A forma mais grave de alopecia areata, uma doença inflamatória do folículo piloso, caracterizada pela perda completa de cabelo do couro cabeludo e de todas as áreas do corpo com cabelo.
Introdução
O que você precisa saber de cara
A forma mais grave de alopecia areata, uma doença inflamatória do folículo piloso, caracterizada pela perda completa de cabelo do couro cabeludo e de todas as áreas do corpo com cabelo.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 4 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 17 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
1 gene identificado com associação a esta condição. Padrão de herança: Autosomal recessive, Multigenic/multifactorial.
Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle
Nucleus
Alopecia universalis congenita
A rare disorder characterized by loss of hair from the entire body. No hair are present in hair follicles on skin biopsy.
Variantes genéticas (ClinVar)
135 variantes patogênicas registradas no ClinVar.
Classificação de variantes (ClinVar)
Distribuição de 175 variantes classificadas pelo ClinVar.
Vias biológicas (Reactome)
10 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Alopecia universalis
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
🟢 Recrutando agora
3 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.
Outros ensaios clínicos
32 ensaios clínicos encontrados, 5 ativos.
Publicações mais relevantes
Stem cell-based therapies for alopecia areata: a narrative review.
Alopecia Areata (AA) is a chronic inflammatory disorder characterized by non-scarring, patchy hair loss that may progress to the entire scalp (alopecia totalis) or body (alopecia universalis), significantly impairing patients' quality of life and psychological health. Although the exact pathogenesis of AA remains unclear, current evidence suggests that the breakdown of hair follicle immune privilege (IP) and subsequent autoimmune-mediated follicular attack play a pivotal role. Conventional therapeutic modalities, including corticosteroid and Janus kinase (JAK) inhibitors, are often limited by suboptimal efficacy in severe cases and high relapse rates following treatment cessation. In recent years, stem cell-based therapy has emerged as a novel treatment for AA, showing therapeutic potential through multiple mechanisms. Preliminary clinical trials have indicated significant efficacy in promoting hair regrowth among AA patients. However, comprehensive evaluation of long-term safety and therapeutic efficacy remains imperative. This review article aims to give a comprehensive overview of the recent advances in stem cell-based therapies for AA and explore their underlying mechanisms and clinical application prospects, hoping to provide a framework and reference for future research and clinical practice.
Case Report: Vitiligo and Alopecia Universalis Following Rituximab Therapy in a Patient with Myasthenia Gravis.
Rituximab, an anti-CD20 monoclonal antibody, is being used more frequently to treat refractory autoimmune disorders such as myasthenia gravis. While it is usually well tolerated, rare cases of paradoxical immune-mediated skin reactions have been rarely reported. However, the concurrent development of vitiligo and alopecia universalis following rituximab therapy has not been previously described. We report a rare case of simultaneous vitiligo and alopecia universalis developing during long-term treatment with rituximab in a patient with myasthenia gravis and discuss the clinical course and treatment response. This case report describes a 30-year-old woman with myasthenia gravis who developed vitiligo followed by alopecia universalis during a long term of Rituximab therapy. Cutaneous findings included well-demarcated depigmented patches on the trunks and bilateral arms and diffuse non-scarring alopecia affecting the scalp, eyebrows, eyelashes, and body hair, consistent with 100% score of Severity of Alopecia tool (SALT) indicating Alopecia universalis. Rituximab was discontinued due to a possible drug-reaction. Treatment with oral Baricitinib was initiated to target both vitiligo and alopecia universalis. Within three months, there was significant scalp hair regrowth and re-pigmentation of vitiligo patches with minimal adverse effects. This case highlights a unique temporal association of rituximab therapy and the simultaneous onset of vitiligo and alopecia universalis. Although the relationship between the drug and the onset of the skin diseases cannot be established, it is important to be aware of the possibility of immune-related skin adverse effects during rituximab therapy. Early intervention and the use of Janus kinase inhibitors, such as baricitinib, may lead to good clinical outcomes.
From Bald to Bold: Reversal of Alopecia Totalis in an Adolescent Using Dupilumab Monotherapy.
