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Síndrome pós-poliomielite
ORPHA:2942CID-10 · G14CID-11 · 8B62DOENÇA RARA

A síndrome pós-poliomielite (SPP) é um distúrbio neurológico caracterizado pelo desenvolvimento de novos sintomas neuromusculares, como fraqueza muscular progressiva ou fadiga muscular anormal, que ocorre em sobreviventes da forma paralítica aguda da poliomielite, 15-40 anos após a recuperação da doença, e que é inexplicável por outras causas médicas. Outras manifestações que podem ocorrer gradualmente incluem fadiga generalizada, atrofia muscular, dores musculares e articulares, intolerância ao frio e dificuldades em dormir, engolir ou respirar.

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Introdução

O que você precisa saber de cara

📋

A síndrome pós-poliomielite (SPP) é um distúrbio neurológico caracterizado pelo desenvolvimento de novos sintomas neuromusculares, como fraqueza muscular progressiva ou fadiga muscular anormal, que ocorre em sobreviventes da forma paralítica aguda da poliomielite, 15-40 anos após a recuperação da doença, e que é inexplicável por outras causas médicas. Outras manifestações que podem ocorrer gradualmente incluem fadiga generalizada, atrofia muscular, dores musculares e articulares, intolerância ao frio e dificuldades em dormir, engolir ou respirar.

Pesquisas ativas
2 ensaios
29 total registrados no ClinicalTrials.gov
Publicações científicas
82 artigos
Último publicado: 2025 May 5

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
Adolescent
+ adult, elderly
🏥
SUS: Cobertura mínimaScore: 15%
CID-10: G14
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (2)
0202010694
Sequenciamento completo do exoma (WES)genetic_test
0301070040
Atendimento em reabilitação — doenças rarasrehabilitation
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

💪
Músculos
4 sintomas
🧠
Neurológico
2 sintomas
🦴
Ossos e articulações
2 sintomas
🫁
Pulmão
2 sintomas
🫃
Digestivo
1 sintomas

+ 8 sintomas em outras categorias

Características mais comuns

90%prev.
Fraqueza muscular
Muito frequente (99-80%)
90%prev.
Dor
Muito frequente (99-80%)
55%prev.
Fadiga
Frequente (79-30%)
55%prev.
Artralgia
Frequente (79-30%)
55%prev.
Hipersonia
55%prev.
Dificuldade para subir escadas
Frequente (79-30%)
19sintomas
Muito frequente (2)
Frequente (7)
Ocasional (8)
Muito raro (1)
Sem dados (1)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 19 características clínicas mais associadas, ordenadas por frequência.

Fraqueza muscularMuscle weakness
Muito frequente (99-80%)90%
DorPain
Muito frequente (99-80%)90%
FadigaFatigue
Frequente (79-30%)55%
ArtralgiaArthralgia
Frequente (79-30%)55%
HipersoniaHypersomnia
Frequente55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2025
Total histórico82PubMed
Últimos 10 anos166publicações
Pico201527 papers
Linha do tempo
2025Hoje · 2026🧪 1982Primeiro ensaio clínico📈 2015Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
3Fase 32
·Pré-clínico8
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 10 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Síndrome pós-poliomielite

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

1 pesquisa recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

29 ensaios clínicos encontrados, 2 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
26 papers (10 anos)
#1

Digital twin frameworks for polio and post-polio neurodegeneration: Toward predictive, personalised lifelong neuro-rehabilitation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026 Jan 08

Poliomyelitis is a neuroinvasive viral disease that, despite near-global eradication, has left millions of survivors worldwide with lifelong motor-system injury. Many develop delayed neurological decline decades later in the form of Post-polio syndrome, characterised by progressive weakness, fatigue, pain, and respiratory compromise. Disease trajectories are highly heterogeneous, unpredictable, and shaped by complex interactions between residual motor-neuron pools, muscle adaptation, ageing, metabolism, and immune tone. Conventional care relies on episodic clinical review and reactive rehabilitation, with limited capacity for long-term personalised forecasting. Digital-twin technology, defined as an adaptive computational model that continuously mirrors an individual's biological and functional state, offers a transformative framework for predictive and precision-guided lifelong polio care. By integrating neuromuscular physiology, biomechanics, metabolic status, wearable sensor data, and rehabilitation responses, digital twins could enable real-time modelling of motor-unit decline, functional reserve, respiratory vulnerability, and fatigue dynamics. This article outlines a focused conceptual framework for polio digital twins, emphasising model architecture, feedback loops, and translational applications, rather than virological biology. The proposed framework positions digital twins as a missing precision-medicine layer for a neglected global survivor population.

