Monitoring the Progression of Pre-Ataxic Gait in SCA2 with Inertial Sensors Over Four Years.

Short-term lesion-level impact of extensive LDL-C reduction with statins and PCSK9 inhibitors: a pre-specified subgroup analysis of the randomized FITTER trial.

Joint TOS/OMA/OAC expert guidance statement on the pharmacological management of United States adults with overweight or obesity using the GRADE approach.

Differences in Prevalence and Severity of Liver Disease Between Lateral Tunnel and Extracardiac Conduit Fontan.

Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants.

Variability in BIA-Derived Muscle Mass Estimates: Device Choice Impacts Diagnostic Classification.

Holistic Value Assessment of Tirbanibulin for Actinic Keratosis: European Multi-Criteria Decision Analysis.

Metabolically reprogrammed eosinophils impair T cell immunity and cause chronic skin infection.

VIKTORIA-1 Trial of Gedatolisib Plus Fulvestrant With or Without Palbociclib in Hormone Receptor-Positive/HER2-/PIK3CA Wild-Type Advanced Breast Cancer.

MYH9 Variant p.(Arg424Gly) Alters Nonmuscle Myosin IIA Contraction, Causing Atypical MYH9-related Disease.

Resistance to anti-PD-1 immunotherapy for stage III and IV melanoma: a global chart review study.

Development of Radiomics Models to Predict Progression-Free Survival and Early Polymetastatic Progression in Patients With Lung Oligometastases Treated on the Single-Arm Phase II Stereotactic Ablative Radiotherapy-5 Trial.

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review.

Title: Symptomatic hypocalcemia is uncommon in patients with liver disease undergoing low-volume plasma exchange by centrifugal technique.

Beyond Survival: Factors Driving Textbook Outcome After Simultaneous Pancreas-Kidney Transplantation-A Retrospective Analysis.

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol-related behaviour and affective state in mice.

Real-world data on anti-PD-1 plus lenvatinib as a treatment option in pretreated advanced melanoma patients - a retrospective DeCOG study.

Wild-type cutoff values for standard broth microdilution antimicrobial susceptibility testing of Yersinia ruckeri isolates.

Identification of serum protein biomarkers in individuals with Niemann-Pick disease, type C1.

Long-term adverse multi-system health outcomes of gestational diabetes mellitus: an analysis of real-world cohort data.

Epidemiology of adult T-cell leukemia/lymphoma (ATL) in people living with HTLV-1: A 30-year study in Peru.

Effect of semaglutide on COVID-19 and other infections: an analysis from the FLOW randomized clinical trial.

Female genital mutilation/cutting experiences and attitudes among women from countries with high prevalence of FGM/C living in the United States: findings from the women's health needs study.

Machine learning to optimize the diagnostic performance of natriuretic peptides for acute heart failure across age groups.

Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron.

Kidney and Survival Outcomes with Semaglutide by CKD Severity in the FLOW Trial.

Type I IFN-dependent FcγRIV signaling in murine monocytes promotes lethal anaphylaxis during viral infections.

Coxiella burnetii infects osteoclasts and alters their differentiation and function in a type IV secretion system-dependent manner.

Acoramidis in transthyretin amyloid cardiomyopathy: expanding evidence from ATTRibute-CM.

Immunogenicity, reactogenicity, and safety to assess booster vaccinations with BNT162b2 or double-dose mRNA-1273 in adults ≥75 years (EU-COVAT-1-AGED)-final report.

An oncogenic KRAS-driven secretome involving TNFα promotes niche preparation prior to pancreatic cancer onset.

Daratumumab in systemic lupus erythematosus: a single-arm phase 2 trial.

Oral Semaglutide and Heart Failure Outcomes in Persons With Type 2 Diabetes: A Secondary Analysis of the SOUL Randomized Clinical Trial.

Efficacy and Safety of Oral Treprostinil in Patients with Pulmonary Arterial Hypertension on Background Monotherapy or Dual Therapy.

Role of comorbidities and medication on immunotherapy efficacy in cSCC: A DeCOG multicentre analysis.

Safety of a remote disease management program to improve sodium-glucose cotransporter-2 inhibitors and glucagon-like peptide-1 receptor agonists prescribing in type 2 diabetes with elevated cardiovascular or kidney risk.

Evidence supporting the role of longitudinal NT-proBNP assessment for risk stratification in adults with congenital heart disease.

In vitro activity of gepotidacin against a challenging panel of multidrug-resistant Neisseria gonorrhoeae isolates.

Free-breathing phase-resolved functional lung (PREFUL) low-field magnetic resonance imaging (LF-MRI) of pulmonary dysfunction after surviving childhood cancer.

