O aneurisma da veia de Galeno é uma forma rara de malformação arteriovenosa na qual o precursor embrionário da veia de Galeno, uma veia na base do cérebro, se dilata, fazendo com que muito sangue corra para o coração. Isso pode levar à insuficiência cardíaca rápida. Outras características podem incluir aumento do perímetro cefálico resultante de hidrocefalia, veias incomumente proeminentes na face e no couro cabeludo, atraso no desenvolvimento, dor de cabeça persistente e outros achados neurológicos. O aneurisma da veia de Galeno é frequentemente reconhecido em uma ultrassonografia no final da gravidez. Em outros casos, é diagnosticado após o nascimento. Embora a causa exata permaneça desconhecida, esta condição parece resultar de um defeito no desenvolvimento fetal inicial. O tratamento visa diminuir o fluxo sanguíneo através da malformação e, ao mesmo tempo, maximizar o suprimento de sangue ao cérebro. São preferidas técnicas cirúrgicas minimamente invasivas, como a embolização endovascular.
Introdução
O que você precisa saber de cara
O aneurisma da veia de Galeno é uma forma rara de malformação arteriovenosa na qual o precursor embrionário da veia de Galeno, uma veia na base do cérebro, se dilata, fazendo com que muito sangue corra para o coração. Isso pode levar à insuficiência cardíaca rápida. Outras características podem incluir aumento do perímetro cefálico resultante de hidrocefalia, veias incomumente proeminentes na face e no couro cabeludo, atraso no desenvolvimento, dor de cabeça persistente e outros achados neurológicos. O aneurisma da veia de Galeno é frequentemente reconhecido em uma ultrassonografia no final da gravidez. Em outros casos, é diagnosticado após o nascimento. Embora a causa exata permaneça desconhecida, esta condição parece resultar de um defeito no desenvolvimento fetal inicial. O tratamento visa diminuir o fluxo sanguíneo através da malformação e, ao mesmo tempo, maximizar o suprimento de sangue ao cérebro. São preferidas técnicas cirúrgicas minimamente invasivas, como a embolização endovascular.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 3 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
Triagem neonatal (Teste do Pezinho)
A triagem neonatal permite diagnóstico precoce e início imediato do tratamento.
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Genes associados
1 gene identificado com associação a esta condição. Padrão de herança: Not applicable.
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, an
Cell membrane
Lymphatic malformation 7
A form of primary lymphedema, a disease characterized by swelling of body parts due to developmental anomalies and functional defects of the lymphatic system. Patients with lymphedema may suffer from recurrent local infections. LMPHM7 is an autosomal dominant form with variable expressivity. Some individuals present with severe non-immune hydrops fetalis, which may cause perinatal demise or fully resolve after the neonatal period. Others present with no edema and have milder clinical features, such as atrial septal defect or varicose veins as adults.
Variantes genéticas (ClinVar)
235 variantes patogênicas registradas no ClinVar.
Vias biológicas (Reactome)
4 vias biológicas associadas aos genes desta condição.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Malformação aneurismática da veia de Galeno
Centros de Referência SUS
24 centros habilitados pelo SUS para Malformação aneurismática da veia de Galeno
Centros para Malformação aneurismática da veia de Galeno
Detalhes dos centros
Hospital Universitário Prof. Edgard Santos (HUPES)
R. Dr. Augusto Viana, s/n - Canela, Salvador - BA, 40110-060 · CNES 0003808
Serviço de Referência
Hospital Infantil Albert Sabin
R. Tertuliano Sales, 544 - Vila União, Fortaleza - CE, 60410-794 · CNES 2407876
Serviço de Referência
Hospital de Apoio de Brasília (HAB)
