Somatic mutational landscape in von Hippel-Lindau familial hemangioblastoma.

[Calcinosis cutis in a hemodialysis patient with Von Hippel-Lindau disease].

Neurogenetic tumor syndromes: The current landscape of workup and treatment.

"I don't think I even thought of myself" A mixed-methods study of family experiences of trio germline whole genome sequencing in newly diagnosed childhood cancer.

Bilateral multifocal renal neuroendocrine carcinoma with synchronous pancreatic neuroendocrine carcinoma and adrenal lesion.

Pancreatic Involvement in von Hippel Lindau Disease: A Single-Center Experience.

Cancer predisposition syndromes: an imaging review.

5' UTR length regulates alternative N-terminal protein isoform production in health and disease.

[A Family case of von Hippel-Lindau syndrome].

Persistent Hypercalcemia: Diagnostic Complexity With Multiglandular Hyperparathyroidism, Renal Cell Carcinoma, and Hereditary Tumor Features.

Hereditary Renal Cancer Syndromes: Clinicopathologic Features and Correlation With Tumors Harboring Somatic Mutations.

Exploring the Illness Experience of Patients with Central Nervous System Hemangioblastomas in Von Hippel-Lindau Disease: A Qualitative Study.

Bilateral pheochromocytomas with locally advanced right adrenal tumor extending into the inferior vena cava in a suspected Von Hippel-Lindau syndrome: A case report.

First-in-class HIF-2α therapy in genitourinary oncology: Belzutifan from von Hippel-Lindau disease to advanced renal cell carcinoma.

Whole-Genome Landscape of Retinal Hemangioblastomas.

Expanding the clinical tumor phenotype of the EPAS1-asssociated tumor syndrome.

Hereditary renal cell carcinoma surveillance protocols: a review of the literature and proposed recommendations.

Distinct genomic, microenvironmental, and nephron signatures in VHL kidney cysts and tumors.

The European medicines agency review of belzutifan (Welireg) for the treatment of adult patients with von Hippel-Lindau disease-associated tumors.

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review.

Role of Targeted Therapy in the Management of von Hippel-Lindau Disease-Associated Renal Cell Carcinoma: A Single-Proportion Meta-Analysis.

[Chinese expert consensus for the diagnosis and treatment of von Hippel-Lindau syndrome (2025 edition)].

Precision Care for Hereditary Urologic Cancers: Genetic Testing, Counseling, Surveillance, and Therapeutic Implications.

Integrating whole-exome sequencing and scRNA-seq reveal the characteristic in one clear cell renal cell carcinoma sample arising in the setting of VHL disease.

Anesthetic Management of a Cesarean Section in a Parturient With Von Hippel-Lindau Disease.

Belzutifan for Ocular Tumors in Patients with von Hippel-Lindau Disease.

Prognostic relevance of MIB-1 labeling index in VHL-associated and sporadic spinal hemangioblastomas: a subgroup analysis from a multicentric study.

Percutaneous Cryoablation With Lipiodol Marking for Hereditary Renal Cell Carcinomas: Cancer Control and Renal Functional Outcomes.

Dysregulation of the ubiquitin-proteasome system in von Hippel-Lindau syndrome: molecular insights and clinical perspectives.

From surgery to systemic therapy in von Hippel-Lindau disease: insights from extended follow-up of LITESPARK-004.

From surgery to systemic therapy: long-term lessons of belzutifan in von Hippel-Lindau disease.

Adrenergic Storm with Obstructive Hydrocephalus: Atypical Neurological Presentation of Von Hippel-Lindau Disease with Bilateral Pheochromocytoma in an Adolescent.

Near-infrared carbon dots enable ultra-sensitive fluorometric detection of belzutifan: a novel approach for real-time therapeutic drug monitoring in cancer treatment.

Familial Von Hippel-Lindau Disease: A Case Series of Cerebral Hemangioblastomas with MRI, Histopathological, and Genetic Correlations.

