Tyrosine Hydroxylase Deficiency Impairs TH Axonal Transport, Brain Function, and Neuronal Plasticity.

Synchronous activation of striatal cholinergic interneurons induces local serotonin release.

Fear extinction induces maladaptive generalization via noradrenergic and GABAergic systems.

Hypocretin receptor 1 blockade early in abstinence reduces future demand for cocaine.

NMDA receptor antagonism requires serotonin and noradrenaline to induce antidepressant-like effects in a treatment-resistant depression rat model.

Exploring the neurofunctional potential of saffron bioactives: from mood-related behavioral modulation to brain access of safranal.

Chronic Histamine Exposure Promotes Melanogenesis via ORAI1-STIM1-Mediated Calcium Signaling Remodeling.

Membrane Dysfunction as a Central Mechanism in LRRK2-Associated Parkinson's Disease: Comparative Analysis of G2019S and I1371V Variants.

Alterations in the jejunal 5-hydroxytryptamine synthesis and turnover in septic mice induced by cecal ligation and puncture.

Novel positive allosteric modulators of alpha 5 subunit-containing GABAA receptors (α5-GABAARs) reverse the hyperdopaminergic state in a neurodevelopmental model of schizophrenia.

Multiomics analysis of polyamine metabolism in colorectal cancer, highlighting the key role of extracellular putrescine in impairing CXCR6+CD8+ T cell anti-tumor activity.

Alpha-methyl-para-tyrosine and amphetamine ameliorate hyperactivity in a novel mouse model of dopamine transporter deficiency syndrome.

The impact of predator stress on electroshock seizure threshold: insights into GABAergic, glutamatergic, and serotonergic pathways in mice.

Rhubarb enhances gastrointestinal motility via calcium-mediated intestinal acetylcholine release: a network pharmacology study.

Serotonin, Kynurenine, and Indole Pathways of Tryptophan Metabolism in Humans in Health and Disease.

Synaptogyrin-3 plays a critical role in addiction-related dopamine dysfunction and behavioral maladaptations.

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson's neurons.

An emerging role for synaptic Zn2+ in substance use disorders.

Altered serotonergic system and mood behaviors in a cuprizone-induced model of demyelination.

Multicolor Quantum Dot Tracking Uncovers Phenotypic Rescue of DAT A559V Aberrant Diffusion Upon D2R Antagonism.

Are glutathionylated aldehyde reductases the missing piece of the "catecholaldehyde hypothesis" in Parkinson's disease? A medical hypothesis concerning the detoxification of 4-hydroxynonenal (HNE) and 3,4-dihydroxyphenylacetaldehyde (DOPAL).

Prenatal Stress and Prenatal Alcohol Alter the Adult Dopamine System and Alcohol Consumption: Dopamine Drives Drinking Behavior in a Prospective 20-Year Longitudinal Experiment with Rhesus Macaques.

Neuropeptide S Protects Dopaminergic Neurons in a Paraquat-Induced Parkinson's Model Using SH-SY5Y Cells.

Pharmacological activity of a new ligand binding at the histamine site of the NMDA receptor in rodents.

α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction.

Mouse model of atypical DAT deficiency syndrome uncovers dopamine dysfunction associated with parkinsonism and ADHD.

"Summertime sadness": Striatal dopamine binding decreases during warmer seasons in patients with severe depression.

Neurochemical and behavioral evidence of high abuse liability of 3F-NEB, a novel synthetic cathinone.

VGLUT2 in Parkinson's disease: an emerging therapeutic target.

Intrinsic connectivity patterns of striatal subfields predict individual dimensions of psychopathology and are associated with cholinergic and serotonergic neurotransmission in schizophrenia.

Synaptic effects of interleukin-6 on human iPSC-derived dopaminergic neurons.

ATP13A2-Mediated Spermine Export Modulates Lipid Catabolism in the Endolysosomal System of SH-SY5Y Cells.

