Raras
Buscar doenças, sintomas, genes...
Tumor de plasmócitos
ORPHA:98282DOENÇA RARA

Uma multiplicação descontrolada de plasmócitos idênticos, que são células que produzem imunoglobulinas (também chamadas de anticorpos). Essa categoria inclui o mieloma múltiplo, a leucemia de plasmócitos, o plasmocitoma, a doença de deposição de imunoglobulina monoclonal e a gamopatia monoclonal de significado incerto.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

Uma multiplicação descontrolada de plasmócitos idênticos, que são células que produzem imunoglobulinas (também chamadas de anticorpos). Essa categoria inclui o mieloma múltiplo, a leucemia de plasmócitos, o plasmocitoma, a doença de deposição de imunoglobulina monoclonal e a gamopatia monoclonal de significado incerto.

Pesquisas ativas
22 ensaios
420 total registrados no ClinicalTrials.gov
Publicações científicas
336 artigos
Último publicado: 2026 Apr 17
🏥
SUS: Cobertura mínimaScore: 5%
Triagem neonatal (Fase 5)
Você se identifica com essa condição?
O Raras está aqui pra te apoiar — com ou sem diagnóstico

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🦴
Ossos e articulações
9 sintomas
🩸
Sangue
7 sintomas
🫃
Digestivo
6 sintomas
🫘
Rins
5 sintomas
🧬
Pele e cabelo
2 sintomas
📏
Crescimento
2 sintomas

+ 24 sintomas em outras categorias

Características mais comuns

Anormalidade do intestino delgado
Erupção cutânea
Morfologia anormal do palato
Anemia hemolítica autoimune
Atraso de crescimento
Dor abdominal
62sintomas
Sem dados (62)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 62 características clínicas mais associadas, ordenadas por frequência.

Anormalidade do intestino delgadoAbnormality of the small intestine
Erupção cutâneaSkin rash
Morfologia anormal do palatoAbnormal palate morphology
Anemia hemolítica autoimuneAutoimmune hemolytic anemia
Atraso de crescimentoGrowth delay

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico336PubMed
Últimos 10 anos110publicações
Pico202418 papers
Linha do tempo
2026Hoje · 2026🧪 1975Primeiro ensaio clínico📈 2024Ano de pico
Publicações por ano (últimos 10 anos)

Triagem neonatal (Teste do Pezinho)

👶
Teste: qPCR para deleção de SMN1 em sangue seco
Fase 5 do PNTNpending
Incidência no Brasil: 1:10.000

A triagem neonatal permite diagnóstico precoce e início imediato do tratamento.

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

Genes associados

2 genes identificados com associação a esta condição.

CCND1G1/S-specific cyclin-D1Candidate gene tested inRestrito
FUNÇÃO

Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition (PubMed:1827756, PubMed:1833066, PubMed:19412162, PubMed:33854235, PubMed:8114739, PubMed:8302605). Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression

LOCALIZAÇÃO

NucleusCytoplasmNucleus membrane

VIAS BIOLÓGICAS (9)
Cyclin D associated events in G1PTK6 Regulates Cell CycleSCF(Skp2)-mediated degradation of p27/p21SPOP-mediated proteasomal degradation of PD-L1(CD274)Transcriptional Regulation by VENTX
OUTRAS DOENÇAS (5)
B-cell chronic lymphocytic leukemiaplasma cell myelomavon Hippel-Lindau diseasemantle cell lymphoma
HGNC:1582UniProt:P24385
LIG4DNA ligase 4Candidate gene tested inTolerante
FUNÇÃO

DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination (PubMed:12517771, PubMed:17290226, PubMed:23523427, PubMed:29980672, PubMed:33586762, PubMed:8798671, PubMed:9242410, PubMed:9809069). Catalyzes the NHEJ ligation step of the broken DNA during DSB repair by resealing the DNA breaks after the gap filling is completed (PubMed:12517771, PubMed:17290226, PubMed:9242410, PubMed:9809069). Joins single-strand breaks in a d

LOCALIZAÇÃO

Nucleus

VIAS BIOLÓGICAS (2)
Nonhomologous End-Joining (NHEJ)2-LTR circle formation
MECANISMO DE DOENÇA

LIG4 syndrome

Characterized by immunodeficiency and developmental and growth delay. Patients display unusual facial features, microcephaly, growth and/or developmental delay, pancytopenia, and various skin abnormalities.