Alopecia areata (AA) is an autoimmune condition marked by non-scarring, patchy hair loss of the scalp which progresses in <10% of cases to alopecia totalis (AT), which is marked by complete hair loss from the scalp, eyebrows, and eyelashes. AA is prevalent in pediatric patients and is associated with atopic dermatitis (AD). The interleukin (IL)-4 and IL-13 antagonist dupilumab is approved for use in both pediatric and adult patients with AD and asthma. However, in some cases, dupilumab has shown promising results in regrowing hair in patients with concurrent AA. We report a 13-year-old male patient with a past medical history of AD and food atopy, who presented with AA to the scalp. The patient's hormonal lab work-up was within normal limits, and he was treated and failed typical therapies for AA. Within nine months of treatment, the hair loss progressed to AT of the scalp and eyebrows. Dupilumab was then initiated as monotherapy for the patient's AD and AT, leading to regrowth of hair on the scalp and eyebrows within several months and sustained complete hair regeneration after 17 months post dupilumab initiation. This case demonstrates the potential use of dupilumab, which has a well-established safety profile, for pediatric patients with AA and its ability to initiate and sustain hair growth for the long term. Dermatologists may consider dupilumab for patients with AA and comorbid AD that have failed a variety of treatments from several drug classes.  .
Psoriasis Course in Patients with Alopecia Areata Undergoing Baricitinib Therapy.
Background/Objectives: Alopecia areata (AA) and psoriasis are immune-mediated diseases that can coexist, suggesting shared pathogenic mechanisms. While Janus kinase inhibitors (JAKi) are approved for AA treatment, their role in managing concomitant psoriasis and psoriatic arthritis (PsA) remains unclear. This study evaluates the efficacy and safety of baricitinib in patients with severe AA and coexisting psoriasis and/or PsA. Materials and Methods: A retrospective case series of five patients (mean age 53.2 years) with severe AA (SALT > 80) or alopecia universalis (AU) and concomitant psoriasis (n = 2) and/or PsA (n = 3) was conducted in the Dermatology Unit of Policlinico of Tor Vergata, Catholic University of the Sacred Heart and La Sapienza University of Rome, Italy. Patients received baricitinib 4 mg/day and were assessed at weeks 4, 24, and 52 using SALT, PASI, and pVAS scores. Results: At week 52, one patient achieved complete AA remission, while two improved to SALT < 20 (mean SALT 83 to 8.75). Psoriasis remained stable (mean PASI 1.4 to 0.5). However, one PsA patient worsened (pVAS 9) and discontinued the treatment. Conclusions: Baricitinib was effective for AA, with potential benefits for psoriasis, but it may not be optimal for PsA. Further studies are needed to define its role in multiple immune diseases.
Clinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications.
Ophiasis is an uncommon, clinical heterogeneous, and therapeutically challenging presentation of alopecia areata (AA). Evidence guiding meaningful subtyping and its implications for management remains limited. To characterize the clinical, trichoscopic, and histopathologic features of ophiasis and evaluate a novel subtype classification for prognostic and management relevance. A retrospective study of 150 patients with ophiasis was performed. Clinical, trichoscopic, and histopathologic data were collected and compared with patchy AA, acute diffuse and total alopecia, and alopecia universalis/alopecia totalis cohorts. A novel three-subtype classification of ophiasis based on scalp involvement patterns was proposed and evaluated its prognostic value. Ophiasis showed a female predominance, prolonged disease duration, and lower activity and regrowth rates than other AA subtypes. Trichoscopy demonstrated significant vellus hair involvement, abundant yellow dots, and minimal activity signs, while histopathology revealed minimal inflammation and increased telogen follicles, supporting chronicity. The 3 subtypes-typical ophiasis, ophiasis with patchy AA, and diffuse ophiasis-exhibited markedly different prognoses. Ophiasis with patchy AA showed comparatively favorable regrowth. Subtype classification independently predicted treatment response. Sample size, retrospective design. Ophiasis is chronic and refractory. Our proposed classification system can accurately identify patients with poorer prognosis, guiding early intervention and stratified treatment.
Publicações recentes
Case Report: Vitiligo and Alopecia Universalis Following Rituximab Therapy in a Patient with Myasthenia Gravis.
Regrowth of Eyebrows in a Previous Steroid Non-Responder With Alopecia Universalis After Ritlecitinib Treatment.
🥉 Relato de casoPsoriasis Course in Patients with Alopecia Areata Undergoing Baricitinib Therapy.
Clinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications.
📖 RevisãoStem cell-based therapies for alopecia areata: a narrative review.
🥉 Relato de caso📚 EuropePMC281 artigos no totalmostrando 198
Case Report: Vitiligo and Alopecia Universalis Following Rituximab Therapy in a Patient with Myasthenia Gravis.
