Vasculitis as an indicator of disease severity in familial Mediterranean fever.

Frontiers in immunology
2025

Cardiac disease in patients with vasculitis.

Clinical research in cardiology : official journal of the German Cardiac Society
2025

Clinical value of biomarkers in relation to artery size in eosinophilic granulomatosis with polyangiitis: findings from an inception cohort at a Japanese City Hospital.

Clinical rheumatology
2025

Pediatric-Onset Polyarteritis Nodosa and Deficiency of Adenosine Deaminase 2: Clinical Overlap and Divergence.

Journal of clinical rheumatology : practical reports on rheumatic &amp; musculoskeletal diseases
2025

Cognitive impairment and other neuropsychiatric manifestations in patients with primary vasculitis: a systematic review.

Seminars in arthritis and rheumatism
2025

Reticulated violaceous patches in a 10-year-old boy.

JAAD case reports
2025

C4d Immunoreactivity in Autoimmune and HBV-Induced Hepatitis: Implications for Complement-Mediated Hepatocellular Injury.

Pathophysiology : the official journal of the International Society for Pathophysiology
2025

Diagnosis and outcomes of fever of unknown origin cases with an erythrocyte sedimentation rate of 100 mm/h or more: An International ID-IRI (Infectious Diseases - International Research Initiative) Observational Retrospective Cohort Study.

Medicine
2025

Coronary Polyarteritis Nodosa: Clinical Dilemmas in Diagnosis and Management.

JACC. Case reports
2025

Temporal arteritis and vasculitic myopathy in polyarteritis nodosa.

Journal of neurology
2025

Polyarteritis nodosa with testicular involvement: a rare case report highlighting the role of nuclear imaging and angiography in diagnosis.

BJR case reports
2025

Teaching NeuroImage: Vasculitic Neuropathy With Cutaneous Polyarteritis Nodosa.

Neurology
2025

[Abnormal renal arteriography].

La Revue de medecine interne
2025

Muscular polyarteritis nodosa: a diagnostic and therapeutic challenge.

BMJ case reports
2025

NET Proteomic Profiling Reveals New Pathways Potentially Implicated in Dendritic Cell-Mediated Inflammation in DADA2 Patients.

Journal of clinical immunology
2025

Reversible Cardiomyopathy in Polyarteritis Nodosa: A Case Report.

Cureus
2025

Cutaneous Polyarteritis Nodosa-Like Vasculitis Possibly Induced by Osimertinib.

International journal of dermatology
2025

Spontaneous accessory renal artery aneurysm rupture as a first presentation of polyarteritis nodosa: a case report and review of literature.

Annals of medicine and surgery (2012)
2025

Effective Pain Management in Polyarteritis Nodosa (PAN) Utilizing Lumbar Sympathetic Blocks: A Case Report.

Anesthesiology and pain medicine
2025

Successful treatment with tocilizumab in a case of familial Mediterranean fever with Takayasu arteritis.

Modern rheumatology case reports
2025

Vasculitis in an Infant Born to a Mother With Longstanding Cutaneous Polyarteritis Nodosa: A Case Report and Review of Literature.

Pediatric dermatology
2025

Beyond Ulcerations: A Case of Cutaneous Polyarteritis Nodosa in a Middle-Aged Woman.

Cureus
2026

Think Out of the Box-A Rare Case of Intestinal Polyarteritis Nodosa.

The American journal of gastroenterology
2025

Efficacy of Tumor Necrosis Factor Inhibitors for Refractory Leg Ulcers in Cutaneous Polyarteritis Nodosa: A Case Series.

The Journal of rheumatology
2025

F18-FDG PET-CT Findings in Juvenile-Onset Polyarteritis Nodosa: A First Series and Literature Review.

Journal of clinical medicine
2025

Direct immunofluorescence testing for panniculitis offers negligible diagnostic utility: A retrospective single-center cohort study of 87 specimens.

