Lesões na medula espinhal, com ou sem perfuração, causadas por forças externas violentas (por exemplo, ferimentos por arma de fogo; lesões de chicote; etc.).
Introdução
O que você precisa saber de cara
Lesões na medula espinhal, com ou sem perfuração, causadas por forças externas violentas (por exemplo, ferimentos por arma de fogo; lesões de chicote; etc.).
Tem tratamento?
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 10 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 15 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Lesão traumática da medula espinhal
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Publicações mais relevantes
Mostrando amostra de 200 publicações de um total de 28.272
Ddx20, DEAD-box helicase 20 is essential for maintaining microglial homeostasis.
Este estudo identifica que uma proteína, a Ddx20, é essencial para manter a saúde e o funcionamento adequado das micróglias, as células de defesa do cérebro e da medula espinhal. A ausência de Ddx20 compromete seriamente a capacidade dessas células de proteger e reparar o sistema nervoso, com efeitos mais graves após lesões na medula espinhal e com o envelhecimento. Essa descoberta aponta para o Ddx20 como um potencial novo alvo para desenvolver futuras terapias que melhorem a recuperação e o manejo de pacientes com lesão medular.
🇧🇷 traduzidoRepurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery After SCI.
Este estudo sugere que a dexmedetomidina, um medicamento já aprovado pela FDA, pode induzir uma hipotermia farmacológica rápida e sustentada após uma lesão medular (LM). Em modelos animais, esta abordagem, que combina hipotermia com neuroproteção intrínseca, demonstrou ser superior ao resfriamento convencional, promovendo uma recuperação significativamente maior das funções locomotora e vesical. Isso a torna uma estratégia terapêutica promissora, imediatamente aplicável clinicamente e sem a necessidade de equipamentos complexos para pacientes com LM aguda.
🇧🇷 traduzidoCentral and peripheral neuroplasticity in cervical spinal cord injury following intensive upper limb motor training: a randomised controlled trial protocol.
Este estudo clínico randomizado (RCT) investiga se um treinamento intensivo e adicional dos membros superiores pode melhorar a recuperação neurofisiológica e funcional em pacientes com lesão medular cervical subaguda. O objetivo é comparar seis horas extras de treino motor semanal, focado em objetivos, com o cuidado padrão, visando otimizar a função dos braços e determinar a "dose" mais eficaz de treinamento para a recuperação. Isso é crucial para pacientes, pois busca melhores resultados funcionais, e para médicos, para otimizar protocolos de reabilitação.
🇧🇷 traduzidoExosome-Loaded Engineered circBDNF Promotes Spinal Cord Injury Repair Through the PI3K/AKT/mTOR Signaling Axis.
Este estudo inovador desenvolveu uma estratégia para tratar lesões na medula espinhal (LME) utilizando exossomos que entregam uma versão modificada do fator neurotrófico BDNF (circBDNF), superando a barreira hematoencefálica. Em modelos experimentais, essa abordagem demonstrou melhorar significativamente a recuperação da função motora e a coordenação, além de promover a regeneração de nervos e reduzir danos como inflamação e morte celular na área lesionada. Tal avanço oferece uma promissora e relevante via terapêutica para pacientes com LME, justificando futuras pesquisas clínicas.
🇧🇷 traduzidoLiproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation.
Para pacientes e médicos, este estudo revela que o tratamento com Liproxstatin-1 após uma lesão medular aguda (LMA) em ratos melhora significativamente a recuperação funcional, como a função motora e o equilíbrio. Ele age inibindo a ferroptose, um tipo de morte celular dependente de ferro, e a inflamação que ela induz, resultando na redução da perda de tecido e de neurônios. Esses achados são promissores, indicando que a ferroptose é um alvo terapêutico inovador para neuroproteção e melhores desfechos em pacientes com LMA.
🇧🇷 traduzidoPublicações recentes
Immediate Consequences of a Spinal Cord Injury During Development: Unique Insights From Ex Vivo Models.
Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar-Limited Repair in Adult Spinal Cord Injury.
Duodenal perforation following right nephrectomy in a paraplegic patient with pyonephrosis: a case report and clinical insights.
Case Report: Transverse myelitis following CAR-T cell therapy for post-transplant lymphoproliferative disorder.
The Minimal Detectable Change for Balance and Balance Confidence After Chronic Spinal Cord Injury.