Clinical, cosmetic and investigational dermatologyFrom Bald to Bold: Reversal of Alopecia Totalis in an Adolescent Using Dupilumab Monotherapy.
Journal of drugs in dermatology : JDDRegrowth of Eyebrows in a Previous Steroid Non-Responder With Alopecia Universalis After Ritlecitinib Treatment.
Journal of drugs in dermatology : JDDPsoriasis Course in Patients with Alopecia Areata Undergoing Baricitinib Therapy.
Clinics and practiceClinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications.
Journal of the American Academy of DermatologyStem cell-based therapies for alopecia areata: a narrative review.
Stem cell research & therapyCase Report: Successful treatment of pediatric alopecia universalis with ritlecitinib after failure of baricitinib.
Frontiers in medicineErythroderma, Alopecia, Anhidrosis, and Vitiligo as Complications of a Red Ink Tattoo-A Case Report.
Clinics and practiceRemission of Alopecia Areata Post-colectomy in a Patient with Crohn's Disease.
The Journal of clinical and aesthetic dermatologyImmune Cell-Targeting Biologics for Alopecia Areata: A New Paradigm in Precision Medicine.
Skin appendage disorders[Efficiency and safety of JAK inhibitors for alopecia totalis and alopecia universalis].
Zhonghua yi xue za zhi[Efficacy and safety of baricitinib treatment in alopecia areata: a retrospective analysis].
Orvosi hetilapRitlecitinib: Efficacy of a Novel Therapy for Severe Alopecia Areata in Patients Aged 12 Years and Older.
Actas dermo-sifiliograficasEpisodic Neuropathic-Like Musculoskeletal Pain Associated With Ritlecitinib Therapy in Alopecia Universalis: A Case Report.
CureusEfficacy of oral tofacitinib in moderate to severe alopecia areata, totalis and universalis at the tertiary care hospital, Karachi.
JPMA. The Journal of the Pakistan Medical AssociationBritish Association of Dermatologists living guideline for managing people with alopecia areata 2025.
The British journal of dermatologyAlopecia universalis following human papillomavirus vaccine administration: a case report.
Clinical and experimental vaccine researchReal-World Effectiveness of JAK Inhibitors for Alopecia Totalis and Alopecia Universalis: A Single-Center Experience.
Journal of cutaneous medicine and surgerySuccessful management of therapy-resistant chronic refractory atopic dermatitis and alopecia universalis with oral tofacitinib in a girl.
The International journal of risk & safety in medicineSystemic Treatment of Moderate to Severe Alopecia Areata in Adults: Updated Australian Expert Consensus Statement.
The Australasian journal of dermatologyEffectiveness and safety of baricitinib in severe alopecia areata: 48-week results.
Journal of the European Academy of Dermatology and Venereology : JEADVDuration of current alopecia areata episode predicts the effectiveness of baricitinib in Japanese patients with alopecia areata: a single-center retrospective study.
The Journal of dermatological treatmentPost-COVID-19 Alopecia Universalis: Autoimmune Hair Loss and the Challenge of Relapse Management.
Journal of drugs in dermatology : JDDAssociation between alopecia areata and cardiovascular disease: a systematic review and meta-analysis.
Frontiers in immunologyTwo pediatric cases of alopecia universalis with concomitant atopic dermatitis successfully treated with baricitinib.
JAAD case reportsTreatment outcomes and considerations for topical immunotherapy in patients with alopecia totalis and alopecia universalis.
Frontiers in medicineUpadacitinib for Alopecia: Current Evidence and Clinical Insights.
Skin appendage disordersVogt-Koyanagi-Harada Disease in which Poliosis and Alopecia Occurred after a Long Period of Time.
Acta dermatovenerologica Croatica : ADCAtrichia Congenita with Papular Lesions: A Report of Rare Case Showing "Cluster of Stars' Appearance on Dermoscopy".
International journal of trichologyMultiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy.
AllergyManagement of comorbid Crohn's disease and alopecia universalis with upadacitinib and oral minoxidil.
The Journal of dermatological treatmentCombination of oral tofacitinib and oral mini-pulse with betamethasone (T-OMP) for the successful treatment of long-standing alopecia universalis: A real-world experience in a recalcitrant disease.
Indian journal of dermatology, venereology and leprologyAutoimmune Polyglandular Syndrome Type 2 Presentation with Alopecia Universalis, Hashimoto's Disease, and Addison's Disease.
