Raras
Buscar doenças, sintomas, genes...
Febre de Boutonneuse
ORPHA:83313CID-10 · A77.1CID-11 · 1C31.1DOENÇA RARA

Doença infecciosa da região do Mediterrâneo, Crimeia, África e Índia, causada por infecção por Rickettsia conorii subsp. coronarii.

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Introdução

O que você precisa saber de cara

📋

Doença infecciosa da região do Mediterrâneo, Crimeia, África e Índia, causada por infecção por Rickettsia conorii subsp. coronarii.

Publicações científicas
285 artigos
Último publicado: 2023 Nov 9

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-5 / 10 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
24.2
France
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: A77.1
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Do básico ao detalhe, leia no seu ritmo

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧬
Pele e cabelo
5 sintomas
🫃
Digestivo
4 sintomas
🩸
Sangue
4 sintomas
🫘
Rins
1 sintomas
👁️
Olhos
1 sintomas
🫁
Pulmão
1 sintomas

+ 9 sintomas em outras categorias

Características mais comuns

90%prev.
Erupção cutânea
Muito frequente (99-80%)
90%prev.
Anormalidade da pele da palma da mão
Muito frequente (99-80%)
90%prev.
Febre
Muito frequente (99-80%)
90%prev.
Morfologia anormal da pele plantar do pé
Muito frequente (99-80%)
55%prev.
Linfadenopatia
Frequente (79-30%)
55%prev.
Descolamento da pele
Frequente (79-30%)
26sintomas
Muito frequente (4)
Frequente (13)
Ocasional (6)
Muito raro (3)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 26 características clínicas mais associadas, ordenadas por frequência.

Erupção cutâneaSkin rash
Muito frequente (99-80%)90%
Anormalidade da pele da palma da mãoAbnormality of the skin of the palm
Muito frequente (99-80%)90%
FebreFever
Muito frequente (99-80%)90%
Morfologia anormal da pele plantar do péAbnormality of the plantar skin of foot
Muito frequente (99-80%)90%
LinfadenopatiaLymphadenopathy
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa3desde 2023
Total histórico285PubMed
Últimos 10 anos127publicações
Pico201519 papers
Linha do tempo
2023Hoje · 2026📈 2015Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

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Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

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Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

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Publicações mais relevantes

Timeline de publicações
11 papers (10 anos)
#1

Identification of Rickettsia conorii Indian tick typhus strain in a Patient and an Attached Rhipicephalus turanicus Tick in Xinjiang, China.

Ticks and tick-borne diseases2026 Mar

Rickettsia conorii Indian tick typhus strain (R. conorii subsp. indica, ITTR) was detected in both a human patient and an attached Rhipicephalus turanicus tick that was removed from the patient in Yanqi County, Xinjiang Uygur Autonomous Region (XUAR), China. The molecular identification of the pathogen, along with previous reports, suggests it may be distributed across the area. A 55-year-old female farmer presented with fever, headache, eschar, and a maculopapular rash following a tick bite. Laboratory findings indicated thrombocytopenia, liver enzyme elevation, and proteinuria, which, combined with clinical symptoms, strongly suggested a rickettsial infection. PCR and sequencing of multiple rickettsial genes confirmed the presence of ITTR in both the patient and the tick. Furthermore, the genetic identity between these sequences provided evidence that R. turanicus can act as a vector of ITTR. This case provides valuable insights into the clinical manifestation, diagnosis, and treatment of ITTR infections. These findings highlight the need for improved surveillance and awareness of tick-borne rickettsial diseases in regions with high tick exposure.

#2

High prevalence of the Mediterranean spotted fever agent Rickettsia aeschlimannii in Hyalomma marginatum ticks from Pianosa island, Italy.

Parasites &amp; vectors2026 Feb 03

Tick-borne rickettsioses, caused by bacteria of the spotted fever group (SFG) Rickettsia, are emerging infectious diseases whose emergence and spread are often affected by climate and land-use changes. Here, we report the results of monitoring Hyalomma spp. ticks in the protected area of Pianosa island (Tuscany (Italy) and subsequently investigating their bacterial community through metabarcoding sequencing. In this study, based on analyses of 575 tick specimens distributed in 120 pools, we recorded a high prevalence of Rickettsia aeschlimannii (58% and 75% gltA- and 17 kDa-Ag protein-positive pools, respectively), an agent of the SFG group in H. marginatum. These findings support the need for warnings on the risk of transmission of spotted fever rickettsiosis to both residents and visitors and underline the need for enhanced surveillance, public awareness and preventive measures.