📚 EuropePMC32.037 artigos no totalmostrando 196
Spinal Cord Perfusion Pressure Monitoring after Traumatic Spinal Cord Injury: Indications, Techniques, and Future Horizons.
Journal of neurotraumaExosome Cargo Molecules and NLRP3/BDNF: Clinical and Preclinical Evidence for Acupuncture-Mediated Spinal Cord Injury Recovery.
International journal of general medicineCystometry Is Associated With Reduced Overall Mortality in Veterans With Suprasacral Spinal Cord Injury or Disease.
Neurourology and urodynamicsInhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury.
Communications biologyDevelopment of the PedsADAPSS: A Measure of Disability Appraisals in Youth with Spinal Cord Injury.
Archives of physical medicine and rehabilitationIntrathecal baclofen pump complications in adults: rates, risk factors, and spinal cord injury insights from a longitudinal cohort study.
Journal of neurosurgery. SpineThe posterior approach for removal of all thoracic disc herniations: a single-surgeon experience using the partial transpedicular approach with ultrasonic bone aspiration and ultrasound guidance in 108 consecutive patients.
Journal of neurosurgery. SpinePosttraumatic syrinx resulting in syringomyelia and syringobulbia: illustrative case.
Journal of neurosurgery. Case lessons20-Deoxyingenol alleviates ferroptosis by activating transcription factor EB in spinal cord injury.
NeuroreportMortality following surgical management of traumatic sub-axial cervical spine injuries in a South African tertiary centre.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research SocietyAndorra as a living lab? The inSCI example.
Journal of rehabilitation medicineProlonged Repetitive Trans-Spinal Magnetic Stimulation Promotes Superior Functional Recovery After Severe Spinal Cord Injury in Rats.
Journal of neurotraumaDeciphering hub genes and immune landscapes related to neutrophil extracellular traps in spinal cord injury: insights from integrated bioinformatics analyses and experiments.
Frontiers in immunologyThe Patient Persona of the Self-Management Experience of Home-Based Rehabilitation for Spinal Cord Injury Patients: A Qualitative Study [Letter].
Patient preference and adherencePredicting recovery trajectories and injury severity following partial crush spinal cord injury in mice.
bioRxiv : the preprint server for biologyIntegrated Multi-Omics Analysis Reveals IRF1-Driven Microglial PANoptosis via ZBP1 in Spinal Cord Injury.
Journal of inflammation researchSpinal cord disease following CAR T-cell therapy with axicabtagene ciloleucel in a patient with high-grade B-cell lymphoma.
Leukemia & lymphomaEffects of an Individualized Dietitian-Led Nutrition Intervention on Body Composition During the First Year After Traumatic Spinal Cord Injury: A Randomized Controlled Trial.
Clinical nutrition ESPENMechanism of Qufeng Huoxue decoction in treating paclitaxel-induced peripheral neuropathy based on network pharmacology and molecular docking.
NeuropeptidesCombined PLGA scaffolds and therapeutic stem cells for locomotion recovery in spinal cord-injured rats: a systematic review and meta-analysis.
Scientific reportsBridging cortical intentions: brain-computer interfaces for spinal cord injury recovery.
Science bulletinDdx20, DEAD-box helicase 20 is essential for maintaining microglial homeostasis.
Experimental neurologyAPP as an innate injury-response molecule.
Neurobiology of diseaseCurrent applications of radiomics in neurotrauma.
Neurosurgical reviewAdvances in Microenvironment-Responsive Biomaterials for Spinal Cord Injury Repair.
Advanced healthcare materialsAlternative Splicing in Central Nervous System: Molecular Mechanisms and Pathophysiological Roles.
Current neuropharmacologyTherapeutic alliance in spinal cord injury rehabilitation: power, institutions, and disabling control.
Physiotherapy theory and practiceReturn to Work After Isolated Spinal Injury: Rates, Predictors, and Implications for Occupational Reintegration.
Journal of occupational rehabilitationPreliminary efficacy of cognitive multisensory rehabilitation for neuropathic pain in chronic spinal cord injury: a phase I randomized controlled trial.
Scientific reportsCorrigendum to "Endplate chondrocyte-derived exosomal miR-128-3p mitigates intervertebral disc degeneration by targeting TRAF6 via the miR-128-3p/TRAF6 axis to suppress pyroptosis" [Int. Immunopharmacol. 143(Part 3) (2024) 113620].
