Pular para o conteúdo
Endoftalmite
ORPHA:199323CID-10 · H44.0CID-11 · 9C21DOENÇA RARA
Visão / ocular

Uma infecção que atinge as partes de dentro do olho.

Última verificação: Fonte: sem afirmação sobre o SUS a verificarEm construçãohistóricoSugerir correção
Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

💬
EM LINGUAGEM SIMPLES

A endoftalmite é uma infecção grave que atinge as partes de dentro do globo ocular. A pessoa pode notar sinais marcantes como olho vermelho, dor intensa, intolerância à luz e visão turva ou enfraquecida. A condição não é causada por defeitos genéticos familiares, decorrendo frequentemente de agentes infecciosos. No Brasil, a enfermidade não possui um protocolo oficial (PCDT) próprio para doenças raras no SUS, sendo o suporte prestado pela rede oftalmológica assistencial.

📋
Informacoes curadas por IA — podem conter imprecisoes

Uma infecção que atinge as partes de dentro do olho.

Pesquisas ativas
8 ensaios
65 total registrados no ClinicalTrials.gov
Publicações científicas
10.886 artigos
Último publicado: 2026
Em pesquisa
3 moléculas
PREDNISOLONE PHOSPHORIC ACID, SARGRAMOSTIM, PREDNISOLONE SODIUM PHOSPHATE

O que está sendo pesquisado

3 moléculas em estudo — nenhuma com registro para esta doença
Ver detalhes e fases →
PREDNISOLONE PHOSPHORIC ACIDSARGRAMOSTIMPREDNISOLONE SODIUM PHOSPHATE
Aparecer aqui significa que a molécula foi estudada nesta doença, não que trate. Converse com seu médico.
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: H44.0
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Características mais comuns

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Uveíte anterior
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Perfuração corneana
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Anormalidade do segmento posterior do globo ocular
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Catarata
—
Atrofia da íris
—
Edema estromal da córnea
29sintomas
Sem dados (29)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 29 características clínicas mais associadas, ordenadas por frequência.

Uveíte anteriorAnterior uveitis
Perfuração corneanaCorneal perforation
Anormalidade do segmento posterior do globo ocularAbnormality of the posterior segment of the globe
CatarataCataract
Atrofia da írisIris atrophy

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico10.886PubMed
Últimos 10 anos200publicações
Pico2026126 papers
Linha do tempo
2026Hoje · 2026🧪 1990Primeiro ensaio clínico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
✓Aprovado11
3Fase 38
2Fase 210
1Fase 11
·Pré-clínico38
Medicamentos catalogadosEnsaios clínicos· 3 medicamentos · 65 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Endoftalmite

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Onde estão os ensaios

Com ensaio aberto em 8 países. O ponto verde marca onde há vaga agora.

🟢 Recrutando agora

3 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

65 ensaios clínicos encontrados, 8 ativos.