Disruption of the Placenta-Brain Axis in Transgenic Mice Lacking Serotonin Transporter (SERT) in Trophoblast Cells.

Elevated serotonin receptor 2A signaling restores learning and memory in a Fragile X syndrome model.

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment.

Margatoxin Peptide: Preparation and the Potential Use for Biological Applications in Cancer and Neurological Disorders.

Effects of Kamikihito on the Noradrenergic System and Its Pharmacokinetic Profile.

LPS-Induced Neuroinflammation Increases Serotonin-Evoked Activity of Trigeminal Afferents and Aggravates Mechanical Allodynia and Photophobic Behavior in Rat Migraine Model.

Dopamine and serotonin neurotransmissions exert complementary control over primate approach and avoidance.

Deciphering Ibogaine's Matrix Pharmacology: Multiple Transporter Modulation at Serotonin Synapses.

Gestational physical exercise prevents early-life behavioral impairments in the offspring of a rat model of attention deficit hyperactivity disorder.

Teneurin-4 knockdown disrupts dopamine dynamics and attenuates methamphetamine-induced behaviors.

TNF-α signaling mediates the dopaminergic effects of methamphetamine by stimulating dopamine transporters and L-type Ca2+ channels.

Structural basis for pharmacotherapeutic action of triple reuptake inhibitors.

Time-specific perturbation of the serotonergic system differentially modulates the transcriptional landscape of hippocampal subregions in female rats.

A co-culture model of dopaminergic and glutamatergic neurons derived from patients with idiopathic schizophrenia reveals a hypodopaminergic phenotype.

Degenerative pathologies on cortical biopsy, dopaminergic depletion, and shunt efficacy in iNPH.

Dynamic changes in chloride homeostasis coordinate midbrain inhibitory network activity during reward learning.

Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity.

Neurotropic Effects In Vivo of New Tryptamino-Triazines Compared to GABA Effectors.

Microbial dysbiosis alters serotonin signaling in a postinflammatory murine model of visceral pain.

Oreonudines A-H, Benzylisoquinoline-Derived Alkaloids with Diverse Skeletons from Oreomecon nudicaulis and Their Antidepressant Activities.

[Research progress of neurotransmitters in lung injury after traumatic brain injury].

L. johnsonii alleviates methamphetamine craving via the metabolism of tyrosine.

Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum.

Genetic Predisposition and Genetic Resilience Factors in Stress-Related Disorders During the Developmental Age: A Narrative Review.

Spermidine Prevents Polarity Loss of Absorptive Enterocytes in Jejunum of Lipopolysaccharide-Challenged Mice via 4D-DIA Proteomics Analysis.

Therapeutic potential of KATP channels in the attenuation of Parkinson's disease pathogenesis and progression - A review.

Serotonergic Neuromodulation of Natural Products Isoreserpine and Isoreserpiline in Adult Zebrafish: An in Silico and In Vivo Investigation.

Altered Dopamine Signaling in Extinction-Deficient Mice.

Noradrenergic α2 Receptor Modulates Cav2.2-Mediated Nociception in Parkinson's Disease Through Spinal Neuro-glial Network.

Structural basis of vilazodone dual binding mode to the serotonin transporter.

Targeting Serotonin Pathways for Astronaut Safety and Performance.

Association of dopamine depletion and cholinergic basal forebrain atrophy with brain metabolism and cognition in Parkinson's disease.

Comparative Analysis of Cholinergic Machinery in Carcinomas: Discovery of Membrane-Tethered ChAT as Evidence for Surface-Based ACh Synthesis in Neuroblastoma Cells.

Cooperative Ionic Coordination Governs Dopamine Transporter Dynamics and Substrate Translocation: Mechanistic Insights from Molecular Simulations.

Unrevealing the role of hypothalamic corticotropin-releasing hormone neurons in blood pressure regulation in hypertension.

