Raras
Buscar doenças, sintomas, genes...
Angiosarcoma
ORPHA:263413CID-10 · C49.9CID-11 · 2B56DOENÇA RARA

Tumor maligno que surge das células endoteliais dos vasos sanguíneos. Microscopicamente, é caracterizado por canais vasculares frequentemente abertos, anastomosados ​​e ramificados. As células malignas que revestem os canais vasculares são fusiformes ou epitelióides e frequentemente apresentam núcleos hipercromáticos. Os angiossarcomas ocorrem com mais frequência na pele e na mama. Pacientes com linfedema de longa data apresentam risco aumentado de desenvolver angiossarcoma.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

Tumor maligno que surge das células endoteliais dos vasos sanguíneos. Microscopicamente, é caracterizado por canais vasculares frequentemente abertos, anastomosados ​​e ramificados. As células malignas que revestem os canais vasculares são fusiformes ou epitelióides e frequentemente apresentam núcleos hipercromáticos. Os angiossarcomas ocorrem com mais frequência na pele e na mama. Pacientes com linfedema de longa data apresentam risco aumentado de desenvolver angiossarcoma.

Pesquisas ativas
25 ensaios
103 total registrados no ClinicalTrials.gov
Publicações científicas
7.830 artigos
Último publicado: 2026

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
<1 / 1 000 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Europe
Início
Adult
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: C49.9
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🩸
Sangue
4 sintomas
🧬
Pele e cabelo
4 sintomas
🫃
Digestivo
3 sintomas
📏
Crescimento
1 sintomas
🛡️
Imunológico
1 sintomas
🦴
Ossos e articulações
1 sintomas

+ 10 sintomas em outras categorias

Características mais comuns

Anormalidade do baço
Perda de peso
Imunodeficiência
Anormalidade do membro inferior
Hemangioma
Bócio
27sintomas
Sem dados (27)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 27 características clínicas mais associadas, ordenadas por frequência.

Anormalidade do baçoAbnormality of the spleen
Perda de pesoWeight loss
ImunodeficiênciaImmunodeficiency
Anormalidade do membro inferiorAbnormality of the lower limb
Hemangioma

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico7.830PubMed
Últimos 10 anos200publicações
Pico2026101 papers
Linha do tempo
2026Hoje · 2026🧪 1995Primeiro ensaio clínico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 212
1Fase 13
·Pré-clínico5
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Angiosarcoma

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

15 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

103 ensaios clínicos encontrados, 25 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
🧪 Está conduzindo uma pesquisa?
Divulgue para pacientes e familiares que acompanham esta doença.
Divulgar pesquisa →

Publicações mais relevantes

📖Melhor nível de evidência: Revisão
Timeline de publicações
3.365 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 3.365

#1

Primary low-grade breast angiosarcoma initially misdiagnosed as a benign vascular lesion.

BMJ case reports2026 Mar 23

Primary breast angiosarcoma is an exceptionally rare malignancy, particularly in elderly patients, and may closely resemble benign vascular lesions on imaging and core needle biopsy. We report a case of low-grade primary angiosarcoma in a woman in her late 70s, initially misdiagnosed as a haemangioma despite interval tumour growth. A definitive diagnosis was achieved only after wide local excision, which demonstrated well to intermediately differentiated angiosarcoma with clear margins. Given the limited evidence supporting adjuvant therapy in low-grade disease, surgery alone was appropriate, and the patient remains recurrence-free at 2.5 years. This case highlights the diagnostic challenges and importance of maintaining suspicion in older adults.

#2

Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome.

Journal of clinical imaging science2026

Primary cerebellar angiosarcoma is an exceptionally rare intracranial malignancy, with only 22 cases reported in the literature. We report the case of a 67-year-old male who presented with a severe headache, unsteady gait, and giddiness. Computed tomography of the brain demonstrated a hemorrhagic lesion in the right cerebellar hemisphere with associated vasogenic edema and early hydrocephalus. Magnetic resonance imaging revealed a right cerebellar intra-axial lesion with mixed signal intensities and a characteristic peripheral "bull's eye" enhancement pattern. Histopathological evaluation showed a vasoformative neoplasm with atypical endothelial cells, high mitotic activity, and immunopositivity for CD31 and erythroblast transformation specific (ETS)-related gene (ERG), consistent with low-grade angiosarcoma. The patient underwent gross total resection and remained recurrence-free 16 months postoperatively. This case underscores the importance of multi-modality imaging in the early recognition of hemorrhagic cerebellar tumors and reinforces the role of radiological-pathological correlation in diagnosis and treatment planning. Given its rarity, diagnosis of cerebellar angiosarcoma requires a high index of suspicion, supported by advanced imaging and immunohistochemical profiling. Multidisciplinary management is essential, and further case documentation is necessary to guide therapeutic strategies and prognostication.

#3

Hepatic Angiosarcoma Associated with Chronic Schistosomiasis in a Patient with Decompensated Cirrhosis: A Rare Case Report.

