A síndrome POEMS é uma síndrome paraneoplásica caracterizada por polirradiculoneuropatia (P), organomegalia (O), endocrinopatia (E), distúrbio clonal de células plasmáticas (M) e alterações cutâneas (S). Outras características incluem papiledema, sobrecarga de volume extravascular, lesões ósseas escleróticas, trombocitose/eritrocitose e níveis elevados de VEGF.
Introdução
O que você precisa saber de cara
A síndrome POEMS é uma síndrome paraneoplásica caracterizada por polirradiculoneuropatia (P), organomegalia (O), endocrinopatia (E), distúrbio clonal de células plasmáticas (M) e alterações cutâneas (S). Outras características incluem papiledema, sobrecarga de volume extravascular, lesões ósseas escleróticas, trombocitose/eritrocitose e níveis elevados de VEGF.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Entender a doença
Do básico ao detalhe, leia no seu ritmo
Preparando trilha educativa...
Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
+ 20 sintomas em outras categorias
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 51 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
Encontrou um erro ou informação desatualizada? Sugira uma correção →
Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Síndrome POEMS
Selecione um estado ou use sua localização para ver resultados.
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
🟢 Recrutando agora
3 pesquisas recrutando participantes. Converse com seu médico sobre a possibilidade de participar.
Outros ensaios clínicos
17 ensaios clínicos encontrados, 5 ativos.
Publicações mais relevantes
Mostrando amostra de 200 publicações de um total de 632
POEMS syndrome: a neuromuscular perspective.
Polyneuropathy, Organomegaly, Endocrinopathy, M-protein and Skin changes (POEMS) syndrome is a rare multisystemic disorder associated with plasma cell dyscrasia, most commonly presenting with peripheral neuropathy. Due to its complex and heterogeneous clinical presentation, misdiagnosis is frequent, particularly with chronic inflammatory demyelinating polyradiculoneuropathy, which often leads to delays in appropriate management. Peripheral nerve involvement in POEMS syndrome is predominantly demyelinating, typically accompanied by early axonal degeneration. Specific clinical, neurophysiological and imaging features are key to differentiating POEMS from other acquired demyelinating neuropathies. Elevated levels of vascular endothelial growth factor (VEGF) play a central role in its pathophysiology, promoting disruption of the blood-nerve barrier and contributing to the systemic manifestations. Accurate diagnosis requires a multidisciplinary approach and is often supported by laboratory testing, including VEGF measurement and monoclonal protein screening as well as advanced imaging techniques. Therapeutic strategies are guided by disease extent and include radiotherapy for localised lesions, systemic chemotherapy and autologous haematopoietic stem cell transplantation for disseminated disease. Early identification and intervention are essential to prevent irreversible nerve damage and optimise long-term functional outcomes. Prompt recognition of characteristic findings not only enables appropriate treatment but may also significantly improve patient prognosis.
Efficacy of radiotherapy and role of adjunctive immunochemotherapy in POEMS syndrome with solitary plasmacytoma.
Radiotherapy is a definitive treatment for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome with solitary plasmacytoma. However, data on its efficacy and the role of immunochemotherapy are limited. This study evaluated the treatment outcomes of patients with POEMS syndrome receiving radiotherapy as their primary therapy and compared the results of those treated with adjunctive immunochemotherapy with those without. A retrospective analysis of patients with POEMS syndrome referred to the University College London Hospital from 1998 to 2023 was conducted. Among 150 patients with POEMS syndrome, 30 (20%) presented with solitary plasmacytoma. Sixteen patients (53%) received radiotherapy alone, whereas 14 (47%) had combined treatment with radiotherapy and immunochemotherapy, predominantly lenalidomide, and dexamethasone. Treatment responses were greater in the combined treatment group, with clinical, vascular endothelial growth factor, hematological, and radiological responses of 100%, 92%, 100%, and 100%, respectively, compared with 87%, 92%, 85%, and 79% in patients receiving radiotherapy only. The median follow-up for the entire cohort was 124 months, with a 5-year overall survival rate of 100% and a progression-free survival (PFS) rate of 82%. For those receiving radiotherapy alone, the median follow-up was 124 months, with a 3-year PFS rate of 69%. In contrast, no progression was observed among patients treated with combined therapy during the follow-up period (range, 7-54 months). Six patients experienced disease progression, with all having received radiotherapy alone as their first-line treatment. This study demonstrated the high efficacy of radiotherapy in patients with POEMS syndrome and solitary plasmacytoma and highlighted the potential benefits of combining radiotherapy with immunochemotherapy.
