Raras
Buscar doenças, sintomas, genes...
Cefalalgia autonômica do trigêmeo
ORPHA:157843CID-11 · 8A82DOENÇA RARA

Cefaléia caracterizada por episódios de dor unilateral de curta duração e sintomas autonômicos cranianos ipsilaterais associados.

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Introdução

O que você precisa saber de cara

📋

Cefaléia caracterizada por episódios de dor unilateral de curta duração e sintomas autonômicos cranianos ipsilaterais associados.

Pesquisas ativas
7 ensaios
119 total registrados no ClinicalTrials.gov
Publicações científicas
208 artigos
Último publicado: 2026 Apr
🏥
SUS: Sem cobertura SUSScore: 0%
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

👁️
Olhos
3 sintomas
🫃
Digestivo
3 sintomas
😀
Face
3 sintomas
👂
Ouvidos
2 sintomas
📏
Crescimento
1 sintomas

+ 24 sintomas em outras categorias

Características mais comuns

Dor de ouvido
Rinite
Miose
Pescoço rígido
Edema palpebral
Fotofobia
36sintomas
Sem dados (36)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 36 características clínicas mais associadas, ordenadas por frequência.

Dor de ouvidoEar pain
RiniteRhinitis
MioseMiosis
Pescoço rígidoStiff neck
Edema palpebralPalpebral edema

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa3desde 2023
Total histórico208PubMed
Últimos 10 anos154publicações
Pico202128 papers
Linha do tempo
2023Hoje · 2026🧪 2002Primeiro ensaio clínico📈 2021Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 22
1Fase 11
·Pré-clínico7
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 10 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Cefalalgia autonômica do trigêmeo

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Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

6 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

119 ensaios clínicos encontrados, 7 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
155 papers (10 anos)
#1

Secondary trigeminal autonomic cephalgia with cavernous sinus involvement: a diagnostic challenge.

BMJ case reports2025 Sep 28

Chronic, side-locked headache refractory to standard treatment warrants investigation for underlying inflammatory, infectious or infiltrative aetiologies. This case highlights a rare presentation of a patient with a chronic history of hemicranial headache who had presented with recent worsening and unresponsiveness to conventional treatment. IgG4-related disease with hypertrophic pachymeningitis (HPM), primarily affects the cavernous sinus and orbital apex, can lead to multiple cranial nerve palsies and mimics secondary trigeminal autonomic cephalalgia. The diagnostic challenge was compounded by concomitant extrapulmonary tuberculosis, a frequent mimic in endemic regions, obscuring the clinical picture. This case underscores the importance of integrating advanced neuroimaging and serological markers for accurate diagnosis. Given the absence of definitive treatment guidelines and high chances of relapses for IgG4-related HPM, it highlights the need for personalised therapeutic strategies and long-term follow-up. This report adds to the limited literature, emphasising the need for heightened clinical suspicion in atypical headache syndromes.

#2

Onset of secondary SUNCT syndrome with concomitant occipital neuralgia after dorsal medullary infarction.

BMJ case reports2025 Mar 28

Short-lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing (SUNCT) syndrome is a rare trigeminal autonomic cephalalgia characterised by brief, unilateral, severe pain episodes and autonomic symptoms. Secondary SUNCT has been associated with brainstem lesions, implicating the trigeminocervical complex in its pathogenesis. We describe a man in his 40s with secondary SUNCT and occipital neuralgia following a right dorsolateral medullary infarction. He presented with right facial numbness and burning pain lasting about a minute, occurring over four times daily, triggered by touch. Examination revealed dacryorrhoea, rhinorrhoea and ipsilateral facial oedema. Brain MRI confirmed subacute medullary infarction, establishing secondary SUNCT. Subsequently, he developed intermittent electrical pain in the right posterior head, neck, shoulder and arm, diagnosed as occipital neuralgia, which responded to gabapentin. This case highlights the importance of high-resolution neuroimaging and follow-up in atypical headache presentations to identify structural lesions and optimise management.

