O rim displásico multicístico (MCDK) é uma anomalia congênita do rim e do trato urinário (CAKUT) na qual um ou ambos os rins (MCDK unilateral ou bilateral, respectivamente) são grandes, distendidos por múltiplos cistos e não funcionais.
Introdução
O que você precisa saber de cara
O rim displásico multicístico (MCDK) é uma anomalia congênita do rim e do trato urinário (CAKUT) na qual um ou ambos os rins (MCDK unilateral ou bilateral, respectivamente) são grandes, distendidos por múltiplos cistos e não funcionais.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 8 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 15 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
1 gene identificado com associação a esta condição. Padrão de herança: Not applicable.
Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:17924661, PubMed:7900999). Binds to the FPC element in the cAMP regulatory unit of the PLAU gene (By similarity). Transcriptional activity is increased by coactivator PCBD1 (PubMed:24204001)
Nucleus
Renal cysts and diabetes syndrome
An autosomal dominant disorder comprising non-diabetic renal disease resulting from abnormal renal development, and diabetes, which in some cases occurs earlier than age 25 years and is thus consistent with a diagnosis of maturity-onset diabetes of the young (MODY5). The renal disease is highly variable and includes renal cysts, glomerular tufts, aberrant nephrogenesis, primitive tubules, irregular collecting systems, oligomeganephronia, enlarged renal pelves, abnormal calyces, small kidney, single kidney, horseshoe kidney, and hyperuricemic nephropathy. Affected individuals may also have abnormalities of the genital tract.
Variantes genéticas (ClinVar)
534 variantes patogênicas registradas no ClinVar.
Vias biológicas (Reactome)
6 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Displasia renal cística difusa
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Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
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Outros ensaios clínicos
24 ensaios clínicos encontrados, 2 ativos.
Publicações mais relevantes
Unilateral Multicystic Dysplastic Kidney in a Fetus Associated With Parental Genetic and Environmental Risk Factors: A Case Report.
Multicystic dysplastic kidney (MCDK) is a congenital renal anomaly identified on prenatal ultrasound. They often arise sporadically and unilaterally. Our case involves an isolated unilateral MCDK in a fetus born to a mother with generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), and gastroesophageal reflux disease (GERD), with the father having chronic occupational lead exposure and a congenital disorder of glycosylation type 1A (PMM2-CDG). Our case highlights the multifactorial etiology of renal dysplasia and its potential role of glycosylation defects and environmental toxicity in abnormal kidney development. Contributions from genetic, environmental, and metabolic influences during nephrogenesis contribute to MCDK.
Genetic Abnormalities and Clinical Management of Fetal Genitourinary System Anomalies in Eastern China.
To investigate the correlation between genetic abnormalities and fetal genitourinary (GU) anomalies in Eastern China and to provide assistance for the clinical management of fetuses with different types of GU anomalies. Five hundred forty-five fetuses with GU anomalies were enrolled, undergoing karyotyping, copy number variation sequencing (CNV-seq) or chromosomal microarray analysis (CMA), and trio-exome sequencing (trio-ES), and received long-term follow-ups from 6 months to 7 years. The top five GU anomalies were hydronephrosis, renal agenesis, multicystic dysplastic kidney, genital cysts, and genital abnormalities. 4.77% (19/398) of chromosomal abnormalities were detected by karyotyping, and 39 CNVs were revealed in 354 cases by CNV-seq/CMA simultaneously, with 6.50% (23/354) of additional CNVs. Genetic abnormalities were more frequent in reproductive system anomalies, nonisolated, and multiple GU anomalies. Two of eight with pathogenic/likely pathogenic genes were additionally detected. Five hundred thirty-four pregnancy outcomes were obtained, including 418 (76.70%) live births with favorable outcomes, two (0.37%) intrauterine fetal deaths, and 114 (20.92%) terminations mainly due to genetic abnormalities or nonisolated anomalies. The fetuses with reproductive system anomalies, nonisolated, and multiple GU anomalies were associated with genetic abnormalities. Therefore, a closed-loop management strategy including "diagnosis-assessment-intervention-follow-up" should be provided for fetuses with GU anomalies from pregnancy to postpartum period.