Castleman Disease Variant POEMS Syndrome Presenting as Polyradiculoneuropathy in a Child: A Case Report.
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes) is a rare multisystemic disorder linked to plasma cell abnormalities, typically affecting adults. Pediatric cases are extraordinarily rare, with the youngest previously reported patient being 10 years old. We present the case of a 6-year-old boy whose symptoms included progressive lower limb weakness, lymphadenopathy, and thrombocytosis. Initially misdiagnosed as Guillain-Barré syndrome, the finding of lymphadenopathy revealing Castleman disease along with hyperpigmentation, hypertrichosis, papilledema, and hepatomegaly confirmed the diagnosis. Despite the absence of monoclonal protein and sclerotic bone lesions, the multidisciplinary approach led to successful treatment with corticosteroids, thalidomide, and cyclophosphamide, resulting in full remission. This case highlights the diagnostic challenges of POEMS syndrome in children, given its heterogeneity and overlap with other conditions. Early recognition is crucial, as pediatric patients show favorable prognosis with prompt and appropriate treatment.
AESOP syndrome: a rare and early indicator of POEMS syndrome.
Adenopathy and an extensive skin patch overlying a plasmacytoma (AESOP) syndrome is a rare condition characterised by an erythemato-violaceous patch on the skin, accompanied by an underlying solitary plasmacytoma. It may give an early clue for the diagnosis of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes (POEMS) syndrome, an uncommon multisystem disorder driven by plasma cell dyscrasia. We describe a 62-year-old man with sensorimotor peripheral neuropathy, unintentional weight loss and a persistent skin rash. Diagnostic findings, including elevated vascular endothelial growth factor, an immunoglobulin A kappa paraprotein and a skin/sternal biopsy, led to the diagnosis of AESOP and POEMS syndrome. This case underscores the importance of early recognition of AESOP syndrome as a potential lifesaving clue for the early diagnosis of POEMS syndrome.
Pachymeningeal thickening and subdural effusion in POEMS syndrome.
Publicações recentes
Morphological characteristics of the renal lesion in TAFRO syndrome and POEMS syndrome: a retrospective and multicenter study.
🥉 Relato de casoPOEMS syndrome presenting as Porto-sinusoidal vascular disease: A case report.
🥉 Relato de casoClinical impact and prognostic implications of concurrent amyloid deposition in patients with POEMS syndrome: A single-center retrospective study.
A rare case of POEMS syndrome with unique endoscopic presentation.
Prognostic value of the neutrophil-to-lymphocyte ratio in POEMS syndrome.
📚 EuropePMC1.091 artigos no totalmostrando 192
Front-line systemic treatment outcomes in POEMS syndrome.
British journal of haematologyWhen Foot Drop Tells a Bigger Story: POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Plasma Cell Disorder, and Skin Changes) Syndrome Revealed by Femoral Plasmacytoma.
CureusAtypical Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes (POEMS) Syndrome.
CureusA woman with fever, feet hypostesia and disseminated papules.
European journal of internal medicineMonoclonal gammopathies of cutaneous significance: A nomenclature and pathophysiology-based classification.
Journal of the American Academy of DermatologyImmunophenotypic characteristics of plasma cells in POEMS syndrome.
Cytometry. Part B, Clinical cytometryPOEMS syndrome with cardiovascular lesions as the initial manifestation: a case report and literature review.
Frontiers in cardiovascular medicineLong-term outcomes of newly diagnosed POEMS syndrome patients treated with bortezomib-based therapies.
CancerPOEMS syndrome: a neuromuscular perspective.
Journal of neurology, neurosurgery, and psychiatryPachymeningeal Involvement in POEMS Syndrome: Longitudinal Follow-Up Study and Correlation With Therapeutic Response.