EXPRESSÃO TECIDUAL(Ubíquo)
Pituitária
17.9 TPM
Cérebro - Hemisfério cerebelar
17.6 TPM
Cerebelo
16.5 TPM
Linfócitos
15.0 TPM
Testículo
13.6 TPM
OUTRAS DOENÇAS (4)
DNA ligase IV deficiencyDubowitz syndromeOmenn syndromeplasma cell myeloma
HGNC:6601UniProt:P49917

Variantes genéticas (ClinVar)

274 variantes patogênicas registradas no ClinVar.

🧬 CCND1: GRCh37/hg19 11q12.2-13.5(chr11:59923608-76272324)x3 ()
🧬 CCND1: NC_000011.9:g.(?_64973914)_(70052579_?)dup ()
🧬 CCND1: GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 ()
🧬 CCND1: GRCh37/hg19 11q13.3-13.4(chr11:69214835-70821137)x1 ()
🧬 CCND1: Single allele ()
Ver todas no ClinVar

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 23
1Fase 17
·Pré-clínico10
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Tumor de plasmócitos

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

13 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

420 ensaios clínicos encontrados, 22 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
🧪 Está conduzindo uma pesquisa?
Divulgue para pacientes e familiares que acompanham esta doença.
Divulgar pesquisa →

Publicações mais relevantes

Timeline de publicações
113 papers (10 anos)
#1

Pneumocystis jirovecii infection in autologous hematopoietic stem cell transplantation.

Leukemia & lymphoma2026 Mar

Pneumocystis jirovecii pneumonia (PJP) after autologous stem cell transplantation (ASCT) remains insufficiently characterized. We retrospectively analyzed 304 ASCT recipients (2005-2024) at a single center (B-cell lymphoma n = 138; plasma cell tumor n = 126). Fourteen patients (4.6%) developed PJP at a median of 143 days (86-286) post-ASCT; none were on prophylaxis at diagnosis. The 1-year cumulative incidence was 5.2% overall, and varied by disease: 24% in follicular lymphoma (FL), 5.9% in other B-cell lymphomas, 1.9% in plasma cell tumor, and 0% in T-cell lymphomas. Prior rituximab exposure (HR 6.75; 95% CI 1.50-30.2) and FL diagnosis (HR 7.26; 95% CI 2.51-20.9) were associated with higher risk; age, purine analogs, lymphocyte count, globulin/IgG, and conditioning were not. No death was directly attributable to PJP. These data suggest, diagnosis-dependent risk after ASCT; prophylaxis may be considered for rituximab-treated patients, especially FL, while the optimal duration warrants further study.

#2

Conjunctival plasmacytoma: A case study.

Archivos de la Sociedad Espanola de Oftalmologia2026 Feb

Plasmacytomas are localized collections of monoclonal plasma cells. This is a 48-year-old female patient of mixed race, with no significant medical history, with a soft, painless tumor adhered to the sclera, in the bulbar conjunctiva and inferior temporal fornix. The method used was the presentation of a clinical case. The tumor was excised with pathological analysis and immunohistochemical study confirming the diagnosis of conjunctival plasmacytoma. Postoperative follow-up was uneventful. Extraosseous plasma cell tumors located in the eye are rare and difficult to diagnose because they present a wide range of clinical differentiation.

#3

Intramuscular enhancing masses: Late relapse of multiple myeloma mimicking hematoma in trauma setting.