International medical case reports journalCorrelation between increased total serum IgE levels and clinical features in alopecia areata patients.
Frontiers in immunologyInformed clinical decisions by outfoxing human FOXN1 variants.
The Journal of allergy and clinical immunologyOral minoxidil treatment of alopecia areata.
Journal of the American Academy of DermatologyVitamin D and Alopecia Areata: From Mechanism to Therapeutic Implications.
Skin appendage disordersAssessment of Vascular Circulation in Alopecia Areata Using the FMSF Technique.
Journal of clinical medicineEfficacy of Oral Tofacitinib in Alopecia Areata, Alopecia Totalis, and Alopecia Universalis.
CureusFriend or foe: A systematic review of dupilumab and alopecia areata.
Journal of the American Academy of DermatologyRates of Infections, Malignancies, Cardiovascular Outcomes, and Death in Individuals with Hospital-treated Alopecia Areata: A Registry-based Cohort Study in Denmark.
Acta dermato-venereologicaShort-term malignancy risk of JAK inhibitors in severe alopecia areata: a multicenter cohort study.
Archives of dermatological researchEfficacy and safety of tofacitinib in patients with total and universal alopecia- A retrospective evaluation of 69 patients.
Indian journal of dermatology, venereology and leprologyImpact of Janus Kinase Inhibitors on Psychiatric and Sleep Outcomes in Alopecia Areata: A Real-World Multicenter Cohort Study.
International journal of dermatologyThe Efficacy of Off-Label Abrocitinib in Alopecia Areata: A Systematic Review.
Journal of cutaneous medicine and surgerySignificant efficacy of tofacitinib from China in the treatment of alopecia areata: a case report.
Frontiers in immunologyAlopecia areata in solid organ transplant recipients: A retrospective analysis.
JAAD internationalA First Case of Complete Resolution of Hair Loss in a Patient With Rheumatoid Arthritis and Concomitant Alopecia Universalis Treated With Filgotinib.
International journal of dermatologyEfficacy of baricitinib in moderate alopecia areata, severe alopecia areata, alopecia totalis, and alopecia universalis: A real-world comparative study.
Journal of the American Academy of DermatologyAlopecia universalis and type 1 diabetes mellitus both successfully controlled with baricitinib in a patient with autoimmune polyglandular syndrome type 3A.
The Journal of dermatologyEvaluation of SALT score severity in correlation with trichoscopic findings in alopecia areata: a study of 303 patients.
Archives of dermatological researchEpidemiology of Pediatric Alopecia Areata.
Pediatric dermatologySystemic Therapies for Pediatric Alopecia Areata.
Pediatric dermatologyAlopecia Universalis: Never Give Up?
Journal of drugs in dermatology : JDDSwitching JAK inhibitors: evaluating baricitinib's effectiveness in alopecia areata after tofacitinib failure.
Archives of dermatological researchCommon variable immunodeficiency 10 due to a novel variant of NFKB2 and presenting as alopecia universalis and vitiligo.
Clinical and experimental dermatologyUnexpected Extensive Hair Whitening Following Baricitinib Treatment for Alopecia Universalis: A Case Report and Mechanistic Insights.
CureusBaricitinib-Induced Remission of Alopecia Universalis in a Child with NFKB2-Associated Immune Dysregulation.
Journal of clinical immunologyAlopecia Universalis in a Multiple Sclerosis Patient After Switching From Rituximab to Ocrelizumab: A Case Report.
International journal of rheumatic diseasesIdiopathic Developmental Dysplasia of Hip in a Female Child with a Rare Epidermal Syndrome- A Case Report.
Journal of orthopaedic case reportsAlopecia Areata Following the Use of Belimumab in a Patient with Systemic Lupus Erythematosus and Arthritis Who Responded Well to Baricitinib: A Case Report.
The American journal of case reportsA scoping review of alopecia areata and its relationship to COVID-19 vaccinations.
Archives of dermatological researchHair regrowth in a patient with alopecia universalis and psoriasis vulgaris during deucravacitinib therapy.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDGSudden improvement of alopecia universalis and psoriatic arthritis while receiving upadacitinib: a case-based review.
ReumatismoOutcomes of down-titration in patients with severe scalp alopecia areata initially treated with baricitinib 4-mg: Week 152 data from BRAVE-AA2.