#3

Risk of Attempted and Completed Suicide in Persons Diagnosed With Headache.

JAMA neurology2025 Mar 01

Although past research suggests an association between migraine and attempted suicide, there is limited research regarding risk of attempted and completed suicide across headache disorders. To examine the risk of attempted and completed suicide associated with diagnosis of migraine, tension-type headache, posttraumatic headache, and trigeminal autonomic cephalalgia (TAC). This was a population-based cohort study of Danish citizens from 1995 to 2020. The setting was in Denmark, with a population of 5.6 million people. Persons 15 years and older who were diagnosed with headache were matched by sex and birth year to persons without headache diagnosis with a ratio of 5:1. Data analysis was conducted from May 2023 to May 2024. First-time headache diagnoses identified from inpatient hospitalizations, emergency department visits, and outpatient specialty clinic visits using International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes. Diagnostic codes from the ICD-10 were used to identify attempted suicide from the Danish National Patient Registry and the Danish Psychiatric Central Research Register and completed suicides from the Danish Register of Causes of Death. Absolute risks (ARs) and risk differences (RDs) for attempted and completed suicide were calculated using the cumulative incidence function. Hazard ratios (HRs) for attempted and completed suicide associated with headache diagnosis were computed adjusting for age, sex, year, education, income, baseline comorbidities, and accounting for competing risk of death. In total, 119 486 persons (83 046 female [69.5%]) diagnosed with headache were identified and matched with 597 430 persons (415 230 female [69.5%]) drawn from the general population. Participants' median (IQR) age was 40.1 (29.1-51.6) years. The 15-year AR of attempted suicide among persons diagnosed with headache was 0.78% (95% CI, 0.72%-0.85%) vs 0.33% (95% CI, 0.31%-0.35%) in the comparison cohort (RD, 0.45%; 95% CI, 0.39%-0.53%). The 15-year AR of completed suicide among persons diagnosed with headache was 0.21% (95% CI, 0.17%-0.24%) vs 0.15% (95% CI, 0.13%-0.16%) in the comparison cohort (RD, 0.06%; 95% CI, 0.02%-0.10%). The hazards of attempted suicide (HR, 2.04; 95% CI, 1.84-2.27) and completed suicide (HR, 1.40; 95% CI, 1.17-1.68) were elevated among persons with headache vs comparison cohort members. Findings were consistent across headache types, with stronger associations for TACs and posttraumatic headache. Results of this cohort study revealing the robust and persistent association of headache diagnoses with attempted and completed suicide suggest that behavioral health evaluation and treatment may be important for these patients.

#4

Understanding the Diagnosis of Primary Headaches in Outpatients Referred to Japanese Headache Specialists.

Cureus2025 Dec

Background The timely and accurate diagnosis of primary headaches is crucial for enhancing patients' quality of life. However, primary headaches have been reported to be misdiagnosed and underdiagnosed worldwide, especially by nonspecialists. In Japan, despite the high prevalence of primary headaches, research on the extent of headache misdiagnosis and underdiagnosis remains limited. Therefore, we aimed to assess the rates of concordant primary headache diagnoses between previous physicians and headache specialists among outpatients who were referred to the headache center in Japan. Methodology In this retrospective, observational study, we collected data at the renowned Headache Center of Tominaga Hospital in Japan from August 2024 through April 2025. The target population was headache patients aged six years or older who were referred from or previously visited another medical institution. We classified headache diagnoses into the following five categories: migraine; tension-type headache; trigeminal autonomic cephalalgia; other primary headaches; and other headaches, including secondary headaches and painful cranial neuropathies. We calculated the accuracy rate of previous physicians' diagnoses by comparing theirs with those made by board-certified headache specialists at Tominaga Hospital. Results We analyzed 147 patients (mean age = 41.5 years; SD = 18.0 years) who were referred to Tominaga Hospital for headaches. Of these patients, 47 (32.0%) were male, and 100 (68.0%) were female. Overall, 69 (47.3%) patients were undiagnosed by previous physicians. The overall accuracy rate of previous physicians' diagnoses was 43.8% (95% confidence interval (CI) = 36.0-51.9%). The sensitivity and specificity of migraine were 52.6% (95% CI = 43.5-61.6%) and 78.1% (95% CI = 61.2-89.0%), respectively. Conclusions Approximately half of the patients had not received any specific diagnosis, and fewer than half had diagnoses consistent between headache specialists and previous physicians. These findings highlight the challenges of headache diagnosis and underscore the need for further investigation to enhance diagnostic accuracy.