Radiology case reports2026 Feb

Extramedullary disease (EMD) is an uncommon and aggressive form of multiple myeloma, especially when localized to intramuscular locations. We present a case of a 45-year-old man with a history of IgG multiple myeloma (MM), who underwent allogeneic bone marrow transplantation and had been in clinical remission for more than a decade. He presented acutely after trauma with computed tomography (CT) revealed several enhancing masses in bilateral psoas, right obturator internus, right adductors and left sartorius muscles, which were initially misinterpreted as intramuscular hematomas. These masses remained stable on follow-up imaging, raising concern for underlying undiagnosed soft tissue tumors. Biopsy of one of the masses demonstrated a plasma cell tumor, and further evaluation confirmed relapse of multiple myeloma. Additionally, the largest mass in the left psoas exhibited peripheral calcification-an unusual imaging characteristic of extra ossous myeloma. Despite imaging following trauma, the presence of intramuscular masses in patients with history of MM should raise a high degree of clinical suspicion for EMD. Recognition of this diagnostic pitfall can help avoid delay diagnosis and inappropriate management.

#4

Ethmoid tumors in free-ranging white-tailed deer (Odocoileus virginianus).

Veterinary pathology2026 Jan

This report describes a series of ethmoid tumors in 6, free-ranging white-tailed deer (Odocoileus virginianus; WTD) in southwest to central Texas, which included 4 plasma cell tumors, 1 adenosquamous carcinoma, and 1 adenocarcinoma. The plasma cell tumors had a distinctive presentation with unilateral to bilateral facial masses located rostromedial to the eyes that were smooth and fluctuant. Upon dissection, these preorbital facial masses consisted of multiloculated, mucus-filled, cystic pockets with 2 having partial extension of the ethmoid tumors into the external facial masses. The 2 carcinomas were larger, unilateral, solid facial masses. All tumors caused extensive destruction of the ethmoid region with the carcinomas being paler, firmer, and more invasive into surrounding areas compared with the plasma cell tumors. Ancillary testing did not reveal an underlying infectious cause, although these reports of multiple WTD across a localized region suggest a possible infectious, environmental, or other shared stimulus.

#5

Case Report: Ultrasonographic and computed tomographic features of presumed gastric plasmacytoma (plasma cell tumor) with ulceration in two dogs.

Frontiers in veterinary science2025

Gastric plasmacytoma is rare in dogs, with only four previous reports providing limited descriptions of abdominal ultrasound (AUS) and computed tomography (CT) findings. This study presents the AUS and CT imaging features of two histopathologically suspected gastric plasmacytomas. Combining the four previous and two new cases, these tumors predominantly occurred in the greater curvature and pyloric antrum as solitary round masses connected to the submucosal or transmural layers. Pre- and post-contrast tissue attenuation (Hounsfield unit; HU) differences exceeded 40, with variable AUS echogenicity and echotexture. Imaging features may resemble those of spindle cell tumors, requiring histological and immunohistochemical examinations for definitive diagnosis.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC100 artigos no totalmostrando 109

2026

Pneumocystis jirovecii infection in autologous hematopoietic stem cell transplantation.

Leukemia & lymphoma
2026

Conjunctival plasmacytoma: A case study.

Archivos de la Sociedad Espanola de Oftalmologia
2026

Intramuscular enhancing masses: Late relapse of multiple myeloma mimicking hematoma in trauma setting.

Radiology case reports
2025

Prognostic value assessment and in vitro validation of mitochondria-ferroptosis-related genes in multiple myeloma.

Scientific reports
2025

Cyanidin-3-O-glucoside-mediated reduction of regulatory T cells: a therapeutic strategy for multiple myeloma.

BMC immunology
2025

[Multiple Myeloma Without Monoclonal Component: Nonsecretory and Non-Producing. Case Report and Review].

Revista medica de Chile
2025

Case Report: Ultrasonographic and computed tomographic features of presumed gastric plasmacytoma (plasma cell tumor) with ulceration in two dogs.

Frontiers in veterinary science
2025

Unexplained cardiac hypertrophy as a clue to plasma cell tumour: a case study.

American journal of translational research
2026

Ethmoid tumors in free-ranging white-tailed deer (Odocoileus virginianus).

Veterinary pathology
2025

Solitary Plasmacytomas: Current Status in 2025.

Hematology reports
2025

Case report and comprehensive literature review: A rare instance of solitary extramedullary plasmacytoma in the trachea.

