Raras
Buscar doenças, sintomas, genes...
Sarcoma de Kaposi
ORPHA:33276CID-10 · C46.0CID-11 · 1C60.30DOENÇA RARA

É um câncer que se caracteriza por um crescimento de vasos sanguíneos, os quais geralmente contêm células arredondadas. É comum haver vazamento de glóbulos vermelhos e acúmulo de hemossiderina, uma substância amarronzada que se forma a partir do sangue. O local mais frequente onde aparece é a pele, mas também pode surgir em órgãos internos. Geralmente se desenvolve em pessoas com o sistema imunológico enfraquecido, incluindo aquelas com a síndrome da imunodeficiência adquirida (AIDS).

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

É um câncer que se caracteriza por um crescimento de vasos sanguíneos, os quais geralmente contêm células arredondadas. É comum haver vazamento de glóbulos vermelhos e acúmulo de hemossiderina, uma substância amarronzada que se forma a partir do sangue. O local mais frequente onde aparece é a pele, mas também pode surgir em órgãos internos. Geralmente se desenvolve em pessoas com o sistema imunológico enfraquecido, incluindo aquelas com a síndrome da imunodeficiência adquirida (AIDS).

Pesquisas ativas
25 ensaios
177 total registrados no ClinicalTrials.gov
Publicações científicas
4.179 artigos
Último publicado: 2026 Apr 7

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-9 / 100 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Europe
Início
Adult
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: C46.0
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧬
Pele e cabelo
4 sintomas
🩸
Sangue
4 sintomas
🫃
Digestivo
3 sintomas
🦴
Ossos e articulações
1 sintomas
🛡️
Imunológico
1 sintomas
📏
Crescimento
1 sintomas

+ 9 sintomas em outras categorias

Características mais comuns

100%prev.
Herpes recorrente
90%prev.
Anormalidade do membro inferior
Muito frequente (99-80%)
90%prev.
Neoplasia da pele
Muito frequente (99-80%)
90%prev.
Mácula hiperpigmentada
Muito frequente (99-80%)
90%prev.
Mácula
Muito frequente (99-80%)
55%prev.
Hemangioma
Frequente (79-30%)
26sintomas
Muito frequente (5)
Frequente (10)
Ocasional (11)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 26 características clínicas mais associadas, ordenadas por frequência.

Herpes recorrenteRecurrent herpes
Muito frequente100%
Anormalidade do membro inferiorAbnormality of the lower limb
Muito frequente (99-80%)90%
Neoplasia da peleNeoplasm of the skin
Muito frequente (99-80%)90%
Mácula hiperpigmentadaHypermelanotic macule
Muito frequente (99-80%)90%
MáculaMacule
Muito frequente (99-80%)90%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico4.179PubMed
Últimos 10 anos200publicações
Pico2025124 papers
Linha do tempo
2026Hoje · 2026🧪 1992Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 28
1Fase 15
·Pré-clínico7
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Sarcoma de Kaposi

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

15 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

177 ensaios clínicos encontrados, 25 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
2.035 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 2.035

#1

Mogamulizumab-Associated Kaposi Sarcoma in 2 Patients With Primary Cutaneous T-Cell Lymphomas.

JAMA dermatology2026 Feb 11

This case report describes mogamulizumab-associated Kaposi sarcoma in 2 patients with primary cutaneous T-cell lymphomas.

#2

Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL.

PLoS pathogens2026 Jan

Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic virus that causes Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease. A vaccine that prevents KSHV infection or serves in the treatment of KSHV-related diseases represents a critical unmet need, however, the types of immune responses a vaccine should elicit have not been well defined. The gH/gL glycoprotein complex is an important target of KSHV-neutralizing antibodies, but the epitope specificities targeted by these antibodies remain unknown. Here, we isolated 12 gH/gL-specific monoclonal antibodies (mAbs) from KSHV-infected donors and performed structure/function analyses. These mAbs bind recombinant gH/gL with nanomolar affinities and epitope binning analyses revealed that the mAbs bind to 5 epitope clusters on gH/gL. Seven mAbs were able to neutralize KSHV infection of epithelial cell lines. Two potent neutralizing mAbs mapped to the EphA2 binding site as determined by inhibition of the receptor-ligand interaction and negative stain electron microscopy (nsEM) of the mAb/gH/gL complex. The epitopes of other neutralizing mAbs targeting novel sites of vulnerability were determined by a combination of cryogenic electron microscopy and nsEM. Together, these mAbs help to define the relevant epitope targets for KSHV vaccine design, have utility in understanding the role of antibodies in preventing KSHV infection, enable the development of immunotherapy approaches, and provide valuable tools to understand the molecular details of the KSHV entry process.