#2

Determining the presence of restless legs syndrome in patients with poliomyelitis sequelae and its effect on pain, fatigue, sleep and quality of life.

Sleep &amp; breathing = Schlaf &amp; Atmung2026 Feb 18

Investigation of Restless Legs Syndrome (RLS) in patients with poliomyelitis sequelae (PS) and the effect of RLS on pain, fatigue, sleep and quality of life (QoL). We investigated the presence of RLS in patients with PS who consecutively applied to the neurology outpatient clinic and did not have secondary causes of RLS. Gender, age, side affected by PS, leg muscle strength and length, International RLS Study Group criteria, Pittsburgh Sleep Quality Index questionnaire, Fatigue Severity Scale, SF-36 Form scores were recorded. After receiving a diagnosis of RLS, patients completed the RLS Severity Rating Scale (RLS-SWS) questionnaire. We identified RLS in 12 (37.5%) of the 32 patients included in the study. There were no differences in demographic characteristics. The leg lengths in the patients with RLS (PwRLS) were significantly shorter (p < 0.001). PwRLS had shorter sleep duration, longer latency, and worse sleep quality and fatigue severity scores (p < 0.001). The pain score was found to be statistically significantly higher in the PwRLS group (p = 0.007). There were no differences in other QoL areas. In the PwRLS study, the RLS-SWS score was positively correlated with sleep latency, sleep quality, and pain and fatigue scores. It was also negatively correlated with sleep duration (p < 0.001). These findings demonstrate that RLS, which has an effective treatment, is a prevalent condition among PS patients that worsens sleep quality and increases pain. Clinicians should screen PS patients who complain of leg pain and/or sleep disturbances for RLS and provide appropriate treatment.

#3

[Late-onset sequel states of poliomyelitis (postpolyomelitic syndrome)].

Revista espanola de salud publica2026 Feb 12

Poliomyelitis remains a Public Health challenge in countries with low vaccination coverage and outbreaks of vaccine-derived polioviruses. The aim of this paper was to review the current evidence on post-polio syndrome (PPS), including its pathophysiological basis, clinical manifestations, diagnostic criteria, and current therapeutic approaches. A narrative review of PubMed, Scopus, Web of Science, and World Health Organization documents was conducted, prioritizing systematic reviews, cohort studies, and clinical trials published between 1980 and 2024. PPS affects 20-50% of polio survivors. It is characterized by progressive muscle weakness, fatigue, and pain decades after the initial infection. Its etiology remains unclear; proposed mechanisms include degeneration of reinnervated motor units, neuromuscular dysfunction, viral persistence, and autoimmunity. No pathogenetic treatments are available; management is symptomatic and multidisciplinary. PPS is a chronic condition with high prevalence among poliomyelitis survivors. Current treatment focuses on rehabilitation, respiratory care, fatigue management, and psychological support. Further research is required to develop specific therapies. La poliomielitis sigue siendo un desafío de Salud Pública en países con bajas coberturas vacunales y con brotes de poliovirus derivados de la vacuna. El objetivo de este artículo de revisión fue revisar la evidencia disponible sobre el síndrome postpoliomielítico (SPP), sus bases fisiopatológicas, manifestaciones clínicas, criterios diagnósticos y abordajes terapéuticos actuales. Se realizó una revisión bibliográfica narrativa de artículos publicados en PubMed, Scopus, Web of Science y documentos de la Organización Mundial de la Salud, priorizando revisiones sistemáticas, estudios de cohortes y ensayos clínicos entre 1980 y 2024. El SPP afecta a entre el 20%-50% de los supervivientes de polio. Se caracteriza por debilidad muscular progresiva, fatiga y dolor, tras décadas de estabilidad clínica. Su etiología es desconocida; las teorías incluyen degeneración de unidades motoras reinervadas, disfunción neuromuscular, persistencia viral y autoinmunidad. No existen terapias específicas; el manejo es sintomático y multidisciplinar. El SPP constituye una entidad crónica de alta prevalencia en sobrevivientes de la poliomelitis. El tratamiento actual se centra en rehabilitación, cuidados respiratorios, manejo de la fatiga y apoyo psicológico. Se requieren más investigaciones para desarrollar terapias específicas.

#4

Metabolic Syndrome in Ambulatory People With Post-Polio Syndrome, Charcot-Marie-Tooth Disease, and Other Neuromuscular Diseases.