#5

A case report: Infrazygomatic approach neurocryoablation of the sphenopalatine ganglion under cone beam computer tomography guidance in treating refractory headaches.

Interventional pain medicine2025 Dec

The sphenopalatine ganglion (SPG) drives the cranial autonomic symptoms associated with trigeminal autonomic cephalalgias, migraine, and trigeminal neuralgia. Infrazygomatic approach SPG block serves as the gold standard for both prognostic and therapeutic intervention for management of refractory headache with autonomic symptoms. However, this intervention often provides only short-term relief. Identification of novel interventions that provide more durable relief is imperative. An 84-year-old female with chronic headache featuring autonomic cranial symptoms that failed both medication and conservative intervention management. Patient responded well to infrazygomatic approach SPG block using combined cone beam CT and fluoroscopy guidance, however, experienced fading therapeutic response over the years. Subsequently, patient underwent neurocryoablation of the SPG, from which, satisfactory and sustained improvement of her headache pain was achieved at six month follow up. This is the first case demonstrating the clinical feasibility and therapeutic outcomes of SPG neurocryoablation in treating refractory headaches.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC34 artigos no totalmostrando 154

2025

Understanding the Diagnosis of Primary Headaches in Outpatients Referred to Japanese Headache Specialists.

Cureus
2025

A case report: Infrazygomatic approach neurocryoablation of the sphenopalatine ganglion under cone beam computer tomography guidance in treating refractory headaches.

Interventional pain medicine
2025

A Comprehensive Review of Trigeminal Autonomic Cephalalgias.

Physical medicine and rehabilitation clinics of North America
2025

Secondary trigeminal autonomic cephalgia with cavernous sinus involvement: a diagnostic challenge.

BMJ case reports
2025

Neuromodulation in trigeminal autonomic cephalalgias: 11-year experience of non-invasive vagus nerve stimulation.

Cephalalgia : an international journal of headache
2025

Galcanezumab reduces trigeminal nociception and is effective in preclinical models of migraine and trigeminal autonomic cephalalgias.

Headache
2025

Understanding Delays and Diagnostic Shifts in Primary Headaches: Evidence from Japanese Health Insurance Claims.

Cureus
2025

Recurrent headache mimicking cluster headache: a diagnostic challenge.

Internal and emergency medicine
2025

Onset of secondary SUNCT syndrome with concomitant occipital neuralgia after dorsal medullary infarction.

BMJ case reports
2025

Trigeminal autonomic cephalalgia after common eye surgery: Case series and literature review.

Revue neurologique
2025

Co-morbid Indomethacin-Responsive Headaches in a Woman in Her Late 60s With Paroxysmal Hemicrania and Hypnic Headache: A Case Report.

Cureus
2025

Hemicrania continua with rhinosinusitis: a case report.

Korean journal of family medicine
2025

Risk of Attempted and Completed Suicide in Persons Diagnosed With Headache.

JAMA neurology
2024

German language adaptation of the Cluster Headache Quality of Life Scale (CH-QoL).

BMC neurology
2024

Prophylactic Cyproheptadine to Control Paroxysmal Hemicrania Attacks: A Preliminary Investigation.

