A neuralgia do trigêmeo é um distúrbio nervoso que causa dor tipo facada ou choque elétrico em partes do rosto. A dor dura de alguns segundos a alguns minutos e geralmente ocorre em apenas um lado do rosto. Também pode causar espasmos musculares no rosto ao mesmo tempo que a dor. A dor pode resultar da pressão de um vaso sanguíneo contra o nervo trigêmeo (o nervo que transporta a dor, a sensação e outras sensações do cérebro para a pele do rosto), como uma complicação da esclerose múltipla ou devido à compressão do nervo por um tumor ou cisto. Em alguns casos, a causa é desconhecida. As opções de tratamento incluem medicamentos, cirurgia e abordagens complementares.
Introdução
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A neuralgia do trigêmeo é um distúrbio nervoso que causa dor tipo facada ou choque elétrico em partes do rosto. A dor dura de alguns segundos a alguns minutos e geralmente ocorre em apenas um lado do rosto. Também pode causar espasmos musculares no rosto ao mesmo tempo que a dor. A dor pode resultar da pressão de um vaso sanguíneo contra o nervo trigêmeo (o nervo que transporta a dor, a sensação e outras sensações do cérebro para a pele do rosto), como uma complicação da esclerose múltipla ou devido à compressão do nervo por um tumor ou cisto. Em alguns casos, a causa é desconhecida. As opções de tratamento incluem medicamentos, cirurgia e abordagens complementares.
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 12 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 18 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
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Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
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Publicações mais relevantes
Mostrando amostra de 200 publicações de um total de 3.868
A Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.
Este estudo inovador desvenda a patogénese da neuralgia trigeminal (NT), uma dor severa e pouco compreendida, ao identificar uma via neural específica no cérebro (TG-Sp5CTac1-PBNTac1) que impulsiona o seu desenvolvimento. A inibição de neurónios específicos nesta via ou a redução do gene Tachykinin 1 (Tac1) demonstrou prevenir ou atenuar significativamente a dor, oferecendo novos e promissores alvos para o desenvolvimento de tratamentos mais eficazes para pacientes e médicos.
🇧🇷 traduzidoRetrospective evaluation of treatment outcomes of Gasserian ganglion radiofrequency thermocoagulation in trigeminal neuralgia patients with multiple sclerosis.
Este estudo retrospectivo avaliou a eficácia e segurança da termocoagulação e radiofrequência pulsada do gânglio de Gasser em 12 pacientes com neuralgia do trigêmeo (NT) secundária à esclerose múltipla (EM), uma condição rara e debilitante. Os resultados foram promissores: todos os pacientes relataram mais de 50% de alívio da dor em seis meses, com 75% mantendo o benefício em 12 meses, e o tratamento foi bem tolerado, sem complicações significativas. Embora represente uma das maiores séries de casos sobre esta técnica em pacientes com EM, os autores ressaltam a necessidade de estudos futuros com amostras maiores para validar plenamente essas descobertas encorajadoras para pacientes e médicos.
🇧🇷 traduzidoInternal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system.
Este estudo avaliou a neurólise interna (IN) como um tratamento eficaz e seguro para a dor facial atípica (DFA), uma condição que difere da neuralgia do trigêmeo típica. A pesquisa demonstrou que 75% dos pacientes com DFA obtiveram alívio significativo da dor com a IN, sem complicações maiores. Para médicos, o estudo ressalta que, ao contrário da neuralgia típica que muitas vezes se resolve com descompressão vascular, a DFA frequentemente requer dissecção e neurólise interna, especialmente em pacientes com esclerose do nervo trigêmeo, destacando estratégias de tratamento distintas.
🇧🇷 traduzidoNeuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis.
Uma análise genética recente, utilizando randomização mendeliana, revelou que ansiedade e depressão podem aumentar o risco de constipação. Inversamente, a constipação eleva o risco de ansiedade, depressão e, de forma significativa, **quase dobra o risco de desenvolver neuralgia do trigêmeo** (OR = 1.897). Para pacientes e médicos, este achado enfatiza a importância de identificar e gerenciar proativamente os sintomas de constipação em indivíduos com condições neuropsiquiátricas, incluindo a neuralgia do trigêmeo, visando melhorar sua saúde e qualidade de vida.
🇧🇷 traduzidoA case of myelin oligodendrocyte glycoprotein antibody-associated disease presenting with radiculopathies.