#3

Correction: Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo.

PLoS pathogens2026 Jan

[This corrects the article DOI: 10.1371/journal.ppat.1004581.].

#4

A viral Achilles' heel for EBV-positive lymphomas.

Blood2026 Feb 19
#5

Obscure Small Bowel Bleeding From Visceral Kaposi Sarcoma Without Cutaneous Manifestations.

The American journal of gastroenterology2026 Jan 01

Publicações recentes

Ver todas no PubMed

📚 EuropePMC2.152 artigos no totalmostrando 196

2026

Spatiotemporal patterns of AIDS and non-AIDS defining cancers before and after antiretroviral therapy rollout in Botswana, 1990-2021.

Cancer epidemiology, biomarkers &amp; prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
2026

Angiomatous Subtype of Penile Kaposi Sarcoma With Concurrent HIV-Negative Multicentric Castleman Disease: A Case Report.

International journal of surgical pathology
2026

Topical delivery of Vismodegib using fourth-generation PAMAM dendrimers: a potential treatment for Kaposi's sarcoma.

International journal of pharmaceutics
2026

Bilateral Necrotic Foot Lesions of Kaposi Sarcoma in a Man from Ecuador.

The American journal of tropical medicine and hygiene
2026

Artificial Intelligence-Based Diagnosis of Kaposi Sarcoma Using Digital Photographs in Dark-Skinned Patients in Uganda.

JCO global oncology
2026

Kaposi sarcoma herpesvirus (KSHV) subtypes and impact on outcomes in KSHV-associated diseases.

The Journal of infectious diseases
2026

Role of Oncoviruses in Cancer Progression and Emerging Phytochemical-Based Therapies from Medicinal Plants.

Molecular biotechnology
2026

Associations of Social and Demographic Factors on the Outcomes of Ocular Melanoma and Other Adult Ocular Neoplasms in the United States: A Systematic Review.

Cochrane evidence synthesis and methods
2026

Disseminated iatrogenic upper gastrointestinal Kaposi sarcoma following prolonged steroid use in a patients with Crohn's disease: a case report.

Journal of medical case reports
2026

Development and Validation of Claims-Based Algorithms for Non-Melanoma Skin Cancer in Patients With Psoriasis Using Optum Market Clarity.

Pharmacoepidemiology and drug safety
2026

Kaposi's Sarcoma in a Kidney Transplant Recipient: A Case Report on Paclitaxel Response.

Case reports in oncology
2026

Concurrent Monkeypox, HHV8, and Other Opportunistic Infections in a Human Immunodeficiency Virus Patient with Disseminated Kaposi Sarcoma: A Case Report.

Case reports in oncology
2026

Spatial and bulk transcriptomics reveal distinct molecular signatures in Kaposi sarcoma with and without other KSHV-associated diseases.

Journal of translational medicine
2026

Association between KSHV genotype and immune response to Kaposi sarcoma.

Human pathology
2026

Incidence of Cancers Among Children Living With HIV in Malawi After Widespread Availability of Antiretroviral Therapy: A Population-Based Study.

JCO global oncology
2026

Visceral leishmaniasis clinically disguised as Kaposi's sarcoma: a diagnostic challenge in people living with HIV.

Infection
2025

Isolated Gastrointestinal Kaposi's Sarcoma: A Case Report.

Journal of community hospital internal medicine perspectives
2026

Kaposi Sarcoma-Associated Herpesvirus Infection and Complications Among Solid Organ Transplant Recipients - United States, January 2021-September 2025.

MMWR. Morbidity and mortality weekly report
2026

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

The Journal of allergy and clinical immunology
2026

Classic Kaposi sarcoma of the upper limb secondary to lymphedema successfully treated with Nd:YAG laser.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
2026

A Retrospective Cohort Study on HHV-8 Viral Load and Prognosis in HIV-Associated Kaposi Sarcoma Among People Living with HIV in Japan.

Viruses
2026

Single-fraction low-energy superficial x-ray radiation for conjunctiva Kaposi sarcoma: A case report.

Archivos de la Sociedad Espanola de Oftalmologia
2026

Are Corticosteroids Truly Contraindicated in Pulmonary Kaposi Sarcoma?

Cureus
2025

Rapidly progressing Kaposi sarcoma in a human immunodeficiency virus-negative patient.

Dermatology online journal
2026

Patient- and caregiver-reported barriers to radiotherapy for cancer in sub-Saharan Africa-A survey of population-based registries.