Distribuição por fase
NCT03244072 · Safety and Efficacy of Intracameral Zimoxin for Prevention o…Em breve
PHASE2, PHASE3🇺🇸 Estados Unidos
NCT07850414 · Intracameral Levofloxacin Versus Moxifloxacin After Cataract…Em breve
NA
NCT06673784 · Evaluation and Risk Factors of Post-traumatic Endophthalmiti…Em breve
NCT07262437 · Targeting Immunosuppressive Treatment for Non-infectious Uve…Ativo
NA🇮🇹 Itália
NCT07176130 · Demographics and Clinical Characteristics of Ocular Inflamma…Ativo
Singapore
NCT04192994 · Evaluation do Early Pars Plana Vitrectomy in Acute Endophtha…Concluído
NA🇧🇷 Brasil
NCT03363295 · Evaluation of Macular Changes After Intracameral Moxifloxaci…Concluído
PHASE4🇧🇷 Brasil
NCT02595359 · Intracameral Moxifloxacin for Prevention of Postcataract End…Concluído
PHASE2🇧🇷 Brasil
NCT01739920 · Comparative Efficacy of Different Regimens of PVPI 5% Eye Dr…Concluído
PHASE4🇧🇷 Brasil
NCT07514845 · First-line Surgical Versus Medical Treatment: A Retrospectiv…Concluído
🇫🇷 França
NCT06755177 · Clinical Features and Visual Prognosis of Infectious Endopht…Concluído
🇨🇳 China
NCT05413980 · Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride …Concluído
🇮🇳 Índia
NCT06990607 · Compare PPV With and Without Silicone Oil in Managing Postop…Concluído
NA🇪🇬 Egito
NCT07717944 · Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-…Concluído
NA🇪🇬 Egito
NCT05791695 · A Study of the Incidence of Intraocular Inflammation and Sus…Concluído
🇺🇸 Estados Unidos
NCT04522661 · A Feasibility Randomised Controlled Trial of Early Vitrectom…Concluído
NA🇬🇧 Reino Unido
NCT05428683 · Intravitreal Triamcinolone and Moxifloxacin Injection After …Concluído
NA🇪🇬 Egito
NCT04568213 · Hypochlorous Acid Disinfection Prior to Cataract SurgeryConcluído
PHASE3🇺🇸 Estados Unidos
NCT04456556 · Combined Endophthalmitis and Orbital Cellulitis in Patients …Concluído
🇪🇬 Egito
NCT03687931 · A Clinical Study to Assess the Efficacy and Safety of Dexame…Concluído
PHASE1, PHASE2🇺🇸 Estados Unidos
NCT03553017 · The EXPLORE Study - The Use of Binocular OCT Imaging for the…Concluído
🇬🇧 Reino Unido
NCT03958292 · Conjunctival Flora Before Cataract Surgery: a Microbiologica…Concluído
NA🇮🇹 Itália
NCT04403334 · Postoperative Safety Outcomes of Intraoperative Intracameral…Concluído
PHASE4Philippines
NCT03317847 · Bromfenac Versus Dexamethasone After Cataract SurgeryConcluído
PHASE4🇮🇹 Itália
NCT03634852 · A Two Chemoprophylaxis Approaches After Phacoemulsification …Concluído
PHASE4
NCT05249413 · Early Vitrectomy for Endophthalmitis After Cataract SurgeryConcluído
🇪🇬 Egito
NCT02065375 · RTA 408 Ophthalmic Suspension for the Treatment of Ocular In…Concluído
PHASE2🇺🇸 Estados Unidos
NCT01323868 · Endogenous Endophthalmitis in the Inpatient SettingConcluído
🇺🇸 Estados Unidos
NCT00461656 · Povidone-iodine Antisepsis for Strabismus SurgeryConcluído
PHASE4🇩🇪 Alemanha · 🇳🇱 Países Baixos
NCT01768078 · Interest of Intravitreal Corticotherapy as the First-line Tr…Concluído
PHASE3🇫🇷 França
NCT00690313 · Dosage Study for Vigamox Eye Drops Prior to Intravitreal Inj…Concluído
PHASE4🇺🇸 Estados Unidos
NCT00730938 · The Effect of Intracameral Cefuroxime on Post-op Fibrin in P…Concluído
NAKenya
NCT02818062 · Severe Intraocular InfectionConcluído
🇫🇷 França
NCT00406913 · Prophylaxis Prior to Cataract Surgery Conjunctival Flora and…Concluído
NA🇺🇸 Estados Unidos
NCT00491049 · Effectiveness of Topical 0.5% Levofloxacin to Reduce the Con…Concluído
PHASE4🇩🇪 Alemanha
NCT00136344 · Study of Antibiotic Prophylaxis for Endophthalmitis Followin…Concluído
NA🇦🇹 Áustria · 🇧🇪 Bélgica · 🇩🇪 Alemanha +6
NCT00398658 · Prophylaxis of Acute Post-Traumatic Bacterial Endophthalmiti…Concluído
PHASE4Iran
NCT00001734 · Screening for NEI Clinical StudiesConcluído
🇺🇸 Estados Unidos
NCT00000130 · Endophthalmitis Vitrectomy Study (EVS)Concluído
PHASE3
NCT05162625 · Safety and Efficacy of Topical Moxifloxacin for Prevention o…UNKNOWN
PHASE2🇧🇷 Brasil
NCT05079854 · Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Glo…UNKNOWN
PHASE4🇧🇷 Brasil
NCT03812640 · Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract…UNKNOWN
NA🇧🇷 Brasil
NCT06624384 · Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitg…UNKNOWN
PHASE1Iran
NCT06268561 · Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 Mo…UNKNOWN
🇫🇷 França
NCT03968341 · Study of Intraocular Concentrations (Aqueous Humor, Vitreous…UNKNOWN
NA🇫🇷 França
NCT04035369 · Endophthalmitis Post Intravitreal InjectionsUNKNOWN
NA🇨🇦 Canadá
NCT04212429 · The Clinical Safety of Levofloxacin 1.5% vs Topical Moxiflox…UNKNOWN
PHASE1, PHASE2Malaysia
NCT04214821 · The Pharmacokinetics of Topical Levofloxacin 1.5% vs Topical…UNKNOWN
PHASE1, PHASE2Malaysia
NCT04075669 · Multiplex Strip Polymerase Chain Reaction for Diagnosis of E…UNKNOWN
Indonesia
NCT04212078 · Intracameral Levofloxacin (0.5%) vs Intracameral CefuroximeUNKNOWN
PHASE1, PHASE2Malaysia
NCT03677700 · Evaluation of Inflammation of the Anterior Segment by Laser …UNKNOWN
NCT03420820 · Concentrating on Antisepsis: 5% vs. 10% Povidone-Iodine Prio…UNKNOWN
NA
NCT02810587 · Endophthalmitis After Intravitreous Anti-VEGF Injections in …UNKNOWN
Thailand
NCT02324166 · Cefazolin-Lidocaine Combination Solution to Reduce Antibioti…UNKNOWN
PHASE4
NCT02850653 · Targeted PCR and Acute EndophthalmitisUNKNOWN
NA🇫🇷 França
NCT02590523 · Intracameral Antibiotic Safety StudySUSPENDED
PHASE3🇺🇸 Estados Unidos
NCT02770729 · Evaluation of Efficacy and Safety of Intracameral Moxifloxac…Encerrado
PHASE3🇧🇷 Brasil
NCT00431028 · Sub-Tenon's Injection of Triamcinolone and Ciprofloxacin in …Encerrado
PHASE1, PHASE2🇧🇷 Brasil
NCT01496794 · Endophthalmitis CulturesEncerrado
🇺🇸 Estados Unidos
NCT00824811 · Topical Cyclosporine vs. Placebo for Epiphora Associated Wit…Cancelado
PHASE2
NCT00335231 · Preoperative Topical Gatifloxacin on Anterior Chamber Cultur…Cancelado
NA🇨🇦 Canadá
NCT02309736 · OTX-14-002: Device Exposure RegistryCancelado
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
4.821 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 4.821

#1

Advances in the application of metal-organic frameworks in ophthalmology.

Biomaterials science2026 Mar 24

Este artigo destaca que as barreiras fisiológicas dos olhos dificultam a entrega eficaz de medicamentos para doenças oculares graves, como a endoftalmite bacteriana, resultando em tratamentos desafiadores para pacientes e médicos. Os Metal-Organic Frameworks (MOFs) surgem como uma nova classe de materiais porosos promissores, funcionando como carreadores inteligentes de fármacos. Eles têm o potencial de otimizar a ação dos medicamentos, melhorar a eficácia do tratamento para diversas condições oculares e, possivelmente, reduzir a frequência de administração, trazendo avanços significativos para a prática clínica.