AENW 3 Lote A Setor Noroeste - Plano Piloto, Brasília - DF, 70684-831 · CNES 0010456
Serviço de Referência
Hospital Estadual Infantil e Maternidade Alzir Bernardino Alves (HIABA)
Av. Min. Salgado Filho, 918 - Soteco, Vila Velha - ES, 29106-010 · CNES 6631207
Serviço de Referência
Hospital das Clínicas da UFG
Rua 235 QD. 68 Lote Área, Nº 285, s/nº - Setor Leste Universitário, Goiânia - GO, 74605-050 · CNES 2338424
Serviço de Referência
Hospital Universitário da UFJF
R. Catulo Breviglieri, Bairro - s/n - Santa Catarina, Juiz de Fora - MG, 36036-110 · CNES 2297442
Atenção Especializada
Hospital das Clínicas da UFMG
Av. Prof. Alfredo Balena, 110 - Santa Efigênia, Belo Horizonte - MG, 30130-100 · CNES 2280167
Serviço de Referência
Hospital Universitário Julio Müller (HUJM)
R. Luis Philippe Pereira Leite, s/n - Alvorada, Cuiabá - MT, 78048-902 · CNES 2726092
Atenção Especializada
Hospital Universitário João de Barros Barreto
R. dos Mundurucus, 4487 - Guamá, Belém - PA, 66073-000 · CNES 2337878
Serviço de Referência
Hospital Universitário Lauro Wanderley (HULW)
R. Tabeliao Estanislau Eloy, 585 - Castelo Branco, João Pessoa - PB, 58050-585 · CNES 0002470
Atenção Especializada
Instituto de Medicina Integral Prof. Fernando Figueira (IMIP)
R. dos Coelhos, 300 - Boa Vista, Recife - PE, 50070-902 · CNES 0000647
Serviço de Referência
Hospital Pequeno Príncipe
R. Des. Motta, 1070 - Água Verde, Curitiba - PR, 80250-060 · CNES 3143805
Serviço de Referência
Hospital Universitário Regional de Maringá (HUM)
Av. Mandacaru, 1590 - Parque das Laranjeiras, Maringá - PR, 87083-240 · CNES 2216108
Atenção Especializada
Hospital de Clínicas da UFPR
R. Gen. Carneiro, 181 - Alto da Glória, Curitiba - PR, 80060-900 · CNES 2364980
Serviço de Referência
Hospital Universitário Pedro Ernesto (HUPE-UERJ)
Blvd. 28 de Setembro, 77 - Vila Isabel, Rio de Janeiro - RJ, 20551-030 · CNES 2280221
Serviço de Referência
Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira (IFF/Fiocruz)
Av. Rui Barbosa, 716 - Flamengo, Rio de Janeiro - RJ, 22250-020 · CNES 2269988
Serviço de Referência
Hospital São Lucas da PUCRS
Av. Ipiranga, 6690 - Jardim Botânico, Porto Alegre - RS, 90610-000 · CNES 2232928
Serviço de Referência
Hospital de Clínicas de Porto Alegre (HCPA)
Rua Ramiro Barcelos, 2350 Bloco A - Av. Protásio Alves, 211 - Bloco B e C - Santa Cecília, Porto Alegre - RS, 90035-903 · CNES 2237601
Serviço de Referência
Hospital Universitário da UFSC (HU-UFSC)
R. Profa. Maria Flora Pausewang - Trindade, Florianópolis - SC, 88036-800 · CNES 2560356
Serviço de Referência
Hospital das Clínicas da FMUSP
R. Dr. Ovídio Pires de Campos, 225 - Cerqueira César, São Paulo - SP, 05403-010 · CNES 2077485
Serviço de Referência
Hospital de Base de São José do Rio Preto
Av. Brg. Faria Lima, 5544 - Vila Sao Jose, São José do Rio Preto - SP, 15090-000 · CNES 2079798
Atenção Especializada
Hospital de Clínicas da UNICAMP
R. Vital Brasil, 251 - Cidade Universitária, Campinas - SP, 13083-888 · CNES 2748223
Serviço de Referência
Hospital de Clínicas de Ribeirão Preto (HCRP-USP)
R. Ten. Catão Roxo, 3900 - Vila Monte Alegre, Ribeirão Preto - SP, 14015-010 · CNES 2082187
Serviço de Referência
UNIFESP / Hospital São Paulo
R. Napoleão de Barros, 715 - Vila Clementino, São Paulo - SP, 04024-002 · CNES 2688689
Serviço de Referência
Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
Pesquisa ativa
Ensaios clínicos abertos e novidades científicas recentes
Ensaios em destaque
Pesquisa e ensaios clínicos
4 ensaios clínicos encontrados, 2 ativos.
Publicações mais relevantes
From fetal cardiac axis deviation to postnatal neurovascular diagnosis: road to a diagnosis of vein of Galen malformation.
Fetal Vein of Galen Malformation-Reply.
Fetal Vein of Galen Malformation.
Endoscopic Third Ventriculostomy for Adjunctive Management of Hydrocephalus Associated With Previously Embolized Vein of Galen Malformations.