Case reports in gastroenterology2026

Hepatic angiosarcoma (HA) is a rare endothelial malignancy with poor prognosis. Chronic Schistosoma infection causes periportal fibrosis and portal hypertension, but has not been established as a risk factor for hepatic vascular tumors. We report a case of high-grade HA coexisting with chronic schistosomiasis in a patient presenting with acute decompensated cirrhosis. A 64-year-old Filipino woman with no known chemical exposures presented with progressive abdominal pain, jaundice, ascites, and hepatic encephalopathy. Doppler ultrasound initially suggested Budd-Chiari syndrome, later excluded on advanced imaging. MRI showed multifocal hepatic lesions, and CT demonstrated multiple intra-abdominal hematomas without active bleeding. Liver biopsy confirmed poorly differentiated HA (CD31+/CD34+) and revealed calcified Schistosoma eggs. Her course was complicated by hemorrhagic shock after biopsy and paracentesis, spontaneous bacterial peritonitis, acute kidney injury, and worsening hepatic encephalopathy. She died despite aggressive supportive care. This case illustrates the diagnostic challenges and rapid progression of HA, especially in coagulopathic patients where biopsy carries significant risk. The coexistence of chronic schistosomiasis raises the possibility of parasitic inflammation contributing to hepatic vascular tumorigenesis. HA should be considered among unexplained hepatic masses with atypical imaging and clinical features.

#4

Primary splenic angiosarcoma with diffuse intrasinusoidal hepatic metastasis mimicking lymphoma: a diagnostic challenge.

Clinical journal of gastroenterology2026 Jan 13

Primary splenic angiosarcoma is a rare aggressive vascular neoplasm. Although hepatic metastases are common, diffuse intrasinusoidal hepatic involvement is extremely rare and poses a significant diagnostic challenge. A 60-year-old woman presented with bilateral lower extremity edema, hypoalbuminemia, and thrombocytopenia. Contrast-enhanced computed tomography revealed marked splenomegaly, but no distinct hepatic lesions. Gadoxetic acid-enhanced magnetic resonance imaging revealed reduced hepatic uptake without focal abnormalities. 1⁸F-fluorodeoxyglucose positron emission tomography-computed tomography revealed diffuse radiotracer uptake in both the liver and spleen, raising the suspicion of an infiltrative malignant process, such as lymphoma. Liver biopsy revealed sinusoidal infiltration by atypical cells positive for cluster of differentiation 31 and ETS-related gene, but lacked architectural features diagnostic of angiosarcoma. Due to diagnostic uncertainty and concerns regarding splenic rupture, splenectomy was performed. Histopathological examination confirmed a primary splenic angiosarcoma with diffuse intrasinusoidal hepatic metastasis. Primary splenic angiosarcoma rarely presents with non-nodular intrasinusoidal hepatic metastasis, mimicking infiltrative liver diseases. Liver biopsy may fail to yield a definitive diagnosis. Therefore, a splenectomy may be required to establish a definitive diagnosis and guiding appropriate management when liver biopsy is inconclusive. Recognizing this uncommon metastatic pattern is crucial to avoid misdiagnosis and ensure timely treatment.

#5

Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy.

BMJ case reports2026 Jan 06

Primary spinal angiosarcoma is extremely rare with few reported cases globally. While en bloc resection is the only definitive and curative treatment modality, this case highlights the potential for curative-intent, non-surgical management of spinal epithelioid angiosarcoma using taxane-based chemoradiotherapy, especially in anatomically challenging and surgically unresectable locations. It also emphasises the role of multimodal imaging and histopathological correlation in the diagnosis and monitoring of rare spinal tumours.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC5.021 artigos no totalmostrando 196

2026

Primary low-grade breast angiosarcoma initially misdiagnosed as a benign vascular lesion.

BMJ case reports
2026

Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma.

Oncoimmunology
2026

Primary cardiac angiosarcoma with isolated superior vena cava syndrome: a case report.

Journal of medical case reports
2026

Across borders and histologies: Rethinking endpoints for vascular sarcoma trials.

Clinical cancer research : an official journal of the American Association for Cancer Research
2026

Life-Threatening Lower GI Bleeding From Sigmoid Colon Metastasis of Cutaneous Angiosarcoma: A Case Report.

Cureus
2026

Nonconventional MYC-Positive Primary Cutaneous Angiosarcoma: Novel or Untested.

The American Journal of dermatopathology
2026

Revisiting the Immune Frontier in Soft Tissue Sarcomas.

Current oncology reports
2026

A rare pulmonary epithelioid angiosarcoma with ALK rearrangement: a case report and literature review.

Frontiers in oncology
2026

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications.

Head &amp; neck
2026

Atypical Postradiation Vascular Proliferation: A Rare Dermatologic Sequela of Breast Cancer Therapy.