#3

[A case of Guillain-Barré syndrome due to infection with Rickettsia conorii in Tunisia].

Medecine tropicale et sante internationale2025 Dec 31

Mediterranean spotted fever is an infection caused by Rickettsia conorii that is endemic to the Mediterranean basin. It is mainly transmitted by ticks. The association between this infection and Guillain-Barre syndrome (GBS) is uncommon. We present the case of a 29-year-old Tunisian patient with no prior medical conditions who presented with flaccid quadriplegia that progressed to respiratory distress. This was accompanied by persistent fever and hepatosplenomegaly. Acute motor axonal GBS was diagnosed through electroneuromyography, and R. conorii infection was diagnosed through serology. Treatment with immunoglobulins and doxycycline led to gradual clinical improvement. This case underscores the importance of considering R. conorii infection in patients with GBS presenting with systemic symptoms, especially in endemic regions like Tunisia. La fièvre boutonneuse méditerranéenne, causée par Rickettsia conorii, est une infection endémique dans le bassin méditerranéen, transmise principalement par les tiques. L’association entre cette infection et le syndrome de Guillain-Barré (SGB) est rare. Nous rapportons le cas d’un patient tunisien de 29 ans, sans antécédents médicaux, présentant une quadriplégie flasque évoluant vers une détresse respiratoire, associée à une fièvre persistante et une hépatosplénomégalie. Le diagnostic de SGB sous sa forme axonale motrice aiguë, a été confirmé par électroneuromyogramme et l’infection à R. conorii par la sérologie. Le traitement par immunoglobulines et doxycycline a conduit à une amélioration clinique progressive. Ce cas souligne l’importance de penser à l’infection à R. conorii, devant un SGB associé à des signes systémiques en particulier dans un pays endémique comme la Tunisie.

#4

Haemophagocytic lymphohistiocytosis triggered by Rickettsia conorii.

Transactions of the Royal Society of Tropical Medicine and Hygiene2025 Nov 03

Haemophagocytic lymphohistiocytosis (HLH) is a rare complication of rickettsial infections. We report a 50-y-old man from northern India who presented with fever, respiratory distress, altered sensorium and an eschar. Despite treatment with doxycycline, his condition deteriorated with multi-organ dysfunction. PCR and sequencing from the eschar confirmed Rickettsia conorii. Bone marrow examination, elevated ferritin and triglycerides, as well as an H-score of 224 confirmed HLH. The patient was treated with corticosteroids but succumbed to refractory ventricular arrhythmias. A high index of suspicion is essential in rickettsial infections that present with multi-organ dysfunction, as early recognition of HLH enables the prompt initiation of treatment of the underlying disease and adjunctive immunosuppressive therapy. [GenBank accession nos. U59728.1 and MZ779037.].

#5

Rickettsiosis cases presenting with rash: a case series from an endemic region in Turkey.

Revista do Instituto de Medicina Tropical de Sao Paulo2025

Rickettsia species are Gram-negative, pleomorphic coccobacilli that are obligate intracellular pathogens transmitted by arthropod vectors such as ticks. Among them, Rickettsia conorii, the causative agent of Mediterranean spotted fever (MSF), is endemic in many Mediterranean countries, including Turkey. This case series describes three patients from Balıkesir, Turkey, who developed high-grade fever, generalized maculopapular rash involving the palms and feet soles, arthralgia, and necrotic eschars (tache noire) at the tick bite sites. All cases occurred during summer and had documented exposure to Rhipicephalus sanguineus. Laboratory evaluations ruled out other tick-borne diseases, while real-time PCR performed on skin biopsy samples confirmed Rickettsia spp. Subsequent DNA sequencing of the gltA and ompA gene regions enabled species identification. Additionally, serological tests showed a significant rise in IgM and IgG antibody titers reacting with Rickettsia conorii antigen by indirect immunofluorescence assay. All patients were treated with doxycycline and recovered without complications. This case series highlights the importance of considering rickettsial infections in the differential diagnosis of febrile patients with rash and recent tick exposure, especially in endemic regions during warm seasons.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC225 artigos no totalmostrando 125

2025

[A case of Guillain-Barré syndrome due to infection with Rickettsia conorii in Tunisia].