Journal of the American Academy of Dermatology
2025

IgA vasculitis associated with chronic myelomonocytic leukemia.

BMC rheumatology
2025

Minocycline-induced Polyarteritis Nodosa Manifesting as Tenosynovitis, Edema, and Rash: A Case Report.

The Israel Medical Association journal : IMAJ
2025

Case Report: A case of cutaneous polyarteritis nodosa in a child following a streptococcal infection.

Frontiers in pediatrics
2025

Supplementation with Pycnogenol® relieves symptoms of chronic inflammatory diseases with a significant vasculitis component: a pilot registry study.

Minerva medica
2025

Complex presentation of polyarteritis nodosa: Renal pseudoaneurysm rupture and bowel ischemia: A case report.

International journal of surgery case reports
2025

Mimics and challenging presentations of DADA2.

Clinical and experimental immunology
2025

Artificial intelligence challenge of discriminating cutaneous arteritis and polyarteritis nodosa based on hematoxylin-and-eosin images of skin biopsy specimens.

Pathology, research and practice
2025

Cutaneous Arteritis Complicated by Crohn's Disease.

Internal medicine (Tokyo, Japan)
2025

Idiopathic polyarteritis nodosa - does it still exist? Viewpoint 1: as our knowledge makes progress, idiopathic polyarteritis nodosa is fading away.

Rheumatology (Oxford, England)
2025

Idiopathic polyarteritis nodosa-does it still exist? Viewpoint 2: idiopathic polyarteritis nodosa is rare, but still exists.

Rheumatology (Oxford, England)
2025

Clinical characterization of aortitis and periaortitis: study of 134 patients from a single university hospital.

Internal and emergency medicine
2025

Efficacy of Upadacitinib in refractory Polyarteritis Nodosa: a case report.

Oxford medical case reports
2025

Fasciitis-panniculitis syndrome with autoantibodies reacting to adipocyte pericellular fibers: a case report.

Pediatric rheumatology online journal
2025

Identifcation of candidate biomarkers for polyarteritis nodosa using data-independent acquisition mass spectrometry.

American journal of translational research
2025

Polyarteritis nodosa initially presenting as ocular motility impairment and diplopia with subsequent development of bilateral central retinal artery occlusion: A case report.

American journal of ophthalmology case reports
2024

Effect of trace elements and nutrients on 21 autoimmune diseases: a Mendelian randomization study.

Frontiers in immunology
2025

A Rare Case of Goodpasture's Syndrome Combined with Polyarteritis Nodosa.

Internal medicine (Tokyo, Japan)
2025

Incidence of ANCA-associated vasculitis and polyarteritis nodosa in Norfolk, UK, from 2011 to 2020.

Rheumatology (Oxford, England)
2025

Radiological insights into fibromuscular dysplasia unveiled by intracranial aneurysms and iliac vein hypoplasia in suspected DVT.

Radiology case reports
2025

Analysis of macular retinal thickness in polyarteritis nodosa using spectral domain optical coherence tomography.

Journal of ophthalmic inflammation and infection
2024

Polyarteritis nodosa with life-threatening intracranial aneurysms in a child, and treatment with infliximab.

The Turkish journal of pediatrics
2025

The clinical characteristics and treatment outcomes of patients with systemic polyarteritis nodosa: a single-centre study from India.

Rheumatology (Oxford, England)
2025

Coronary polyarteritis nodosa in a young adult - Authors' reply.

The Lancet. Rheumatology
2025

Coronary polyarteritis nodosa in a young adult.

The Lancet. Rheumatology
2025

A case of renovascular hypertension due to polyarteritis nodosa.

Journal of hypertension
2025

Rapidly progressive digital necrosis in polyarteritis nodosa.

Rheumatology advances in practice
2025

Extreme Phenotypic Variation in Siblings with Identical Homozygous Mutations Causing ADA2 Deficiency: A Case Series.

