A Retinopatia Associada ao Câncer (CAR) é uma doença dos olhos. Ela é uma complicação indireta do câncer, que acontece quando há um tumor maligno em outra parte do corpo e o sistema imunológico produz anticorpos que, por engano, atacam as proteínas da retina.
Introdução
O que você precisa saber de cara
A Retinopatia Associada ao Câncer (CAR) é uma doença dos olhos. Ela é uma complicação indireta do câncer, que acontece quando há um tumor maligno em outra parte do corpo e o sistema imunológico produz anticorpos que, por engano, atacam as proteínas da retina.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 12 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 36 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
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Paraneoplastic syndromes and the retina.
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Publicações recentes
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BMC ophthalmologyImmunopathogenesis of ophthalmological paraneoplastic syndromes: Recent findings.
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Surgical case reportsRecovery of outer retinal laminations on optical coherence tomography after treatment of cancer associated retinopathy.
American journal of ophthalmology case reportsUnilateral cancer-associated retinopathy: diagnosis, serology and treatment.
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Frontiers in immunologyAcute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy.
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Journal of glaucomaImprovements of visual function and outer retinal morphology following spontaneous regression of cancer in anti-recoverin cancer-associated retinopathy.
American journal of ophthalmology case reportsExpress of concern on 'Antirecoverin autoantibodies in the patient with non-small cell lung cancer but without cancer-associated retinopathy'.
Lung cancer (Amsterdam, Netherlands)Consensus on the Diagnosis and Management of Nonparaneoplastic Autoimmune Retinopathy Using a Modified Delphi Approach.
American journal of ophthalmologyUnique epitopes for carbonic anhydrase II autoantibodies related to autoimmune retinopathy and cancer-associated retinopathy.
Experimental eye researchGCAP1, Rab6, and HSP27: Novel Autoantibody Targets in Cancer-Associated Retinopathy and Autoimmune Retinopathy.
Translational vision science & technologyParaneoplastic retinopathy associated with occult bladder cancer.
Indian journal of ophthalmologyAutoimmunity in visual loss.
Handbook of clinical neurologyCancer-associated retinopathy as the leading symptom in colon cancer.
Clinical case reportsAryl Hydrocarbon Receptor-Interacting Protein-Like 1 in Cancer-Associated Retinopathy.
OphthalmologyRetinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma.
Journal of ophthalmic inflammation and infectionUnilateral cancer-associated retinopathy: a case report.
Scottish medical journalLarge cell neuroendocrine carcinoma of the lung with cancer-associated retinopathy.
Case reports in oncologySerum inflammatory markers after rupture retinal laser injury in mice.
Ophthalmic surgery, lasers & imaging retinaLatest updates on antiretinal autoantibodies associated with vision loss and breast cancer.
Investigative ophthalmology & visual scienceAssociações
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Comunidades
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Acute and Substantial Vision Loss After Pembrolizumab Immunotherapy for Bladder Cancer.
- Paraneoplastic vitelliform retinopathy successfully treated with intravitreal dexamethasone implants.
- Multimodal Imaging Features of Bilateral Diffuse Uveal Melanocytic Proliferation: A Systematic Review of 82 Patients.
- Paraneoplastic syndromes and the retina.
- Nonparaneoplastic Autoimmune Retinopathy: Scoping Review and Suggested Reporting Guidelines.
- Retinal Transcriptomic Signatures in Sudden Acquired Retinal Degeneration Syndrome (SARDS) and Cancer-Associated Retinopathy (CAR).
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:71505(Orphanet)
- MONDO:0019112(MONDO)
- GARD:18912(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q55082349(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