Advanced biomedical research
2024

Ultrasound guided pulsed radiofrequency neuromodulation of sphenopalatine ganglion treatment for allergic rhinitis in childern: A case report.

Clinical case reports
2024

Artificial intelligence and headache.

Cephalalgia : an international journal of headache
2024

The critical role of neuroimaging in hemicrania continua: A systematic review and case series.

Headache
2024

Paediatric secondary trigeminal autonomic cephalalgia: While rare, it exists.

Anales de pediatria
2024

Melatonin in hemicrania continua and paroxysmal hemicrania.

Cephalalgia : an international journal of headache
2024

Facial pain in MS: When to think of trigeminal autonomic cephalalgia.

Multiple sclerosis (Houndmills, Basingstoke, England)
2024

SUNCT, SUNA and short-lasting unilateral neuralgiform headache attacks: Debates and an update.

Cephalalgia : an international journal of headache
2024

Primary Headache Is Related to Reduced Health-Related Quality of Life in Children with Epilepsy.

Healthcare (Basel, Switzerland)
2024

Complementary and Integrative Medicine for the Treatment of Trigeminal Neuralgia and Trigeminal Autonomic Cephalalgia.

Current pain and headache reports
2024

Epidemiology and clinical features of paroxysmal hemicrania: A systematic review and meta-analysis.

Headache
2024

Translating the Cluster Headache Quality of Life Questionnaire (CHQ) from English to Dutch with the TRAPD method.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

A state-of-the-art review of functional magnetic resonance imaging technique integrated with advanced statistical modeling and machine learning for primary headache diagnosis.

Frontiers in human neuroscience
2023

Sudden onset headaches in paediatric emergency departments: diagnosis and management.

Italian journal of pediatrics
2023

Reliability of a telephone interview for the classification of headache disorders.

Frontiers in neurology
2023

Case report: Recurrent nocturnal awakenings in cluster headache: a different type of ghost attack.

Frontiers in neurology
2023

European Academy of Neurology guidelines on the treatment of cluster headache.

European journal of neurology
2023

Chronic Unilateral Headache Related to Scar Neuromas.

Journal of medical cases
2023

Deep Brain Stimulation for Chronic Cluster Headaches: A Systematic Review and Meta-Analysis.

Stereotactic and functional neurosurgery
2023

Prevalence and clinical features of hemicrania continua in clinic-based studies: A systematic review and meta-analysis.

Cephalalgia : an international journal of headache
2023

Transnasal endoscopy-guided percutaneous access to the sphenopalatine ganglion for neurostimulation in the treatment of primary headache: operative technique and feasibility.

Brazilian journal of otorhinolaryngology
2022

Characteristics and Gender Differences of Headache in the Veterans Health Administration: A National Cohort Study, Fiscal Year 2008-2019.

Neurology
2022

Headache and Autonomic Dysfunction: a Review.

Current neurology and neuroscience reports
2022

Substance use related cluster headache: A case series.

Headache
2022

Central Nervous System Involvement of Multiple Myeloma Presenting as Short-lasting Unilateral Neuralgiform Headache with Conjunctival Injection and Tearing: A Case Report.

The Neurohospitalist
2022

CT-Guided Thermocoagulation of the Pterygopalatine Ganglion for Refractory Trigeminal Autonomic Cephalalgia.

Pain and therapy
2022

Effects of acute and preventive therapies for episodic and chronic cluster headache: A scoping review of the literature.

Headache
2022

[Autonomic Disorders in Trigeminal Autonomic Cephalalgias: An Update].

Brain and nerve = Shinkei kenkyu no shinpo
2022

Characteristics of pre-cluster symptoms in cluster headache: A cross-sectional multicentre study.

Cephalalgia : an international journal of headache
2022

Gamma Knife radiosurgery for the treatment of cluster headache: a systematic review.

