Raras
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Síndrome de resistência à insulina tipo B
ORPHA:2298CID-10 · E34.8CID-11 · 5A44DOENÇA RARA

A síndrome de resistência à insulina tipo B pertence ao grupo de síndromes de resistência à insulina muito severa (que inclui condições como leprechaunismo, as lipodistrofias, a síndrome de Rabson-Mendenhall e a síndrome de resistência à insulina tipo A) e acontece quando há um problema no sistema imunológico.

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Introdução

O que você precisa saber de cara

📋

A síndrome de resistência à insulina tipo B pertence ao grupo de síndromes de resistência à insulina muito severa (que inclui condições como leprechaunismo, as lipodistrofias, a síndrome de Rabson-Mendenhall e a síndrome de resistência à insulina tipo A) e acontece quando há um problema no sistema imunológico.

Publicações científicas
1.802 artigos
Último publicado: 2026

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
Adolescent
+ adult, childhood, elderly
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: E34.8
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

📏
Crescimento
11 sintomas
🩸
Sangue
3 sintomas
🧬
Pele e cabelo
3 sintomas
🦴
Ossos e articulações
3 sintomas
🫘
Rins
1 sintomas
🫃
Digestivo
1 sintomas

+ 24 sintomas em outras categorias

Características mais comuns

90%prev.
Hiperglicemia pós-prandial
Muito frequente (99-80%)
90%prev.
Intolerância à glicose
Muito frequente (99-80%)
90%prev.
Hiperinsulinemia de jejum
Muito frequente (99-80%)
90%prev.
Concentração anormal de ácidos graxos circulantes
Muito frequente (99-80%)
90%prev.
Hipotrigliceridemia
Muito frequente (99-80%)
90%prev.
Perda de peso
Muito frequente (99-80%)
50sintomas
Muito frequente (14)
Frequente (19)
Ocasional (17)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 50 características clínicas mais associadas, ordenadas por frequência.

Hiperglicemia pós-prandialPostprandial hyperglycemia
Muito frequente (99-80%)90%
Intolerância à glicoseGlucose intolerance
Muito frequente (99-80%)90%
Hiperinsulinemia de jejumFasting hyperinsulinemia
Muito frequente (99-80%)90%
Concentração anormal de ácidos graxos circulantesAbnormal circulating fatty-acid concentration
Muito frequente (99-80%)90%
HipotrigliceridemiaHypotriglyceridemia
Muito frequente (99-80%)90%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico1.802PubMed
Últimos 10 anos200publicações
Pico2025106 papers
Linha do tempo
2026Hoje · 2026🧪 2005Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
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3Fase 32
·Pré-clínico3
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 5 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Síndrome de resistência à insulina tipo B

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Ensaios clínicos abertos e novidades científicas recentes

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Outros ensaios clínicos

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Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
246 papers (10 anos)
#1

Periodontitis Induces B Cell-Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)2026 Mar 20

A growing consensus indicates that periodontitis (PD) adversely affects glycemic control in type 2 diabetes, though its underlying mechanisms remain unclear. Here, we report that PD, induced by long-term oral ligatures, significantly aggravated hyperglycemia and hepatic gluconeogenesis in high-fat diet-induced obese mice, with its impact on insulin resistance being more pronounced in the liver than in adipose or muscle tissue. Immunologically, PD increased systemic B cell abundance, promoted hepatic B2 cell mobilization, facilitated the expansion of Kupffer cells and adipose tissue macrophages, and activated the NLRP3 inflammasome. Depleting B cells significantly alleviated PD-induced glucose dysregulation, whereas adoptive transfer of B cells from PD mice exacerbated glucose dysregulation and Kupffer cell expansion in Rag1-/- mice. Mechanistically, upregulation of the interleukin (IL)-18 receptor was observed in PD-exposed B cells. IL-18 directly enhanced B cell proliferation, and hepatic macrophages from PD mice secreted elevated levels of IL-18, further driving B cell expansion. Neutralizing IL-18 or depleting macrophages significantly mitigated PD-associated metabolic and B cell abnormalities. Therefore, PD exacerbates hyperglycemia by promoting the pathogenic expansion of B cells and their crosstalk with macrophages via the IL-18 signaling axis. Targeting the NLRP3/IL-18 axis holds promise for preventing glucose dysregulation and aberrant immune cell interactions primed by PD.

#2

African immigrants with type 2 diabetes present with three physiologic subtypes: implications for screening, diagnosis and treatment.

BMJ open diabetes research &amp; care2026 Mar 18

As type 2 diabetes (T2D) prevalence increases in the USA and Africa, factors from both regions affect African immigrants. T2D in African immigrants was characterized by examining: (a) insulin deficiency and insulin resistance; (b) phenotypic presentation; (c) sociodemographic factors. In 633 African immigrants (male: 62%, age 39±11, (mean±SD), range 20-70 years), body mass index (BMI): 27.8±4.6, range 18.8-46.2 kg/m2), weight gain information was collected, BMI and waist circumference (WC) measured and OGTT performed. Insulin resistance was defined by the lowest quartile of the Matsuda Index (≤2.80); insulin secretion by the Insulin Secretion Index (ISI). Insulin deficiency was defined as less than the maximum ISI in participants with T2D without IR (0.430). WC thresholds defined central obesity (men: WC ≥94 cm; women ≥80 cm). Normal glucose tolerance, pre-diabetes and T2D occurred in 61%, 32% and 7%, respectively. Three subtypes of T2D were identified: insulin-deficient-T2D (ID-T2D) in 45%, insulin-resistant-T2D (IR-T2D) in 30%, insulin-deficient+insulin-resistant (ID+IR-T2D) in 25%. ID+IR-T2D had the highest glucose concentrations (all p<0.05), whereas insulins were highest in IR-T2D (all p<0.01). Phenotypic differences by T2D subtype were identified. In the ID-T2D group, 20% of participants had a healthy weight and central obesity occurred in 55%. In the IR-T2D and ID+IR-T2D groups, 100% had central obesity and a BMI in either the overweight or obese categories. Sociodemographic factors specifically, weight gain, sedentary lifestyle and percent married, increased across glucose tolerance category (p values <0.01) but did not differ by T2D subtype (p≥0.3). Spanning the BMI spectrum from normal to obese, African immigrants have three subtypes of T2D. Weight gain was greatest in immigrants who developed T2D but did not differ by subtype. As life in America promotes weight gain, sharing information about the consequences of weight gain with all Americans, both native and foreign-born, is key to T2D prevention and treatment.