Journal of the peripheral nervous system : JPNSEfficacy of radiotherapy and role of adjunctive immunochemotherapy in POEMS syndrome with solitary plasmacytoma.
Blood advancesCase Report: POEMS syndrome secondary to multiple solitary plasmacytomas complicated by hypertriglyceridemia.
Frontiers in medicineIvory Vertebra: A Rare Skeletal Manifestation of POEMS Syndrome.
QJM : monthly journal of the Association of PhysiciansNeurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center.
Muscle & nerveRefractory ascites: unveiling POEMS syndrome as the underlying cause: a case report and literature review.
Frontiers in medicine[POEMS syndrome misdiagnosed as systemic sclerosis: A case report].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciencesEffective front-line treatment of osteosclerotic myeloma with POEMS syndrome with daratumumab, lenalidomide and dexamethasone: a case report and literature review.
Acta clinica BelgicaBeyond the Obstruction: Recognising Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Plasma Cell Disorder, and Skin Changes (POEMS) Syndrome in a Patient With Budd-Chiari Syndrome.
CureusPOEMS syndrome: diagnosis, treatments, and outcomes.
Hematology. American Society of Hematology. Education ProgramCharacteristics of rare diseases cases: A summary analysis of hospitalized patients at a hospital in Western China from 2015 to 2023.
Intractable & rare diseases researchCase Report: Secondary myelodysplastic syndrome following autologous stem cell transplantation in a patient with POEMS syndrome.
Frontiers in immunologyMultidisciplinary Intensive Care Management of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes (POEMS) Syndrome: A Case Report.
CureusSecondary Neuropathy From Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Case Report.
CureusPOEMS syndrome complicated by portal hypertension resembling decompensated cirrhosis: a case report and diagnostic insights.
Frontiers in medicine[POEMS syndrome: A complex diagnostic case under the guise of chronic polyneuropathy].
Zhurnal nevrologii i psikhiatrii imeni S.S. KorsakovaIgA λ-Type Schnitzler Syndrome With Edema and Numbness.
The Journal of dermatologyLenalidomide-associated pure red cell aplasia during the treatment of POEMS syndrome: A case report and brief review of the literature.
Medicine internationalAI-driven proteomics: unlocking early cardiac detection in POEMS syndrome.
Annals of medicine and surgery (2012)Early diagnosis of POEMS syndrome prompted by skin findings and bone window computed tomography.
Kidney international[IgM- κ and IgM- λ biclonal POEMS syndrome combined with essential thrombocythemia: a case report].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhiHemangioma as a Primary Manifestation of POEMS Syndrome.
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood TransfusionPerformance of Large Language Models in Diagnosing Rare Hematologic Diseases and the Impact of Their Diagnostic Outputs on Physicians: Combined Retrospective and Prospective Study.
Journal of medical Internet researchPOEMS Syndrome Without a Detectable Monoclonal Peak: The Critical Role of VEGF and Bone Marrow Biopsy in Diagnosis.
Case reports in hematologyCastleman Disease Variant POEMS Syndrome Presenting as Polyradiculoneuropathy in a Child: A Case Report.
Journal of child neurologyDescription of TEMPI syndrome in Waldenström's macroglobulinemia.
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnostiTargeting CD38 with Daratumumab in a Newly Diagnosed Case of POEMS Syndrome with a 17p Deletion in a Solitary Plasmacytoma of the Bone: A Case Study and Literature Review.
Neurology IndiaPOEMS Syndrome Masquerading as Metastatic Prostate Cancer Based on PSMA Avid Lesions.
Case reports in hematologyConcurrent AESOP and POEM syndrome presenting as an indurated plaque: AESOP's paraneoplastic POEM.
JAAD case reportsPOEMS syndrome: Two cases for the general physician.
Clinical medicine (London, England)AESOP syndrome: a rare and early indicator of POEMS syndrome.
Practical neurologyPOEMS syndrome presenting with Vibrio vulnificus-like cutaneous lesions: a CARE guidelines-compliant case report.
Frontiers in medicineThe morphological spectrum of Castleman disease and related disorders: a report from the Lymphoma Workshop of the 22nd Meeting of the European Association of Hematopathology.
Virchows Archiv : an international journal of pathologyInterleukin-6 is a highly prognostic biomarker for POEMS syndrome.
LeukemiaUnicentric Castleman disease following POEMS syndrome remission.
Journal of hematopathologyDelayed Diagnosis of Poems Syndrome, How AI Tools Can Enhance Diagnostic Accuracy.
European journal of case reports in internal medicine[Chinese expert consensus on the diagnosis and treatment of POEMS syndrome (2025)].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhiVasculitic Neuropathy With Iron Deficiency-Related Chronic Inflammation Followed by Elevated Serum Vascular Endothelial Growth Factor: A POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome Mimic.
CureusCorrigendum to "First-line therapy with daratumumab, lenalidomide and dexamethasone for patient with POEMS syndrome: A case report" [Leukemia Research Reports (2024) Volume 22, 100491].
Leukemia research reportsA scoping review: POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder and Skin Changes), physical recovery, and rehabilitation.
Clinical rehabilitationTeclistamab for heavily pretreated relapsed / refractory POEMS syndrome.
HaematologicaEssential thrombocythemia as an initial presentation of polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome with complete response to the bortezomib, cyclophosphamide, dexamethasone regimen: a case report.
Journal of medical case reportsA case report of Castleman disease variant of POEMS syndrome presenting with prominent polyserositis and renal impairment.
Frontiers in medicinePachymeningeal thickening and subdural effusion in POEMS syndrome.
Practical neurologyUpdate on paraproteinemic neuropathy.
Current neurology and neuroscience reportsSuccessful treatment with carfilzomib and dexamethasone for relapsed/refractory POEMS syndrome: a case report and review of literature.
Frontiers in oncology[A case of POEMS syndrome presenting craniocervical vascular stenosis].
Rinsho shinkeigaku = Clinical neurologyDaratumumab (anti-CD38)- and elotuzumab (anti-SLAMF7)-based treatments for refractory POEMS syndrome: a single-center case series.
Hematology (Amsterdam, Netherlands)Lecture 4. Clonal Plasma Cell Precursors.
Hematological oncologyGrowth Differentiation Factor-15 as a Potential Biomarker for Renal Involvement in POEMS Syndrome.
International journal of nephrology and renovascular diseaseIgA nephropathy, non-cirrhotic portal fibrosis, and POEMS syndrome: A rare combination in the long-term follow-up of Sjögren's syndrome.
The Journal of international medical researchUnmasking POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome in a Heart Failure Patient: A Diagnostic Challenge.
CureusSuccessful assisted pregnancy outcome in a patient with POEMS syndrome.
BMJ case reportsPlasma cell myeloma with an evolving diagnostic complexity: A case report.
Oncology lettersClonal Hematopoietic Mutations in Plasma Cell Disorders: Clinical Subgroups and Shared Pathogenesis.
Genomics, proteomics & bioinformaticsDiagnostic Challenges of Polyneuropathy, Organomegaly, Endocrinopathy, M-protein, and Skin Changes (POEMS) Syndrome: A Rare Case Report and Review of the Literature.
Cardiovascular & hematological disorders drug targetsIdiopathic Nodular Glomerulosclerosis in a Long-term Passive Smoker With Recently Diagnosed Hypertension: A Case Report.
Journal of investigative medicine high impact case reportsVEGF as a Relapse Marker and an Intensity of Disease Marker in Patients Affected by POEMS Syndrome Treated With Autologous Peripheral Blood Stem Cell Transplantation.
Hematological oncologyPrevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy.
European journal of neurologyClinical and biochemical characteristics for patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome: a pilot observational study.
Frontiers in neurologyDaratumumab desensitization: Novel approaches in POEMS syndrome experience.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy PractitionersAssociation of co-existing vitamin B6 and B12 deficiency with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes (POEMS) syndrome: a case report.
BMC neurologyPOEMS Syndrome Presenting as First-Time Heart Failure Exacerbation.