Hydrocephalus is a comorbid condition in patients with vein of Galen malformations (VOGMs), and its management is complicated by venous hypertension, elevating surgical risk. Endoscopic third ventriculostomy (ETV) is commonly used for cerebrospinal fluid (CSF) diversion in children, but there are limited available data on its efficacy and safety for patients with VOGM. We aimed to review our experiences with ETV across 2 high-volume centers for VOGM patients with hydrocephalus. A two-center retrospective review identified all patients with VOGM who underwent ETV. Demographics, clinical presentation, procedural history, and outcomes were reviewed. ETV success scores were calculated. Twelve patients with VOGM underwent ETV; 66.7% was male, with a median age of 6 months. Seven (58.3%) were still undergoing VOGM embolization before ETV, and 4 had a history of hydrocephalus with acute-on-chronic exacerbation. Eight patients (66.7%) presented with obstructive hydrocephalus because of aqueductal stenosis (58.3%) and with intraventricular hemorrhage without CSF pathway stenosis (8.3%). Three (25.0%) required external ventricular drain placement or fontanelle taps pre-ETV, and choroid plexus cauterization was performed in 4 patients (33.3%). Technical success of ETV was achieved in all cases. One patient experienced venous bleeding at the ventriculostomy site. Postoperative complications occurred in 2 patients: one with transient truncal ataxia and the other with seizure activity, all of which resolved by discharge. At most recent follow-up, 10 patients (83.3%) have minimal residual arteriovenous shunting of their VOGM. The mean ETV success score was 60.8, and 11 patients (91.7%) experienced clinical improvement with ETV patency at the 6-month follow-up. One patient required conversion to a ventriculoperitoneal shunt because of lack of improvement at 6 months. This largest-to-date series on VOGM-associated hydrocephalus treated with ETV demonstrates high safety and efficacy across 2 independent high-volume centers. In patients with VOGM demonstrating clinical deterioration secondary to hydrocephalus, ETV with possible choroid plexus cauterization is a viable CSF diversion strategy to consider.
Vein of Galen Malformation with Pial Arteriovenous Fistula in a 12-month-old Child.
Pial arteriovenous fistulas are extremely rare vascular malformations of the brain (accounting for approximately 1.6% of vascular malformations of the brain) and are classified as Galenic and non-Galenic pial fistulas. We present a rare association of a mural-type vein of Galen malformation with a pial fistula involving the precentral branch of the right middle cerebral artery (MCA) in a 12-month-old infant. A 12-month-old preterm male infant, born vaginally with a delayed cry (birth weight 1.2 kg), presented with progressive macrocephaly, recurrent upper respiratory tract infections, developmental delay, and a history of seizures. Neurologically, the child was intact with no focal deficits. He was the firstborn child of a non-consanguineous marriage; maternal antenatal history was notable for polyhydramnios and fetal cardiomegaly detected on antenatal ultrasound. Antenatal scans at 26 and 28 weeks revealed aneurysmal dilation of the vein of Galen. Postnatal transfontanelle ultrasound showed enlarged lateral and third ventricles with a midline cystic lesion exhibiting turbulent flow, suggestive of a high-flow arteriovenous shunt. At 12 months of age, multidetector computed tomography (MDCT)) identified a 37 × 15 mm lobulated soft tissue density in the perimesencephalic/suprasellar region with ventriculomegaly. MRI of the brain confirmed a 35 × 19 × 21 mm flow void in the region of the vein of Galen associated with hydrocephalus, periventricular ooze, and cerebral atrophy. Digital subtraction angiography revealed a mural-type vein of Galen malformation fed by the right posterior choroidal artery, draining into the torcula. Additionally, a separate pial arteriovenous fistula was identified, supplied by the precentral branch of the right MCA, with cortical venous drainage into the superior sagittal sinus. Left sigmoid sinus hypoplasia with redirected venous outflow into the left superior petrosal sinus and cavernous system was noted. Mural-type vein of Galen malformation with concurrent pial arteriovenous fistula. The child was taken up for endovascular embolization. The vein of Galen malformation was embolized using 70% N N-butyl cyanoacrylate (NBCA). Subsequently, transarterial embolization of the right MCA pial fistula was done using coils and Onyx liquid embolic agent in the same sitting. Post-embolization, complete closure of both fistulas was noted. Post-treatment, CT revealed closure of fistulas with no fresh parenchymal abnormality. The child was discharged on postoperative day 6 without any focal deficit. At 3-month follow-up, the patient remained neurologically stable without new deficits, and follow-up MRI was planned.