#3

A Combined Probiotic-Morus alba Strategy Enhances Glucose Homeostasis in an In Vitro Gut-Pancreas-Liver Axis Model: A Preliminary Mechanistic Screening Study.

International journal of molecular sciences2026 Mar 04

Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder linked to gut microbiota dysbiosis and impaired inter-organ metabolic signalling. This study investigated the combined effects of the probiotic Lactiplantibacillus plantarum TJA7 and Mulberry Leaf extract (Morus alba) on cellular processes relevant to T2DM-related metabolic dysfunction. An advanced in vitro gut-pancreas-liver axis model, using Caco-2, EndoC-βH5, and HepG2 cells, was employed under hyperglycemic and oxidative stress conditions. The combined treatment consistently outperformed the individual components by improving intestinal barrier integrity, as indicated by increased transepithelial electrical resistance (TEER), and by enhancing butyrate translocation across the intestinal layer. Metabolites derived from the combination attenuated pancreatic β-cell dysfunction, reducing reactive oxygen species (ROS) levels and increased insulin secretion (1.7-fold compared with Mulberry Leaf extract alone). At the hepatic level, co-administration modulated key glucose metabolism pathways, including Insulin Receptor Substrate 1 (IRS1), Protein Kinase B (AKT), AMP-Activated Protein Kinase (AMPK), and Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1 Alpha (PGC-1α), suggesting improved cellular glucose handling. Collectively, these findings support a positive dose-specific interaction under the tested conditions and provide a biologically plausible, hypothesis-generating framework for probiotic-phytochemical cooperation along the gut-pancreas-liver axis. Further in vivo and clinical studies are required to establish causality and translational relevance.

#4

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.

Cell metabolism2026 Mar 10

Extracellular vesicles (EVs) are now recognized as potent mediators of inter-organ signaling and are implicated in the pathogenesis of obesity and associated comorbidities. Despite a recent surge in functional information about EVs, we still lack a basic understanding of how endogenous EV levels are controlled to regulate inter-organ signaling. New flow cytometry technologies have allowed us to study the regulation of circulating endogenous EVs from metabolically relevant cell types such as adipocytes (adipocyte-derived EVs [adipoEVs]). We provide evidence for a paradigm of EV regulation in which tissue-resident immune cells, predominantly macrophages, clear EVs released by local tissue cells or those entering the tissue from circulation, an activity that determines circulating EV levels. In obesity, EV uptake by adipose tissue immune cells is reduced, leading to increased circulating adipoEVs and reduced adipoEV clearance rates. This work shows that tissue immune cells gate tissue EV entry into the circulation, making them key regulators of inter-organ EV signaling.

#5

Delayed acute respiratory distress syndrome and sepsis-associated disseminated intravascular coagulation following aluminium phosphide poisoning.

BMJ case reports2026 Mar 06

Aluminium phosphide is a highly lethal pesticide that liberates phosphine gas, leading to mitochondrial dysfunction, distributive shock and cardiotoxicity, but guidance on late pulmonary complications is limited. We report a previously healthy adolescent who ingested ~1.5 g of aluminium phosphide in a suicide attempt and initially presented haemodynamically stable with metabolic acidosis and elevated lactate. By 72-96 hours, she developed progressive hypoxemic respiratory failure with bilateral infiltrates fulfilling Berlin criteria for moderate acute respiratory distress syndrome (ARDS) (PaO₂/FiO₂ nadir ≈115 on FiO₂ 1.0), preceded by fever and culture-proven lower respiratory and urinary tract infections, resulting in sepsis and disseminated intravascular coagulation (DIC). She required escalation from non-invasive to invasive mechanical ventilation, with lung-protective strategies, targeted antibiotics, component therapy for DIC and early magnesium and calcium supplementation. Despite markedly elevated N-terminal pro-B-type natriuretic peptide with preserved biventricular function on echocardiography and transient acute kidney injury, she made a full clinical recovery and was discharged with normal oxygenation and functional status. This case underscores that delayed moderate ARDS with superimposed sepsis and DIC can complicate initially stable aluminium phosphide poisoning and highlights that meticulous, protocol-based supportive care can still result in survival in this rarely reported scenario.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC710 artigos no totalmostrando 199

2026

Implications of Genetic Elements on Type 2 Diabetes Mellitus Pathogenesis and Management.

Endocrinology, diabetes &amp; metabolism
2026

Adipose stem cell-derived exosomes as emerging neurotherapeutics in obesity induced diabetic neuropathy.

Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie
2026

The immunometabolic network in obesity-associated insulin resistance: a systemic multi-organ and multi-cellular perspective.

International immunopharmacology
2026

Association of the triglyceride-glucose index with carotid intima-media thickness in type 2 diabetes: effect modification by age and albuminuria-a retrospective cross-sectional study.