Clinical breast cancer
2026

Radiation-Induced Angiosarcoma of the Breast With Diffuse GATA-3 Positivity: A Possible Diagnostic Pitfall.

The American Journal of dermatopathology
2026

Diagnosis and treatment of primary orbital angiosarcoma - a case study and review of the literature.

Orbit (Amsterdam, Netherlands)
2026

Overcoming Diagnostic and Therapeutic Challenges in Primary Cardiac Angiosarcoma.

JACC. Case reports
2026

Tissue Is Not the Only Issue in Multimodality, Multidisciplinary Cardiac Mass Evaluation.

JACC. Case reports
2026

Genome agnostic, multi-level non-oncogene addiction-based systems pharmacology for rescuing metastatic relapsed/refractory neoplasias.

Frontiers in pharmacology
2026

Rare Angiosarcoma in the Postauricular Region-A Diagnostic Challenge and Treatment.

Clinical case reports
2026

Anastomosing hemangioma of the renal pelvis: The first case report from Vietnam.

Urology case reports
2026

18F-FDG Outperforms 18F-FAPI-04 in Detecting Primary Splenic Angiosarcoma and Its Metastatic Lesions in Liver.

Clinical nuclear medicine
2026

Primary epithelioid angiosarcoma of the vulva: A rare tumor at an unusual site.

Rare tumors
2026

Radiation-Induced Angiosarcoma Following Breast Surgery: A Case Report.

Surgical case reports
2026

Primary Pericardial Angiosarcoma Demonstrating Initial Response Followed by Progression on First-Line Chemotherapy: A Case Report.

Clinical case reports
2026

A Rare Case of Primary Breast Angiosarcoma: Diagnostic Challenges and Findings.

Journal of clinical ultrasound : JCU
2026

Hemangiosarcoma: A Systematic Review of Biomarkers in Diagnosis, Prognosis, and Therapeutic Strategies.

Veterinary and comparative oncology
2026

Clinical Characteristics and Prognostic Factors of Renal Sarcoma: A Japanese National Cancer Registry Study.

Cancer investigation
2026

Efficacy and safety of pazopanib in patients with paclitaxel-pretreated primary cutaneous angiosarcoma in Japan: Results of the Japan Clinical Oncology Group single-arm confirmatory trial (JCOG1605).

The British journal of dermatology
2026

Evaluation of Radiotherapy Dose in Secondary Breast Angiosarcoma: Implications for Pathogenesis.

Anticancer research
2026

Large atypical cells with foamy cytoplasm in bone marrow in primary splenic angiosarcoma: a case report.

International journal of hematology
2026

Vascular bone tumors of the pelvis and extremities: an 18-case clinical and radiological analysis.

Archives of orthopaedic and trauma surgery
2026

Genomic Landscape and Therapeutic Implications of Metaplastic Breast Carcinoma: Insights from a Nationwide Database Including Diagnostic Mimickers.

Pharmaceuticals (Basel, Switzerland)
2026

Primary Angiosarcoma of Breast: Surgery Alone Versus Chemotherapy and/or Radiotherapy-A Systematic Review and Meta-Analysis.

Cancers
2026

Incidence and Survival of Thoracic Angiosarcoma: Epidemiologic Evidence from a Population-Based Cancer Registry.

Cancers
2026

Canonical microRNA loss drives tumor development implicating therapeutic efficacy of enoxacin in angiosarcoma.

RNA (New York, N.Y.)
2026

Expanded Radiologic Characterization and Long-Term Imaging Follow-Up of Sclerosing Angiomatoid Nodular Transformation (SANT): A Case Report.

Cureus
2026

An Atypical Presentation of Cutaneous Angiosarcoma: A Diagnostic Challenge in an End-Stage Renal Disease Patient.

Cureus
2026

Primary angiosarcoma of the seminal vesicle: a detailed case report and literature review of an extremely rare urological malignancy.

BMC urology
2025

Angiosarcoma Presenting as Hemifacial Edema.

Ophthalmic plastic and reconstructive surgery
2026

Silent Invader: The Enigmatic Case of Cardiac Angiosarcoma.

Cureus
2026

Postradiation angiosarcoma of the breast: a 25-year single-institution analysis of clinicopathological characteristics and immunohistochemical biomarker study.

Biotechnic &amp; histochemistry : official publication of the Biological Stain Commission
2026

Presentation, management, and outcomes of malignant vascular sarcomas: a National Cancer Database comparison of pediatrics and adults.

American journal of surgery
2026

Stewart-Treves syndrome: A fatal complication of rheumatoid arthritis-associated massive lymphedema.

JAAD case reports
2026

Right Atrial Mass in a 63-Year-Old Woman.

Chest
2026

Low Subcutaneous Adipose Tissue is Associated with Poor Prognosis for Aged Patients with Cutaneous Angiosarcoma: A Retrospective Cohort Study.

Acta dermato-venereologica
2026

Unique advantages of contrast-enhanced ultrasound in identifying extremely rare hepatic angiosarcoma with sinusoidal growth patterns.