Publicações recentes
Favourable outcome of a neonate with vein of Galen malformation with concurrent right superior vena cava draining into the left atrium.
🥇 Revisão sistemáticaEndoscopic Third Ventriculostomy for Adjunctive Management of Hydrocephalus Associated With Previously Embolized Vein of Galen Malformations.
Vein of Galen Malformation with Pial Arteriovenous Fistula in a 12-month-old Child.
A Combination Of Vein Of Galen Aneurysmal Malformation And Bovine Aortic Arch In Newborn: A Case Report.
Safety profile of DMSO-based liquid embolic agents for neurointerventional procedures in neonates, infants, and toddlers: a cohort study.
📚 EuropePMC175 artigos no totalmostrando 167
Endoscopic Third Ventriculostomy for Adjunctive Management of Hydrocephalus Associated With Previously Embolized Vein of Galen Malformations.
NeurosurgeryVein of Galen Malformation with Pial Arteriovenous Fistula in a 12-month-old Child.
Asian journal of neurosurgeryA Combination Of Vein Of Galen Aneurysmal Malformation And Bovine Aortic Arch In Newborn: A Case Report.
JNMA; journal of the Nepal Medical AssociationSafety profile of DMSO-based liquid embolic agents for neurointerventional procedures in neonates, infants, and toddlers: a cohort study.
AJNR. American journal of neuroradiologyVein of Galen Aneurysmal Malformation: A Case Report With Insights Into Radiological Diagnosis Using Ultrasonography and Magnetic Resonance Imaging.
CureusEndoscopic Third Ventriculostomy With Choroid Plexus Cauterization Application in the Management of Hydrocephalus in Previously Embolized Vein of Galen Malformations: 2-Dimensional Operative Video.
Operative neurosurgery (Hagerstown, Md.)A scoping review of variations in cerebral Doppler venous waveforms in infants.
NeuroImageFrom fetal cardiac axis deviation to postnatal neurovascular diagnosis: road to a diagnosis of vein of Galen malformation.
BMJ case reportsThe Aortic Flow Reversal Ratio: A Quantitative Adjunct to the Bicêtre Score in Vein of Galen Malformation.
Journal of clinical medicineNeuro-interventional Radiology in Paediatric Patients: An Update.
Cardiovascular and interventional radiologyFetal Vein of Galen Malformation-Reply.
JAMAFetal Vein of Galen Malformation.
JAMAClinically observed RASA1 missense mutants exhibit diverse RasGAP protein behaviors.
bioRxiv : the preprint server for biologyVein of Galen Malformation-Experience of the Last 13 Years in a Reference Center from South-Eastern Europe.
Life (Basel, Switzerland)Spontaneous thrombosis of vein of Galen malformation.
BMJ case reportsVertical Gaze Palsy in Medial Thalamic Infarction Associated with Vein of Galen Malformation: A Case Report.
Asian journal of neurosurgeryPrediction of Neonatal Intensive Care Unit Mortality in Fetuses and Neonates with Vein of Galen Malformation.
AJNR. American journal of neuroradiologyIn Utero Embolization for Fetal Vein of Galen Malformation.
JAMAVein of Galen malformation presenting as progressive macrocephaly in a 12-month-old girl: A case report.
SAGE open medical case reportsClinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryLetter: Modulation of PI3K and MEK Signaling Reverse Vein of Galen Malformation.
NeurosurgeryVein of Galen malformation in a newborn: clinical presentation and imaging insights.
BMJ case reports4D flow MRI for noninvasive monitoring of high-flow vascular malformations in neonates and infants: A feasibility study.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesAxillary Artery Access for Neuroendovascular Procedures in Infants: Where to Go When Femoral Puncture Fails?
NeurointerventionOutcome of a Late Preterm Infant With Prenatally Diagnosed Vein of Galen Malformation.
NeoReviewsVein of Galen Malformation Detected by Newborn Cranial Ultrasound Screen with Conservative Following Up: Case Report.
Journal of medical ultrasoundAssociation of Disease Severity and Cerebral Interventional Complications With Long-Term Neurodevelopmental Outcome in Neonates With Vein of Galen Malformation.
Pediatric neurologyClinical Phenotypes of a Pediatric Cohort with GDF2-Related Hereditary Hemorrhagic Telangiectasia.
Journal of clinical medicineMediolateral Diameter of the Falcine Sinus as a Predictor of Clinical Outcomes in Fetal Vein of Galen Malformations.