Este artigo é relevante para pacientes e médicos porque destaca que a neuralgia do trigêmeo pode ser uma manifestação da doença MOGAD, uma condição desmielinizante que afeta não só o sistema nervoso central, mas também o periférico. Para um diagnóstico preciso, é crucial considerar a pesquisa de anticorpos MOG no líquor (CSF) em casos de forte suspeita clínica ou envolvimento misto (central e periférico), mesmo que os testes sanguíneos (soro) sejam negativos.
🇧🇷 traduzidoPublicações recentes
Monitoring Nitric Oxide in Trigeminal Neuralgia Rats with a Cerium Single-Atom Nanozyme Electrochemical Biosensor.
Chrono-anatomical precision in salvage therapy for recurrent trigeminal neuralgia: mechanistic insights and cost-utility analysis of percutaneous balloon compression.
Demonstrating Petrous Dural Incision Technique for Vascular Releasing and Transposition of Dura-Embedded Subarcuate Loop of Anterior Inferior Cerebellar Artery During Retrosigmoid Approach.
📚 EuropePMC5.898 artigos no totalmostrando 194
Early glucocorticoid therapy for brainstem edema associated with acute inflammatory Teflon granuloma after microvascular decompression for trigeminal neuralgia: illustrative case.
Journal of neurosurgery. Case lessonsInfluence of Neurovascular Conflict on the Outcome of Primary Gamma Knife Radiosurgery for Trigeminal Neuralgia: A Single-Center Retrospective Study.
Stereotactic and functional neurosurgeryA Novel Mobile C-Arm Fluoroscopic Imaging of the Foramen Ovale and Its Anatomical Principles.
Journal of pain researchSuccessful treatment of neuropathic symptoms in acute trigeminal herpes zoster with high-dose intravenous ascorbic acid: A two-case report.
Explore (New York, N.Y.)How I do it: identification and preservation of trigeminocerebellar artery from superior petrosal vein during endoscopic microvascular decompression for trigeminal neuralgia.
Acta neurochirurgicaEvaluation of trigeminal nerve microvascular decompression with sensory root neurolysis.
Pain managementDevelopment of an Expert Consensus on Electroacupuncture for Trigeminal Neuralgia Using the Delphi Method: A Study Protocol.
Journal of pain researchEvaluation of Watson constraints in Gamma Knife stereotactic radiosurgery for medically intractable trigeminal neuralgia in the era of preplanning MRI with frame-based cone beam CT treatment.
Clinical neurology and neurosurgeryPhosphoproteomics uncovers a neuroimmune perspective on trigeminal neuralgia: sexually dimorphic regulatory networks linking calcium channels to the complement cascade.
Frontiers in immunologyA comprehensive evaluation of non-vascular prepontine cistern anatomy influencing trigeminal nerve vulnerability using machine learning-based morphometric analysis.
Frontiers in medicineThe Mind Locker Method: A Lived-Experience Model of Chronic Pain Self-Regulation and Resilience.
Qualitative health researchHistorical evolution of microvascular decompression after Jannetta's establishment: Anatomical maps and physiological compasses-a narrative review.
Acta neurochirurgicaTemporalis Muscle-Originated Supraorbital Neuralgia Misdiagnosed as Trigeminal Neuralgia.
The Journal of craniofacial surgeryMachine learning-based quantification of neurovascular compression for correlation with trigeminal neuralgia pain outcomes.
PainDexmedetomidine Use and Intraoperative Bradycardia During Radiofrequency Rhizotomy for Trigeminal Neuralgia: A Retrospective Observational Study.
Drug design, development and therapyHemodynamic parameters as biomarkers for predicting microvascular decompression efficacy in classic trigeminal neuralgia.
Journal of neurosurgeryA Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)Vertically Crowded Small Posterior Fossa Is a Possible Cause of Trigeminal Neuralgia in Young Adults: Operative Nuances of Microvascular Decompression Based on Associated Morphological Features.
Operative neurosurgery (Hagerstown, Md.)Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients.
Pain practice : the official journal of World Institute of PainA Diagnostic Pitfall: Carbamazepine-Induced Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Syndrome Masquerading As Angiotensin-Converting Enzyme Inhibitor Angioedema.
CureusRetrospective evaluation of treatment outcomes of Gasserian ganglion radiofrequency thermocoagulation in trigeminal neuralgia patients with multiple sclerosis.
Turkish journal of medical sciencesA case of trigeminal nerve neurosarcoidosis initially presenting with isolated neurological findings mimicking trigeminal schwannoma: a case report and review of the literature.
Journal of medical case reportsPitfalls in Trigeminal Nerve Mapping in Neurosurgery: The Mystery of the Unexpected Motor Responses.