Journal of the American Academy of DermatologyBiallelic pathogenic variants in the LSS gene cause congenital alopecia-cataract syndrome.
The Journal of dermatologyBritish Association of Dermatologists living guideline for managing people with alopecia areata 2024.
The British journal of dermatologyEfficacy and safety of ritlecitinib, an oral JAK3/TEC family kinase inhibitor, in adolescent and adult patients with alopecia totalis and alopecia universalis.
The Journal of dermatologyMyeloproliferative disorder associated with alopecia universalis.
JAAD case reportsPatterns of misdiagnosis in adults with alopecia areata: an analysis using the NIH's All of Us database.
International journal of dermatologyComparative investigation of immune-related biomarkers related to alopecia areata subtypes.
Archives of medical science : AMSConcomitant management of alopecia universalis and ulcerative colitis with upadacitinib.
Internal medicine journalAssessing a measure for Quality of Life in patients with severe Alopecia Areata: a multicentric Italian study.
Frontiers in public healthAlopecia universalis with IL-12-RB1 and STAT4 mutations effectively treated with upadacitinib.
JAAD case reportsTofacitinib in the Management of Alopecia Universalis.
International journal of trichologyThe Association between Number of Follicular Stelae and Severity and Treatment Response of Alopecia Areata Cases: A Retrospective Study.
International journal of trichologyTofacitinib in Pediatric Alopecia Areata Totalis and Alopecia Universalis: A Retrospective Analysis From India.
Journal of cutaneous medicine and surgeryComparison of efficacy and safety of tofacitinib and azathioprine in patients with alopecia areata and variants: a double-blind, randomized controlled trial.
Archives of dermatological researchSuccessful treatment of severe atopic dermatitis and alopecia universalis with upadacitinib in a 29-year-old male patient.
The journal of allergy and clinical immunology. GlobalEmergence of Janus kinase inhibitors led to increase in proportion of severe alopecia areata patients receiving treatment: A retrospective cohort study.
Journal of the American Academy of DermatologyTreatment Response to Diphenylcyclopropenone in Patients with Alopecia Totalis/Universalis.
International journal of trichologyDiphenylcyclopropenone alleviates trachyonychia in alopecia universalis.
International journal of dermatology"Hair is your crown and glory" - Black women's experiences of living with alopecia and the role of social support.
Health psychology reportThe Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995-2016.
Dermatology and therapyC-reactive protein as a novel biomarker for vitamin D deficiency in alopecia areata.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)Efficacy and safety of topical corticosteroid treatment under occlusion for severe alopecia areata in children: a single-centre retrospective analysis.
Clinical and experimental dermatologyA Real-World Study of Steroid-Free Monotherapy with Tofacitinib in Severe and Therapy-Recalcitrant Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Cases: A Retrospective Analysis.
Indian dermatology online journalA rare case of alopecia universalis.
The Pan African medical journalEuropean expert consensus statement on the systemic treatment of alopecia areata.
Journal of the European Academy of Dermatology and Venereology : JEADVCorneal Transplant Rejection and Alopecia Areata Universalis in a Patient With Severe Atopic Dermatitis on Dupilumab.
Actas dermo-sifiliograficasSuccessful Remission with Combination of Diphenylcyclopropenone and Apremilast in Refractory Extensive Alopecia Areata.
International journal of trichologyAlopecia Universalis Treated With Tofacitinib: The Role of JAK/STAT Inhibitors in Hair Regrowth.
CutisIntralesional Pentoxifylline Injection Versus Triamcinolone Acetonide in Treating localized Alopecia Areata: A Comparative Study.
The Journal of clinical and aesthetic dermatologyEffective management Alopecia totalis by Ayurveda - A case report.
Journal of Ayurveda and integrative medicineRapid hair regrowth in an alopecia universalis patient with deucravacitinib: A case report.
SAGE open medical case reportsThe Efficacy and Adverse Effects of Corticosteroid Pulse Therapy in Alopecia Areata: A Review Article.
Dermatology practical & conceptualThe Gut and Skin Microbiome in Alopecia: Associations and Interventions.
The Journal of clinical and aesthetic dermatologyPost-Traumatic Stress Disorder in Patients with Alopecia Areata: A Survey Study in the USA.
Skin appendage disordersCase report: Dupilumab therapy for alopecia areata in a 4-year-old patient resistant to baricitinib.
Frontiers in medicineTreatments for alopecia areata: a network meta-analysis.