International immunopharmacologyPerinatal Post-Anoxic Spinal Cord Injury: A Barrier to Pallidal Neuromodulation? About 2 Cases.
Movement disorders clinical practiceRepurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery After SCI.
The Journal of neuroscience : the official journal of the Society for NeuroscienceSex-based differences in early neurological recovery after traumatic spinal cord injury.
The journal of trauma and acute care surgeryTranscutaneous spinal cord stimulation plus locomotor training versus sham-stimulation plus locomotor training in chronic spinal cord injury (eWALK): a multicentre, triple-blind, randomised, sham-controlled trial.
EClinicalMedicineComplete Liberation from Mechanical Ventilation Using Diaphragm Pacing in a Patient with Traumatic Spinal Cord Injury Despite Persistent Unilateral Diaphragmatic Paralysis.
NMC case report journalResearch Progress on the Pyroptosis Mechanism and Related Active Ingredients of Natural Drugs in Spinal Cord Injury.
International journal of general medicineCentral and peripheral neuroplasticity in cervical spinal cord injury following intensive upper limb motor training: a randomised controlled trial protocol.
BMJ openFeasibility of AI-driven multichannel FES-assisted gait and cycling training in chronic neurological disorders: a case series.
Journal of neuroengineering and rehabilitationSchwannosis with mature collagen in the spinal cord of a calf.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, IncExosome-Loaded Engineered circBDNF Promotes Spinal Cord Injury Repair Through the PI3K/AKT/mTOR Signaling Axis.
CNS neuroscience & therapeuticsEmployment status and barriers to workforce participation among individuals with spinal cord injury: results from the Turkish InSCI Community Survey.
Spinal cordLiproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation.
Molecular and cellular neurosciencesHistone H3K9 lactylation activates the TXNIP/NLRP3 pathway to drive macrophage inflammation after spinal cord injury.
Redox biologyUlnar compound muscle action potentials predict hand muscle strength 1 year after cervical spinal cord injury: a retrospective analysis.
Annals of physical and rehabilitation medicineVocational rehabilitation for traumatic injuries: a survey of current practice and training needs of Australian allied health clinicians.
Brain impairment : a multidisciplinary journal of the Australian Society for the Study of Brain ImpairmentExperimental paralysis therapy sparks debate in Brazil.
Science (New York, N.Y.)Combined repetitive transcranial magnetic stimulation and functional electrical stimulation cycling to improve lower extremity function following incomplete spinal cord injury: Protocol for a pilot randomized controlled trial.
PloS oneIntraspinal Microstimulation of Dorsolateral Funiculus for Coordinated Bladder Control.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology SocietyCritical Considerations for Mesenchymal Stem Cell-based Therapies in Osteoarthritis and Spinal Cord Injury: A Narrative Review.
Aging and diseaseMidkine Overexpression Promotes Functional Recovery After Spinal Cord Injury by Enhancing Microglial Efferocytosis Via LRP-1.
CNS neuroscience & therapeuticsPostinjury Carnosine Treatment Prevents Neurotrophic Factor Decline in Denervated Muscle and Spinal Cord After Traumatic Injury.
The European journal of neurosciencePrevalence of Neurogenic Bowel and Lower Urinary Tract Dysfunctions in Brazilians With Traumatic and Nontraumatic Spinal Cord Injury.
Topics in spinal cord injury rehabilitationObacunone Promotes Functional Recovery After Spinal Cord Injury by Attenuating Neuroinflammation by Targeting the TLR4/MyD88/p38 MAPK Pathway.
Drug design, development and therapySimulated closed-loop magnetic stimulation promotes function recovery and axonal regeneration in spinal cord injury.
Communications biologyAnti-inflammatory treatment confirms rsfMRI and TSPO PET as biomarkers of functional connectivity and neuroinflammation in rat contusion spinal cord injuries.
Scientific reportsUpdate, translation, cross-cultural adaptation, and validation of Nottingham Stroke Dressing Assessment into Spanish.
Scientific reportsEfficacy of Minocycline in Acute Traumatic Spinal Cord Injury.
Journal of neurotraumaEmergency spinal stabilization in polytrauma: A clinical marker for tracheostomy rather than an independent risk factor for prolonged ventilation.