🇧🇷 traduzido
#2

Intracameral Antibiotic Selection in Patients With an Allergy History: One Size Does Not Fit All.

JAMA ophthalmology2026 Mar 19

Este artigo ressalta a importância crucial da seleção individualizada de antibióticos intracamerais para prevenir a endoftalmite após cirurgia de catarata. Ele enfatiza que uma abordagem "tamanho único" não é adequada, especialmente para pacientes com histórico de alergias a medicamentos. Para médicos e pacientes, isso significa que a escolha do antibiótico deve ser personalizada para garantir a máxima segurança e eficácia, evitando reações adversas e otimizando a proteção contra infecções.

🇧🇷 traduzido
#3

Chitosan-Coated Silver-Vancomycin Nanoparticles for Treatment of Bacterial Endophthalmitis.

Investigative ophthalmology & visual science2026 Mar 02

Este estudo desenvolveu nanopartículas inovadoras de prata e vancomicina, revestidas com quitosana, como uma promissora estratégia para tratar a endoftalmite bacteriana, especialmente contra patógenos resistentes a medicamentos como o MRSA. As nanopartículas demonstraram alta eficácia em reduzir a infecção, a inflamação e o dano à retina em modelos de doença, com baixa toxicidade para as células oculares. Para pacientes e médicos, isso representa um avanço significativo no combate às infecções oculares graves e resistentes, oferecendo uma nova opção terapêutica que pode melhorar os resultados visuais e preservar a saúde ocular.

🇧🇷 traduzido
#4

Spillover of pseudorabies virus variants to humans: an urgent call for pseudorabies eradication in domestic pigs.

The Lancet. Microbe2026 Feb 24

O vírus da pseudoraiva (PRV), antes considerado exclusivo de porcos, emergiu como um agente zoonótico grave, causando infecções humanas como encefalite (inflamação cerebral) e endoftalmite (inflamação ocular), frequentemente fatais ou com sequelas graves. Desde 2017, novas variantes do vírus na China levaram a dezenas de casos confirmados com alta mortalidade e deficiência, tornando crucial para médicos e pacientes o conhecimento dessa nova ameaça. Para controlar essa preocupação de saúde pública, a erradicação do PRV em porcos domésticos, através de vacinação e biosegurança, é considerada uma medida urgente e essencial.

🇧🇷 traduzido
#5

Hypotony after 25-gauge pars plana vitrectomy with suturing all sclerotomies.

PloS one2026

Este estudo sobre a vitrectomia pars plana 25G com sutura de todas as esclerotomias revelou uma baixa incidência de hipotonia pós-operatória (4,8%), mas, crucialmente, nenhum paciente apresentou sinais clínicos graves como endoftalmite, maculopatia ou descolamento de coroide. Para médicos, é relevante que reoperações aumentam o risco de hipotonia, enquanto o uso de gás SF6 como tamponamento o reduz significativamente, sugerindo um perfil de segurança favorável para a técnica com sutura.

🇧🇷 traduzido

Publicações recentes

Ver todas no PubMed

📚 EuropePMC6.230 artigos no totalmostrando 188

2026

POSTENDOPHTHALMITIS "BUCKET HANDLE SIGN" SIGNIFIES BULLOUS INTERNAL LIMITING LAMINA SEPARATION.

Retina (Philadelphia, Pa.)
2026

Advances in the application of metal-organic frameworks in ophthalmology.

Biomaterials science
2026

A triamcinolone acetonide palmitate nanoemulsion eye drop delivered by iontophoresis for the management of posterior uveitis.

International journal of pharmaceutics
2026

Safety and efficacy of echinocandin antifungal agents in Candida albicans endophthalmitis.

Antimicrobial agents and chemotherapy
2026

Cohort Validation of the Endophthalmitis Vitrectomy Study for Generalized Etiologies.

Clinical ophthalmology (Auckland, N.Z.)
2026

Case Report: Maculopathy following standard dose intracameral cefuroxime injection during ICL surgery.

Frontiers in ophthalmology
2026

Candida pelliculosa cluster endophthalmitis: clinical profile and surgical outcomes in twelve eyes.

International ophthalmology
2026

Efficacy and safety of intraocular lens removal combined with vitrectomy for acute endophthalmitis in pseudophakic eyes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2026

Clostridium perfringens infection following open globe injury due to firecracker blast: A rare case report from Southern India.

IDCases
2026

Optimized polymeric micellar In situ gel formulation incorporating luliconazole for targeted management of fungal endophthalmitis: In vitro characterization, ex vivo ocular permeation, and in vivo ocular irritation evaluation.

Experimental eye research
2026

Intracameral Antibiotic Selection in Patients With an Allergy History: One Size Does Not Fit All.

JAMA ophthalmology
2026

[Ciliary body medulloepithelioma associated with fungal endophthalmitis (clinical observation)].

Vestnik oftalmologii
2026

Surgical Outcomes of Cataract Surgery Following Rapid Glycemic Control During Preoperative Period.

Clinical ophthalmology (Auckland, N.Z.)
2026

Immediate Versus Delayed Sequential Bilateral Cataract Surgery: A Systematic Review.

Clinical ophthalmology (Auckland, N.Z.)
2026

Acute postoperative complications after scleral fixation of Akreos AO60 intraocular lens.

Journal of surgical case reports
2026

Association of Low Vitamin D with Infectious and Non-Infectious Inflammatory Ocular Disease.