Beyond the surface: soluble SIGLEC-1 as a clinically applicable type I IFN biomarker.

Tetraspanin-based immunocapture for high-depth proteomic profiling of extracellular vesicles from cerebrospinal fluid for biomarker discovery.

Olezarsen reduces all-cause health services utilization and improves the treatment experience of patients with familial chylomicronemia syndrome.

Characterization of liver disease in a cohort of individuals with Niemann-Pick Disease, Type C1.

Genetic tumor syndromes in female cancer: insights into inherited cancer predisposition and clinical implications.

Global glucagon-like peptide-2 receptor activation linked to increased obesity risk in the UK Biobank.

Treatment of type 2 diabetes among medicare beneficiaries with and without alzheimer's disease: A retrospective cohort study.

Decoding gray matter, large-scale analysis of brain cell morphometry to inform microstructural modeling of diffusion MR signals.

2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.

Risk of Hyperkalemia With Empagliflozin, Finerenone, or Both: Secondary Analysis of the CONFIDENCE Randomized Trial.

Targeting treatment-resistant social anxiety with sitagliptin: Effects on social fear and comorbid depressive-like behavior in a preclinical model.

Spontaneous activity in pain patient stem cell-derived sensory neurons arises from one functional subclass.

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus.

Efficacy and safety of microbiota-targeted therapeutics in autoimmune and inflammatory rheumatic diseases: protocol for a systematic review and meta-analysis of randomised controlled trials.

Experimental Approaches for Biochemical Analysis of Glial Fibrillary Acidic Protein and Its Disease-associated Variants.

Tolerance to ferroptosis facilitates lipid metabolism and pathogenic type 2 immunity in allergic airway inflammation.

Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial.

Skin-analogue primary poroid neoplasms of the head and neck with YAP1/WWTR1::MAML2/NUTM1 fusions: clinicopathologic and genetic spectrum of a novel tumor family delineated in a series of 10 cases.

Genotype-phenotype correlations of GFAP variants in type I Alexander disease subtypes.

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines.

Gene-environment interplay explaining individual variation in BMI outcomes: a systematic review and meta-analysis of studies using polygenic indices.

Neurological manifestations and clinical outcomes in pediatric Alexander disease: single-center cohort and identification of novel GFAP variants.

Ethnic differences in risk of renal disease progression amongst young-onset type 2 diabetes in New Zealand.

The intermediate filament protein GFAP regulates mitochondrial fission in astrocytes.

Progression of Gait Ataxia in Spinocerebellar Ataxia Type 2: Clinical Utility of Digitally Measured Gait Metrics.

Phylogenomic analysis and genetic mechanisms of antifungal resistance in clinical isolates of Candida glabrata (Nakaseomyces glabratus) from across Canada, 2013-2020.

Outcomes following matched sibling donor transplantation for severe combined immunodeficiency: a report from the PIDTC.

LIVER-R study protocol: a global real-world study of durvalumab-based regimens in patients with hepatobiliary cancers.

BACE1 regulates sleep-wake cycle through both enzymatic and non-enzymatic actions.

Genetic variants in ESRRG are associated with a dominant non-progressive congenital movement disorder with ataxia.

ASTRA: a comprehensive resource of stress-induced transcriptional activity in human cell lines.

Utility of 24(S)-hydroxycholesterol as a proximal biomarker to monitor long-term intrathecal adrabetadex therapy in individuals with Niemann-Pick disease, type C1.

End-of-life care utilization of older adults with heart failure and/or COPD: the role of family availability.

EBM BLS: Semaglutide Reduces Kidney Disease Progression in Patients with Type 2 Diabetes and Chronic Kidney Disease.

Lung basement membranes are compositionally and structurally altered following resolution of influenza infection.

Comparative in vitro susceptibility of clinical Leishmania isolates to miltefosine and oleylphosphocholine.

Advancing arabinose-based bioproduction in Yarrowia lipolytica by integrating metabolic engineering and adaptive laboratory evolution.

Coramitug, a Humanized Monoclonal Antibody for the Treatment of Transthyretin Amyloid Cardiomyopathy: A Phase 2, Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial.

Efficacy of Acoramidis in Wild-Type and Variant Transthyretin Amyloid Cardiomyopathy: Results From ATTRibute-CM and Its Open-Label Extension.

Baseline Kidney Function, Albuminuria, and Urine Albumin-Creatinine Ratio Reduction with Finerenone, Empagliflozin, or Both: Post Hoc Analyses of CONFIDENCE Trial.