Turkish journal of haematology : official journal of Turkish Society of Haematology
2025

Lethal Gastrointestinal Manifestation and 3D-Reconstructive CT in Systemic Polyarteritis Nodosa (PAN).

International journal of rheumatic diseases
2024

Polyangiitis Overlap Syndrome: Polyarteritis Nodosa with Leukocytoclastic Vasculitis Associated with Left Ventricular Thrombus and Vocal Cord Palsy: A Case Report.

Oman medical journal
2025

Effectiveness of the combined therapy in the treatment of chronic non-healing wounds in patients with autoimmune diseases.

Journal of plastic, reconstructive &amp; aesthetic surgery : JPRAS
2024

Polyarteritis nodosa presenting with severe upper gastrointestinal bleeding: a case report.

Journal of medical case reports
2025

A case of polyarteritis nodosa with severe lower limb ulcer that was treated with prednisolone and tocilizumab.

Modern rheumatology case reports
2025

An autopsy of a patient with polyarteritis nodosa who developed fatal intestinal perforation accompanied by systemic multiple aneurysms and arterial thrombosis.

Modern rheumatology case reports
2025

Comparison of [18F]FAPI-42 and [18F]FDG PET/CT in the evaluation of systemic vasculitis.

European journal of nuclear medicine and molecular imaging
2024

Misdiagnosed for 14 Years: Adenosine Deaminase 2 (ADA2) Deficiency in a Teen Mimicking Polyarteritis Nodosa.

Clinical case reports
2025

Coronary polyarteritis nodosa.

The Lancet. Rheumatology
2025

Mechanisms and Screening for Atherosclerosis in Adults With Vasculitis.

Arteriosclerosis, thrombosis, and vascular biology
2025

Angiographic imaging of the testicular arteries with polyarteritis nodosa: A case report.

Radiology case reports
2024

Long-term follow-up of anti-TNF treatment in adult and pediatric DADA2 patients: Insights from real-world data.

International journal of rheumatic diseases
2025

Renovascular hypertension - a primer for the radiologist.

Abdominal radiology (New York)
2024

Hospitalist-performed skin biopsy in the diagnosis of skin disease.

Archives of dermatological research
2024

Deficiency of adenosine deaminase 2 (DADA2) presented with bilateral renal subcapsular hematoma: a case report and literature review.

Annals of medicine and surgery (2012)
2024

Successful treatment of cutaneous polyarteritis nodosa with baricitinib.

The Journal of dermatological treatment
2024

Resilience and Beyond the Acute Phase Challenges: Case Series on Prolonged COVID-19 Infection in Immunocompromised Individuals.

Infection and drug resistance
2024

18 F-FDG PET/CT in the Evaluation of Polyarteritis Nodosa.

Clinical nuclear medicine
2025

French protocol for diagnosis and management of Cogan's syndrome.

La Revue de medecine interne
2025

Page kidney in a case of polyarteritis nodosa.

Forensic science, medicine, and pathology
2024

Polyarteritis nodosa mimics Kawasaki disease.

BMJ case reports
2024

Uncommon triple vessel spontaneous coronary artery dissection in the setting of polyarteritis nodosa: a case report.

Journal of medical case reports
2025

Sudden cardiac death caused by Kawasaki coronary artery vasculitis in a child with Hodgkin's lymphoma. Case report and literature review.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
2025

Critical Limb Threatening Ischemia Due to Severe Polyarteritis Nodosa.

Internal medicine (Tokyo, Japan)
2025

Immunosuppression Therapy for Chronic Limb-threatening Ischemia in a Patient with Severe Polyarteritis Nodosa.

Internal medicine (Tokyo, Japan)
2025

Clinical Outcomes After Distal Bypass in Patients With Chronic Limb-Threatening Ischemia due to Connective Tissue Disease.

Vascular and endovascular surgery
2025

Top 10 Clinical Pearls in Vasculitic Neuropathies.

Seminars in neurology
2025

Constitutional symptoms of severe childhood-onset polyarteritis nodosa.