StrokeRoutine 36-week scan: diagnosis of fetal abnormalities.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyUltrasound Super-Resolution Imaging of Neonatal Cerebral Vascular Reorganization.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)Evaluation of adherence to the Preferred Reporting of CasE Series in Surgery (PROCESS) 2020 guideline in case series describing endovascular management of vein of Galen malformation demonstrates suboptimal reporting practices.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaUltrasound-guided transuterine coil embolization of a Vein of Galen malformation.
Clinical neurology and neurosurgeryCorrespondence on 'Transumbilical access for neonatal vein of Galen malformation and pial arteriovenous fistula embolization'.
Journal of neurointerventional surgeryCardiovascular profile score (CVPS) and selected cardiac parameters in fetuses with Vein of Galen malformation.
Ginekologia polska[Use of ultrasound in vein of Galen malformation].
Revista medica del Instituto Mexicano del Seguro SocialNeurovascular Malformations in the Fetus and Neonate.
Neuroimaging clinics of North AmericaTransumbilical access for neonatal vein of Galen malformation and pial arteriovenous fistula embolization.
Journal of neurointerventional surgeryAdjunctive venous sinus stenting in transvenous embolization of vein of Galen malformations.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesNeonatal vein of Galen malformation: A rare cause of high-output heart failure.
Journal of paediatrics and child healthReversal of Fetal Compromise Following In Utero Treatment of Vein of Galen Malformation Using Glue.
Prenatal diagnosisIntracranial vein of Galen malformation and its management: A case report.
Medicine internationalIntracranial cerebrovascular lesions on T2-weighted magnetic resonance imaging.
Journal of clinical imaging scienceCerebral Doppler imaging in neonates: A guide for clinical application and diagnosis.
Developmental medicine and child neurologySystemic venous anomalies in a child with a vein of Galen.
Annals of pediatric cardiologyLiterature review and case report: Rare case of successful prenatal detection of Vein of Galen Malformation (VGAM).
European journal of obstetrics & gynecology and reproductive biology: XComparing Vascular Morphology and Hemodynamics in Patients with Vein of Galen Malformations Using Intracranial 4D Flow MRI.
AJNR. American journal of neuroradiologyVein of Galen Malformations.
Neurosurgery clinics of North AmericaEndoluminal Biopsy for Vein of Galen Malformation.
NeurosurgeryMultidisciplinary care of fetal vein of Galen arteriovenous malformation diagnosed via Doppler ultrasound and magnetic resonance imaging: A case report.
Case reports in women's healthChemical abscess post vein of Galen aneurysmal malformation embolisation with ethylene vinyl alcohol copolymer.
SA journal of radiologySpontaneous thrombosis of type II vein of Galen aneurysmal malformation: a case report.
Folia medicaVein of Galen aneurysmal malformation associated with brain abscess: A computed tomography case report.
Radiology case reportsVein of Galen Aneurysmal Malformation: A Case Report and Literature Review.
CureusPrenatal treatment of a vein of Galen malformation by embolization and 1-year follow-up.
American journal of obstetrics and gynecologyAortic Steal Correlates with Acute Organ Dysfunction and Short-Term Outcomes in Neonates with Vein of Galen Malformation.
NeonatologyVein of Galen malformations in the newborn: case series.
Journal of neurosurgery. Case lessonsUnderstanding development of jugular bulb stenosis in vein of galen malformations: identifying metrics of complex flow dynamics in the cerebral venous vasculature of infants.
Frontiers in physiologyThat which is unseen: 3D printing for pediatric cerebrovascular education.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryDoppler Ultrasound Flow Reversal in the Superior Sagittal Sinus to Detect Cerebral Venous Congestion in Vein of Galen Malformation.
AJNR. American journal of neuroradiologySpontaneous thrombosis of vein of Galen malformation managed with surgical resection: a case‑based review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryTransuterine Ultrasound-Guided Fetal Embolization of Vein of Galen Malformation, Eliminating Postnatal Pathophysiology.
StrokeHeart Failure Following Sinus Venosus Defect Closure in a Patient With Vein of Galen Malformation.
JACC. Case reportsRapid ventricular overdrive pacing and other advanced flow-control techniques for the endovascular embolization of vein of galen malformations.
Frontiers in pediatricsPulmonary Hypertension in Infants and Children with Vein of Galen Malformation and Association with Clinical Outcomes.
The Journal of pediatricsInitial experience with Scepter Mini dual lumen balloon for embolization of cerebrovascular diseases.