Journal of neurological surgery. Part B, Skull baseMini-invasive Anterior Petrosal Intertentorial Approach for Trigeminal Neuralgia: Rationale and Limits of the Technique.
Journal of neurological surgery. Part B, Skull baseIndividualized rs-fMRI reveals brain-circuit heterogeneity and predicts early recurrence in trigeminal neuralgia.
Frontiers in psychiatryExploring the Molecular Mechanism of Shaoyao Gancao Decoction for Trigeminal Neuralgia Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation.
ACS omegaFrom microvascular decompression to radiosurgery: a network meta-analysis of interventions for medication-refractory trigeminal neuralgia.
Neurosurgical reviewPredictive value of preoperative white and gray matter microstructural alterations for microvascular decompression outcome in classical trigeminal neuralgia.
Cephalalgia : an international journal of headacheInternal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system.
Surgical neurology internationalNeuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis.
Brain and behaviorTrigeminal nerve transposition by sling-pulling technique in combination with macrovascular transposition for giant basilar artery-induced trigeminal neuralgia via a combined transpetrosal approach.
Acta neurochirurgicaThe ethyl acetate extract of Schefflera kwangsiensis ameliorates oxaliplatin-induced peripheral neuropathic pain via SERCA2b.
Chinese journal of natural medicinesComputed Tomography-Guided Short-Term Gasserian Ganglion Stimulation for the Treatment of Idiopathic Trigeminal Neuralgia: A Two-Case Report.
Pain medicine case reportsMuscle Versus Teflon as Interposition Grafts in Microvascular Decompression for Primary Trigeminal Neuralgia: Institutional Series, Systematic Review, and Meta-Analysis.
Operative neurosurgery (Hagerstown, Md.)Investigation of miRNAs affecting schwann cells in patients with trigeminal neuralgia.
Molecular biology reportsAdvanced, pharmacological and complementary interventions for chronic or recurrent orofacial pain conditions: a systematic evidence map with selective meta-analyses.
The journal of headache and painOutcomes of microvascular decompression for trigeminal neuralgia: a retrospective analysis from a Mexican high-specialty center.
Arquivos de neuro-psiquiatriaA Comprehensive Mendelian Randomization Study of Bidirectional Causal Relationships Between Pain and Mental Disorders.
Journal of pain researchClassification of solitary pontine lesion-related trigeminal neuralgia.
Cephalalgia : an international journal of headacheRecognizing solitary pontine lesion-related trigeminal neuralgia as a distinct entity: The need for an updated ICHD classification.
Cephalalgia : an international journal of headacheOn the topical issue of assisted dying: the insurmountable challenges of human existence, and the right to exit.
Frontiers in public healthFixel‑based analysis reveals distributed white matter alterations associated with pain severity in trigeminal neuralgia.
The journal of headache and painEarly Postoperative Hypesthesia after Microvascular Decompression for Trigeminal Neuralgia is a Predictor of Long-Term Pain Relief: A Long-Term Cohort Study.
World neurosurgeryTrigeminal neuralgia: why beautiful images don't always make the diagnosis.
European radiologyAnticonvulsant Therapy in Trigeminal Neuralgia: A Class-Oriented Systematic Review.
Medicines (Basel, Switzerland)Pain in multiple sclerosis: clinical phenotypes and therapeutic strategies - a narrative review.
Pain reportsNr4a1 regulates microglia overactivation-mediated neuroinflammation to ameliorate cognitive impairment in trigeminal neuralgia rats.
The journal of headache and painLinear Accelerator Mask-Based Radiosurgery for Trigeminal Neuralgia: Prospective Evaluation of 50 Patients.
World neurosurgeryPartial sensory rhizotomy in therapy-refractory and recurrent trigeminal neuralgia - a single center experience.
Acta neurochirurgicaKeyhole retrosigmoid approach for microvascular decompression surgery: systematic review and single-arm meta-analysis.
Neurosurgical reviewExperience and Efficacy Evaluation of Microvascular Decompression and Selective Nerve Root Dissection in the Treatment of Trigeminal Neuralgia Combined With Glossopharyngeal Neuralgia.
The Journal of craniofacial surgeryTrigeminal somatosensory evoked potentials for intraoperative monitoring and prognostic prediction in microvascular decompression for trigeminal neuralgia: a prospective cohort study.
Frontiers in neurologyA case of myelin oligodendrocyte glycoprotein antibody-associated disease presenting with radiculopathies.
Rinsho shinkeigaku = Clinical neurologyEfficacy and safety of percutaneous balloon compression for trigeminal neuralgia associated with multiple sclerosis: A systematic review and meta-analysis.
