Raras
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Síndrome de vasoconstrição cerebral reversível
ORPHA:284388CID-10 · I67.8CID-11 · 8B22.2DOENÇA RARA

A Síndrome da Vasoconstrição Cerebral Reversível (SVCR) é uma condição rara que afeta os vasos sanguíneos do cérebro. Ela se manifesta com dores de cabeça muito fortes, que podem ou não vir acompanhadas de problemas neurológicos específicos (como fraqueza ou dormência em alguma parte do corpo) ou convulsões. Basicamente, ocorre um estreitamento, que é reversível e acontece em vários pontos ou trechos, das artérias do cérebro.

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Introdução

O que você precisa saber de cara

📋

A Síndrome da Vasoconstrição Cerebral Reversível (SVCR) é uma condição rara que afeta os vasos sanguíneos do cérebro. Ela se manifesta com dores de cabeça muito fortes, que podem ou não vir acompanhadas de problemas neurológicos específicos (como fraqueza ou dormência em alguma parte do corpo) ou convulsões. Basicamente, ocorre um estreitamento, que é reversível e acontece em vários pontos ou trechos, das artérias do cérebro.

Pesquisas ativas
2 ensaios
9 total registrados no ClinicalTrials.gov
Publicações científicas
863 artigos
Último publicado: 2026

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
Adult
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: I67.8
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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧠
Neurológico
7 sintomas
🫃
Digestivo
1 sintomas
🩸
Sangue
1 sintomas
❤️
Coração
1 sintomas
🦴
Ossos e articulações
1 sintomas
👁️
Olhos
1 sintomas

+ 12 sintomas em outras categorias

Características mais comuns

90%prev.
Vasoespasmo
Muito frequente (99-80%)
90%prev.
Cefaleia em trovoada
Muito frequente (99-80%)
55%prev.
Enxaqueca
Frequente (79-30%)
55%prev.
Anormalidade em imagem cerebral
Frequente (79-30%)
55%prev.
Cefaleia paroxística recorrente
Frequente (79-30%)
17%prev.
Hemorragia cerebral
Ocasional (29-5%)
24sintomas
Muito frequente (2)
Frequente (3)
Ocasional (14)
Muito raro (5)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 24 características clínicas mais associadas, ordenadas por frequência.

VasoespasmoVasospasm
Muito frequente (99-80%)90%
Cefaleia em trovoadaThunderclap headache
Muito frequente (99-80%)90%
EnxaquecaMigraine
Frequente (79-30%)55%
Anormalidade em imagem cerebralBrain imaging abnormality
Frequente (79-30%)55%
Cefaleia paroxística recorrenteRecurrent paroxysmal headache
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico863PubMed
Últimos 10 anos200publicações
Pico202362 papers
Linha do tempo
2026Hoje · 2026🧪 2012Primeiro ensaio clínico📈 2023Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado1
1Fase 11
·Pré-clínico7
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 9 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Síndrome de vasoconstrição cerebral reversível

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

🟢 Recrutando agora

1 pesquisa recrutando participantes. Converse com seu médico sobre a possibilidade de participar.

Outros ensaios clínicos

9 ensaios clínicos encontrados, 2 ativos.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

🥉Melhor nível de evidência: Relato de caso
Timeline de publicações
662 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 662

#1

Rapidly progressive varicella zoster virus vasculopathy in a chemotherapy- and steroid-immunosuppressed patient with refractory diffuse large B-cell lymphoma: diagnostic and therapeutic challenges.

Blood research2026 Mar 06

Varicella zoster virus (VZV) vasculopathy is a rare but severe neurological complication that frequently results in a reversible cerebral vasoconstriction syndrome (RCVS). Diagnosis is often delayed because early manifestations are nonspecific and radiologic findings often overlap with those of other cerebrovascular disorders. We describe the fatal case of a heavily pretreated 60-year-old man with refractory diffuse large B-cell lymphoma undergoing evaluation for chimeric antigen receptor (CAR) T-cell therapy. The patient developed multifocal intracranial arterial stenosis and an acute infarction during chemotherapy-induced immunosuppression. The initial radiological features suggested RCVS; however, cerebrospinal fluid (CSF) analysis using polymerase chain reaction (PCR) and anti-IgG antibodies confirmed the presence of VZV. Despite intravenous acyclovir and high-dose corticosteroids, the vasculopathy progressed rapidly, resulting in recurrent infarctions, seizures, and death. This case highlights the diagnostic complexity of VZV vasculopathy in immunocompromised patients and underscores the importance of early CSF evaluation, heightened clinical vigilance for opportunistic viral complications, and the potential diagnostic value of vessel wall magnetic resonance imaging (MRI) in differentiating VZV vasculopathy from mimicking conditions such as RCVS.