JACC. Case reportsUnraveling Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes Syndrome: Diagnostic Challenges and Therapeutic Strategies at a National Tertiary Care Center.
CureusClinical Impact of Osteolytic Bone Lesions in POEMS Syndrome: A Single-Center Experience of 114 Patients.
Hematological oncologyUtility of word embeddings from large language models in medical diagnosis.
Journal of the American Medical Informatics Association : JAMIACase report: Atypical POEMS syndrome without polyneuropathy, complicated by borderline TAFRO syndrome.
Frontiers in medicineA case report of an M protein-negative patient with POEMS syndrome associated with renal involvement.
BMC nephrologyCastleman disease variant of POEMS syndrome without M protein: a case report.
Frontiers in oncologyFirst-line therapy with daratumumab, lenalidomide and dexamethasone for patient with POEMS syndrome: A case report.
Leukemia research reportsCapillary leak phenotype as a major cause of death in patients with POEMS syndrome.
LeukemiaCastleman disease-type histopathological patterns of lymph nodes in patients with plasma cell neoplasia and POEMS syndrome.
Annals of diagnostic pathologyPOEMS syndrome complicated with acute cerebral infarction: A case report and literature review.
Asian journal of surgeryPolyneuropathy With Motor Conduction Block in POEMS.
Muscle & nerveOsteosclerosing multiple myeloma: A case highlighting critical value of image findings for the diagnosis.
Radiology case reports[POEMS syndrome. Report of three cases and literature review].
Revista medica del Instituto Mexicano del Seguro Social[POEMS syndrome mimicking CIDP].
Der NervenarztDisease Characteristics and Outcomes of 493 Young Myeloma Patients Treated With Modern Therapies: A Canadian Myeloma Research Group Database Study.
Cancer medicine[POEMS Syndrome: Report of Two Cases].
Revista medica de ChileTop 10 Clinical Pearls in Paraproteinemic Neuropathies.
Seminars in neurologyCastleman Disease: A Rare Lymphoproliferative Disorder With Diverse Clinical Presentation, Diagnosis, and Treatment Approach.
CureusEfficacy of nebulized GM-CSF inhalation in preventing oral mucositis in patients undergoing hematopoietic stem cell transplantation: A retrospective study.
HeliyonAcute leukoencephalopathy associated with daratumumab treatment in POEMS syndrome: a case report.
Frontiers in immunology[Diagnosis and management of POEMS syndrome].
[Rinsho ketsueki] The Japanese journal of clinical hematologyA case of paraprotein-negative POEMS syndrome: Case report and literature review.
Medicine[Clinical characteristics of POEMS syndrome initially diagnosed as increased extravascular volume load: a single-center retrospective study].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhiIntersecting Pathologies: A Case Report on the Co-presentation of Quasi-Moyamoya Disease and Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Plasma Cell Disorder, and Skin Changes (POEMS) Syndrome.
CureusAtypical POEMS syndrome: Report of a patient.
Medicina clinicaDramatically elevated plasma vascular endothelial growth factor levels from influenza A infection in polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome: A case report.
EJHaemCase report: DKRd regimen in the treatment of newly diagnosed POEMS syndrome and literature review.
Frontiers in oncologyThe Latin-American Experience in POEMS Syndrome: A Study of the GELAMM (Grupo de Estudio Latinoamericano de Mieloma Múltiple).
Acta haematologicaCase report: POEMS syndrome with portal hypertension.
Frontiers in medicineRequirement of Repeated Serum VEGF Measurements in POEMS Syndrome.
Internal medicine (Tokyo, Japan)Plasma cell and neutrophil enriched neovascularization with granulomatous lymphangitis in POEMS syndrome.
JAAD case reportsIxazomib in POEMS syndrome: 'Ixa'ctly what we need?
British journal of haematologyMonoclonal gammopathy of clinical signifi cance with osteosclerotic lesions - a case report and a literature review.
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnostiAn open-label, prospective trial to evaluate the efficacy and safety of ixazomib in combination with cyclophosphamide and dexamethasone in patients with newly diagnosed POEMS syndrome.