Multiple sclerosis and related disordersThe utility of partial sensory rhizotomy and adjunct procedures in the surgical management of trigeminal neuralgia secondary to multiple sclerosis.
Journal of neurosurgeryPhotobiomodulation Therapy in the Management of Orofacial Neuropathic Pain-WALT Position Paper 2026.
Journal of clinical medicinePreneurosurgical Care for Patients With Trigeminal Neuralgia.
JAMA network openHydrocephalus-associated trigeminal neuralgia.
Frontiers in neurology[Posterior petrous meningiomas: clinical manifestations, anatomical relationships and postoperative outcomes].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoGlymphatic dysfunction in trigeminal neuralgia: A multimodal MRI study.
Neurobiology of diseaseDiagnostic challenges of trigeminal neuralgia in dental settings: a retrospective study.
BMC neurologyRadiofrequency Versus Percutaneous Balloon Compression for Trigeminal Neuralgia: A Systematic Review and Meta-Analysis.
World neurosurgeryDouble-faced microprobe for vessel transposition in microvascular decompression: technical note.
Acta neurochirurgicaPivotal Factors for Minimizing the Risks of Therapeutic Failure in Trigeminal Neuralgia and Hemifacial Spasm.
Current pain and headache reportsLateral Orbitotomy for Trigeminal Schwannomas: Surgical Technique, Outcomes, and Limitations.
Operative neurosurgery (Hagerstown, Md.)CyberKnife Stereotactic Radiosurgery for Vestibular Schwannomas: Systematic Review and Meta-Analysis of Long-Term Tumor Control and Hearing Preservation Outcomes.
Neurosurgery practiceShort-term infraorbital nerve electrical stimulation for herpes zoster herpetic trigeminal maxillary division neuralgia: A case report.
MedicinePosterior circulation hypoperfusion plays an important role in refractory otalgia: case report.
BMC surgeryEffectiveness of laser photobiomodulation in the management of trigeminal neuralgia: a systematic review and meta-analysis.
Lasers in medical scienceTrends, Insights, and Challenges in the Treatment of Trigeminal Neuralgia: A Bibliometric Analysis of The Top 200 Most Influential Articles.
Journal of neurological surgery. Part A, Central European neurosurgeryVentral Compression of the Trigeminal Nerve by the Superior Cerebellar Artery: A Novel Intraoperative Classification and Clinical Significance.
The Journal of craniofacial surgeryMicrovascular decompression of aberrantly looped anterior inferior cerebellar artery: illustrative case.
Journal of neurosurgery. Case lessonsSelecting Neuromodulation Devices For Chronic Pain Conditions: A Narrative Review.
Pain physicianSafety and Efficacy of Microvascular Decompression for Trigeminal Neuralgia in the Octogenarian Population: Insights From a Propensity Score-Adjusted and Matched Analysis.
NeurosurgeryShredded vs. pledget teflon in microvascular decompression for trigeminal neuralgia: a retrospective comparative study.
British journal of neurosurgeryClinical Characteristics and Treatment Resistance of Trigeminal Neuralgia in Multiple Sclerosis Patients: A Retrospective Observational Study.
Noro psikiyatri arsiviComparison of Gasserian ganglion conventional radiofrequency ablation and peripheral nerve pulsed radiofrequency in trigeminal neuralgia: a retrospective cohort study.
Journal of oral & facial pain and headacheCausal association between multiple sclerosis and trigeminal neuralgia: A Mendelian randomization study with meta-analysis.
Cranio : the journal of craniomandibular practicePredictors of Postoperative Complications After Microvascular Decompression for Trigeminal Neuralgia and Hemifacial Spasm: A Retrospective Cohort Study.
The Journal of craniofacial surgeryRepeat posterior fossa exploration and external neurolysis for recurrent trigeminal neuralgia following microvascular decompression.
Frontiers in surgeryNo Glymphatic Dysfunction in Trigeminal Neuralgia: A Preliminary Study.
Brain and behaviorRisk Factors Associated with Dentofacial Anomalies [Including Malocclusion] in Adults.
Bioengineering (Basel, Switzerland)Ultrasound- and CT-Guided Medial-to-Lateral Radiofrequency Ablation of the Infraorbital Nerve for Persistent Idiopathic Dentoalveolar Pain: A Trajectory-Based Approach.
Diagnostics (Basel, Switzerland)When Cancer Mimics Pain: Maxillary Primary Intraosseous Carcinoma Misdiagnosed as Trigeminal Neuralgia.