Neurosurgical review
2021

Cluster headache epidemiology including pediatric onset, sex, and ICHD criteria: Results from the International Cluster Headache Questionnaire.

Headache
2021

They Look but Do Not See-Gaze-Evoked Eyelid Spasm.

Movement disorders clinical practice
2021

A New Treatment Option for Children With Refractory Chronic Paroxysmal Hemicranias: Occipital Nerve Stimulation.

Pediatric neurology
2021

SUNCT/SUNA in Pediatric Age: A Review of Pathophysiology and Therapeutic Options.

Brain sciences
2021

Pain Relief in Short-Lasting Unilateral Neuralgiform Headache with Conjunctival inJection and Tearing Syndrome with Intravenous Ketamine: A Case Report.

Acta neurologica Taiwanica
2021

PER Gene Family Polymorphisms in Relation to Cluster Headache and Circadian Rhythm in Sweden.

Brain sciences
2022

Aura in trigeminal autonomic cephalalgia is probably mediated by comorbid migraine with aura.

Cephalalgia : an international journal of headache
2021

Pediatric-onset trigeminal autonomic cephalalgias: A systematic review and meta-analysis.

Cephalalgia : an international journal of headache
2021

Hemicrania continua in a family: A report of two cases.

Headache
2021

The orexin/hypocretin system in neuropsychiatric disorders: Relation to signs and symptoms.

Handbook of clinical neurology
2021

A brief diagnostic screen for cluster headache: Creation and initial validation of the Erwin Test for Cluster Headache.

Cephalalgia : an international journal of headache
2021

Association of Cannabis Use During Adolescence With Neurodevelopment.

JAMA psychiatry
2021

The sensitivity to change of the cluster headache quality of life scale assessed before and after deep brain stimulation of the ventral tegmental area.

The journal of headache and pain
2021

Occipital Neuralgia and Its Management: An Overview.

Neurology India
2021

SUNCT and SUNA: An Update.

Neurology India
2021

Paroxysmal Hemicrania: An Update.

Neurology India
2021

Cluster Headache: A Review and Update in Treatment.

Current neurology and neuroscience reports
2021

Headache from clinically confirmed hemicrania continua arising from the sternocleidomastoid muscle: a case report.

BMC neurology
2021

Primary headache research output and association with socioeconomic factors in Southeast Asia: a bibliometric analysis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2021

Paroxysmal hemifacial pain: A report of two cases.

Headache
2021

The first-line cluster headache medication verapamil alters the circadian period and elicits sex-specific sleep changes in mice.

Chronobiology international
2021

Trigeminal Autonomic Cephalalgia following Corneal Transplantation: A Case Report and Review of the Literature.

Pain medicine (Malden, Mass.)
2021

A retrospective observation on 105 patients with chronic cluster headache receiving indomethacin.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

Endovascular treatment of trigeminal neuralgia with cranial autonomic symptoms due to a right-sided petrous ridge dAVF.

British journal of neurosurgery
2021

Cluster headache is one of the most intensely painful human conditions: Results from the International Cluster Headache Questionnaire.

Headache
2020

Trigeminal neurovascular contact in SUNCT and SUNA: a cross-sectional magnetic resonance study.

Brain : a journal of neurology
2021

Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives.

Fundamental & clinical pharmacology
2021

Drug profile: galcanezumab for prevention of cluster headache.

Expert review of neurotherapeutics
2020

Hemicrania Continua With Scintillating Scotoma: A Rare Presentation.

Cureus
2021

Clinical characteristics of pre-attack symptoms in cluster headache: A large series of Korean patients.

Cephalalgia : an international journal of headache
2020

Paroxysmal hemicrania masquerading as a stroke in an elderly gentleman: case report.

BMC geriatrics
2021

SUNCT/SUNA in children and adolescents: Application of ICHD-3 criteria and treatment response: Case series of 13 SUNCT/SUNA pediatric cases.