The Cochrane database of systematic reviewsAlopecia areata: What's new in the epidemiology, comorbidities, and pathogenesis?
Journal of dermatological scienceModified Mediterranean Diet With Anti-Inflammatory Features and Oral Butyrate Supplementation Appears to Have No Effect in Cases of Alopecia Areata Universalis and Totalis: Experience With 20 Patients.
Actas dermo-sifiliograficasEfficacy of Baricitinib in Patients with Various Degrees of Alopecia Areata Severity: Post-Hoc Analysis from BRAVE AA1 and BRAVE AA2.
Dermatology and therapyTreatment Patterns for Alopecia Areata in the US.
JAMA dermatologySurvey of pediatric dermatologist views on treatment for alopecia areata.
JAAD internationalHair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the ALLEGRO Phase 2b/3 Study.
Dermatology and therapyCommonly Associated Disorders with Complete Scalp Alopecia in Early Childhood: A Review.
International journal of trichologyOverall and demographic subgroup incidences of alopecia areata, alopecia totalis, and alopecia universalis in the United States.
Journal of the American Academy of DermatologyAlopecia Universalis in an Elderly Chinese Man Induced by Sacubitril/Alisartan, a Novel Angiotensin Receptor-Neprilysin Inhibitor.
Journal of inflammation researchReal-World Treatment Patterns among Patients with Alopecia Areata in the USA: A Retrospective Claims Analysis.
Acta dermato-venereologicaJanus kinase inhibitors for alopecia areata.
Journal of the American Academy of DermatologyTreatment of Alopecia Universalis in a Child with Down Syndrome.
Indian journal of pediatricsSuccessful treatment of alopecia universalis with abrocitinib: a case report.
The Journal of dermatological treatmentClinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review.
GenesAlopecia universalis after injection of messenger RNA COVID-19 vaccine. A case report.
IDCasesA novel predictive model for the recurrence of pediatric alopecia areata by bioinformatics analysis and a single-center prospective study.
Frontiers in medicineIncidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database.
Dermatology and therapyPrevalence of autoimmune and inflammatory diseases and mental health conditions among an alopecia areata cohort from a US administrative claims database.
The Journal of dermatologySintilimab-induced Alopecia Universalis in a Patient With the Anti-tumor Effect of Complete Remission After Hepatectomy.
Journal of immunotherapy (Hagerstown, Md. : 1997)A retrospective study on the clinical characteristics and prognosis of alopecia totalis and universalis: An update on prognosis.
The Journal of dermatologyViral-Induced Rapidly Progressive Alopecia Universalis: A Case Report and Literature Review.
CureusThe Association between the Number of Follicular Stelae and Severity and Treatment Response of Alopecia Areata Cases: A Retrospective Study.
International journal of trichologyThe frequency of fatty liver in patients with alopecia areata: A case-control study.
Journal of cosmetic dermatologyUpadacitinib for Successful Treatment of Alopecia Universalis in a Child: A Case Report and Literature Review.
Acta dermato-venereologicaSuccessful treatment of concomitant alopecia universalis and Crohn's disease with upadacitinib: A case report.
SAGE open medical case reportsAssessing Patient's Values When Selecting Treatments for Alopecia Areata: A Cross-Sectional Survey Study.
Skin appendage disordersPossible mechanisms mediating complete regrowth of hair following scalp tattooing in alopecia universalis.
JAAD case reportsTrends in Prevalence and Incidence of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Among Adults and Children in a US Employer-Sponsored Insured Population.
JAMA dermatologyOverall and Racial and Ethnic Subgroup Prevalences of Alopecia Areata, Alopecia Totalis, and Alopecia Universalis.
JAMA dermatologyA Case Series and Literature Review of Telogen Effluvium and Alopecia Universalis after the Administration of a Heterologous COVID-19 Vaccine Scheme.
VaccinesHydroxychloroquine for granuloma annulare: A case report on secondary hair growth in alopecia universalis.
SAGE open medical case reportsBaricitinib effectiveness in patients with alopecia universalis and rheumatoid arthritis.
Italian journal of dermatology and venereologyAn impressive case of alopecia universalis after COVID-19 vaccination: a coincidental finding or a consequence?
European review for medical and pharmacological sciencesAlopecia Universalis in an Adolescent Successfully Treated with Upadacitinib-A Case Report and Review of the Literature on the Use of JAK Inhibitors in Pediatric Alopecia Areata.