Sensitive and enzyme-free detection of epinephrine based on porous platinum nanoflowers assembling into multiwalled carbon nanotubes-graphene quantum dots hybrid modified electrode.

Transcriptomics and Proteomics Identify Serotonin Transporter as a Promising Therapeutic Target for Essential Tremor.

Impaired cardiac non-neuronal acetylcholine synthesis triggers mitochondrial dysfunction with the loss of nicotinic receptor-mediated calcium handling, causing the failing heart.

Molecular basis of vesicular monoamine transport and neurological drug interactions.

Transient Suppression of Dopamine Transporter Palmitoylation by Methamphetamine: Implications for Transport Regulation.

Age-Dependent Redistribution of the Life-Important Enzyme in the Retina: Adult Müller Glial Cells' Endfeet Lack Spermine Synthase Expression.

Disentangling the Effects of Suicide Attempts and Psychiatric Diagnosis Based on a Genotype-Informed Dynamic Model of the Serotonin Presynapse.

Addressing the serotonin hypothesis of depression through analyses of genetics, methylation and metabolite variations in glioma patients.

[Neuroprotective effects of idebenone combined with borneol via the dopamine signaling pathway in a transgenic zebrafish model of Parkinson's disease].

Altered Dopamine Metabolism and Response to Treatment with Levodopa/Carbidopa in MCT8 Deficiency.

Relationship between striatal dopaminergic depletion and cognitive milestone in Parkinson's disease: A comprehensive analysis of striatal subregions, laterality, and nonlinear relationships.

Blockade of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels reduces alcohol-induced dopamine release and reward in rats.

Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential.

Epigenetic alterations of serotonergic but not dopaminergic signalling in compulsive sexual behaviour disorder.

Dopamine disruption and autism phenotypes in slc6a3-/- zebrafish: Behavioural and molecular insights.

Au@MOF-199 functionalized graphene oxide nanocomposite for simultaneous electrochemical detection of dopamine and uric acid.

The Central Cholinergic Synapse: A Primer.

The Human Alpha3 Beta2 Neuronal Nicotinic Acetylcholine Receptor Can Form Two Distinguishable Subtypes.

Serotonergic and Cholinergic Imbalance in the Offspring of Rats Exposed to Bisphenol A and Bisphenol S During Pregnancy and Lactation: Short- and Long-Term Effects.

[Mechanism of Xiangshao Granules in alleviating anxiety and depression in mice based on integrated metabolomics and gut microbiota].

Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity.

Novel Ways of Targeting the Dopamine Transporter.

Monoamine Transporters in Drugs of Abuse: Insights from Fast Scan Cyclic Voltammetry.

Causal Mechanisms of Monoamine Transporter Phosphorylation.

Regulation of Dopamine Transporter Surface Expression.

Cortical astrocyte histamine-1-receptors regulate intracellular calcium and extracellular adenosine dynamics across sleep and wake.

Immunometabolic reprogramming of macrophages by gut microbiota-derived cadaverine controls colon inflammation.

Modulation of Autism-Associated Serotonin Transporters by Palmitoylation: Insights into the Molecular Pathogenesis and Targeted Therapies for Autism Spectrum Disorder.

Regular versus Irregular Exercise Differentially Modulates Hippocampal-Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation.

[Effect of auricular point electrostimulation on pruritus induced by dextran in the mice].

Mutational effects of the asparagine198 and glutamate223 residues on the human norepinephrine transporter on basal and HIV-1 Tat protein-induced inhibition of dopamine transport.

The Role of Calcium-Independent Phospholipase A2 in the Molecular Mechanisms of Schizophrenia.

Molecular and neural basis of vomiting behavior in Drosophila melanogaster.

Quantitative Control of Zn2+ Photorelease: A Step toward Decoding Mechanisms of Subsecond Metal Signaling in the Brain.

Bidirectional crosstalk between microglia and serotonin signaling in neuroinflammation and CNS disorders.