Frontiers in cardiovascular medicine
2026

Periodontitis Induces B Cell-Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026

African immigrants with type 2 diabetes present with three physiologic subtypes: implications for screening, diagnosis and treatment.

BMJ open diabetes research &amp; care
2026

Is it possible for type 2 diabetic patients with low level of copper to have better glycemic control under different apolipoprotein B levels?

Frontiers in endocrinology
2026

Gentiopicroside alleviates type 2 diabetes mellitus by attenuating oxidative stress and reshaping gut microbiota in high-fat diet and streptozotocin-induced mice.

Frontiers in nutrition
2026

Association of Monocyte Chemoattractant Protein-1 and Endothelin-1 Genes with Cardiac Pro-Β-Type Natriuretic Peptide Levels in Obese Hypertensive Patients.

Current pharmaceutical design
2026

Cannabisin A and B from hemp seed hulls improve glucose homeostasis by re-engaging insulin, leptin, and AMPK pathways via selective PTP1B inhibition.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2026

A Combined Probiotic-Morus alba Strategy Enhances Glucose Homeostasis in an In Vitro Gut-Pancreas-Liver Axis Model: A Preliminary Mechanistic Screening Study.

International journal of molecular sciences
2026

A system biology-based identification of potential biomarker interlinking the effect of anti-diabetic drug, Metformin, on reduced occurrence of hepatocellular carcinoma.

Journal of diabetes and metabolic disorders
2026

MYC-positive follicular lymphoma complicated by refractory lactate and clonal evolution: a case report.

Frontiers in oncology
2026

[Guidelines for the diagnosis and treatment of obstructive sleep apnea in adults (2025)].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
2026

[Study on mechanisms of "Huangqi-Shengdihuang-Shanyao" in treating type 2 diabetes based on network pharmacology and experimental verification].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
2026

Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.

Cell metabolism
2026

Study of association between serum anti-Müllerian hormone, glucose intolerance, and metabolic syndrome in women with polycystic ovarian syndrome: A comparative study.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2026

IL-27 Aggravates Sepsis-Induced ARDS by Driving Macrophage Ferroptosis Through Activation of NCOA4-Mediated Ferritinophagy.

Journal of inflammation research
2026

Type 2 diabetes subphenotypes are associated with differential outcomes after metabolic and bariatric surgery: An international multicentre retrospective cohort study.

Diabetes, obesity &amp; metabolism
2026

Delayed acute respiratory distress syndrome and sepsis-associated disseminated intravascular coagulation following aluminium phosphide poisoning.

BMJ case reports
2026

Mechanistic insights into the regulation of glucose‒lipid metabolism by the bioactive constituents of ginseng.

Journal of ginseng research
2026

Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders.

Environmental pollution (Barking, Essex : 1987)
2026

Development and characterization of a model of mucopolysaccharidosis type IVA for evaluating therapies targeting bone disease.

Disease models &amp; mechanisms
2026

The role of COPD and inhaled corticosteroids in major adverse cardiovascular events in cardiovascular-kidney-metabolic populations.

BMC medicine
2026

Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome.

Nature communications
2026

Atypical diabetes subtypes in Black African populations.

Diabetologia
2025

Determination of Insulin Resistance, β-cell Function and Insulin Sensitivity Using Modified Homeostatic Model Assessment in Diabetic Rats Treated with Melatonin.

Archives of Razi Institute
2026

Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a systematic review and meta-analyses.

EClinicalMedicine
2026

Hypoglycemia secondary to type B insulin resistance syndrome.

JCEM case reports
2026

Dementia Risk According to Indices of Insulin Sensitivity and Beta-Cell Function in Individuals With Newly Diagnosed Type 2 Diabetes: A Cohort Study.

European journal of neurology
2026

Gut Microbiome-Associated Effects of Plant-Based Diets on Glucose Homeostasis, Body Composition, and Cognitive Function: A Scoping Review.

Advances in nutrition (Bethesda, Md.)
2026

Gut microbiota-mediated branched-chain amino acid metabolism: A novel mechanism by which Bacteroides uniformis improves type 2 diabetes mellitus.

Diabetes, obesity &amp; metabolism
2025

The Modulatory Effects of Bacteroides thetaiotaomicron on Metabolic Parameters, Expression of Diabetes- and Inflammation-Related Genes and Gut Microbiota Composition in a Male Rat Model of Type 2 Diabetes Mellitus.

International journal of endocrinology and metabolism
2026

[Refractory DLBCL to a polatuzumab-containing regimen: efficacy of CAR-T therapy in second line with radiotherapy bridging].

Recenti progressi in medicina
2026

Failure of podocalyxin suppression and HOXA10/HOXA11 activation characterizes endometrial dysfunction in hyperandrogenic PCOS.

Molecular and cellular endocrinology
2026

Genome-Wide Association Study (GWAS)-Derived Type 2 Diabetes Risk Variants in Gestational Diabetes Mellitus: Evidence From North India.

Cureus
2026

Rheumatologic Manifestations of Patients With Type B Insulin Resistance.

Arthritis care &amp; research
2026

Causal role of genetically predicted impairment of branched-chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes.

Diabetes, obesity &amp; metabolism
2026

Eicosapentaenoic Acid Attenuates Type 2 Diabetes Mellitus-Related Sarcopenia in Mice and Its Potential Mechanisms.

Journal of agricultural and food chemistry
2026

The AGE-RAGE Pathway in Endometriosis: A Focused Mechanistic Review and Structured Evidence Map.

International journal of molecular sciences
2026

Fermented Red Ginseng Restores Age-Associated Insulin Homeostasis and Gut Microbiome Balance in Mice.