Outcomes of antenatal hydronephrosis and other renal abnormalities in a population-based cohort.
Hydronephrosis, commonly detected during second trimester ultrasound screenings, can signal underlying renal abnormalities. In 2018, Sweden introduced a national guideline recommending follow-up for fetal renal pelves with an anteroposterior diameter (APD) ≥6 mm at the second trimester ultrasound. This study evaluates the impact of the guideline by assessing the incidence and resolution of hydronephrosis and other renal abnormalities. Secondary outcomes included postnatal renal function, frequency of febrile urinary tract infections (UTI), and the need for surgical intervention before the age of 2. This prospective cohort study included fetuses diagnosed with hydronephrosis or other renal abnormalities during second trimester ultrasounds between November 2019 and October 2022. Maternal and child characteristics were compared with data from the Swedish Pregnancy Register. Pre- and postnatal outcomes up to 2 years of age were assessed for fetuses detected antenatally. Outcomes were compared to children diagnosed postnatally within the first 2 years of life and not identified prenatally. Over 3 years, 31 094 second trimester ultrasounds were performed. Hydronephrosis or other renal anomalies were identified in 0.5% (n = 155); approximately 40% resolved by week 32, and seven additional third-trimester detections brought the total number of antenatal cases to 162. By age 2, only 42% had persistent renal abnormalities. A retrospective ICD-10 review identified 45 additional children diagnosed postnatally following symptoms before age 2, yielding an antenatal detection rate of 78.3% (162/207). Baseline demographics were similar between antenatal and postnatal groups and matched those in the Swedish Pregnancy Register. Antenatally detected cases showed diverse anomalies-primarily multicystic dysplastic kidney, duplex kidney, pelviureteric junction obstruction, and vesicoureteral reflux (VUR)-whereas postnatally detected cases were predominantly VUR. Febrile UTI requiring admission occurred in 11.8% of antenatal versus 71.7% of postnatal children (p < 0.0001); surgery rates were similar between groups. The centralized structure of care enabled a comprehensive, population-based cohort with near-complete follow-up. The detection rate of hydronephrosis during second trimester ultrasound is high, reaching ~80%. Given the high rate of spontaneous resolution, the national guideline threshold (APD ≥6 mm) appears to strike a reasonable balance between sensitivity and clinical practicality.
Diagnostic accuracy of kidney ultrasound compared to mercaptoacetyltriglycine-3 scan in paediatric multicystic dysplastic kidney disease.
Multicystic dysplastic kidney disease (MCDK) is a congenital kidney anomaly frequently misdiagnosed as hydronephrosis on antenatal ultrasound. Confirmatory nuclear imaging is seldom available in resource-limited settings. The study aimed to assess the diagnostic accuracy of kidney ultrasound (KUB scan) for detecting paediatric MCDK, using Mercaptoacetyltriglycine-3 scan ([99mTc]Tc-MAG3) differential renal function as the reference standard. A retrospective diagnostic accuracy analysis of consecutive children under 13 years with suspected unilateral MCDK, who underwent both KUB and [99mTc]Tc-MAG3 scans within 6-8 weeks of presentation at Red Cross War Memorial Children's Hospital between January 2014 and December 2023 was done. Diagnosis required characteristic MCDK features on KUB and absent function on [99mTc]Tc-MAG3 scans. Reporting adhered to the STARD guidelines. Of 793 eligible children, the [99mTc]Tc-MAG3 classified 101/101 (100.0%) kidneys as non-functional. The KUB scan accurately identified 97/98 and demonstrated a sensitivity of 99.0% (95% CI: 95.6-99.9%), specificity of 99.9% (95% CI: 99.4-100.0%), PPV of 99.0% (CI: 95.6-99.9%), NPV of 99.9% (99.4-100.0%) and overall accuracy of 99.7% in comparison to [99mTc]Tc-MAG3. Cohen's kappa indicated substantial agreement (0.988), with an AUC of 0.995 (95% CI: 0.983-1.000). Three missing KUB reports were excluded; sensitivity analysis accounting for missing data did not alter these findings. Postnatal kidney ultrasound scan performs excellently in diagnosing paediatric MCDK in the South African context and obviates the need for confirmatory nuclear imaging. This has clinical practice implications for paediatric nephro-urology and supports its use as a primary diagnostic tool both in resource-limited and resource-sufficient settings.