Dopaminergic frontostriatal pathways in major depressive disorder and childhood sexual abuse: a multimodal neuroimaging investigation.

Fusobacterium nucleatum enhances amphetamine-induced behavioral responses through a butyrate-driven epigenetic mechanism.

Synergistic stress-relieving and cognitive-enhancing effects of walnut peptide and theanine in human brain organoid and mouse stress models.

Piezo knockdown reduces 5‑hydroxytryptamine release from enterochromaffin cells and exacerbates intestinal dyskinesia in mice with functional constipation.

Characteristics of the 18F-fluorodeoxyglucose (18F-FDG) and [18F] 9-fluoropropyl-(+)-dihydrotetrabenazine (18F-FP-DTBZ) positron emission tomography (PET) in patients with cognitive impairment in Parkinson's disease.

Acetylation of Histones in the Nucleus Accumbens Increases the Expression of Dopamine Transporters to Regulate Executive Function in Sapap3 Knockout Mice.

Cell membrane cholesterol affects serotonin transporter efflux due to altered transporter oligomerization.

Role of serotonin in the neurobiology of attention-deficit/hyperactivity disorder: a systematic literature review.

A Common Cause of ADHD and Bipolar Disorder (BD).

Engineered spermidine-secreting Saccharomyces boulardii ameliorates colitis and colon cancer in mice.

Role of Phosphorylation of Serotonin and Norepinephrine Transporters in Animal Behavior: Relevance to Neuropsychiatric Disorders.

Impact of Manganese on Neuronal Function: An Exploratory Multi-Omics Study on Ferroalloy Workers in Brescia, Italy.

Cocaine chemogenetics blunts drug-seeking by synthetic physiology.

Combinatorial effects of tryptophan derivatives serotonin and indole on virulence modulation of enteric pathogens.

Dopaminergic Modulation of Short-Term Associative Memory in Caenorhabditis elegans.

Evolution of polyamine resistance in Staphylococcus aureus through modulation of potassium transport.

Sleep Deprivation Aggravates Periodontitis Through Trigeminal-Periodontal Neuroimmune Pathway Mediated by the AChE-ACh-α7nAChR Axis.

Phenotype Differences Between ATP13A2 Heterozygous and Knockout Mice Across Aging.

Protective role of bovine lactoferrin in modulating the intestinal serotonergic system: Implications in intestinal inflammation.

Antidepressant in treating myocardial infarction complicated with depression via 5-HT/inflammation from heart to brain.

Neurotoxic significance of H2O2 generation in nigral dopaminergic damage by paraquat and protective action of effusol and dehydroeffusol, Juncus effusus ingredients.

Akkermansia muciniphila-Derived N-Acetylspermidine Modulates the Localization of Intestinal α1,2-Fucosylated Proteins to Maintain Gut Homeostasis.

Continuous Chest Compressions with Asynchronous Ventilation in Asphyxiated Preterm Lambs with Asystole.

Neural and dopaminergic substrates of festinating gait in Parkinson's disease.

Synaptic enrichment of pSer129 alpha-synuclein correlates with dopaminergic denervation in early-stage Parkinson's disease.

Focused ultrasound-triggered escitalopram delivery using microbubble-liposome complexes for rapid and sustained serotonin regulation in depression therapy.

CAD (Cath. a-Differentiated) Cells Produce Dopamine along with Dopamine-Synthesizing Enzymes.

Bromelain Alleviates Sleep Deprivation-Induced Intestinal Injury via TRPA1/5-HT Axis.

L-DOPA reverses the impaired working memory via lateral habenula Kv7.2 subunit-containing M-channels in experimental parkinsonism.

Role of Serotonin, Membrane Transporter, and 5-HT2 Receptors in Pathogenesis of Atherosclerotic Plaque Formation in Immature Heterozygous Low-Density Lipoprotein-Receptor-Deficient Mice.