Quantitative imaging in medicine and surgery
2026

Right Atrial Angiosarcoma Presenting With Cardiac Tamponade, Hemorrhagic Pericardial Effusion, and Pulmonary Embolism: A Case Report.

Cureus
2026

Multidisciplinary Management of a Rare Primary Cardiac Angiosarcoma.

JACC. Case reports
2026

Post-Traumatic Intravascular Papillary Endothelial Hyperplasia (Masson Tumor) of the Eyelid.

The Journal of craniofacial surgery
2026

Customized Non-invasive Brachytherapy With Tailored Surface Moulds: An Experience From a Tertiary Care Centre.

Clinical oncology (Royal College of Radiologists (Great Britain))
2026

The anti-apoptotic protein lifeguard is expressed in osteosarcoma, chondrosarcoma and soft tissue sarcoma.

Oncology
2026

Clinicopathological features and survival disparities between axial and appendicular skeletal Angiosarcoma: A SEER-based analysis using competing risk models.

Journal of bone oncology
2026

Primary renal angiosarcoma with renal vein thrombus: Case report and Review of literature.

Urology case reports
2026

Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome.

Journal of clinical imaging science
2026

Treatment Beyond Progressive Disease With Pazopanib for Cutaneous Angiosarcoma: A Case Report.

The Journal of dermatology
2026

Circumferential Resection of the Right Atrium to Excise Angiosarcoma.

JACC. Case reports
2025

Hepatic Angiosarcoma Mimicking Sinusoidal Obstruction Syndrome: A Case Report.

Cureus
2026

Malignant vascular neoplasms of the distal female genital tract: a series of 19 cases emphasizing unusual features and diagnostic challenges.

Histopathology
2026

Primary Hepatic Angiosarcoma: Distinct Imaging Phenotypes Mirroring Histopathologic Growth Patterns in a Retrospective Human Study.

Diagnostics (Basel, Switzerland)
2026

Selective MYC 5' amplification in postirradiation/lymphedema-associated angiosarcoma.

Virchows Archiv : an international journal of pathology
2026

Hepatic Angiosarcoma Associated with Chronic Schistosomiasis in a Patient with Decompensated Cirrhosis: A Rare Case Report.

Case reports in gastroenterology
2025

Hypopyon Sign in Acral Lesions: Dermoscopic Findings of a Patient with Palmoplantar Pustulosis.

Current health sciences journal
2026

Awake mastectomy in a patient with severe cardio-respiratory disease.

Anaesthesia reports
2026

Diagnostic Utility of Contrast-Enhanced Ultrasound and Multimodal Imaging in Splenic Angiosarcoma: A Pathologically Confirmed Case Report.

Journal of clinical ultrasound : JCU
2026

Phase II trial, multicenter, first-line paclitaxel-avelumab treatment of inoperable angiosarcoma (KCSG UN 18-15).

ESMO open
2025

Primary epithelioid angiosarcoma of the jejunum presenting with severe anemia and distant metastasis: a case report and literature review.

Frontiers in oncology
2026

Breast Hemangioma with Slow Growth over 11 Years: A Case Report.

Reports (MDPI)
2025

Exploring the enigma within: a retrospective study of primary cardiac sarcomas from a tertiary care centre.

Ecancermedicalscience
2026

Atypical Vulvovaginal Postradiation Vascular Lesion: A Distinctive, Benign Mimic of Angiosarcoma Characterized in a Series of 15 Patients.

The American journal of surgical pathology
2026

Primary aortic angiosarcoma following endovascular aneurysm repair: Case report and review of the literature.

Journal of vascular surgery cases and innovative techniques
2026

A rare vascular puzzle: Portal hypertension and hepatic lesions.

Journal of hepatology
2025

[Radiation-Associated Angiosarcoma of the Breast-A Case Report].

Gan to kagaku ryoho. Cancer &amp; chemotherapy
2025

One case of left atrial arterial intimal sarcoma.

International journal of surgery case reports
2026

Angiosarcoma developing in an ovarian fibroma: A case report.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia
2026

Clinical and Pathological Significance of GLUT-1 Expression in Angiosarcoma and Other Vascular Tumors.

The Journal of dermatology
2026

Primary splenic angiosarcoma with diffuse intrasinusoidal hepatic metastasis mimicking lymphoma: a diagnostic challenge.

Clinical journal of gastroenterology
2026

Surgical resection of a primary cardiac angiosarcoma and reconstruction of involved right atrium.

Journal of surgical case reports
2026

Advances in Clinical Trials of Boron Neutron Capture Therapy.

Research (Washington, D.C.)
2026

CT findings of primary hepatic angiosarcoma complicated with hepatic sinusoidal obstruction syndrome: a case description.

Quantitative imaging in medicine and surgery
2026

Diagnosis, treatment, and prognosis of scalp angiosarcoma: A case report.