Mesonephric duct anomalies in unilateral multicystic dysplastic kidney: A two-center retrospective study.
Unilateral multicystic dysplastic kidney (UMCDK) is a congenital anomaly detectable already in utero. The affected kidney is non-functioning. While the ureter is typically absent, UMCDK may rarely associate with mesonephric duct (MND) remnants such as ureterocele or ureteral stump. To determine the frequency, clinical implications, and management of ipsilateral MND anomalies in children with UMCDK under comprehensive prenatal and postnatal surveillance. Retrospective analysis of 349 children (0-19 years) with UMCDK, followed by pediatric nephrologists and/or urologists in two tertiary centers between 2005 and 2024, was performed. MND anomalies were classified as: - Type Ia: Orthotopic ureterocele; - Type Ib: Orthotopic ureterocele plus ureteral remnant (stump); - Type II: Ectopic ureteral remnant (stump); - Type III: Complex anomalies involving seminal vesicles/epididymis. Based on medical record and imaging result evaluation, twenty-five patients (7.2 %) with MND anomalies (21 males, 4 females) were identified. Of those, four males (16 %) developed clinical complications (lower urinary tract dysfunction, urinary tract infection (UTI), recurring epididymitis) at different age (3, 8, 12 and 16 years). These symptomatic cases involved Type Ib and Type III anomalies. Median age at diagnosis of MND anomalies was 2 months and median follow-up duration was 10.7 years. All patients had normal glomerular filtration rate (GFR) at the beginning of the observation period, however, two children developed stage 2 chronic kidney disease (CKD 2) until the end of the follow-up. UMCDK resolved spontaneously in 15 patients. MND anomalies regressed below the USG detection threshold only in 3 conservatively managed children (type Ia or Ib). Five patients with MND anomalies required surgical management: 3 children endoscopic incision of ureterocele and 2 children exstirpation of ureterocele with ureteral stump. MND anomalies in UMCDK are uncommon and mostly follow a benign course. Nevertheless, endoscopic or surgical intervention may be required due to late-onset complications, predominantly lower urinary tract dysfunction. Lifelong monitoring is suggested.
Publicações recentes
DICER1-mutated renal neoplasia: A series of 5 cases demonstrating the spectrum of cystic nephroma, Wilms tumor, and anaplastic sarcoma.
Unilateral Multicystic Dysplastic Kidney in a Fetus Associated With Parental Genetic and Environmental Risk Factors: A Case Report.
Genetic Abnormalities and Clinical Management of Fetal Genitourinary System Anomalies in Eastern China.
When childhood anomalies grow up: adult-onset discovery of multicystic dysplastic kidney, a case report.
Outcomes of antenatal hydronephrosis and other renal abnormalities in a population-based cohort.
📚 EuropePMC291 artigos no totalmostrando 197
Unilateral Multicystic Dysplastic Kidney in a Fetus Associated With Parental Genetic and Environmental Risk Factors: A Case Report.
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BJU internationalGFR measurements and ultrasound findings in 154 children with a congenital solitary functioning kidney.
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Proceedings of the National Academy of Sciences of the United States of AmericaUnilateral Multicystic Dysplastic Kidney Management: A National Survey.
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Indian journal of pathology & microbiologyAssociated Anomalies and Complications of Multicystic Dysplastic Kidney.
