Recurrent pyoderma gangrenosum-like ulcers in a child revealing leukocyte adhesion deficiency type I.

Integrin activation by two independently regulated calcium-mediated pathways is required for neutrophil recruitment.

L-fucose supplementation in a patient with global hypofucosylation and a mono-allelic variant in SLC35C1: Clinical improvement and assessment of biomarkers.

Genetic Determinants of Wound Healing: Monogenic Disorders and Polygenic Influence.

Differences in Inflammatory Genetic Profiles in Periodontitis Associated with Genetic and Immunological Disorders: A Systematic Review.

Bone marrow transplantation for leukocyte adhesion deficiency type III: immunosuppressant dosage adjustments against severe T-cell mixed chimerism.

What should be investigated in delayed umbilical cord separation: Two case reports.

''Clinical Management of Acute Mastoiditis in a Pediatric Patient with Leukocyte Adhesion Deficiency''.

Periodontal Manifestations of Systemic Diseases.

Hematopoietic cell transplantation for leukocyte adhesion deficiency: prevention of graft-versus-host-disease.

Successful management of a pediatric cardiac patient with Bombay blood group and leukocyte adhesion deficiency type II: A case report and literature review.

An atypical adolescent case of leukocyte adhesion deficiency I caused by a novel ITGB2 splicing variant with successful immune reconstitution following hematopoietic stem cell transplantation.

Hydrophobicity-Driven Disruption Mechanism in Kindlin-3 Induced by Leukocyte Adhesion Deficiency Mutation.

Lentiviral Gene Therapy for Severe Leukocyte Adhesion Deficiency Type 1.

Leukocyte adhesion deficiency type III in an infant presenting with intestinal perforation and low percentage of natural killer cells: first case report from Iran.

A novel ITGB2 variant in a patient with severe recurrent pyoderma gangrenosum-like lesions and underlying leukocyte adhesion deficiency type I: case report and literature review.

Lymphoblastoid and Jurkat cell lines are useful surrogate in developing a CRISPR-Cas9 method to correct leukocyte adhesion deficiency genomic defect.

A Novel Variant of the FERMT3 Gene Associated With Leukocyte Adhesion Deficiency Type III (LAD-III) in a Saudi Family: A Case Series.

Gene therapy for inborn errors of immunity: Current clinical progress.

Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report.

Viral-based gene therapy clinical trials for immune deficiencies and blood disorders from 2013 until 2023 - an overview.

Distribution of Recessive Genetic Defect Carriers in Holstein Friesian Cattle: A Polish Perspective.

Eight induced pluripotent stem cell lines (iPSCs) derived from two patients with Leukocyte adhesion deficiency Type I (LAD I) with mutations in the ITGB2 gene.

Sequence variants underlying severe combined immunodeficiency and leukocyte adhesion deficiency type 1 in six consanguineous families.

Unveiling genetic variants: Tetra-primer ARMS-PCR diagnosis and structural insights into BLAD, BC, and DUMPS in Pakistani cattle herds.

Selected Monogenic Genetic Diseases in Holstein Cattle-A Review.

Sweet syndrome associated with moderate leukocyte adhesion deficiency type I: a case report and review of the literature.

The sufficiency of genetic diagnosis in managing patients with inborn errors of immunity during prenatal care and childbearing.

Mutations in the SLC35C1 gene, contributing to significant differences in fucosylation patterns, may underlie the diverse phenotypic manifestations observed in leukocyte adhesion deficiency type II patients.

Multiplex fluorescent amplification-refractory mutation system PCR method for the detection of 10 genetic defects in Holstein cattle and its comparison with the KASP genotyping assay.

Analysis of Clinical, Immunological and Molecular Features of Leukocyte Adhesion Deficiency Type I in Egyptian Children.

Ustekinumab for pyoderma gangrenosum-like skin ulcerations in late-onset leukocyte adhesion deficiency.