Cephalalgia : an international journal of headache
2021

Refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing responsive to anti-calcitonin gene-related peptide monoclonal antibodies: A case report.

Cephalalgia : an international journal of headache
2020

Machine learning-based automated classification of headache disorders using patient-reported questionnaires.

Scientific reports
2020

Open-Label, Multi-Dose, Pilot Safety Study of Injection of OnabotulinumtoxinA Toward the Otic Ganglion for the Treatment of Intractable Chronic Cluster Headache.

Headache
2020

Cluster headache therapies: pharmacology and mode of action.

Expert review of clinical pharmacology
2020

Prevalence of familial cluster headache: a systematic review and meta-analysis.

The journal of headache and pain
2020

Sensory function in headache: a comparative study among patients with cluster headache, migraine, tension-type headache, and asymptomatic subjects.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2020

Trigeminal Autonomic Cephalalgia Secondary to Spontaneous Trigeminal Hemorrhage.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
2020

Cerebral Sinus Venous Thrombosis Mimicking Probable Paroxysmal Hemicrania: A Case Report.

Headache
2020

SUNCT-Induced Jaw Opening: A Rare Trigeminal Autonomic Phenotype.

Headache
2019

Intractable headache with autonomic features after gamma knife radiosurgery: A case report.

Iranian journal of neurology
2020

Temporal changes of circadian rhythmicity in cluster headache.

Cephalalgia : an international journal of headache
2019

Trigeminal Autonomic Cephalalgias.

Neurologic clinics
2020

Case report: Orbital myositis triggering oxygen-responsive cluster headache.

Cephalalgia : an international journal of headache
2019

Managing cluster headache.

Practical neurology
2019

Do paroxysmal hemicrania and hemicrania continua represent different headaches? A retrospective study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2019

Trigeminal autonomic cephalalgias presenting in a multidisciplinary tertiary orofacial pain clinic.

The journal of headache and pain
2019

[Symptomatic trigeminal autonomic cephalalgia without headache].

Ideggyogyaszati szemle
2019

Ventral tegmental area deep brain stimulation for chronic cluster headache: Effects on cognition, mood, pain report behaviour and quality of life.

Cephalalgia : an international journal of headache
2019

Chronic persistent Horner's syndrome in trigeminal autonomic cephalalgia subtypes and alleviation with treatment: two case reports.

Journal of medical case reports
2019

Field testing the diagnostic criteria of cluster headache in the third edition of the International Classification of Headache Disorders: A cross-sectional multicentre study.

Cephalalgia : an international journal of headache
2019

Trigeminal Autonomic Cephalalgia and Facial Pain: A Review and Case Presentation.

Journal of oral & facial pain and headache
2019

Sphenopalatine Neuralgia: An Independent Neuralgia Entity. Pooled Analysis of a Case Series and Literature Review.

Headache
2019

Effectiveness of Oxygen and Other Acute Treatments for Cluster Headache: Results From the Cluster Headache Questionnaire, an International Survey.

Headache
2018

Sensory function in cluster headache: an observational study comparing the symptomatic and asymptomatic sides.

Neuropsychiatric disease and treatment
2018

Clinical Features of Probable Cluster Headache: A Prospective, Cross-Sectional Multicenter Study.

Frontiers in neurology
2018

Cluster Headache in a 76-year-old Woman with Onset at the Age of 74: Case Report.

Journal of oral & facial pain and headache
2019

Systematic literature review on the delays in the diagnosis and misdiagnosis of cluster headache.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2019

Evaluation of routine magnetic resonance imaging of patients with chronic orofacial pain.

International journal of oral and maxillofacial surgery
2018

Acute Herpes Zoster Infection With Onset of SUNA: A Rare Case and Literature Review.

Headache
2018

SUNCT and SUNA: an Update and Review.

Current pain and headache reports
2018

Hints on Diagnosing and Treating Headache.