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Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical geneticsZinner syndrome: a rare diagnosis in infancy.
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BMJ case reportsConcurrent Multicystic Dysplastic Kidney, Posterior Urethral Valves, and Obstructive Ureterocele in a Male Pediatric Patient: A Case Report.
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Pediatric surgery internationalTraumatic Kidney in a Patient With Unilateral Renal Cystic Disease.
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Radiology case reportsUtility of renal scintigraphy in diagnosis of multicystic dysplastic kidney.
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BJU internationalCase Report: Uterine Anomalies in Girls With a Congenital Solitary Functioning Kidney.
Frontiers in pediatricsDilemma after termination of pregnancy due to urogenital fetal anomalies: Discrepancy between prenatal ultrasonographic diagnosis and autopsy.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and ObstetricsMain Physical Features, Echocardiographic and Renal Ultrasonographic Findings of Turner Syndrome in 107 Pediatric Patients.
Molecular syndromologyUltrasound and alternative multimodality imaging of intra-abdominal and pelvic cystic masses in the newborn.
Ultrasound (Leeds, England)Synchronous Development of Hemiscrotal Tissue in the Orthotopic and Ectopic Locations in Association with other Urological Anomalies.
Journal of Indian Association of Pediatric SurgeonsPresence of Cervical Vertebral Anomalies with Concomitant Non-Communicating Hydrocephalus and Multicystic Kidney in a Female Fetus: Where VACTERL-H Meets MURCS.
Fetal and pediatric pathologyA case report with functional characterization of a HNF1B mutation (p.Leu168Pro) causing MODY5.
Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric EndocrinologyExpending the Phenotypic Spectrum of Encephalocraniocutaneous Lipomatosis: About a Prenatal Case With Complete Autopsy.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology SocietyNeonatal multicystic dysplastic kidney with mass effect: A systematic review.
Journal of pediatric urologyMulticystic dysplastic kidney.
American journal of obstetrics and gynecologyThe obstructive index in antenatal unilateral pelviureteric junction obstruction: A novel predictor of the failure of conservative management.
Pediatrics international : official journal of the Japan Pediatric SocietyCongenital Factor VII Deficiency in Association With Bicuspid Aortic Valve and Multicystic Dysplastic Kidney Disease in a Child.
Journal of medical casesClinical Management of Children with a Congenital Solitary Functioning Kidney: Overview and Recommendations.
European urology open scienceUnilateral polycystic kidney disease.
Kidney internationalSegmental multicystic dysplastic kidney: Two case reports.
Pediatrics international : official journal of the Japan Pediatric SocietyReducing Unnecessary Imaging in Children With Multicystic Dysplastic Kidney or Solitary Kidney.
PediatricsComparison between prepubertal and postpubertal patients with obstructed hemivagina and ipsilateral renal anomaly syndrome.
Journal of pediatric urologyNovel CDK10 variants with multicystic dysplastic kidney, left ventricular non-compaction, and a solitary median maxillary central incisor.
Clinical geneticsSpontaneous intraperitoneal renal rupture with urinoma formation in the fetus.
Urology case reportsAssociation of prenatal renal ultrasound abnormalities with pathogenic copy number variants in a large Chinese cohort.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyMinor dysmorphic features in a patient with papillorenal syndrome: A Case Report.
JPMA. The Journal of the Pakistan Medical AssociationHybrid Retroperitoneoscopic Pyeloplasty for Congenital Ureteropelvic Junction Obstruction in Infants Weighing Less than 10 kg.
Journal of laparoendoscopic & advanced surgical techniques. Part APostnatal outcome of prenatally-detected "simple" renal cysts: Are they really simple?
Early human developmentOutcomes of solitary functioning kidneys-renal agenesis is different than multicystic dysplastic kidney disease.
Pediatric nephrology (Berlin, Germany)Posterior Urethral Valve and Prenataly Resolved Multicystic Dysplastic Kidney.
Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)Laparoscopic transposition for crossing vessels (vascular hitch) in pure extrinsic pelvic-ureteric junction obstruction: a successful case report of a 2-year-old infant with horseshoe kidney.
Surgical case reportsPredictors of poor neonatal outcomes in fetuses diagnosed with congenital urinary tract anomalie.
Ginekologia polskaCrossed unfused renal ectopia with pelviureteric junction obstruction associated with nephrolithiasis: a rare troublesome triad managed by robotic surgery.
BMJ case reportsA Newborn with Retrovesical Cysts and an Ipsilateral Multicystic Dysplastic Kidney.
UrologyExpression Pattern of α-Tubulin, Inversin and Its Target Dishevelled-1 and Morphology of Primary Cilia in Normal Human Kidney Development and Diseases.
International journal of molecular sciencesCytogenomic aberrations in isolated multicystic dysplastic kidney in children.
Pediatric researchRenal function in children with a congenital solitary functioning kidney: A systematic review.
Journal of pediatric urologyPathophysiological clinical features of an infant with hypertension secondary to multicystic dysplastic kidney: a case report.
BMC nephrologyRetrospective evaluation of the pediatric multicystic dysplastic kidney patients: experience of two centers from southeastern Turkey.
Turkish journal of medical sciencesVascular hitch for paediatric pelvi-ureteric junction obstruction with crossing vessels: institutional analysis and systematic review with meta-analysis.
BJU internationalPrenatal diagnosis and outcome of unilateral multicystic kidney.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and GynaecologyDiagnosis and Management of Renal Cystic Disease of the Newborn: Core Curriculum 2021.
American journal of kidney diseases : the official journal of the National Kidney FoundationMulticystic Dysplastic Kidney: Prenatal Compensatory Renal Growth Pattern.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in MedicineMulticystic Dysplastic Kidney With Mass Effect in a Neonate Treated With Nephrectomy: Case Report.
UrologyThe Spectrum of Renal Pathologies in Saudi Pediatrics Patients Using Ultrasound.
Pakistan journal of biological sciences : PJBSImaging of fetal cystic kidney disease: multicystic dysplastic kidney versus renal cystic dysplasia.
Pediatric radiologyRenal growth slope in children with congenital and acquired solitary functioning kidneys.
Ultrasonography (Seoul, Korea)Sequence variants in the renin-angiotensin system genes are associated with isolated multicystic dysplastic kidney in children.
Pediatric researchClinical characteristics of children with congenital anomalies of the kidney and urinary tract and predictive factors of chronic kidney disease.
The Turkish journal of pediatricsScreening of renal anomalies in first-degree relatives of children diagnosed with non-syndromic congenital anomalies of kidney and urinary tract.
Clinical and experimental nephrologySeminal Vesicle Cysts With Upper Urinary Tract Abnormalities: A Single-center Case Series of Pediatric Zinner Syndrome.
UrologyRenal cystic diseases during the perinatal and neonatal period.
Journal of neonatal-perinatal medicineHigh Activation of the AKT Pathway in Human Multicystic Renal Dysplasia.
Pathobiology : journal of immunopathology, molecular and cellular biologyTP63-mutation as a cause of prenatal lethal multicystic dysplastic kidneys.
Molecular genetics & genomic medicineA comparison between short- and long-term D-J stent in Anderson-Hynes pyeloplasty for pelvi-ureteric junction obstruction.
Pediatric surgery international"Watch and Wait" Strategy for Multicystic Dysplastic Kidney (MCDK): Status Survey of Perceptions, Attitudes, and Treatment Selection in Chinese Pediatric Urologists and Pediatric Surgeons.
Frontiers in pediatricsUrine hepcidin, netrin-1, neutrophil gelatinase-associated lipocalin and C-C motif chemokine ligand 2 levels in multicystic dysplastic kidney.
Jornal brasileiro de nefrologiaExpansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential.
Cell reports[Kidney Cysts and Cystic Nephropathies in Children - A Consensus Guideline by 10 German Medical Societies].