Respiratory medicine case reports
2025

SPAG6 Promotes Multiple Myeloma Through Activation of the MAPK/ERK Signaling Pathway.

Frontiers in pharmacology
2025

First-line anti-BCMA CAR-T cell therapy in a fragile patient with biclonal gammopathy and giant plasma cell tumor multiple myeloma with multiple comorbidities: a case report.

Frontiers in immunology
2025

Review of tracheal neoplasia in dogs and cats (1961-2024).

Veterinary pathology
2025

Canine laryngotracheal plasma cell tumors: Ten cases and literature review.

Veterinary pathology
2025

[Risk stratified thromboprophylaxis and management of thrombotic events in plasma cell neoplasms].

Zhonghua yi xue za zhi
2025

Plasma Cell-Rich Lymphoid Neoplasm in an Endocervical Polyp of the Uterine Cervix in a Perimenopausal 52-Year-Old Woman.

HCA healthcare journal of medicine
2025

FIRST REPORT OF TUMORS IN GARDEN DORMICE (ELIOMYS QUERCINUS).

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians
2024

[Analysis and reflections on the current status of diagnosis and treatment of marginal zone lymphoma].

Zhonghua yi xue za zhi
2024

A Rare Case of Solitary Endobronchial Plasmacytoma Presented With Complete Airway Obstruction: A Case Report.

Journal of investigative medicine high impact case reports
2024

2-Dimensional Operative Video for Staged Treatment of a Giant Plasma Cell Tumor: Principles for Neurosurgical Oncology During a Wartime Environment in Ukraine.

Operative neurosurgery (Hagerstown, Md.)
2024

Transendoscopic laser ablation of an esophageal plasma cell tumor in a cat.

JFMS open reports
2024

Acquired Bortezomib Resistance in Multiple Myeloma: From Mechanisms to Strategy.

Current treatment options in oncology
2024

Mandibular salivary gland plasma cell tumor in a dog.

Topics in companion animal medicine
2024

Changes in the immune microenvironment during plasma cell tumor development in the IL6Myc mouse model of human multiple myeloma.

Experimental cell research
2024

A "gullwing sign" on magnetic resonance imaging of extradural spinal tumors in dogs and cats allows prioritization of round cell neoplasia.

Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
2024

Prognostic factors in Chinese patients with immunoglobulin light chain amyloidosis: a scoping review and meta-analysis.

Annals of medicine
2024

Interference with PLA2G16 promotes cell cycle arrest and apoptosis and inhibits the reprogramming of glucose metabolism in multiple myeloma cells by modulating the Hippo/YAP signaling pathway.

Anti-cancer drugs
2024

Refining the relationship between gut microbiota and common hematologic malignancies: insights from a bidirectional Mendelian randomization study.

Frontiers in cellular and infection microbiology
2024

Cutaneous plasmacytoma with Mott cell differentiation in a dog.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2024

Successful Treatment of Refractory Orbital Plasmacytoma with Chimeric Antigen Receptor T Cell Therapy: A Case Report and Review of the Literature.

Ophthalmic plastic and reconstructive surgery
2024

Solitary Extramedullary Plasmacytoma of the Left Lower Eyelid: A Case Report and Review of Literature.

Cureus
2024

Solitary ovarian plasmacytoma: About a rare entity of extramedullary plasma cell tumor.

International journal of surgery case reports
2023

Outcomes in dogs undergoing surgical stabilization and non-stereotactic radiation therapy for axial and appendicular bone tumors.

Frontiers in veterinary science
2023

Renal Riddles Unveiled: Decoding Homogeneous Kidney Enlargement in Multiple Myeloma.

Cureus
2023

Case report: Corpectomy and iliac crest bone autograft as treatment for a vertebral plasma cell tumor in a dachshund dog.

Frontiers in veterinary science
2024

Solitary plasmacytoma of mandible: A case report.

Radiology case reports
2023

Myocardial plasma cell tumor with intratumoral amyloidosis in a dog.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology
2024

Respiratory Distress Caused by Neoplastic Upper Respiratory Tract Obstructions in 2 Pet Rats (Rattus norvegicus domestica).

