The role of zinc transporter 1 (ZnT1) in health and disease: From molecular mechanisms to therapeutic opportunities.

The ROS-triggered antibacterial mechanism of zinc oxide nanoparticles against Xanthomonas citri subsp. citri for citrus canker management.

In Vitro Studies of the Effects of Antithrombotic Zn-Dipicolylamine-Harboring Liposomes (DPALs) on Serum Albumin and Human Umbilical Vein Endothelial Cells.

Molecular and immunological heterogeneity of eosinophilic esophagitis: Insights and subtyping.

Bacterial reporter-paired scRNA sequencing reveals cross talk between zinc starvation and zinc toxicity in macrophage antibacterial defense.

bZIP63.5 Regulates a Zinc-Finger Mediated Detoxification Network in Trichoderma Harzianum for Enhanced Biocontrol of Alternaria alternata.

A Novel Autoimmune Presentation of Wiskott-Aldrich Syndrome: Type 1 Diabetes.

Nutrigenomic profiling identifies ZIP10 (SLC39A10) as a regulator of erythroid zinc homeostasis with genetic associations to anemia risk.

Type 1 Diabetes: A Review.

MG53 mediates skeletal muscle-liver cross-talk and enhances alcohol metabolism in alcoholic liver disease.

Genetic dissection of signalling pathways that mediate iron-related tumor growth in a Drosophila model.

Ethanol Alters DNMT1/3a/3b Expression Profile, Promotes Persistent DNA Hypomethylation in Human Brain Endothelial Cells and Impairs Late Cortical Angiogenesis.

An emerging role for synaptic Zn2+ in substance use disorders.

ZFT is the major iron and zinc transporter in Toxoplasma gondii.

MT1E binds to LncRNA NEAT1 to regulate SLC39A14-mediated ferroptosis in the pathogenesis of aortic dissection.

Cryo-EM Brings the Mechanisms of Activation, Inactivation, and Inhibition of Ryanodine Receptors into Focus.

Molecular Genetics of β-Cell Compensation in Gestational Diabetes Mellitus: Insights from CDKAL1, SLC30A8 and HHEX.

SLC30 (ZnT) and SLC39 (ZIP) zinc transporter families: from gatekeepers of zinc homeostasis to promoters of tumorigenesis and targets for clinical therapy.

Core-shell heterostructured nanozyme for alveolar echinococcosis treatment via targeted electron transfer and catalytic reactive oxygen species generation.

Integrated multi-omics and machine learning identify an interaction between SLC39A11 and phosphoinositide metabolism in deep vein thrombosis.

Roles of zinc in the gut-liver axis.

Associations of body weight and COVID-19 with autoimmunity in pediatric new-onset type 1 diabetes: results from the prospective DPV registry.

ZNF454-FSTL3 axis inhibits colorectal cancer progression by inhibiting HIF-1α-mediated glycolysis in hypoxia.

Zinc-α₂-glycoprotein overexpression attenuates gasdermin D-mediated pyroptosis in dopaminergic neurons by suppressing reactive oxygen species/mitogen-activated protein kinase signaling.

ZIP10 drives radioresistance and malignant progression in lung adenocarcinoma by inhibiting the Hippo pathway via a Zinc-LATS axis.

The role of zinc homeostasis in major depressive disorder: heterogeneous pathological mechanisms and therapeutic implications.

ZnT3-TMEM163 Mediates Zinc Homeostasis Imbalance Induced Neurodegeneration in Hippocampus.

DIA-based quantitative proteomics reveals the mechanism of foliar spraying glycine betaine and zinc in improving the quality of dry-cultivated rice.

Deletion of tonB1 in Pseudomonas aeruginosa impairs zinc homeostasis and pathogenicity.

Impact of bovine respiratory disease on tissue-specific regulation of Zn and vitamin a metabolism and apparent absorption and retention of trace minerals.

Molecular Portrait of Autoantigens in Type 1 Diabetes.