The Lancet. Rheumatology
2024

Diagnostic Value of Whole-Body MRI in Pediatric Patients with Suspected Rheumatic Diseases.

Medicina (Kaunas, Lithuania)
2025

[Vasculitic involvement of the skeletal muscle and the peripheral nervous system: clinical and neuropathologic perspective].

Zeitschrift fur Rheumatologie
2024

Rheumatoid Vasculitis Involving Gastrointestinal Tract Pre-dating Rheumatoid Arthritis: A Case Study and Literature Review.

Cureus
2024

Muscular polyarteritis nodosa detected by FDG-PET/CT.

International journal of rheumatic diseases
2025

Clinical spectrum of and outcomes for Indian children with deficiency of adenosine deaminase 2 (DADA2): a multicentric study.

Rheumatology (Oxford, England)
2025

The coincidence of multiple sclerosis and primary vasculitis; from the bench of pathology to the bedside of treatment: a systematic review of case reports.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2024

Polyarteritis nodosa complicated by renal aneurysm and intestinal perforation: A case report.

Medicine
2024

Case report: Cutaneous polyarteritis nodosa presenting with ulcers in atypical localizations and atypical skin rashes: A report of a rare case.

International journal of rheumatic diseases
2024

Early skeletal muscle manifestations in polyarteritis nodosa and ANCA-associated vasculitis.

Autoimmunity reviews
2024

Polyarteritis nodosa with abdominal bleeding: imaging with PET/CT and angiography on the same day.

Rheumatology advances in practice
2025

Possible usefulness of fluorodeoxyglucose positron emission tomography in diagnosing polyarteritis nodosa: A case report and literature review.

Modern rheumatology case reports
2024

Adalimumab-induced leukocytoclastic vasculitis in a patient with ankylosing spondylitis: A case report.

Clinical case reports
2024

[Allogeneic haematopoietic stem cell transplantation induced remission of periarteritis nodosa associated with azacytidine-refractory myelodysplastic syndrome].

La Revue de medecine interne
2024

Muscular polyarteritis nodosa with fasciitis and upper extremity involvement.

Rheumatology advances in practice
2024

Kidney involvement in myelodysplastic syndromes.

Clinical kidney journal
2024

Autoimmune inner ear disease associated with antiphospholipid antibodies.

Clinical and experimental rheumatology
2024

COVID-19 associated cutaneous polyarteritis nodosa.

The American journal of the medical sciences
2024

A great simulator in clinical practice: mononeuritis multiplex in HIV infection.

Autopsy &amp; case reports
2024

Autoimmunity in patients with inborn errors of immunity: A case series.

Reumatologia clinica
2024

Spontaneous hepatic artery pseudoaneurysm rupture as a first presentation of polyarteritis nodosa.

BMJ case reports
2024

Ulcerative colitis: a diagnostic odyssey through cutaneous polyarteritis nodosa and granulomatous hepatitis.

BMJ case reports
2024

Histopathological Confirmation of Axonal Sprouting in Regenerative Peripheral Nerve Interface.

Plastic and reconstructive surgery. Global open
2024

Apremilast successfully treats cutaneous polyarteritis nodosa associated with SAPHO syndrome.

Rheumatology (Oxford, England)
2024

Case report of streptococcal infection as a potential precipitating factor in cutaneous polyarteritis nodosa in pediatric patients.

Clinical case reports
2024

Severe infections in systemic necrotizing vasculitis.

Reumatologia clinica
2024

Kidney rupture in a patient with polyarteritis nodosa.

Polish archives of internal medicine
2024

Rapidly Progressive, Symmetrical, Acute Cutaneous Necrosis of Bilateral Lower Limbs: A Rare Presentation of Polyarteritis Nodosa.

Cureus
2024

Deficiency of adenosine deaminase 2: a genetic autoinflammatory disorder mimicking childhood polyarteritis nodosa.