Ocular immunology and inflammation
2026

Therapeutic Penetrating Keratoplasty for Aspergillus Fungal Keratitis: A Case Report.

Cureus
2026

Ocular adverse events associated with aflibercept and faricimab: a population-based pharmacovigilance study.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2026

Dosing interval optimization and persistence with faricimab in age-related macular degeneration: An observational study in real-world clinical practice.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria
2026

Areas of uncertainty in endophthalmitis care.

World journal of clinical cases
2026

Real-world treatment patterns and visual outcomes of faricimab in patients with neovascular age-related macular degeneration in the UK at 12 months: the FARWIDE-nAMD study.

Eye (London, England)
2026

Chitosan-Coated Silver-Vancomycin Nanoparticles for Treatment of Bacterial Endophthalmitis.

Investigative ophthalmology & visual science
2026

Silicone Oil Migration During Intravitreal Anti-VEGF Injections: A Review of Clinical Evidence and Factors Related to Transmission.

Retina (Philadelphia, Pa.)
2026

The Role of Prophylactic Topical Administration of Antibiotics in Uncomplicated Cataract Surgery in the Era of Intracameral Antibiotics.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti
2026

Long axial length is a risk factor for infectious endophthalmitis in micro-incisional vitrectomy and membrane peeling surgery.

Retina (Philadelphia, Pa.)
2026

Cost-Utility Analysis of Faricimab Versus Aflibercept in Treating Neovascular Age-Related Macular Degeneration (nAMD) in the United States.

PharmacoEconomics - open
2025

Visual Outcomes of Early Intravitreal Antibiotics and Factors Affecting Presumed Acute Endophthalmitis Post Cataract Surgery in Tertiary Eye Hospital: An Observational Study.

JNMA; journal of the Nepal Medical Association
2026

Perioperative treatments and endophthalmitis after cataract surgery in France: the national population-based ICCARE study.

Scientific reports
2026

Efficacy of Ophthalmic Viscosurgical Device-Assisted Vitrectomy for Membrane Removal in Patients With Complex Proliferative Diabetic Retinopathy.

Journal of ophthalmology
2026

Acute Retinal Detachment Following Ozurdex Implant in a Nonvitrectomized Eye.

Case reports in ophthalmological medicine
2026

Comparison of Clinical Outcomes of Intravitreal 0.625% Povidone-Iodine Versus Antibiotic Injection for Postoperative Endophthalmitis.

Korean journal of ophthalmology : KJO
2026

Clinical Features Associated with Poor Prognosis in Endogenous Endophthalmitis: New Insights from a 5-Year Retrospective Study.

Ocular immunology and inflammation
2026

Spillover of pseudorabies virus variants to humans: an urgent call for pseudorabies eradication in domestic pigs.

The Lancet. Microbe
2026

From kidney to eye: The devastating consequences of delayed diagnosis.

Urology case reports
2026

Genomic and Clinical Profile of Hypervirulent Klebsiella pneumoniae (ST23-K1) Liver Abscesses: Experience with Patients at a Romanian University Hospital.

Pathogens (Basel, Switzerland)
2026

Incidence of post-traumatic endophthalmitis following repaired open globe injury: impact of prophylactic intracameral moxifloxacin.

Eye (London, England)
2026

Atypical acute inflammatory reaction after intravitreal dexamethasone implant: a case of sterile endophthalmitis.

Archivos de la Sociedad Espanola de Oftalmologia
2026

Novel Visible-Light Curable Hydrogel for Closure of Sclerotomy Wounds in Pars Plana Vitrectomy.

Journal of vitreoretinal diseases
2026

Bridging Gaps in Fungal Keratitis Management: Novel Diagnostics, Drug Delivery Systems, and Gene Therapies.

AAPS PharmSciTech
2026

Clinical Characteristics and Prognostic Factors for Visual Outcome in Intraocular Foreign Body Cases Treated at a Tertiary Eye Hospital in Indonesia.

Clinical ophthalmology (Auckland, N.Z.)
2026

Comparative incidence of endophthalmitis after intravitreal dexamethasone implant versus anti-VEGF injections: a retrospective study.

International journal of retina and vitreous
2026

Comparison of different antibiotic prophylaxis regimens for the prevention of endophthalmitis after penetrating keratoplasty.

International ophthalmology
2026

A second occurrence of intravitreal injection-associated endophthalmitis 2 years apart.

American journal of ophthalmology case reports
2026

Correlation between blood glucose levels and endophthalmitis risk after intravitreal injections of anti-vascular endothelial growth factor.

Eye (London, England)
2026

Long Term Outcomes After Implantation of Sutureless Intrascleral Fixation Lenses Following Complicated Cataract Surgery - A Single Center Retrospective Study.

Retina (Philadelphia, Pa.)
2026

ENDOPHTHALMITIS INCIDENCE AFTER VITRECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RISK FACTORS AND PREVENTION STRATEGY.

Retina (Philadelphia, Pa.)
2026

Retinal detachment following endogenous endophthalmitis: a multicenter study.

Retina (Philadelphia, Pa.)
2026

Repurposing of Near-Infrared IR 808: A Promising Agent for the Treatment of Gram-Positive Bacteria Induced Endophthalmitis.

ACS applied bio materials
2026

Ocular inflammation after intraocular drug delivery: Mechanisms, risk factors, and implications for clinical practice.

Survey of ophthalmology
2026

A comprehensive review of resistome profiles in ocular pathogens: Insights into Pseudomonas aeruginosa and emerging resistance trends.

Journal of infection and public health
2026

Secondary orbital abscess from hypervirulent Klebsiella pneumoniae panophthalmitis with scleral necrosis.