Von Hippel-Lindau Disease-Associated Endolymphatic Sac Tumours: Seven Cases and Genotype-Phenotype Features.

Genetic Testing and Counselling for Hereditary Renal Carcinoma: What Do Clinicians Need to Know?

Clinical challenges of cancer predisposition syndromes with pediatric central nervous system tumors: a single-center study.

Re: W. Marston Linehan, Cathy Anne Pinto, Yanfang Liu, et al. Longitudinal Evaluation of Clear-cell Renal Cell Carcinoma in von Hippel-Lindau Disease. Eur Urol 2025;88:56-63.

The truth behind multiple neuroendocrine tumors: Von Hippel-Lindau syndrome and its diagnostic challenges-A case report and literature review.

Stereotactic radiosurgery as adjuvant or salvage treatment for sporadic hemangioblastomas: A multi-center international study.

Intra- and inter-tumoural heterogeneity in von Hippel-Lindau disease-related renal cancer: a multimodal data study protocol.

Long-term HIF-2α inhibition in von Hippel-Lindau disease: insights from LITESPARK-004.

Multigenerational VHL family characterized by pathogenic germline ELOC variant: Response to belzutifan.

Types of pancreatic lesions and the mutational landscape of the VHL gene in patients with von Hippel-Lindau disease.

Identification of a VHL germline deletion in a family with Von Hippel-Lindau syndrome using MLPA-NGS.

All-in-One Case: Comprehensive Detection of VHL Syndrome With 68 Ga-DOTATATE PET/CT.

Belzutifan for patients with Von Hippel-Lindau (VHL) disease-associated heterogeneous tumors - a retrospective single center analysis.

BRCA1-, BRCA2-, and PALB2-related Fanconi anemia: Scope to expand disease phenotypic features and predict breast cancer risk in heterozygotes.

[Cystic-solid transformation of the pancreas and kidneys due to von Hippel-Lindau disease].

Canine Hemangioblastoma: Case Series and Literature Review.

Computed tomography-guided radiofrequency ablation of pheochromocytomas in a small case series with von Hippel-Lindau disease: treatment safety and outcomes.

Multisystemic Presentation of Von Hippel-Lindau Disease Revealed by Pheochromocytoma and Takotsubo Syndrome.

First-in-class oral hypoxia-inducible factor 2α in von Hippel-Lindau disease: a new era of targeted therapy.

Updated 2025 French guidelines for renal cell carcinoma.

HIFα isoform specific activities drive cell-type specificity of VHL-associated oncogenesis.

Gross total resection is associated with improvement and prognosis even in von Hippel-Lindau disease-related hemangioblastomas: Nationwide registry in Japan.

Collision of Retinitis Pigmentosa and Von-Hippel Lindau Disease.

Laparoscopic Left Hepatectomy for Slowly Progressing Primary Hepatic Carcinosarcoma Associated With Von Hippel-Lindau Disease.

Unraveling the impact of VHL exon 2 mutations in erythrocytosis or von Hippel-Lindau disease identified RNA-binding proteins involved in VHL splicing.

Role of PPV in Advanced Retinal Hemangioblastoma-A Systematic Review.

Quantitative analysis of the anti-VEGF effect for retinal capillary hemangiomas and vasoproliferative tumors.

The gradual expansion of multiple intramedullary metastatic renal cell carcinoma in a patient with von Hippel-Lindau disease with multiple intramedullary hemangioblastomas: illustrative case.

Mathematical modeling and simulation of tumor-induced angiogenesis in retinal hemangioblastoma.

Pancreatic Hemangioblastoma in a Patient with von Hippel-Lindau Disease: A Case Report.

The safety profile of belzutifan in renal tumors: real-world data from a tertiary academic center.

Pancreatic Involvement by Mixed Serous Neuroendocrine Neoplasm Detected by Endosonography With Fine-Needle Tissue Acquisition in Von Hippel-Lindau Disease.