Short- and mid-term effects of empagliflozin on sodium balance and fluid regulation in chronic heart failure.

Regional brain morphology and current antidepressant use: findings from 32 international cohorts from the ENIGMA major depressive disorder working group.

Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q-Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study.

Chronic optogenetic activation of hippocampal CA1 neurons triggers Alzheimer's disease-like proteomic remodeling.

R405W Desmin Knock-In Mice Highlight Alterations of Mitochondria, Protein Quality Control and Myofibrils in Myofibrillar Myopathy.

First genome-wide association study reveals immune-mediated aetiopathology in idiopathic achalasia.

Dietary ω-3 polyunsaturated fatty acids (PUFAs) reduce cholesterol-driven non-small cell lung cancer (NSCLC) progression in mouse models of disease.

Fenestrating Adenocarcinoma: A Novel Salivary Gland Cancer With EWSR1::BEND2 Fusion and Predilection for the Pharynx.

Identification of a novel PDE4 inhibitor inspired by leoligin-derived lignans.

A phase Ib/II trial of neoadjuvant neratinib added to standard therapy in patients with HER2-positive or HR-positive/HER2-negative inflammatory breast cancer (including stage III and IV disease).

The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration.

Entheseal tissue signature in response to IL-17A inhibition in psoriatic arthritis: results from the EBIO entheseal biopsy study.

Weak influence of light and time of day on transcriptional response to SAV3 infection in Atlantic salmon (Salmo salar) smolts.

Soluble BDCA-2 as a potential biomarker for rheumatoid arthritis and its role in enhancing IFN-α production through nucleic acid binding.

Knowledge, attitude, and quality of life among newly diagnosed type 2 diabetic patients attending diabetic clinics at Bugando Medical Centre, Mwanza, Tanzania.

Pancreatic transdifferentiation of NOD mouse livers prevented development of hyperglycemia.

Elevated Interleukin-8 in Spinocerebellar Ataxia Type 2: A Distinct Peripheral Immune Signature Unrelated To Disease Severity.

Basophils in Skin-Mediated Sensitization Drive Subsequent Lung Inflammation in Airway-Challenged Mice.

Novel COL4A1 missense variant in a case of juvenile stroke.

Which Psycho-Oncological Interventions Are Applied in an Acute Care Hospital in Germany?-An Exploratory Retrospective Cross-Sectional Single Center Study.

BEAM/ATG or cyclophosphamide/ATG as conditioning regimen in autologous haemopoietic stem cell transplantation for multiple sclerosis: a retrospective analysis of the EBMT autoimmune diseases working party.

JUNB and JUND in Urological Cancers: A Literature Review.

Association of BMI and Cognitive Performance in the Diabetes Prevention Program Outcomes Study.

Differential TGF-β2 expression in the anterior and posterior eye segments in mice with early streptozotocin-induced diabetes.

CD163/CD63+ Monocyte-Derived DC Profiled in Tissue by Multi-Antigen Analysis (MAA) Discriminate Chronic Eczema and Psoriasis.

Individual lipid alterations at the origin of neuronal Ceramide Synthase defects.

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice.

Impact of Baseline GLP-1 Receptor Agonist Use on Albuminuria Reduction and Safety With Simultaneous Initiation of Finerenone and Empagliflozin in Type 2 Diabetes and Chronic Kidney Disease (CONFIDENCE Trial).

Quantification of Exercise-Induced Sarcomeric Damage in R349P Desmin Knock-In Mice: A New Approach in Myofibrillar Myopathy Research.

Molecular Characterization of the GALC Mutation Thr112Ala Causing Krabbe Disease.

Phenotypic intrafamilial variability of 5q-associated spinal muscular atrophy: A systematic multicentre sibling study.

Inferior Vena Cava Ultrasound to Guide Decongestion in Acute Decompensated Heart Failure: A Randomized Controlled Trial.

Indications for haematopoietic cell transplantation and CAR-T for haematological diseases, solid tumours and immune disorders: 2025 EBMT practice recommendations.

Impaired Pulmonary Vascular Reserve in Adults with Repaired Coarctation of Aorta: Prevalence, Correlates, and Association with Disease Severity.

Breaking primary checkpoint inhibitor resistance with intermittent alkylating chemotherapy in patients with metastatic melanoma: results of a multicentre phase II trial.

Evaluating diabetes self-management education and support services delivered alone and in combination with produce packages at a Texas Food Bank.

Impact of myotomy length on per-oral endoscopic myotomy (POEM) outcomes for achalasia: a meta-analysis of randomized trials.

Context dependent role of miR-486 promoting neuroregeneration of primary sensory neurons downstream of interleukin-6 signal transducer.