International journal of cancer
2026

β-catenin: A crucial transcriptional activator of KSHV latency genes and small molecule target in primary effusion lymphoma.

Virology
2026

A viral Achilles' heel for EBV-positive lymphomas.

Blood
2025

Oral T-cell Non-Hodgkin's lymphoma in an HIV-positive patient: A rare case emphasizing the diagnostic value of immunohistochemistry.

Journal of oral and maxillofacial pathology : JOMFP
2025

Challenges in delineating B-cell lymphoma: A case of plasmablastic lymphoma mimicking Burkitt lymphoma.

Journal of oral and maxillofacial pathology : JOMFP
2026

Crocin Modulates AKT/mTORC1/ULK1 Cascade to Attenuate Ferritinophagy-Induced Colonic Oxidative Injury in Ulcerative Colitis: Network Pharmacology, Molecular Docking, and Experimental Validation.

Phytotherapy research : PTR
2026

The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion.

bioRxiv : the preprint server for biology
2026

Gastroduodenal Kaposi Sarcoma Without Cutaneous Lesions in an Immunosuppressed Patient.

Cureus
2026

Mogamulizumab-Associated Kaposi Sarcoma in 2 Patients With Primary Cutaneous T-Cell Lymphomas.

JAMA dermatology
2026

Upper Airway Obstruction due to Kaposi Sarcoma-Presenting Sign of HIV: Case Report and Review.

The Laryngoscope
2026

Kaposi sarcoma in plain sight: A solitary nasal papule in well-controlled HIV.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2025

Disseminated Kaposi sarcoma with cutaneous lesions on a surgical scar in a kidney transplant recipient.

Indian journal of dermatology, venereology and leprology
2026

Disseminated Kaposi Sarcoma With Gastrointestinal Involvement and Primary Effusion Lymphoma in an Untreated HIV Patient: A Case Report.

Cureus
2026

Disseminated classic Kaposi Sarcoma.

Clinical and experimental dermatology
2026

Kaposi Sarcoma in an Allograft Kidney Presenting as Acute Kidney Injury With No Cutaneous Lesions: A Case Report.

Cureus
2026

Reflecting on the potential impact of donor-derived Kaposi sarcoma in lung transplantation.

JHLT open
2026

HHV-8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions.

Transplant infectious disease : an official journal of the Transplantation Society
2026

Noncutaneous Visceral Kaposi Sarcoma of the Stomach and Liver: A Case Report.

Case reports in oncology
2026

Malignant vascular neoplasms of the distal female genital tract: a series of 19 cases emphasizing unusual features and diagnostic challenges.

Histopathology
2026

Kaposi Sarcoma of the Larynx.

Mayo Clinic proceedings
2026

Kaposi Sarcoma: Retrospective Clinical Analysis with a Focus on Age and HIV Serostatus.

Viruses
2026

HDR Brachytherapy in the Treatment of Skin Kaposi Sarcoma: A Mono-Institutional Series.

Cancers
2026

The Changing Face of HIV-Associated Malignancies: Is this the Same in Turkey As Well?

Current HIV research
2026

Improved screening for pulmonary Kaposi sarcoma in a low-resource setting.

AIDS (London, England)
2026

Kaposi sarcoma in lung transplant recipients with public health service increased-risk donors: A retrospective cohort study and review of the literature.

JHLT open
2026

Complete remission of HIV-associated glomerular disease with tacrolimus, followed by late-onset Kaposi sarcoma: A report of two cases.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2025

Gastrointestinal Kaposi Sarcoma: Histopathological Features and Diagnostic Challenges - Insights from a Single Center.

Sisli Etfal Hastanesi tip bulteni
2026

Analysis approaches to combine error-prone data with a subset of validated data: an application to a multinational study of Kaposi sarcoma and HIV.

American journal of epidemiology
2025

Iatrogenic Kaposi Sarcoma Revealed by Acral Nodules With Silent Pulmonary Involvement in Two Patients Treated for Autoimmune Blistering Diseases.

Cureus
2026

Ocular Surface Squamous Neoplasia Masqueraders.

Seminars in ophthalmology
2026

Cancer Risk and Mortality Following Kaposi Sarcoma Among People with HIV in the United States, 2000 to 2019.

Cancer causes &amp; control : CCC
2025

Kaposi Sarcoma: A Case of Mistaken Identity in an Immunocompetent Healthy Male.

European journal of case reports in internal medicine
2026

Unusual Presentation of Kaposi Sarcoma in a Virally Suppressed HIV Patient With High CD4 Counts.

International journal of dermatology
2026

Quality of life of patients with Kaposi Sarcoma: a cross-sectional study.