Integrins in Health and Disease-Suitable Targets for Treatment?

LAD-III, a Mild Phenotype Resulting From a Novel Variant of FERMT3 Gene: A Case Report.

Clinical and functional spectrum of RAC2-related immunodeficiency.

Extensive perineal ecthyma gangrenosum in leukocyte adhesion deficiency type 1 associated with Staphylococcus hominis bacteremia.

Role of genetic introgression in introducing mutant alleles in Bos indicus cattle and prevalence of lethal genetic disorders in Bos taurus × Bos indicus and Bos indicus cattle in India.

Clinical manifestations and expression of CD18 to guide the diagnosis of leukocyte adhesion deficiency type 1: Mexico experience.

A novel leukocyte adhesion deficiency type III mutation manifests functional importance of the compact FERM domain in kindlin-3.

Who's your data? Primary immune deficiency differential diagnosis prediction via machine learning and data mining of the USIDNET registry.

Variable CD18 expression in a 22-year-old female with leukocyte adhesion deficiency I: Clinical case and literature review.

The impact of Treosulfan-based conditioning for inborn errors of immunity: Is dose monitoring crucial?

Clinical and immunological characteristics of 69 leukocyte adhesion deficiency-I patients.

Defective Treg generation and increased type 3 immune response in leukocyte adhesion deficiency 1.

Improved Outcome Following Busulfan-Based Conditioning in Children with Functional Neutrophil Disorders Undergoing Hematopoietic Stem Cell Transplant from HLA-Matched Donors.

The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells-Lessons Learned from Different Transgenic Mouse Models.

Clinical and Osteopetrosis-Like Radiological Findings in Patients with Leukocyte Adhesion Deficiency Type III.

Pediatric pyoderma gangrenosum associated with leukocyte adhesion deficiency type 1: A case report and review of the literature.

[Leucocyte adhesion deficiency: detection of the first cases in Paraguay].

Hematologically important mutations: Leukocyte adhesion deficiency (second update).

A Novel Deletion in FERMT3 Causes LAD-III in a Turkish Family.

Phosphorylation Regulation Mechanism of β2 Integrin for the Binding of Filamin Revealed by Markov State Model.

Case report: HLA-haploidentical hematopoietic cell transplant with posttransplant cyclophosphamide in a patient with leukocyte adhesion deficiency type I.

Impaired Treg-DC interactions contribute to autoimmunity in leukocyte adhesion deficiency type 1.

Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1.

Preclinical safety and efficacy of lentiviral-mediated gene therapy for leukocyte adhesion deficiency type I.

Impairment of cytokine production following immunological synapse formation in patients with Wiskott-Aldrich syndrome and leukocyte adhesion deficiency type 1.

β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis.

Healing With Complication: An Unusual Case of Nasal Tip Ulceration in Leukocyte Adhesion Deficiency Type 1.

Incorporation of fucose into glycans independent of the GDP-fucose transporter SLC35C1 preferentially utilizes salvaged over de novo GDP-fucose.

Neutrophil-Specific Knockdown of β2 Integrins Impairs Antifungal Effector Functions and Aggravates the Course of Invasive Pulmonal Aspergillosis.

Selectin-Mediated Signaling-Shedding Light on the Regulation of Integrin Activity in Neutrophils.

Understanding the Role of LFA-1 in Leukocyte Adhesion Deficiency Type I (LAD I): Moving towards Inflammation?

Defining the mild variant of leukocyte adhesion deficiency type II (SLC35C1-congenital disorder of glycosylation) and response to l-fucose therapy: Insights from two new families and review of the literature.

Premature Loss of Deciduous Teeth as a Symptom of Systemic Disease: A Narrative Literature Review.

Oral Ulcers Resolution Using IL12/23 Blockade in an Infant with Leukocyte Adhesion Deficiency Type 1.