Klinische PadiatrieOur experience with laparoscopic Anderson-Hynes ureteropyeloplasty.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia PediatricaRetrospective study of the renal function using estimated glomerular filtration rate and congenital anomalies of the kidney-urinary tract in pediatric Turner syndrome.
Congenital anomaliesRobot-assisted laparoscopic pyeloplasty (RALP) in children with complex pelvi-ureteric junction obstruction (PUJO): results of a multicenter European report.
World journal of urologyLigase IV syndrome can present with microcephaly and radial ray anomalies similar to Fanconi anaemia plus fatal kidney malformations.
European journal of medical geneticsWhole-exome sequencing in the evaluation of fetal congenital anomalies of the kidney and urinary tract detected by ultrasonography.
Prenatal diagnosisGuidelines of the Italian Society of Videosurgery in Infancy for the minimally invasive treatment of pediatric nephrectomy and partial nephrectomy.
La Pediatria medica e chirurgica : Medical and surgical pediatricsCortical transit time: understanding utility and pitfalls in children with pelviureteric junction obstruction.
Journal of pediatric urologyThe dilemma of micturating cystourethrogram for congenital solitary kidney.
Pediatric nephrology (Berlin, Germany)Voiding Cystourethrogram in Children With Unilateral Multicystic Dysplastic Kidney: Is It Still necessary?
UrologyMultiple Congenital Anomalies in a Patient with Interstitial 6q26 Deletion.
Molecular syndromologyMulticystic dysplastic kidney - treat each case on its merits.
Journal of pediatric surgeryRenal dysplasia masquerading as a renal mass in a child on hemodialysis.
Hemodialysis international. International Symposium on Home HemodialysisLate occurrence of pelvi-ureteric junction obstruction in renal allograft and live-related kidney donor.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi ArabiaDiagnosis, management, and outcome of obstructed hemivagina and ipsilateral renal agenesis (OHVIRA syndrome): Is there a correlation between MRI findings and outcome?
Clinical imagingRe: A Meta-Analysis of the Incidence and Fate of Contralateral Vesicoureteral Reflux in Unilateral Multicystic Dysplastic Kidney.
The Journal of urologyRe: Evidence-Based Treatment of Multicystic Dysplastic Kidney: A Systematic Review.
The Journal of urology[Pelviureteric junction obstruction and crossing vessels: pro "vascular hitch"].
Aktuelle Urologie[Prenatal diagnosis of multicystic dysplastic kidney: about 18 cases].
The Pan African medical journalLaparoscopic transposition of lower pole crossing vessels in children with extrinsic pelvi-ureteric junction obstruction: a worthy alternative to dismembered pyeloplasty.
Journal of biological regulators and homeostatic agentsClinical course of a pediatric series of multicystic dysplastic kidney.
Journal of biological regulators and homeostatic agentsIntroduction to the special issue: "Focus on pediatric nephrology".
Journal of biological regulators and homeostatic agentsAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Unilateral Multicystic Dysplastic Kidney in a Fetus Associated With Parental Genetic and Environmental Risk Factors: A Case Report.
- Genetic Abnormalities and Clinical Management of Fetal Genitourinary System Anomalies in Eastern China.
- Outcomes of antenatal hydronephrosis and other renal abnormalities in a population-based cohort.
- Diagnostic accuracy of kidney ultrasound compared to mercaptoacetyltriglycine-3 scan in paediatric multicystic dysplastic kidney disease.
- Mesonephric duct anomalies in unilateral multicystic dysplastic kidney: A two-center retrospective study.
- DICER1-mutated renal neoplasia: A series of 5 cases demonstrating the spectrum of cystic nephroma, Wilms tumor, and anaplastic sarcoma.
- When childhood anomalies grow up: adult-onset discovery of multicystic dysplastic kidney, a case report.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:1851(Orphanet)
- MONDO:0015988(MONDO)
- GARD:18748(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
- Q6934642(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
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