Iron metabolism disorder promotes postovulatory oocyte aging by inducing oxidative stress damage.

Dravet Syndrome Patient-Derived Neural Cells Present Altered Levels of Potassium, Copper, and Zinc.

A novel accessible in vitro model of proliferative vitreoretinal diseases shows facilitated epithelial mesenchymal transition through aquaporin-1.

Cluster-specific genetic associations of CDKAL1, CDKN2A, CDKN2B, HHEX, KCNQ1, MTNR1B, PAX4, SLC30A8, TCF7L2, and UBE2E2 variants in new onset type 2 diabetes.

Structural insights into zinc piracy by Neisseria gonorrhoeae to overcome nutritional immunity.

O08 The elemental clue: a case series of Acrodermatitis enteropathica in a tertiary centre.

Small RNA-mediated regulation of cross-kingdom gene expression in sugar beet genotypes resistant and susceptible to rhizomania.

IDEDNIK syndrome: a newly recognized rare genetic disorder caused by AP1S1 and AP1B1 mutations.

Modulation of adipose inflammation and mitochondrial pathways by a yeast-derived β-1,3/1,6-glucan and vitamin complex: an open-label pilot study of Lalmin® immune pro in older overweight adults.

A New Toolbox to Label Zinc-MTF1 Responsive Neuronal Populations Unravels Cellular Congruence between MTF1 Responses and T-type Calcium Channelopathies in an Experimental Model of Epilepsy.

Loss-of-function variant of SLC30A8 rs13266634 (C > T) protects against type 2 diabetes by stabilizing ZnT8: Insights from epidemiological and computational analyses.

Heterozygous Variants of the SLC39A4 Gene and Possible Increased Risk for Developing Acrodermatitis Enteropathica with Kaposi's Varicelliform Eruption.

Identification of genes underlying nigrostriatal iron accumulation: transcriptome-wide association study of iron-sensitive brain MRI.

Chios Mastic Gum Extract Enhances Antioxidant Defense in Zebrafish.

Zinc bioavailability in alcohol-associated liver disease: Mechanisms and therapeutic implications.

Zinc transporter dynamics in the pathogenesis of 2,4,6-trinitrobenzenesulfonic acid/ethanol-induced ileitis in mice.

Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases.

Perturbations of Zinc Homeostasis and Onset of Neuropsychiatric Disorders.

SLC30A3 as a Zinc Transporter-Related Biomarker and Potential Therapeutic Target in Alzheimer's Disease.

Selective knockout of murine glutamic acid-rich protein 2 significantly alters dark continuous noise in rod photoreceptors.

Generation of hiPSC-Derived Brain Microvascular Endothelial Cells Using Directed Differentiation and Transcriptional Reprogramming.

Discovery of a Selective Inhibitor of ZIP14 with Therapeutic Potential for Cancer-associated Cachexia.

Mitochondrial protein TOMM7 alleviates diabetic kidney disease by regulating mitophagy via intracellular redistribution of phospholipase PLA2G6.

Synergistic effects of Zn2+/Ca2+ crosslinking on alginate-chitosan semi-interpenetrating networks: mechanical and pH responsive properties.

Misclassified latent autoimmune diabetes in adults within Māori and Pacific adults with type 2 diabetes in Aotearoa New Zealand.

Differential ion selectivity and disease-associated dysfunction of TRPML channels revealed by patient and engineered mutants.

Effects of rs3802177 G/A polymorphism on SLC30A8 mRNA and hsa-miR-183-5p in Malay women with gestational diabetes mellitus.

A homology-based 3D model and structure-function studies reveal key elements for divalent metal ion transporter ZIP8 (SLC39A8) function.

The SWI/SNF chromatin-remodeling subunit DPF2 regulates macrophage inflammation in intestinal injury via the CACNA1D-mediated MAPK pathway.

ZNF529 up-regulation speeds up progression and induces tyrosine kinase inhibitor resistance in hepatocellular carcinoma.