#2

Reversible cerebral vasoconstriction syndrome in psychiatric settings: Context-dependent diagnostic bias and consultation-liaison psychiatry practice.

PCN reports : psychiatry and clinical neurosciences2026 Mar

Reversible cerebral vasoconstriction syndrome (RCVS) is a potentially life-threatening neurological condition characterized by thunderclap headaches and multifocal cerebral arterial vasoconstriction resolving within 3 months. Context-dependent diagnostic bias in psychiatric settings may delay recognition of life-threatening conditions including RCVS. A 52-year-old Japanese woman with bipolar II disorder stable on lithium developed recurrent thunderclap headaches 9 days after mild COVID-19 infection. Headaches were consistently triggered by hot showers, reached maximal intensity within seconds, and were described as the worst headache of her life. Initial neurosurgical evaluation included non-contrast head CT but attributed symptoms to tension-type headache without vascular imaging. The patient, dissatisfied with this explanation, sought re-evaluation through our psychiatry outpatient clinic. Psychiatric consultation identified characteristic RCVS features, prompting urgent referral to a headache specialist. Magnetic resonance angiography on Day 31 revealed multifocal segmental vasoconstriction confirming RCVS. Calcium channel blocker treatment led to complete symptom resolution with radiological resolution confirmed at Day 100. This case illustrates how context-dependent diagnostic bias can dangerously delay RCVS recognition in psychiatric settings. Thunderclap headache warrants immediate neuroimaging regardless of psychiatric comorbidity. Psychiatric consultation enabled appropriate diagnosis through collaborative evaluation with specialist neurology, underscoring the essential role of consultation-liaison psychiatry at the medical-psychiatric interface.

#3

Serotonin syndrome presenting as severe reversible cerebral vasoconstriction syndrome.

Practical neurology2026 Feb 13

Serotonin syndrome is a life-threatening adverse drug reaction caused by excessive serotonergic activity from therapeutic use, overdose or drug interactions. Its recognition is challenging, as manifestations range from subtle to severe and fatal. Key diagnostic features are autonomic dysfunction, motor hyperactivity and exaggerated reflexes, including clonus. We report a young woman with severe serotonin syndrome due to serotonergic polypharmacy who developed reversible cerebral vasoconstriction syndrome and overlapping posterior reversible encephalopathy syndrome. The diagnosis was initially delayed because attention had focused on her prominent vascular features with severe focal neurological deficits rather than the underlying toxidrome. We diagnosed serotonin syndrome as she developed more characteristic features. This case highlights the importance of considering serotonin syndrome in patients receiving serotonergic medications who develop motor findings, autonomic dysfunction or unexplained neurological deterioration.

#4

Transcranial Doppler in diagnosing and monitoring reversible cerebral vasoconstriction syndrome: a systematic review.

Journal of neurosurgical sciences2026 Feb 10

Digital subtraction angiography is considered the reference standard for diagnosing reversible cerebral vasoconstriction syndrome (RCVS); however, its invasive nature limits routine application. Transcranial Doppler ultrasonography (TCD) represents a noninvasive and bedside-accessible alternative, but its diagnostic and monitoring value in RCVS remains uncertain. A systematic review was conducted in accordance with PRISMA 2020 guidelines. Searches were performed in PubMed, Embase, Cochrane Library, Scopus, and Web of Science up to January 2024. Eligible studies included case reports, case series, and observational designs involving adults with angiographically confirmed reversible vasoconstriction that reported TCD or color-coded sonography parameters (e.g., mean flow velocity, vasospasm). Risk of bias was assessed with ROBINS-I or Joanna Briggs Institute tools. Due to heterogeneity, results were synthesized descriptively. From 709 records, 8 studies encompassing 128 patients were included. TCD demonstrated increased mean flow velocities in the middle cerebral artery during the acute phase of RCVS, with reported peaks up to 146 cm/s, followed by gradual return to baseline within 6-12 weeks. Vasospasm was observed in up to 93.3% of patients, usually peaking between days 13 and 28. The Lindegaard index, ranging from 2.2 to >7, was valuable in distinguishing hyperemia from vasospasm. Serial bedside examinations, often every 24-48 hours during hospitalization, facilitated timely detection and monitoring of evolving hemodynamic changes. Nonetheless, included studies were small, heterogeneous, and methodologically limited. Transcranial Doppler ultrasonography appears promising as a noninvasive method for detecting cerebral vasospasm and monitoring temporal hemodynamic trajectories in RCVS.

