Corneal thinning and perforation: a narrative review of diagnostic and stepwise management strategies.

Systematic Literature Review on the Effect of Cenegermin on Corneal Sensation and Innervation in Patients with Neurotrophic Keratopathy.

The Role of Innervation in Ocular Surface Homeostasis, Tissue Remodeling Following Nerve Injury, and the Therapeutic Potential of Hemocomponents in Neuronal and Cicatricial Pathologies.

[Recurrence of herpetic eye disease following cataract surgery: risk factors and prevention].

Clinical evidence on allogeneic blood-derived eye drops in ocular surface and corneal diseases.

Cross face nerve grafting for reinnervation of nasal and tongue mucosa following trigeminal nerve injury.

Recovery of corneal sensation following eyelid surgery for neurotrophic keratopathy and preganglionic facial palsy.

Neurotrophic keratopathy in childhood: advances in understanding of pathogenesis and management.

Proteomic analysis of corneal epithelial cells in patients with neurotrophic keratopathy.

Molecular landscape connecting complications of dry eye disease: mechanisms, therapeutic targets, biomarkers, and future innovations.

Association Between Neurotrophic Keratitis and Limbal Stem Cell Deficiency.

Management of persistent corneal epithelial defects: role of insulin.

Neurotrophic keratopathy patients after minimally invasive corneal neurotization treated with RhNGF eyedrops: a case series.

Letter to Editor: Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns.

Shelf-Stable, Cryopreserved Amniotic Membrane for the Management of Ocular Surface Disease: A Retrospective Assessment.

Real-world effectiveness of topical insulin for neurotrophic keratopathy: retrospective case series of 29 eyes.

Neurotrophic Keratopathy in Herpes Zoster Ophthalmicus.

Long-term outcomes of corneal neurotization for neurotrophic keratopathy: a dual center, single surgeon retrospective study.

Indirect Corneal Neurotization Using the Infraorbital Nerve and Sural Nerve Interposition Graft: A Case Report.

Therapeutic Outcomes of Shelf-Stable, Cryopreserved Amniotic Membrane in Recalcitrant Keratopathy.

Medical and surgical interventions for neurotrophic keratopathy.

In vivo confocal microscopy (IVCM) analysis of corneal sub-basal nerve plexus (SNP) and corneal sensitivity after micropulse transscleral cyclophotocoagulation (MP-TSCPC) in glaucoma patients.

Alterations of the ocular surface during diabetes: molecular mechanisms and therapeutic strategies.

Polyneuritis cranialis following actinomycosis of a wisdom tooth: a case report.

Outcome of Cenegermin in the Treatment of Neurotrophic Keratopathy.

Aging and Corneal Nerve Health: Mechanisms of Degeneration and Emerging Therapies for the Cornea.

AQP5 Regulates Corneal Nerve Distribution Through NETRIN-1 and SLIT3.

Anesthetic Considerations in Pediatric Corneal Neurotization: A Case Report.

New Phenotype in Two Siblings with Familial FLVCR1 Mutation: Neurotrophic Keratopathy.

Clinical Outcomes of Corneal Neurotization in Patients With Herpetic Neurotrophic Keratopathy.

Efficacy of Corneal Neurotization Surgery in Eyes With Neurotrophic Keratopathy: A Systematic Review and Meta-Analysis.

Cenegermin for the Treatment of Moderate or Severe Neurotrophic Keratopathy: Results from a Prospective, Phase IV, Open-Label Study in China.

Management of refractory persistent epithelial defect treatment with topical insulin: An Indian pilot study.

The role of limbal stem cells on neurotrophic cornea.

Severe Aqueous-Deficient Dry Eye Following Herpes Zoster Ophthalmicus With Periocular Inflammation: A Case Series.

Indirect Corneal Neurotization: Long-Term Outcomes Using a Sural Nerve Graft in Patients With Facial Palsy and Neurotrophic Keratopathy.

Topical Cenegermin for Pediatric Neurotrophic Keratopathy: A Review of the Literature and Systematic Review.

Congenital Corneal Anesthesia Secondary to Brainstem Ischemia as a Rare Complication of Neonatal Hypoxic-Ischemic Encephalopathy.

Corneal neurotization meets COVID-19: a case report of minimally invasive corneal neurotization complicated by COVID-19-related keratitis.

Oculoplastic Interventions in the Management of Ocular Surface Diseases: A Comprehensive Review.

The Therapeutic Potential of Insulin Eye Drops in Neurotrophic Keratopathy: A Comprehensive Review.

Evaluation of Corneal Sensitivity: Tools We Have.

Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns.

Real-World Outcomes of Allogeneic Immunosafe Plasma Rich in Growth Factors Eye Drops for Refractory Ocular Surface Diseases: A Prospective Observational Study.

Impact of topical insulin as a therapeutic intervention for corneal wounds: A comprehensive systematic review and meta-analysis.

Cenegermin treatment for pediatric neurotrophic keratopathy: a systematic review.

Utility of cenegermin for the management of neurotrophic keratopathy after penetrating keratoplasty.

Minimally invasive corneal neurotization surgery and outcomes in a rural population.

The Role of Nerve Growth Factor on the Ocular Surface: A Review of the Current Experimental Research and Clinical Practices.

Corneal Neurotization Using the Supratrochlear Nerve With a Great Auricular Nerve Graft for Neurotrophic Keratopathy: Long-Term Results.

Periocular Management of Pediatric Facial Nerve Palsy.

Corneal Sensory Denervation Causes Epithelial Ferroptosis and Delayed Healing in Mice.

Corneal Neurotization in Elderly Patients with Multimorbidity.

Topical insulin as a novel treatment for persistent epithelial defects and other ocular surface disorders: a systematic review.

Impact of neurotrophic keratopathy on quality of life: a utility analysis.

Outcomes of Corneal Transplantation After Minimally Invasive Corneal Neurotization in Children.

Corneal Neurotization: Paving the Path to Reinnervation.

Corneal Neurotization, Recent Progress, and Future Perspectives.

Neurotrophic Keratopathy in Pediatric Population: An IRIS® Registry Report.

Corneal neurotization for the treatment of neurotrophic keratopathy.

A Narrative Medicine Approach to Navigating Barriers to the Diagnosis of Pediatric Neurotrophic Keratopathy.

Biological topicals in ocular surface disorders.

Neurotrophic keratopathy: Update in diagnosis and management.

Bilateral In Vivo Confocal Microscopic Changes of the Corneal Subbasal Nerve Plexus in Patients with Acute Herpes Zoster Ophthalmicus.

In Vitro Evaluation of Gelatin-Based Hydrogels as Potential Fillers for Corneal Wounds.

[Neurotrophic keratopathy and corneal ulcers in diabetes mellitus].

Corneal Recovery After Neurotization for Neurotrophic Keratopathy.

Preliminary report of minimally invasive corneal neurotization in patients with neurotrophic keratopathy in Southern China.

Sandwich Technique and Amniotic Membrane Transplantation as an Effective Method in Repairing Corneal Perforations.

Corneal Ring Infiltrate Following Micropulse Cyclophotocoagulation.

Disrupted Mitochondrial Dynamics Impair Corneal Epithelial Healing in Neurotrophic Keratopathy.

Techniques in Corneal Neurotization.

Topical insulin in pediatric neurotrophic keratopathy associated with CIPA syndrome.

Nerve growth factor loaded hypotonic eye drops for corneal nerve repair.

Incidence of corneal perforation and lagophthalmos in patients with leprosy in Japan based on 40-year observations.

Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial.

Autologous blood in the management of ocular surface disorders.

The role of lysophosphatidic acid and its receptors in corneal nerve regeneration.

Topical insulin used alone or in combination with drug-depository contact lens for refractory cases of neurotrophic keratopathy.

Conjunctival Neuroma After Corneal Neurotization in a Patient With Neurotrophic Keratopathy.

The THINK Study: Testing Hypoesthesia and the Incidence of Neurotrophic Keratopathy in Cataract Patients with Dry Eye.

Neuronal Intranuclear Inclusion Disease with a Corneal Disorder: A Case Report.

Comparison of Cochet-Bonnet, Dental Floss, and Cotton Wisp With Applications to Corneal Sensation Testing.

Long-term outcomes of sural nerve vertical cross-face graft for lacrimal gland neurotization in neurodeprivative dry eye.

Scleritis and episcleritis in patients with idiopathic small fiber neuropathy.

Concurrent Limbal Stem Cell Deficiency and Mild Neurotrophic Keratopathy in Graft-Vs-Host Disease.

Can Inactivated Coronavirus Disease 2019 Vaccine Cause Bilateral Neurotrophic Keratopathy?

Topical Insulin for Neurotrophic-Related Epithelial Defects: Where do We Stand? A Systematic Review.

Nerve Growth Factor Treatment for Neurotrophic Keratopathy in the IRIS® Registry.

Topical Application of 0.05% Cyclosporine for the Treatment of Neurotrophic Keratopathy Secondary to Herpes Simplex Keratitis.

Preventing and treating neurotrophic keratopathy by a single intrastromal injection of AAV-mediated gene therapy.

Current perspectives and concerns in corneal neurotization.

Single-Stage Bilateral Corneal Neurotization for Neurotrophic Keratopathy in Stüve-Wiedemann Syndrome: A Case Report and Literature Review.

Long-Term Evaluation of Patients with Neurotrophic Keratopathy Undergoing Staged Keratoplasty After Corneal Neurotization.

Corneal reinnervation in patients with severe neurotrophic keratopathy secondary to herpes zoster ophthalmicus after treatment with autologous serum tear drops.

Clodronate liposome treatment contributes to the nerve regeneration in corneal nerve involvement of diabetic mice.

The use of rh-NGF in the management of neurotrophic keratopathy.

Detection of Subclinical Neurotrophic Keratopathy by Noncontact Esthesiometry.

The Utilization of Topical Insulin for Ocular Surface Diseases: A Narrative Review.

Tear Fluid Progranulin as a Noninvasive Biomarker for the Monitoring of Corneal Innervation Changes in Patients With Type 2 Diabetes Mellitus.

Co-existence of Neurotrophic Keratopathy in Eyes With Limbal Stem Cell Deficiency.

Development and Characterization of a Photocrosslinkable, Chitosan-Based, Nerve Growth Factor-Eluting Hydrogel for the Ocular Surface.

Corneal Nerve Assessment by Aesthesiometry: History, Advancements, and Future Directions.

Topical insulin in neurotrophic keratopathy after diabetic vitrectomy.

Neurotrophic keratopathy: General features and new therapies.

Insights on the Choice and Preparation of the Donor Nerve in Corneal Neurotization for Neurotrophic Keratopathy: A Narrative Review.

Iris neovascularization and neurotrophic keratopathy following ultrasound cycloplasty in refractory glaucoma: case series.

Corneal Neurotization for Neurotrophic Keratopathy: A Multicenter Experience.

The role of topical insulin in ocular surface restoration: A review.

Predictive performance of corneal and lid margin sensitivity for dry eye disease: An investigator-masked, prospective, prognostic accuracy study.

Substance P promotes transforming growth factor-β-induced collagen synthesis in human corneal fibroblasts.

Outcomes of Boston Keratoprosthesis Type I Implantation in Poland: A Retrospective Study on 118 Patients.

Neurotrophic Keratopathy in Marfan Syndrome Patient After Micropulse Transscleral Cyclophotocoagulation: A Call for Risk Stratification.

Corneal Neurotization: Essentials for The Facial Paralysis Surgeon.

Establishment of mouse model of neurotrophic keratopathy through TRPV1 neuronal ablation.

Topical Insulin in Neurotrophic Keratopathy: A Review of Current Understanding of the Mechanism of Action and Therapeutic Approach.

Neurotrophic Keratopathy after wide retinal endolaser and postoperative Ketorolac eye drops: A case series.

Minimally Invasive Corneal Neurotization: 10-Year Update in Technique Including Novel Donor Transfer of the Great Auricular Nerve.

Phase IV Multicenter, Prospective, Open-Label Clinical Trial of Cenegermin (rhNGF) for Stage 1 Neurotrophic Keratopathy (DEFENDO).

Neurotrophic keratopathy: Clinical presentation and outcomes in 354 eyes in a community-based population.

A New Treatment for Recalcitrant Neurotrophic Keratopathy of Ocular Graft-Versus-Host Disease with Virus Infection.

Diagnostic performance of real-time quantitative PCR in tear samples in various subtypes of herpes simplex keratitis.

Corneal Superficial Plaque Formation After Recombinant Human Nerve Growth Factor Use in a Patient With Neurotrophic Keratopathy and Limbal Stem Cell Deficiency From Mucous Membrane Pemphigoid.

Clinical outcomes of corneal neurotization using sural nerve graft in neurotrophic keratopathy.

Effect of recombinant human nerve growth factor treatment on corneal nerve regeneration in patients with neurotrophic keratopathy.

Neurotrophic Keratopathy and Topical Insulin Therapy: A Case Report.

Outcomes and success of amniotic membrane transplantation for the treatment of corneal diseases.

Corneal Neurotization: Preoperative Patient Workup and Surgical Decision-making.

Indications and outcomes of keratoplasty ≤ 5.5 mm diameter ("mini-keratoplasty").

Chitosan-based thermosensitive hydrogel with long-term release of murine nerve growth factor for neurotrophic keratopathy.

Use of PROSE for long-term ocular surface support in patients with a permanent keratoprosthesis.

Herpes simplex virus keratitis: electronic medical records driven big data analytics report from a tertiary eye institute of South India.

Neurotrophic keratopathy: An updated understanding.

Corneal Sensitivity Is Inversely Correlated With Severity of Diabetic Retinopathy in a Predominantly Underrepresented Population.

The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal.

Semiscleral Contact Lens Use After Direct Corneal Neurotization for Neurotrophic Keratopathy.

Efficacy of the Buried Temporary Suture Tarsorrhaphy: A Novel Technique.

Ocular adverse events of cenegermin used in neurotrophic keratopathy: an analysis of the FDA adverse event reporting system database.

Combined Use of Therapeutic Hyper-CL Soft Contact Lens and Insulin Eye Drops for the Treatment of Recalcitrant Neurotrophic Keratopathy.

Neurotrophic keratopathy associated with cancer immunotherapy targeting programmed death 1.

Neurotrophic Keratopathy After Slow Coagulation Transscleral Cyclophotocoagulation.

Evaluation of Corneal Nerve Regeneration After Minimally Invasive Corneal Neurotization.

Clinical associations of corneal neuromas with ocular surface diseases.

Urokinase-type plasminogen activator promotes corneal epithelial migration and nerve regeneration.

Ocular-Surface Regeneration Therapies for Eye Disorders: The State of the Art.

New Promising Therapeutic Approach for Refractory Corneal Epithelial Defects.

Neurotrophic keratopathy following rhegmatogenous retinal detachment surgery.

Detection of Subclinical Neurotrophic Keratopathy by Non-Contact Esthesiometry.

Trigeminal nerve-derived substance P regulates limbal stem cells by the PI3K-AKT pathway.

Guillain-Barré Syndrome With Associated Bilateral Neurotrophic Keratopathy.

Prevalence and clinical characteristics of neurotrophic keratopathy in hispanic population in northeastern Mexico.

Autologous serum eye drops in dry eye disease: Preferred practice pattern guidelines.

[Advancements in corneal sensory reconstruction for the treatment of neurotrophic keratopathy].

Corneal Neurotization-Indications, Surgical Techniques and Outcomes.

Cenegermin for the treatment of dry eye disease.

Cost and Prescriber and Patient Characteristics of Cenegermin Use in the Medicare Population.

Noxious effects of riot control agents on the ocular surface: Pathogenic mechanisms and management.

Umbilical Cord Graft for Refractory Neurotrophic Keratopathy.

Applications of mesenchymal stem cells in ocular surface diseases: sources and routes of delivery.

Minimally invasive corneal neurotization for neurotrophic keratopathy: The potential effect of age, denervation chronicity and lesion location.

Phialophora chinensis fungal keratitis: An initial case report and species identification.

Can Nerve Growth Factor (NGF) Be a Treatment Option for Pediatric Eye Diseases?

Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study.

0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial.

[Modern capabilities in diagnosis and treatment of neurotrophic keratopathy].

Corneal neurotization in the management of neurotrophic keratopathy: A review of the literature.

Observational study of cenegermin for the treatment of limbal stem cell deficiency associated with neurotrophic keratopathy.

Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions.

Bilateral Corneal Neurotization for Ramos-Arroyo Syndrome and Developmental Neurotrophic Keratopathy: Case Report and Literature Review.

[CORNEAL NEUROTIZATION FOR NEUROTROPHIC KERATOPATHY].

Neurotrophic Keratopathy Treated with Topical Recombinant Human Nerve Growth Factor (Cenegermin): Case Series Study with Long-Term Follow-Up.

Ophthalmic findings of congenital insensitivity to pain with anhidrosis with a novel neurotrophic tyrosine kinase receptor type 1 gene mutation: A case report.

Waardenburg syndrome-associated neurotrophic keratopathy in a child treated with neurotization surgery.

Medium-term Outcomes of Micropulse Transscleral Cyclophotocoagulation in Refractory Glaucoma.

Ocular manifestations among patients with congenital insensitivity to pain due to variants in PRDM12 and SCN9A genes.

Sustained Release of Tacrolimus From a Topical Drug Delivery System Promotes Corneal Reinnervation.

Efficacy of Recombinant Human Nerve Growth Factor in Stage 1 Neurotrophic Keratopathy.

Exploration of biomimetic poly(γ-benzyl-L-glutamate) fibrous scaffolds for corneal nerve regeneration.

Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy.

[Autologous serum eye drops for therapy-resistant epithelial defects of the cornea : Impact of underlying disease and simultaneous amniotic transplantation in 990 applications].

Physicochemical and microbiological stability of insulin eye drops in an artificial tear vehicle used in the treatment of refractory neurotrophic keratopathy.

Prevalence of neurotrophic keratopathy in patients with chronic ocular graft-versus-host disease.

Aberrant Corneal Homeostasis in Neurosurgery-Induced Neurotrophic Keratopathy.

[Treatment of neurotrophic keratopathy in combined lesions of the trigeminal and facial nerves].

Neurotrophic Keratopathy in the United States: An Intelligent Research in Sight Registry Analysis.

Prophylactic Laser Treatment Posterior to Pars Plana Vitrectomy Sclerotomy Wounds During Macular Surgery.

Complications in Retinal Surgery: A Review of Corneal Changes Following Vitreoretinal Procedures.

Recombinant Human Nerve Growth Factor for Pediatric Neurotrophic Keratopathy.

Neurotrophic Keratopathy in Systemic Diseases: A Case Series on Patients Treated With rh-NGF.

Minimally invasive, indirect corneal neurotization using an ipsilateral sural nerve graft for early neurotrophic keratopathy.

Neurotization of the human cornea - A comprehensive review and an interim report.

Neurotrophic Keratitis Due to Congenital Corneal Anesthesia with Deafness, Hypotonia, Intellectual Disability, Face Abnormality and Metabolic Disorder: A New Syndrome?

Minimally Invasive Corneal Neurotization Provides Sensory Function, Protects Against Recurrent Ulceration, and Improves Visual Acuity.

A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America.

Clinical and instrumental assessment of the corneal healing in moderate and severe neurotrophic keratopathy treated with rh-NGF (Cenegermin).

Topical cenegermin 0.002% for pediatric neurotrophic keratopathy.

Neurotrophic keratopathy: Clinical presentation and effects of cenegermin.

The Role of Hi-Tech Devices in Assessment of Corneal Healing in Patients with Neurotrophic Keratopathy.

Pillar tarsoconjunctival flap: An alternative approach for the management of refractory corneal ulcer.