InjuryPTGS2 as a potential target for apigenin to promote spinal cord injury repair.
Journal of bioenergetics and biomembranesUrinary Symptoms and Sexual Dysfunction in National Level Wheelchair Rugby Male Athletes With Spinal Cord Injury.
Neurourology and urodynamicsMultimorbidity patterns in elderly sleep disordered breathing patients.
ERJ open researchDifferent approach to bone mineral density in non-traumatic spinal cord injury: a comparison with traumatic spinal cord injury.
Journal of rehabilitation medicineTowards an understanding of disturbed sleep phenotypes after traumatic spinal cord injury.
Journal of rehabilitation medicineAdipose tissue-derived stromal cells enhance glycolytic metabolism in injured nerve cells via the FOXK1-HK2 axis for spinal cord injury repair.
Journal of translational medicineEffectiveness of transcranial magnetic stimulation on gait and spasticity in people with spinal cord injury: a systematic review and meta-analysis.
Spinal cordRestoring rapid natural bimanual typing with a neuroprosthesis after paralysis.
Nature neuroscienceAn environmental enrichment facilitates the recovery of lower urinary tract function after spinal cord injury through downmodulation of neurogenic activity in female rats.
World journal of urology[Effect of Yiyuan moxibustion on regulating ferroptosis in rats with urinary retention after spinal cord injury via the NRF2/GPX4 pathway].
Zhen ci yan jiu = Acupuncture research[Trends of disease burden on spinal cord injury in China from 1990 to 2023].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery[Rehabilitation guidelines and specifications for traumatic spinal cord injury (2025 edition)].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgeryThe Italian version of the International Standards for Neurological Classification of Spinal Cord Injury.
European journal of physical and rehabilitation medicineEffects of early photobiomodulation therapy on motor recovery in patients with incomplete acute cervical spinal cord injury: A multicenter randomized controlled trial.
Journal of orthopaedic translationThe PTBP1-EZH2-DOCK2 axis promotes M1 microglial polarization and exacerbates neuronal apoptosis following spinal cord injury.
Journal of orthopaedic translationProfibrotic macrophage-derived CXCL4 promotes pericyte-to-myofibroblast transition after spinal cord injury.
Journal of orthopaedic translationHigh-energy traumatic spondyloptosis at T8-T9 with complete spinal cord injury: a case report.
Frontiers in surgerySynergy Feedback Control Predicts Walking Across Multiple Cycles.
bioRxiv : the preprint server for biologyRewiring the Lung-CNS Axis After Spinal Cord Injury.
Journal of inflammation researchExoskeletal-Assisted Training in Veterans With Chronic Stroke: A Pilot Study.
Archives of rehabilitation research and clinical translationA retrospective Chinese study on optical-electromagnetic navigation-guided biportal endoscopic unilateral laminotomy for bilateral decompression in lumbar spinal stenosis: improving precision and efficiency.
Asian spine journalExpanding the path to spinal cord injury medicine certification: A practice-based solution.
PM & R : the journal of injury, function, and rehabilitationFunctional Goals of Individuals with Cervical Spinal Cord Injury undergoing Surgical Reconstruction for Elbow Extension and their Representation in Standard Assessments.
Archives of physical medicine and rehabilitationEffects of Acetyl-l-Carnitine on the Mitophagy in the Spinal Cord Injury Progression Through PINK/Parkin Pathway.
Journal of biochemical and molecular toxicologyDual receptor therapy with pituitrin for spinal cord injury-induced diabetes insipidus: A propensity-matched retrospective cohort study.
Chinese journal of traumatology = Zhonghua chuang shang za zhiSYK-dependent lipid handling in monocyte-derived macrophages governs functional recovery after spinal cord injury.
Brain research bulletinEmployment and productivity losses from cervical spinal cord injury: a 7-year nationwide cohort study in Taiwan, 2012-2018.
Journal of medical economicsPharmacological manipulation of the immediate effects of spinal trauma in neonatal rats reveals a crucial role for TRPV4 receptors.
The Journal of physiologyInjectable Metal-Free Carbon Dot-Integrated Hydrogel for Regulating Inflammation via Macrophage Metabolic Reprograming in Spinal Cord Injury Therapy.
ACS nanoHigh-Thoracic Spinal Cord Injury Impairs Biventricular Function and Blunts Cardiopulmonary Interactions in a Rodent Model.