British journal of haematology[The Preventive Effect of Levofloxacin Combined with G-CSF or Only G-CSF Supportive Therapy on Infection in Autologous Hematopoietic Stem Cell Transplantation].
Zhongguo shi yan xue ye xue za zhiUnusual Types of Plasma Cell Dyscrasias Associated With HIV: Polyneuropathy, Organomegaly, Endocrinopathy, M-protein, and Skin Changes (POEMS) Syndrome.
CureusLong-term outcomes of newly diagnosed POEMS syndrome patients who received first-line lenalidomide-based therapy.
HaematologicaRecent insights into haematology and peripheral nerve disease.
Current opinion in neurologyPOEMS syndrome with undetectable M-protein: a case report and literature review.
Diagnostic pathology[A race against time: POEMS syndrome].
Ideggyogyaszati szemleParaproteinemic neuropathies.
Muscle & nerveTAFRO Syndrome on 18F-FDG-PET/CT: An Appealing Diagnostic Tool.
Diagnostics (Basel, Switzerland)Elevated serum levels of soluble B-cell maturation antigen as a prognostic biomarker for multiple myeloma.
Clinical and experimental immunologyDetection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry.
Scientific reportsPOEMS syndrome associated with IgM lambda paraprotein. A case report and review of the literature.
Journal of the neurological sciencesWhole-body magnetic resonance neurography in patients with chronic inflammatory demyelinating polyneuropathy.
Muscle & nerveHydrocephalus associated with POEMS syndrome.
Medicina clinicaPOEMS syndrome-An unusual cause for high-gradient ascites.
Indian journal of gastroenterology : official journal of the Indian Society of GastroenterologyA Case Report of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Diagnostic Iceberg.
CureusThe challenge of detecting monoclonal protein in POEMS syndrome: two case reports.
Hong Kong medical journal = Xianggang yi xue za zhiGammopathic dermopathy: characterization of cutaneous MGUS.
Leukemia & lymphomaNon-POEMS osteosclerotic multiple myeloma: Clinical characteristics and differential diagnosis.
Journal of bone oncologyHematologic malignancies and hematopoietic stem cell transplantation.
Handbook of clinical neurologyAdenopathy and Extensive Skin patch Overlaying a Plasmacytoma and other proliferation (AESOP) syndrome associated with Hodgkin lymphoma.
Annales de dermatologie et de venereologieLow serum total cholesterol levels predict inferior prognosis of patients with POEMS syndrome.
Discover oncologyIntramedullary leukocytoclastic vasculitis and neutrophil extracellular trap (NET) formation in POEMS syndrome.
Annals of hematologyCalciphylaxis in POEMS syndrome: Case report.
Rare (Amsterdam, Netherlands)A case of POEMS syndrome comprising of a complicated diagnostic procedure: Case report.
MedicineChronic Inflammatory Demyelinating Polyradiculoneuropathy as a Presentation of Plasmacytoma.
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaCase report: POEMS syndrome masquerades as diabetic foot.
Frontiers in neurologyPolyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome with dilated cardiomyopathy: A case report.
World journal of clinical casesEfficacy of bortezomib, cyclophosphamide, and dexamethasone for newly diagnosed POEMS syndrome patients.
Therapeutic advances in neurological disordersFrom hepatomegaly to POEMS syndrome: A case report.
Hepatology forumA Multicenter Analysis of Clinical Features and Long-Term Outcomes of POEMS Syndrome in Korea.
Journal of Korean medical scienceClinico-pathological profile of patients with plasma cell neoplasms with special reference to bone marrow fibrosis and amyloid deposition.
Journal of clinical and experimental hematopathology : JCEHPOEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Plasma Cell Disorder, and Skin Changes) Syndrome as a Sequela of Castleman Disease: A Case Report.
CureusPOEMS syndrome characterized by bone lesions: A case report.
MedicineSpecific dermoscopic findings in glomeruloid haemangioma for diagnosis of POEMS syndrome.
Journal of the European Academy of Dermatology and Venereology : JEADVPulmonary manifestations of POEM syndrome: a retrospective analysis of 282 cases.