American journal of physical medicine &amp; rehabilitation2026 Jan 01

The metabolic syndrome is a growing health issue. This study evaluated the prevalence of metabolic syndrome and individual metabolic syndrome risk factors, in people with different neuromuscular diseases. We used baseline data of a randomized controlled trial on the efficacy of a physical activity program in neuromuscular diseases. Metabolic syndrome was defined as the presence of at least three out of five risk factors of the revised National Cholesterol Education Program Adult Treatment Panel III. The 84 participants (50 female, median age = 63 yrs, interquartile range = 48, 68 yrs) were diagnosed with post-polio syndrome ( n = 22), Charcot-Marie-Tooth disease ( n = 37) or other neuromuscular diseases ( n = 25). Metabolic syndrome was present in 18 participants (21%). The most common risk factors were hypertension (56%), central obesity (49%), and increased fasting blood glucose (33%). Logistic regression results showed that adjusted for age and muscle strength as confounders, participants with Charcot-Marie-Tooth disease (Exp(B) = 0.107, 95% confidence interval: 0.019-0.609) and other neuromuscular diseases (Exp(B) = 0.039, 95% confidence interval: 0.004-0.390) had significantly lower odds of metabolic syndrome compared with post-polio syndrome. The metabolic syndrome prevalence that we found is comparable to the general Dutch population. However, a focus on the prevention of metabolic syndrome in neuromuscular rehabilitation is warranted, as certain neuromuscular diseases subgroups may be at increased risk of developing metabolic syndrome.

#5

Low-grade persistent poliovirus infection in long-term polio survivors diagnosed with post-polio syndrome: diagnostic and clinical implications.

Journal of neurology2025 Sep 06

Despite extensive research, the pathogenesis of Post-Polio Syndrome (PPS) remains unclear. We investigated 251 participants from Northern Italy: long-term polio survivors with PPS, long-term polio survivors with stable polio, family members of both groups, subjects with neurological disorders other than poliomyelitis, and healthy controls. This study investigated whether persistent viral activity or the existence of viral reservoirs contributes to causing PPS. Poliovirus (PV) genomes and proteins were detected in 87.2% of PPS cases versus 12.0% of stable polio cases and 3.5% of control family members, but not in pathologic and healthy controls. Among PPS patients, the highly concordant detection of PV strains in both peripheral blood leukocytes and cerebrospinal fluid (CSF) suggests the presence of an ongoing low-grade infection. Conversely, the very low detection rate in family members indicates the minimal transmissibility of these PV variants. Molecular analysis of the detected PV strains revealed mutations across most genome regions, likely leading to defects in virus replication. Furthermore, in cell cultures, PPS-derived PV strains induced the release of inflammatory mediators (IL6, IL8, MCP1) that may play a pathogenic role. These findings have several clinical implications. First, the presence of mutated PV forms in blood leukocytes and CSF could serve as a diagnostic marker for PPS. Second, the persistent virus infection suggests that antiviral treatments might help reduce PPS progression. Furthermore, advanced genome sequencing techniques hold potential for distinguishing vaccine-derived from wild-type PV strains, thereby refining our understanding of PPS and the full spectrum of polio disorders.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC33 artigos no totalmostrando 162

2025

Quality of life and associated factors in tunisian postpoliomyelitis syndrome patients.

La Tunisie medicale
2026

Determining the presence of restless legs syndrome in patients with poliomyelitis sequelae and its effect on pain, fatigue, sleep and quality of life.

Sleep &amp; breathing = Schlaf &amp; Atmung
2026

[Late-onset sequel states of poliomyelitis (postpolyomelitic syndrome)].

Revista espanola de salud publica
2026

Digital twin frameworks for polio and post-polio neurodegeneration: Toward predictive, personalised lifelong neuro-rehabilitation.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2025

[Current situation of people with polio and post-polio syndrome in Spain].

Revista espanola de salud publica
2025

Low-grade persistent poliovirus infection in long-term polio survivors diagnosed with post-polio syndrome: diagnostic and clinical implications.

Journal of neurology
2025

Plummer-Vinson syndrome in a postpolio patient: a rare intersection of neuromuscular and nutritional sequelae.

BMJ case reports
2026

Metabolic Syndrome in Ambulatory People With Post-Polio Syndrome, Charcot-Marie-Tooth Disease, and Other Neuromuscular Diseases.

American journal of physical medicine &amp; rehabilitation
2025

[Guide of recommendations for the diagnosis and neurorrehabilitative treatment of post-poliomielytic sequelar conditions].

Revista espanola de salud publica
2025

Anterolateral thigh flap harvested from paralyzed limbs in post-polio syndrome for tongue reconstruction-a case report and a review of the literature.

Chinese clinical oncology
2025

Survey of changes in subjective symptoms among Japanese polio survivors over 10 years.

Journal of rehabilitation medicine
2025

Changes in self-reported impairments over 10 years in people with late effects of polio and associated factors: A longitudinal cohort study.