Impact of Belzutifan on Pancreatic Cystic Lesions and Neuroendocrine Tumors in Patients With Von Hippel-Lindau Disease.

Presentation, management, and clinical outcomes of von Hippel-Lindau syndrome.

Synchronous giant bilateral renal tumors as initial presentation of Von Hippel-Lindau disease: Sequential surgical management and transition to renal replacement therapy.

Unclassified Renal Cell Carcinoma with Reverse Polarity and Pathogenic von Hippel-Lindau Mutation in a Congenital Renal Malformation.

Belzutifan-Associated Hypoxia: A Review of the Novel Therapeutic, Proposed Mechanisms of Hypoxia, and Management Recommendations.

The impact of surgery on patients with Von Hippel-Lindau-associated tumors: an international patient survey.

Quantification of Belzutifan in Biological Samples: LC-MS/MS Method Validation and Pharmacokinetic Study in Rats.

Proteomic characterization of the pseudocapsule of clear cell renal cell carcinoma in VHL disease reveals a distinct microenvironment at the tumor boundary zone.

Von Hippel-Lindau Disease.

Tumor-to-Tumor Metastasis in a Patient With Hemangioblastoma Unrelated to von Hippel-Lindau Disease: A Case Report and Review of the Literature.

Clinical, Pathologic, and Genetic Correlates of Nuclear Grade in von Hippel-Lindau-associated Renal Cell Carcinoma.

Detection of VHL variant on multigene panel testing for hereditary breast cancer: Implications for genetic counselling.

Incidental Discovery of Synchronous Ileal Neuroendocrine Tumors at Fluorodopa PET/CT in a Patient With Bilateral Pheochromocytoma.

PMDA regulatory update on approval and revision of the precautions for use of anticancer drugs in Japan; nivolumab plus ipilimumab for hepatocellular carcinoma, fedratinib for myelofibrosis, talquetamab for multiple myeloma, and belzutifan for tumors associated with von Hippel-Lindau disease and renal cell carcinoma.

Anesthetic challenges in a pregnant patient with Von Hippel-Lindau disease: A case report.

Case report: Nephrotic syndrome induced by Lenvatinib treatment in a patient with von Hippel-Lindau syndrome.

Papillary endolymphatic sac tumor: Case report with clinical study and therapeutic management.

Real-world challenges and considerations in treating von Hippel-Lindau disease with HIF-2α inhibitors - Authors' reply.

Real-world challenges and considerations in treating von Hippel-Lindau disease with HIF-2α inhibitors.

Analysis of BRCA1, BRCA2 and PALB2 related Fanconi anemia identifies scope to expand disease phenotypic features and predict breast cancer risk in heterozygotes.

Bilateral Pheochromocytoma in a Child Revealing Von Hippel-Lindau Disease.

Von Hippel-Lindau disease caused obstructive jaundice.

Outcomes After Stereotactic Radiosurgery for Intracranial Hemangioblastoma in Von Hippel-Lindau Disease and Sporadic Cases: An International Multicenter Study.

Corrigendum to "Von Hippel-Lindau Disease : A Comprehensive Review of Diagnosis, Genetics, Clinical Challenges, and Surveillance" by Jung et al. (J Korean Neurosurg Soc 68 : 338-349, 2025).

When is belzutifan the right option for von Hippel-Lindau disease-associated hemangioblastomas?-a critical review of LITESPARK-004 results.

Leptomeningeal hemangioblastoma: illustrative case.

A real-world pharmacovigilance study of belzutifan in renal cell carcinoma and von Hippel-Lindau disease: insights from the FDA adverse event reporting system database.

Genotype-phenotype correlation in Iranian retinal hemangioblastoma patients and genetic diagnosis algorithm for Von Hippel-Lindau disease.

Bilateral simultaneous laparoscopic clipless adrenal-sparing surgery for pheochromocytoma in a pediatric patient: A case report.

CRISPR/Cas9-mediated editing of VHL in induced pluripotent stem cells: A model for early cell fate in von Hippel-Lindau syndrome.