BMC pulmonary medicineUnraveling the Neurological Complexity of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes Syndrome: A Report of a Challenging Case of a Young Woman and Cutting-Edge Advancements in the Field.
Diseases (Basel, Switzerland)Concomitant AESOP and POEMS Syndrome in the Context of Osseous and Cutaneous Plasmacytomas: Answer.
The American Journal of dermatopathologyLong-Term Outcomes of Autologous Stem Cell Transplantation in Patients with Newly Diagnosed POEMS Syndrome.
Transplantation and cellular therapyGiant papillary hemangioma-A rare tumor with an exceptional size.
Journal of cutaneous pathologyPOEMS syndrome in the 21st century: A bibliometric analysis.
HeliyonSmall vessel platelet thrombosis in the peripheral nerves in POEMS syndrome.
Muscle & nerveA case report on POEMS syndrome with high parathyroid hormone and repeated surgery, a rare presentation of a rare disease.
International journal of surgery case reportsCastleman Disease Variant of Poems Syndrome Complicated with Multiple Osteosclerotic Lesions.
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood TransfusionBaricitinib treatment for refractory skin changes in POEMS syndrome: a case report.
Frontiers in pharmacologyAdenopathy and extensive skin patch overlying a plasmacytoma (AESOP) syndrome: a case report and literature review.
Annals of hematologyPOEMS syndrome: Update on diagnosis, risk-stratification, and management.
American journal of hematologyA Rare Cause of Chronic Diarrhea and Peripheral Neuropathy.
GastroenterologyRegular assessment of serum vascular endothelial growth factor levels to monitor POEMS syndrome.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyPOEMS syndrome: an unusual cause of exuberant callus formation.
BMJ case reportsWhat is the best treatment strategy before autologous peripheral blood stem cell transplantation in POEMS syndrome?
HaematologicaCharacteristics and outcome of infectious complications after autologous hematopoietic cell transplantation in multiple myeloma patients.
Transplant infectious disease : an official journal of the Transplantation SocietyDaratumumab monotherapy for relapsed POEMS syndrome.
American journal of hematology[Identification of transcriptional features and surface markers of plasma cell clones in POEMS syndrome by single-cell RNA sequencing].
[Rinsho ketsueki] The Japanese journal of clinical hematologyPOEMS syndrome: A rare entity.
Indian journal of pathology & microbiologyTreatment-responsive glycogen storage myopathy in a patient with POEMS syndrome: A new monoclonal gammopathy-associated myopathy.
European journal of neurologyTreatment and outcome of second-line therapy for POEMS syndrome after autologous stem cell transplantation.
Bone marrow transplantationAlterations in choroidal vascular structures due to serum levels of vascular endothelial growth factor in patients with POEMS syndrome.
Scientific reportsUltrasound-based radiomic analysis of the peripheral nerves for differentiation between CIDP and POEMS syndrome.
Acta radiologica (Stockholm, Sweden : 1987)A case report of POEMS syndrome with lower limb numbness and weakness.
Asian journal of surgeryDaratumumab, carfilzomib, and pomalidomide for the treatment of POEMS syndrome: The Mayo Clinic Experience.
Blood cancer journalPOEMS Syndrome-Clinical Picture and Management. Current Knowledge.
Clinical lymphoma, myeloma & leukemiaDutcher bodies as a diagnostic key to POEMS syndrome.
EJHaemT-Cells Subsets in Castleman Disease: Analysis of 28 Cases Including Unicentric, Multicentric and HHV8-Related Clinical Forms.
International journal of molecular sciencesPorto-sinusoidal vascular disorder, report of a novel association with POEMS syndrome. Future challenge for the hepatologist.
Clinics and research in hepatology and gastroenterologyEpidemiology of monoclonal gammopathy in Morocco - A hospital-based study.
Cancer reports (Hoboken, N.J.)Surgical revascularization for quasi-moyamoya disease associated with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome: a case report and literature review.
Nagoya journal of medical sciencePOEMS syndrome: origination from clonal plasma cells or B cells?
Hematology (Amsterdam, Netherlands)[POEMS syndrome in the elderly. Clinical case and review of the literature].