Journal of neurotraumaThe Role of Phagocytic Cells in the Achilles Tendon.
International journal of molecular sciencesRetrospective Analysis of Cardiovascular Effects of FES Cycling in People with Complete and Incomplete Spinal Cord Injury.
Journal of clinical medicineRepetitive Transcranial Magnetic Stimulation for Spasticity in Stroke and Other Neuromotor Disorders: A Systematic Review of Randomized Clinical Trials.
Journal of clinical medicineIntegrated Clinical Workflow for Preoperative Planning and Resection of Giant Iliofemoral Heterotopic Ossification Using Three-Dimensional Technologies.
Journal of clinical medicineEffect of an exosuit on daily life gait performance in individuals with incomplete spinal cord injury: a randomized controlled trial.
Journal of neuroengineering and rehabilitationComparison of health outcomes between traumatic spinal cord and cauda equina injuries.
Spinal cordLactation and Breastfeeding in Women With Spinal Cord Injury: A Scoping Review.
Journal of human lactation : official journal of International Lactation Consultant AssociationGLP-1 receptor agonists as pharmacological treatment for obesity after spinal cord injury: clinical considerations.
Archives of physical medicine and rehabilitationPersistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsDisparities and institutional variation in time to surgery for traumatic cervical spinal cord injury: a multicenter cohort study.
Journal of neurosurgery. SpineImpact of acupuncture combined with ganglioside therapy on serum inflammatory cytokine levels in acute cervical spinal cord injury without fracture or dislocation.
MedicinePrevalence and risk factors of cholelithiasis in patients with spinal cord injury: A cross-sectional analysis.
PloS oneSpinal Cord Stimulation Alleviates Spinal Cord Injury-Induced Neuropathic Pain Via m5C-Dependent Regulation of TRAF2.
Neurochemical researchAcute cardio-centric haemodynamic management preserves chronic cardiovascular function in pigs with high-thoracic spinal cord injury.
The Journal of physiologyLate Venous Thromboembolism Chemoprophylaxis and Increased Risk of Deep Venous Thrombosis, Pulmonary Embolism, and Mortality in Patients with Traumatic Spinal Injury.
Journal of the American College of SurgeonsPostacute Ventilator Weaning and Discharge Outcomes in Individuals With Cervical Spinal Cord Injury: A Retrospective Analysis.
Respiratory careAn integrated analysis of spinal cord transcriptome and gut microbiome unravel age-associated host-microbiome interactions following spinal cord injury.
Frontiers in immunologyImproving muscle recruitment via multi-electrode transcutaneous spinal cord stimulation using automated selectivity-driven algorithms.
APL bioengineeringA spatiotemporally controlled MNE@PDA-Diz/GP hydrogel system: enhancing spinal cord injury repair via ROS scavenging, calcium influx inhibition, and macrophage polarization.
RSC advancesNeuroprotective effects of pregabalin in experimental spinal cord injury: An investigation of oxidative stress and antioxidant enzymes in blood and neural tissue.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTESNetwork Pharmacology Combined With Clinical Retrospective Analysis to Investigate the Potential Mechanisms and Clinical Significance of Folate in Treating Spinal Cord Injury.
Pharmacology research & perspectivesGait analysis methods in people with spinal cord injury: a systematic review.
Journal of neuroengineering and rehabilitationPredictors of transition readiness in adolescents with neurogenic lower urinary tract dysfunction.
Journal of pediatric urologyInspiratory muscle training for people with spinal cord injury: An implementation study.
Clinical rehabilitationTEAD1 Enhances Exosome Secretion and Promotes Exosome-Mediated Tissue Regeneration.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)Impact of delayed diagnosis on surgical management and neurological outcomes in elderly patients with cervical spinal cord injury without radiographic evidence of trauma: a multicenter registry study.
Spinal cordPerilesional neuromodulation replaces lost sensorimotor function in persons with spinal cord injury.
Nature biomedical engineeringAssistive Robotic Arm to Support Activities of Daily Living in Individuals With Tetraplegia: Protocol for a Real-World Convergent Parallel Mixed Methods Feasibility Study.
JMIR research protocolsQualitative insights into government financial assistance use after spinal cord injury.
Archives of physical medicine and rehabilitationStaged Brachialis to Anterior Interosseous Nerve Transfer With Graft for Recovery of Grasp in the Tetraplegic Patient: Technical Report.