Micrometastasis and Isolated Tumor Cells in Oral Squamous Cell Carcinoma: Refining Nodal Staging with Emerging Technologies.

Simultaneous initiation of finerenone and empagliflozin across the spectrum of kidney risk in the CONFIDENCE trial.

Extracorporeal photopheresis reduces the T cell stimulatory capacity of human primary blood conventional dendritic cells type 1.

Association between polygenic risk and survival in breast cancer patients.

Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma.

Early treatment with vildagliptin and linagliptin reduces social fear and prevents the onset of comorbid depression in a mouse model of social anxiety disorder.

Self-reported Clinical Outcomes and Quality of Life in Agammaglobulinemia: the Importance of an Early Diagnosis.

Roles of the lipopolysaccharide biosynthesis-related gene HP0858 in the fitness of Helicobacter pylori and its virulence in Galleria mellonella.

Interstitial Lung Disease Associated with Autoimmune Rheumatic Diseases: An Experience from Türkiye.

Seizure Activity and Hypoxia Differentially Regulate Endogenous Neurotrophic Activin A and Neuroglobin Expression in the Immature Mouse Brain.

Racial Differences in Length of Stay After Atrial Fibrillation Ablation.

Brain Endothelial Soluble ST2 Production and Cerebral Edema in a Rat Model of Ischemic Stroke.

Saccharomyces cerevisiae as a Model for Reprogramming of Eukaryotic Cells: Implications for the Study of the Relationship Between Metabolism and Inflammation in Chronic Disease.

Serum neurofilament light protein as a biomarker in Niemann-Pick disease, type C1.

Best Oculomotor Endpoints for Clinical Trials in Hereditary Ataxias: A Systematic Review and Consensus by the Ataxia Global Initiative Working Group on Digital‑Motor Biomarkers.

A scoping review protocol: Neuropsychological development in pediatric ophthalmology patients with social determinants of health analysis.

Malignant triton tumor of the common bile duct.

Prognostic impact of the choice of chemotherapy after first-line CDK4/6 inhibitor therapy in patients with metastatic hormone receptor-positive, HER2-negative breast cancer.

Epigenetic liquid biopsies reveal endothelial turnover and erythropoiesis in asymptomatic COVID-19.

Changes in prescribing patterns and access to immune checkpoint inhibitors in german lung cancer patients - a claims data analysis.

Mutations in GFAP Alter Early Lineage Commitment of Organoids.

Functional Autoantibodies Targeting G-Protein-Coupled Receptors and Their Clinical Phenotype in Patients with Long-COVID.

Prevalence and survival outcomes of adult T-cell leukemia/lymphoma in Latin America: A multicenter cohort study and recommendations to improve diagnosis and outcomes.

Co-occurrence of multiple pathologies in a case of frontotemporal dementia with TBK1 mutation: first in vivo detection of alpha-synuclein and tau co-pathology.

Differential molecular signatures in response to CD19-CAR T cell therapy compared with conventional pharmacotherapy in systemic lupus erythematosus.

CYP1B1 knockout enhanced IFN-γ production is required but not sufficient for protection of cigarette smoke-exposed mice against lethal influenza virus infection.

Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosis.

Longitudinal measurements of NO-mediated vasodilation and physical activity over 1 yr following endometriosis excision surgery: a passive experiment.

Impaired Autophagic Flux in Skeletal Muscle of Plectin-Related Epidermolysis Bullosa Simplex With Muscular Dystrophy.

Comparative Prognosis by Stress ECG and Stress Imaging: Results From the ISCHEMIA Trial.

Gene therapy enhances deoxyribonuclease I treatment in antimyeloperoxidase glomerulonephritis.

Biofabrication of a Filtration Barrier by Integrating Electrospun Membranes and Flow in a Glomerular Co-Culture.

Loss of NR2F6 Protects from Salmonella Typhimurium Infection.

Humoral vaccine responses following Chimeric Antigen Receptor T-cell therapy for hematological malignancies.

Mast cells infiltrates are common in eosinophilic esophagitis and still elevated in histological remission: A digital evaluation in children.

Relationship between hydroxychloroquine blood levels and lupus activity through the lens of the type 1 and type 2 lupus model: a cross-sectional study.

Ogerin Inhibits Development of Post-Operative Abdominal Adhesions in a Murine Model.

US Public Health Gains from Improved Treatment of Hypercholesterolemia: A Simulation Study of NHANES Adults Treated to Guideline-Directed Therapy.

Small U-Net for Fast and Reliable Segmentation in Imaging Flow Cytometry.