Pseudohypoxia caused by germline genetic alterations in the VHL gene is associated with increased diabetes and cardiovascular risk: a UK biobank study.

Unilateral Pheochromocytoma in Von Hippel-Lindau Syndrome Revealed by a Hemangioblastoma.

Dual Inhibition of HIF-1α and HIF-2α as a Promising Treatment for VHL-Associated Hemangioblastomas: A Pilot Study Using Patient-Derived Primary Cell Cultures.

Bilateral Pheochromocytoma with a Novel Pathogenic Variant in the MAX gene: A Case Report.

Spinal Hemangioblastoma: The Role of Imaging Characteristics in Preoperative Diagnosis and Surgical Planning.

Fibroblast growth factor receptor expression in hemangioblastomas: A novel therapeutic target.

Fatal intracranial haemorrhage shortly after belzutifan initiation in von Hippel-Lindau (VHL) disease-associated haemangioblastoma.

When Evidence Falls Short-Belzutifan for Treating Tumours Associated with von Hippel-Lindau Disease: An External Assessment Group Perspective on a NICE Single Technology Appraisal.

Disease Monitoring and Treatment Patterns of von Hippel-Lindau Disease-Associated Renal Cell Carcinoma in the United States.

Pediatric and adolescent von Hippel-Lindau disease: tumor profiles, genotype-phenotype correlation and comparison with adults.

Longitudinal Evaluation of Clear-cell Renal Cell Carcinoma in von Hippel-Lindau Disease.

Genetics and current research models of Mendelian tumor predisposition syndromes with ocular involvement.

[Clinical characterization in patients with neurocutaneous syndrome].

Novel OCT Angiography Features, von Hippel-Lindau Disease Association, and Genetic Characterization of Juxtapapillary Retinal Capillary Hemangiomas.

Update on Surveillance in Von Hippel-Lindau Disease.

Belzutifan for von Hippel-Lindau disease-associated renal cell carcinoma and other neoplasms (LITESPARK-004): 50 months follow-up from a single-arm, phase 2 study.

Belzutifan in von Hippel-Lindau disease.

Retinal vascular proliferation with fibrotic regression in von Hippel-Lindau disease.

A Corticotropin-Secreting Adenoma in the Setting of von Hippel-Lindau Disease.

Genotype-specific neoplastic risk profiles in patients with VHL disease.

Emerging Paradigms in Genitourinary Cancers: Integrating Molecular Imaging, Hypoxia-Inducible Factor-Targeted Therapies, and Antibody-Drug Conjugates in Renal Cell and Urothelial Carcinomas.

Bilateral papillary cystadenoma of the broad ligament: a manifestation of Von Hippel-Lindau disease: a case report.

Urinary leak after partial nephrectomy: Insights from a cohort with hereditary, multifocal, and reoperative cases.

Pancreatic neuroendocrine neoplasms (pNENs): Genetic and environmental biomarkers for risk of occurrence and prognosis.

Factors that predict progression of von Hippel-Lindau disease-related malignancy: a longitudinal cohort study.

Very early-onset symptomatic CNS haemangioblastoma in Von Hippel-Lindau disease.

Mosaic Form of von Hippel-Lindau Syndrome: Case Report and Literature Review.

Resection of a Cervical Spine Hemangioblastoma in Von Hippel-Lindau Disease: 2-Dimensional Operative Video.

Von Hippel-Lindau Disease : A Comprehensive Review of Diagnosis, Genetics, Clinical Challenges, and Surveillance.

Pancreatic Serous Neoplasm and Metastatic Clear Cell Renal Cell Carcinoma: Diagnostic Pitfalls Resolvable by a Panel of Immunohistochemical Stains to Include PAX8 and CK7 But Not CAIX.

Stereotactic radiosurgery in the management of central nervous system hemangioblastomas: a systematic review and meta-analysis.