Novel ITGB2 Mutation Is Responsible for a Severe Form of Leucocyte Adhesion Deficiency Type 1.

Successful allogeneic stem cell transplantation with a reduced-intensity conditioning in a case of leukocyte adhesion deficiency type III.

Examining the Effect of Kindlin-3 Binding Site Mutation on LFA-1-ICAM-1 Bonds by Force Measuring Optical Tweezers.

T-Cell Adhesion in Healthy and Inflamed Skin.

An adult with severe leukocyte adhesion deficiency type 1.

Frequency of genotypic markers for genetic disorders, colour, polledness, and major genes in Blanco Orejinegro cattle.

Molecular Insights Into Neutrophil Biology From the Zebrafish Perspective: Lessons From CD18 Deficiency.

Case Report: A Case of Leukocyte Adhesion Deficiency, Type III Presenting With Impaired Platelet Function, Lymphocytosis and Granulocytosis.

Novel FERMT3 and PTPRQ Mutations Associated with Leukocyte Adhesion Deficiency-III and Sensorineural Hearing Loss.

A novel ITGB2 variant with long survival in patients with leukocyte adhesion defect type-I.

A doggy tale: Risk of zoonotic infection with Bordetella bronchiseptica for cystic fibrosis (CF) patients from live licenced bacterial veterinary vaccines for cats and dogs.

Clinical and laboratory findings in patients with leukocyte adhesion deficiency type I: A multicenter study in Turkey.

Perinatal Inflammation: Could Partial Blocking of Cell Adhesion Molecule Function Be a Solution?

Prevalence of nine genetic defects in Chinese Holstein cattle.

Leukocyte Adhesion Deficiency Type 1 Due to Novel ITGB2 Mutation.

Gene Therapies for Primary Immune Deficiencies.

Pyoderma Gangrenosum with an Underlying Leukocyte Adhesion Deficiency Type 1 (LAD-1) and Pregnancy in the Shade of COVID-19 Epidemic: A Patient and Physician Experience.

Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency type I and III.

Clinical and Genetic Spectrum of a Large Cohort of Patients With Leukocyte Adhesion Deficiency Type 1 and 3: A Multicentric Study From India.

Kindlin3-Dependent CD11b/CD18-Integrin Activation Is Required for Potentiation of Neutrophil Cytotoxicity by CD47-SIRPα Checkpoint Disruption.

Genome editing in human hematopoietic stem and progenitor cells via CRISPR-Cas9-mediated homology-independent targeted integration.

Incidental diagnosis of leukocyte adhesion deficiency type II following ABO typing.

CIN or not: An approach to the evaluation and management of chronic idiopathic neutrophilia.

The spectrum of primary immunodeficiencies at a tertiary care hospital in Pakistan.

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling.

Primary Immunodeficiencies With Defects in Innate Immunity: Focus on Orofacial Manifestations.

Frontline Science: Activation of metabolic nuclear receptors restores periodontal tissue homeostasis in mice with leukocyte adhesion deficiency-1.

β2 Integrin Gene (ITGB2) mutation spectra in Pakistani families with leukocyte adhesion deficiency type 1 (LAD1).

Impact of gene therapy for canine monogenic diseases on the progress of preclinical studies.

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.

Successful umbilical cord blood transplantation in children with leukocyte adhesion deficiency type I.

β2 Integrins-Multi-Functional Leukocyte Receptors in Health and Disease.

Successful hematopoietic stem cell transplant in leukocyte adhesion deficiency type III presenting primarily as malignant infantile osteopetrosis.

MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-β1 levels.

Distinct Contributions of CD18 Integrins for Binding and Phagocytic Internalization of Pseudomonas aeruginosa.

Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases: A Single Center Experience.

New developments in neutrophil biology and periodontitis.

Neutrophil Defects and Diagnosis Disorders of Neutrophil Function: An Overview.

Novel variants in FERMT3 and RASGRP2-Genetic linkage in Glanzmann-like bleeding disorders.