Italian journal of dermatology and venereology
2026

Atypical Presentation of Kaposi Sarcoma.

ACG case reports journal
2025

Diverse and Atypical Presentations of Acroangiodermatitis of Mali: Diagnostic Insights From Three Cases.

Cureus
2026

Targeting of Kaposi's sarcoma-associated herpesvirus by immunotoxins directed against the viral G protein-coupled receptor, ORF74.

Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie
2026

Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL.

PLoS pathogens
2026

Efficacy of Immune Checkpoint Inhibitors and Oncoviruses in Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research
2026

[Advances in cellular origin, clonality and clinicopathological research of Kaposi sarcoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology
2026

Spatial Profiling Shows That Lymphatic Endothelial Cells Form the Core of Kaposi Sarcoma (KS).

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
2026

Patient- and caregiver-reported barriers to chemotherapy in nine sub-Saharan African countries: A cross-sectional survey among population-based registries.

International journal of cancer
2026

Loop-Mediated Isothermal Amplification Enables Reliable Kaposi Sarcoma Diagnosis Across Time and Sites in East Africa.

Journal of medical virology
2025

Targeted Protein Degradation of the Latency-Associated Nuclear Antigen Evicts Kaposi Sarcoma-Associated Herpesvirus Episomes From Infected Cells In Vitro.

Journal of medical virology
2025

HHV-8-Associated Hemophagocytic Lymphohistiocytosis in a HIV-Negative and Nontransplant Man: A Case Report and Literature Review.

Case reports in infectious diseases
2025

Gastrointestinal Kaposi Sarcoma in Inflammatory Bowel Disease: Clinicopathological, Endoscopic, and Follow-Up Study of 6 Patients With Review of the Literature.

International journal of surgical pathology
2025

Posttransplant Malignancies in Adult Transplant Patients.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
2025

Real-world outcomes of immune checkpoint inhibitors in people with HIV and skin cancer: a multicentre study.

The oncologist
2026

Treatment With PD-1/PD-L1 Inhibitors for Kaposi Sarcoma:A Systematic Review and Meta-Analysis.

Journal of immunotherapy (Hagerstown, Md. : 1997)
2026

Evaluating the efficacy of treatment options for cutaneous HIV-related Kaposi sarcoma: A systematic review and meta-analysis.

Journal of the American Academy of Dermatology
2025

Rare Presentation of Kaposi Sarcoma Mimicking Madura Foot: A Case Report.

Clinical case reports
2026

Remission of recalcitrant pyoderma gangrenosum following chemotherapy for iatrogenic Kaposi sarcoma.

JAAD case reports
2026

Cancer prevalence and prognosis among individuals living with HIV and AIDS in Turkey: Multicenter BUHASDER study.

International journal of STD &amp; AIDS
2025

Powerful gene network enrichment analysis and its application to severe COVID-19 gene network.

Briefings in bioinformatics
2025

Spatial Transcriptomics of Patients With Kaposi Sarcoma Identifies Mechanisms of Immune Evasion.

Journal of medical virology
2025

An additional dermoscopic clue in basal cell carcinoma of the lower limb: the purpura-like pattern.

Clinical and experimental dermatology
2025

Serum Biomarkers in Advanced-Stage AIDS-Associated Kaposi Sarcoma in Resource Limited Settings.

Journal of acquired immune deficiency syndromes (1999)
2026

Artificial intelligence-powered signal analysis of loop-mediated isothermal amplification (LAMP) for the screening of Kaposi sarcoma at the point of care.

Sensors &amp; diagnostics
2026

Gastric Kaposi Sarcoma With Distinct "Lobster-Like" Endoscopic Lesions in a Human Immunodeficiency Virus-Positive Patient.

DEN open
2025

Human Herpes Virus-8 Oral Shedding Heterogeneity Is Due to Varying Rates of Reactivation from Latency and Immune Containment.

Viruses
2025

Laser Therapy for Cutaneous Kaposi Sarcoma: A Systematic Review and Meta-Analysis.

Cancers
2025

A Contemporary Multidimensional Insight into the Clinical and Pathological Presentation of Urological Conditions Associated with HIV: A Narrative Review.

Tropical medicine and infectious disease
2025

Data validation in multinational observational studies with error-prone data: applying an optimal validation sampling strategy in a study of Kaposi sarcoma and HIV.

American journal of epidemiology
2025

Humanized Mouse Models of Epstein Barr Virus Infection.

Current protocols
2025

Cost-effectiveness protocol for treating adult HIV-infected patients with Kaposi sarcoma in resource-limited settings: a phase III, randomized, open-label, non-inferiority study of paclitaxel and pegylated liposomal doxorubicin.