Journal of cerebrovascular and endovascular neurosurgeryOvercoming roadblocks in clinical innovation via high fidelity simulation: use of a phantom simulator to achieve FDA and IRB approval of a clinical trial of fetal embolization of vein of Galen malformations.
Journal of neurointerventional surgeryUnrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report.
A&A practiceRecurrent Vein of Galen Aneurysmal Malformation as a Presentation of Hereditary Hemorrhagic Telangiectasia.
Molecular syndromologyTricuspid regurgitation and left ventricular eccentricity as a measure of heart failure in the newborn patient with a vein of Galen malformation: illustrative case.
Journal of neurosurgery. Case lessonsVein of Galen Aneurysmal Malformation with Anomalous Right Superior Vena Cava to the Left Atrium Leading to Atypical Clinical and Echocardiographic Findings.
Pediatric cardiologyOutcomes of endovascular embolization for Vein of Galen malformations: An individual participant data meta-analysis.
Frontiers in pediatricsMorphometric evaluation of great vein of Galen and its clinical implications.
Anatomy & cell biologyThe composition of landmark vein of Galen malformation research: the emergence of endovascular treatments.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryEvolution of transvenous embolization in vein of Galen malformation: case series and review of the literature.
Journal of neurointerventional surgeryVein of Galen malformation and cardiopulmonary bypass.
PerfusionBrain Injury in Fetuses with Vein of Galen Malformation and Nongalenic Arteriovenous Fistulas: Static Snapshot or a Portent of More?
AJNR. American journal of neuroradiologyOutcome of Neonates Presenting With Severe Cardiac Failure due to Cerebral Arteriovenous Fistula.
Pediatric neurologyRapid Ventricular Pacing Facilitates Transarterial Embolization in Vein of Galen Malformations.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesHydrocephalus in Vein of Galen Malformations.
Neurology IndiaPulmonary hypertension associated with vein of Galen malformation. Fetal cardiac hemodynamic findings and physiological considerations.
Journal of perinatology : official journal of the California Perinatal AssociationVein of Galen Malformation Manifesting as High-Output Heart Failure.
CureusVein of Galen aneurysm, dilated cardiomyopathy, and slender habitus in a patient with a recurrent pathogenic variant in PACS2.
American journal of medical genetics. Part AHirayama Disease in a Patient with a History of Late-Onset Symptomatic Vein of Galen Aneurysmal Malformation.
Pediatric neurosurgeryManagement of Jugular Bulb Stenosis in Pediatric Vein of Galen Malformation: A Novel Management Paradigm.
Pediatric neurosurgeryInitial experience with the Scepter Mini catheter for the embolization of vascular malformations in the pediatric population.
The neuroradiology journalTransvenous Pressure Monitoring Guides Endovascular Treatment of Vein of Galen Malformation: A Technical Note.
Pediatric neurosurgeryHigh Output Cardiovascular Physiology and Outcomes in Fetal Diagnosis of Vein of Galen Malformation.
Pediatric cardiologyCoil assisted glue embolization to improve safety and accuracy in endovascular management of Vein of Galen patients.
Clinical neurology and neurosurgeryEpidemiology, Diagnostics, and Management of Vein of Galen Malformation.
Pediatric neurologyA cardiopulmonary bypass strategy to support a patient with vein of Galen malformation.
PerfusionScepter mini assisted angiographic cure of a Vein of Galen Malformation with n-butyl cyanoacrylate.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesSpontaneous regression of a vein of Galen aneurysmal malformation in a pediatric patient: illustrative case.
Journal of neurosurgery. Case lessonsSpontaneous thrombosis of a vein of Galen malformation associated with acute sinusitis: a case report.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryNeurovascular disease and syndromes: Diagnosis and therapy in children.
Handbook of clinical neurologyCerebral arteriovenous fistulae.
Handbook of clinical neurologyVein of Galen Malformation.
The New England journal of medicineCerebrovascular Malformations in a Pediatric Hereditary Hemorrhagic Telangiectasia Cohort.
Pediatric neurologyFetal and Neonatal MRI Predictors of Aggressive Early Clinical Course in Vein of Galen Malformation.
AJNR. American journal of neuroradiologyPseudofeeders: sonographic sign of poor prognosis in fetus with vein of Galen malformation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyNeuroangiography: Review of Anatomy, Periprocedural Management, Technique, and Tips.