Biology
2025

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease.

iMetaOmics
2026

Severity of MASH Activity by Iron-Corrected MRI Predicts Insulin Resistance and Cardiometabolic Risk in Type 2 Diabetes.

The Journal of clinical endocrinology and metabolism
2026

Combined Triglyceride-Glucose and Triglyceride-Glucose-Body Mass Index with B-Type Natriuretic Peptide for Enhanced Prediction of Major Adverse Cardiovascular Events in ST-Elevation Myocardial Infarction Patients: A Retrospective Cohort Study.

Reviews in cardiovascular medicine
2025

Mechanisms of gypenosides in type 2 diabetes mellitus via regulation of m6A methylase METTL3/14 and demethylase FTO.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2026

Interleukin-10 expressing B lineage cells in visceral adipose tissue protect against aging-related insulin resistance and extend lifespan.

Nature communications
2026

Pathophysiological Risk Factors Preceding Incidence of Type 2 Diabetes Subtypes: A Pooled Cohort Study in the United States.

Diabetes care
2026

Alpha-Lipoic Acid Reduces NLRP3/ASC Expression and IL-1β Release in Kupffer Cells and Improves Insulin Signaling in FL83B Hepatocytes Exposed to a Conditioned Medium.

Food science &amp; nutrition
2025

Effect of lithium on glucose homeostasis: Role of protein kinase B (AKT) in rats.

Open veterinary journal
2026

Integrating metabolomics, network pharmacology and molecular dynamics simulations reveals that Xiehuang San targets CLCF1-STAT3 to restore insulin signaling in T2DM.

Journal of ethnopharmacology
2026

Metabolic Dysregulation in Laminopathies: Implications for Heart Failure and Cardiac Health.

Current heart failure reports
2025

Insulin-like growth factor 1 (IGF-1)-induced changes in cardiac inducible nitric oxide synthase (iNOS) in obese rats.

Frontiers in endocrinology
2025

Pasteurized Bacteroides thetaiotaomicron and its extracellular vesicles improve metabolic profiles, expression of genes associated with diabetes and inflammation, and gut microbiota in type 2 diabetic rats.

EXCLI journal
2026

Immunoglobulin A-producing cells mediate the clinical benefits of metformin via interleukin-10.

Cell reports
2025

First-Degree Family History of Type 2 Diabetes Mellitus Strengthens the Agreement Between MetS-IR and HOMA-IR in Non-Diabetic Adults.

Pakistan journal of biological sciences : PJBS
2026

Novel Homozygous Variants in CIDEC and WRN in a Young Female with Lipodystrophy and Thyroid Cancer.

International journal of molecular sciences
2026

Lycopene's Role in Mitigating Obesity-Induced Cardiac Remodeling: Insights Into Inflammatory and MMP-2 Pathways.

Molecular nutrition &amp; food research
2026

Evaluation of Gustatory and Olfactory Perception in Type II Diabetic Patients - A Clinical Observational Study.

Annals of African medicine
2026

The CDKN2A/B rs10811661 polymorphism is associated with metabolic syndrome, insulin resistance, and lipid levels in individuals with obesity and impaired fasting glucose.

Clinical biochemistry
2026

Bridging Glycemic and Lipid Control: Effects of Dapagliflozin in Co-Morbid Diabetes and Heart Failure - A Randomized Controlled Trial.

Endocrine, metabolic &amp; immune disorders drug targets
2026

Longitudinal associations of long-term exposure to ambient air pollution, residential greenness, and air temperature with type 2 diabetes subphenotypes: Results from the KORA cohort study.

Environment international
2026

Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion.

EBioMedicine
2026

A pitfall in diagnosing type B insulin resistance syndrome: Suspected antibody interference in a patient with insulin allergy.

Journal of diabetes investigation
2026

Accuracy of Dexcom One+ in Patients with Diabetes or Stress Hyperglycemia Hospitalized in Cardiac Intensive Care Unit.

Diabetes technology &amp; therapeutics
2025

Research progress on oral glucagon-like peptide-1 receptor agonists in the treatment of diabetes mellitus type 2.

Frontiers in molecular biosciences
2026

Insight into Molecular Mechanisms and Pathways Related to the Association of Periodontal Disease and Type 2 Diabetes Mellitus.

Endocrine, metabolic &amp; immune disorders drug targets
2026

Mechanistic insights into psoriasis and type 2 diabetes mellitus comorbidity - Implications for treatment: A review.

Biomolecules &amp; biomedicine
2026

Personalizing bariatric metabolic surgery: Predictors of weight-loss success and risk of weight recurrence.

Metabolism: clinical and experimental
2026

Synergistic Therapeutic Potential of Curcumin and Metformin: a Multipathway Approach to Disease Management.

The Journal of nutrition
2025

[Experience of using mineral waters in patients with type 1 diabetes mellitus for the correction of endotoxinemia].

Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
2026

Association Between Pancreatic β-Cell Function and Quantitative OCT Angiography Metrics in Patients with Type 2 Diabetes Without Clinical Diabetic Retinopathy.

Current eye research
2026

Targeting CD44-Hyaluronic Acid Signalling in Obesity Treatment: Insights from Small Molecules and Nanobioconjugates.

Nutrition and metabolic insights
2026

Insulin Receptor Family Autoantibodies in Patients with Type B insulin Resistance.

The Journal of clinical endocrinology and metabolism
2026

Cardiac vagal activity is associated with insulin metabolism in heart failure: Results from the Myovasc study.

Cardiovascular diabetology
2026

Jiangtang Tiaozhi formula improves obesity and insulin resistance by inhibiting skeletal muscle inflammation and pyroptosis in diet-induced obese mice.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2026

Impact of AKR1C2 and AKR1C3 single-nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity.