Operative neurosurgery (Hagerstown, Md.)Identification and Verification of Mitochondria-Related Diagnostic Markers of Spinal Cord Injury by WGCNA and Machine Learning.
Behavioural neurologyThe effect of breathing exercises and mindset with or without cold exposure on mental and physical health in persons with a spinal cord injury-Results of a randomized controlled trial.
Clinical rehabilitationCervical spinal cord injury following near-hanging without associated cervical fracture: a case report.
Journal of spine surgery (Hong Kong)Insurance disparities are associated with worse post-rehabilitation outcomes in gunshot vs. motor vehicle accident spinal cord injury: a retrospective cohort study.
Journal of spine surgery (Hong Kong)Life after the hospital: Lived experience of people with traumatic spinal cord injury in a resource-constrained setting - a qualitative study.
The South African journal of physiotherapyMesenchymal stem cells and the central nervous system: historical perspectives and future directions.
Frontiers in molecular neuroscienceTreatment of spinal cord injury, by restoration of neuronal networks using a combination of surgery and KCL-286, an orally available retinoic acid receptor β drug.
Frontiers in surgeryMitochondrial metabolism restoration via Tramiprosate suppresses mitochondrial ROS-driven foamy macrophage senescence post spinal cord injury.
Journal of orthopaedic translationPrescription Trends and Clinical Decision-Making in Neuropathic Pain Pharmacological Treatment: Results From a Cross-Sectional Survey by the Spanish Pain Society.
European journal of pain (London, England)The Effect of a Guideline-Based Training Program on the Knowledge Level of Rehabilitation Nurses About Intermittent Catheterization: A Pretest-Posttest Study.
Rehabilitation nursing : the official journal of the Association of Rehabilitation NursesA novel cannabidiol-derived small molecule ameliorates lower urinary tract dysfunction in mice with spinal cord injury via suppressing neuroinflammation.
Life sciencesTargeted H2S Delivery System Attenuates Blood-Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)Mechanistic study of locally transplanted bone marrow mesenchymal stem cells combined with erythropoietin in acute spinal cord injury.
Neurological researchCortical Brain Activation During Robot-Assisted Gait in Humans With Acute and Chronic Spinal Cord Injury: A Functional Near-Infrared Spectroscopy Study.
The European journal of neuroscienceUnderstanding the Link Between Spirituality and Neurorehabilitation: A Narrative Review.
NeuroRehabilitationTranscutaneous spinal cord stimulation combined with robot-assisted gait training to improve mobility and balance in spinal cord injury: intramuscular electromyography as a biomarker for functional recovery.
BMC medicineMedFusion-gP-AKI: development and multicenter validation of a machine learning fusion model for early prediction of KDIGO stage 3 acute kidney injury in critically ill traumatic cervicothoracic spinal cord injury patients.
Renal failureNeuronal plasticity during motor rehabilitation training after spinal cord injury.
Communications biologyWearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury.
Spinal cordForensic and neuropathological characteristics of lethal acute blunt traumatic spinal cord injury.
Journal of forensic sciencesNeuregulin1-ErbB4 Signaling Involved in Acupuncture Promoting Myelin Regeneration in Spinal Cord Injury Rats.
Journal of visualized experiments : JoVEAn Intuitive, Bidirectional, Adaptive Functional Electrical Stimulation System for Hand Rehabilitation.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology SocietyIn-Depth Real-World Evidence: Assembling a Comprehensive Spinal Cord Injury or Disease Veteran Cohort to Advance Understanding of Neurogenic Lower Urinary Tract Dysfunction.
Neurourology and urodynamicsPre-stroke Fulfilment of WHO Recommendations for Physical Activity: A Cross-Sectional Study.
Western journal of nursing researchAccuracy and safety of navigated pedicle screw insertion in cervical spine fractures.
Frontiers in surgerySystemic Interleukin-4 Application Promotes Functional Recovery and Reprograms Neuroinflammatory and Molecular Responses after Spinal Cord Injury in Rats.
TheranosticsPANoptosis: a new perspective for targeting programmed cell death after spinal cord injury.
Frontiers in immunologyCan Transcutaneous Vagus Nerve Stimulation be Effective After Rats' Spinal Cord Injury?
CureusTraumatic Cervical Myelopathy Masked by Alcohol Intoxication and Diagnostic Anchoring.