Protein-Mediated Virulence in Mycobacterium tuberculosis.

Loss of Aquaporin-1 in Tumor Cells Fosters Intrahepatic Cholangiocarcinoma Progression.

ZNF334 truncation mutation drives cold-induced autoinflammation.

Mass Spectrometry-Based Comparative Analysis of N-Glycosylation Alterations in Three Human Body Fluids in Parkinson's Disease.

Atypical presentation of Acrodermatitis enteropathica in a child: later onset with life-threatening severe extensive dermatitis and septic shock.

Zinc and Adipose Organ Dysfunction: Molecular Insights into Obesity and Metabolic Disorders.

PDZK1, a direct target of Gli2, promotes FGFR3 trafficking and cell proliferation in colorectal cancer.

PARIS/ZNF746 DNA-binding domain deficiency promotes adipose tissue hyperplasia and hepatic lipid accumulation.

Association of acyl-CoA oxidase-like gene polymorphisms with risk, onset age, and beta-cell function of type 1 diabetes in Chinese.

Genetic insights into bovine spastic syndrome (Crampy) in Holstein dairy cattle.

Zinc transporter proteins in the retina as potential biomarkers for staging early Alzheimer's disease: Comparative analysis in human and mouse models.

Targeted genome editing of ZKSCAN3 mitigates the neurotoxicity caused by mutant HTT (huntingtin) in a Huntington disease animal model and three-dimensional cell culture of Huntington disease.

Zinc Ameliorates Inflammation and Sperm Parameters in Rats With Experimental Autoimmune Prostatitis.

Nutrigenetics and metabolic syndrome: evidence from a systematic review of the literature.

Molecular mechanisms of SLC30A10-mediated manganese transport.

Predictors of Transitions From GADA as the Initial Autoantibody to Multiple Autoantibodies of Type 1 Diabetes in Children at Risk by a Dynamic Prediction Model.

SLC39A5 promotes the malignant progression of gastric cancer by activating BATF phosphorylation.

UK best practice recommendations for children and young people <18 years with pre-stage 3 type 1 diabetes, on behalf of the British Society for Paediatric Endocrinology and Diabetes (BSPED).

Zinc Transporters in Diseases, Including Diabetes and Related Conditions.

Unraveling the Diversity of RANBP2: Protein Isoforms and Implications for Cellular Function and Human Disease.

Zinc protoporphyrin-triggered ferroptosis plays a critical role in renal proximal tubular cell damage and chronic kidney disease.

Endothelial GATAD1 Exacerbates Blood-brain Barrier Dysfunction in Ischemic Stroke through Caveolae-mediated Transcytosis.

Aberrant N-glycosylation may be a therapeutic target in carriers of a common and highly pleiotropic variant in the manganese transporter ZIP8.

SLC39A8-mediated zinc dyshomeostasis potentiates kidney disease.

Quantitative Control of Zn2+ Photorelease: A Step toward Decoding Mechanisms of Subsecond Metal Signaling in the Brain.

ZnO Nanoparticles Interacts With Unique Serum Proteins and Induce Stress Signaling During Hepatoxicity - A Proteomics and Molecular Pathways Study.

Ciprofloxacin enhances RSL3-induced ferroptosis by promoting mitochondrial Zn2+ accumulation via the STING1-CAV2 pathway.

Self-Doped Cu2+xZn1-xSnSe4 Nanosheets for Enhanced Thermoelectric Catalytic-Ferroptotic Therapy.

A TRPM2-Driven Signalling Cycle Orchestrates Abnormal Inter-Organelle Crosstalk in Cardiovascular and Metabolic Diseases.

Metallothionein and Other Factors Influencing Cadmium-Induced Kidney Dysfunction: Review and Commentary.

Effect of dietary zinc supplementation on the gastrointestinal microbiome and host gene expression in the Shank3B-/- mouse model of autism spectrum disorder.

Type 2 diabetes mellitus and zinc dysregulation: From basic and epidemiological evidence to interventions.