Dermatology and therapyDupilumab as a Therapeutic Approach in Alopecia Universalis.
CutisTreatment of moderate-to-severe alopecia areata in adolescents with baricitinib: A retrospective review of 29 patients.
Journal of the American Academy of DermatologyFOXN1 Gene Considerations in Severe Combined Immunodeficiency Treatment in Children.
CureusComplete regrowth of hair following scalp tattooing in a patient with alopecia universalis.
JAAD case reportsEffective treatment of alopecia universalis with oral upadacitinib.
JAAD case reportsClinical response to oral tofacitinib in pediatric patients with alopecia areata.
JAAD case reportsEpidemiology of alopecia areata in Hispanic/Latinx patients.
Journal of the American Academy of DermatologyAnxiety, depression, and quality of life in children and adults with alopecia areata: A systematic review and meta-analysis.
Frontiers in medicineRetrospective evaluation of clinical profile and comorbidities in patients with alopecia areata.
Northern clinics of IstanbulTreatment of alopecia areata of the beard with baricitinib.
Journal of the American Academy of DermatologyA Practical Approach to the Treatment of Alopecia Areata.
Indian dermatology online journalAlopecia Areata: Case report and review of pathophysiology and treatment with Jak inhibitors.
Journal of autoimmunityAlopecia Universalis after Treatment with Simvastatin and Ezetimibe: Affects on Family.
Arquivos brasileiros de cardiologiaTreatment of longstanding alopecia areata universalis of the eyebrows/facial hair with oral and topical tofacitinib.
Dermatology online journalAlemtuzumab-induced alopecia universalis and transient accommodation spasm in a patient with multiple sclerosis.
Therapeutic advances in neurological disordersThe Role of Antihistamines and Dupilumab in the Management of Alopecia Areata: A Systematic Review.
Journal of drugs in dermatology : JDDReal-world experience and long-term evaluation of tofacitinib in refractory alopecia areata: A prospective, open-label, single-center study in Asian Arab population.
Dermatologic therapyA first case of childhood chronic inflammatory demyelinating polyneuropathy associated with alopecia universalis.
Brain & developmentRituximab-Induced Alopecia Universalis in a Patient With Bullous Pemphigoid.
Journal of drugs in dermatology : JDDImprovement of atopic dermatitis and alopecia universalis with dupilumab.
Dermatology reportsCase Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?
Frontiers in immunologyAssessment of alopecia areata universalis successfully treated with upadacitinib.
International journal of dermatologyTopical diphenylcyclopropenone plus topical 0.5% anthralin versus topical diphenylcyclopropenone alone for the treatment of chronic extensive alopecia areata: A split-scalp, double-blind, controlled study.
International journal of trichologyAlopecia universalis with unusual histopathologic features after vaccination with ChAdOx1 nCoV-19 (AZD1222).
JAAD case reportsIs there a link between alopecia areata and gut?
Journal of cosmetic dermatologyNot just thinning: A case of alopecia universalis after mild COVID-19.
JAAD case reportsEconomic Impact of Home-Use versus Office-Use Diphenylcyclopropenone in Extensive Alopecia Areata.
Skin appendage disordersSuccessful treatment of chronic severe alopecia areata with abrocitinib.
The Australasian journal of dermatologyPhase 2 randomized, dose-ranging trial of CTP-543, a selective Janus Kinase inhibitor, in moderate-to-severe alopecia areata.
Journal of the American Academy of DermatologyA case of atopic dermatitis with alopecia universalis in a patient treated with abrocitinib.
JAAD case reportsDefining Severity in Alopecia Areata: Current Perspectives and a Multidimensional Framework.
Dermatology and therapyAll-cause health care resource utilization and costs among adults with alopecia areata: A retrospective claims database study in the United States.
Journal of managed care & specialty pharmacyCould mean platelet volume be used as a marker for activity and severity index of alopecia areata?
The Turkish journal of pediatricsTopical bimatoprost in the treatment of eyelash loss in alopecia totalis and universalis: A prospective, open-label study.
Dermatologic therapyRefractory alopecia universalis associated with dermatomyositis successfully treated with tofacitinib.
Modern rheumatology case reportsA phase 2a randomized vehicle-controlled multi-center study of the safety and efficacy of delgocitinib in subjects with moderate-to-severe alopecia areata.
Archives of dermatological researchAlopecia Universalis Associated with Hyperthyroidism Treated with Azathioprine and Hydroxychloroquine: A Case Report.