Medecine tropicale et sante internationale
2026

Identification of Rickettsia conorii Indian tick typhus strain in a Patient and an Attached Rhipicephalus turanicus Tick in Xinjiang, China.

Ticks and tick-borne diseases
2026

High prevalence of the Mediterranean spotted fever agent Rickettsia aeschlimannii in Hyalomma marginatum ticks from Pianosa island, Italy.

Parasites &amp; vectors
2025

Haemophagocytic lymphohistiocytosis triggered by Rickettsia conorii.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2025

Rickettsiosis cases presenting with rash: a case series from an endemic region in Turkey.

Revista do Instituto de Medicina Tropical de Sao Paulo
2025

Seroepidemiology of Rickettsia conorii in dogs in Portugal: a comprehensive 12-year retrospective study (2013-2024).

Parasites &amp; vectors
2025

Challenges in Diagnosing Rickettsial Infection: A Case Report of Rickettsia conorii in a Pediatric Patient in Iran.

The Pediatric infectious disease journal
2024

Epidemiology and clinical characteristics of Mediterranean spotted fever suspects in a university hospital, Tunisia, 2000-2020.

Epidemiology and infection
2024

A case series of Mediterranean spotted fever and murine typhus with neurological manifestations.

Journal of vector borne diseases
2024

Identifying New Areas of Endemicity and Risk Factors for Rickettsia conorii subsp. conorii Infection: Serosurvey in Rural Areas of Romania.

Pathogens (Basel, Switzerland)
2024

The case of Mediterranean spotted fever of the traveler returned from Zambia.

Ticks and tick-borne diseases
2024

A Case of Mediterranean Spotted Fever with Cerebral Infarction.

Vector borne and zoonotic diseases (Larchmont, N.Y.)
2024

Ehrlichia canis and Rickettsia conorii Infections in Shelter Dogs: Seropositivity and Implications for Public Health.

Pathogens (Basel, Switzerland)
2024

Serological and molecular epidemiological investigation of Mediterranean spotted fever in Yunnan Province, China.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
2024

Rickettsia conorii subsp. israelensis infection in a pediatric patient presenting skin rash and abdominal pain: a case report from Southeast Iran.

BMC infectious diseases
2024

Mediterranean spotted fever.

Medicina clinica
2023

Boutonneuse Fever in Southeastern Romania.

Microorganisms
2023

Introduction of the ectoparasite Rhipicephalus pulchellus (Ixodida: Ixodidae) into Connecticut with a human traveler from Tanzania, and a review of its importation records into the United States.

Journal of medical entomology
2024

Swept-source optical coherence tomography angiography in Mediterranean spotted fever retinitis with retinal vasculitis.

Journal francais d'ophtalmologie
2023

Concurrent Visual and Auditory Deficits in a Patient with Rickettsia conorii Infection.

The American journal of tropical medicine and hygiene
2023

Hemophagocytic syndrome secondary to Mediterranean spotted fever.

Medicina clinica
2023

Fatal complicated infection by Rickettsia conorii: role of cerebral involvement, antiphospholipid antibodies, and multiple comorbidities.

Recenti progressi in medicina
2022

IL-1 Superfamily Member (IL-1A, IL-1B and IL-18) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever.

Biomolecules
2022

Mediterranean spotted fever with multiorgan involvement.

BMJ case reports
2022

A case of Mediterranean spotted fever mimicking severe sepsis.

Journal of vector borne diseases
2022

Natural Mediterranean Spotted Fever Foci, Qingdao, China.

Emerging infectious diseases
2022

Mediterranean spotted fever-like illness caused by Rickettsia sibirica mongolitimonae, North Macedonia, June 2022.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2024

Rickettsia conorii: Unusual case of acute aortic thrombosis.

Vascular
2022

An update on spotted fever group serology in Kerman Province, Iran.

Comparative immunology, microbiology and infectious diseases
2022

Mediterranean spotted fever and peripheral facial nerve palsy: a rare neurological complication.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2022

Fatal Case of Mediterranean Spotted Fever Associated with Septic Shock, Iran.

Emerging infectious diseases
2022

Clinical case report: Not all rickettsiosis are mediterranean spotted fever.

Enfermedades infecciosas y microbiologia clinica (English ed.)
2021

Confirmation of Rickettsia conorii Subspecies indica Infection by Next-Generation Sequencing, Shandong, China.

Emerging infectious diseases
2022

A severe case of Israeli spotted fever with pleural effusion in Italy.