Diabetes, Celiac, and Thyroid-Related Autoantibodies in HLA Genotyped Ethiopian Children and Adolescents With Type 1 Diabetes: A Cross-Sectional Study.

Unravelling the complex interplay between zinc, iron and their synergistic effect on LCPUFA metabolism in preeclampsia.

Engineering biology and chemical approaches to the construction of vitamin B12 analogues and antivitamins B12 as probes and therapeutic agents.

Analysis of novel zinc-binding proteins in the cell wall of Corynebacterium diphtheriae.

Pathogenic ZNF319 variant disrupts nuclear localization and transcriptional regulation to cause a novel form of autosomal recessive leukodystrophy.

SOX4-ZIP14-zinc metabolism mediates oncogenesis and suppresses T cell immunity in nasopharyngeal carcinoma.

Role of CNNM4 in the progression of cholangiocarcinoma: implications for ferroptosis and therapeutic potential.

FGA139, a novel cysteine protease inhibitor, exhibits anti-inflammatory and neuroprotective activity and reveals microglial modulation via multi-omics profiling.

Zinc induces neuronal autophagy via HMGB1 nuclear translocation in acute cerebral ischemia.

Rationale Design of a Zn(II)-Coordinated, Cell Penetrating, and Functionalized Tetrapeptide Self-Assembly for Delivery of Chemotherapeutic Drugs to Folic Acid Receptor-Expressing Cancer Cells.

SLC39A13 Regulates Heart Function via Mitochondrial Iron Homeostasis Maintenance.

A structural perspective of transmembrane transport of zinc by ZnT and ZIP transporters.

Functional Cargo in Membrane Vesicles From a Citrus Pathogen.

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy.

ZnTs: Key Regulators of Zn2+ Homeostasis in Diseases.

SerpinA3N inhibits mitochondrial complex I activity to prevent neuron ferroptosis following cerebral ischemic stroke.

The Role of Lysine Tyrosylquinone Containing Oxidases in Progression of Solid Tumors.

ZIP10 as a potential therapeutic target in acute myeloid leukaemia.

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models.

Lysosomal zinc nanomodulation blocks macrophage pyroptosis for counteracting atherosclerosis progression.

Inhibition of Hedgehog signaling does not mitigate polycystic kidney disease severity in a Pkd1 mutant mouse model.

Zinc sulfate improves insulin resistance, oxidative stress and apoptosis in liver tissues of PCOS rats through the NF-κB pathway.

Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics.

Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages.

Effect of Alpha-1 Antitrypsin Deficiency on Zinc Homeostasis Gene Regulation and Interaction with Endoplasmic Reticulum Stress Response-Associated Genes.

Pitfalls in the Diagnosis of Wilson Disease.

Etiologic Determinants and Characteristics of Diabetes in Haitian Youth (EDDHY Study).

Trace Element Deficiency in Axial Spondyloarthritis and Psoriatic Arthritis in Relation to Markers of Inflammation and Remission.

Alteration of Hair Melanin in Patients With Mowat-Wilson Syndrome: The Role of the ZEB2 Gene in Regulating Melanogenesis Through SLC45A2.

Downregulation of the Zinc Transporter ZIP13 (Slc39a13) Leads to Ferroptosis by Inhibiting Mitochondrial Iron-Sulfur Cluster Biosynthesis and Induces Ischemia/Reperfusion Injury in Mouse Hearts.

Establishing the performance and acceptability of dried blood spot sampling to screen for islet-specific autoantibodies.

ZIP8 modulates ferroptosis to drive esophageal carcinoma progression.

Cadmium exposure and its role in joint disease: A brief review of experimental and population-based evidence.

A zinc transporter drives glioblastoma progression via extracellular vesicles-reprogrammed microglial plasticity.

Nutritional Value and Health Implications of Meat from Monogastric Animals Exposed to Heat Stress.