Medicine
2026

Contributors of All-Causes Mortality in Patients With Primary and Secondary Cutaneous Angiosarcoma.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
2026

Multimodal Therapy in Cutaneous Angiosarcoma: A National Cancer Database Study of Treatment Patterns and Survival.

Annals of surgical oncology
2025

Adult urologic sarcomas: a single institution experience over 25 years.

The Canadian journal of urology
2026

Multimodal treatment of radiation-associated laryngeal angiosarcoma: A case report and literature review.

Medicine
2026

Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy.

BMJ case reports
2026

Cardiac epithelioid hemangioendothelioma with WWTR1::ACTL6A fusion and atypical histology mimicking cardiac angiosarcoma.

Histopathology
2025

Pseudoangiomatous Stromal Hyperplasia in the Breast: A Report of a Rare Case.

Cureus
2026

Congenital lumbosacral meningocele with malignant transformation to epithelioid angiosarcoma: A case report of complex spinal anomalies.

Radiology case reports
2025

Primary Angiosarcoma of Bone of the Skull Base: A Case Report and Literature Review.

Cureus
2026

Atypical presentation of angiosarcoma detected by 18F-FDG PET/CT as a solitary mediastinal lesion.

Revista espanola de medicina nuclear e imagen molecular
2026

Peritoneal Post-Radiation Angiosarcoma in a Patient With a History of Radiation for Cervical Cancer.

The American journal of case reports
2026

A Phase 2 Study of the Eribulin in Patients with Metastatic Angiosarcoma and Epithelioid Hemangioendothelioma (EHE).

Clinical cancer research : an official journal of the American Association for Cancer Research
2026

Five Cases of Hepatic Mesenchymal Tumors Diagnosed by Endoscopic Ultrasound-Guided Tissue Acquisition.

DEN open
2025

Preoperative Embolization for Sinonasal Angiosarcoma Optimized Intraoperative and Postoperative Outcomes: A Case Report.

The Annals of otology, rhinology, and laryngology
2025

Nasal Angiosarcoma Mimicking Common Sinonasal Tumors.

The Journal of craniofacial surgery
2025

Primary Cardiac Sarcomas: Clinical Characteristics, Management, and Outcomes at a Spanish National Reference Center.

Cancers
2026

Angiosarcoma Arising in 1 of 2 Adolescent Twins With Cryptogenic Cirrhosis and MAF Gene Mutation.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
2025

Diagnostic pitfalls: soft-tissue sarcomas initially misdiagnosed as benign vascular anomalies-a case report and systematic review.

Oncology reviews
2025

Primary adrenal angiosarcoma: a rare case presentation.

Journal of surgical case reports
2025

Recent advances in chemotherapy and targeted therapies for breast sarcoma.

Expert review of anticancer therapy
2026

Thyroid angiosarcoma: a comprehensive review.

Seminars in diagnostic pathology
2025

Cardiac Angiosarcoma as an Unexpected Cause of Palpitations: Case Report, Differential Diagnosis, and Current Therapeutic Approach to Cardiac Tumors.

Cureus
2025

RESOLVING DIFFICULT HISTOLOGICAL DIAGNOSIS OF THE RARE ACANTHOLYTIC SQUAMOUS CELL CARCINOMA USING IMMUNOHISTOCHEMISTRY: A CASE REPORT.

Annals of Ibadan postgraduate medicine
2025

The "silent assassin" of the liver: angiosarcoma with portal hypertension.

Medical ultrasonography
2025

Radiation-Induced Epithelioid Angiosarcoma of the Urinary Bladder Mimicking Sarcomatoid Carcinoma: A Rare Entity and Literature Review.

International journal of surgical pathology
2025

Aristolochic Acid and Alternative Lengthening of Telomeres Mechanisms Underlie Liver Angiosarcoma Pathogenesis.

Liver cancer
2025

Left Atrial Epithelioid Angiosarcoma Presenting As Recurrent Stroke: A Case Report.

Cureus
2025

Imaging approach to retroperitoneal vascular tumors: a narrative review.

Abdominal radiology (New York)
2025

Concomitant gastric carcinoma and primary hepatic angiosarcoma in a patient: A case report.

Open life sciences
2025

The diagnostic dilemma of sinusoidal-type primary hepatic angiosarcoma: A case report and literature review.

Frontiers in oncology
2025

Angiomatosis of the Breast: Unveiling a Rare and Unusual Vascular Puzzle.

Cureus
2025

Malignant Right Atrial Mass With Inferior Vena Cava Extension Presenting as Budd-Chiari Syndrome: A Multimodality Imaging Case Report.

Cureus
2026

Evolution of retiform hemangioendothelioma into angiosarcoma.

JAAD case reports
2026

99m Tc-RBC SPECT/CT Scintigraphy for Diagnosis of Small Intestinal Angiosarcoma : A Case Report.

Clinical nuclear medicine
2025

Cardiac Angiosarcoma With Lung Metastasis Presenting as Granuloma-Like Lesions: One Case Report and Literature Review.