Topics in companion animal medicine
2023

Drug Expenditure, Price, and Utilization in US Medicaid: A Trend Analysis for New Multiple Myeloma Medications from 2016 to 2022.

Healthcare (Basel, Switzerland)
2023

Soft Tissue Mass Extramedullary Plasmacytoma Following Radiation Therapy for Solitary Bone Plasmacytoma.

Cureus
2023

Clinical and Laboratory Characteristics of IgM Primary Plasma Cell Leukemia.

Clinical laboratory
2024

Zinc Oxide Nanoparticles Trigger Autophagy in the Human Multiple Myeloma Cell Line RPMI8226: an In Vitro Study.

Biological trace element research
2023

A case report of POEMS syndrome with lower limb numbness and weakness.

Asian journal of surgery
2023

Solitary Extramedullary Plasmacytoma of the Head and Neck: A Report of Three Cases Treated With Curative Radiotherapy and a Review of the Dose-Control Relationship.

Cureus
2023

Solitary Plasmacytoma in the Calcaneus.

Cureus
2023

A Patient with Synchronous Gallbladder and Bone Plasmacytoma.

Diagnostics (Basel, Switzerland)
2023

[Recent Research Progress of Extramedullary Plasmacytoma --Review].

Zhongguo shi yan xue ye xue za zhi
2023

Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma.

ACG case reports journal
2023

Polyneuropathy organomegaly endocrinopathy M-protein and skin changes syndrome with ascites as an early-stage manifestation: A case report.

World journal of clinical cases
2023

Diagnosis and management of extramedullary plasmacytoma in nasal cavity: Clinical experience and literature review.

Medicine
2022

Multiple Myeloma With Retroperitoneal Extramedullary Plasmacytoma Causing Renal Failure and Obstructive Shock From Inferior Vena Cava Compression: A Case Report.

Cureus
2022

Conjunctival Extramedullary Plasmacytoma in Dogs and a Cat: Clinical Characteristics and Histopathological Findings.

Animals : an open access journal from MDPI
2022

Synergistically Anti-Multiple Myeloma Effects: Flavonoid, Non-Flavonoid Polyphenols, and Bortezomib.

Biomolecules
2022

Spheno-Orbital Plasmacytoma as an Initial Presentation of Multiple Myeloma.

Brain tumor research and treatment
2022

Cholangioscopic diagnosis of hemobilia: an unusual case of left hepatic portal hypertension by plasma cell tumor.

VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy
2022

Spatial Proteomics Reveals Differences in the Cellular Architecture of Antibody-Producing CHO and Plasma Cell-Derived Cells.

Molecular & cellular proteomics : MCP
2022

Suprasellar Plasmacytoma Leading to the Diagnosis of Multiple Myeloma.

Cureus
2022

[Extramedullary plasmacytoma of the larynx:a case report].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
2022

A Rare Case of Hormone-Induced Plasma Cell Granuloma of the Gingiva.

Cureus
2022

Urinary bladder wall mass with neoplastic lymphoid cells in the urine: Diagnosis of an IgG secretory B-cell lymphoma with Bence-Jones proteinuria in a dog.

Veterinary clinical pathology
2022

Atypical multiple myeloma in 3 young dogs.

Veterinary pathology
2022

[Primary extramedullary plasma cell tumor of the right kidney: report of a case].

Zhonghua bing li xue za zhi = Chinese journal of pathology
2022

IgG4-Related Kidney Disease Associated With End-Stage Kidney Disease, Renal Pseudotumor, and Renal Vein Thrombosis.

Cureus
2022

Tim-3 Blockade Elicits Potent Anti-Multiple Myeloma Immunity of Natural Killer Cells.

Frontiers in oncology
2021

Are the Derived Indexes of Peripheral Whole Blood Cell Counts (NLR, PLR, LMR/MLR) Clinically Significant Prognostic Biomarkers in Multiple Myeloma? A Systematic Review And Meta-Analysis.