Annals of physical and rehabilitation medicine
2025

Review of the anaesthetic management of patients with post-polio syndrome.

British journal of anaesthesia
2025

Post-polio hospital admissions in Australia over a 10-year period: An observational study and analysis of trends by month, location, and comparable conditions.

Journal of public health (Oxford, England)
2025

The presence of unknown polio engagement confirmed by electromyography and muscle testing.

Journal of rehabilitation medicine
2024

Total knee arthroplasty in patient with poliomyelitis sequelae: maintaining a recurvatum is associated with better mid-term functional results.

Archives of orthopaedic and trauma surgery
2024

Neurobiological modulation with REAC technology: enhancing pain, depression, anxiety, stress, and quality of life in post-polio syndrome subjects.

Scientific reports
2024

Validity of Cardiopulmonary Exercise Testing for Assessing Aerobic Capacity in Neuromuscular Diseases.

Archives of physical medicine and rehabilitation
2024

Post-polio syndrome - somatosensory dysfunction and its relation to pain: a pilot study with quantitative sensory testing.

Journal of rehabilitation medicine
2024

COVID-19 and the Postviral Syndrome of Long COVID: Where We Have Come from and Where We Are Going.

Health &amp; social work
2024

Segmental areas of denervation in post-polio syndrome.

Arquivos de neuro-psiquiatria
2024

Changes in self-perceived performance and satisfaction with performance of daily activities following interdisciplinary rehabilitation in people with late effects of polio.

NeuroRehabilitation
2024

Post-polio syndrome is not a dysimmune condition.

European journal of physical and rehabilitation medicine
2024

[Congenital malformations of the brain misinterpreted as sequelae of poliomyelitis].

Zeitschrift fur Gerontologie und Geriatrie
2024

[Interdisciplinary multimodal pain therapy in postviral syndromes and ME/CFS : Features, pitfalls and model concept].

Schmerz (Berlin, Germany)
2025

Spontaneous pulmonary herniation in post-polio syndrome.

Journal of ultrasound
2023

Primary total knee arthroplasty in patients with post-polio syndrome.

The bone &amp; joint journal
2023

Congenital Lumbosacral Malformations with Low-Grade Neuroepithelial Tumor Causing Progressive Postpoliomyelitis Paralytic Limb.

Annals of neurology
2023

The risk of post-polio syndrome among immigrant groups in Sweden.

Scientific reports
2023

Assessing pain-the invisible, long-haul polio symptom.

Nursing
2023

Prosthesis for bilateral equinus foot: A case study.

Prosthetics and orthotics international
2023

Functional exercise capacity in maximal and submaximal activities of individuals with polio sequelae.

European journal of applied physiology
2022

Ultrasonography Assessment Based on Muscle Thickness and Echo Intensity in Post-Polio Patients.

Diagnostics (Basel, Switzerland)
2023

Coexistence of fibromyalgia and post-polio syndrome in persons with prior poliomyelitis in Turkey: the relations with symptoms, polio-related impairments, and quality of life.

Disability and rehabilitation
2022

Reliability of Muscle Strength and Muscle Power Assessments Using Isokinetic Dynamometry in Neuromuscular Diseases: A Systematic Review.

Physical therapy
2022

COVID-19 and post-poliomyelitis syndrome: coincidence?

Ideggyogyaszati szemle
2022

Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report.

Journal of dental anesthesia and pain medicine
2022

Describing post-polio syndrome.

Neurologia
2022

The Meaning of Sense of Coherence (SOC) in Persons with Late Effects of Polio-A Qualitative Study.

International journal of environmental research and public health
2022

Postpolio Syndrome from Non-paralytic Poliovirus Infection.

Internal medicine (Tokyo, Japan)
2022

Spinal cord gray matter atrophy is associated with functional decline in post-polio syndrome.

European journal of neurology
2021

Sixty-nine years after surviving the polio epidemic.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
2021

Treatment with L-Citrulline in patients with post-polio syndrome: A single center, randomized, double blind, placebo-controlled trial.

Neuromuscular disorders : NMD
2022

Sense of coherence and coping behaviours in persons with late effects of polio.

Annals of physical and rehabilitation medicine
2021

Spread of vimentin-immunoreactive cells within the plaque-like lesion in the spinal anterior horn of a patient with post-poliomyelitis syndrome.

Neuropathology : official journal of the Japanese Society of Neuropathology
2021

[Post-polio Syndrome in the Perioperative Phase].

Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
2021

Knowledge of healthcare professionals about poliomyelitis and postpoliomyelitis: a cross-sectional study.

Sao Paulo medical journal = Revista paulista de medicina
2021

Fall-Related Activity Avoidance among Persons with Late Effects of Polio and Its Influence on Daily Life: A Mixed-Methods Study.

International journal of environmental research and public health
2021

Pandemics Shaping our World.

Physical medicine and rehabilitation clinics of North America
2021

Medical Comorbidities and Complications Associated with Poliomyelitis and Its Sequelae.

Physical medicine and rehabilitation clinics of North America
2021

Palliative Care for Polio and Postpolio Syndrome.

Physical medicine and rehabilitation clinics of North America
2021

Psychiatric Approaches and Outcomes.

Physical medicine and rehabilitation clinics of North America
2021

Joint and Back Pain: Medications and Role of Injection Therapy for Destructive Joint.

Physical medicine and rehabilitation clinics of North America
2021

Nerve Conduction Study/Electromyography: Common Neuropathies and Considerations for Patients with Polio.

Physical medicine and rehabilitation clinics of North America
2021

Bracing: Upper and Lower Limb Orthoses.

Physical medicine and rehabilitation clinics of North America
2021

Approach to Fatigue and Energy Conservation.

Physical medicine and rehabilitation clinics of North America
2021

The Current State: Epidemiology and Working Toward Eradication.

Physical medicine and rehabilitation clinics of North America
2021

Unilateral chilblains affecting the lower limb with post-polio residual paralysis: An example of immunocompromised cutaneous district.

Indian journal of dermatology, venereology and leprology
2021

Effectiveness of Intravenous Immunoglobulin for Management of Pain in Patients with Postpolio Syndrome.

Pain research &amp; management
2021

Imaging as an alternate diagnostic modality in a presumptive case of abdominopelvic TB in a COVID-19 patient.

BMJ case reports
2021

Extra-motor manifestations in post-polio syndrome (PPS): fatigue, cognitive symptoms and radiological features.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2021

Prevalence and Effect of Obesity on Mobility According to Different Criteria in Polio Survivors.

American journal of physical medicine &amp; rehabilitation
2020

Postpoliomyelitis Syndrome and Reversal With Sugammadex: A Case Report.

AANA journal
2020

Updated size index valid for both neurogenic and myogenic changes.

Muscle &amp; nerve
2020

Effects of the Interactive Videogame Nintendo Wii Sports on Upper Limb Motor Function of Individuals with Post-Polio Syndrome: A Randomized Clinical Trial.

Games for health journal
2020

Usefulness of Neuromuscular Co-morbidity, Left Bundle Branch Block, and Atrial Fibrillation to Predict the Long-Term Prognosis of Left Ventricular Hypertrabeculation/Noncompaction.

The American journal of cardiology
2020

Post-Polio Syndrome Causing Late Onset Respiratory Failure.

The Israel Medical Association journal : IMAJ
2020

Self-reported impairments among people with late effects of polio: a mixed-methods study.

Journal of rehabilitation medicine
2021

Corticomotor Excitability in Two Kinds of Motor Neuron Diseases: A Study on the Patients With Amyotrophic Lateral Sclerosis and Poliomyelitis Survivors.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
2020

Management Options and Outcomes for Patients with Femoral Fractures with Post-Polio Syndrome of the Lower Extremity: A Critical Analysis Review.

JBJS reviews
2020

Longitudinal associations between physical activity, anxiety, and depression in adults with long-term physical disabilities.

Health psychology : official journal of the Division of Health Psychology, American Psychological Association
2020

A twelve-week, four-arm, randomized, double-blind, placebo-controlled, phase 2 prospective clinical trial to evaluate the efficacy and safety of an anthroposophic multimodal treatment on chronic pain in outpatients with postpolio syndrome.

Brain and behavior
2020

Cross-lagged longitudinal analysis of pain intensity and sleep disturbance.

Disability and health journal
2020

A very long-term longitudinal follow-up of persons with late effects of polio.

European journal of physical and rehabilitation medicine
2019

Kaposi sarcoma in a patient with postpolio syndrome.

Cutis
2020

Sleep disorders in aging polio survivors: A systematic review.

Annals of physical and rehabilitation medicine
2019

Goal Pursuit, Goal Adjustment, and Pain in Middle-Aged Adults Aging With Physical Disability.

Journal of aging and health
2019

Polio and post-polio syndrome in non-Western immigrants: A new challenge for the healthcare system in Norway.

Journal of rehabilitation medicine
2020

Resilience and Function in Adults With Chronic Physical Disabilities: A Cross-Lagged Panel Design.

Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
2020

Sense of Coherence and the Association with Sociodemographics and Disability Related Factors in Persons with Late Effects of Polio.

PM &amp; R : the journal of injury, function, and rehabilitation
2019

Secondary health conditions and social role satisfaction in adults with long-term physical disability.

Health psychology : official journal of the Division of Health Psychology, American Psychological Association
2020

Test-Retest Reliability of the Reintegration to Normal Living Index (RNL-I) to Assess Perceived Participation in Adults With Late Effects of Polio.

PM &amp; R : the journal of injury, function, and rehabilitation
2019

Motor Unit Number Index (MUNIX) as a biomarker of motor unit loss in post-polio syndrome versus needle EMG.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology
2018

Neurological Symptoms in Danes with a History of Poliomyelitis: Lifelong Follow-Up of Late Symptoms, their Association with Initial Symptoms of Polio, and Presence of Postpolio Syndrome.

European neurology
2019

Efficacy of Oral Care Provided by Interprofessional Collaboration for a Patient with Esophageal Cancer Associated with Post-polio Syndrome during Neoadjuvant Chemotherapy.

Acta medica Okayama
2018

Psychometric Properties of Three Fatigue Rating Scales in Individuals With Late Effects of Polio.

Annals of rehabilitation medicine
2018

Anxiety, depression, and function in individuals with chronic physical conditions: A longitudinal analysis.

Rehabilitation psychology
2019

Bone Mineral Density Among Individuals With Residual Lower Limb Weakness After Polio.

PM &amp; R : the journal of injury, function, and rehabilitation
2018

[Polio and post-polio syndrome, viewed by patients and health professionals in primary care].

Revista espanola de salud publica
2018

Post-polio syndrome and the late effects of poliomyelitis: Part 2. treatment, management, and prognosis.

Muscle &amp; nerve
2018

Postpolio syndrome and the late effects of poliomyelitis. Part 1. pathogenesis, biomechanical considerations, diagnosis, and investigations.

Muscle &amp; nerve
2018

Problems in Comparing Jitter Values Obtained with Voluntary Activation and Electrical Stimulation.

Journal of neuromuscular diseases
2019

Whole body vibration on people with sequelae of polio.

Physiotherapy theory and practice
2018

Ultrasound-Guided Carpal Tunnel Release Using Dynamic Expansion of the Transverse Safe Zone in a Patient With Postpolio Syndrome: A Case Report.

PM &amp; R : the journal of injury, function, and rehabilitation
2018

[Beneficial Effect of Medical Cannabis in the Treatment of a Pharmacoresistant Nausea Associated with a Somatoform Disorder in a Patient with Post-Polio Syndrome].

Deutsche medizinische Wochenschrift (1946)
2018

Sense of Coherence in persons with late effects of polio.

NeuroRehabilitation
2018

Repetitive transcranial magnetic stimulation in treatment of post polio syndrome.

Neurologia i neurochirurgia polska
2018

Restless legs syndrome is highly prevalent in patients with postpolio syndrome.

Sleep medicine
2019

Polio survivors perceptions of a multi-disciplinary rehabilitation programme.

Disability and rehabilitation
2017

Restless legs syndrome is highly prevalent in patients with post-polio syndrome.

Sleep medicine
2017

Perceived consequences of ageing with late effects of polio and strategies for managing daily life: a qualitative study.

BMC geriatrics
2017

Gait patterns in association with underlying impairments in polio survivors with calf muscle weakness.

Gait &amp; posture
2017

Comparison of activity and fatigue of the respiratory muscles and pulmonary characteristics between post-polio patients and controls: A pilot study.

PloS one
2017

Revealing enterovirus infection in chronic human disorders: An integrated diagnostic approach.

Scientific reports
2018

Measuring Physical and Cognitive Fatigue in People With Post-Polio Syndrome: Development of the Neurological Fatigue Index for Post-Polio Syndrome (NFI-PP).

PM &amp; R : the journal of injury, function, and rehabilitation
2017

Cognitive behavioural therapy for reducing fatigue in post-polio syndrome and in facioscapulohumeral dystrophy: A comparison.

Journal of rehabilitation medicine
2017

Post-Polio-Like Syndrome.

The American journal of medicine
2017

Accounting for polio survivors in the post-polio world.

Lancet (London, England)
2017

Relationship of depression and medications on incidence of falls among people with late effects of polio.

Physiotherapy theory and practice
2017

Assessment of energy expenditure in individuals with post-poliomyelitis syndrome.

Arquivos de neuro-psiquiatria
2017

Treatment with L-citrulline in patients with post-polio syndrome: study protocol for a single-center, randomised, placebo-controlled, double-blind trial.

Trials
2017

A patient with postpolio syndrome developed cauda equina syndrome after neuraxial anesthesia: A case report.

Journal of clinical anesthesia
2017

Post-polio syndrome. Cases report and review of literature.