American journal of physiology. Endocrinology and metabolism
2025

Alpha-ketoglutarate supplementation improves hyperglycemia and attenuates the decrease in GLUT4 and PGC-1α proteins in adipose tissue of streptozotocin-high-fat diet-induced diabetic mice.

Journal of nutritional science
2026

Improvement of respiratory function with acetazolamide in heart failure: a case of cardio-renal pulmonary syndrome.

Future cardiology
2026

Insulin resistance is associated with incident prediabetes and type 2 diabetes in normoglycemic individuals.

Diabetes &amp; metabolic syndrome
2026

Exogenous Insulin Antibody Syndrome and Subsequent Severe Subcutaneous Insulin Resistance Complicating Type 1 Diabetes.

JCEM case reports
2025

Shared Gut Microbial and Functional Signatures Linking Parkinson's Disease and Type 2 Diabetes Revealed by Function-Anchored Metagenomics.

Microorganisms
2025

In Silico Hypothesis Testing in Drug Discovery: Using Quantitative Systems Pharmacology Modeling to Evaluate the Therapeutic Value of Proinsulin Conversion to Insulin Therapy for Type 2 Diabetes Mellitus.

Pharmaceutics
2025

The Prevalence of H. pylori Among Jordanian Type 2 Diabetic Patients and Its Association with ABO Blood Group.

Medicina (Kaunas, Lithuania)
2025

Prevalence of Cardiovascular-Kidney-Metabolic (CKM) Syndrome in Lithuanian Adults: Insights from a Nationwide Real-World Study Using Electronic Health Records.

Medicina (Kaunas, Lithuania)
2025

Pharmacological Inhibition of Pyruvate Dehydrogenase Kinase 4 Enhances Insulin Sensitivity in Mouse Models of Diabetes and Obesity.

Journal of obesity &amp; metabolic syndrome
2025

Beyond HOMA-IR: Comparative Evaluation of Insulin Resistance and Anthropometric Indices Across Prediabetes and Type 2 Diabetes Mellitus in Metabolic Syndrome Patients.

Life (Basel, Switzerland)
2025

The Effect of Semaglutide on Pancreatic β-Cell Function in Adults with Type 2 Diabetes: A Systematic Review and Meta-Analysis.

Journal of clinical medicine
2025

Targeting the TLR4 axis with microbiota-oriented interventions and innovations in diabetes therapy: a narrative review.

Frontiers in immunology
2026

Targeted Next-Generation Sequencing of the Leptin-Melanocortin Pathway in Severe Obesity.

Obesity (Silver Spring, Md.)
2026

Long-term remission of type B insulin resistance syndrome with immunotherapy: A case report.

Journal of diabetes investigation
2025

Beyond Traditional Risk Factors: Inflammation, Asymmetric Dimethylarginine, and N-Terminal pro-B-Type Natriuretic Peptide Predict Cardiovascular Risk in Chronic Kidney Disease.

Cureus
2025

Unraveling the Association Between Novel Lipid Biomarkers and Metabolic Syndrome: A Cross-Sectional Study.

Cureus
2025

[Electroacupuncture ameliorates skeletal muscle insulin resistance in diabetic rats via PPAR-γ/NF-κB signaling pathway].

Zhen ci yan jiu = Acupuncture research
2025

MAFLD in Vietnam: a neglected public health challenge requiring urgent policy action.

Frontiers in clinical diabetes and healthcare
2025

The effect of a sustainable diet and time-restricted eating and probiotic in heart failure with reduced ejection fraction patients: study protocol for a randomized, double-blind, and placebo-controlled trial.

Nutrition journal
2026

Oligosaccharides ameliorate insulin resistance and hepatic metabolism by promoting the leptin/POMC axis to accelerate short stature growth and development.

Tissue &amp; cell
2025

Restorative Potential of Stevia Leaves Against Cardiomyopathy Associated with Type 2 Diabetes Through Multiple Interdependent Pathways.

Pakistan journal of biological sciences : PJBS
2025

A Case of Grade 4 Hyperglycemia Induced by Capivasertib and Successfully Managed with Early Insulin Intervention.

Surgical case reports
2025

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole-Blood RNA Transcriptome.

Arthritis &amp; rheumatology (Hoboken, N.J.)
2025

Antidiabetic Activity of Amaranthus hybridus Leaf-based Diet in High-fat Diet and Streptozotocin-induced Diabetic Rats.

Plant foods for human nutrition (Dordrecht, Netherlands)
2025

Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials.

Frontiers in nutrition
2025

Evaluation of Serum Insulin-Like Growth Factor 1 (IGF-1) Among Controlled and Uncontrolled Type 2 Diabetes Mellitus in a Geriatric Population From North India.

Cureus
2026

High-Protein Diet Exacerbates Insulin Resistance via the JNK/IKKβ-IRS-1 Pathway.

Endocrinology, diabetes &amp; metabolism
2026

Cross-species studies implicate the melanocortin 3 receptor more strongly in the control of pubertal development than energy balance.

Molecular metabolism
2025

[Biochemical markers of stress in medical workers with occupational burnout syndrome and their dynamics in the application of physiotherapeutic factors].

Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury
2025

Medical nutrition therapy in obesity management.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
2025

Vaccinium oldhamii fruits improve insulin resistance by inhibiting inflammation in macrophages and adipocytes.

Nutrition research and practice
2025

Metabolic crossroads in insulin resistance: exploring lipid dysregulation and inflammation.

Frontiers in immunology
2025

Microbial Metabolite, Macro Impact: Urolithin A in the Nexus of Insulin Resistance and Colorectal Tumorigenesis.

Nutrients
2025

Natriuretic Peptides as Multisystem Regulators: From Clinical Biomarkers to Therapeutic Targets in Cardio-immunology.