Gabapentin fails to provide analgesia while duloxetine remains effective in an attention deficit hyperactivity disorder rat model with neuropathic pain.

Selective loss of Scn2a in ventral tegmental area dopaminergic neurons leads to dopamine system hypofunction and autistic-like behaviors.

Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder.

GDM enhanced acetylcholine induced vasoconstriction in human umbilical vein via CHRM3 and CACNA1C upregulation linked to promoter hypomethylation.

Short-term high-fat diet elevates oxidative stress in male but not female A53T mice without altering striatal dopaminergic markers.

A multicenter longitudinal study of cholinergic subgroups in Parkinson disease.

Association of Striatal Dopaminergic Depletion and Cerebral Perfusion With Cognition in Brain-First and Body-First Parkinson's Disease.

Effects of selective serotonin reuptake inhibitors on the placenta†.

Biased Signaling Agonists of Dopamine D3 Receptor Differentially Regulate the Effects of Cocaine On Dopamine Transporter Function.

OGG1 Preserves Endothelial-Dependent Vasodilation and Regulates the Frequency and Spatial Area of Endothelial Calcium Signals.

Pancreatic acinar cell signalling and function exhibit an absolute requirement for activation of Gαq.

PKC in the perspective of dopamine receptor signaling.

Norepinephrine system dysconnectivity in major depressive disorder: the effect of short term SSRI treatment.

Ex vivo stimulation of the trigeminal nucleus caudalis induces peripheral CGRP release in the trigeminal ganglion and reveals a distinct dopamine-endocannabinoid mechanism relevant to migraine.

A large-scale multimodal investigation of the interplay between the serotonergic system and emotion processing.

Colour discrimination deficit in REM sleep behavior disorder: an analysis of dopaminergic depletion, cognition, and brain morphology.

A gatekeeper sympathetic control of lacrimal tear secretion and dry eye onset through the NA-Adra1a-Ucp2 pathway.

Transient receptor potential vanilloid 2 (TRPV2) channels modulate the nigrostriatal dopaminergic activity in rats.

Perinatal serotonin signalling dynamically influences the development of cortical GABAergic circuits with consequences for lifelong sensory encoding.

Kv1.3 knockdown attenuates alcohol-related liver injury in mice through induction of tryptamine.

Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy.

Prenatal serotonin depletion persistently disrupts social behavior and modulates ΔFosB and SERT expression in mice.

Kappa opioid receptor antagonism restores phosphorylation, trafficking and behavior induced by a disease-associated dopamine transporter variant.

Vitamin C Transport Deficiency Alters Striatal Dopamine Gene Expression and Metabolism in YAC128 Huntington Disease Mice.

Human umbilical cord-derived mesenchymal stem cells attenate histaminergic effect of intestinal mucosa through bax/bcl-2 pathway in food allergic enteritis.

Serotonergic and Dopaminergic Function in Neuropsychiatrically Asymptomatic People With HIV on Antiretroviral Therapy.

Effect of cecal microbiota transplantation on peripheral 5-hydroxytryptamine and breast muscle glucose metabolism in long-photoperiod broilers.

Impact of Manganese on Neuronal Function: An Exploratory MultiOmic Study on Ferroalloy Workers in Brescia, Italy.

Bioproduction of a Large-Scale Library of Tryptamine Derivatives for Neuropsychiatric Drug Screening.

Inhibition of TRPM3 channels in the medial prefrontal cortex mitigates OCD symptoms following traumatic brain injury.

Glutamate-Based Therapeutic Strategies for Schizophrenia: Emerging Approaches Beyond Dopamine.

Dynamic Model of Serotonin Presynapse and Its Application to Suicide Attempt in Patients with Bipolar Disorder.

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock-In Mice.

Human and rat ex vivo sweat glands for the observation of acetylcholine induced intracellular calcium signalling.

