Raras
Buscar doenças, sintomas, genes...
Gastrosquise
ORPHA:2368CID-10 · Q79.3CID-11 · LB02OMIM 230750DOENÇA RARA

A gastrosquise é quando órgãos internos do feto (o bebê na barriga da mãe) saem do abdômen (da barriga) e ficam para fora, sem nenhuma bolsa protetora que os cubra. Isso acontece no lado direito da base do umbigo. É causada por um problema no desenvolvimento do embrião, e é muito raro que o bebê apresente outros defeitos de formação ao mesmo tempo.

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Introdução

O que você precisa saber de cara

📋

A gastrosquise é quando órgãos internos do feto (o bebê na barriga da mãe) saem do abdômen (da barriga) e ficam para fora, sem nenhuma bolsa protetora que os cubra. Isso acontece no lado direito da base do umbigo. É causada por um problema no desenvolvimento do embrião, e é muito raro que o bebê apresente outros defeitos de formação ao mesmo tempo.

Pesquisas ativas
7 ensaios
50 total registrados no ClinicalTrials.gov
Publicações científicas
2.936 artigos
Último publicado: 2026 Apr 9

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-5 / 10 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Europe
Início
Antenatal
🏥
SUS: Cobertura mínimaScore: 15%
CID-10: Q79.3
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (5)
0202010503
Cariótipo — bandas G, Q ou Rgenetic_test
0202010600
Pesquisa de microdeleções/microduplicações por FISHlab_test
0202010694
Sequenciamento completo do exoma (WES)rehabilitation
0202010260
Dosagem de alfa-fetoproteína
0301070040
Atendimento em reabilitação — doenças raras
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫃
Digestivo
6 sintomas
📏
Crescimento
1 sintomas
🦴
Ossos e articulações
1 sintomas

+ 8 sintomas em outras categorias

Características mais comuns

90%prev.
Gastrosquise
Muito frequente (99-80%)
55%prev.
Morfologia anormal do sistema gastrointestinal fetal
Frequente (79-30%)
55%prev.
Concentração materna elevada de alfa-fetoproteína circulante
55%prev.
Anormalidade do cordão umbilical
Frequente (79-30%)
55%prev.
Retardo do crescimento intrauterino
Frequente (79-30%)
17%prev.
Perfuração intestinal
Ocasional (29-5%)
16sintomas
Muito frequente (1)
Frequente (4)
Ocasional (8)
Sem dados (3)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 16 características clínicas mais associadas, ordenadas por frequência.

GastrosquiseGastroschisis
Muito frequente (99-80%)90%
Morfologia anormal do sistema gastrointestinal fetalAbnormal fetal gastrointestinal system morphology
Frequente (79-30%)55%
Concentração materna elevada de alfa-fetoproteína circulanteElevated maternal circulating alpha-fetoprotein concentration
Frequente55%
Anormalidade do cordão umbilicalAbnormality of the umbilical cord
Frequente (79-30%)55%
Retardo do crescimento intrauterinoIntrauterine growth retardation
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico2.936PubMed
Últimos 10 anos200publicações
Pico2025103 papers
Linha do tempo
2026Hoje · 2026🧪 2001Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado2
2Fase 21
1Fase 11
·Pré-clínico16
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Gastrosquise

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

5 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

50 ensaios clínicos encontrados, 7 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
1.099 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 1.099

#1

A survey of Ugandan skilled birth attendants regarding beliefs and management of gastroschisis.

BMJ global health2026 Mar 09

Gastroschisis mortality is disproportionately high in Africa due in part to delayed presentation and limited surgical capacity. Skilled birth attendants (SBAs) are often the first to encounter these babies and can be an important part of their stabilisation. We assessed baseline Ugandan SBA knowledge of gastroschisis and interest in a training course. Southwestern Ugandan SBAs were surveyed regarding practice patterns, common beliefs and training course interest. Data were analysed with descriptive statistics. We recruited 121 participants (70 midwives, 51 nurses). Most had a certificate or diploma (n=117, 97%) and 85% had more than 3 years of experience (n=103). Eighty-seven (72%) SBAs had cared for babies with gastroschisis. Most reported that communities stigmatised families (n=67, 55%), saw the child as cursed (n=74, 61%), blamed the mother (n=69, 57%) and advised parents to kill (n=30, 24%) or abandon the child (n=55, 45%). Barriers to families seeking care included healthcare mistrust (n=3, 2%), hopelessness (n=37, 31%), lack of knowledge (n=51, 42%), transportation difficulties (n=54, 45%) and fear of impoverishment (n=84, 69%). Most SBAs were unsure of the cause of gastroschisis and only 6% (n=8) recognised fetal vascular interruption as the cause. While 57% (n=69) prioritised intestinal coverage, only 7% (n=9) and 5% (n=6) would place a nasogastric tube or fast the baby. Three midwives encouraged immediate breastfeeding. Antibiotics (n=22, 18%) and fluid resuscitation (n=19, 16%) were sometimes recommended. Most participants (n=119, 98%) desired a course on gastroschisis management, but 41% (n=50) reported time constraints as a barrier. Southwestern Ugandan SBAs encounter gastroschisis babies, have limited training in its management and desire a training course. Engaging SBAs into a task-sharing role on delivery is a promising next step. Additional studies will be needed to determine if this can improve gastroschisis survival by reducing delays in care and improving community awareness.

#2

Epidemiological profile of pregnant women and perinatal outcomes of newborns with gastroschisis from a single reference center in Northeastern Brazil.

Ceska gynekologie2026

To determine the maternal epidemiological profile and perinatal outcomes of fetuses with gastroschisis at a reference center in Northeastern Brazil. A retrospective cohort study was conducted between January 2014 and December 2022 using medical records. Inclusion criteria comprised of pregnancies ≥ 24 weeks, with a prenatal diagnosis of gastroschisis confirmed in the postnatal period. During the study period, 1,773 newborns with congenital anomalies were born at the service center, 50 were identified as having gastroschisis and four cases were excluded. Prevalence of gastroschisis was 11.5/10,000. Regarding the maternal sociodemographic profile, the mean age was 21 years, 38/46 (83%) were mixed, 34/46 (74%) had a partner, and 32/46 (70%) had high school education. Regarding associated maternal diseases, only 6/46 (13%) had hypertension, none had pre-existing diabetes mellitus, and 4/46 (8.7%) developed gestational diabetes mellitus. As for gastroschisis type, 33/46 (71%) were classified as simple, 11/46 (23.9%) as complex and 2/46 (4.4%) had no information. In 36/46 newborns with gastroschisis, primary closure was performed in the first surgery. The mean time of use of mechanical ventilation was 13 days, the mean time interval between surgery and ambient air was 8 days, the mean time of use of parenteral nutrition was 35 days, and the mean length of stay in the neonatal intensive care unit (NICU) was 39 days. Clinical complications in newborns with gastroschisis included neonatal infection in 35/46 (76%), blood transfusion in 33/46 (72%), hydroelectrolytic disorders and sepsis in 29/46 (63%), and cholestasis and fungal infection/sepsis in 8/46 (17%). Neonatal death occurred in 16/46 (34.8%). Newborns with gastroschisis presented high rates of surgery with primary closure, blood transfusion and neonatal infection. Furthermore, we identified prolonged use of parenteral nutrition, long stay in the NICU, and prolonged use of antibiotic therapy.

#3

Clinical Presentation and Diagnostic Challenges of Congenital Thoracoabdominal Wall Defects in Dogs: Insights from a Case Series and Literature Synthesis.

Animals : an open access journal from MDPI2026 Feb 24

Congenital thoracoabdominal wall defects in dogs are uncommon and challenging to classify due to their overlapping anatomical and developmental features. This study analyzes three original canine cases alongside 17 published cases to clarify the relationships among Cantrell syndrome (CS), amniotic band syndrome (ABS), and body stalk anomaly (BSA). All of the original cases exhibited thoracoabdominal involvement with variations in umbilical cord morphology and associated anomalies. A comparative analysis revealed that these conditions form a syndromic continuum rather than distinct entities, influenced by the timing and mechanism of embryonic disruption. Early developmental insults were associated with multisystem malformations resembling CS or BSA, whereas later vascular disruptions produced more localized defects, such as gastroschisis. Umbilical cord morphology emerged as a key diagnostic discriminator across cases. Based on these findings, we developed an anatomically driven diagnostic decision tree to support clinical evaluation when information is incomplete. This study emphasizes the importance of integrating embryologic context with anatomical assessment and identifies significant gaps in molecular and genetic data. A developmental continuum model offers a more flexible, clinically meaningful framework for diagnosing congenital body wall defects in dogs.

#4

Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie2026 Mar 12

Previous studies exploring long-term outcomes of patients with omphalocele and gastroschisis suggest an ongoing burden of gastrointestinal symptoms but also highlight substantial heterogeneity in methodology and outcomes measurement, limiting comparability. Therefore, the aim of this study was to systematically evaluate patient-reported long-term gastrointestinal symptoms, using a validated questionnaire, and compare the scores to those of healthy controls.All children treated for omphalocele and gastroschisis between 1999 and 2022 were invited to complete the Pediatric Quality of Life Inventory GI Module, consisting of twelve gastrointestinal domains. Parent proxy-reports or child self-reports were sent by mail, appropriate for the participants' age. The scores were compared with a predefined American healthy cohort (n = 513). Significance threshold was p < 0.004 (Bonferroni-corrected).In total, 45/131 (34.4%) respondents completed the questionnaire, of whom 20 had omphalocele (50.0% male, median age 10.4 years [IQR: 6.4-16.4]), and 25 had gastroschisis (56.0% male, median age 9.9 years [IQR: 6.2-16.8]). Omphalocele patients reported a similar mean total score (86.5 [ ± 15.9] vs. 88.6 [ ± 12.9], d = 0.15, p = 0.566) and similar domain scores (d < 0.35, p > 0.01) compared with healthy controls. Gastroschisis patients also reported a similar mean total score compared with healthy controls (84.9 [SD ± 10.9], d = 0.31, p = 0.112). However, they scored worse on the domains "gas and bloating" (d = 0.78, p = 0.001), "diarrhea" (d = 0.74, p = 0.002), and "constipation" (d = 0.51, p = 0.026).Omphalocele patients reported a low burden of long-term gastrointestinal symptoms, indicating that routine follow-up may not be required. In contrast, gastroschisis patients reported a higher prevalence of gas and bloating, diarrhea, and constipation compared with healthy controls, highlighting the importance of early recognition and targeted management of these symptoms.

#5

A Pilot Study to Advance Task-Sharing of Gastroschisis Management in Uganda.

Annals of global health2026

Introduction: Gastroschisis mortality in Africa is high partly due to delays in care. In Uganda, skilled birth attendants (SBAs) are the first point-of-contact for most babies, and with proper training, may be willing to participate in surgical task-sharing. Objective: Empower Ugandan skilled birth attendants with the knowledge and practical skills needed to care for babies with gastroschisis. Methods: Ugandan SBAs completed a one-day gastroschisis course, and resident physicians also requested to participate. A pre- and post-course test was administered to assess gastroschisis knowledge and confidence. Findings: A total of 69 SBAs (44 midwives, 25 nurses) and 17 residents participated. Participants were predominantly female (n = 64, 74%) with a median of 9 years of work experience. There was significant knowledge increase from pre- to post-course regarding differentiating gastroschisis from omphalocele (SBA 39% to 70%, p < 0.001; resident 48% to 77%, p < 0.001), gastroschisis incidence and outcomes (SBA 56% to 87%, p < 0.001; resident 65% to 89%, p < 0.001), risk factors (SBA 66% to 89%, p < 0.001; resident 67% to 86%, p < 0.0026), treatment (SBA 57% to 84%, p < 0.001; resident 63% to 79%, p < 0.001), and importance of community education (SBA 54% to 59%, p < 0.006; resident 56% to 65%, p < 0.0413). Only SBAs showed a significant increase in prenatal diagnosis (74% to 88%, p < 0.001). There was a significant boost in SBA clinical management confidence from 39% to 88%. Conclusion: A one-day training course can enable Ugandan SBAs to serve as task-sharers for babies with gastroschisis. While residents benefited, a future course should be developed for their learning needs. Continuing education is needed to ensure knowledge retention and clinical preparedness. Assessment of gastroschisis outcomes is necessary to determine if involving SBAs can improve survival.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC1.840 artigos no totalmostrando 196

2025

[Prevalence and mortality factors in initial hospitalization for gastroschisis].

Andes pediatrica : revista Chilena de pediatria
2026

Epidemiological profile of pregnant women and perinatal outcomes of newborns with gastroschisis from a single reference center in Northeastern Brazil.

Ceska gynekologie
2026

Clinical Presentation and Diagnostic Challenges of Congenital Thoracoabdominal Wall Defects in Dogs: Insights from a Case Series and Literature Synthesis.

Animals : an open access journal from MDPI
2026

Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie
2026

A survey of Ugandan skilled birth attendants regarding beliefs and management of gastroschisis.

BMJ global health
2026

A Pilot Study to Advance Task-Sharing of Gastroschisis Management in Uganda.

Annals of global health
2026

Twin paradox: Monoamniotic twin pregnancy discordant for limb body wall complex: Presentation of a rare syndrome with a review of embryology.

Ultrasound (Leeds, England)
2026

National trends in gastroschisis factors: maternal age, smoking status, race and ethnicity.

Pediatric surgery international
2026

Embryologic and Developmental Origins of Gastroschisis: A Scoping Review of Historical and Contemporary Theories.

Children (Basel, Switzerland)
2026

A Population-Based Study of U.S. Trends in Selected Congenital Anomalies (2016-2023) and Socio-Demographic Disparities: A CDC WONDER Analysis.

Children (Basel, Switzerland)
2026

Prenatal ultrasound manifestations and classification of 37 fetuses with limb-body wall complex: a retrospective study.

Frontiers in medicine
2026

Spatulated umbilical cord technique embracing Wharton's jelly for gastroschisis repair.

Scientific reports
2026

Is 24 hours enough? evaluating prophylactic antibiotic duration after abdominal wall closure in neonatal gastroschisis.

Journal of pediatric surgery
2026

Maternal risk factors associated with complex gastroschisis: Cannabis exposure and recurrent urinary tract infections may be modifiable targets.

Journal of pediatric surgery
2025

Measuring disease-specific quality of life in pediatric intestinal failure: Development and validation of the PIF-QoL.

Intestinal Failure (New York, N.Y.)
2026

Enteral Feeding Practices Among Infants With Gastroschisis in Canada: A National Cohort Study.

Journal of pediatric surgery
2026

Perinatally Accessible Biomarkers of Complex Gastroschisis: Systematic Review and Individual Patient Data Meta-Analysis.

Prenatal diagnosis
2025

A Historical Review of Gastroschisis: Evolution of Understanding, Diagnosis, and Surgical Management.

Children (Basel, Switzerland)
2026

Gastroschisis: Is the Combination of Diagnosis and Procedure Code Sufficient for Case-Confirmation?

Birth defects research
2026

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 2, Regulatory and Safety Considerations.

Advances in nutrition (Bethesda, Md.)
2026

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 3, Marketing of Infant Formulas, Breastfeeding Support, Hypoallergenic Formulas, and Nutrition for Preterm Infants.

Advances in nutrition (Bethesda, Md.)
2026

Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.

Advances in nutrition (Bethesda, Md.)
2026

Prenatal ultrasound diagnoses fetal amniotic band syndrome causing fetal gastroschisis: A case report.

Medicine
2026

The Relationship between Social Vulnerability Index, Area Deprivation Index, and Child Opportunity Index, and Treatment Course Characteristics in Infants with Surgically Intervenable Congenital Anomalies.

American journal of perinatology
2026

Structural birth defects and exposure to oil and gas wells during pregnancy.

Pediatric research
2026

The association between paternal race and ethnicity and a spectrum of birth defects in a national case-control study.

Annals of epidemiology
2025

When More May Be Better: Reconceptualizing Clinical Handoffs in Modern Medicine.

Cureus
2025

Long-term follow-up of scar quality and satisfaction after surgical closure of congenital abdominal wall defects: a single center perspective.

Pediatric surgery international
2025

Prospective outlook on negative pressure wound therapy (NPWT) for gastroschisis and ruptured omphalocele: A scoping review.

The Medical journal of Malaysia
2025

First experience with 0.31 Tesla low-field MRI in post-mortem fetal examinations.

International journal of legal medicine
2025

Gastroschisis: diagnosis, prognosis and treatment options.

Frontiers in pediatrics
2026

Outcomes of sutureless versus sutured closure for gastroschisis: A systematic review and meta-analysis.

Journal of pediatric surgery
2026

Anesthesia-Related Adverse Events in Infants With Gastroschisis at a South African Tertiary Pediatric Hospital: A Retrospective Cohort Study.

Paediatric anaesthesia
2025

A declining incidence of gastroschisis parallels trends in maternal smoking rates in the United States.

Journal of pediatric surgery
2026

Simulation of cotside silo application, reduction, and sutureless closure, for gastroschisis: Performance of the GABBY-T model.

Journal of pediatric surgery
2025

Maternal Dietary Choices Might Impact Intrauterine Healing Processes and Postnatal Phenotype and Function in Human Fetuses with Spina Bifida Aperta-Early Clinical Observations and Implications from a Retrospective Cohort Study.

Biomedicines
2025

Impact of first-trimester ultrasound on early detection of major fetal anomalies: Nationwide population-based study of over 1 million pregnancies.

PLoS medicine
2025

Antifungal prophylaxis-Where are we today?

Seminars in fetal &amp; neonatal medicine
2026

Enteral autonomy and the role of abdominal surgery in a cohort of infants with gastroschisis.

Journal of pediatric surgery
2025

Extremely Rare Co-occurrence of Left Gastroschisis-Like Abdominal Wall Defect and an Omphalocele in a Very Low Birth Weight Infant: A Case Report.

Surgical case reports
2025

Maternal Health Literacy and Prenatal Learning Experiences Related to Diagnosis and Surgical Management: A Qualitative Study of Women With Pregnancies Associated With Surgically Correctable Congenital Anomalies.

Prenatal diagnosis
2025

Maternal risk factors and closure techniques in gastroschisis: a 16-year retrospective review from a UK tertiary centre.

Pediatric surgery international
2025

Engineering hope: tissue-engineered intestine as a breakthrough for pediatric short bowel syndrome.

Annals of medicine and surgery (2012)
2025

Current status of neonatal surgery in Japan: An analysis of data from the National Clinical Database Pediatric Surgical Registry.

Pediatric surgery international
2025

Late onset small bowel obstruction post Gastroschisis.

Irish medical journal
2026

High-volume hospitals experience fewer postoperative complications after neonatal surgery: Analyses of the National Clinical Database Pediatric Surgical Registry in Japan.

Journal of pediatric surgery
2025

Maternal and offspring outcomes associated with prescribed ADHD medication in pregnancy: a systematic review.

Archives of women's mental health
2025

Systemic inflammation during the neonatal period and BMI at 1 year in infants with gastroschisis: a retrospective cohort study.

European journal of pediatrics
2025

Exclusive human milk for infants with gastroschisis: A systematic review and meta-analysis.

Journal of neonatal-perinatal medicine
2025

Postnatal outcomes of in utero repair of simple gastroschisis in an ovine model.

Journal of pediatric surgery
2025

Neonatal demise from a complex abdominal wall defect in a low-resource setting: A case study on the consequences of a fractured perinatal care cascade.

Radiology case reports
2025

A Challenging Case of Closing Gastroschisis With Gangrenous Bowel: A Case Report.

Cureus
2025

Neurodevelopmental disorders in children with congenital abdominal wall defects: a national population-based study.

Pediatric surgery international
2025

Associations Between Exposure to Extreme Ambient Heat During Periconception and Gastroschisis in Georgia, USA: A Population-Based, Matched Case-Control Study.

Birth defects research
2025

Vanishing Gastroschisis: The Importance of Prenatal Diagnosis in a Seemingly Normal Abdomen.

European journal of pediatric surgery reports
2025

Preformed silo and sutureless closure in gastroschisis.

Anales de pediatria
2025

Trends in incidence of gastroschisis before and after the start of the COVID-19 pandemic.

Journal of perinatology : official journal of the California Perinatal Association
2025

[Predictors of mortality in neonatal spontaneous gastric perforation: a multiple-center study].

Khirurgiia
2025

Association between maternal sexually transmitted diseases and birth defects in the United States: A nationwide population-based study.

Annals of epidemiology
2025

Iatrogenic gastroschisis in an ovine model of left-sided congenital diaphragmatic hernia.

The journal of maternal-fetal &amp; neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
2026

Fetal intestinal prolapse through the maternal vagina in a cryptic pregnancy: A rare case of body stalk anomaly.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2025

Fetoscopic Reduction and Closure for Complex Gastroschisis: A Novel Minimally Invasive Prenatal Approach.

Journal of obstetrics and gynaecology of India
2025

Thyroid Hormone Deficiency Disrupts Embryonic Ventral Body Wall Development and Myogenesis With Partial Recovery Following LevothyroxineTherapy.

Birth defects research
2025

Pedunculated Accessory Liver Lobe Containing the Gallbladder Presenting as Biliary Obstruction: A Case Report.

Cureus
2025

Validation of an instrument prototype for the minimally invasive fetal surgery of gastroschisis in an inanimate model.

Surgical endoscopy
2026

Improved mortality in gastroschisis patients after implementation of a standardized management bundle in central Malawi: A single-center follow-up at four years.

Journal of pediatric surgery
2025

Factors associated with death in newborns with gastroschisis: a retrospective cohort study from a single reference center.

Revista da Associacao Medica Brasileira (1992)
2025

Efficacy and tolerance of neostigmine to improve digestive motility in neonates after gastroschisis surgery: Efficacy and tolerance of neostigmine to improve digestive motility in neonates.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
2026

Critical Organ Dysfunction in Newborns with Gastroschisis.

American journal of perinatology
2025

Prenatal detection rate of congenital anomalies over a period of 30 years: A population-based registry study.

European journal of obstetrics, gynecology, and reproductive biology
2025

Effect of Standard Care Pathway Implementation on Clinical Outcomes and Protocol Utilization in Infants With Gastroschisis.

Journal of pediatric surgery
2025

Factors Affecting Survival of Newborns with Gastroschisis from a Tertiary Care Children's Hospital in India.

Journal of Indian Association of Pediatric Surgeons
2025

Delayed primary surgery and outcomes in children with gastrointestinal anomalies in 264 hospitals and 74 countries.

American journal of epidemiology
2025

Association between transfer for surgery and mortality and disability among neonates in high income countries-A systematic review with meta-analysis.

PloS one
2025

Child and parent mental health outcomes following NICU admission for treatment of congenital anomalies: A systematic review.

Journal of child and adolescent mental health
2025

Distal Ileal Atresia in a Preterm Infant with Minor Omphalocele: A Case Report.

Surgical case reports
2025

Prevalence of Critical Congenital Heart Defects Among Neonates Born With Abdominal Wall Defects.

Prenatal diagnosis
2025

Duodenal Intussusception in an Adult With Situs Inversus Totalis.

Cureus
2025

Gastroschisis - current options for prenatal diagnosis and subsequent management.

Ceska gynekologie
2025

Maternal Age at Birth and Gastroschisis Prevalence in the United States and Puerto Rico, 2000-2020.

Public health reports (Washington, D.C. : 1974)
2025

Systematic Review of the Prevalence of Gastrointestinal Congenital Anomalies: A Global and Regional Review Protocol.

Sage open pediatrics
2025

The Global Burden of Major Gastrointestinal Anomalies: A Global, Systematic Review of Gastrointestinal Anomaly Birth Prevalence.

Sage open pediatrics
2025

Sutureless Abdominal Closure in Monozygotic Twin With Gastroschisis: A Case Report From Muhimbili National Hospital, Tanzania.

Clinical case reports
2025

Anesthesia management for pediatric intestinal transplantation-a single-centre case series of eleven patients.

Canadian journal of anaesthesia = Journal canadien d'anesthesie
2025

Maternal Prenatal Cannabis Use and Major Structural Birth Defects.

Birth defects research
2025

Simple vs. Complex Gastroschisis Outcomes: 30-Year Multicenter Review.

Journal of pediatric surgery
2025

Navigating foreign body ingestion in paediatric patients with a history of congenital abdominal wall defects.

BMJ case reports
2025

Development of external morphological malformations induced by hyperthermia exposure during the blastula stage in an ex-ovo (shell-less) culture of Gallus gallus domesticus embryos.

Poultry science
2025

Imaging of the umbilicus.

Abdominal radiology (New York)
2025

ICAM1 778G>A (rs1799969), ADD1 1378G>T (rs4961), NPPA 553T>C (rs5065), and NOS3 894G>T (rs1799983) Variants in Infants with Gastroschisis from Western Mexico.

Genetic testing and molecular biomarkers
2025

Influenza vaccination during early pregnancy and risk of major birth defects, US Birth Defects Study To Evaluate Pregnancy exposureS, 2014-2019.

Vaccine
2026

Neurodevelopment of children born with gastroschisis: a scoping review.

Pediatric research
2025

The SimpleSilo: An Effective and Affordable Solution for Gastroschisis Management in Low-Resource Settings.

Journal of pediatric surgery
2025

Early versus delayed silo closure in gastroschisis: a retrospective study.

Pediatric surgery international
2025

Pediatric Perioperative Mortality in Southeastern (SE) Nigeria-A Multicenter, Prospective Study.

Nigerian journal of clinical practice
2025

Outbreak of Vancomycin-Resistant Enterococcus in a NICU: Insights into Molecular Detection and Infection Control.

Microorganisms
2025

A 36-week preterm newborn with gastroschisis: a rare case report.

Journal of surgical case reports
2025

Septo-optic dysplasia and gastroschisis: trends in birth prevalence and association with maternal age.

European journal of pediatrics
2025

A survey of long-term NICU developmental follow-up practices in gastroschisis patients.

Journal of perinatology : official journal of the California Perinatal Association
2025

Challenges in Managing Closed Gastroschisis: Addressing a Rare and Complex Variant of Abdominal Wall Defect.

Journal of Indian Association of Pediatric Surgeons
2025

Ratio between Abdominal Defect Size and Abdominal Circumference Measured Preoperatively May Predict Type of Closure in Neonates with Gastroschisis.

Journal of Indian Association of Pediatric Surgeons
2025

Fetal Gastroschisis: Review From Diagnosis to Delivery.

Journal of clinical ultrasound : JCU
2025

Respiratory Support Strategies for Surgical Neonates: A Review.

Children (Basel, Switzerland)
2025

Umbilical morphometry and centile curves in boys aged 1-14 years: Establishing reference values for umbilical reconstruction.

Journal of plastic, reconstructive &amp; aesthetic surgery : JPRAS
2025

Feeding practices for infants with gastroschisis: A survey of neonatal intensive care units in Canada.

Journal of neonatal-perinatal medicine
2025

Decreasing Length of Stay for Simple Gastroschisis: Analysis of the National Surgical Quality Improvement Program (NSQIP).

Journal of pediatric surgery
2025

Birth Prevalence of Gastroschisis in the United States: 2016-2022.

Pediatrics
2025

Decreasing trend of gastroschisis prevalence in the United States from 2014 through 2022: Is attributed to declining birth rates in young, high-risk gravidae.

European journal of obstetrics &amp; gynecology and reproductive biology: X
2025

Congenital Diarrhea and Enteropathies.

NeoReviews
2025

Quality of Life Outcomes in Children Following Surgical Management of Gastroschisis: A Systematic Review and Meta-analysis.

Journal of pediatric surgery
2025

Maternal Diarrhea During the Periconceptional Period and the Risk of Birth Defects, National Birth Defects Prevention Study, 2006-2011.

Birth defects research
2025

Why Has Gastroschisis Increased Over Time and Why Is It More Common in Infants of Young Mothers?

Birth defects research
2025

[Simple gastroschisis complicated by multiple perforations, frozen abdomen, and loss of abdominal domain].

Anales del sistema sanitario de Navarra
2025

Educational Outcomes in School-Aged Children With a History of Simple and Complex Gastroschisis are Poor Compared to Controls.

Journal of pediatric surgery
2025

Global birth prevalence of major congenital anomalies: a systematic review and meta-analysis.

BMC public health
2025

Monitoring and assessment of population, reproductive, and health effects in colonial waterbirds breeding at contaminated Great Lakes sites in Michigan.

Environmental toxicology and chemistry
2025

Prenatal diagnosis of congenital anomalies and birth institution complexity levels in Argentina.

Journal of community genetics
2025

``Prenatally diagnosed gastroschisis: A case report''.

Radiology case reports
2025

Standardized Note Template Expedites Completion of Consults for Surgical Fetal Anomalies.

The Journal of surgical research
2025

Development and Validation of a Minimally Invasive Transuterine Experimental Model of Gastroschisis.

Journal of pediatric surgery
2025

Outcomes of simple gastroschisis surgical treatment in a highly specialized hospital.

Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica
2025

The outcomes of treatment between primary closure and staged closure in gastroschisis in the pre and post era of the bedside wound retractor silo placement technique.

Pediatric surgery international
2025

Burkholderia cenocepacia outbreak linked to taps in a neonatal intensive care unit.

Infection, disease &amp; health
2024

Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review.

Journal of developmental biology
2024

Human Milk-Derived Fortifier to Reduce Hospital-Acquired Malnutrition in Uncomplicated Gastroschisis: A Case Report.

AJP reports
2025

Inter-center variations in inpatient outcomes for infants with gastroschisis from the Children's Hospitals Neonatal Consortium.

Journal of perinatology : official journal of the California Perinatal Association
2025

An exploration of potential risk factors for gastroschisis using decision tree learning.

Annals of epidemiology
2024

Gastrointestinal quality of life in children born with gastroschisis.

Pediatric surgery international
2024

Predictors of outcomes in infants with gastroschisis treated with a preformed silo.

Pediatric surgery international
2024

Anterior abdominal wall defects and their management outcomes in Tikur Anbessa Specialized Hospital, neonatal intensive care unit.

JPGN reports
2024

The burden of adhesive bowel obstruction requiring surgery in children: a single-center retrospective review.

Pediatric surgery international
2025

Prenatal glucocorticoid exposure and congenital abdominal wall defects: Involvement of CXCR4 - SDF-1 signaling.

Mechanisms of ageing and development
2025

Need for Gastroschisis Feeding Protocols.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
2025

Prenatal Ultrasound Markers of Adverse Perinatal Outcomes in Newborns With Simple and Complex Gastroschisis.

Journal of clinical ultrasound : JCU
2025

Fetal Gastroschisis: Maternal Epidemiologic Profile and Influence of Possible Risk Factors on Neonatal Outcomes.

Zeitschrift fur Geburtshilfe und Neonatologie
2024

Assessment of transfer-time and time-to-surgery as risk factors to survival in Gastroschisis (GS) in a LMIC; an eight-year review.

Pediatric surgery international
2024

Short interbirth interval and adverse pregnancy outcomes: a Bayesian network approach.

AJOG global reports
2024

Outcomes of Gastroschisis and Omphalocele Treated at Children's Surgery Verified Centers in Texas.

The Journal of surgical research
2024

Temporal trends in the prevalence of major birth defects in China: a nationwide population-based study from 2007 to 2021.

World journal of pediatrics : WJP
2025

Optimal Strategies for Screening Common Birth Defects in Children of Low- and Middle-Income Countries: A Systematic Review.

Neonatology
2024

Pentalogy of Cantrell Marked With Ectopia Cordis, Gastroschisis, and Cystic Hygroma in the First Trimester: A Rare Case.

Cureus
2024

Burden and mortality of congenital gastrointestinal anomalies: insights from a nationwide cohort study.

Pediatric surgery international
2024

Gastroschisis Prevalence and Co-occurring Malformations Among Danish Live Births During 1994-2021: A Nationwide Register-Based Study.

Journal of pediatric surgery
2024

Management of gastroschisis in an extremely low birth weight infant: report of a case.

Surgical case reports
2024

Association between consensus-based nutrition pathway and growth faltering in infants with gastroschisis: A retrospective cohort study.

JPEN. Journal of parenteral and enteral nutrition
2025

Serial Transverse Enteroplasty (STEP) for Short Bowel Syndrome (SBS) in Children: A Multicenter Study on Long-term Outcomes.

Journal of pediatric surgery
2024

Short bowel syndrome related intestinal failure outcomes in Latin America: Insights from the RESTORE Registry.

JPEN. Journal of parenteral and enteral nutrition
2024

Cutting into the NICU: Improvements in Outcomes for Neonates with Surgical Conditions.

NeoReviews
2024

Non-nutritional use of human milk as a therapeutic agent in neonates: Brain, gut, and immunologic targets.

Early human development
2025

Decisions in Diversion: Enterostomy vs. Primary Anastomosis for Colonic Atresia.

Journal of pediatric surgery
2024

A case of isolated malrotation without midgut volvulus diagnosed prenatally and treated by laparoscopic surgery.

Surgical case reports
2024

Comparison of total prevalence, perinatal prevalence, and livebirth prevalence of birth defects in Hunan Province, China, 2016-2020.

Frontiers in public health
2025

Implementation of standardized feeding pathways for infants with gastroschisis to improve patient outcomes: A quality improvement project in a level IV surgical NICU.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
2025

A New Era in Medical Information: ChatGPT Outperforms Medical Information Provided by Online Information Sheets About Congenital Malformations.

Journal of pediatric surgery
2024

Case Report of a Neonate with Complex Gastroschisis: A Multidisciplinary Approach.

Pediatric reports
2024

Four-Vessel Umbilical Cord: Supernumerary Right Umbilical Vein With No Associated Congenital Anomalies.

Cureus
2024

A Rare case of Neonatal gastroschisis with extraperitoneal intestinal perforation: Timing of abdominal closure.

Asian journal of surgery
2024

Association Between Self-Reported Infections and Seropositivity Among Pregnant Women With Gastroschisis: A Case Control Study, With Emphasis on Chlamydia trachomatis.

Birth defects research
2024

Descriptive epidemiology of gastroschisis in China from 2007 to 2020: a nationwide surveillance-based study.

BMC pediatrics
2024

Colonic atresia and Hirschsprung's disease in a neonate: A case report.

International journal of surgery case reports
2024

A Comparison of Active and Passive Surveillance Strategies for Selected Birth Defects in New York.

Birth defects research
2024

Improving care and survival of newborns with surgical conditions in Tanzania (TINY Tanzania): a focus on gastroschisis.

Pediatric surgery international
2024

Long-term gastrointestinal morbidity in patients born with gastroschisis: A national register-based cohort study.

Journal of pediatric gastroenterology and nutrition
2024

Improving outcomes for uncomplicated gastroschisis: clinical practice guidelines from the American Pediatric Surgical Association Outcomes and Evidence-based Practice Committee.

Pediatric surgery international
2024

Perinatal outcomes of antenatally diagnosed omphalocele and gastroschisis: a survey from a university hospital.

Journal of the Turkish German Gynecological Association
2024

Evaluation of gastroschisis feeding protocol: A retrospective cohort study.

Journal of paediatrics and child health
2024

Concordant fatal congenital anomaly in twin pregnancy: a case report and review of the literature.

Journal of medical case reports
2024

Development of a skeletal muscle sheet with direct reprogramming-induced myoblasts on a nanogel-cross-linked porous freeze-dried gel scaffold in a mouse gastroschisis model.

Pediatric surgery international
2024

Experimental Induction of Complex Gastroschisis in the Fetal Lamb: Systematic Review.

Prenatal diagnosis
2024

Limb body wall complex in a 28-week fetus and impact of cultural beliefs on maternal outcomes: A case report.

SAGE open medical case reports
2024

When all that should close remains open: a tale of gastroschisis, exstrophy of bladder, spina bifida and limb defects.

BMJ case reports
2024

Management and Outcomes of Intestinal Atresia - A Single Institution Experience From 1947 to 2019.

Journal of pediatric surgery
2024

Maternal implications of fetal anomalies: a population-based cross-sectional study.

American journal of obstetrics &amp; gynecology MFM
2024

[Nursing Experience Applying Transition Theory to Assist the Family of an Infant With Complex Congenital Gastroschisis].

Hu li za zhi The journal of nursing
2024

Moderate altitude as a risk factor for isolated congenital malformations. Results from a case-control multicenter-multiregional study.

Birth defects research
2024

Clinical characteristics and outcome of omphalocele and gastroschisis: a 20-year multicenter regional experience.

Pediatric surgery international
2024

A protocol for neoWONDER: Neonatal whole population data linkage to improve long-term health and wellbeing of preterm and sick babies.