Respirology case reports
2025

Multiple Pulmonary Cavernous Hemangioma: A Case Report.

Surgical case reports
2025

Primary breast angiosarcoma with diagnostic pitfalls and management challenges.

BMJ case reports
2025

Spontaneous hepatic rupture: A catastrophic complication in a patient with primary splenic angiosarcoma and hepatic metastasis: case report and literature review.

Frontiers in oncology
2025

Signet ring cell cutaneous angiosarcoma with ATM deletion mutation on scalp.

JAAD case reports
2026

Potential characteristic image findings of primary angiosarcoma of the breast: A case report.

Radiology case reports
2026

Primary Epithelioid Angiosarcoma of the Penis With Aberrant Expression of Synaptophysin: A Case Report and Review of Diagnostic Pitfalls.

Journal of cutaneous pathology
2025

Molecular Characterization of Primary Ovarian Angiosarcoma in a Patient With a History of Mature Ovarian Teratoma.

Cureus
2025

Primary Cardiac Osteosarcoma: Epidemiology, Diagnosis, and Management - A Narrative Review.

Orthopedic reviews
2025

Genomic and Demographic Characteristics of Angiosarcoma as Described in the AACR Project GENIE Registry.

Cancers
2025

Primary non-Hodgkin's lymphoma of the right atrium presenting as a cardiac mass: surgical debulking followed by chemotherapy.

Indian journal of thoracic and cardiovascular surgery
2025

Clinicopathological Features and Therapeutic Outcomes of Head and Neck Sarcomas: A 14-Year Retrospective Study.

Cureus
2025

Rare Indications of Splenectomy: A Case Series and Literature Review.

Cureus
2025

Primary cerebellar angiosarcoma: a rare case report and literature review.

BMC surgery
2025

A Case Report of Surgical and Postoperative Treatment for Thyroid Angiosarcoma with Pulmonary Metastasis.

Surgical case reports
2025

Soft-Tissue Chest Wall Reconstruction for Secondary Angiosarcoma: Systematic Review and Case Series.

Annals of plastic surgery
2026

A Discovery of Potentially Hereditary Cardiac Angiosarcoma.

JACC. Case reports
2025

Utility of 18F-FDG PET/CT for diagnosing and staging solitary malignant tumors of the spleen.

Frontiers in medicine
2025

Sarcoma: Cardiovascular and Oncologic Considerations: JACC: CardioOncology State-of-the-Art Review.

JACC. CardioOncology
2025

Multi-omics analysis revealed potential use of immunotherapy and CDK4/6 inhibitors in intimal sarcoma.

Frontiers in immunology
2025

Concurrent MYC-Amplified Secondary Angiosarcoma and Recurrent Carcinoma in the Breast: A Rare Presentation With Unique Clinical Features and Distinct MYC Amplification Patterns.

International journal of surgical pathology
2026

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets.

Oncology letters
2025

Multidisciplinary treatment for primary cardiac angiosarcoma: a case report and overview of the literature.

BMC cardiovascular disorders
2025

Seeking out the primary tumour: multi-modality imaging of metastatic cardiac angiosarcoma.

European heart journal. Imaging methods and practice
2026

Myeloid Sarcoma Versus Epithelioid Angiosarcoma: A Case Report of a Potential Diagnostic Pitfall.

International journal of surgical pathology
2025

Splenic angiosarcoma with hepatic and cardiac metastases: a case report and literature review.

Frontiers in oncology
2026

Secondary Lower-Body Sarcomas in Cervical Cancer Survivors Following Surgery, Radiotherapy, or Both: A Population-Based Study.

Cancer science
2025

[Primary duodenal epithelioid angiosarcoma:a case report].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
2025

Primary Pulmonary Epithelioid Angiosarcoma With Partial Response to Paclitaxel Treatment: A Case Report.

Cureus
2025

Cutaneous Angiosarcoma Mimicking Masson's Tumor in an Elderly Male: A Diagnostic Challenge and Treatment Failure.

Cureus
2025

Ravulizumab as an alternative for gemcitabine related trombotic microangiopathy: A case report.

Nefrologia
2025

Correspondence: Prognostic significance of positive surgical margins for scalp angiosarcoma.

Journal of the Formosan Medical Association = Taiwan yi zhi
2025

Radiation-induced angiosarcoma of the breast - experience from clinical practice.

Ceska gynekologie
2025

Pulmonary artery angiosarcoma.

Thorax
2026

An exceedingly rare case of de novo hepatic angiosarcoma in a transplanted liver.

Radiology case reports
2025

Simply the (B)EST: what the interventionalist needs to know about (bleomycin) electrosclerotherapy for vascular anomalies.

European radiology
2025

Acute rupture of primary hepatic angiosarcoma with Kasabach-Merritt syndrome: a rare case report and literature review.

World journal of surgical oncology
2026

Primary epithelioid angiosarcoma of the liver.