Frontiers in oncology
2021

Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report.

Medicine
2021

Coexistence of cervical extramedullary plasmacytoma and squamous cell carcinoma: A case report.

World journal of clinical cases
2021

Impact of hypoxia on the pathogenesis and therapy resistance in multiple myeloma.

Cancer science
2021

Case report of peritoneal carcinomatosis of plasma cell origin in a patient with newly diagnosed HIV: A terminal event.

AIDS research and therapy
2021

Spinal cord compression due to a solitary, bulky plasmacytoma of posterior mediastinum.

Radiology case reports
2021

Lymphoma in Psittacine Birds: A Histological and Immunohistochemical Assessment.

Veterinary pathology
2021

A rare case of primary solitary endobronchial plasmacytoma.

Thoracic cancer
2020

Magnetic Resonance Imaging Features of Extradural Spinal Neoplasia in 60 Dogs and Seven Cats.

Frontiers in veterinary science
2020

Clinical Analysis of Castleman's Disease of the Lacrimal Gland.

Journal of ophthalmology
2020

Super-Enhancer Associated Five-Gene Risk Score Model Predicts Overall Survival in Multiple Myeloma Patients.

Frontiers in cell and developmental biology
2020

Mouse tumor susceptibility genes identify drug combinations for multiple myeloma.

Journal of cancer metastasis and treatment
2020

Primary extramedullary plasmacytoma of the eyelid conjunctiva - A case report and review of the literature.

Annals of medicine and surgery (2012)
2020

Quantification by Ultrafiltration and Immunofixation Electrophoresis Testing for Monoclonal Serum Free Light Chains.

Laboratory medicine
2021

Long non-coding RNA PVT1 regulates the migration of hepatocellular carcinoma HepG2 cells via miR-3619-5p/MKL1 axis.

Bosnian journal of basic medical sciences
2020

Clinical Features of Head and Neck Solitary Extramedullary Plasmacytoma in Taiwan.

In vivo (Athens, Greece)
2019

Plasma cell leukemia with plasmablastic morphology in a dog.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2019

Primary plasmablastic plasmacytoma in the stomach of an immunocompetent adult: A case report.

Medicine
2018

Prediction and prognostic significance of BCAR3 expression in patients with multiple myeloma.

Journal of translational medicine
2018

Total En Bloc Spondylectomy for Lumbar Spinal Tumors by Paraspinal Approach.

World neurosurgery
2018

Tonsillar plasmacytoma in a dog.

The Canadian veterinary journal = La revue veterinaire canadienne
2018

Solitary plasmacytoma of the jaws: therapeutical considerations and prognosis based on a case reports systematic survey.

Brazilian journal of otorhinolaryngology
2018

A Case of Concurrent Gastric and Pancreatic Plasmacytomas in a Patient With Multiple Myeloma: An Extremely Rare Entity.

Journal of investigative medicine high impact case reports
2018

Old and Young Actors Playing Novel Roles in the Drama of Multiple Myeloma Bone Marrow Microenvironment Dependent Drug Resistance.

International journal of molecular sciences
2018

Autologous tumor cells/bacillus Calmette-Guérin/formalin-based novel breast cancer vaccine induces an immune antitumor response.

Oncotarget
2018

Targeting MYC in multiple myeloma.

Leukemia
2018

Immunohistochemical Labeling of Multiple Myeloma Oncogene 1/Interferon Regulatory Factor 4 (MUM1/IRF-4) in Canine Cutaneous Histiocytoma.

Veterinary pathology
2018

Anaplastic plasmacytoma: a rare tumor presenting as a pathological fracture in a younger adult.

Skeletal radiology
2018

Intravascular neoplastic cells in canine cutaneous plasmacytomas.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
2017

Waldenström's macroglobulinemia: Two malignant clones in a monoclonal disease? Molecular background and clinical reflection.

European journal of haematology
2017

Current treatment options of T cell-associated immunotherapy in multiple myeloma.

Clinical and experimental medicine
2017

EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions.

Oncotarget
2016

Extramedullary Plasmacytoma Mimicking Pancreatic Cancer: An Unusual Presentation.