#5

Postpartum reversible cerebral vasoconstriction syndrome: a rare but severe cause of postpartum headache.

BMJ case reports2026 Feb 05

Postpartum reversible cerebral vasoconstriction syndrome (RCVS), also known as postpartum cerebral angiopathy, is an uncommon but potentially serious cause of thunderclap headache. Early diagnosis is challenging, and there may be a misdiagnosis due to non-specific clinical presentation and frequently normal initial imaging studies.We report a case of a primigravid woman in her early 30s who developed a sudden, severe holocranial headache on the fourth postpartum day, with no associated neurological findings. Initial head CT, CT angiography, cerebral CT venography and MRI showed no abnormalities. However, digital subtraction angiography (DSA), revealed multifocal segmental narrowing of intracranial arteries, with complete reversibility after 3 months, consistent with RCVS.The patient was treated with oral nimodipine and experienced gradual symptom resolution. There was no complication associated, with no recurrence so far.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC630 artigos no totalmostrando 199

2026

Post-marketing safety of CGRP monoclonal antibodies and gepants: A systematic review of spontaneous reporting system data.

Headache
2026

Rapidly progressive varicella zoster virus vasculopathy in a chemotherapy- and steroid-immunosuppressed patient with refractory diffuse large B-cell lymphoma: diagnostic and therapeutic challenges.

Blood research
2026

Reversible Cerebral Vasoconstriction Syndrome With Ischemic Stroke Underlying Ring Finger Protein 213 Vasculopathy.

Journal of clinical neurology (Seoul, Korea)
2026

Reversible cerebral vasoconstriction syndrome in psychiatric settings: Context-dependent diagnostic bias and consultation-liaison psychiatry practice.

PCN reports : psychiatry and clinical neurosciences
2026

Association between preeclampsia and reversible cerebral vasoconstriction syndrome: A case-control study.

Pregnancy (Hoboken, N.J.)
2026

Serotonin syndrome presenting as severe reversible cerebral vasoconstriction syndrome.

Practical neurology
2026

Transcranial Doppler in diagnosing and monitoring reversible cerebral vasoconstriction syndrome: a systematic review.

Journal of neurosurgical sciences
2026

Normotensive Palpitations in Primary Care Unmasking Pheochromocytoma Complicated by Reversible Cerebral Vasoconstriction Syndrome: A Case Report.

Cureus
2026

Postpartum reversible cerebral vasoconstriction syndrome: a rare but severe cause of postpartum headache.

BMJ case reports
2025

Ruptured Brain Arteriovenous Malformation Coexisting With Reversible Cerebral Vasoconstriction Syndrome: A Case Report.

Cureus
2026

Reversible Cerebral Vasoconstriction Syndrome with Hyperthyroidism: A Case Report.

Internal medicine (Tokyo, Japan)
2026

Systemic Arterial Stiffness in Reversible Cerebral Vasoconstriction Syndrome: A Prospective Case-Control Study.

European journal of neurology
2025

A Case of Transient Central Hypothyroidism Coinciding With Reversible Cerebral Vasoconstriction Syndrome.

Cureus
2026

Concurrent Reversible Cerebral Vasoconstriction Syndrome and Bilateral Vertebral Artery Dissection in the Postpartum Period: A Case Report.

Clinical case reports
2025

Catecholamine-Induced Reversible Cerebral Vasoconstriction Syndrome: An Overlooked Cause of Thunderclap Headache.

Cureus
2025

Reversible Cerebral Vasculopathy Resembling Reversible Cerebral Vasoconstriction Syndrome in a Case of Untreated Basedow's (Graves') Disease.