CureusSeverity Prediction of Traumatic Cervical Spinal Cord Injury With an AI Model Based on MRI Radiomics.
JOR spine3D bioprinted multifunctional GelMA/TMP scaffold integrated with neural stem cell-derived extracellular vesicles and neural progenitor cells for spinal cord injury repair.
Journal of tissue engineeringNINJ1 monoclonal antibody alleviates neuroinflammation and promotes functional recovery after spinal cord injury by suppressing pyroptosis-mediated DAMPs release.
NeuroscienceTargeting Neuroinflammatory and Regenerative Pathways with Monoclonal Antibodies in Spinal Cord Injury: A Bibliometric Analysis.
World neurosurgeryOSBPL10 alleviates neuronal ferroptosis via lysosomal membrane repair in a PS-dependent manner after spinal cord injury.
Journal of neuroinflammationAPOE-mediated lipid transport prevents C1q-related synaptic loss after spinal cord injury via attenuating macrophage lipid stress.
Journal of neuroinflammationStudy design considerations in clinical trials testing transcutaneous stimulation for spinal cord injury.
Spinal cordEfficient generation of human dorsal spinal GABAergic progenitors for the treatment of spinal cord injury.
Experimental & molecular medicineMethyltransferase-like protein 16 suppresses spinal cord injury by regulating microglia polarization via N6-methyladenosine-modified downregulation of MCEMP1.
Journal of neuropathology and experimental neurologyPrediction of neurological prognosis of patients with acute traumatic cervical spinal cord injury using Neurite Orientation Dispersion and Density Imaging (NODDI).
Magnetic resonance imagingTime-dependent adaptations of damaged neurons and their microenvironment in the regenerating adult zebrafish spinal cord.
Science advancesUnbiased quantification of persistent postural and motor deficits following spinal cord injury in mice.
PloS oneInsights into Astrogliosis, Inflammation Processes, and Emerging Treatments by Exosome Therapy and Low-Level Laser Therapy for Spinal Cord Injury: A Systematic Review.
Journal of lasers in medical sciencesSpinal cord injury-induced overflow incontinence reshapes the activin-follistatin-inhibin axis in mouse bladder and kidney.
Frontiers in molecular biosciencesPrecision restoration of complex cervical instability and decompression for neurofibromatosis type I: a case report using patient-specific 3D-printed templates.
Frontiers in surgeryAntibiotic Resistance Identification Among the Patients with Helicobacter pylori Infection: A Cross-sectional Study from Iran.
Middle East journal of digestive diseasesReconstruction of Stage IV Pressure Ulcers Using Delayed Flaps in a Pediatric Patient With Spinal Cord Injury: A Case Report.
CureusPharmacotherapy in the acute phase of secondary spinal cord injury: an updated narrative review.
European journal of medical researchA mechanistic, imaging-based classification of complete retrograde ejaculation: insights from dynamic transrectal ultrasonography.
European journal of medical researchAngiopep-2-engineered extracellular vesicles derived from spinal cord injury-responsive brown adipose tissue for targeted neuroinflammation modulation.
Journal of nanobiotechnologyIn-hospital outcomes and temporal analysis of paralyzed patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Scientific reportsBladder management for adults with spinal cord injury in the acute hospital setting: A retrospective study.
Spinal cord series and casesStereotactic rodent-to-human approximation of the mesencephalic cuneiform nucleus to guide deep brain stimulation.
Brain stimulationSilencing Adamts2 attenuates fibroblast-mediated fibrosis and promotes axonal regeneration in an in vitro model.
Cellular signallingEngineered exosomes mediated siNox4 delivery loaded polyzwitterionic hydrogel with electrophysiologic conductivity for synergistic treatment of spinal cord injury via suppressing neuronal ferroptosis.
BiomaterialsUltra-early surgery within 12 hours is associated with improved short-term outcomes after traumatic cervical spinal cord injury: A retrospective cohort study.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research SocietyRecovery rate of functional motor independence during inpatient rehabilitation after traumatic cervical spinal cord injury predicts functional status at years 1 and 5 after surgery: A multicenter, longitudinal cohort study.
The journal of spinal cord medicineInjectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats.
Journal of materials chemistry. BRigorous reporting of case reports in spinal cord injury: A collective responsibility.