Dentistry journalCurrent Practice Patterns in Microvascular Decompression for Trigeminal Neuralgia: Results From an International Survey in Central Europe.
CureusCalretinin Contributes to Trigeminal Neuropathic Pain Downstream of Cavα2δ1.
ACS chemical neuroscienceRabies Virus Glycoprotein-Decorated Liposomes in Thermosensitive Nasal Spray Gels: Facilitating Retrograde Neural Transport for Targeted Trigeminal Neuralgia Therapy.
ACS nanoCausal interplay between trigeminal neuralgia and systemic inflammatory markers: A bidirectional Mendelian randomization study.
MedicineThe use of cellular therapies for trigeminal neuralgia: a systematic review of behavioral and molecular outcomes.
Neurosurgical reviewComparative efficacy of microvascular decompression and radiofrequency rhizotomy in idiopathic trigeminal neuralgia with a neurovascular contact without root distortion.
British journal of neurosurgeryEpidemiological and demographic patterns of pediatric trigeminal neuralgia: nationwide trends in diagnosis and treatment over a decade.
Journal of neurosurgery. PediatricsTrigeminal neuralgia caused by a transfixed arterial loop: illustrative case.
Journal of neurosurgery. Case lessonsBeyond the physical dose: implications of biologically effective dose variations in the stereotactic radiosurgical treatment of trigeminal neuralgia.
Journal of neurosurgeryLow-intensity pulsed ultrasound ameliorates partial infraorbital nerve ligation-induced trigeminal neuropathic pain through inhibiting Schwann cell Pannexin 1 channel.
Frontiers in immunologyTrigeminal neuralgia-like pain in a vagus nerve stimulation super-responder with drug-resistant idiopathic generalized epilepsy: A case report.
Epilepsy & behavior reportsBovine pericardial patch in an eggroll fashion and teflon felt microvascular decompression for trigeminal neuralgia and hemifacial spasm: A retrospective study.
MedicineThe Use of Botulinum Toxin Injections in Peripheral Neuropathic Pain: A Systematic Review of Efficacy and Safety Outcomes.
Pain research & managementMicrovascular decompression for vertebrobasilar dolichoectasia-related primary trigeminal neuralgia: surgical approaches, technical considerations, and clinical outcomes.
Neurosurgical reviewHippocampal myelin damage contributes to cognitive impairment in a rat model of trigeminal neuropathic pain: Neuroprotective and anti-inflammatory effects of atorvastatin.
Neuroscience researchPredictive Model Development for Postoperative Complications in Trigeminal Neuralgia Patients Undergoing Percutaneous Balloon Compression.
World neurosurgeryGamma Knife-Mimicking Radiosurgery With Cyberknife: A Comparison of Dose Prescription Methodologies for the Treatment of Trigeminal Neuralgia.
CureusBMP7 alleviates trigeminal neuralgia by suppressing oxidative stress and activation of satellite glial cells via the NRF2/HO-1 pathway.
Brain, behavior, and immunityPeripheral Nerve Stimulation Is Effective in the Management of Trigeminal Pain: A Systematic Review and meta-analysis.
Current pain and headache reportsElectrophysiological monitoring of trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia.
Acta neurochirurgicaSubcortical neuroimaging signature of painful disorders of the trigeminal nerve: a UK Biobank study.
The journal of headache and painExperimental Study of a Newly Developed Prosthesis and Its Initial Clinical Use in Microvascular Decompression Surgery.
Neurologia medico-chirurgicaSevere Symptomatic Bradycardia Following First-Dose Oxcarbazepine in a Very Elderly Patient on Long-Term Carbamazepine: A Case Report.
CureusAnalysis of Risk Prediction Model for Recurrence of Trigeminal Neuralgia After Percutaneous Balloon Compression.
Pain research & managementSphenopalatine ganglion block in orofacial pain and headache disorders: A review of case reports.
Cranio : the journal of craniomandibular practiceGlobal Incidence and Prevalence of Trigeminal Neuralgia, 1945-2024: A Systematic Review and Meta-Regression Analysis.
Journal of clinical neurology (Seoul, Korea)Eight Decades of Data Reveal a Far Greater Global Burden of Trigeminal Neuralgia.
Journal of clinical neurology (Seoul, Korea)Lymphoma in Meckel cave mimicking trigeminal schwannoma - analysis of misdiagnosis causes and insights into imaging: Case report.
MedicineThe Role of Biological Effective Dose in Gamma Knife Radiosurgery: A Systematic Review Across Multiple Indications.
Journal of clinical medicineDebunking myths in facial pain diagnosis for the pain practitioner.