Technical note: Development and application of KASP assays for rapid screening of 8 genetic defects in Holstein cattle.

Late diagnosis of leukocyte adhesion deficiency type II and Bombay blood type in a child: a rare case report.

Neutrophil phenotypes in chronic lung disease.

Force-Directed "Mechanointeractome" of Talin-Integrin.

Haploidentical stem cell transplantation with post-transplant cyclophosphamide in leukocyte adhesion deficiency type 1: a case report.

A novel mutation of the ITGB2 gene in a Chinese Zhuang minority patient with leukocyte adhesion deficiency type 1 and glucose-6-phosphate dehydrogenase deficiency.

Adhesive dynamics simulations quantitatively predict effects of kindlin-3 deficiency on T-cell homing.

CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites.

Efficiency of different fragment lengths of the ubiquitous chromatin opening element HNRPA2B1-CBX3 in driving human CD18 gene expression within self-inactivating lentiviral vectors for gene therapy applications.

A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.

Primary Immunodeficiency Disorders Among North Indian Children.

A Novel Nonsense Mutation in FERMT3 Causes LAD-III in a Pakistani Family.

Report of a Chinese Cohort with Leukocyte Adhesion Deficiency-I and Four Novel Mutations.

Inflammatory consequences of inherited disorders affecting neutrophil function.

Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease.

Type I leucocyte adhesion deficiency in Yemenian family managed with appropriate treatment: A case series.

CD11b Regulates Fungal Outgrowth but Not Neutrophil Recruitment in a Mouse Model of Invasive Pulmonary Aspergillosis.

Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis.

Proteome Analysis of Human Neutrophil Granulocytes From Patients With Monogenic Disease Using Data-independent Acquisition.

Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis.

Leucocyte adhesion deficiency-A multicentre national experience.

The Oral Microbiota Is Modified by Systemic Diseases.

CD18 is redundant for the response to multiple vaccines: A case study.

Pyoderma Gangrenosum-like Wounds in Leukocyte Adhesion Deficiency: Case Report and Review of Literature.

ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression.

Palatal Ulcer in Leukocyte Adhesion Deficiency: an Unusual Occurrence.

[Novel mutations of ITGB2 induced leukocyte adhesion defect type 1].

Novel Mutations in the β2 Integrin Gene (ITGB2) in a Moderate Leukocyte Adhesion Defect type 1 Patient.

Leukocyte Adhesion Deficiency Type 1 with Low Expression of CD 11b.

Genetic Analysis of 13 Iranian Families With Leukocyte Adhesion Deficiency Type 1.

Long term outcome of eight patients with type 1 Leukocyte Adhesion Deficiency (LAD-1): Not only infections, but high risk of autoimmune complications.

Evaluation of infectious and non-infectious complications in patients with primary immunodeficiency.

Long-term management of leukocyte adhesion deficiency type III without hematopoietic stem cell transplantation.

T-ARMS PCR genotyping of SNP rs445709131 using thermostable strand displacement polymerase.

An International Genetic Survey of Breed-Specific Diseases in Working Dogs from the United States, Israel, and Poland.

Leukocyte adhesion defect: An uncommon immunodeficiency.

Leukocyte adhesion deficiency-I: A comprehensive review of all published cases.

Allogeneic Hematopoietic Stem Cell Transplantation for Leukocyte Adhesion Deficiency.

Diagnosis of platelet function disorders: A standardized, rational, and modular flow cytometric approach.

Dental implants in a patient with suspected leucocyte adhesion deficiency.

Leukocyte adhesion defect-I: rare primary immune deficiency.

Primary Immunodeficiency Diseases: Current and Emerging Therapeutics.

Hematopoietic stem cell transplantation for the treatment of leukocyte adhesion deficiency type III.

Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin β2 (ITGB2) gene.

Structural basis of kindlin-mediated integrin recognition and activation.