Orbit (Amsterdam, Netherlands)
2026

MAGNETIC INTRAOCULAR FOREIGN BODY INJURIES: INTRAVITREAL ANTIBIOTIC PROPHYLAXIS, ENDOPHTHALMITIS RISK AND PROGNOSTIC FACTORS.

Retina (Philadelphia, Pa.)
2026

Endogenous Nocardia Nova Panophthalmitis Masquerading as Malignancy: A Clinicopathologic Report.

Retinal cases & brief reports
2026

Endogenous Versus Exogenous Candida Endophthalmitis: Clinical Features, Risk Factors, Treatment Modalities, and Visual Outcomes.

American journal of ophthalmology
2026

Subconjunctival povidone-iodine in the treatment of bleb-associated endophthalmitis.

Retinal cases & brief reports
2026

Ophthalmologic Evaluation and Clinical Outcome in Candidemia: A 7-Year Retrospective Multicenter Cohort Study.

Open forum infectious diseases
2026

Multidrug-resistant Staphylococcus hominis endophthalmitis after cataract surgery: A case report.

IDCases
2026

Mihe (MIOK) KPro with auricular cartilage reinforcement in end-stage corneal blindness: An open-label, nonrandomized trial.

Advances in ophthalmology practice and research
2026

Hypotony after 25-gauge pars plana vitrectomy with suturing all sclerotomies.

PloS one
2026

Non-physician delivered intravitreal injection service: A systematic review of safety, implementation, training and patient experience.

Acta ophthalmologica
2026

Laboratory Workup in Pars Plana Diagnostic Vitrectomy: A Real-World Multidisciplinary Retrospective Case Series of Brazilian Patients with Uveitis.

Ocular immunology and inflammation
2026

Delayed-Onset Endophthalmitis Associated With Glaucoma Drainage Implant.

American journal of ophthalmology
2026

Atypical Panuveitis in Disseminated Coccidioidomycosis.

Retinal cases & brief reports
2026

Endophthalmitis After Dexamethasone Implant.

Clinical & experimental ophthalmology
2026

Fulminant Bilateral Streptococcus pneumoniae Endophthalmitis in a Kidney Transplant Patient With Prior Herpetic Keratopathy.

Cureus
2026

Integrated analysis of risk factors, visual prognosis, and pathogens in pediatric post-traumatic endophthalmitis: a retrospective cohort study.

Frontiers in medicine
2026

Clinical features and treatment outcomes of acute-onset endophthalmitis caused by Staphylococcus lugdunensis: a case series.

Journal of ophthalmic inflammation and infection
2026

Failure of Endophthalmitis Prophylaxis: A Laboratory Model Comparing Antibiotics and Bacterial Loads.

Journal of cataract and refractive surgery
2026

Bilateral Nocardia farcinica Chorioretinitis With Endogenous Endophthalmitis and Concurrent CNS Disease: A Case Report.

Cureus
2026

Efficacy of Intravitreal Caspofungin in a Case of Bilateral Candida albicans Endophthalmitis.

Journal of vitreoretinal diseases
2026

Delayed Scleral Buckle Removal in Cases of Exposure, Extrusion, and Infection: Clinical Features, Microbiologic Aspects, and Clinical Outcomes.

Journal of vitreoretinal diseases
2026

From Gut to Globe: Endogenous Endophthalmitis as a Sentinel Sign of Polymicrobial Intra-Abdominal Infection.

Clinical case reports
2026

Intraocular infection of Moraxella nonliquefaciens accompanied by secondary angle-closure glaucoma: A case report.

The Journal of international medical research
2026

Endogenous group A streptococcal endophthalmitis mimicking uveitis in a healthy 3-year-old: case report and literature review.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
2026

Three-Dimensional Digital Visualization System-Assisted Vitrectomy for Infectious Endophthalmitis.

Journal of ophthalmology
2026

Comparative Epidemiology and Treatment Patterns of Acute Postoperative and Endogenous Endophthalmitis in South Korea.

Ophthalmic epidemiology
2025

Emerging Ocular Pathogen Resistance and Clinically Used Solutions: A Problem That Is More than Meets the Eye.

Pharmaceuticals (Basel, Switzerland)
2025

Intracameral moxifloxacin for endophthalmitis prophylaxis after cataract surgery: a systematic review and meta-analysis.

Frontiers in medicine
2026

Intraocular Inflammation After Intravitreal Faricimab Injections: A Case Series.

Clinical & experimental ophthalmology
2025

Ocular injuries and the most common acute conditions in ophthalmology.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti
2025

Management of Bilateral Endogenous Methicillin-Sensitive Staphylococcus aureus (MSSA) Endophthalmitis Without Intravitreal Sampling or Injection.

Cureus
2026

Visual prognosis following open globe injury: clinical characteristics and risk factors from Vietnam National Eye Hospital.

International journal of ophthalmology
2026

Echogenic Diagnosis of Bilateral Subretinal Abscesses in a Patient with Group B Streptococcus Endogenous Endophthalmitis.

Retinal cases & brief reports
2026

Actinomyces sp. detected by next-generation sequencing in paraffin-embedded, formalin-fixed tissues of a dog with severe panophthalmitis and periocular cellulitis.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2026

Adjunctive tacrolimus in the treatment of fungal keratitis requiring therapeutic penetrating keratoplasty.

American journal of ophthalmology case reports
2026

Endogenous endophthalmitis secondary to subclinical pyelonephritis.

Journal of hospital medicine
2026

Intravitreal Gene Therapy with LX102-C01 in Neovascular Age-Related Macular Degeneration: A Phase I Dose-Escalation Study of 12-Month Safety and Efficacy Outcomes.