Association of C1QTNF6 gene polymorphism with risk and clinical features of type 1 diabetes in Chinese: implications for ZnT8A and beta-cell function.

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol.

Modulation of NMDA receptor signaling and zinc chelation prevent seizure-like events in a zebrafish model of SLC13A5 epilepsy.

A Compound Screen Based on Isogenic hESC-Derived β Cell Reveals an Inhibitor Targeting ZnT8-Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress-Induced Cell Death.

Correlative analysis of metallomic gene expression and metal ion content within the mouse hippocampus.

The TRPV3 channel is a mediator of zinc influx and homeostasis in murine oocytes.

Two-pronged approach: Therapeutic effect of biological scaffold combined with immune intervention and β-cell replacement on type 1 diabetic mice.

Calprotectin elicits aberrant iron starvation responses in Pseudomonas aeruginosa under anaerobic conditions.

Modulation of ZnT-1 by Let7a unveils a therapeutic potential in amyotrophic lateral sclerosis.

Protocatechuic Acid Reduces Liver Fatty Acid Uptake in HFD-Fed Mice Associated With the Inhibition of DHHC5-Mediated CD36 Palmitoylation.

ZnT6-mediated Zn2+ redistribution: impact on mitochondrial fission and autophagy in H9c2 cells.

Zinc ion dyshomeostasis in autism spectrum disorder.

Micronutrient Biofortification in Wheat: QTLs, Candidate Genes and Molecular Mechanism.

Vitamin D deficiency is common among Polish children with newly diagnosed type 1 diabetes mellitus.

Impact of zinc on immunometabolism and its putative role on respiratory diseases.

ZntR is a critical regulator for zinc homeostasis and involved in pathogenicity in Riemerella anatipestifer.

N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) as a novel chelator for Wilson's disease.

Zinc Attenuates Prostate Hyperplasia and Inflammatory Injury in Obese Rats by Regulating Zinc Homeostasis and Inhibiting the JAK1/STAT3 Pathway.

L-theanine ameliorates traumatic-brain-injury-induced hippocampal neuronal death in rats.

ANP Increases Zn2⁺ Accumulation During Reperfusion in Ex Vivo and In Vivo Hearts.

Urinary trace elements and thyroid nodule formation in a longitudinal cohort of older women: Findings from KoGES.

ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.

Islet autoantibodies in Thai individuals diagnosed with type 1 diabetes before 30 years of age: a large multicentre nationwide study.

The TRPM7 chanzyme in smooth muscle cells drives abdominal aortic aneurysm in mice.

The sterol-regulating human ARV1 binds cholesterol and phospholipids through its conserved ARV1 homology domain.

Correlation of Serum Zinc Levels with Hepatic Encephalopathy Severity in Patients with Decompensated Liver Cirrhosis: A Prospective Observational Study from Egypt.

Minerals and Human Health: From Deficiency to Toxicity.

Tumor-derived miR-203a-3p potentiates muscle wasting by inducing muscle ferroptosis in pancreatic cancer.

Human genetic variants in SLC39A8 impact uptake and steady-state metal levels within the cell.

Oxylipin dynamics in dairy cows during clinical ketosis and after treatment with niacin and flunixin meglumine.

SLC39A10 is a key zinc transporter in T cells and its loss mitigates autoimmune disease.

The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications.

Modelling host-pathogen interactions: Galleria mellonella as a platform to study Pseudomonas aeruginosa response to host-imposed zinc starvation.

Synthesis and functional screening of novel inhibitors targeting the HDAC6 zinc finger ubiquitin-binding domain.

Zinc Transporter 9 (ZnT9) Improves Obesity-Induced Asthenospermia by Attenuating Endoplasmic Reticulum Stress (ERS).

Multifunctional Nanomedicine for Targeted Atherosclerosis Therapy: Activating Plaque Clearance Cascade and Suppressing Inflammation.

Mutations in histones dysregulate copper homeostasis leading to defect in Sec61-dependent protein translocation mechanism in Saccharomyces cerevisiae.