Cost effectiveness and resource allocation : C/E
2025

Kaposi sarcoma in a female patient with multiple sclerosis: a case report.

Journal of medical case reports
2026

Misdiagnosed: A Sigmoid Perforation Secondary to Visceral Kaposi Sarcoma.

Clinical colorectal cancer
2025

Virally encoded interleukin-6 (vIL-6) coordinates with human IL-6 to modulate cytokine expression during KSHV infection.

bioRxiv : the preprint server for biology
2025

Pleural Effusion in an HIV-Positive Patient: A Case Report and Review of Diagnostic Challenges.

Clinical case reports
2025

Unusual Presentation of Kaposi Sarcoma Mimicking Pyogenic Granuloma in an Immunocompetent Patient.

Acta medica portuguesa
2025

A Rare Constellation of Triple Cutaneous Malignancies With Sustained Therapeutic Response: Kaposi Sarcoma, Basal Cell Carcinoma, and Cutaneous Squamous Cell Carcinoma in a Single Patient.

Cureus
2025

Microbiome and metabolomics analyses of the effect of heat-sensitive moxibustion on allergic rhinitis in rats.

Frontiers in immunology
2025

Chylothorax and chylous ascites in AIDS-associated Kaposi sarcoma: a case report and literature review.

BMC infectious diseases
2026

Cytological Diagnosis of Primary Effusion Lymphoma in the Uncommon Clinical Setting of an HIV-Negative Patient With End-Stage Renal Disease: A Case Report and Literature Review.

Cytopathology : official journal of the British Society for Clinical Cytology
2025

Human immunodeficiency virus negative, immunocompetent primary effusion lymphoma with a complete response on R-miniCHOP.

CytoJournal
2025

Disseminated Kaposi sarcoma patients exhibit an expanded population of CD8+CD57+ T cells and an immunosenescence profile.

Frontiers in immunology
2025

Kaposi sarcoma incidence and mortality trends and disparities in the United States.

Infectious agents and cancer
2025

Plasmablastic Lymphoma With Intravascular Localization in a Kaposi Sarcoma Skin Lesion.

Journal of cutaneous pathology
2025

Recent Advances in the Histopathology, Molecular Biology, and Treatment of Kaposi Sarcoma: A Contemporary Review.

International journal of molecular sciences
2025

Risk Factors for the Development of Malignancies Post-Transplantation in Kidney Transplant Recipients.

Biomedicines
2025

Unilateral Acroangiodermatitis: From Histopathologic Confirmation to Treatment with PDL.

Dermatopathology (Basel, Switzerland)
2025

Diagnostic Challenges in HHV-8-Associated Multicentric Castleman Disease in a Patient with Prior Kaposi Sarcoma.

Dermatopathology (Basel, Switzerland)
2025

Simply the (B)EST: what the interventionalist needs to know about (bleomycin) electrosclerotherapy for vascular anomalies.

European radiology
2025

Eph receptor tyrosine kinases are functional entry receptors for murine gammaherpesvirus 68.

PLoS pathogens
2025

Cutaneous Squamous Cell Carcinoma Mimicking Kaposi Sarcoma in an HIV-Positive Patient: Diagnostic Challenges and Therapeutic Response to Liposomal Doxorubicin.

Cureus
2025

Integrase inhibitors and paclitaxel for Kaposi sarcoma: Clinical relevance of pharmacological interaction.

HIV medicine
2025

Oral Microbiome and Inferred Functions Predict Kaposi's Sarcoma Progression.

Journal of medical virology
2026

Clinicopathologic and radio-genomic insights into hepatic epithelioid hemangioma: An illustrated review.

Human pathology
2025

Atypical Manifestation of Disseminated Gastrointestinal Kaposi Sarcoma in a Newly Diagnosed HIV Patient: A Case Report.

Case reports in gastrointestinal medicine
2025

A Multimodal Radiation Approach to a Complex Case of Kaposi Sarcoma: Successful Treatment and Long-Term Follow-Up.

Cureus
2026

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases.

The FEBS journal
2025

Integrative functional genomics analysis of Kaposi sarcoma cohorts.

Scientific reports
2025

Infectious etiologies of conjunctival tumors.

Expert review of ophthalmology
2025

Nano-Luciferase complementation assay of human herpesvirus 8 chemo/cytokine-receptor interactions.

Scientific reports
2025

Relation between demographic status and clinical characteristics of Kaposi sarcoma: a single centre study.