Cureus
2025

Reversible Cerebral Vasoconstriction Syndrome Triggered by Whole-Body Cryotherapy in a Teenager.

Journal of child neurology
2025

Reversible cerebral vasoconstriction syndrome presenting as thunderclap headache following high-altitude exposure and coca leaf tea consumption.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2025

Refractory Antiphospholipid Syndrome With Thoracic Outlet and Superior Vena Cava Syndromes: A Complex Case of Recurrent Thrombosis.

Cureus
2025

HRT-induced primary headache associated with sexual activity: A case report.

Post reproductive health
2025

Reversible cerebral vasoconstriction syndrome with delayed vasospasms and subdural hematoma after cardiac transplantation: a case report.

Frontiers in cardiovascular medicine
2025

Etoricoxib and its hidden risks: a case-based review of dermatological, hematological, and cardiovascular complications.

EXCLI journal
2025

Perfusion dynamics in reversible cerebral vasoconstriction syndrome.

The journal of headache and pain
2025

Reversible cerebral vasoconstriction syndrome-related headache and delayed cerebral infarction: a mini review.

Frontiers in neuroscience
2025

Association of Increased Central Arterial Stiffness With BBB Disruption in Patients With Reversible Cerebral Vasoconstriction Syndrome.

Neurology
2025

A Pharmacovigilance Study from 2004 to 2024 Utilizing the FDA Adverse Event Reporting System (FAERS) Examines Ischemic Adverse Events Linked to Triptan Use in Migraine Therapy.

Journal of pain research
2025

Bilateral Cluster Headache-like Attack as a Manifestation of Reversible Cerebral Vasoconstriction Syndrome Following Carotid Artery Stenting: A Case Report.

Internal medicine (Tokyo, Japan)
2026

Labor analgesia in pregnant women with reversible cerebral vasoconstriction syndrome managed with magnesium sulfate infusion to prevent exacerbation and recurrence: two case reports.

International journal of obstetric anesthesia
2025

Pediatric Triptan-induced Reversible Cerebral Vasoconstriction Syndrome with Both Hemorrhagic and Ischemic Stroke: Case Report and Literature Review.

NMC case report journal
2025

The Overlap of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome: A Report of a Complex Case and Challenges With Its Management.

Cureus
2025

Short-term effects of air pollution and weather on reversible cerebral vasoconstriction syndrome: a retrospective bicenter study.

Journal of neurology
2025

Outcomes After Reversible Cerebral Vasoconstriction Syndrome With Convexity Subarachnoid Hemorrhage: Individual Patient Data Analysis.

Neurology
2025

Spinal cord reversible cerebral vasoconstriction syndrome.

Proceedings (Baylor University. Medical Center)
2026

Prolonged and recurrent reversible cerebral vasoconstriction syndrome in the postpartum period.

Practical neurology
2025

Reversible Cerebral Vasoconstriction Syndrome Induced by Sumatriptan: A Case Report and Review of Literature.

Journal of community hospital internal medicine perspectives
2025

Atypical Reversible Cerebral Vasoconstriction Syndrome Without Thunderclap Headache: The Crucial Role of Medical History in Its Diagnosis and Management.

Cureus
2025

Cold-Induced Reversible Cerebral Vasoconstriction Syndrome Presenting With Intraventricular Hemorrhage in a Normotensive Patient.

Cureus
2025

Reversible Cerebral Vasoconstriction Syndrome and Marijuana Use: Raising Awareness.

The primary care companion for CNS disorders
2025

Concurrent Extracerebral Vasoconstriction in Patients with Reversible Cerebral Vasoconstriction Syndrome: A Cross-Sectional Study.

Journal of clinical medicine
2025

Factors associated with complications in reversible cerebral vasoconstriction syndrome: A seven-year study at a comprehensive stroke center.

Clinical neurology and neurosurgery
2025

Fatal Reversible Cerebral Vasoconstriction Syndrome: A Complication of Postpartum Haemorrhagic Shock.

Cureus
2025

Regional Differences in Presentation, Cause, and Outcome of Reversible Cerebral Vasoconstriction Syndrome.

Stroke
2025

Early nimodipine treatment in reversible cerebral vasoconstriction syndrome: A serial transcranial Doppler study.

Headache
2025

Navigating the Diagnostic Maze: A Case Report and Narrative Review of Reversible Cerebral Vasoconstriction Syndrome.