Revista espanola de geriatria y gerontologiaSuccessful treatment with bortezomib for POEMS syndrome, overcoming complicated severe heart block.
Clinical case reports[POEMS Syndrome with Peripheral Edema and Ascites as the Main Manifestations:Report of One Case].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae SinicaeBiclonal lymphoplasmacytic lymphoma/Waldenström macroglobulinemia associated with POEMS syndrome: A case report and literature review.
Oncology lettersPOEMS Syndrome - A Diagnostic Dilemma with Challenging Presentation.
Journal of community hospital internal medicine perspectivesOcular complications of plasma cell dyscrasias.
European journal of ophthalmologyThe exploration of B cell maturation antigen expression in plasma cell dyscrasias beyond multiple myeloma.
BMC cancerCoexistence of primary mediastinal MALT lymphoma and multiple myeloma like POEMS syndrome: A case report and literature review.
MedicinePolyneuropathy organomegaly endocrinopathy M-protein and skin changes syndrome with ascites as an early-stage manifestation: A case report.
World journal of clinical casesSolitary hyoid plasmacytoma with unicentric Castleman disease: A case report and review of literature.
World journal of clinical casesPOEMS syndrome presents with a distended abdomen: A case report.
The Journal of international medical researchIxazomib Combined With Autologous Stem Cell Transplantation for POEMS Syndrome: A Case Report and Meta-Analysis.
Technology in cancer research & treatmentBetter prognosis in POEMS patients with cerebral infarction before polyneuropathy.
HeliyonA rare case of POEMS syndrome presenting as essential thrombocythemia.
Oxford medical case reportsPOEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome Masquerading as Chronic Inflammatory Polyradiculoneuropathy: A Case Report.
CureusRecent Advances in the Treatment and Supportive Care of POEMS Syndrome.
Journal of clinical medicineA POEMS syndrome patient with idiopathic non-cirrhotic portal hypertension received the transjugular intrahepatic portosystemic shunt: a case report and literature review.
Nigerian journal of clinical practicePOEMS syndrome: A rare cause of ascites and pelvic effusion.
Clinical case reportsMutations in the plasma cell clone identify mechanism of polyneuropathy in a case of POEMS syndrome associated with Castleman disease and multiple myeloma.
Annals of hematologyAssociações
Organizações que acompanham esta doença — pra ter apoio e orientação
Ainda não temos associações cadastradas para Síndrome POEMS.
É de uma associação que acompanha esta doença? Fale com a gente →
Comunidades
Grupos ativos de quem convive com esta doença aqui no Raras
Ainda não existe comunidade no Raras para Síndrome POEMS
Pacientes, familiares e cuidadores se organizam em comunidades pra compartilhar experiências, fazer perguntas e se apoiar. Você pode ser o primeiro.
Tire suas dúvidas
Perguntas, dicas e experiências compartilhadas aqui na página
Participe da discussão
Faça login para postar dúvidas, compartilhar experiências e interagir com especialistas.
Fazer loginDoenças relacionadas
Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico
Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- POEMS syndrome: a neuromuscular perspective.
- Efficacy of radiotherapy and role of adjunctive immunochemotherapy in POEMS syndrome with solitary plasmacytoma.
- Castleman Disease Variant POEMS Syndrome Presenting as Polyradiculoneuropathy in a Child: A Case Report.
- AESOP syndrome: a rare and early indicator of POEMS syndrome.
- Pachymeningeal thickening and subdural effusion in POEMS syndrome.
- Morphological characteristics of the renal lesion in TAFRO syndrome and POEMS syndrome: a retrospective and multicenter study.
- POEMS syndrome presenting as Porto-sinusoidal vascular disease: A case report.
- Clinical impact and prognostic implications of concurrent amyloid deposition in patients with POEMS syndrome: A single-center retrospective study.
- A rare case of POEMS syndrome with unique endoscopic presentation.
- Prognostic value of the neutrophil-to-lymphocyte ratio in POEMS syndrome.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:2905(Orphanet)
- MONDO:0017364(MONDO)
- GARD:7411(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q2553422(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