Characterization of the Pheochromocytoma-Predominant Subgroup of von Hippel-Lindau Disease.

Recanalization and interventional stenting of a closed ductus arteriosus in pulmonary hypertension associated with von Hippel-Lindau disease: a case report.

"Incidentally" discovered Von Hippel Lindau disease: an emerging clinical phenotype.

Von Hippel-Lindau syndrome with bilateral renal and an interaortocaval mass.

Von Hippel-Lindau syndrome: clinical features, genetic foundations, and management strategies.

First Single-Centre Experience with the Novel HIF-α Inhibitor Belzutifan in Switzerland.

Vasoproliferative Retinal Tumors: Manifestations, Management, and Outcomes in a Case Series.

Delivering Trio Germline Whole Genome Sequencing to Patients Newly Diagnosed With Childhood Cancer: Healthcare Professionals' Perspectives of the PREDICT Study.

Local tumor control and neurological outcomes after surgery for spinal hemangioblastomas in sporadic and von Hippel-Lindau disease: A multicenter study.

Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease.

[Retinal vasoproliferative tumor (retinal reactive astrocytic tumor)].

A New Era of Management of Von Hippel-Lindau Disease-Associated Tumors With Belzutifan.

Morphology of Retinal Hemangioblastoma in von Hippel-Lindau Disease Revealed by Optical Coherence Tomography Angiography.

Laparoscopic Partial Nephrectomy for Multiple Complex Renal Masses in a Patient With Von Hippel-Lindau Syndrome: A Case Report.

Therapeutic Dilemma of a Juxtapapillary Retinal Capillary Hemangioma.

Case report: Endolymphatic sac tumor with blurred vision.

Relationship between ZHX2 Expression and VHL Gene Alteration in VHL-associated and Sporadic Hemangioblastomas of the Central Nervous System.

Long-term surgical outcomes and prognosis of cervical spinal hemangioblastomas.

Evaluation of Tumor-Infiltrating Leukocytes in Endolymphatic Sac Tumor.

Oral Herpes Simplex Virus Mimicking Tongue Squamous cell Carcinoma in Von Hippel-Lindau Patient: A Case Image.

New Developments in VHL-Associated Neuroendocrine Neoplasms.

Belzutifan as the Primary Treatment of Bilateral Juxtapapillary Retinal Hemangioblastoma in a Patient With Von Hippel-Lindau Disease.

Pheochromocytoma in von Hippel-Lindau Disease: Clinical Features and Comparison With Sporadic Pheochromocytoma.

Genetic syndromes associated with pancreatic neuroendocrine neoplasms and imaging diagnostic strategies.

Is the TriNetX Database a Good Tool for Investigation of Real-World Management of Von Hippel-Lindau?

[Diagnostic and therapeutic perspectives in RASopathies].

[Stereotactic radiotherapy of spinal hemangioblastoma].

Case study of a potential West Polynesian variant of von Hippel-Lindau disease.

Generation of TWO iPSC lines (CRICKi009-A; CRICKi010-A) from patients with type 1 von Hippel-Lindau (VHL) and histopathologically confirmed renal cell carcinoma (RCC).

Surgical Management and Prognostic Factors for Endolymphatic Sac Tumor: A Single-Institute Experience with a Systematic Review.

Von Hippel-Lindau disease with ocular and multiple systemic findings.

Spinal cord hemangioblastomas in von Hippel-Lindau disease.

Current views on the role of HIF-2α in the pathogenesis and syndromic presentation of pheochromocytoma and paraganglioma.

Comparative analysis of stereotactic radiosurgery outcomes for supratentorial hemangioblastomas in von hippel-lindau disease and sporadic cases: A multi-center international study.

Pediatric patients with von Hippel-Lindau and hemangioblastomas treated successfully with belzutifan.

Multisystem diseases in the abdomen and pelvis: imaging manifestations and diagnostic roles of cross-sectional imaging.

Follow-up report on pulmonary mucosa-associated lymphoma in a patient with von Hippel-Lindau disease.