Regional anesthesia and pain medicineSuccessful Radiosurgical Treatment of Trigeminal Neuralgia and Related Facial Pain Syndromes: The Australian Gamma Knife Experience.
Journal of medical imaging and radiation oncologyResearch Progress on Radiofrequency Treatment of Primary Trigeminal Neuralgia in the V2 Maxillary Nerve.
Pain and therapyMagnetic resonance imaging-based classification of trigeminal nerve-superior cerebellar artery relationships.
World journal of radiologyTRPC6 mediates neuronal hyperexcitability in the lateral habenula to drive trigeminal neuralgia-associated anxiety.
NeuropharmacologyUltrasound-Identified Trigger-Point and Ultrasound-Guided IncobotulinumtoxinA (Xeomin®) Injection for Refractory V2-V3 Trigeminal Neuralgia: A Case Report.
CureusNavigating Neurological Complications in Aesthetic Dermatology: Onset of Trigeminal Neuralgia Following Laser Hair Reduction.
CureusAnaesthesia dolorosa after gamma knife radiosurgery: a cautionary insight into long-term complications.
BMJ case reports[Clinical study on improving the curative effect of acupuncture on primary trigeminal neuralgia by syndrome differentiation and treatment].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatologySpigelia Anthelmia for Uterine Fibroid: Case Report of a Homeopathic Cure Guided by a Urinary Modality.
Homeopathy : the journal of the Faculty of HomeopathyEffects of risk factor-based targeted nursing intervention on psychological status, sleep quality, and pain in patients with trigeminal neuralgia.
Frontiers in neurologyTreatment strategy in stereotactic radiosurgery for trigeminal neuralgia, essential tremor, and coexisting intracranial tumors: The impact of biologically effective dose on clinical outcome.
Journal of applied clinical medical physicsKeeping It Simple: A Case Report on Atomized Intranasal 1% Lidocaine as an Effective Treatment for Pain Crisis Due to Trigeminal Neuralgia.
CureusCerebellar neurocan gene expression is a common pathogenic factor of trigeminal neuralgia and depression.
The journal of headache and painAnatomical Variations of the Foramen Ovale and Trigeminal Neuralgia.
CureusTreatment-Induced Diabetic Neuropathy: A Case Report on Multimodal Pain Management in a Young Patient With Type I Diabetes.
CureusUpdates on the Proposed Botulinum Toxin A Mechanisms of Action in Orofacial Pain: A Review of Animal Studies.
ToxinsHistory and Development of Clinical Use of Functional Stereotaxy for Radiation Oncologists: From Its Origins to Its Current State.
Current oncology (Toronto, Ont.)Absence of Meckel's cave causing trigeminal neuralgia.
Acta neurologica BelgicaStaged posterior fossa decompression and microvascular decompression for trigeminal neuralgia in autosomal dominant osteopetrosis type I: A case report.
MedicineA mouse model of classical trigeminal neuralgia via intradural compression of the trigeminal nerve.
The journal of headache and painAntinociceptive role of IL-10/STAT3 signaling in trigeminal neuropathic pain male rat model through Pomc and β-endorphin.
Neuroscience lettersCalcitonin gene-related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal-mediated headshaking.
Equine veterinary journalUSP19 restores mitochondrial function in neurons by deubiquitinating FUS to alleviate trigeminal neuralgia.
Experimental brain research[LIU Xing's experience in treatment of primary trigeminal neuralgia by the integration of acupuncture and medication].
Zhongguo zhen jiu = Chinese acupuncture & moxibustionRadiation Therapy for Non-Malignant Central Nervous System Tumors, Disorders, and Illnesses - Current Applications and Future Directions.
Seminars in radiation oncologyAneurysm clip suspension-assisted microvascular decompression for trigeminal neuralgia: a case report and literature review.
BMC surgeryA large-scale dataset of pre- and postsurgical MRI data from patients with chronic trigeminal neuralgia.
Scientific dataNursing of Computed Tomography-Guided Percutaneous Balloon Compression for Primary Trigeminal Neuralgia under Local Anesthesia and Intravenous Analgesia.
Pain management nursing : official journal of the American Society of Pain Management NursesMicrovascular decompression versus percutaneous balloon compression for trigeminal neuralgia: a systematic review and meta-analysis of double-arm studies.
Neurological researchFacial Pain Mimicking Trigeminal Neuralgia Secondary to Low-Cervical Spondylosis: A Case Report and Comprehensive Literature Review.
CureusGenetically predicted the causal relationship between gut-brain axis and chronic pain: a Mendelian randomization study.