BMJ case reports
2024

Clinical and laboratory findings characterizing the need for systemic corticosteroids and nonsteroidal systemic therapies and the predicted outcomes in cutaneous polyarteritis nodosa: a single-centre retrospective analysis.

Clinical and experimental dermatology
2024

Ophthalmic vascular manifestations in eosinophil-associated diseases: a comprehensive analysis of 57 patients from the CEREO and EESG networks and a literature review.

Frontiers in immunology
2024

Eosinophilic granulomatosis with polyangiitis and its association with montelukast: a case-based review.

Clinical rheumatology
2024

Gastroduodenal artery aneurysm - an extremely rare but insidious cause of abdominal pain: a case report.

The Pan African medical journal
2024

Multi-Modality Imaging in Vasculitis.

Diagnostics (Basel, Switzerland)
2024

Coinciding Crohn's disease and polyarteritis nodosa: A sign of medically refractory disease?

International journal of rheumatic diseases
2024

Visualization of intradermal blood vessel structures by dual-wavelength photoacoustic microscopy and characterization of three-dimensional construction of livedo-racemosa in cutaneous polyarteritis nodosa.

Journal of dermatological science
2024

Anti-LAMP-2 Antibody Seropositivity in Children with Primary Systemic Vasculitis Affecting Medium- and Large-Sized Vessels.

International journal of molecular sciences
2024

Cutaneous polyarteritis nodosa: it is not always erythema nodosum.

Anales de pediatria
2024

Neuro-ophthalmic challenges and multi-morbidity in vasculitis among the older adults.

Expert review of clinical immunology
2024

Shifting perspectives in coronary involvement of polyarteritis nodosa: case of 3-vessel occlusion treated with 4-vessel CABG and review of literature.

BMC cardiovascular disorders
2024

A Rare Presentation of Polyarteritis Nodosa (PAN).

Cureus
2024

The Extinction of Primary Polyarteritis Nodosa: A Modern Science Success Story?

Arthritis &amp; rheumatology (Hoboken, N.J.)
2024

Wunderlich syndrome as a rare complication of polyarteritis nodosa: a case report.

Reumatismo
2024

Comparison of characteristics of muscle magnetic resonance imaging findings in patients with antineutrophilic cytoplasmic antibody-associated vasculitis and polyarteritis nodosa.

International journal of rheumatic diseases
2024

Post COVID-19 vaccination medium vessel vasculitis: a systematic review of case reports.

Infection
2024

Stroke frequency, associated factors, and clinical features in primary systemic vasculitis: a multicentric observational study.

Journal of neurology
2024

APDS patients with immune-complex vasculitis and resolution with leniolisib.

Clinical immunology (Orlando, Fla.)
2024

Polyarteritis nodosa with superior mesenteric artery dissection.

The American journal of the medical sciences
2024

Polyarteritis nodosa with splenic rupture and multiple cerebral infarctions.

The Journal of dermatology
2024

New-onset autoimmune disease after COVID-19.

Frontiers in immunology
2024

Images in Vascular Medicine: The large PANeurysm - A rare case of hepatic artery aneurysm in a 25-year-old woman with polyarteritis nodosa.

Vascular medicine (London, England)
2024

Clinical Characteristics and Outcomes of Polyarteritis Nodosa: An International Study.

Arthritis &amp; rheumatology (Hoboken, N.J.)
2024

Nationwide epidemiological survey of polyarteritis nodosa in Japan in 2020.

Modern rheumatology
2024

Von Willebrand factor: a possible biomarker for disease activity in vasculitis.

Scandinavian journal of rheumatology
2024

Ruptured Saccular Aneurysm Caused by Necrotizing Arteritis of the Polyarteritis Nodosa Type in Primary Angiitis of Central Nervous System.

International journal of surgical pathology
2024

[Immunoglobulin A vasculitis].

Innere Medizin (Heidelberg, Germany)
2024

Vasculitis-panniculitis mimicking unresolved diabetic foot ulcer.