Genotype-phenotype correlation of ocular von Hippel-Lindau disease in Koreans.

Familial and early recurrent pheochromocytoma in a child with a novel in-frame duplication variant of VHL.

Unique properties of clinical manifestation and magnetic resonance imaging for differential diagnosis of optic nerve hemangioblastoma.

Application of carbonic anhydrase IX in sporadic hemangioblastoma of the central nervous system and hemangioblastoma associated with von Hippel-Lindau disease.

Phenotypic and Genotypic Features of a Chinese Cohort with Retinal Hemangioblastoma.

Total loss of VHL gene function impairs neuroendocrine cancer cell fitness due to excessive HIF2α activity.

A novel pathogenic germline chromosome 3 inversion in von Hippel-Lindau disease.

Hereditary Pheochromocytoma as a Main Manifestation of von Hippel Lindau Disease (vHL) in Childhood - A Long-term Follow-up of 5 Patients with vHL from One Family.

Belzutifan Efficacy and Tolerability in Patients with Sporadic Metastatic Clear Cell Renal Cell Carcinoma.

Belzutifan for patients with von Hippel-Lindau disease-associated CNS haemangioblastomas (LITESPARK-004): a multicentre, single-arm, phase 2 study.

Genetics, Pathophysiology, and Current Challenges in Von Hippel-Lindau Disease Therapeutics.

Belzutifan in Individuals with von Hippel-Lindau Retinal Hemangioblastomas: Institutional Experience and Review of the Literature.

Advances in Molecular Mechanisms of Kidney Disease: Integrating Renal Tumorigenesis of Hereditary Cancer Syndrome.

Clear Cell Renal Cell Carcinoma: Characterizing the Phenotype of Von Hippel-Lindau Mutation Using MRI.

Endolymphatic Sac Tumors Associated With von Hippel-Lindau: A Case Report Highlighting Opportunity for Novel Orphan Drug Therapy.

Unusual Presentation of Von Hippel-Lindau Syndrome With Gastric Variceal Bleeding.

The genetic differences between types 1 and 2 in von Hippel-Lindau syndrome: comprehensive meta-analysis.

Understanding Adult Central Nervous System Hemangioblastomas: A Systematic Review.

The rare diagnosis of Von Hippel-Lindau disease in a 29-year-old patient.

Innovative solutions? Belzutifan therapy for hemangioblastomas in Von Hippel-Lindau disease: A systematic review and single-arm meta-analysis.

Clinical T1a Renal Cell Carcinoma with Solitary Diaphragmatic Metastasis in a Patient with von Hippel-Lindau Disease.

Neurosurgical Implications of Targeting Hypoxia-Inducible Factor 2α in Hemangioblastomas with Belzutifan.

Trigeminal nerve hemangioblastoma in the setting of undiagnosed von Hippel-Lindau disease: illustrative case.

Evaluating the Urinary Exosome microRNA Profile of von Hippel Lindau Syndrome Patients with Clear Cell Renal Cell Carcinoma.

Optic nerve and chiasm hemangioblastomas in von Hippel-Lindau disease: report of 12 cases and review of the literature.

Portal Venous Thrombosis after Percutaneous Cryoablation for Renal Cell Carcinoma.

Single Stage Bilateral Adrenalectomy (Cortical-Sparing) and Pancreatectomy (Corpus-Sparing) in a Patient with Von Hippel-Lindau Disease.

Optical Coherence Tomography Angiography-Navigated Laser Photocoagulation of Retinal Hemangioblastomas in Patients With von Hippel-Lindau Disease.

von Hippel-Lindau Syndrome and Secondary Hypertension: A Case Report.

Cauda equina myxopapillary ependymoma in von Hippel-Lindau disease: A case report.

Characterization of spinal hemangioblastomas in patients with and without von Hippel-Lindau, and YAP expression.

Comprehensive treatment of von Hippel-Lindau disease: A case report.