Ophthalmology science
2025

Purpureocillium lilacinum Keratitis and Endophthalmitis in an Aphakic Eye With Secondary Glaucoma: A Case Report.

Cureus
2026

Silicone Punctal Plugs as a Significant Risk Factor for Iatrogenic Endophthalmitis: A Case Report.

Ocular immunology and inflammation
2026

Substance Use Disorder Interventions and Ophthalmic Outcomes for Injection Drug Use-Associated Endogenous Endophthalmitis.

Ophthalmology. Retina
2026

Long-term surgical outcomes of primary silicone orbital implant after orbital evisceration in infectious versus non-infectious cases.

European journal of ophthalmology
2026

Endoscope-Assisted Vitrectomy for Bleb-Related Endophthalmitis: A Case Series.

Retinal cases & brief reports
2025

Successful Repair of Glaucoma Drainage Device Tube Exposure With a Corneal Patch Graft and Double-Layer Amniotic Membrane: A Case Report.

Cureus
2025

Ocular decompression retinopathy after anterior chamber paracentesis - Case series and systematic review.

Taiwan journal of ophthalmology
2025

Posterior capsular rent - Prevention, recognition, and management - A review.

Taiwan journal of ophthalmology
2026

Endogenous endophthalmitis secondary to neisseria meningitidis: a case report.

BMC ophthalmology
2026

Unexplained long-term increase in intraocular pressure during the treatment of macular disease with intravitreal anti-VEGF.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2026

An injectable dual-drug-loaded hydrogel for the treatment of bacterial endophthalmitis.

Biomaterials advances
2026

Multimodal imaging in subretinal hypopyon endogenous endophthalmitis: Early detection of retinal tear and detachment.

Retinal cases & brief reports
2026

Fulminant Clostridium septicum Endogenous Endophthalmitis Presenting with Intraocular Gas in a Patient with Metastatic Endometrial Cancer.

Retinal cases & brief reports
2026

Impact of Candida Care Bundle Compliance on the Prognosis of Patients With Candidemia: A Multicenter Retrospective Cohort Study With Propensity Score Matching Analysis (2016-2023).

Open forum infectious diseases
2025

[Comparison of the efficacy of trabeculectomy combined with Schlemm canal incision versus trabeculectomy alone in the treatment of primary open angle glaucoma].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2026

[Etiological characteristics, clinical manifestations, and prognosis of patients with endogenous endophthalmitis in 2024: a single-center retrospective cohort study].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2025

Recurrent sterile endophthalmitis following intravitreal Faricimab: A case report.

Retinal cases & brief reports
2026

Repeat Intraocular Sampling and Microbiological Testing in Infectious Endophthalmitis: Comment.

Clinical & experimental ophthalmology
2026

How does hypervirulent Klebsiella pneumoniae influence the risk and visual outcomes of endogenous endophthalmitis in Klebsiella pneumoniae pyogenic liver abscess? A systematic review and meta analysis.

Journal of infection and public health
2025

Intraocular Povidone-Iodine During Pars Plana Vitrectomy for Severe and Atypical Endophthalmitis.

Retina (Philadelphia, Pa.)
2025

Long-Term Outcomes of 4-Point Expanded Polytetrafluoroethylene and 2-Point Polypropylene Fixation of Scleral-Sutured Intraocular Lenses.

Journal of vitreoretinal diseases
2025

Scedosporium apiospermum as a Causative Organism of Chronic Endophthalmitis Following Uncomplicated Cataract Surgery.

Journal of vitreoretinal diseases
2025

Incidence and Microbiology of Endophthalmitis in Eyes With a Type 1 Boston Keratoprosthesis: A Systematic Review and Meta-Analysis.

Cornea
2025

Antibiotics in Tactical Combat Casualty Care 2025: TCCC Change 25-1.

Journal of special operations medicine : a peer reviewed journal for SOF medical professionals
2025

From pathogen to prognosis: microbial keratitis spectrum and treatment outcomes in a 5-Year tertiary center experience.

Journal of ophthalmic inflammation and infection
2025

Country-Specific Approaches to Preventing Infections in Cataract Surgery.

Antibiotics (Basel, Switzerland)
2025

Consecutive presumed endogenous candida endophthalmitis and presumed cytomegalovirus uveitis in an immunocompromised patient: a case report.

Journal of medical case reports
2026

Explosive Weapons Trauma Care Collective (EXTRACCT) Blast Injury Clinical Practice Guideline: Ocular Trauma.

World journal of surgery
2025

Bilateral Sterile Intraocular Inflammation Following Intravitreal Aflibercept 8 mg Injections: A Case Report.

Reports (MDPI)
2025

Enhanced surgical outcomes in refractory glaucoma: a retrospective study of using adjustable sutures with Ex-PRESS filtration device.

Frontiers in medicine
2026

Current Management Strategies for Hypervirulent Klebsiella.

Infectious disease clinics of North America
2026

Bilateral sequential endogenous endophthalmitis due to Streptococcus pyogenes: case report and literature review.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2025

Bilateral endogenous endophthalmitis from asymptomatic Aspergillus niger fungal infective endocarditis in the immunosuppressed patient: A case report.

Medicine
2025

Post-strabismus surgery endophthalmitis without evident scleral perforation due to Haemophilus influenzae in a pediatric patient with neurofibromatosis type 1.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
2026

Incidence and clinical characteristics of acute infectious endophthalmitis after approximately 2.03 million cataract surgeries in China over a 5-year period (2017-2021).

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2026

New evidence for effectiveness of intracameral moxifloxacin for postcataract surgery endophthalmitis prophylaxis.

Journal of cataract and refractive surgery
2026

The association between treatment method, microbiological findings, and visual acuity in endophthalmitis patients: A retrospective, multi-centred study.