Cutaneous and ocular toxicology
2025

Design, development, and evaluation of gene therapeutics specific to KSHV-associated diseases.

Molecular therapy. Oncology
2025

A Case of Kaposi Sarcoma Misdiagnosed for 2 years: A Case Report.

Case reports in medicine
2024

The Elevated Expression of ORF75, a Lytic KSHV Gene, in Kaposi Sarcoma Lesions is Driven by a GC-rich DNA cis Element in its Promoter Region.

bioRxiv : the preprint server for biology
2025

Immunotherapy of Oncovirus-Induced Cancers: A Review on the Development and Efficacy of Targeted Vaccines.

Vaccines
2025

Prevalence and Clinical Characteristics of Visceral Involvement in HIV-Associated Kaposi Sarcoma: A Three-Year Retrospective Cohort Study at a Tertiary Care Center in Mexico.

Microorganisms
2025

Castleman Disease and Kaposi Sarcoma: A Review of the Literature and a Case Series.

Journal of clinical medicine
2025

Collision Tumor of Angioimmunoblastic T-Cell Lymphoma and Kaposi Sarcoma in an HIV-Negative Elderly Woman: The First Reported Case in Asia.

Diagnostics (Basel, Switzerland)
2025

Cannabidiol in Skin Health: A Comprehensive Review of Topical Applications in Dermatology and Cosmetic Science.

Biomolecules
2026

Updates on Kaposi sarcoma.

Clinics in dermatology
2025

Classification of Kaposi Sarcoma Subtype in a Patient from Cape Verde.

Rhode Island medical journal (2013)
2025

Kaposi sarcoma: today, yesterday, and tomorrow.

AIDS (London, England)
2025

Preliminary assessment of drug repurposing against virus-associated primary effusion lymphoma.

Journal of microbiology &amp; biology education
2026

Diagnostic pitfalls: how availability and anchoring biases lead to errors in dermatology.

Diagnosis (Berlin, Germany)
2025

Venous Malformation-Like Kaposi Sarcoma: Revisiting a Known Variant.

The American Journal of dermatopathology
2025

Trends in the incidence of cancers related to HIV-AIDS in Harare, Zimbabwe 1990-2019.

Journal of the National Cancer Institute
2026

Solid masses arising in transplanted kidneys.

Abdominal radiology (New York)
2025

Radiotherapy of skin cancers.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
2025

Multicentric Castleman disease with splenic presentation: report of two rare cases with focus on histopathological features and review of the literature.

Virchows Archiv : an international journal of pathology
2025

Vesiculobullous eruption in an immunocompromised patient.

JAAD case reports
2025

The leader proteins of Theiler's virus and Boone cardiovirus use a combination of short linear motifs (SLiMs) to target RSK kinases to the nuclear pore complex.

Journal of virology
2026

Ethnicity and the epidemiology of skin cancer incidence: a national retrospective population-based study in England, 2013-20.

The British journal of dermatology
2025

Cytokine biomarkers and their relationship to symptoms and quality of life in people with HIV-associated Kaposi sarcoma.

HIV medicine
2025

Disseminated Kaposi Sarcoma With Ocular Involvement: An Unusual Multisystem Case Presentation.

Cureus
2025

HIV-associated gut dysbiosis drives oncogenesis through metabolic-immune crosstalk: mechanisms and therapeutic implications.

Frontiers in oncology
2025

Insights Into Kaposi Sarcoma-Associated Herpesvirus-Specific Humoral Responses.

Journal of medical virology
2025

Repurposing disulfiram: An innovative inhibitory approach against a broad spectrum of viruses.

Biochemical and biophysical research communications
2025

Outcome of systemic therapy in patients with advanced rare skin cancers: A retrospective multicenter DeCOG study of 209 patients.

European journal of cancer (Oxford, England : 1990)
2025

[Current status and challenges of AIDS-related malignant lymphoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology
2025

HIV-associated multicentric Castleman disease with Kaposi sarcoma: A case report with 120-week follow-up of HHV-8 after remission.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
2025

Demographics, Trends, and Cardiovascular Mortality in Kaposi Sarcoma Patients in the United States: An Analysis of Surveillance, Epidemiology, and End Results Database.

Health science reports
2025

Malignancies After Renal Transplantation: Frequency, Etiology, and Prognosis-A Single Center Experience.

Journal of clinical medicine
2025

Integrated Model of Cancer Control for Early Detection and Treatment in Adolescents and Young Adults Living With HIV: Protocol for a Cluster Randomized Controlled Trial.

JMIR research protocols
2025

Caspase cleavage of Kaposi sarcoma-associated herpesvirus proteins: a role for K5 in preventing caspase-mediated cell death during lytic replication.