Clinical journal of gastroenterology
2025

High-Grade Angiosarcoma Transformation in Schwannoma and SMARCB1 Mutation: A Case Report.

The American journal of case reports
2025

Characteristics, Outcomes, and Risk Factors in Primary and Secondary Angiosarcoma: A Retrospective Cohort Study.

The breast journal
2026

Clinicopathologic and radio-genomic insights into hepatic epithelioid hemangioma: An illustrated review.

Human pathology
2025

The RANK-RANKL-OPG axis in dermatological malignancies: A systematic review.

International immunopharmacology
2025

Angiosarcoma Revisited: Diagnostic Challenges and a 16-Year Retrospective Analysis from a Single Institution.

Iranian journal of pathology
2025

Novel Therapeutic Approaches for Cutaneous Angiosarcoma, Particularly Focusing on Immune Checkpoint Inhibitors.

Cancers
2025

Pulmonary metastatic paraganglioma with angiosarcomatous differentiation: a rare case report and literature review.

The Pan African medical journal
2026

Intravascular organizing thrombus in the forearm: a unique imaging presentation.

Skeletal radiology
2025

Contrast-Enhanced Ultrasound-Guided Liver Tumor Biopsy for Primary Hepatic Angiosarcoma: A Case Series.

Cureus
2025

Destructive upper limb malignant ulcer: A case report of angiosarcoma.

International journal of surgery case reports
2025

ANGIOSARCOMA ASSOCIATED WITH RADIATION THERAPY IN PATIENTS WITH A HISTORY OF INVASIVE BREAST CARCINOMA. A CASE REPORT AND REVIEW OF THE LITERATURE.

Experimental oncology
2026

Primary Uterine Angiosarcoma Presenting With Omental Metastasis, Lymph Node Involvement, and Demonstrating a Null p53 Mutational Staining Pattern.

International journal of surgical pathology
2025

Diffuse Alveolar Haemorrhage Complicated by Pulmonary Metastasis of Cardiac Angiosarcoma and Kasabach-Merritt Syndrome: A Case Report.

Respirology case reports
2025

Efficacy and Safety of Helical Tomotherapy Combined With Paclitaxel in Cutaneous Angiosarcoma.

The Journal of dermatology
2025

Primary Breast Angiosarcoma: A Case Report.

Cureus
2025

Primary cardiac angiosarcoma with right atrial rupture.

Interdisciplinary cardiovascular and thoracic surgery
2025

A synthetic cohort analysis of postoperative management of primary cardiac angiosarcoma and a case report.

Frontiers in oncology
2026

Sinonasal Sarcomas Management: An International Consensus Statement.

International forum of allergy &amp; rhinology
2025

Vaccination Against Extracellular Vimentin Plus Doxorubicin for Canine Hemangiosarcoma.

International journal of molecular sciences
2025

Triangulating Timing, Tropism and Burden of Sarcoma Metastases: Toward Precision Surveillance and Therapy in a Real-World-Time Cohort.

Cancers
2025

Plasminogen Activator Inhibitor-1 in Skin Malignancies: Therapeutic Implications of Its Inhibition.

Biomolecules
2025

PAI-1 in Skin Malignancies: a Central Regulator of Tumor Progression and Therapeutic Resistance.

Current treatment options in oncology
2025

Radiation-Associated Breast Angiosarcoma Versus Recurrent Invasive Ductal Carcinoma After Partial Mastectomy: A Diagnostic Dilemma.

Clinical case reports
2025

Multimodal Imaging in the Diagnosis of Primary Aortic Epithelioid Angiosarcoma.

Cureus
2025

Survival Outcomes in Cutaneous Angiosarcoma: A Meta Analysis.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
2025

Outcome of 1773 superficial non-dermatofibrosarcoma sarcomas A French Sarcoma Group study (FSG) from the NETSARC database.

European journal of cancer (Oxford, England : 1990)
2025

[Vascular neoplasms of the liver].

Pathologie (Heidelberg, Germany)
2025

A case of cutaneous angiosarcoma with intradermal metastases responding to PD-1 inhibition-based immunotherapy.

JAAD case reports
2025

Immunotherapy and Targeted Therapies in Sarcoma: Proposed Synergy with Combination Treatment.

Journal of immunotherapy and precision oncology
2025

Rare Metastases to Liver and Spleen form a Seldom Case of Facial Angiosarcoma Demonstrated on Staging FDG PET-CT.

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
2026

Split Facies with Destructive and Leonine Appearance: An Atypical Presentation of Angiosarcoma.

Indian dermatology online journal
2025

Intramuscular hematomas as the first presentation of angiosarcoma.

Polish archives of internal medicine
2025

Preclinical Investigations Toward Gd-free Molecularly Targeted Dual-Modal, MRI Dynamic (DCE-MRI)/Optical Imaging Contrast Agent for Cardiac Angiosarcoma.