Deutsches Arzteblatt international
2018

Greater Occipital Nerve Injection versus Oral Steroids for Short Term Prophylaxis of Cluster Headache: A Retrospective Comparative Study.

Headache
2018

Secondary (Symptomatic) Trigeminal Autonomic Cephalalgia.

Annals of Indian Academy of Neurology
2018

Classification of Trigeminal Autonomic Cephalalgia: What has Changed in International Classification of Headache Disorders-3 Beta?

Annals of Indian Academy of Neurology
2018

Short-Lasting Unilateral Neuralgiform Headache Attacks.

Annals of Indian Academy of Neurology
2018

Hemicrania Continua Associated with Classic Scintillating Scotoma.

Case reports in neurology
2018

Therapeutic Approaches for the Management of Trigeminal Autonomic Cephalalgias.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
2018

Treatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation.

The journal of headache and pain
2017

Short-Lasting Unilateral Neuralgiform Headache Attacks with Conjunctival Injection and Tearing in a Patient with Varicella-Zoster Virus Encephalomyelitis.

Case reports in infectious diseases
2018

Cluster headache and middle meningeal artery dural arteriovenous fistulas: A case report.

Cephalalgia : an international journal of headache
2018

Diagnosis, pathophysiology, and management of cluster headache.

The Lancet. Neurology
2018

Phenotypic and treatment outcome data on SUNCT and SUNA, including a randomised placebo-controlled trial.

Cephalalgia : an international journal of headache
2017

Occipital Nerve Stimulation for Medically Refractory Chronic Paroxysmal Hemicrania.

Headache
2017

A Case of Acoustic Shock with Post-trauma Trigeminal-Autonomic Activation.

Frontiers in neurology
2017

Screening of genetic variants in ADCYAP1R1, MME and 14q21 in a Swedish cluster headache cohort.

The journal of headache and pain
2018

Long-term follow up of intractable chronic short lasting unilateral neuralgiform headache disorders treated with occipital nerve stimulation.

Cephalalgia : an international journal of headache
2017

LASH: A Review of the Current Literature.

Current pain and headache reports
2017

Clinical Characteristics and Treatment Patterns Among Patients Diagnosed With Cluster Headache in U.S. Healthcare Claims Data.

Headache
2018

Natural course of untreated cluster headache: A retrospective cohort study.

Cephalalgia : an international journal of headache
2017

Headache in Neuromyelitis Optica.

Current pain and headache reports
2017

Non-invasive Neuromodulation in Primary Headaches.

Current pain and headache reports
2017

Treatment of intractable hemicrania continua by occipital nerve stimulation.

Journal of neurology, neurosurgery, and psychiatry
2017

Which Matters More? A Retrospective Cohort Study of Headache Characteristics and Diagnosis Type in Soldiers with mTBI/Concussion.

Headache
2017

Cracked tooth syndrome mimicking trigeminal autonomic cephalalgia: A report of four cases.

Quintessence international (Berlin, Germany : 1985)
2017

Clinical Features of Cluster Headache Patients in Korea.

Journal of Korean medical science
2015

O003. Red ear syndrome: a new form of trigeminal autonomic cephalalgia?

The journal of headache and pain
2017

Cluster headache and other TACs: Pathophysiology and neurostimulation options.

Headache
2017

Peripheral Nerve Blocks for the Treatment of Headache in Older Adults: A Retrospective Study.

Headache
2017

Hemicrania Continua: Beneficial Effect of Non-Invasive Vagus Nerve Stimulation in a Patient With a Contraindication for Indomethacin.

Headache
2018

Post herpes zoster SUNCT like syndrome: Insights from two case reports.

Cephalalgia : an international journal of headache
2017

Two Cases of Hemicrania Continua-Trigeminal Neuralgia Syndrome: Expanding the Spectrum of Trigeminal Autonomic Cephalalgia-Tic (TAC-TIC) Syndrome.

Headache
2017

Facial epicrania fugax: A prospective series of eight new cases.