Deletion of metal transporter Zip14 reduces major histocompatibility complex II expression in murine small intestinal epithelial cells.

EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents.

Mammalian SLC39A13 promotes ER/Golgi iron transport and iron homeostasis in multiple compartments.

Deciphering the mineral code of urinary stones: A first look at zinc isotopes.

Trace element zinc metabolism and its relation to tumors.

Zinc homeostasis regulates caspase activity and inflammasome activation.

The Role of Trace Elements in COPD: Pathogenetic Mechanisms and Therapeutic Potential of Zinc, Iron, Magnesium, Selenium, Manganese, Copper, and Calcium.

Genetic inactivation of zinc transporter SLC39A5 improves liver function and hyperglycemia in obesogenic settings.

Research progress on the molecular structure, function, and application in tumor therapy of zinc transporter ZIP4.

Exosomal circ_001860 Promotes Colorectal Cancer Progression through the miR-582-5p/ZEB1 Axis.

Proteomics analysis in rats reveals convergent mechanisms between major depressive disorder and dietary zinc deficiency.

A Zinc Uptake Transporter ZIP1-II Is Involved in Zinc Accumulation in the Hepatopancreas of Pacific Oyster Crassostrea gigas.

Loss of the zinc receptor ZnR/GPR39 in mice enhances anxiety-related behavior and motor deficits, and modulates KCC2 expression in the amygdala.

Fluorescence chemosensing and bioimaging of metal ions using schiff base probes working through photo-induced electron transfer (PET).

The pathophysiological functions and therapeutic potential of GPR39: Focus on agonists and antagonists.

Molecular mechanisms of MAZ targeting up-regulation of NDUFS3 expression to promote malignant progression in melanoma.

ZIP7 contributes to the pathogenesis of diabetic cardiomyopathy by suppressing mitophagy in mouse hearts.

LC3B-regulated autophagy mitigates zinc oxide nanoparticle-induced epithelial cell dysfunction and acute lung injury.

Zinc finger transcription factors BnaSTOP2s regulate sulfur metabolism and confer Sclerotinia sclerotiorum resistance in Brassica napus.

Zinc Deficiency Leads to Reproductive Impairment in Male Mice Through Imbalance of Zinc Homeostasis and Inflammatory Response.

Cryo-EM structures of the zinc transporters ZnT3 and ZnT4 provide insights into their transport mechanisms.

SLC30A2-Mediated Zinc Metabolism Modulates Gastric Cancer Progression via the Wnt/β-Catenin Signaling Pathway.

The Impact of Selenium Deficiency and T-2 Toxin on Zip6 Expression in Kashin-Beck Disease.

Zinc-modulated bidirectional copper transfer across the blood-brain barrier in a porcine brain capillary endothelial cell culture model system.

Expression of Manganese Transporters ZIP8, ZIP14, and ZnT10 in Brain Barrier Tissues.

Carvedilol through ß1-Adrenoceptor blockade ameliorates glomerulonephritis via inhibition of oxidative stress, apoptosis, autophagy, ferroptosis, endoplasmic reticulum stress and inflammation.

Citrus yellow vein clearing virus infection triggers phloem remobilization of iron- and zinc-nicotianamine in citrus.

Dietary zinc status is associated with ZnT3 (SLC30A3), IL-6 gene expressions and spinal cord tissue damage in spinal cord tissue in a cuprizone-induced rat Multiple Sclerosis model.

Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation.

[Progress in drug therapy of Wilson's disease].

Myricanol represses renal fibrosis by activating TFAM and ZNRF1 to inhibit tubular epithelial cells ferroptosis.

ZIP8 A391T Crohn's Disease-Linked Risk Variant Induces Colonic Metal Ion Dyshomeostasis, Microbiome Compositional Shifts, and Inflammation.

Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart.

The ZDHHC13/ZDHHC17 subfamily: From biological functions to therapeutic targets of diseases.

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.