Infrapopliteal bypass surgery in the endovascular era.

Letermovir prophylaxis for cytomegalovirus infection in hematopoietic transplantation with post-transplant cyclophosphamide.

Beyond the Scale: The Hidden Burden of Underweight and Cachexia in Adults with Congenital Heart Defects and Heart Failure-Results from the Pathfinder CHD-Registry.

The SGLT2 Inhibitor Empagliflozin Mitigates the Harmful Effects of Methylglyoxal Exposure on Ovalbumin-Induced Mouse Airway Inflammation.

Crosstalk between oxidative stress, mitochondrial dysfunction, chromosome instability, and the activation of the cGAS-STING/IFN pathway in systemic sclerosis.

Consensus Guideline for the Management of Patients with Appendiceal Tumors, Part 2: Appendiceal Tumors with Peritoneal Involvement.

The Epidemiology of Cervical Cancer in Germany: A Registry-Based Analysis of Incidence, Survival, and Tumor Characteristics (2003–2021).

Convergent Validity of the Fine Motor, Speech, and Cognitive Domains of the 5-Domain Niemann-Pick Disease Type C Clinical Severity Scale.

What Is the Cumulative Incidence of Femoral Stem Revision and Stem Complication in Cemented and Uncemented Hip Arthroplasty for Proximal Femoral Metastatic Bone Disease?

Ultra-fast MRI for dementia diagnosis and treatment eligibility: A prospective study.

Clinical and microbiological characteristics of pediatric patients hospitalized for pneumococcal pneumonia before and after the introduction of pneumococcal conjugate vaccines.

Prognostic Significance of Macrophage Phenotypes in Peri-Tumoral Normal Tissue of Early-Stage Breast Cancer.

Sitagliptin as a therapeutic approach for social anxiety disorder: the role of DPP4 and NPY in modulating social fear and comorbid depressive-like behavior in mice.

COL4A5-p.Gly624Asp is the Predominant Variant in Europe Associated With a Mild Alport Syndrome Phenotype.

Chemical chaperone 4-phenylbutyrate treatment alleviates the kidney phenotype in a mouse model of Alport syndrome with a pathogenic variant in Col4a3.

High-throughput differentiation of human blood vessel organoids reveals overlapping and distinct functions of the cerebral cavernous malformation proteins.

Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes.

Single cell profiling of human airway identifies tuft-ionocyte progenitor cells displaying cytokine-dependent differentiation bias in vitro.

Successful Anesthetic Management for Laparoscopic Gynecological Surgery in Adult-Onset Alexander's Disease: A Case Report.

The emerging role of GlycoRNAs in immune regulation and recognition.

The Mini-COMET Clinical Trial: Safety and Efficacy of Avalglucosidase Alfa after 97 Weeks of Treatment in Children with Infantile-Onset Pompe Disease Previously Treated with Alglucosidase Alfa.

Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in primary care.

Efficacy and safety of rigosertib in patients with recessive dystrophic epidermolysis bullosa-associated advanced/metastatic cutaneous squamous cell carcinoma.

Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.

Impact of surgical case load on recurrence rates in pilonidal sinus disease: a cross-study data synthesis.

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types.

Extracorporeal Shock Wave Therapy for Chronic Adhesive Capsulitis in Type 2 Diabetics: A Systematic Review With Meta-Analysis.

Dominant variants in major spliceosome U4 and U5 small nuclear RNA genes cause neurodevelopmental disorders through splicing disruption.

Targeting interferon responses in juvenile dermatomyositis: Siglec-1 as an in vitro biomarker for JAK inhibitor efficacy.

HPDL Variant Type Correlates With Clinical Disease Onset and Severity.

Changes in Chronic Graft-versus-Host Disease Treatment Over Time: A 15-Years Survey Within Allogeneic Hematopoietic Stem Cell Transplant Centers in Germany, Austria, and Switzerland.

Glands of Moll: history, current knowledge and their role in ocular surface homeostasis and disease.

Multi-Epitope DC Vaccines with Melanoma Antigens for Immunotherapy of Melanoma.

Inflammatory Skin Diseases: The Importance of Immunological Signatures.

Bilateral vestibulopathy in Alexander disease type II- a case report.

Case Finding for Celiac Disease With a Point-of-Care Test.

Bridging acute and chronic stress effects on inflammation: protocol for a mixed-methods intensive longitudinal study.

CD55 upregulation in T cells of COVID-19 patients suppresses type-I interferon responses.

Cell type mapping of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsy using single-nucleus multiomics.

Polymorphic tandem repeats influence cell type-specific gene expression across the human immune landscape.

Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations.