Raras
Buscar doenças, sintomas, genes...
Oclusão da veia central da retina
ORPHA:411527CID-10 · H34.8CID-11 · 9B74.1DOENÇA RARA

Entupimento da veia central da retina.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

Entupimento da veia central da retina.

Pesquisas ativas
3 ensaios
99 total registrados no ClinicalTrials.gov
Publicações científicas
2.745 artigos
Último publicado: 2026 Apr 15

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-5 / 10 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
28.0
Europe
Início
Adult
+ elderly
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: H34.8
Você se identifica com essa condição?
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

👁️
Olhos
12 sintomas
❤️
Coração
2 sintomas

+ 2 sintomas em outras categorias

Características mais comuns

90%prev.
Edema macular cistoide
Muito frequente (99-80%)
90%prev.
Mancha algodonosa macular
Muito frequente (99-80%)
90%prev.
Hemorragia intrarretiniana
Muito frequente (99-80%)
55%prev.
Perda visual
Frequente (79-30%)
55%prev.
Papiledema
Frequente (79-30%)
55%prev.
Edema macular
Frequente (79-30%)
16sintomas
Muito frequente (3)
Frequente (4)
Ocasional (9)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 16 características clínicas mais associadas, ordenadas por frequência.

Edema macular cistoideCystoid macular edema
Muito frequente (99-80%)90%
Mancha algodonosa macularMacular cotton wool spot
Muito frequente (99-80%)90%
Hemorragia intrarretinianaIntraretinal hemorrhage
Muito frequente (99-80%)90%
Perda visualVisual loss
Frequente (79-30%)55%
PapiledemaPapilledema
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico2.745PubMed
Últimos 10 anos200publicações
Pico2025102 papers
Linha do tempo
2026Hoje · 2026🧪 1988Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado6
3Fase 34
2Fase 22
1Fase 11
·Pré-clínico7
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Oclusão da veia central da retina

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

1 pesquisa recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

99 ensaios clínicos encontrados, 3 ativos.

Distribuição por fase
NCT05476926 · A Real-World Study to Gain Clinical Insights Into Roche Opht…Ativo
NCT07240649 · Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emergin…Em breve
PHASE4
NCT01295112 · Effect of Ozurdex® 0.7 mg on Improvement of Efficacy of Beva…Concluído
PHASE2, PHASE3
NCT04667910 · 601 Versus Ranibizumab in Patients With Central Retinal Vein…Concluído
PHASE2
NCT04793100 · Spontaneous Retinal Artery Pulses (SPARs) as a Prognostic De…Concluído
NA
NCT05832996 · Cool vs Room-temperature Artificial TearsConcluído
PHASE4
NCT03981549 · Treatment of Central Retinal Vein Occlusion Using Stem Cells…Concluído
PHASE1, PHASE2
NCT06708624 · Ocular Safety and Usability Study for FYB201 PFSConcluído
PHASE4
NCT06708637 · Ocular Safety and Usability Study for FYB203 PFSConcluído
PHASE4
NCT04740931 · A Study to Evaluate the Efficacy and Safety of Faricimab in …Concluído
PHASE3
NCT06495203 · A Study to Understand the Usage of an Artificial Intelligenc…Concluído
NCT00566761 · Treatment of Bevacizumab and Triamcinolone in Treatment or M…Encerrado
PHASE4
NCT06416241 · Intravitreal Aflibercept for Macular Edema Due to Central Re…Concluído
PHASE4
NCT02880644 · Ultra-wide Fluorescein Angiography in Patients With Central …Concluído
NCT03417401 · Surgical Stabilizer Assisted RVC With rtPA for CRVOCancelado
PHASE1
NCT03810313 · Assessing the Efficacy and Safety of Brolucizumab Versus Afl…Encerrado
PHASE3
NCT00556114 · A Pilot Study of Functional Optical Coherence Tomography for…Concluído
NCT04812977 · Comparison of Intravitreal Anti-VEGF Versus Combination Ther…Concluído
NA
NCT02390245 · Philadelphia Telemedicine Glaucoma Detection and Follow-Up S…Concluído
NA
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
1.234 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 1.234

#1

Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility.

Ophthalmology science2026 Jan

To assess the safety and feasibility of intravitreal injection of autologous CD34+ bone marrow stem cells (BMSCs) in eyes with vision loss from central retinal vein occlusion (CRVO). Phase I/II single-center, prospective, randomized, sham-controlled, double-masked study. Participants with CRVO of 6 to 42 months duration, best-corrected visual acuity (VA) of 20/40 to 20/400, and no concurrent retinopathy or optic neuropathy contributing to vision loss in the study eye. The exclusion criteria include any concurrent systemic condition that would alter bone marrow components. Participants were randomized to immediate cell injection followed by sham injection at month 6 or immediate sham injection followed by cell injection at month 6. Cell injection consisted of a bone marrow aspiration and intravitreal injection of autologous CD34+ BMSCs. CD34+ BMSCs were isolated from the mononuclear cell fraction of bone marrow using Miltenyi CliniMACS system under current good manufacturing practices. Isolated cells were released for intravitreal injection if they passed the release criteria for quantity, sterility, and viability accepted by the US Food and Drug Administration. Sham injection consisted of a sham bone marrow aspiration and intravitreal injection without entering bone or eye. Eye examination, microperimetry, fundus photography, fluorescein angiography, electroretinography, OCT, and OCT angiography were performed at baseline and during study follow-up of 12 months. Adverse events (AEs) associated with study treatment, number of CD34+ BMSCs injected intravitreally. Sixteen participants (16 eyes) were randomized to 1 of 2 study groups. All received intravitreal injection of autologous CD34+ BMSCs (mean 4.3 million cells) and completed the study follow-up. Rubeosis with vitreous hemorrhage occurred in 1 study eye, <1 month after sham injection and 7 months after cell injection, attributed to normal progression of CRVO. There were no other serious ocular AEs. The most common AE related to the study cell injection was new floaters (15/16, 93%). Other ocular AEs were similarly noted after sham injection. No eye had persistent VA loss of ≥15 letters after cell injection. Intravitreal injection of autologous CD34+ BMSCs appears well-tolerated and feasible in eyes with vision loss from CRVO. Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

#2

Intravitreal Dexamethasone Implant in Retinal Vein Occlusion: A Pilot Study Exploring Baseline Ocular and Circulating Biomarkers.

International journal of molecular sciences2026 Jan 16

This pilot study assessed the effectiveness of the intravitreal dexamethasone implant (Ozurdex) in retinal vein occlusion (RVO) patients and explored potential pre-treatment biomarkers to improve management and prognosis. Eighteen patients with branch RVO (BRVO) and twenty-four with central RVO (CRVO) receiving two intravitreal injections of Ozurdex (at baseline and between 4 and 6 months) were included. Best-corrected visual acuity (BCVA) and central retinal thickness (CRT) were recorded at baseline and after 3, 6, and 12 months. Retinal morphology was assessed using optical coherence tomography (OCT), and serum biomarkers were analyzed by ELISAs. No significant BCVA improvement was observed in RVO patients, while CRT significantly decreased from 3 to 12 months. Patients without defects of the retinal inner layers, ellipsoid zone, and external limiting membrane showed significantly higher BCVA at 6 and 12 months. Both BRVO and CRVO groups demonstrated significant BCVA improvement and CRT reduction at 6 and 12 months, with better outcomes in BRVO patients. These patients exhibited lower baseline serum levels of xanthine oxidase (XO) and thrombospondin-1 (TSP-1), which inversely correlated with BCVA at 12 months. Ozurdex was effective in real-life RVO treatment, particularly in BRVO. Serum XO and TSP-1 may serve as prognostic biomarkers for RVO.

#3

Corrigendum to "Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility. Ophthalmol Sci. 2026;6:100905".

Ophthalmology science2026 Feb

[This corrects the article DOI: 10.1016/j.xops.2025.100905.].

#4

Simultaneous Branch Retinal Artery and Central Retinal Vein Occlusions following Blood Transfusion in a Young Man: A Case Report.

Case reports in ophthalmology2026

Simultaneous branch retinal artery occlusion (BRAO) and central retinal vein occlusion (CRVO) is an exceptionally rare cause of acute vision loss, particularly in young individuals without systemic vascular risk factors. Blood transfusion has been implicated in rare thromboembolic and hyperviscosity-related complications but is infrequently associated with retinal vascular occlusions. A 20-year-old man presented with sudden painless unilateral vision loss shortly after receiving a packed red blood cell transfusion for severe anemia. Ophthalmic examination revealed optic disc edema, venous engorgement, scattered retinal hemorrhages, and superior hemi-macular whitening in the affected eye. Structural optical coherence tomography demonstrated inner retinal hyperreflectivity and subsequent thinning, consistent with ischemic retinal injury. Fluorescein angiography was contraindicated due to an acute hypersensitivity reaction. Extensive systemic, hematologic, inflammatory, and thrombophilia workup was unremarkable. Despite conservative and supportive management, including hyperbaric oxygen therapy and anticoagulation, visual recovery remained limited at follow-up. This case highlights a rare presentation of concurrent BRAO and CRVO occurring shortly after blood transfusion in a young patient without identifiable systemic risk factors. Although causality cannot be definitively established, the close temporal relationship and exclusion of alternative etiologies suggest transfusion-related rheologic changes as a plausible contributing factor. Clinicians should remain vigilant for acute retinal vascular events following transfusion, even in young patients, and prompt ophthalmic evaluation is essential. This report describes an unusual eye problem that developed in a young man shortly after receiving a blood transfusion. The retina is the thin, light-sensitive tissue at the back of the eye that allows us to see. It receives blood through tiny arteries and drains blood through tiny veins. In this case, both an artery and a vein became blocked at the same time in the same eye, which is extremely rare. An artery blockage reduces the supply of oxygen to the retina, while a vein blockage causes pressure to build up and blood to collect inside the retina. When both occur together, vision can suddenly become blurred or dark because the retina is affected in two different ways at once. The patient experienced serious vision loss shortly after his transfusion. When examined, he was found to have signs of both types of blockage. Imaging of the retina confirmed these findings. Although blood transfusion is usually safe, temporary changes in blood thickness can happen, especially in young people. These changes may increase the chance of blood flow becoming sluggish in the eye, which can contribute to blockage in rare situations. This summary explains what happened in this unusual case, why it is medically significant, and how it may help doctors recognize similar problems early. Understanding this event may support quicker diagnosis and appropriate management when sudden vision loss occurs after a transfusion.

#5

[A case of antiphospholipid syndrome complicated with hyperhomocysteinemia presenting initially with central retinal vein occlusion in a young male].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology2026 Mar 11

A 28-year-old male presented to the ophthalmology department with decreased visual acuity in the left eye for 4 months. Four months prior, he was diagnosed with central retinal vein occlusion (CRVO) in the left eye at another hospital and received three intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents. Laboratory examinations revealed elevated levels of homocysteine, lupus anticoagulant (LA) 1 screening test result, LA1/LA2 ratio, and anti-β2 glycoprotein 1 antibody. The patient was treated with oral folic acid tablets, systemic anticoagulants, and additional intravitreal anti-VEGF therapy. He achieved a favorable prognosis after treatment. 患者男性,28岁。因左眼视力下降4个月就诊眼科。患者左眼4个月前在外院诊断为左眼视网膜中央静脉阻塞,给予3次玻璃体腔抗血管内皮生长因子药物注射治疗。实验室检查示同型半胱氨酸水平、狼疮抗凝物(LA)1筛查试验,LA1/LA2,抗β2糖蛋白1抗体数值均升高。给予患者全身口服叶酸片及抗凝药物治疗,局部玻璃体腔抗VEGF治疗后患者预后良好。.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC1.535 artigos no totalmostrando 200

2025

Poor glycemic control impairs recovery from central retinal vein occlusion.

Molecular vision
2026

Simultaneous Branch Retinal Artery and Central Retinal Vein Occlusions following Blood Transfusion in a Young Man: A Case Report.

Case reports in ophthalmology
2026

[A case of antiphospholipid syndrome complicated with hyperhomocysteinemia presenting initially with central retinal vein occlusion in a young male].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2026

Evaluation of the Effects of Intravitreal Application of an Ozurdex Implant in Patients with Macular Edema due to Retinal Vein Occlusion.

Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti
2026

Risks of Retinal Vascular Occlusions with the Systemic Use of Tyrosine Kinase Inhibitors.

Ophthalmology. Retina
2026

Long-term Outcomes of 3+PRN Versus 5+PRN Anti-VEGF Regimens for Ischemic and Non-ischemic Central Retinal Vein Occlusion-Associated Macular Edema.

Photodiagnosis and photodynamic therapy
2026

Combined Central Retinal Vein and Artery Occlusion Following Head Trauma: A Case Report.

Retinal cases &amp; brief reports
2026

Association Between Retinal Vein Occlusion and Epiretinal Membrane Development.

American journal of ophthalmology
2026

Aqueous humour cytokine profiles in retinal vein occlusion: a comparative study of acute, chronic recurrent, and control eyes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2026

Machine Learning to Predict Outcomes and Dosing Frequency With Aflibercept for Macular Edema Following Central Retinal Vein Occlusion.

Ophthalmic surgery, lasers &amp; imaging retina
2026

Safety and efficacy of anti-vascular endothelial growth factor (VEGF) plus corticosteroids versus anti-VEGF alone for macular edema from retinal vein occlusion: A systematic review and meta-analysis.

Survey of ophthalmology
2026

Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility.

Ophthalmology science
2026

Dengue fever case report: a red flag for retinal vein occlusion.

AME case reports
2026

Long-Term Risk of Mortality and Systemic Morbidity in Neovascular Glaucoma: A Multicenter Retrospective Cohort Study.

Ophthalmology. Glaucoma
2026

Dim Flicker: An Endogenous Visual Percept and Its Disease Associations.

Journal of clinical medicine
2026

Intravitreal Dexamethasone Implant in Retinal Vein Occlusion: A Pilot Study Exploring Baseline Ocular and Circulating Biomarkers.

International journal of molecular sciences
2026

Saved by My Specs: Incidental central retinal vein occlusion uncovering infective endocarditis - A case report.

IDCases
2026

Corrigendum to "Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility. Ophthalmol Sci. 2026;6:100905".

Ophthalmology science
2025

Sequential Bilateral Central Retinal Vein Occlusion With Differential Long-Term Outcomes Following Cardiac Surgery.

Cureus
2026

Central Retinal Vein Occlusion in Pregnancy: A Rare Case Report.

Annals of African medicine
2026

Central retinal vein occlusion in hemophilia B: between bleeding and thrombosis.

Polish archives of internal medicine
2025

Wipe-Out Syndrome After PreserFlo MicroShunt Implantation in a Patient With Pseudoexfoliation Glaucoma.

Cureus
2025

Unilateral Central Retinal Vein Occlusion in a Young Adult With Latent Syphilis.

Cureus
2026

Ranibizumab on optic disc perfusion in central retinal vein occlusion.

International journal of ophthalmology
2025

Neovascularization of the Iris/Angle in Primary Angle Closure Glaucoma: A Distinct Entity!

Journal of current glaucoma practice
2025

Ocular decompression retinopathy after anterior chamber paracentesis - Case series and systematic review.

Taiwan journal of ophthalmology
2026

The serum level of leucine-rich alpha-2 glycoprotein to differentiate between ischemic and non-ischemic retinal vein occlusion.

Photodiagnosis and photodynamic therapy
2026

Predictive Value of Optical Coherence Tomography Biomarkers on Visual Outcomes in Patients with Retinal Vein Occlusion.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
2026

Surgical Outcomes of Ahmed Glaucoma Valve in Neovascular Glaucoma Secondary to Diabetic Retinopathy Versus Central Retinal Vein Occlusion.

Journal of glaucoma
2026

Mortality in neovascular glaucoma.

Indian journal of ophthalmology
2025

Enhancing Undergraduate Ophthalmology Teaching Through Virtual Reality: Integrating the Eyesi Direct Ophthalmoscopy Simulator.

Cureus
2025

Impact of anti-VEGF therapy on choroidal thickness in patients with retinal vein occlusion: a systematic review and meta-analysis.

Frontiers in medicine
2025

Central retinal vein occlusion following intravitreal injections: a case series highlighting multifactorial risk.

International journal of retina and vitreous
2025

Combined Treatment of Hyperbaric Oxygen and Anti-vascular Endothelial Growth Factor Therapy in Cilioretinal Artery Occlusion Associated With Central Retinal Vein Occlusion.

Cureus
2025

Interaction Between Glaucoma and Central Retinal Vein Occlusion in a Cohort Study.

Journal of clinical medicine
2025

Triglyceride-glucose index as a potential biomarker for predicting retinal vein occlusion.

Scientific reports
2026

Prognostic Value of Multimodal Imaging in Retinal Vein Occlusion: A Prospective Study from a North African Tertiary Center.

Ophthalmic surgery, lasers &amp; imaging retina
2025

Aqueous Humor Proteome in RVO-Associated Macular Edema: Analysis during Three Consecutive Conbercept Treatments.

ACS omega
2025

Ocular Blood Velocity Measurement With Optical Coherence Tomography Using Speckle Analysis.

Translational vision science &amp; technology
2025

[Characterization of collateral circulation after anti-VEGF treatment for retinal vein occlusion].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2025

Real-life short-term experience of switching from other anti-VEGF therapy to faricimab in patients with refractory macular edema secondary to retinal vein occlusion in China.

International ophthalmology
2025

Evaluation of Cardiovascular Risk Scores and their Association With Vascular Structural Changes in Patients With Retinal Vein Occlusion.

Angiology
2025

A multicenter, single-arm study using a modified faricimab treat-and-extend regimen in patients with macular edema due to central retinal vein occlusion: RVOSTAR study design protocol.

PloS one
2025

The Features of Vessel Densities and Hemorheological Parameters in Patients With Central Retinal Vein Occlusion: A Prospective Randomized Case-Control Study.

Journal of ophthalmology
2025

Case Report: Papillophlebitis associated with MOG-IgG-associated optic neuritis.

Frontiers in medicine
2025

Evaluating the quantity and spatial density of macrophage-like cells in patients with retinal vascular disease and healthy subjects via non-invasive retinal imaging.

International journal of retina and vitreous
2025

Young-Onset Central Retinal Vein Occlusion with Antiphospholipid Syndrome and Hypophysitis.

Case reports in ophthalmology
2025

Tuberculosis-Related Neuroretinitis and Central Retinal Vein Occlusion in a Child, and a Literature Review.

Case reports in ophthalmology
2025

Relationship Between COVID-19 and Retinal Vein Occlusions.

Journal of ophthalmology
2026

Central retinal vein occlusion in a healthy female patient with etonogestrel contraceptive implant.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
2025

Manual measurement of SD-OCT images of hyperreflective retinal layers in acute retinal vessel occlusion is reliable, repeatable and reproducible.

Scientific reports
2025

Quantification of intermittent retinal capillary perfusion in retinal vein occlusion and proliferative diabetic retinopathy.

International journal of retina and vitreous
2025

Neovascular glaucoma: comprehensive evaluation of etiology, treatment modalities, and visual prognosis.

BMC ophthalmology
2025

Central Retinal Artery Occlusion After Intravitreal Injection of Faricimab: A Case Report.

Cureus
2025

Updates in the treatment of neovascular glaucoma: From conventional approaches to novel therapies.

Indian journal of ophthalmology
2025

Neovascular glaucoma associated with central retinal vein occlusion in a young patient with hyperlipidemia.

The Journal of international medical research
2025

Profound Vision Loss With Minimal Retinal Findings: A Case of Microvascular Ischemia Unraveled by Multimodal Imaging.

Cureus
2026

[Central retinal vein occlusion in marathon runner's retinopathy].

Die Ophthalmologie
2025

Smoking and Chronic Obstructive Pulmonary Disease: Key Contributors to Central Retinal Vein Occlusion in an Elderly Patient.

The American journal of case reports
2025

Evaluation of optical coherence tomography angiography role in differentiating ischemic and non-ischemic central retinal vein occlusion.

International ophthalmology
2025

The One Percent Stroke: A Case Report.

Cureus
2025

Jueling Mingmu decoction combined with ranibizumab for retinal vein occlusion induced macular edema: A randomized controlled clinical trial.

International ophthalmology
2025

Sterile Intraocular Inflammation in Patients Receiving Both Faricimab and High-Dose Aflibercept in Consecutive Order.

Journal of vitreoretinal diseases
2025

Short-Term Follow-Up Study on the Efficacy and Safety of Intravitreal Bevacizumab for Macular Edema Secondary to Retinal Venous Occlusions.

Cureus
2025

Development of Superficial Thrombophlebitis and Subsequent Central Retinal Vein Occlusion Occurring in a Patient Receiving IVIg for Ocular Pemphigoid.

Ocular immunology and inflammation
2025

Case Report: Obstructive sleep apnea syndrome-associated blood pressure fluctuations combined with simultaneous central retinal vein and artery occlusion.

Frontiers in medicine
2025

Ocular and Systemic Risk Factors and Clinical Implications in Glaucoma Patients With Retinal Vein Occlusion.

Journal of glaucoma
2025

Assessment of Systemic Inflammatory Biomarkers in Neovascular Glaucoma.

Ocular immunology and inflammation
2025

Clinical profile of patients with retinal vein occlusion and its correlation with serum homocysteine levels.

BMC ophthalmology
2025

Influence of Retinal Venous Pressure on Visual and Structural Outcomes in Eyes with Central Retinal Vein Occlusion Undergoing Anti-VEGF Treatment.

Clinical ophthalmology (Auckland, N.Z.)
2024

Concurrent Onset of Central Retinal Vein Occlusion and Inflammation of a Large Maxillary Odontogenic Cyst: Case Report and Analysis.

Reports (MDPI)
2025

Effect of Hypoxia on Adult Müller Glia Cultures.

Biomedicines
2025

Unusual case of bilateral combined central retinal artery and central retinal vein occlusion as a complication of papilledema.

Journal francais d'ophtalmologie
2025

Central Retinal Vein Occlusion Associated With Progestin-Only Contraceptive Implant Use.

Case reports in ophthalmological medicine
2025

Persistent central retinal vein occlusion (CRVO) in protein S and C4b complement deficiency.

BMJ case reports
2025

Ultra-Widefield Retinal Optical Coherence Tomography (OCT) and Angio-OCT Using an Add-On Lens.

Diagnostics (Basel, Switzerland)
2025

Central Retinal Vein Occlusion (CRVO) complicating post-cataract surgery: a case report and multifactorial analysis.

BMC ophthalmology
2025

Prognostic biomarkers in treatment-naïve central retinal vein occlusion with macular edema.

European journal of medical research
2025

Comparison of Choroidal Thickness in Affected and Fellow Eyes of Treatment-Naive Retinal Vein Occlusion Patients.

Cureus
2025

Effect of combined therapy based on transscleral peripheral retinal cryotherapy in the treatment of open-angle neovascular glaucoma: a retrospective study.

BMC ophthalmology
2025

Significant Correlation Between Retinal Blood Flow and Oxygen Saturation During Intravitreal Aflibercept Treatment for Central Retinal Vein Occlusion.

Translational vision science &amp; technology
2025

Artificial Intelligence-Based Detection of Central Retinal Artery Occlusion Within 4.5 Hours on Standard Fundus Photographs.

Journal of the American Heart Association
2025

A Comparison of All-Cause Mortality in Patients Who Required Glaucoma Surgery for Neovascular Glaucoma or Primary Open-Angle Glaucoma: A Retrospective Cohort Study.

Vision (Basel, Switzerland)
2025

Therapeutic potential of artesunate in retinal diseases: from mechanism to clinical applications.

International journal of ophthalmology
2025

A PROSPECTIVE OBSERVATIONAL STUDY OF INTRAVITREAL AFLIBERCEPT IN RETINAL VEIN OCCLUSION WITH INITIALLY GOOD VISUAL ACUITY.

Retina (Philadelphia, Pa.)
2025

Long-term visual outcome and retinal function with and without intravitreal treatments in eyes with central retinal vein occlusion.

European journal of ophthalmology
2025

Venous stasis retinopathy in increased intracranial pressure.

BMJ case reports
2025

Fighting steroids with steroids: a case of bilateral central retinal vein occlusion in an anabolic steroid user.

The New Zealand medical journal
2025

Integration of proteomics and artificial intelligence-driven OCT biomarker analysis in central retinal vein occlusion.

Experimental eye research
2025

Lamina cribrosa perfusion density is reduced in eyes with central retinal vein occlusion.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2026

Arteriovenous Malformation with Central Retinal Vein Occlusion and Intraretinal Hyporeflective Spaces.

Ophthalmology. Retina
2025

"Cilioretinal artery occlusion: Current scenario".

European journal of ophthalmology
2026

Multimodal intervention of acute central retinal vein occlusion and Takayasu retinopathy in long-standing Takayasu arteritis.

Clinical &amp; experimental optometry
2025

Risk of Adverse Systemic Events in Retinal Vein Occlusion.

Ophthalmology. Retina
2025

Baseline macular structural and vascular changes as predictive markers of visual improvement in central retinal vein occlusion.

Northern clinics of Istanbul
2025

Effect of Obstructive Sleep Apnea Syndrome on Macular Edema Severity and Response to Intravitreal Ranibizumab in Diabetic Retinopathy and Retinal Vein Occlusion.

Cureus
2025

Construction and validation of risk prediction models for different subtypes of retinal vein occlusion.

Advances in ophthalmology practice and research
2025

Intravitreal Dexamethasone Implant for Patients With Central Retinal Vein Occlusion: Four-Year Outcomes in a Real-World Study.

Cureus
2025

Real-World Intravitreal Aflibercept 2 mg Treatment of Macular Oedema Secondary to Retinal Vein Occlusion in Italy: 24-Month Results from the AURIGA Observational Study.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
2025

Ipsilateral, Multi-Phasic Retinal Vascular Events following Intralesional Triamcinolone Acetonide Injection for Earlobe Keloid: A Case Report.

Case reports in ophthalmology
2025

Intravitreal aflibercept for macular edema due to central retinal vein occlusion: 5-year results of a real-world study (INTRAMED-CRVO).

Retina (Philadelphia, Pa.)
2025

Structural and Vascular Features of Macula Related to the Recurrence of Macular Edema in Central Retinal Vein Occlusion After Anti-VEGF Therapy.

Journal of ophthalmology
2025

A rare case of aggressive pyoderma gangrenosum with Cogan syndrome in a person with skin of colour.

Skin health and disease
2025

Exploring the ocular involvement in multiple myeloma: a comprehensive review of 70-year clinical studies.

International ophthalmology
2025

Is there an association between retinal vein occlusion and cerebrovascular accident? A systematic review and meta-analysis.

BMC ophthalmology
2025

[Deeply understanding the pathological characteristics of diabetic retinopathy and central retinal vein occlusion and the similarities and differences in therapeutic strategies].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
2025

Safety of an Intravitreal Bevacizumab Biosimilar (MVASI).

Clinical &amp; experimental ophthalmology
2025

Optical Coherence Tomography-Guided Early Versus Late Switching to Dexamethasone Implants in Macular Edema Related to Central Retinal Vein Occlusion: Real-World Evidence.

Diagnostics (Basel, Switzerland)
2025

Electrodiagnostic Tests as Potential Efficacy Endpoints in Clinical Trials of Novel Pharmacological Therapies for Acquired Retinal Disorders.

Ophthalmic research
2025

Comparison of the effect of ranibizumab in retinal vein occlusion and macular edema with different optical coherence tomographic patterns.

International journal of ophthalmology
2024

Atypical Delayed-Onset Endophthalmitis Following Intravitreal Dexamethasone Implant Managed Without Implant Removal: A Rare Case Report and Literature Review.

Romanian journal of ophthalmology
2025

A case of Bartonella Neuroretinitis Presenting with Concomitant Frosted Branch Angiitis on long-term follow-up.

Retinal cases &amp; brief reports
2025

CHANGE IN RETINAL PERFUSION WITH AFLIBERCEPT FOR CENTRAL RETINAL VEIN OCCLUSION: The Two-Year Prospective Observational HERMES Study.

Retina (Philadelphia, Pa.)
2026

ENORMOUS BILATERAL OPTIC DISK DRUSEN PRESENTING AS A CENTRAL RETINAL VEIN AND CILIORETINAL ARTERY OCCLUSION.

Retinal cases &amp; brief reports
2025

Dynamic Complement Protein Changes in Aqueous Humor and Plasma of Patients With Retinal Vein Occlusion During Ranibizumab Treatment.

Journal of inflammation research
2025

Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report.

Biomedicines
2025

The Diagnosis and Treatment of Branch Retinal Vein Occlusions: An Update.

Biomedicines
2025

Normalized Reflectivity of Middle Limiting Membrane on SD-OCT: A Measure of Acute Ischemia in CRVO.

Current eye research
2025

Simultaneous central retinal vein and cilioretinal artery occlusion in a young female patient with progestin-only oral contraceptive use: a case report.

Journal of medical case reports
2025

Teleguided photocoagulation treatments across continents with a remotely programmed laser for retinal diseases.

Therapeutic advances in ophthalmology
2025

Presumed Sympathetic Ophthalmia After Diode Laser Cyclophotocoagulation for Neovascular Glaucoma: A Case Series.

Ocular immunology and inflammation
2024

Wide field imaging biomarkers: A different perspective.

Taiwan journal of ophthalmology
2024

Visually significant ocular decompression retinopathy following laser peripheral iridotomy in a patient with primary acute angle-closure glaucoma.

American journal of ophthalmology case reports
2025

Anterior Segment Optical Coherence Tomography Evaluation of a Dexamethasone Intravitreal Implant in the Crystalline Lens: A Case Report.

International medical case reports journal
2025

Untargeted Metabolomic Study of Patients with Macular Edema Secondary to Retinal Vein Occlusion in Aqueous Humor.

Clinical ophthalmology (Auckland, N.Z.)
2025

Atrial Fibrillation and Retinal Stroke.

JAMA network open
2024

Case report: Cilioretinal artery occlusion combined with central retinal vein occlusion as the initial presentation of pulmonary arterial hypertension.

Frontiers in medicine
2025

Machine Learning Quantification of Fluid Volume in Eyes With Retinal Vein Occlusion Treated With Aflibercept: The REVOLT Study.

Journal of vitreoretinal diseases
2024

Long term efficacy and safety profile of dexamethasone intravitreal implant in retinal vein occlusions: a systematic review.

Frontiers in medicine
2024

Evaluating ChatGPT's Diagnostic Accuracy in Detecting Fundus Images.

Cureus
2025

Automated Detection of Central Retinal Artery Occlusion Using OCT Imaging via Explainable Deep Learning.

Ophthalmology science
2024

[Retinal artery and vein occlusions].

Nederlands tijdschrift voor geneeskunde
2024

Clopidogrel therapy in nonischemic central retinal vein occlusion: A case report and therapeutic insight.

Oman journal of ophthalmology
2025

Combined central retinal vein occlusion and cilioretinal artery occlusion in two young patients.

Archivos de la Sociedad Espanola de Oftalmologia
2024

Rapid-onset central retinal vein occlusion following inactivated COVID-19 vaccination.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
2024

Central retinal vein occlusion after infliximab therapy in a young patient with ulcerative colitis.

JPGN reports
2024

Complement C3 is downregulated following ranibizumab intervention in experimental central retinal vein occlusion.

Molecular vision
2024

Short-term fluctuation of intraocular pressure and influencing factors following intravitreal injection in patients with retinal vascular diseases.

International journal of ophthalmology
2024

Suprachoroidal Triamcinolone Acetonide Injection to Treat Macular Edema: A Review.

Journal of vitreoretinal diseases
2024

Is retinal vein occlusion highly associated with an increased risk of myocardial infarction? A systematic review and meta-analysis.

International journal of retina and vitreous
2024

Retinal vascular events and relationship to CANCER development.

Thrombosis research
2024

Surgical Outcomes of Mitomycin-C Augmented Trabeculectomy in Neovascular Glaucoma and Prognostic Factors for Surgical Failure in Thailand.

Clinical ophthalmology (Auckland, N.Z.)
2024

A rare case of systemic lupus erythematosus presenting with concurrent myocarditis, central retinal vein occlusion, and deep vein thrombosis.

Clinical case reports
2024

A Rare Presentation of Myelin Oligodendrocyte Glycoprotein-Associated Optic Neuritis with Venous Stasis Retinopathy and Premacular Hemorrhage: A Case Report.

Case reports in ophthalmology
2024

Effects of intravitreal Bevacizumab (Avastin) monotherapy in central retinal vein occlusion in young subjects.

Romanian journal of ophthalmology
2025

Tortuous conjunctival vessels and central retinal vein occlusion in spontaneous dural arteriovenous fistula.

Eye (London, England)
2024

Efficacy and Safety of an Indian Bevacizumab BIOSimilar (BEVATAS) for Retinal Vein Occlusion (BIOS-RVO Study).

Clinical ophthalmology (Auckland, N.Z.)
2024

Evaluating the Efficacy of Conbercept and Dexamethasone Implants Sequentially in the Treatment of Refractory Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO): A One-Year Follow-Up Study.

Clinical ophthalmology (Auckland, N.Z.)
2024

A Case Report on Acute Visual Loss With Ophthalmoplegia Following Spine Surgery.

Cureus
2024

Optic disc edema and visual loss from paracentral acute middle maculopathy mimicking optic neuritis.

Arquivos brasileiros de oftalmologia
2024

Associations between the Vessel Density in Deep Vascular Plexus and Macular Edema Recurrences in Patients with Retinal Vein Occlusion.

Ophthalmic research
2024

Correlation between macular perfusion status and visual acuity in retinal vein occlusion.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2024

APPLICATIONS OF MULTIMODAL GENERATIVE ARTIFICIAL INTELLIGENCE IN A REAL-WORLD RETINA CLINIC SETTING.

Retina (Philadelphia, Pa.)
2024

Integrated Assessment of OCT, Multimodal Imaging, and Cytokine Markers for Predicting Treatment Responses in Retinal Vein Occlusion Associated Macular Edema: A Comparative Review of Anti-VEGF and Steroid Therapies.

Diagnostics (Basel, Switzerland)
2024

Factors Affecting Compliance and Visual Outcomes in Patients Receiving Intravitreal Bevacizumab Injections.

Cureus
2024

Ischemic Central Retinal Vein Occlusion Accompanied by Macular Edema: A Case Report.

Cureus
2024

Impact of high-risk optic disc on central retinal vein occlusion in patients with metabolic disorders.

Frontiers in physiology
2024

Aflibercept for central retinal vein occlusions: long-term outcomes of a 'Treat-and-Extend' regimen.

BMJ open ophthalmology
2024

Atypical Central Retinal Vein Occlusion in an Older Man With Multiple Myeloma: A Case Report.

Ophthalmic surgery, lasers &amp; imaging retina
2024

Oscillatory potential findings in patients with acute ischaemic central retinal vein occlusion.

BMJ open ophthalmology
2024

Demographic profile, prevalence, pattern, and risk factors for retinal vein occlusion in Liberia: A retrospective study.

Oman journal of ophthalmology
2024

GOOD INITIAL VISUAL ACUITY IN PATIENTS WITH MACULAR EDEMA DUE TO RETINAL VEIN OCCLUSION: Management and Outcomes.

Retina (Philadelphia, Pa.)
2024

Longitudinal changes in each retinal layer thickness in patients with non-ischemic central retinal vein occlusion.

Eye and vision (London, England)
2025

Risk Factors for Developing Neovascular Glaucoma in Central Retinal Vein Occlusion: Two-Year Real-World Study.

Ophthalmic epidemiology
2024

Time to initiate anti-vascular endothelial growth factor therapy and visual outcome in central retinal vein occlusion.

Scientific reports
2024

An Unusual Ocular Manifestation of Disseminated Tuberculosis: Combined Retinal Vascular Occlusion Inducing Acute Loss of Vision.

Cureus
2025

Retrospective Cohort Study of Sickle Cell Disease and Large Vessel Retinal Vascular Occlusion Risk in a National United States Database.

Ophthalmology. Retina
2025

Neglected Carotico-cavernous Fistula Causing Central Retinal Vein Occlusion.

Ophthalmology. Retina
2024

Efficacy and Safety of Laser Therapy on Ischemic Central Retinal Vein Occlusion: A Systematic Review and Analysis of Clinical Studies.

Cureus
2024

Case report: A case of unilateral combined central retinal vein occlusion, incomplete central retinal artery occlusion, and papillitis following a third dose of COVID-19 vaccination.

Frontiers in ophthalmology
2024

Case report: CMV retinitis following local and systemic immunosuppression.

Frontiers in ophthalmology
2023

Retinal arterial-venous pulse delay: a new specific marker for a carotid-cavernous fistula.

Frontiers in ophthalmology
2024

Risk of stroke development following retinal vein occlusion: A systematic review and meta-analysis.

Survey of ophthalmology
2024

Central retinal vein occlusion in patients with metastatic solid tumors on tyrosine kinase inhibitors: a report of case series and literature review.

Frontiers in medicine
2025

A case of hyperviscosity syndrome associated with Waldenström macroglobulinemia treated with membrane plasma exchange without predilution.

CEN case reports
2024

Intravitreal Injection of Conbercept Combined with Dexamethasone for Macular Edema Following Central Retinal Vein Occlusion.

Clinical ophthalmology (Auckland, N.Z.)
2024

Concomitant Two-Temporal Cilioretinal Artery Occlusion (CLRAO) With Impending Central Retinal Vein Occlusion (CRVO) in a Young Adolescent With Protein C Deficiency: A Rare Case.

Cureus
2024

The Spectrum of Papillophlebitis.

Ocular immunology and inflammation
2025

Immediate response to intravitreal treatment for macular edema due to diabetes and retinal vein occlusion.

European journal of ophthalmology
2024

Clinical Implications of Alternating Hypointense Bands on OCT Angiography in Retinal Vascular Occlusive Disease.

Ophthalmology. Retina
2025

Finasteride-associated central retinal vein occlusion.

Clinical &amp; experimental optometry
2024

Central Retinal Vein Occlusion in a 28-Year-Old Female Patient: A Case Report.

Klinische Monatsblatter fur Augenheilkunde
2024

Various Ocular Manifestations in Systemic Lupus Erythematosus: A Case Series.

Cureus
2024

Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study.

International journal of ophthalmology
2024

Evaluation of clinical outcomes of raised intraocular pressure following intravitreal triamcinolone acetonide injection.

Romanian journal of ophthalmology
2024

A Multicentric Cross-Sectional Observational Study to Analyze the Effects of Moderate High Altitude on Ocular Health.

Beyoglu eye journal
2024

From Hair Loss to Vision Loss: Minoxidil-Associated CRVO in a Young Female.

Case reports in ophthalmology
2024

Efficacy, Safety, and Treatment Burden of Aflibercept 2 mg and Ranibizumab in Retinal Vein Occlusion: A Systematic Review and Meta-analysis.

Ophthalmology and therapy
2024

Initial response and 12-month outcomes after commencing dexamethasone or vascular endothelial growth factor inhibitors for retinal vein occlusion in the FRB registry.

Scientific reports
2024

Clinical evaluation of ranibizumab and conbercept for the treatment of macular edema secondary to central retinal-vein occlusion.

Asian journal of surgery
2024

Retinal arterial and vein occlusion: is surgery ever indicated?

Current opinion in ophthalmology
2024

Vision-related quality of life in patients with retinal vein occlusion.

International ophthalmology
2024

Infographic: Ranibizumab for macular edema following central retinal vein occlusion (CRUISE).

Eye (London, England)
2024

Homozygous MTHFR C667T carriers ≤45 years old develop central retinal vein occlusion five years earlier than wild type.

Ophthalmic genetics
2024

Changes in wider field swept-source OCT angiography vascular metrics with anti-vascular endothelial growth factor therapy in central retinal vein occlusion.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
2024

Combined Central Retinal Artery Occlusion (CRAO) and Central Retinal Vein Occlusion (CRVO) in a Celiac Disease Patient: A Case Report.

Cureus
2024

Bilateral central retinal vein occlusion following COVID-19 vaccination: Cause or coincidence?

European journal of ophthalmology
2024

Heterogeneity in disease activity, frequency of treatments, and visual outcomes among patients with retinal vein occlusion: relationship between injection need and vision with as-needed ranibizumab.

The British journal of ophthalmology
2023

Role of Novel Inflammatory Factors in Central Retinal Vein Occlusion with Macular Edema.

Medicina (Kaunas, Lithuania)
2023

The progress of assessment methods and treatments of neovascular glaucoma secondary to central retinal vein occlusion.

Frontiers in medicine
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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility.
    Ophthalmology science· 2026· PMID 41693811mais citado
  2. Intravitreal Dexamethasone Implant in Retinal Vein Occlusion: A Pilot Study Exploring Baseline Ocular and Circulating Biomarkers.
    International journal of molecular sciences· 2026· PMID 41596570mais citado
  3. Corrigendum to "Randomized Study of Intravitreal Autologous CD34+ Stem Cells in Central Retinal Vein Occlusion (Treatment of Retinal vein occlusion Using STem cells [TRUST] Report 1): Safety and Feasibility. Ophthalmol Sci. 2026;6:100905".
    Ophthalmology science· 2026· PMID 41584100mais citado
  4. Simultaneous Branch Retinal Artery and Central Retinal Vein Occlusions following Blood Transfusion in a Young Man: A Case Report.
    Case reports in ophthalmology· 2026· PMID 41835312mais citado
  5. [A case of antiphospholipid syndrome complicated with hyperhomocysteinemia presenting initially with central retinal vein occlusion in a young male].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology· 2026· PMID 41820067mais citado
  6. Central retinal vein occlusion in BEST1-related angle-closure glaucoma in autosomal recessive bestrophinopathy: a case report.
    Ophthalmic Genet· 2026· PMID 41987504recente
  7. Hyperbaric Oxygen Therapy Combined With Intravitreal Aflibercept for Combined Retinal Vascular Occlusion in a Young Patient.
    J Vitreoretin Dis· 2026· PMID 41971246recente
  8. Long-term disease control with anti-VEGF treat-and-extend treatment in macular edema due to retinal vein occlusion.
    BMC Ophthalmol· 2026· PMID 41965628recente
  9. Primary optic nerve glioblastoma presenting with clinical features of optic neuritis and central retinal vein occlusion.
    J Fr Ophtalmol· 2026· PMID 41950894recente
  10. Acute Macular Neuroretinopathy in a 27-year-old male patient following impending central retinal vein occlusion.
    Retin Cases Brief Rep· 2026· PMID 41944604recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:411527(Orphanet)
  2. MONDO:0002303(MONDO)
  3. GARD:21734(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q190831(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Oclusão da veia central da retina
Compêndio · Raras BR

Oclusão da veia central da retina

ORPHA:411527 · MONDO:0002303
Prevalência
1-5 / 10 000
Herança
Not applicable
CID-10
H34.8 · Outras oclusões vasculares retinianas
CID-11
Ensaios
3 ativos
Início
Adult, Elderly
Prevalência
28.0 (Europe)
MedGen
UMLS
C0154841
EuropePMC
Wikidata
Papers 10a
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