Human genomicsL3MBTL2 as a novel therapeutic target for trigeminal neuralgia: evidence from integrated TWAS, multi-tissue MR, and experimental validation.
The journal of headache and painA case report: Infrazygomatic approach neurocryoablation of the sphenopalatine ganglion under cone beam computer tomography guidance in treating refractory headaches.
Interventional pain medicineA novel scoring system as a predictor for delayed pain disappearance after percutaneous balloon compression for trigeminal neuralgia.
European journal of medical researchBiologically Effective Dose and Dose Rate in Gamma Knife Radiosurgery for Trigeminal Neuralgia: A Systematic Review and Meta-Analysis.
Advances in radiation oncologyThe Neural Mechanisms of rTMS and Placebo Effects in Trigeminal Neuralgia: Evidence From fMRI Network Dynamics.
Journal of pain researchEfficacy analysis of percutaneous balloon compression therapy for trigeminal neuralgia guided by three-dimensional digital subtraction angiography navigation.
Frontiers in neurologyLong-term outcomes of microvascular decompression for trigeminal neuralgia in multiple sclerosis: a systematic review and meta-analysis.
Journal of neurosurgeryUltra-early Gamma Knife stereotactic radiosurgery for trigeminal neuralgia (URGEnt-TN): study protocol for a single-center, two-arm, parallel group design, pragmatic, noninferiority, phase II, randomized controlled trial with intention-to-treat analysis for pre-refractory GK-SRS in classical or idiopathic TN.
TrialsGiant trigeminal schwannoma with cavernous sinus and brainstem involvement: Multimodal imaging and multidisciplinary surgical management.
Radiology case reportsMicrovascular Decompression for Trigeminal Neuralgia Secondary to Vertebrobasilar Dolichoectasia: A Case Report and Review of the Literature.
Asian journal of neurosurgeryTrigeminal nerve root compression induced neuroinflammatory response promotes mechanical allodynia through the CGRP/SP-Piezo2 axis via Ca2+ signaling.
Cellular & molecular biology lettersPercutaneous Balloon Compression Exerts Multidimensional Efficacy in Trigeminal Neuralgia via Neuroinflammation and Neurotransmitter Regulation.
World neurosurgeryStereotactic radiosurgery for trigeminal neuralgia secondary to Multiple Sclerosis: A systematic review and Meta-Analysis.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaIn Response to Comment on"The Efficacy and Safety of Applying the Combination of Pulsed Radiofrequency and Platelet-Rich Plasma to the Gasserian Ganglion for the Treatment of Idiopathic Trigeminal Neuralgia: A Protocol for A Multi-Center, Prospective, Open-Label, Propensity Score Match Cohort Study".
Pain physicianPulsed Radiofrequency Treatment: Evidence for and Applications in Chronic Pain.
Pain physicianIndeterminate dental pain: clinical characteristics and neurovascular compression; a retrospective case comparative study.
Frontiers in pain research (Lausanne, Switzerland)Anatomical variability of the lateral pterygoid plate and its influence on the dimensions of infratemporal fossa in human skulls.
Scientific reportsVenous sinus stenting for cerebral venous congestion-induced trigeminal neuralgia: A case report.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences[Radiosurgery for neurosurgical diseases (by the 20th anniversary of neuroradiosurgery in Russia)].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoMagnetic resonance imaging in the diagnosis of trigeminal neuralgia: a systematic review of the imaging protocol and diagnostic accuracy.
European radiologyReducing complications using minimally invasive retrosigmoid approach for microvascular decompression in patients with trigeminal neuralgia.
Neurosurgical reviewUse of Cannabidiol and Cannabigerol in the Treatment of Trigeminal Neuralgia and Postherpetic Pain.
Contemporary clinical dentistryAggressive Disease and Poor Clinical Outcome in CEBPα-Mutated Acute Myeloid Leukemia Patient.
Clinical case reportsShort- and Long-Term Pain Relief With Radiofrequency Rhizotomy in Multiple Sclerosis Patients With Trigeminal Neuralgia: A Systematic Review.
CureusAdvantages of trigeminal nucleotractotomy to treat cancer facial pain: a systematic review.
Pain managementPercutaneous glycerol rhizotomies are effective in achieving immediate but not long-term pain reduction in patients with trigeminal neuralgia: A contemporary cohort analysis.
Clinical neurology and neurosurgeryPredictors of Pain Relief after Index Gamma Knife Radiosurgery for Trigeminal Neuralgia: Retrospective Analysis of a 25-Year Series.