Neurologia i neurochirurgia polska
2017

Health related quality of life in Turkish polio survivors: impact of post-polio on the health related quality of life in terms of functional status, severity of pain, fatigue, and social, and emotional functioning.

Revista brasileira de reumatologia
2017

My Sister Ra Died a Hero.

Journal of the American Geriatrics Society
2017

Resilience and Function in Adults With Physical Disabilities: An Observational Study.

Archives of physical medicine and rehabilitation
2016

Intrathecal Analgesic Drug Delivery is Effective for Analgesia in a Patient with Post-Poliomyelitis Syndrome: A Case Report.

The American journal of case reports
2018

Quality of life for post-polio syndrome: a patient derived, Rasch standard scale.

Disability and rehabilitation
2017

Outcomes of total hip replacement in limbs affected by poliomyelitis.

Hip international : the journal of clinical and experimental research on hip pathology and therapy
2016

Do Psychosocial Interventions Improve Quality of Life and Wellbeing in Adults with Neuromuscular Disorders? A Systematic Review and Narrative Synthesis.

Journal of neuromuscular diseases
2016

The genetics of post-polio syndrome - much to be unravelled!

The Indian journal of medical research
2017

Frida Kahlo: Portrait of Chronic Pain.

Physical therapy
2017

Growing Older With a Physical Disability: A Special Application of the Successful Aging Paradigm.

The journals of gerontology. Series B, Psychological sciences and social sciences
2016

What is happening to patients who have had polio? The role of the patient in assessment and management.

Australian family physician
2016

Currents issues in cardiorespiratory care of patients with post-polio syndrome.

Arquivos de neuro-psiquiatria
2016

Aerobic Exercise Training in Post-Polio Syndrome: Process Evaluation of a Randomized Controlled Trial.

PloS one
2017

The Perception of Physical Activity in Ambulatory Persons with Late Effects of Polio: A Qualitative Study.

Journal of aging and physical activity
2016

Pyridostigmine: Postpoliomyelitis Syndrome.

Hospital pharmacy
2016

Survey of young patients with polio and a foreign background at a Swedish post-polio outpatient clinic.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2016

Self-reported incidence and age of onset of chronic comorbid medical conditions in adults aging with long-term physical disability.

Disability and health journal
2016

Experiences and perspectives of patients with post-polio syndrome and therapists with exercise and cognitive behavioural therapy.

BMC neurology
2016

Falls in Korean Polio Survivors: Incidence, Consequences, and Risk Factors.

Journal of Korean medical science
2015

A randomized controlled trial of coenzyme Q10 for fatigue in the late-onset sequelae of poliomyelitis.

Complementary therapies in medicine
2015

Elevated plasma inflammatory mediators in post-polio syndrome: No association with long-term functional decline.

Journal of neuroimmunology
2016

[An autopsy case of progressive generalized muscle atrophy over 14 years due to post-polio syndrome].

Rinsho shinkeigaku = Clinical neurology
2015

People living with post-polio syndrome must not be forgotten.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)
2015

How various self-reported impairments influence walking ability in persons with late effects of polio.

NeuroRehabilitation
2015

Sexual Function, Satisfaction, and Use of Aids for Sexual Activity in Middle-Aged Adults with Long-Term Physical Disability.

Topics in spinal cord injury rehabilitation
2015

[A disease of the distant past: information about poliomyelitis and post- poliomyelitis syndrome in the Spanish/Portuguese press, 1995-2009].

Historia, ciencias, saude--Manguinhos
2015

Immunoglobulin treatment in post-polio syndrome: Identification of responders and non-responders.

Journal of rehabilitation medicine
2015

[Post-polio syndrome - a case report].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
2016

Evaluation of gait symmetry in poliomyelitis subjects: Comparison of a conventional knee-ankle-foot orthosis and a new powered knee-ankle-foot orthosis.

Prosthetics and orthotics international
2016

No Reduction of Severe Fatigue in Patients With Postpolio Syndrome by Exercise Therapy or Cognitive Behavioral Therapy: Results of an RCT.

Neurorehabilitation and neural repair
2015

Factors Associated with Reduced Quality of Life in Polio Survivors in Korea.

PloS one
2015

RE: "Review of Secondary Health Conditions in Post-Polio Syndrome" by McNalley TE, Jenson MP, Truitt AR, Schomer KG, Baylor C, Molton IR: Am J Phys Med Rehabil 2015;94: 139-45.

American journal of physical medicine &amp; rehabilitation
2015

Post poliomyelitis syndrome: A rare sequel of acute poliomyelitis-(Author Reply).

JPMA. The Journal of the Pakistan Medical Association
2015

Post poliomyelitis syndrome: A rare sequel of acute poliomyelitis.