Eye (London, England)
2025

CARD9 Mutations in Patients with Invasive Fungal Infections.

Mycopathologia
2025

Post-Cataract Surgery Endophthalmitis Prophylaxis Survey in Thai Ophthalmologists.

Clinical ophthalmology (Auckland, N.Z.)
2026

β-D-glucan in Intraocular Fluids for Fungal Endophthalmitis: A Meta-Analysis of Diagnostic Test Accuracy.

Ocular immunology and inflammation
2025

Role of Sanger Sequencing in the Early Diagnosis of Infective Endophthalmitis: Experience From a Pilot Study.

Cureus
2026

In vitro silicone oil emulsification in retinal detachment treatment: Methods, designs, and future strategies.

Acta biomaterialia
2025

The full-filling air technique: A case series of modified DSAEK in vitrectomized eyes without stable compartmentalization.

European journal of ophthalmology
2025

Intraocular Cytokine Level Prediction from Fundus Images and Optical Coherence Tomography.

Sensors (Basel, Switzerland)
2025

When should we declare an endophthalmitis outbreak? A Poisson model of post-cataract surgery endophthalmitis outbreak projections.

Journal of cataract and refractive surgery
2025

Outcomes of Baerveldt implantation for pediatric glaucoma following surgery: a systematic review and meta-analysis.

International ophthalmology
2025

Role of Multimodal Imaging in the Diagnosis and Management of Endogenous Candida Endophthalmitis in a neonate with Aggressive Retinopathy of Prematurity.

Retinal cases & brief reports
2025

Clinical Characteristics, Complications, and Outcomes of Hypervirulent Klebsiella pneumoniae Liver Abscess: A Systematic Review of 53 Cases.

Cureus
2025

Intraocular inflammation following aflibercept 8 mg: real-world data from a multicentre retrospective observational study.

International journal of retina and vitreous
2025

Advances in nanomedicine-based retinal drug delivery: mechanisms and translational applications.

Journal of nanobiotechnology
2026

ANTIBIOTIC PROPHYLAXIS FOR PREVENTING ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTIONS: An Updated Systematic Review and Meta-analysis.

Retina (Philadelphia, Pa.)
2026

Tolerability of 0.5% Liposomal Ozonated Oil Versus 0.6% Povidone-Iodine in Antiseptic Prophylaxis for Intravitreal Injections.

Ophthalmology and therapy
2026

Comparative Outcomes of Endophthalmitis in Trabeculectomy and Tube Shunt Surgery: A Nine-Year Review of Clinical Course and Management.

Ocular immunology and inflammation
2025

Phacogenic uveitis masquerading as endophthalmitis.

BMJ case reports
2025

Eying up predatory bacteria: living antimicrobials for ocular infections.

Current opinion in ophthalmology
2025

Flutter Sign - An Indicator of Intact Anterior Hyaloid Face After Posterior Capsule Rupture During Phacoemulsification.

Clinical ophthalmology (Auckland, N.Z.)
2025

Endophthalmitis with keratitis-how to manage severe cases? : A narrative review.

Die Ophthalmologie
2026

Major Complications following Strabismus Surgery: Nine-year Data from the IRIS® Registry.

Ophthalmology
2026

Pathogen-Associated Visual Outcomes Following Postprocedure Endophthalmitis.

American journal of ophthalmology
2025

Clinical Features and Outcomes of Fishing-Related Ocular Injuries.

Journal of vitreoretinal diseases
2025

Formulation of α-Linolenic Acid-Based Microemulsions for Age-Related Macular Degeneration: Physicochemical Tests and HET-CAM Assays for Anti-Angiogenic Activities.

Medicina (Kaunas, Lithuania)
2025

Mechanisms and Evolution of Antimicrobial Resistance in Ophthalmology: Surveillance, Clinical Implications, and Future Therapies.

Antibiotics (Basel, Switzerland)
2025

[Transient maculopathy after intracameral injection of cefuroxime].

Die Ophthalmologie
2025

Aggressive Purpureocillium lilacinum Kerato-Endophthalmitis in a Diabetic Contact Lens Wearer Culminating in Enucleation: A Case Report and Review of the Literature.

Journal of fungi (Basel, Switzerland)
2025

Burkholderia cenocepacia Keratitis With Exogenous Endopthalmitis: A Complex Combination.

Cureus
2025

A rare case of exogenous fungal endophthalmitis following a traumatic corneal insult.

BMC ophthalmology
2025

Cefuroxime-related hemorrhagic retinal vasculitis following cataract surgery.

BMC ophthalmology
2025

Bilateral endogenous fungal endophthalmitis following elective surgical abortion: a single center case series.

Journal of ophthalmic inflammation and infection
2025

Pyogranulomatous endophthalmitis and posterior uveitis in a crested capuchin (Sapajus robustus) with systemic Paracoccidioides brasiliensis infection.

Veterinary research communications
2026

Incidence of toxic anterior segment syndrome and endophthalmitis in 190 000 eyes in a high-volume, multisurgeon, national network of ambulatory surgical centers using uniform perioperative protocols.

Journal of cataract and refractive surgery
2025

Long-term effectiveness of the trabecular micro-bypass (iStent): 3-year real world data in glaucoma and ocular hypertension.

International ophthalmology
2025

Acute endogenous endophthalmitis caused by Streptococcus agalactiae: A case report and review.

IDCases
2025

Novel Needle for Intravitreal Injections Does Not Affect Biological Activity of Anti-VEGF Drugs.

Clinical ophthalmology (Auckland, N.Z.)
2026

Advanced Drug Delivery Systems for Age-Related Macular Degeneration Treatment: Latest Trends and Future Prospects.