α7nAChR on B cells directs T cell differentiation to prevent viral myocarditis.

Environmental Factors Exacerbate Parkinsonian Phenotypes in an Asian-Specific Knock-In LRRK2 Risk Variant in Mice.

[Research progress of the dopamine system in neurological diseases].

Serotonin innervation of the subthalamic nucleus in parkinsonian monkeys.

Structure and mechanism of human vesicular polyamine transporter.

Neuroregulation of histamine of circadian rhythm disorder induced by chronic intermittent hypoxia.

A comparative exploration of monoamine neurotransmitter transport disorders: mechanisms, clinical manifestations, and therapeutic approaches.

Astaxanthin Mitigates ADHD Symptoms in Spontaneously Hypertensive Rats via Dopaminergic Modulation and Brain-Gut Axis Regulation.

Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in models of LRRK2-Parkinson's disease.

Clonidine mitigates noise-induced hearing loss by regulating TRPC6-mediated calcium influx in cochlear hair cells.

Anti-central fatigue effects of myelophil in 5-HTergic hyperactivity mice model.

B cell-derived acetylcholine mitigates skin inflammation in mice through α9 nicotinic acetylcholine receptor-mediated signaling.

Sex Steroid Control of Serotonergic System: Clinical Implications for Psychiatric Disorders and Addiction Treatment.

Altered GABAergic Homeostasis in the Striatum of Dopamine Transporter Knockout Rats.

Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.

Abdominal Ultrasound Stimulation Alleviates Negative Symptoms Through Modulation of Serotonin Signaling and Gut Microbiota in the MK-801 Model of Schizophrenia.

Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A.

Past, present, and future of serotonin-targeting therapeutics for Alzheimer's disease: Perspectives from DNA methylation.

Abscisic Acid Rescues Behavior in Adult Female Mice in Attention Deficit Disorder with Hyperactivity Model of Dopamine Depletion by Regulating Microglia and Increasing Vesicular GABA Transporter Expression.

Tryptophan metabolism in migraine: a review of experimental and clinical studies and a need to enhance research strategies.

Repurposing serotonergic drugs for gastric cancer: induction of apoptosis in vitro.

Design and validation of novel brain-penetrant HCN channel inhibitors to ameliorate social stress-induced susceptible phenotype.

The selenocysteine-containing protein SELENOT maintains dopamine signaling in the midbrain to protect mice from hyperactivity disorder.

Control of pili synthesis and putrescine homeostasis in Escherichia coli.

Revisiting eye blink in Parkinson's disease.

Diallyl Trisulfide, an Active Substance from Garlic, Inhibits Female Oviposition by Decreasing the Expression of the OCT Gene, which is Highly Expressed in the Spermathecal Gland of Sitotroga cerealella (Oliver).

Therapeutic Effects of Pharmacological Modulation of Serotonin Brain System in Human Patients and Animal Models of Fragile X Syndrome.

α-Conotoxin TxIB Reversed Nicotine-Induced Locomotor Sensitization and Nicotine-Enhanced Dopaminergic Activity in Mice.

Preclinical Profile of CM699 as a Medication Candidate for Stimulant Use Disorder.

Exploring the impact of MDMA and oxytocin ligands on anxiety and social responses: A comprehensive behavioural and molecular study in the zebrafish model.

α7-Nicotinic Acetylcholine Receptor and Mutated α-Synuclein Interact in Motor Behaviour and Nigrostriatal Dopamine-Findings With Potential Relevance for a Protective Effect of Cigarette Smoking and Parkinson's Disease.

Enhancement of D1 dopaminergic responses in aged LRRK2 G2019S knock-in mice.

Unveiling the potential abuse liability of α-D2PV: A novel α-carbon phenyl-substituted synthetic cathinone.

Alarmone ppGpp modulates bacterial motility, zeamine production, and virulence of Dickeya oryzae through the regulation of and cooperation with the putrescine signaling mechanism.