JPMA. The Journal of the Pakistan Medical Association
2015

Treatment for postpolio syndrome.

The Cochrane database of systematic reviews
2015

Men With Late Effects of Polio Decline More Than Women in Lower Limb Muscle Strength: A 4-Year Longitudinal Study.

PM &amp; R : the journal of injury, function, and rehabilitation
2015

Post-poliomyelitis syndrome as a possible viral disease.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
2015

Elevated blood lipids are uncommon in patients with post-polio syndrome--a cross sectional study.

BMC neurology
2015

Does a subgroup of postpolio patients need different management?

Disability and health journal
2016

The rehabilitation plan can support clients' active engagement and facilitate the process of change - experiences from people with late effects of polio participating in a rehabilitation programme.

Disability and rehabilitation
2015

Intravenous immunoglobulin for postpolio syndrome: a systematic review and meta-analysis.

BMC neurology
2015

Multidimensional fatigue inventory and post-polio syndrome - a Rasch analysis.

Health and quality of life outcomes
2015

Feasibility of Lung Volume Recruitment in Early Neuromuscular Weakness: A Comparison Between Amyotrophic Lateral Sclerosis, Myotonic Dystrophy, and Postpolio Syndrome.

PM &amp; R : the journal of injury, function, and rehabilitation
2015

[Wheelchair adjustment: practical advice for the family doctor].

Revue medicale suisse
2015

Intra-rater Reliability of Arm and Hand Muscle Strength Measurements in Persons With Late Effects of Polio.

PM &amp; R : the journal of injury, function, and rehabilitation
2014

[Socio-medical profile of post-polio syndrome patients in center east of Tunisia].

La Tunisie medicale
2015

Resilience predicts functional outcomes in people aging with disability: a longitudinal investigation.

Archives of physical medicine and rehabilitation
2015

Long-standing poliomyelitis and psychological health.

Disability and rehabilitation
2015

Change in physical mobility over 10 years in post-polio syndrome.

Neuromuscular disorders : NMD

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

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Comunidades

Grupos ativos de quem convive com esta doença aqui no Raras

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Doenças relacionadas

Doenças com sintomas parecidos — ajudam quem ainda está buscando diagnóstico

Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Digital twin frameworks for polio and post-polio neurodegeneration: Toward predictive, personalised lifelong neuro-rehabilitation.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology· 2026· PMID 41504968mais citado
  2. Determining the presence of restless legs syndrome in patients with poliomyelitis sequelae and its effect on pain, fatigue, sleep and quality of life.
    Sleep &amp; breathing = Schlaf &amp; Atmung· 2026· PMID 41706359mais citado
  3. [Late-onset sequel states of poliomyelitis (postpolyomelitic syndrome)].
    Revista espanola de salud publica· 2026· PMID 41684311mais citado
  4. Metabolic Syndrome in Ambulatory People With Post-Polio Syndrome, Charcot-Marie-Tooth Disease, and Other Neuromuscular Diseases.
    American journal of physical medicine &amp; rehabilitation· 2026· PMID 40736340mais citado
  5. Low-grade persistent poliovirus infection in long-term polio survivors diagnosed with post-polio syndrome: diagnostic and clinical implications.
    Journal of neurology· 2025· PMID 40913634mais citado
  6. Quality of life and associated factors in tunisian postpoliomyelitis syndrome patients.
    Tunis Med· 2025· PMID 41712791recente
  7. Prosthesis for bilateral equinus foot: A case study.
    Prosthet Orthot Int· 2023· PMID 36701199recente
  8. Reliability of Muscle Strength and Muscle Power Assessments Using Isokinetic Dynamometry in Neuromuscular Diseases: A Systematic Review.
    Phys Ther· 2022· PMID 35899532recente
  9. Prolongation of the effect of a single dose of rocuronium in a patient with postpolio syndrome under desflurane anesthesia: a case report.
    J Dent Anesth Pain Med· 2022· PMID 35693355recente
  10. Knowledge of healthcare professionals about poliomyelitis and postpoliomyelitis: a cross-sectional study.
    Sao Paulo Med J· 2021· PMID 34378735recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:2942(Orphanet)
  2. MONDO:0017416(MONDO)
  3. GARD:4454(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q220188(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Síndrome pós-poliomielite
Compêndio · Raras BR

Síndrome pós-poliomielite

ORPHA:2942 · MONDO:0017416
Prevalência
Unknown
Herança
Not applicable
CID-10
G14
CID-11
Ensaios
2 ativos
Início
Adolescent, Adult, Elderly
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0080040
EuropePMC
Wikidata
Wikipedia
Papers 10a
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