Stereotactic and functional neurosurgeryImpact of Ultrasound-guided Superficial Cervical Plexus Block on Early Postoperative Recovery in Patients Undergoing Microvascular Decompression: A Randomized Controlled Trial.
Journal of neurosurgical anesthesiologyReduced volume in the amygdala of trigeminal neuralgia patients: a neuroimaging study with clinical correlates.
Experimental brain researchInternal Neurolysis for Glossopharyngeal Neuralgia without Vascular Compression: Report of 2 Cases.
NMC case report journalTrigeminal root demyelination is sufficient to induce trigeminal neuralgia-like facial pain in adult rodents.
The journal of headache and painAn exploratory study of urinary proteome in trigeminal neuralgia.
Frontiers in molecular biosciencesToothaches of Non-odontogenic Origin.
Dental clinics of North AmericaSurgical Concept and Long-Term Outcomes of Various Case-by-Case Decompressive Techniques for Trigeminal Neuralgia Caused by the Trigeminocerebellar Artery.
Operative neurosurgery (Hagerstown, Md.)Homogeneous groups are required to assess the effect of unilateral thalamotomy by Gamma Knife radiosurgery on refractory trigeminal neuralgia.
Surgical neurology internationalPosterior reversible encephalopathy syndrome after trigeminal microvascular decompression: A case report.
Surgical neurology internationalJujuboside A Alleviates Facial Allodynia of CCI-ION Rats by Inhibiting the Expression of P2X7 Receptor in the Spinal Trigeminal Subnucleus Caudalis.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyBrain aging among individuals with trigeminal neuralgia.
Neurobiology of pain (Cambridge, Mass.)Cranial Neurolymphomatosis Presenting With Trigeminal Neuralgia and Facial and Vagus Nerve Palsies Visualized on Fluorodeoxyglucose Positron-Emission Tomography (FDG PET).
CureusAcute brain swelling due to intraoperative supratentorial subdural hematoma during microvascular decompression: a case report.
Frontiers in surgeryFacial onset sensory and motor neuronopathy: a diagnostic challenge.
Acta neurologica BelgicaRefractory Trigeminal Neuralgia: The Role of MRI in Diagnosing Neurovascular Compression.
Revista de neurologiaIntravenous magnesium and methocarbamol for acute pain crises in refractory trigeminal neuralgia: A retrospective analysis.
HeadacheSomatotopic sensory trigeminal rootlets identification via unmasked trigemino-facial reflexes. Insights from trigeminal nerve surgery.
Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologyEffectiveness of Electroacupuncture Combined with Pregabalin in the Treatment of Trigeminal Herpetic Neuralgia: A Multicenter Randomized Controlled Trial Study Protocol.
Complementary medicine researchA prospective real-world analysis of intravenous eptinezumab in migraine management: the first UK experience.
The journal of headache and painMicrovascular decompression for neurovascular compression syndromes secondary to vertebrobasilar dolichoectasia: a single-center retrospective analysis.
Frontiers in surgeryComparing large language models and human doctors in symptom-driven online medical consultations: A case study on trigeminal neuralgia.
Digital healthAcute intracranial EBV and CMV infections after chemoimmunotherapy for EBV-associated nasopharyngeal carcinoma: a case report and literature review.
Frontiers in oncologyAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- A Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.
- Retrospective evaluation of treatment outcomes of Gasserian ganglion radiofrequency thermocoagulation in trigeminal neuralgia patients with multiple sclerosis.
- Internal neurolysis for atypical facial pain: Clinical outcomes and validation of an intraoperative trigeminal pathology scoring system.
- Neuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis.
- A case of myelin oligodendrocyte glycoprotein antibody-associated disease presenting with radiculopathies.
- Monitoring Nitric Oxide in Trigeminal Neuralgia Rats with a Cerium Single-Atom Nanozyme Electrochemical Biosensor.
- Response to letter to the editor regarding "electrophysiological monitoring of the trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia".
- Letter to the editor regarding "Electrophysiological monitoring of the trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia".
- Chrono-anatomical precision in salvage therapy for recurrent trigeminal neuralgia: mechanistic insights and cost-utility analysis of percutaneous balloon compression.
- Demonstrating Petrous Dural Incision Technique for Vascular Releasing and Transposition of Dura-Embedded Subarcuate Loop of Anterior Inferior Cerebellar Artery During Retrosigmoid Approach.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:221091(Orphanet)
- OMIM OMIM:190400(OMIM)
- MONDO:0008599(MONDO)
- GARD:7805(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q1132120(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
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