Journal of virology
2025

Human Lymphatic Endothelial Cells Expressing NRASQ61R Model Characteristics of Kaposiform Lymphangiomatosis.

Pediatric blood &amp; cancer
2025

Incidence and risk of cancer emergence among patients post-kidney transplantation in Japan.

Clinical and experimental nephrology
2025

Global burden of cancer attributable to HIV: a worldwide incidence analysis.

The Lancet. Global health
2025

Isolated Lesion of Penile Kaposi Sarcoma in an HIV-Negative Male Patient.

Cureus
2025

A high-throughput zebrafish screen identifies novel candidate treatments for kaposiform lymphangiomatosis (KLA).

The Journal of experimental medicine
2025

Skin Deep and Lung Bound: A Tale of Disseminated Kaposi's Sarcoma.

The Journal of the Association of Physicians of India
2025

Oncogenic Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus on Cell Metabolism and Cell Transformation.

Journal of medical virology
2026

Clinical Predictors and Incidence of Kaposi Sarcoma Among Males With HIV in the Treat-All Era in the United States and Canada.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
2025

Epidemiology and Surveillance of Keratinocyte and Non-Keratinocyte Cancers in Paediatric Solid Organ Transplant Recipients: A Narrative Review.

The Australasian journal of dermatology
2025

RNA-interactome capture identifies SRSF3 as a key protein for herpesviral gene expression.

PNAS nexus
2025

Porcine Lymphotropic Herpesvirus (PLHV) Was Not Transmitted During Transplantation of Genetically Modified Pig Hearts into Baboons.

International journal of molecular sciences
2025

[Kaposi Sarcoma: Between the Skin and the World].

Acta medica portuguesa
2024

Molecular Mechanisms of KSHV Latency Establishment and Maintenance.

Current clinical microbiology reports
2025

Mediastinal lymphadenopathy: Causes, symptoms and factors predicting good yield of endoscopic ultrasound-guided biopsy.

World journal of clinical cases
2025

Spontaneous Regression of Oral Kaposi Sarcoma in an HIV Negative Male.

Head and neck pathology
2025

Novel Cereblon-Binding Immunomodulators Have Increased Potency Against Gammaherpesvirus- Associated Lymphomas In Vitro.

Journal of medical virology
2025

Characteristics and outcomes of Kaposi sarcoma herpesvirus-associated inflammatory cytokine syndrome.

Blood advances
2025

Comparison of clinical and prognostic characteristics of patients with classic and AIDS-related Kaposi sarcoma: A single-center experience.

Medicine
2025

Distinguishing Hemophagocytic Lymphohistiocytosis, Immune Reconstitution Inflammatory Syndrome, and HIV-Associated Immune Thrombocytopenic Purpura: A Challenging Case of Thrombocytopenia in AIDS.

Cureus
2025

Marked temporal decline in human herpesvirus-8 seroprevalence among people living with HIV in Istanbul, Türkiye.

Diagnostic microbiology and infectious disease
2025

HHV8-related diseases in solid organ transplantation: a case series and systematic literature review.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2025

Kaposi Sarcoma-Associated Herpesvirus and Kidney Disease.

Journal of medical virology
2025

Current State of AIDS-Related Malignant Lymphoma.

Viruses
2025

Oncoviruses in the Oral Cavity: Recent Advances in Understanding Viral Infections and Tumorigenesis.

International journal of molecular sciences
2025

Trends in Cancer Incidence and Associated Risk Factors in People Living with and Without HIV in Botswana: A Population-Based Cancer Registry Data Analysis from 1990 to 2021.

Cancers
2025

Survival After Diagnosis of HIV-Associated Kaposi Sarcoma Among Adults in East Africa in the "Treat-All" Era.

Journal of acquired immune deficiency syndromes (1999)
2025

The association of immunosuppression and HIV control with Kaposi sarcoma among patients on antiretroviral therapy.

AIDS (London, England)
2025

Trends in malignancies among patients having human immunodeficiency virus infection attending a tertiary care hospital in southwest India.

Medical journal, Armed Forces India
2025

Hemophagocytic lymphohistiocytosis syndrome (HLH) in HIV-associated Kaposi sarcoma patients: The first case series from a single center in Türkiye.

International journal of STD &amp; AIDS
2025

Disseminated Kaposi sarcoma presenting as an endophytic renal mass with concurrent primary effusion lymphoma: A case report.

IDCases
2025

Excellent Response Following Palliative Radiation for Locally Advanced Epidemic/AIDS-Associated Kaposi Sarcoma of the Lower Extremity: A Case Report.