Cardiovascular drugs and therapy
2026

Integration of BNP and blood glucose for identifying coronary flow reserve impairment: A cardiovascular-kidney-metabolic perspective.

American heart journal plus : cardiology research and practice
2026

Innate immune-cell-derived BAFF promotes inflammatory response of ICOSL⁺ B cells via non-canonical NF-κB in diabetic autoimmunity.

Molecular therapy : the journal of the American Society of Gene Therapy
2026

Transcriptomic analysis reveals metabolic changes in the liver, subcutaneous adipose, and mammary gland tissues during the process of conjugated linoleic acid-induced milk fat depression in dairy cows.

Journal of dairy science
2025

Dill extract attenuates liver fibrosis and steatohepatitis in obese rats via modulating TGF-β1 signaling and collagen accumulation.

Research in pharmaceutical sciences
2026

Eleutheroside B liposomes ameliorate type 2 diabetes mellitus by modulating glucose and lipid metabolism: A metabolomic study.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2026

Electroacupuncture modulates myocardial insulin signaling and inflammatory markers in a rat model of type 2 diabetes.

Acupuncture in medicine : journal of the British Medical Acupuncture Society
2025

Butyrate-Mediated Upregulation of Insulin Pathway Gene Expression Suggests Potential Antidiabetic Effects.

Drug development research
2026

Systematic Review: Efficacy, Safety and Metabolic Outcomes of GLP-1 Receptor Agonists in Inflammatory Bowel Disease.

Alimentary pharmacology &amp; therapeutics
2025

Sparstolonin B and Curcumin alleviate atherogenesis by modulating T helper 17-stromal cell interactions associated with interleukin-17 receptor A (IL-17RA) - transforming growth factor-β-activated kinase 1 (TAK1) - nuclear factor-kappa B (NF-κB) signaling.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2025

Post-PCI Inflammation and Diastolic Dysfunction in Patients with Metabolic Risk Factors: A Retrospective Observational Study.

Medicina (Kaunas, Lithuania)
2025

Combined Oral Contraceptives and the Risk of Thrombosis.

International journal of molecular sciences
2026

Regulatory effects of polysaccharides from Houttuynia cordata Thunb. on gut microbiota and hyperglycemia in type 2 diabetes mellitus mice.

International journal of biological macromolecules
2026

Effects of Marked Weight Loss Induced by Gastric Bypass Surgery or Low-Calorie Diet Alone on Postprandial Glucose Disposal in Type 2 Diabetes.

Diabetes
2025

Riboflavin Transporter Deficiency as a Cause of Progressive Encephalopathy.

Metabolites
2026

A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice.

Diabetes, obesity &amp; metabolism
2025

Age-stratified Characterization of Body Composition and Biochemical Profiles in Cardiometabolic Risk Assessment.

Medical archives (Sarajevo, Bosnia and Herzegovina)
2025

Inverse directions of association of higher physical activity and higher insulin resistance with human skeletal muscle cell type abundance and fiber-type-level gene expression.

bioRxiv : the preprint server for biology
2025

Fructose and follistatin potentiate acute MASLD during complete hepatic insulin resistance.

Nature communications
2026

The muscle-brain axis in type 2 diabetes: Molecular pathways linking sarcopenia and cognitive decline.

Ageing research reviews
2025

Mechanism of action and research advancements of Qi-tonifying traditional Chinese medicine in the treatment of type 2 diabetic mellitus.

American journal of translational research
2025

Recent Applications of Disulfide Bond-Containing Compounds in Medicinal and Agrochemical Chemistry.

Journal of agricultural and food chemistry
2025

Sex Differences in the Characteristics of Acute Aortic Dissection: Stanford Type A Dissection among Elderly Women in Japan.

Juntendo medical journal
2026

MRI Analysis of Cardiac Fat, Abdominal Adiposity and Cardiac Function After Vertical Sleeve Gastrectomy in Youth With Type 2 Diabetes.

Pediatric obesity
2026

Impact of RAS/BRAFV600E Mutations on the Tumor Immune Microenvironment in Mismatch Repair-Deficient/Microsatellite Instability Colorectal Cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research
2026

The miR-200 family in type 2 diabetes: therapeutic and biomarker perspectives.

Journal of diabetes and its complications
2025

Apremilast attenuates hepatic steatosis and metabolic dysfunction in a murine model of MASLD: Implications for patients with Psoriatic disease.

Biomedicine &amp; pharmacotherapy = Biomedecine &amp; pharmacotherapie
2025

Key Signals Produced by Gut Microbiota Associated with Metabolic Syndrome, Cancer, Cardiovascular Diseases, and Brain Functions.

International journal of molecular sciences
2025

LncRNA SOX2OT improves insulin resistance in type 2 diabetes with sleep disorders by activating IRS/PI3K/AKT and suppressing oxidative stress and inflammation through the miR-552-5p/SOX2 axis.

General physiology and biophysics
2025

Prevalence of polycystic ovary syndrome (PCOS) and its associated hormonal and comorbid risk factors in Northeast India: a cross-sectional comparative study.

Therapeutic advances in reproductive health
2025

Recent Advancements in Known and Emerging Risk Factors of Hepatocellular Carcinoma.

Cancer medicine
2025

Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.

Chinese journal of integrative medicine
2026

Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study.

Diabetologia
2025

Role of FGF21 in Heart Failure: Molecular Insights and Therapeutic Implications.

Cardiology in review
2025

Delirium as an Atypical Presentation of Severe Aortic Stenosis in a Cognitively Intact Nonagenarian With Atrial Fibrillation: A Case Report.