The journal of spinal cord medicineManagement of Pressure Sore at Tertiary Care Center in Western Nepal: An Observational Study.
JNMA; journal of the Nepal Medical AssociationElderly patient with a calcified upper cervical meningioma acutely worsened by head trauma.
Surgical neurology internationalNeuroprotection or Neurotoxicity? Insights from preclinical and clinical studies of methotrexate in spinal cord injury.
Surgical neurology internationalMissed T8-T9 Translational Fracture with Intact Neurology: A Case Report.
JNMA; journal of the Nepal Medical AssociationValue of Intraoperative Neuromonitoring in Spinal Tuberculosis Surgery: A Case Report of Neurological Compromise with Normal Imaging.
Asian journal of neurosurgeryHigh MAP3K6 expression in spinal cord injury tissues enhances neuronal apoptosis: insights from multi-omics data integrating WGCNA, machine learning and experimental validation.
The International journal of neuroscienceMatrix Metalloproteinase-Activatable Nanodrug Crossing Blood-Spinal Cord Barrier for On-Demand Drug Release in Spinal Cord Injury Repair.
ACS nanoFocal Estrogen Therapy in Male Rats Promotes Neuronal Survival and Reduces Denervation Atrophy After Spinal Cord Injury via Modulation of β-Catenin and NF-κB.
Neurochemical researchDual strategies for neural injury repair: Targeted modulation of reactive astrocytes and functional astrocyte transplantation.
Neural regeneration researchRole of mechanobiology in neuroregeneration.
Neural regeneration researchChallenges with Tracking Post Concussive Symptoms Using the Neurobehavioral Symptom Inventory in Active Duty Service Members with Mild Traumatic Brain Injury.
Military medicineCurrent Advancements in the Arsenal for Spinal Cord Injury Repair: Novel Drug Formulations.
International journal of nanomedicineInternational Delphi consensus on feminising genital surgery in assigned-male-at-birth individuals.
BJU internationalMotor imagery BCI enables more practical and user-friendly exoskeleton control than smartwatch for users with spinal cord injury: a preliminary study.
Journal of neuroengineering and rehabilitationPaired associative stimulation with a high-intensity cortical component and a high-frequency peripheral component in treatment of neuropathic pain after incomplete spinal cord injury - a pilot trial.
Spinal cord series and casesThe profile of persons with traumatic spinal cord injury and the associated factors of length of stay in a rehabilitation centre, in South Africa.
Spinal cordInfluence of multiple trauma on the effect of transfusion strategies in patients with traumatic brain injury: a sub-study of the HEMOTION trial.
Intensive care medicineThe efficacy of surgical management in post traumatic syringomyelia: A systematic review.
The journal of spinal cord medicineExtracellular Vesicle-Mediated Precision Delivery of Paclitaxel Activates Mitophagy to Promote Repair after Spinal Cord Injury.
ACS nanoGlycolysis-related gene signatures in spinal cord injury pathophysiology identification through integrative gene expression analysis.
Frontiers in geneticsAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Ddx20, DEAD-box helicase 20 is essential for maintaining microglial homeostasis.
- Repurposing Dexmedetomidine: Early Pharmacological Hypothermia Enhances Neuroprotection and Improves Locomotor and Bladder Functional Recovery After SCI.The Journal of neuroscience : the official journal of the Society for Neuroscience· 2026· PMID 41862205mais citado
- Central and peripheral neuroplasticity in cervical spinal cord injury following intensive upper limb motor training: a randomised controlled trial protocol.
- Exosome-Loaded Engineered circBDNF Promotes Spinal Cord Injury Repair Through the PI3K/AKT/mTOR Signaling Axis.
- Liproxstatin-1 improves functional recovery after acute spinal cord injury by inhibiting ferroptosis-induced inflammation.
- Immediate Consequences of a Spinal Cord Injury During Development: Unique Insights From Ex Vivo Models.
- Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar-Limited Repair in Adult Spinal Cord Injury.
- Duodenal perforation following right nephrectomy in a paraplegic patient with pyonephrosis: a case report and clinical insights.
- Case Report: Transverse myelitis following CAR-T cell therapy for post-transplant lymphoproliferative disorder.
- The Minimal Detectable Change for Balance and Balance Confidence After Chronic Spinal Cord Injury.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:90058(Orphanet)
- MONDO:0043797(MONDO)
- GARD:19109(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q1415275(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
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