Advances in radiation oncology
2025

A Case of Cutaneous Kaposi Sarcoma in a Patient Post-Heart Transplantation.

JACC. Case reports
2025

Phase I Trial to Evaluate the Safety of Intralesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma.

JCO oncology advances
2025

Off-Label Topical Application of Sirolimus (Rapamycin) for Dermatological Conditions.

Journal of cutaneous medicine and surgery
2025

HIV-Negative African American Man with Gastrointestinal Kaposi Sarcoma Associated with Adalimumab Treatment for Cardiac Sarcoidosis: A Case Report.

The American journal of case reports
2025

Non-Invasive Diagnostic Imaging in Kaposi Sarcoma Evaluation.

Diagnostics (Basel, Switzerland)
2025

The morphological spectrum of Castleman disease and related disorders: a report from the Lymphoma Workshop of the 22nd Meeting of the European Association of Hematopathology.

Virchows Archiv : an international journal of pathology
2025

Incidence of rare cancers during the COVID-19 pandemic: a US population-based study.

Journal of the National Cancer Institute
2025

Global research landscape of HIV and Kaposi's sarcoma: a visualized bibliometric analysis.

Frontiers in microbiology
2025

Kaposi Sarcoma Presenting as Retroperitoneal Lymphadenopathy: A Case Report.

Case reports in oncology
2025

KSHV vIL6 Inhibits Functional B Cell Maturation During De Novo Infection.

Journal of medical virology
2025

Kaposi Sarcoma-Associated Herpesvirus Sequencing in People Living With HIV in the Southern United States Reveals Subtype Diversity and Multiple Infections.

Journal of medical virology
2025

Viral associations with hematologic cancers.

Journal of the Formosan Medical Association = Taiwan yi zhi
2025

The Mouth Tells the Tale: Kaposi Sarcoma as the First Clue to Undiagnosed AIDS.

Cureus
Ver todos os 2.152 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Mogamulizumab-Associated Kaposi Sarcoma in 2 Patients With Primary Cutaneous T-Cell Lymphomas.
    JAMA dermatology· 2026· PMID 41671006mais citado
  2. Monoclonal neutralizing antibodies elicited by infection with Kaposi sarcoma-associated herpesvirus reveal critical sites of vulnerability on gH/gL.
    PLoS pathogens· 2026· PMID 41499715mais citado
  3. Correction: Systemic Expression of Kaposi Sarcoma Herpesvirus (KSHV) Vflip in Endothelial Cells Leads to a Profound Proinflammatory Phenotype and Myeloid Lineage Remodeling In Vivo.
    PLoS pathogens· 2026· PMID 41490181mais citado
  4. A viral Achilles' heel for EBV-positive lymphomas.
    Blood· 2026· PMID 41712297mais citado
  5. Obscure Small Bowel Bleeding From Visceral Kaposi Sarcoma Without Cutaneous Manifestations.
    The American journal of gastroenterology· 2026· PMID 40358465mais citado
  6. Non-canonical histone H3.3 and its chaperones HIRA and DAXX participate in the regulation of KSHV latency.
    bioRxiv· 2026· PMID 41993451recente
  7. Kaposi Sarcoma Associated with Pemphigus Vulgaris in the Setting of Immunosuppressive Therapy: Case Report and Review of Literature.
    Case Rep Dermatol· 2026· PMID 41983146recente
  8. Disseminated Kaposi Sarcoma: Unveiling the undiagnosed HIV.
    QJM· 2026· PMID 41965074recente
  9. Kaposi sarcoma in solid organ transplant recipients: updates in epidemiology, diagnosis, treatment and prevention.
    Front Immunol· 2026· PMID 41953036recente
  10. Skin conditions in persons living with HIV during hospital admission in the UK.
    Skin Health Dis· 2026· PMID 41923957recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:33276(Orphanet)
  2. MONDO:0005055(MONDO)
  3. GARD:6814(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q725345(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Sarcoma de Kaposi
Compêndio · Raras BR

Sarcoma de Kaposi

ORPHA:33276 · MONDO:0005055
Prevalência
1-9 / 100 000
Herança
Not applicable
CID-10
C46.0 · Sarcoma de Kaposi da pele
CID-11
Ensaios
25 ativos
Início
Adult
Prevalência
0.0 (Europe)
MedGen
UMLS
C0036220
Repurposing
1 candidato
vinblastinemicrotubule inhibitor|tubulin polymerization inhibitor
EuropePMC
Wikidata
Wikipedia
Papers 10a
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