Cureus
2026

N-terminal pro B-type natriuretic peptide increase after bariatric surgery is linked to decreased insulin resistance and is more pronounced in women.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
2025

Chrysin Alters Hypothalamic Levels of Proteins Related to Appetite and Sweet Taste Preferences in Fructose-Fed Rats.

The Journal of nutrition
2025

GLP-1 receptor agonists and inflammatory pathway modulation: Dual targeting of metabolic and immune dysfunction in insulin resistance.

Biochemical and biophysical research communications
2025

All-Trans Retinoic Acid Attenuates Inflammation and Insulin Resistance Induced by Adipocyte-Macrophage Coculture.

Molecules (Basel, Switzerland)
2025

Exploring the Mechanisms of n-Butanol Extract from Tibetan Medicine Biebersteinia heterostemon in Improving Type 2 Diabetes Based on Network Pharmacology and Cellular Experiments.

International journal of molecular sciences
2025

ApolipoproteinB48 Knockout Ameliorates High-Fat-Diet-Induced Metabolic Impairment in Mice.

Biomolecules
2025

Interferons in Autoimmunity: From Loss of Tolerance to Chronic Inflammation.

Biomedicines
2025

Fibrosis Severity in MASLD Determines the Predictive Value of Lp-PLA2 for Carotid Atherosclerosis in Type 2 Diabetes: A Cross-Sectional Study.

Biomedicines
2025

Exploring Genetic Heterogeneity in Type 2 Diabetes Subtypes.

Genes
2025

Mechanisms of Dangguiliuhuang Tang in Streptozotocin-Induced Type 2 Diabetes Mellitus Mice Based on Network Pharmacology, Gut Microbiota, and Experimental Validation.

Diabetes, metabolic syndrome and obesity : targets and therapy
2025

Management of dyslipidaemia in patients with comorbidities: facing the challenge: type 2 diabetes mellitus.

European heart journal. Cardiovascular pharmacotherapy
2025

HOMA-AD, inflammation, and adipose tissue dysfunction as key drivers of immunometabolic risk in people living with HIV and type 2 diabetes.

Frontiers in endocrinology
2025

Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.

Frontiers in nutrition
2026

LGALS3BP Induces Insulin Resistance via TLR2-IKKα/β Pathway-Mediated IRS1 Serine Phosphorylation.

Endocrinology and metabolism (Seoul, Korea)
2025

The Comparison Between Dietary Vitamin A Deficiency and the CRP Level in Alzheimer's Disease in Patients with Type 2 Diabetes: A Case-Control Study.

Current Alzheimer research
2025

Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation.

Cell reports
2025

Chromium Mitigates the Iron-Induced Glucose Metabolism Disorder via the PI3K/Akt/Bcl-2 Signaling Pathway: An In Vivo Study in Wistar Rats.

Biological trace element research
2025

Beta-Cell Secretory Function in Recent-Onset Type 2 Diabetes Mellitus: A Comparative Study Across Body Mass Index Categories.

Cureus
2025

Idiopathic Sclerochoroidal Calcification With a Concurrent COL11A2 Variant: A Case Report.

Cureus
2025

Evaluating the utility of growth differentiation factor 15 and fibroblast growth factor 21 as blood biomarkers for Rett syndrome.

Scientific reports
2026

Type B Insulin Resistance: A Case Report of a Rare Complication of Systemic Lupus Erythematosus.

The Journal of rheumatology
2025

Coptidis rhizoma ameliorates type 2 diabetes mellitus-related metabolic dysfunction-associated steatohepatitis by downregulating the IL-17RA/NF-κB signaling pathway.

Frontiers in pharmacology
2025

Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan.

Cell reports
2025

Insulin Resistance and Beta-Cell Function in the Context of Dyslipidemia in a Non-obese Indian Population With Type 2 Diabetes.

Cureus
2025

Hypoglycemic potential of American ginseng saponins: inhibition of α-amylase and improvement of insulin resistance.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
2026

Functional food potential of Anoectochilus roxburghii aqueous extract: UPLC-MS profiling and in vivo efficacy in type 2 diabetic mice.

Journal of the science of food and agriculture
2025

Relationship Between Metabolic and Histological Responses in People With Metabolic Dysfunction- Associated Steatohepatitis With and Without Type 2 Diabetes: Participant-Level Exploratory Analysis of the SYNERGY-NASH Trial With Tirzepatide.

Diabetes care
2025

Traditional Chinese medicine acupoint pasting for preventing and treating gastrointestinal reactions in type II diabetes mellitus patients undergoing glucagon-like peptide-1 receptor agonist therapy: A clinical study.

Journal of medical biochemistry
2025

Prevalence and Risk Factors of Metabolic-Associated Fatty Liver Disease in the Korean Air Force.

Aerospace medicine and human performance
2025

Inflammation Mediates the Associations Between Selenium Status and Glucose Metabolism in Chinese Females Over 45 Years Old: a National Cross-Sectional Study.

Biological trace element research
2025

A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults.

Nature medicine
2025

Congestion and Low Cardiac Output Hemodynamic Phenotype Drives Outcomes in Overweight and Obese HFpEF.

JACC. Heart failure
2025

Cytokeratin 8 as a Novel Therapeutic Target in Type 2 Diabetes Mellitus: Suppression of Hepatic Glycogen Synthesis via IRS1/PI3K/Akt/GSK3β Signaling.

Current drug targets
2025

The relationship between genotype and phenotype in Chinese children with glucose transporter type 1 deficiency syndrome.

Frontiers in neurology
2025

Efficacy of probiotic co-supplementation with omega-3 PUFAs on pancreatic beta-cell function in type 2 diabetes.