Advanced healthcare materials
2025

The Role of in Vivo Confocal Microscopy in Diagnosing and Managing Infectious Keratitis in Deployed French Military Personnel: A Case Series.

Military medicine
2025

Klebsiella pneumoniae Endogenous Endophthalmitis in an Active Duty Service Member.

Military medicine
2025

Enduring Threats of Infectious Disease in Large-Scale Combat Operations: Lessons from a Case of Klebsiella pneumoniae Endogenous Endophthalmitis.

Military medicine
2025

Unusual presentation of fungal keratitis and endogenous endophthalmitis in Sézary syndrome: a case report.

American journal of ophthalmology case reports
2026

Endogenous endophthalmitis in a tertiary referral centre: a 14-year case series with comparative perspective.

Eye (London, England)
2025

Endogenous Nocardia farcinica Endophthalmitis in Chronic Lymphocytic Leukemia: A Case Report and Literature Review.

Retinal cases & brief reports
2025

Aspergillus endophthalmitis early post-phacoemulsification: a case of failed salvage.

International ophthalmology
2026

When the Keratoprosthesis Is Too Small: Homburger Corneal Gap Bridging Surgical Technique for Combined Vitreoretinal Surgery and Large-Diameter Keratoplasty.

Cornea
2025

Multisite infection with Austrian syndrome caused by non-vaccine pneumococcal serotype-case report.

ASM case reports
2025

Epidemiology, Clinical Features, and Visual Outcomes After Intraocular Foreign Body Removal: An IRIS® Registry Analysis.

Ophthalmology. Retina
2026

Treatment patterns and long-term outcomes in anti-VEGF-treated macular oedema secondary to retinal vein occlusion: a retrospective observational study.

Eye (London, England)
2025

Endogenous endophthalmitis complicating infective endocarditis: a multicentre case-matched control cohort.

European heart journal open
2025

Case Report: An endogenous endophthalmitis case caused by Haemophilus influenzae.

Frontiers in medicine
2025

Toxic Anterior Segment Syndrome Following Implantable Collamer Lens Implantation in a Patient With Keratoconus and Nystagmus: A Case Report.

Cureus
2025

Visual and Anatomical Outcomes of Microbial Keratitis-Induced Endophthalmitis.

Ocular immunology and inflammation
2025

Simultaneous bilateral intravitreal anti-vascular endothelial growth factor injections from one vial for diabetic macular edema: a retrospective analysis.

Frontiers in medicine
2025

Topical Povidone Iodine 2.5% Versus 5% for Endophthalmitis Prophylaxis During Intravitreal Injections.

Journal of ophthalmology
2025

Ocular manifestations of vaccine-preventable diseases: A comprehensive review.

Vaccine
2025

A case of panophthalmitis with orbital infection of polymicrobial origin.

BMC infectious diseases
2026

Endogenous endophthalmitis: a nine-year retrospective study of 33 patients.

Eye (London, England)
2025

Comparative Analysis of Ocular Adverse Events between Aflibercept 8 mg and Faricimab: A Global Population-Based Study across 65 Countries.

Ophthalmology. Retina
2025

Comparative efficacy of intravitreal aflibercept biosimilar QL1207 versus reference aflibercept in the treatment of diabetic macular edema.

Frontiers in medicine
2025

A Rare Case of Disseminated Group G Streptococcus Bacteremia Complicated by Multi-Systemic Infections: Infective Endocarditis, Endophthalmitis, and Meningitis.

The American journal of case reports
2025

A Case Series of Serious Adverse Events Following Anti-VEGF Intravitreal Injections.

Romanian journal of ophthalmology
2025

Panophthalmitis in a case of Glanzmann thrombasthenia - The dilemma in diagnosis.

Romanian journal of ophthalmology
2025

A rare case of fungal endophthalmitis caused by an entomopathogen.

BMC ophthalmology
2025

From 1995 to now: the endophthalmitis vitrectomy study and the need for a contemporary evidence base.

Eye (London, England)
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Respostas geradas por IA a partir das fontes citadas

A endoftalmite é uma infecção que atinge as estruturas internas do olho. Trata-se de uma condição catalogada pelo código internacional CID-10 H44.0.

Referências

Fontes citadas no texto, publicações do grafo e bases de dados usadas neste verbete

10 publicações do grafo RarasNet (PubMed) · 6 bases de dados. Títulos, periódicos e PMIDs vêm direto da fonte, sem intermediação de IA.

  1. ORPHA:199323
    Orphanet
  2. GARD:20333
    GARD (NIH)
  3. Q1294912
    Wikidata

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Citar este verbete

Raras. (s.d.). Endoftalmite. Em Raras — Enciclopédia de Doenças Raras do Brasil. https://raras.org/doenca/endoftalmite

Formato APA. Conteúdo sob CC BY 4.0 — reuso livre com atribuição.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Endoftalmite
Compêndio · Raras BR

Endoftalmite

ORPHA:199323 · MONDO:0016047
CID-10
H44.0 · Endoftalmite purulenta
CID-11
Ensaios
8 ativos
Medicamentos
3 registrados
MedGen
UMLS
C0014236
EuropePMC
Wikidata
Wikipedia
Papers 10a

📋 Origem dos dados

Esta página agrega dados de fontes públicas e oficiais. Dados sobre cobertura no SUS (PCDT, CEAF) são verificados ativamente por agente proativo (ver badge no infobox). Demais dados têm atribuição de fonte + data da última sincronização — clique para abrir o original.

Doença rara (ontologia)
fonte: Orphanet
Identificador unificado
fonte: MONDO
Indexação biomédica
fonte: MeSH (NLM)
Dado público estruturado
fonte: Wikidata
Moléculas estudadas na doença
fonte: OpenTargets
Rara