Infection
2021

Concomitant Mediterranean spotted fever and systemic lupus erythematosus: a rare case report.

The Pan African medical journal
2021

[Mediterranean spotted fever in immunosuppressed patients].

Semergen
2021

Acute disseminated encephalomyelitis due to Rickettsia conorii infection.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
2021

Renal Involvement in Mediterranean Spotted Fever: Clinical and Histopathological Data.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre
2021

Recent advances in understanding tick and rickettsiae interactions.

Parasite immunology
2021

Mediterranean spotted fever associated with leucocytoclastic vasculitis and acute pancraeatitis.

BMJ case reports
2021

Septic shock by Rickettsia conorii.

Medicina clinica
2020

Mediterranean spotted fever in child and adult patients: investigation from an endemic region in Bulgaria.

Central European journal of public health
2020

[Mediterranean spotted fever or DEBONEL?].

Anales de pediatria
2020

Early Findings of Rickettsioses in Morocco.

Journal of vector borne diseases
2020

Survival of Rickettsia conorii in artificially contaminated whole and leukoreduced canine blood units during the storage period.

Parasites &amp; vectors
2020

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections.

The American journal of pathology
2020

Spatial and temporal trends of Mediterranean spotted fever in Spain, 2005-2015.

Ticks and tick-borne diseases
2019

South African Tick Bite Fever: An Overview.

Dermatopathology (Basel, Switzerland)
2020

[Fever and eruption in 2 neighbors].

Atencion primaria
2019

Rickettsial infections of the central nervous system.

PLoS neglected tropical diseases
2019

Seroprevalences of Rickettsia conorii, Ehrlichia canis and Coxiella burnetii in Dogs from Montenegro.

Acta parasitologica
2019

[Retrospective serological diagnostics of spotted fever group rickettsioses in high risk areas of Rickettsia conorii subsp. Caspia infection.].

Klinicheskaia laboratornaia diagnostika
2019

Mediterranean spotted fever in the elderly: a prospective cohort study.

European journal of clinical microbiology &amp; infectious diseases : official publication of the European Society of Clinical Microbiology
2019

Risk factors for bacterial zoonotic pathogens in acutely febrile patients in Mpumalanga Province, South Africa.

Zoonoses and public health
2019

Global Transcriptomic Profiling of Pulmonary Gene Expression in an Experimental Murine Model of Rickettsia conorii Infection.

Genes
2019

[Macular atrophy secondary to bilateral involvement in Mediterranean spotted fever].

Journal francais d'ophtalmologie
2020

[Mediterranean spotted fever in a 3-year-old boy treated with doxycycline].

Anales de pediatria
2018

Spotted fever rickettsioses causing myocarditis and ARDS: a case from Sri Lanka.

BMC infectious diseases
2018

[A Rickettsia case caused by Rickettsia conorii].

Mikrobiyoloji bulteni
2019

Unusual Maculopapular Rash on the Scalp of a Patient with Mediterranean Spotted Fever.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre
2018

Ocular manifestations of Rickettsia conorii in South India.

Indian journal of ophthalmology
2018

Tick- and flea-borne rickettsioses in Tizi-Ouzou, Algeria: Implications for travel medicine.

Travel medicine and infectious disease
2019

Mediterranean spotted fever rickettsiosis in Italy, 2001-2015: Spatio-temporal distribution based on hospitalization records.

Ticks and tick-borne diseases
2018

Prospective Cohort Study of Single-Day Doxycycline Therapy for Mediterranean Spotted Fever.

Antimicrobial agents and chemotherapy
2018

[A complicated clinical course of tick-borne rickettsiosis after safari in South Africa].

Deutsche medizinische Wochenschrift (1946)
2018

[Haemophagocytic syndrome secondary to Mediterranean spotted fever].

Annales de dermatologie et de venereologie
2018

Mediterranean Spotted Fever in Children: Study of a Portuguese Endemic Region.

Acta medica portuguesa
2018

Rare presentation of rickettsial infection as purpura fulminans: a case report.

Journal of medical case reports
2018

Ocular manifestations of rickettsia in children: common but frequently overlooked.

BMJ case reports
2018

[Intraocular manifestations of Rickettsia conorii infection: A case report].

Journal francais d'ophtalmologie
2019

Graft-versus-host disease after an infection by Rickettsia conorii induced by a tick's bite.