PloS one
2024

Newborn screening analytes and structural birth defects among 27,000 newborns.

PloS one
2024

Use of a new vertical traction device for early traction-assisted staged closure of congenital abdominal wall defects: a prospective series of 16 patients.

Pediatric surgery international
2024

[Analysis of Prenatal Ultrasound Manifestations in 15 Cases of Cantrell Syndrome].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
2024

Genitourinary infection and gastroschisis: A systematic review and meta-analysis.

Birth defects research
2024

DETERMINANTS OF OUTCOME OF NEONATAL SURGICAL EMERGENCIES IN GOMBE: A 3-YEAR RETROSPECTIVE REVIEW.

Annals of Ibadan postgraduate medicine
2024

Congenital anomalies in Santa Catarina, Southern Brazil: macroregional and temporal birth prevalence for the period 2011-2020.

Journal of community genetics
2024

Acellular Bovine Pericardial Patch for Difficult Abdominal Closure in the Pediatric Population: Our Experience with Review of Literature.

Journal of Indian Association of Pediatric Surgeons
2024

Prenatal ultrasound markers for prediction of complex gastroschisis-single-center retrospective cohort study.

Journal of perinatology : official journal of the California Perinatal Association
2024

Frequency of gastroschisis and omphalocele and possible influence of maternal folic acid supplementation. A narrative review.

Congenital anomalies
2024

Gastroschisis associated changes in the placental transcriptome.

Placenta
2024

Prevalence of congenital anomalies and prenatal diagnosis by birth institution (public vs. non-public): indicators of inequality in access to elective termination of pregnancy for fetal anomalies.

Journal of community genetics
2025

Long-Term Neurodevelopmental Outcomes in Children with Gastroschisis: A Review of the Literature.

American journal of perinatology
2024

A Rare Case Report of Limb Body Wall Complex.

Cureus
2024

Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations (A Systematic Review From the American Pediatric Surgical Association Outcomes & Evidence Based Practice Committee).

Journal of pediatric surgery
2024

Expansion of the prenatal phenotype of Baraitser-Winter syndrome: Presentation of two cases of multiple congenital anomaly syndrome.

American journal of medical genetics. Part A
2024

Gastroschisis and septo-optic-pituitary dysplasia: Is there an association?

Journal of paediatrics and child health
2024

Major surgical conditions of childhood and their lifelong implications: comprehensive review.

BJS open
2024

A Comparative Analysis of Quality of Life in Children Managed for Omphalocele and Gastroschisis.

African journal of paediatric surgery : AJPS
2024

Very young and advanced maternal age strongly elevates the occurrence of nonchromosomal congenital anomalies: a systematic review and meta-analysis of population-based studies.

American journal of obstetrics and gynecology
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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. A survey of Ugandan skilled birth attendants regarding beliefs and management of gastroschisis.
    BMJ global health· 2026· PMID 41802825mais citado
  2. Epidemiological profile of pregnant women and perinatal outcomes of newborns with gastroschisis from a single reference center in Northeastern Brazil.
    Ceska gynekologie· 2026· PMID 41841537mais citado
  3. Clinical Presentation and Diagnostic Challenges of Congenital Thoracoabdominal Wall Defects in Dogs: Insights from a Case Series and Literature Synthesis.
    Animals : an open access journal from MDPI· 2026· PMID 41828911mais citado
  4. Patient-Reported Long-Term Gastrointestinal Outcomes in Children with Omphalocele and Gastroschisis: A PedsQL GI Module Study.
    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie· 2026· PMID 41819136mais citado
  5. A Pilot Study to Advance Task-Sharing of Gastroschisis Management in Uganda.
    Annals of global health· 2026· PMID 41767796mais citado
  6. Preterm delivery promotes a high primary reduction in simple gastroschisis and the exit-like technique may improve the outcomes.
    Pediatr Surg Int· 2026· PMID 41954742recente
  7. Trends in Gastroschisis in the State of Paraná, Brazil: A Study of Incidence, Mortality, and Associated Factors (2013-2024).
    Int J Environ Res Public Health· 2026· PMID 41899764recente
  8. Closing/Closed Gastroschisis (CGS): Antenatal Predictors and Surgical Strategies in Cases of Unique Anatomy from a Case Series.
    Children (Basel)· 2026· PMID 41897120recente
  9. Establishing gastroschisis care: impact of pediatric surgical services and a dedicated neonatal surgical unit on survival of gastroschisis in Rwanda.
    J Pediatr Surg· 2026· PMID 41895460recente
  10. [Prevalence and mortality factors in initial hospitalization for gastroschisis].
    Andes Pediatr· 2025· PMID 41842777recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:2368(Orphanet)
  2. OMIM OMIM:230750(OMIM)
  3. MONDO:0009264(MONDO)
  4. GARD:8661(GARD (NIH))
  5. Busca completa no PubMed(PubMed)
  6. Artigo Wikipedia(Wikipedia)
  7. Q1495674(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Gastrosquise
Compêndio · Raras BR

Gastrosquise

ORPHA:2368 · MONDO:0009264
Prevalência
1-5 / 10 000
Herança
Not applicable
CID-10
Q79.3 · Gastrosquise
CID-11
Ensaios
7 ativos
Início
Antenatal
Prevalência
0.0 (Europe)
MedGen
UMLS
C0238577
EuropePMC
Wikidata
Wikipedia
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