Topics in magnetic resonance imaging : TMRI
2026

Comparison of clinical features between patients with bone and soft tissue angiosarcomas.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
2025

Outcome of systemic therapy in patients with advanced rare skin cancers: A retrospective multicenter DeCOG study of 209 patients.

European journal of cancer (Oxford, England : 1990)
2025

Updating the genomic and clinicopathologic features of thoracic SMARCA4-deficient undifferentiated tumor: a mini-series including a long-term survivor.

Frontiers in oncology
2025

Case Report: Hepatic infantile hemangioma malignantly transformed into hemangiosarcoma.

Frontiers in oncology
2025

Brain Metastasis From Angiosarcoma of the Scalp: Report of Three Cases.

The Journal of dermatology
2025

Comparison of 68Ga-FAPI-04 and 18F-FDG in Primary Splenic Angiosarcoma.

Clinical nuclear medicine
2026

Diffuse Cutaneous Angiosarcoma Involving Scalp and Face on 18 F-FDG and 68 Ga-NODAGA-RGD PET/CT.

Clinical nuclear medicine
2025

Pulmonary angiosarcoma in an HIV-positive patient presenting with hemoptysis and multisystem involvement: Report of a rare case.

Medicine international
2025

Cardiac Angiosarcoma in a 17-Year-Old Female: A Rare Case Report and Literature Review.

Cureus
2025

Secondary Angiosarcoma of the Thigh Arising From Lymphedema After Post-Operative Radiotherapy for Extramammary Paget's Disease: A Case Report.

The Journal of dermatology
2025

Coexistence of a Rare Giant Right Ventricular Angiosarcoma with Right Coronary Artery Pseudoaneurysm and Unilateral Pleural Effusion: A Case Report.

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
2025

Splenic hamartoma mimicking angiosarcoma: A case report.

World journal of clinical cases
2025

Primary Jejunal Angiosarcoma.

ACG case reports journal
2025

Primary pulmonary artery sarcoma treated with simultaneous pulmonary valve replacement, artificial vessel replacement, and total right pneumonectomy: a case report.

General thoracic and cardiovascular surgery cases
Ver todos os 5.021 no EuropePMC

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

Ainda não temos associações cadastradas para Angiosarcoma.

É de uma associação que acompanha esta doença? Fale com a gente →

Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

Ainda não existe comunidade no Raras para Angiosarcoma

Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.

Tire suas dúvidas

Perguntas, dicas e experiências compartilhadas aqui na página

Participe da discussão

Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.

Fazer login

Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Primary low-grade breast angiosarcoma initially misdiagnosed as a benign vascular lesion.
    BMJ case reports· 2026· PMID 41871903mais citado
  2. Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome.
    Journal of clinical imaging science· 2026· PMID 41624477mais citado
  3. Hepatic Angiosarcoma Associated with Chronic Schistosomiasis in a Patient with Decompensated Cirrhosis: A Rare Case Report.
    Case reports in gastroenterology· 2026· PMID 41586403mais citado
  4. Primary splenic angiosarcoma with diffuse intrasinusoidal hepatic metastasis mimicking lymphoma: a diagnostic challenge.
    Clinical journal of gastroenterology· 2026· PMID 41528423mais citado
  5. Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy.
    BMJ case reports· 2026· PMID 41494718mais citado
  6. Case Report of Primary Splenic Angiosarcoma in a Young Patient: A Very Rare and Challenging Disease.
    Case Rep Surg· 2026· PMID 41994302recente
  7. Breast Angiosarcoma: 15-Years Experience.
    ANZ J Surg· 2026· PMID 41992621recente
  8. Liposomal Versus Conventional Doxorubicin as First-Line Therapy in Advanced Soft Tissue Sarcomas: Observational Multi-Institutional Cohort of 8.5-Year Experience.
    JCO Oncol Pract· 2026· PMID 41990299recente
  9. Surgical Management of Primary and Metastatic Cardiac Malignancies: A 20-Year Single-Center Experience.
    Ann Thorac Cardiovasc Surg· 2026· PMID 41987379recente
  10. Diagnostic Pitfalls and Imaging-Pathologic Correlation in Benign Breast Vascular Lesions Mimicking Malignancy: A Case-Based Systematic Review.
    Am Surg· 2026· PMID 41983940recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:263413(Orphanet)
  2. MONDO:0016982(MONDO)
  3. GARD:20900(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q2619091(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Angiosarcoma
Compêndio · Raras BR

Angiosarcoma

ORPHA:263413 · MONDO:0016982
Prevalência
<1 / 1 000 000
Herança
Not applicable
CID-10
C49.9 · Neoplasia maligna do tecido conjuntivo e tecidos moles, não especificados
CID-11
Ensaios
25 ativos
Início
Adult
Prevalência
0.0 (Europe)
MedGen
UMLS
C0018923
EuropePMC
Wikidata
Wikipedia
Papers 10a
DiscussaoAtiva

Nenhuma novidade ainda. O agente esta monitorando.

0membros
0novidades