Medicina clinica
2018

Prophylaxis in case of tick bite in Provence-Alpes-Côte d'Azur.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
2018

Under-diagnosis of rickettsial disease in clinical practice: A systematic review.

Travel medicine and infectious disease
2018

Clinically-diagnosed Mediterranean Spotted Fever in Malta.

Travel medicine and infectious disease
2018

Tache Noire in a Patient with Acute Q Fever.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre
2018

Black spot or «tache noire» in mediterranean spotted fever.

Medicina clinica
2018

[Symmetrical peripheral gangrene: 4 cases].

Annales de dermatologie et de venereologie
2017

First detection of Rickettsia conorii ssp. caspia in Rhipicephalus sanguineus in Zambia.

Parasitology research
2017

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium.

PloS one
2019

Postfebrile telogen effluvium: hair fall after Rickettsia conorii infection.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia
2017

[Rickettsiosis associated with cerebral infarction: a new case study].

The Pan African medical journal
2017

[Branch retinal artery occlusion in a child: A typical manifestation of rickettsiosis].

Journal francais d'ophtalmologie
2018

Rickettsia conorii: Unusual cause of diarrhoea.

Gastroenterologia y hepatologia
2017

Israeli Spotted Fever in Sicily. Description of two cases and minireview.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2017

Epidemiological evaluation of Mediterranean spotted fever in children of the Karak province in south Jordan.

Journal of infection in developing countries
2017

Mediterranean spotted fever in Spain, 1997-2014: Epidemiological situation based on hospitalization records.

PloS one
2016

[Late diagnosis of fatal invasive rickettsial disease in the Intensive Care Unit].

The Pan African medical journal
2017

Mediterranean Spotted Fever: A Rare Non-Endemic Disease in the USA.

Cureus
2017

"Tache noire": diagnostic clue in a febrile exanthem.

Medicina clinica
2016

Chronic inflammatory demyelinating polyneuropathy associated with Rickettsia conorii: First case report.

Journal of the neurological sciences
2016

Small Regulatory RNAs of Rickettsia conorii.

Scientific reports
2016

Rickettsiae and rickettsial diseases in Croatia: Implications for travel medicine.

Travel medicine and infectious disease
2016

Macrophagic activation syndrome related to an infection by Rickettsia conorii in a child.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
2016

Survey of Zoonoses in Extremadura, Spain.

Japanese journal of infectious diseases
2016

Scrub typhus and spotted fever among hospitalised children in South India: Clinical profile and serological epidemiology.

Indian journal of medical microbiology
2016

Malignant forms of Mediterranean spotted fever: risk factors for fatal outcomes.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
2016

Mediterranean spotted fever-like illness in Sardinia, Italy: a clinical and microbiological study.

Infection
2016

Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2016

Spotted fever group rickettsiae in ticks of migratory birds in Romania.

Parasites &amp; vectors
2016

Rickettsia parkeri colonization in Amblyomma maculatum: the role of superoxide dismutases.

Parasites &amp; vectors
2016

High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation.

Cytokine
2015

T-Lymphocyte Subset Absolute Counts in the Peripheral Blood of Mediterranean Spotted Fever Patients: Relations to Disease Severity.

Folia medica
2016

Severe Israeli spotted fever with multiorgan failure in a child.

Ticks and tick-borne diseases
2016

Prevalence of antibodies to Rickettsia conorii in human beings and dogs from Catalonia: a 20-year perspective.

Epidemiology and infection
2016

Shell-vial culture, coupled with real-time PCR, applied to Rickettsia conorii and Rickettsia massiliae-Bar29 detection, improving the diagnosis of the Mediterranean spotted fever.

Ticks and tick-borne diseases
2015

Characterization of spotted fever group Rickettsiae in ticks from a city park of Rome, Italy.

Annali dell'Istituto superiore di sanita
2016

Nonselective Persistence of a Rickettsia conorii Extrachromosomal Plasmid during Mammalian Infection.

Infection and immunity
2015

[ON THE ROLE OF RICKETTSIA RAOULTII IN THE EPIDEMIOLOGY OF RICKETTSIOSES IN RUSSIA].

Meditsinskaia parazitologiia i parazitarnye bolezni
2015

Randomized Trial of Clarithromycin for Mediterranean Spotted Fever.

Antimicrobial agents and chemotherapy
2015

[Mediterranean Spotted Fever: Retrospective Review of Hospitalized Cases and Predictive Factors of Severe Disease].