Seminars in interventional radiologyFactors Contributing to Major Neurological Complications From Vein of Galen Malformation Embolization.
JAMA neurologyCerebral vascular malformations and their imaging modalities.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical NeurophysiologyAn ACVRL1 gene mutation presenting as vein of Galen malformation at prenatal diagnosis.
American journal of medical genetics. Part AEndoscopic Third Ventriculostomy in an Untreated Vein of Galen Malformation Presenting Lately with Acute Obstructive Hydrocephalus.
World neurosurgeryVein of Galen malformation: beyond life or death.
Developmental medicine and child neurologyLong-term outcome of vein of Galen malformation.
Developmental medicine and child neurologyVein of Galen Malformation, a cause of Intracranial Calcification: Case Report and Review of Literature.
Journal of radiology case reportsFlow-directed micro-catheterisation technique over a detachable coil.
BMJ case reportsHeart failure caused by VGAM: a lesson for diagnosis and treatment from a case and literature review.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal ObstetriciansTargeted Neonatal Echocardiography-Guided Therapy in Vein of Galen Aneurysmal Malformation: A Report of Two Cases with a Review of Physiology and Approach to Management.
AJP reportsOutcome of vein of Galen malformation presenting in the neonatal period.
Archives of disease in childhoodVein of Galen Malformations: The Texas Children's Hospital Experience in the Modern Endovascular Era.
Operative neurosurgery (Hagerstown, Md.)Case report on surgical repair of unusual dissection of arterial duct involving main pulmonary artery in a child with vein of Galen malformation.
European heart journal. Case reportsOcclusion of a mural type vein of Galen malformation in a 10-month-old boy with three Woven EndoBridge (WEB 17) and two coils.
BMJ case reportsSerial Quantitative and Qualitative Measurements of Flow in Vein of Galen Malformations Using 4-Dimensional Flow Magnetic Resonance Imaging (Phase Contrast Vastly undersampled Isotropic PRojection).
World neurosurgeryAn unusual cause of cardiac failure in a neonate.
Archives de pediatrie : organe officiel de la Societe francaise de pediatrieEphrinB2-EphB4-RASA1 Signaling in Human Cerebrovascular Development and Disease.
Trends in molecular medicineQuantifying the Intra-Operative Hemodynamic Effects of Glue Embolization in Vein of Galen Malformations.
Proceedings. IEEE International Symposium on Biomedical ImagingMutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation.
NeuronFetal stroke and cerebrovascular disease: Advances in understanding from lenticulostriate and venous imaging, alloimmune thrombocytopaenia and monochorionic twins.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology SocietyPediatric Congenital Cerebrovascular Anomalies.
Journal of neuroimaging : official journal of the American Society of NeuroimagingRight superior caval vein to the left atrium in a child with vein of Galen malformation.
Echocardiography (Mount Kisco, N.Y.)A rare case of spontaneous thrombosis of vein of Galen malformation in a young adult diagnosed on magnetic resonance imaging and digital subtraction angiography.
Neurology IndiaCross-sectional study of a United Kingdom cohort of neonatal vein of galen malformation.
Annals of neurologyOutcome of Neonates with Vein of Galen Malformation Presenting with Severe Heart Failure: A Case Series.
American journal of perinatologyA review of extraaxial developmental venous anomalies of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, venous varices or aneurysmal malformations, and enlarged emissary veins.
Neurosurgical focusMicrosurgical Management of Vascular Malformations of the Pineal Region.
World neurosurgeryVein of Galen Malformation Thrombosis by Single-Stage, 2-Coil Embolization.
World neurosurgeryAnatomy of the deep venous system in vein of Galen malformation and its changes after endovascular treatment depicted by magnetic resonance venography.
Journal of neurointerventional surgeryRepair of Sinus Venosus Defect and Anomalous Pulmonary Veins Associated With Vein of Galen Malformation.
World journal for pediatric & congenital heart surgeryDilated superior vena cava in fetal echocardiographic three-vessel view: what lies ahead?
Heart AsiaVein of Galen malformation: optimizing the management of postneonatal presentations.
Developmental medicine and child neurologyMultimodality Management of Vein of Galen Malformations-An Institutional Experience.
World neurosurgeryAdenosine-induced cardiac standstill for endovascular treatment of pediatric vein of Galen malformations.
Journal of neurosurgery. PediatricsPresentation, course, and outcome of postneonatal presentations of vein of Galen malformation: a large, single-institution case series.