JNMA; journal of the Nepal Medical AssociationAlopecia universalis improvement following risankizumab in a psoriasis patient.
Journal of the European Academy of Dermatology and Venereology : JEADVRemission of Alopecia Universalis after 1 Year of Treatment with Dupilumab in a Patient with Severe Atopic Dermatitis.
Skin appendage disordersSuccessful Therapy of Alopecia Universalis Using a Combination of Systemic Methotrexate and Corticosteroids and Topical 5% Minoxidil.
Clinical, cosmetic and investigational dermatologyClinical response to adjunctive platelet-rich plasma injections in a patient with alopecia universalis on oral tofacitinib.
JAAD case reportsIntramuscular Corticosteroid Therapy in the Treatment of Alopecia Areata: A Time-to-Event Analysis.
Drug design, development and therapyAttenuation of Autoimmune Phenomena in a Patient with Autoimmune Polyglandular Syndrome Type 1.
Case reports in endocrinologyRecovery of Alopecia Universalis with Associated Nail Dystrophy Treated with Tofacitinib: A 6-year-old Child's Case Report.
International journal of trichologyTreatment of alopecia totalis/universalis/focalis with vitamin D and analogs: Three case reports and a literature review.
World journal of clinical pediatricsRitlecitinib: an investigational drug for the treatment of moderate to severe alopecia areata.
Expert opinion on investigational drugsHair regrowth and maintenance in alopecia universalis patient treated with nonablative Er:YAG laser.
Clinical case reportsEstimation of CD3, CD4, and CD8 in Iraqi patients with alopecia areata and alopecia universalis.
Journal of cosmetic dermatologyAlopecia areata and tofacitinib: a prospective multicenter study from a Saudi population.
International journal of dermatologyThe close resemblance between patients with severe alopecia areata and those with cancer: What hair tells us about wellness or grave illness.
Journal of the American Academy of DermatologyIt is all alopecia areata: It is time to abandon the terms alopecia totalis and alopecia universalis.
Journal of the American Academy of DermatologyTofacitinib Treatment in Patients With Active COVID-19 Infection.
Cureus[Hair growth with dupilumab in alopecia areata universalis and atopic dermatitis].
Dermatologie (Heidelberg, Germany)Dupilumab for the treatment of alopecia areata in children with atopic dermatitis.
JAAD case reportsHairless Gene Nonsense Mutations in Alopecia Universalis: A Case Report.
Iranian journal of public healthAlopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management.
Clinical reviews in allergy & immunologyAlopecia Areata: An Autoimmune Disease of Multiple Players.
ImmunoTargets and therapyAlopecia Universalis Occurring after Alemtuzumab Treatment for Multiple Sclerosis. A Two-Year Follow-Up of Two Patients.
International journal of environmental research and public healthAssociation of Alopecia Areata With Attention-Deficit/Hyperactivity Disorder Stimulant Medication: A Case-Control Study.
Ochsner journalAdiponectin as a novel biomarker of disease severity in alopecia areata.
Scientific reportsAtrichia with papular lesions: a differential diagnosis of alopecia universalis not to be missed.
Journal of the European Academy of Dermatology and Venereology : JEADVA case of HIV-associated generalized syphilitic alopecia mimicking alopecia universalis.
International journal of dermatologyT-Cell-Driven Fibroinflammation Inducing Follicular Dedifferentiation in Alopecia Areata and IgG4-Modified Disease.
The American Journal of dermatopathologyUnexpected hair regrowth in a woman with longstanding Alopecia universalis.
GMS ophthalmology casesAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
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Comunidades
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Stem cell-based therapies for alopecia areata: a narrative review.
- Case Report: Vitiligo and Alopecia Universalis Following Rituximab Therapy in a Patient with Myasthenia Gravis.
- From Bald to Bold: Reversal of Alopecia Totalis in an Adolescent Using Dupilumab Monotherapy.
- Psoriasis Course in Patients with Alopecia Areata Undergoing Baricitinib Therapy.
- Clinical characteristics, subtype classification, and prognostic factors of ophiasis: A retrospective study of 150 patients with therapeutic implications.
- Regrowth of Eyebrows in a Previous Steroid Non-Responder With Alopecia Universalis After Ritlecitinib Treatment.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:701(Orphanet)
- OMIM OMIM:203655(OMIM)
- MONDO:0008757(MONDO)
- GARD:614(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q5075435(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