Endocrinology, diabetes &amp; metabolism case reports
2024

Left main and three vessels spontaneous coronary artery dissection as an incidental finding in young man with history of Hodgkin's lymphoma-a case report.

BMC cardiovascular disorders
2024

[Polyarteritis nodosa and Kawasaki syndrome : Vasculitis predominantly of medium size and small vessels].

Innere Medizin (Heidelberg, Germany)
2024

VEXAS syndrome: Clinical manifestations, diagnosis, and treatment.

Reumatologia clinica
2023

Spontaneous Hepatic Rupture in the Setting of Peliosis Hepatis and End-Stage Renal Disease.

Cureus
2024

Relapsing Hepatitis B-associated Vasculitis with Features of Polyarteritis Nodosa and c-Antineutrophilic Cytoplasmic Antibodies-associated Vasculitis.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
2023

[Vasculitis as a cause of stroke].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2024

Comparison of EULAR/PRINTO/PReS Ankara 2008 and 2022 ACR/EULAR classification criteria for granulomatosis with polyangiitis in children.

Rheumatology (Oxford, England)
2024

Clinical characteristics, disease trajectories and management of vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome: a systematic review.

Rheumatology international
2023

Cutaneous polyarteritis nodosa and pulmonary arterial hypertension: An unexpected liaison. A case report.

Medicine
Ver todos os 2.134 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Systemic Arterial Aneurysms With Limb Ischemia in a 3-Month-Old Infant: An Unusual Presentation of Incomplete Kawasaki Disease.
    Sage open pediatrics· 2026· PMID 41684753mais citado
  2. Hypertensive crisis due to secondary aldosteronism from polyarteritis nodosa.
    BMJ case reports· 2026· PMID 41526073mais citado
  3. Think Out of the Box-A Rare Case of Intestinal Polyarteritis Nodosa.
    The American journal of gastroenterology· 2026· PMID 40392242mais citado
  4. Systemic Necrotizing Medium-Vessel Vasculitis Clinically Consistent With Polyarteritis Nodosa: A Detailed Case Report.
    Cureus· 2026· PMID 41737102mais citado
  5. Clinical manifestations, prognostic impact, and relapse in polyarteritis nodosa: a systematic review and meta-analysis.
    Rheumatology international· 2026· PMID 41711936mais citado
  6. [(18)F]FDG PET/CT value in the diagnostic evaluation of patients with polyarteritis nodosa.
    Eur J Nucl Med Mol Imaging· 2026· PMID 41957293recente
  7. Catastrophic Brain Hemorrhage in a Teenager With Immune Thrombocytopenia and Polyarteritis Nodosa.
    Pediatr Blood Cancer· 2026· PMID 41943533recente
  8. Paraneoplastic necrotizing medium-vessel vasculitis mimicking polyarteritis nodosa with large-vessel involvement.
    Clin Rheumatol· 2026· PMID 41896499recente
  9. Myeloperoxidase anti-neutrophil cytoplasmic antibody vasculitis mimicking renal polyarteritis nodosa.
    J Nephrol· 2026· PMID 41774610recente
  10. [Polyarteritis nodosa: an etiology of myelitis that should not be ignored in subsaharansub-Saharan Africa].
    Med Trop Sante Int· 2025· PMID 41768948recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:767(Orphanet)
  2. MONDO:0019170(MONDO)
  3. GARD:7360(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q745162(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Poliarterite nodosa
Compêndio · Raras BR

Poliarterite nodosa

ORPHA:767 · MONDO:0019170
Prevalência
1-9 / 100 000
Herança
Not applicable
CID-10
M30.0 · Poliarterite nodosa
CID-11
Ensaios
6 ativos
Início
All ages
Prevalência
3.16 (Europe)
MedGen
UMLS
C0031036
EuropePMC
Wikidata
Wikipedia
Papers 10a
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