Developmental medicine and child neurologyHuman genetics and molecular mechanisms of vein of Galen malformation.
Journal of neurosurgery. PediatricsDelayed and incomplete treatment may result in dural fistula development in children with Vein of Galen malformation.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciencesGiant vein of Galen malformation in an adult.
Radiology case reportsSuperselective transvenous embolization with Onyx and n-BCA for vein of Galen aneurysmal malformations with restricted transarterial access: safety, efficacy, and technical aspects.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryVein of Galen Aneurysmal Malformation in Neonates Presenting With Congestive Heart Failure.
Child neurology openVein of Galen malformation treated with the Micro Vascular Plug system: case report.
Journal of neurosurgery. PediatricsUncommon second-trimester presentation of vein of Galen malformation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and GynecologyVein of Galen malformation in a neonate: A case report and review of endovascular management.
World journal of clinical pediatricsEctasia of transverse and sigmoid sinuses with vein of Galen malformation.
Neurology IndiaPediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes.
Journal of neurosurgery. PediatricsRetreatment of a choroidal vein of Galen malformation with embolization 42 years after open surgical treatment in the neonatal period.
Journal of neurointerventional surgeryFistulous-type vein of Galen malformation phantom model for endovascular training and research.
Journal of neurointerventional surgerySpontaneous non-thrombotic regression of vein of Galen malformation in a child following shunt surgery.
Neurology IndiaPediatric knowledge update: Approach to the management of vein of Galen aneurysmal malformations in neonates.
Surgical neurology internationalHydrocephalus in vein of Galen malformation. Another paradigm shift in neurosurgery.
Acta neurochirurgicaHydrocephalus in vein of Galen malformation: etiologies and therapeutic management implications.
Acta neurochirurgicaEndovascular management of a vein of Galen aneurysmal malformation in an infant with challenging femoral arterial access.
Journal of neurosurgery. PediatricsMystery case: Intracranial hemorrhage in adult vein of Galen malformation.
NeurologyVein of Galen Malformation and High-output Cardiac Failure.
AnesthesiologySpontaneous thrombosis of a vein of galen malformation.
Asian journal of neurosurgeryOcclusion of Posterior Fossa Dural Sinuses in Vein of Galen Malformation.
AJNR. American journal of neuroradiologyAntenatal diagnosis of aneurysmal malformation of the vein of Galen.
BMJ case reportsA spectrum of intracranial vascular high-flow arteriovenous shunts in RASA1 mutations.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryPediatric central nervous system vascular malformations.
Pediatric radiologyOutcome and complications of endovascular embolization for vein of Galen malformations: a systematic review and meta-analysis.
Journal of neurosurgeryOptimizing cerebrovascular surgical and endovascular procedures in children via personalized 3D printing.
Journal of neurosurgery. PediatricsSafety of neuroangiography and embolization in children: complication analysis of 697 consecutive procedures in 394 patients.
Journal of neurosurgery. PediatricsFetal MRI demonstrating vein of Galen malformations in two successive pregnancies--a previously unreported occurrence.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryVein of galen aneurysmal malformation: prognostic markers depicted on fetal MRI.
The neuroradiology journalRelapsing fetal bilateral hydrothorax, an isolated expression of a vein of Galen aneurysmal malformation.
BMJ case reportsVarying clinical and imaging outcomes in patients with spontaneous thrombosis of vein of Galen malformation--a report of two cases.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- From fetal cardiac axis deviation to postnatal neurovascular diagnosis: road to a diagnosis of vein of Galen malformation.
- Fetal Vein of Galen Malformation-Reply.
- Fetal Vein of Galen Malformation.
- Endoscopic Third Ventriculostomy for Adjunctive Management of Hydrocephalus Associated With Previously Embolized Vein of Galen Malformations.
- Vein of Galen Malformation with Pial Arteriovenous Fistula in a 12-month-old Child.
- Favourable outcome of a neonate with vein of Galen malformation with concurrent right superior vena cava draining into the left atrium.
- A Combination Of Vein Of Galen Aneurysmal Malformation And Bovine Aortic Arch In Newborn: A Case Report.
- Safety profile of DMSO-based liquid embolic agents for neurointerventional procedures in neonates, infants, and toddlers: a cohort study.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:1053(Orphanet)
- MONDO:0015196(MONDO)
- GARD:5467(GARD (NIH))
- Variantes catalogadas(ClinVar)
- Busca completa no PubMed(PubMed)
- Q11766796(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