Scientific reports
2025

Effect of Bariatric Surgery on the Apolipoprotein B/Apolipoprotein A1 Ratio and Insulin Resistance.

Obesity surgery
2026

Differential modulation of adipose tissue insulin resistance by modified traditional Japanese diet and SGLT-2 inhibitor canagliflozin in type 2 diabetes.

Naunyn-Schmiedeberg's archives of pharmacology
2025

Assessment of Clinical Profile and Biochemical Parameters in Diverse Phenotypes of Polycystic Ovarian Syndrome.

Mymensingh medical journal : MMJ
2025

Activin receptor type IIA/IIB blockade increases muscle mass and strength, but compromises glycemic control in mice.

Molecular metabolism
2025

Cholesterol-driven pathological astrocytic responses in diabetes-associated cognitive impairment through astrocytic SCAP accumulation and NF-κB-C3 signaling modulation.

Experimental &amp; molecular medicine
2025

Metformin-loaded Chitosan nanoparticles alleviate insulin resistance in the polycystic ovarian syndrome rat model through modulation of PI3K/AKT/ GLUT4 in ovarian tissue.

Reproductive biology
2025

Oral lipoteichoic and lipoic acids improve insulin resistance and body composition in porphyria mice on a high-carbohydrate diet.

Journal of physiology and biochemistry
2025

Single-cell transcriptomics reveals apolipoprotein A4-mediated metabolic-immune reprogramming in lymphocytes during early obesity-related chronic kidney disease.

Acta biochimica et biophysica Sinica
2025

Case Report: Primary pulmonary lymphoma with CT negative and PET high metabolism combined with hemophagocytic syndrome.

Frontiers in medicine
2025

The Beneficial Effect of Lycium barbarum Polysaccharides on Insulin Resistance and Hepatic Glucose Production in Diabetes.

Analytical cellular pathology (Amsterdam)
2025

Modulation of hyperglycemia, insulin resistance responses and gut microbiota composition in type 2 diabetic mice by capsicum residue soluble dietary fiber.

Food &amp; function
2025

Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.

Communications biology
2025

Associations of triglyceride-glucose index with N-terminal pro-B-type natriuretic peptide and mortality in middle-aged and elderly individuals.

Frontiers in endocrinology
2025

Targeting Insulin Resistance in Hepatocytes: A Novel Insulin-Mimetic Agent Delivered via an Advanced Nanocarrier System.

ACS pharmacology &amp; translational science
2025

Adipocyte-specific ETB receptor overexpression induces obesity, insulin resistance, and dyslipidemia in high-fat diet-fed female mice.

Physiological reports
2025

Severe Insulin Resistance: Diagnosis and Management.

Current diabetes reviews
2026

Clinical risk phenotypes in diabetes and their associations with adverse cardiovascular events: A report from the Silesia Diabetes-Heart Project.

Diabetic medicine : a journal of the British Diabetic Association
2025

[Electroacupuncture improves glucose and lipid metabolism disorders in diabetic obese rats via PI3K/Akt/GLUT4 pathway].

Zhen ci yan jiu = Acupuncture research
2025

Alterations in glucocorticoid homeostasis following sleeve gastrectomy.

bioRxiv : the preprint server for biology
2025

Innovative insights into the effects of a high-sucrose diet on pancreatic health and the therapeutic role of empagliflozin in type 2 diabetes: An experimental study.

Animal models and experimental medicine
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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Periodontitis Induces B Cell-Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany)· 2026· PMID 41858253mais citado
  2. African immigrants with type 2 diabetes present with three physiologic subtypes: implications for screening, diagnosis and treatment.
    BMJ open diabetes research &amp; care· 2026· PMID 41850717mais citado
  3. A Combined Probiotic-Morus alba Strategy Enhances Glucose Homeostasis in an In Vitro Gut-Pancreas-Liver Axis Model: A Preliminary Mechanistic Screening Study.
    International journal of molecular sciences· 2026· PMID 41828592mais citado
  4. Immune cells regulate circulating adipocyte extracellular vesicle levels in response to metabolic shifts.
    Cell metabolism· 2026· PMID 41812649mais citado
  5. Delayed acute respiratory distress syndrome and sepsis-associated disseminated intravascular coagulation following aluminium phosphide poisoning.
    BMJ case reports· 2026· PMID 41791773mais citado
  6. Metabolic syndrome and the risk of perioperative ischemic stroke in non-cardiac surgery: a case-control retrospective study.
    Front Endocrinol (Lausanne)· 2026· PMID 41890192recente
  7. Hypoglycemia secondary to type B insulin resistance syndrome.
    JCEM Case Rep· 2026· PMID 41767203recente
  8. Study of Clinical Profile of Patients of Nonalcoholic Fatty Liver Disease and Its Correlation with Metabolic Syndrome.
    Ann Afr Med· 2026· PMID 41587875recente
  9. A pitfall in diagnosing type B insulin resistance syndrome: Suspected antibody interference in a patient with insulin allergy.
    J Diabetes Investig· 2026· PMID 41574820recente
  10. Long-term remission of type B insulin resistance syndrome with immunotherapy: A case report.
    J Diabetes Investig· 2026· PMID 41451857recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:2298(Orphanet)
  2. MONDO:0016464(MONDO)
  3. GARD:3009(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q29982026(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Síndrome de resistência à insulina tipo B
Compêndio · Raras BR

Síndrome de resistência à insulina tipo B

ORPHA:2298 · MONDO:0016464
Prevalência
Unknown
Herança
Not applicable
CID-10
E34.8 · Outros transtornos endócrinos especificados
CID-11
Início
Adolescent, Adult, Childhood, Elderly
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0342337
EuropePMC
Wikidata
Papers 10a
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