Cephalalgia : an international journal of headache
2016

The development and validation of the Cluster Headache Quality of life scale (CHQ).

The journal of headache and pain
2016

Ventral tegmental area deep brain stimulation in refractory short-lasting unilateral neuralgiform headache attacks.

Brain : a journal of neurology
2016

Treatment of Cluster Headache: The American Headache Society Evidence-Based Guidelines.

Headache
2016

[Botulinum toxin type A in headache treatment : Established and experimental indications].

Der Nervenarzt
2016

A Cross-Sectional Clinic-Based Study in Patients With Side-Locked Unilateral Headache and Facial Pain.

Headache
2016

Trigeminal autonomic cephalalgia as a presenting feature of Neuromyelitis Optica: "A rare combination of two uncommon disorders".

Multiple sclerosis and related disorders
2017

Migraine-tic syndrome: Two further case reports.

Cephalalgia : an international journal of headache
2016

A Practical Approach to Autonomic Dysfunction in Patients with Headache.

Current neurology and neuroscience reports
2016

Prevalence and Features of a Probable Diagnosis in First-Visit Headache Patients Based on the Criteria of the Third Beta Edition of the International Classification of Headache Disorders: A Prospective, Cross-Sectional Multicenter Study.

Headache
2016

SUNCT syndrome: A cohort of 15 Portuguese patients.

Cephalalgia : an international journal of headache
2016

Familial SUNCT in mother and son.

Cephalalgia : an international journal of headache
2016

Trigeminal neuralgia (part I): Revisiting the clinical phenotype.

Cephalalgia : an international journal of headache
2016

Trigeminal neuralgia (part II): Factors affecting early pharmacotherapeutic outcome.

Cephalalgia : an international journal of headache
2015

Repetitive Transcranial Magnetic Stimulation (rTMS)-Induced Trigeminal Autonomic Cephalalgia.

Noro psikiyatri arsivi
2015

Pharmacotherapy options for cluster headache.

Expert opinion on pharmacotherapy
2015

How effective is melatonin as a preventive treatment for hemicrania continua? A clinic-based study.

Headache

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

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Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

Ainda não existe comunidade no Raras para Cefalalgia autonômica do trigêmeo

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Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Secondary trigeminal autonomic cephalgia with cavernous sinus involvement: a diagnostic challenge.
    BMJ case reports· 2025· PMID 41022411mais citado
  2. Onset of secondary SUNCT syndrome with concomitant occipital neuralgia after dorsal medullary infarction.
    BMJ case reports· 2025· PMID 40154552mais citado
  3. Risk of Attempted and Completed Suicide in Persons Diagnosed With Headache.
    JAMA neurology· 2025· PMID 39899309mais citado
  4. Understanding the Diagnosis of Primary Headaches in Outpatients Referred to Japanese Headache Specialists.
    Cureus· 2025· PMID 41589140mais citado
  5. A case report: Infrazygomatic approach neurocryoablation of the sphenopalatine ganglion under cone beam computer tomography guidance in treating refractory headaches.
    Interventional pain medicine· 2025· PMID 41378123mais citado
  6. [Recent Advances in Trigeminal Nerve Understanding: Anatomy, Pathophysiology, and Emerging Therapeutic Targets].
    Brain Nerve· 2026· PMID 41974435recente
  7. A Comprehensive Review of Trigeminal Autonomic Cephalalgias.
    Phys Med Rehabil Clin N Am· 2025· PMID 41167853recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:157843(Orphanet)
  2. MONDO:0015530(MONDO)
  3. GARD:20017(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q2453193(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Cefalalgia autonômica do trigêmeo
Compêndio · Raras BR

Cefalalgia autonômica do trigêmeo

ORPHA:157843 · MONDO:0015530
CID-11
Ensaios
7 ativos
MedGen
UMLS
C1565172
EuropePMC
Wikidata
Papers 10a
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