Acta medica portuguesa
2015

[Guillain-Barré syndrome. Early ultrasound findings].

Revista de neurologia
2015

Evaluation of a new serological test for the detection of anti-Coxiella and anti-Rickettsia antibodies.

Microbes and infection
2015

Rickettsia massiliae and Rickettsia conorii Israeli Spotted Fever Strain Differentially Regulate Endothelial Cell Responses.

PloS one
2015

[Mediterranean Spotted Fever: epidemiological Assessment in Spain during the Period 2009-2012].

Revista espanola de salud publica
2015

A case of Mediterranean spotted fever associated with severe respiratory distress syndrome.

Microbes and infection
2015

Mediterranean spotted fever with lymphangitis occurring from a tick bite lesion. A case in Spain.

International journal of dermatology
2015

Mediterranean spotted fever: an unusual clinical and neuroradiological presentation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2015

Causes of Fever in Rural Southern Laos.

The American journal of tropical medicine and hygiene
2015

Parinaud's oculoglandular syndrome revealing subclinical Rickettsia conorii infection.

International ophthalmology
2015

The role of Rhipicephalus sanguineus sensu lato saliva in the dissemination of Rickettsia conorii in C3H/HeJ mice.

Medical and veterinary entomology
2015

Mediterranean spotted fever and hearing impairment: a rare complication.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2014

[South African tick bite fever in a group of Russian tourists].

Terapevticheskii arkhiv
2015

Unlocking proteomic heterogeneity in complex diseases through visual analytics.

Proteomics
2015

Relative sensitivity of conventional and real-time PCR assays for detection of SFG Rickettsia in blood and tissue samples from laboratory animals.

PloS one
2015

Rickettsial infection caused by accidental conjunctival inoculation.

BMJ case reports
Ver todos os 225 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Identification of Rickettsia conorii Indian tick typhus strain in a Patient and an Attached Rhipicephalus turanicus Tick in Xinjiang, China.
    Ticks and tick-borne diseases· 2026· PMID 41650674mais citado
  2. High prevalence of the Mediterranean spotted fever agent Rickettsia aeschlimannii in Hyalomma marginatum ticks from Pianosa island, Italy.
    Parasites &amp; vectors· 2026· PMID 41634780mais citado
  3. [A case of Guillain-Barr&#xe9; syndrome due to infection with Rickettsia conorii in Tunisia].
    Medecine tropicale et sante internationale· 2025· PMID 41768953mais citado
  4. Haemophagocytic lymphohistiocytosis triggered by Rickettsia conorii.
    Transactions of the Royal Society of Tropical Medicine and Hygiene· 2025· PMID 40693676mais citado
  5. Rickettsiosis cases presenting with rash: a case series from an endemic region in Turkey.
    Revista do Instituto de Medicina Tropical de Sao Paulo· 2025· PMID 40608626mais citado
  6. Boutonneuse Fever in Southeastern Romania.
    Microorganisms· 2023· PMID 38004746recente
  7. Introduction of the ectoparasite Rhipicephalus pulchellus (Ixodida: Ixodidae) into Connecticut with a human traveler from Tanzania, and a review of its importation records into the United States.
    J Med Entomol· 2023· PMID 37963278recente
  8. Boutonneuse Fever.
    · 2026· PMID 32809749recente
  9. Recent advances in understanding tick and rickettsiae interactions.
    Parasite Immunol· 2021· PMID 33713348recente
  10. Mediterranean spotted fever in child and adult patients: investigation from an endemic region in Bulgaria.
    Cent Eur J Public Health· 2020· PMID 32997473recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:83313(Orphanet)
  2. MONDO:0024472(MONDO)
  3. GARD:19031(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q895297(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Febre de Boutonneuse
Compêndio · Raras BR

Febre de Boutonneuse

ORPHA:83313 · MONDO:0024472
Prevalência
1-5 / 10 000
Herança
Not applicable
CID-10
A77.1 · Febre maculosa por Rickettsia conorii
CID-11
Início
All ages
Prevalência
24.2 (France)
MedGen
UMLS
C0006060
Repurposing
22 candidatos
aspirincyclooxygenase inhibitor
chloramphenicolbacterial 50S ribosomal subunit inhibitor
chloramphenicol-palmitateprotein synthesis inhibitor
+17 outros
EuropePMC
Wikidata
Papers 10a
DiscussaoAtiva

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