Necrotizing Ulcer After BCG Vaccination in a Girl With Leukocyte-adhesion Deficiency Type 1.

Mutation characterization and heterodimer analysis of patients with leukocyte adhesion deficiency: Including one novel mutation.

Biological functions of fucose in mammals.

Hematopoietic Stem Cell Transplantation in Primary Immunodeficiency Patients in the Black Sea Region of Turkey.

Beta2 integrins are required for follicular helper T cell differentiation in humans.

Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1.

Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions.

Leukocyte adhesion deficiency type I: A rare primary immunodeficiency disorder.

Leukocyte Adhesion Deficiency III: Report of Two Siblings.

A Review of Selected Genes with Known Effects on Performance and Health of Cattle.

Primary immune deficiencies with defects in neutrophil function.

Case 1: Recurrent Omphalitis and Nonhealing Ulcers in a 7-month-old Girl.

The role of kindlin in neutrophil recruitment to inflammatory sites.

Production and purification of high-titer foamy virus vector for the treatment of leukocyte adhesion deficiency.

Development of a fast and economical genotyping protocol for bovine leukocyte adhesion deficiency (BLAD) in cattle.

Leukocyte Adhesion Deficiency Type 1 (LAD1) with Expressed but Nonfunctional CD11/CD18.

Brain Abscess in a Child with Leukocyte Adhesion Defect: An Unusual Association.

Phenotypic and genetic effects of recessive haplotypes on yield, longevity, and fertility.

Leukocyte Adhesion Deficiency IV. Monocyte Integrin Activation Deficiency in Cystic Fibrosis.

Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I.

Hematopoietic Stem Cell Transplant for Primary Immunodeficiency Diseases: A Single-Center Experience.

Immune and regulatory functions of neutrophils in inflammatory bone loss.

Leukocyte Adhesion Deficiency-I: Clinical and Molecular Characterization in an Indian Population.

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.

The kindlin family: functions, signaling properties and implications for human disease.

Mutations of Cystic Fibrosis Transmembrane Conductance Regulator Gene Cause a Monocyte-Selective Adhesion Deficiency.

Mutation spectra of the ITGB2 gene in Iranian families with leukocyte adhesion deficiency type 1.

Investigation of ITGB2 gene in 12 new cases of leukocyte adhesion deficiency-type I revealed four novel mutations from Iran.

Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice.

Highlighting the problematic reliance on CD18 for diagnosing leukocyte adhesion deficiency type 1.

Role of bacteria in leukocyte adhesion deficiency-associated periodontitis.

Adaptive immune defects in a patient with leukocyte adhesion deficiency type III with a novel mutation in FERMT3.

Loss of the Rap1 effector RIAM results in leukocyte adhesion deficiency due to impaired β2 integrin function in mice.

Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.

Budd-Chiari Syndrome in a Child With Leukocyte Adhesion Deficiency-A Rare Association.

Neutrophil functional disorder in childhood.

Interaction of kindlin-3 and β2-integrins differentially regulates neutrophil recruitment and NET release in mice.

Optimal T Cell Activation and B Cell Antibody Responses In Vivo Require the Interaction between Leukocyte Function-Associated Antigen-1 and Kindlin-3.

Leukocyte adhesion deficiency-I with a novel intronic mutation presenting with pyoderma gangrenosum- like lesions.

Leucocyte adhesion deficiency type 1 with developmental delay secondary to CMV infection and filiation questions.

A new mutation in the KINDLIN-3 gene ablates integrin-dependent leukocyte, platelet, and osteoclast function in a patient with leukocyte adhesion deficiency-III.

Epithelial adhesion molecules and the regulation of intestinal homeostasis during neutrophil transepithelial migration.

Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Molecular characterization of leukocyte adhesion deficiency-I in Indian patients: identification of 9 novel mutations.

The enduring importance of animal models in understanding periodontal disease.