Case reports in oncological medicine
2017

Proceedings of the 2016 National Toxicology Program Satellite Symposium.

Toxicologic pathology
2016

Cytology of plasma cell rich effusion in cases of plasma cell neoplasm.

Journal of cytology
2016

Revisiting IL-6 antagonism in multiple myeloma.

Critical reviews in oncology/hematology
2015

Plasmacytoma to the Axis Mimicking Metastatic Paraganglioma: Circumferential Reconstruction via Posterior Approach.

Korean Journal of Spine
2015

Resident Rounds: Part III--Case Report: Metastatic Multiple Myeloma.

Journal of drugs in dermatology : JDD
2015

Non-secreting multiple myeloma switches to IgD of lamda type: a case report and review of literature.

International journal of clinical and experimental medicine
2016

Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.

Oncotarget
2015

Bone formation following lenalidomide-dexamethasone combination therapy in cases of multiple myeloma refractory to high-dose chemotherapy with bortezomib and autologous peripheral blood stem cell transplantation: report of a case and review of the literature.

International journal of clinical and experimental pathology
2015

Serous macular detachment, yellow macular deposits, and prominent middle limiting membrane in multiple myeloma.

Therapeutics and clinical risk management
2015

Osseous plasma cell neoplasm of the mandible for initial diagnosis of multiple myeloma: case report and literature review.

Journal of maxillofacial and oral surgery
2015

The tumor microenvironment shapes hallmarks of mature B-cell malignancies.

Oncogene

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

Ainda não temos associações cadastradas para Tumor de plasmócitos.

É de uma associação que acompanha esta doença? Fale com a gente →

Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

Ainda não existe comunidade no Raras para Tumor de plasmócitos

Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.

Tire suas dúvidas

Perguntas, dicas e experiências compartilhadas aqui na página

Participe da discussão

Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.

Fazer login

Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Pneumocystis jirovecii infection in autologous hematopoietic stem cell transplantation.
    Leukemia & lymphoma· 2026· PMID 41575237mais citado
  2. Conjunctival plasmacytoma: A case study.
    Archivos de la Sociedad Espanola de Oftalmologia· 2026· PMID 41461288mais citado
  3. Intramuscular enhancing masses: Late relapse of multiple myeloma mimicking hematoma in trauma setting.
    Radiology case reports· 2026· PMID 41377614mais citado
  4. Ethmoid tumors in free-ranging white-tailed deer (Odocoileus virginianus).
    Veterinary pathology· 2026· PMID 40767308mais citado
  5. Case Report: Ultrasonographic and computed tomographic features of presumed gastric plasmacytoma (plasma cell tumor) with ulceration in two dogs.
    Frontiers in veterinary science· 2025· PMID 40874204mais citado
  6. EXPRESS: Feline tarsal tumors: histologic spectrum, risk factors, and prognostic insights.
    J Feline Med Surg· 2026· PMID 41994862recente
  7. Craniofacial extramedullary plasmacytoma with hard palate and bilateral cervical lymph node involvement: a diagnostic challenge and literature review.
    BMC Oral Health· 2026· PMID 41923031recente
  8. Primary extramedullary plasmacytoma of the kidney: a case report and literature review.
    Front Oncol· 2026· PMID 41883968recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:98282(Orphanet)
  2. MONDO:0004959(MONDO)
  3. GARD:19440(GARD (NIH))
  4. Variantes catalogadas(ClinVar)
  5. Busca completa no PubMed(PubMed)
  6. Q18557283(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Tumor de plasmócitos
Compêndio · Raras BR

Tumor de plasmócitos

ORPHA:98282 · MONDO:0004959
🇧🇷 Brasil SUS
Triagem
qPCR para deleção de SMN1 em sangue seco
PNTN
Fase 5
Incidência BR
1:10.000
Geral
Ensaios
22 ativos
MedGen
UMLS
C1136084
EuropePMC
Wikidata
Papers 10a
DiscussaoAtiva

Nenhuma novidade ainda. O agente esta monitorando.

0membros
0novidades