Current medical imaging
2025

Leucine-rich glioma-inactivated 1 (LGI-1) autoimmune encephalitis presenting as reversible cerebral vasoconstriction syndrome: Initial case report from India.

Journal of postgraduate medicine
2025

A Case of Postpartum Reversible Cerebral Vasoconstriction Syndrome with Extracranial Artery Involvement.

Acta neurologica Taiwanica
2025

Reversible cerebral vasoconstriction syndrome in idiopathic multicentric Castleman disease under treatment with tocilizumab.

BMJ neurology open
2025

Corticosteroids in posterior reversible encephalopathy syndrome: Friend or foe? A systematic review.

World journal of clinical cases
2025

Beyond the "string of beads": case-based exploration of diagnostic pitfalls and solutions in reversible cerebral vasoconstriction syndrome.

The journal of headache and pain
2025

Hypertension and encephalopathy in a pediatric patient following red blood cell transfusion.

Transfusion
2025

Familial Reversible Cerebral Vasoconstriction Syndrome: Insights From Two Families.

Case reports in neurological medicine
2025

Reversible Cerebral Vasoconstriction Syndrome Secondary to Paroxetine and Opioid Use in a Middle-Aged Woman: A Case Report.

Cureus
2025

Cola-colored Cerebrospinal Fluid: A Case of Reversible Cerebral Vasoconstriction Syndrome.

The Journal of the Association of Physicians of India
2025

An unusual case of hypoxic-ischemic brain injury related to reversible cerebral vasoconstriction syndrome.

Intensive care medicine
2025

Reversible cerebral vasoconstriction syndrome: Transcranial doppler findings in a case series of 90 patients.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2025

Diffuse cerebral vasodilatation at the initial stage of reversible cerebral vasoconstriction syndrome (RCVS).

Revue neurologique
2024

Reversible Cerebral Vasoconstriction Syndrome Secondary to Escitalopram.

Clinical medicine &amp; research
2025

A case report of acute intermittent porphyria presenting with reversible cerebral vasoconstriction syndrome.

Medicine
2025

Unveiling Unconventional Demographics: Reversible Cerebral Vasoconstriction Syndrome in a Young Male With Marijuana Use.

The primary care companion for CNS disorders
2025

Beyond Septic Encephalopathy: A Case Report of Severe RCVS and PRES in a Patient With HLH due to Appendicitis.

The Neurohospitalist
2025

Woman with Recurrent Headaches.

The Journal of emergency medicine
2025

Retrospective analysis of 80 patients diagnosed with reversible cerebral vasoconstriction syndrome in the Helsinki Metropolitan Area.

European journal of neurology
2025

Reversible systemic vasoconstriction syndrome: a new diagnostic family of generalized vasospasm in multiple organs.

Diagnosis (Berlin, Germany)
2025

Clinical Characteristics of COVID-19-Related Reversible Cerebral Vasoconstriction Syndrome: A Systematic Review of Case Series.

Journal of clinical medicine
2025

A reply, drug-induced reversible cerebral vasoconstriction syndrome: Lessons from the real world.

Cephalalgia : an international journal of headache
2025

Drug-induced reversible cerebral vasoconstriction syndrome: Lessons from the real world.

Cephalalgia : an international journal of headache
2025

Predictors of outcome in patients with presumed reversible cerebral vasoconstriction syndrome (RCVS).

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2025

Reversible Cerebral Vasoconstriction Syndrome: A Retrospective study from South India.

Annals of Indian Academy of Neurology
2025

A case report of the thunderclap headache: pearls and pitfalls.

CJEM
2024

Reversible cerebral vasoconstriction syndrome in a methylphenidate-treated patient: a case report.

BMC neurology
2024

Reversible cerebral vasoconstriction syndrome following carotid artery revascularization: About three case reports and review of literature.

Journal de medecine vasculaire
2024

Intracerebral hemorrhage as a complication of reversible cerebral vasoconstriction syndrome in the postpartum periods: a case report.

The Pan African medical journal
2024

Reversible Cerebral Vasoconstriction Syndrome Following Blood Transfusion in a Patient With Chronic Anemia: A Case Report.

Clinical case reports
2024

Real-world study of adverse events associated with triptan use in migraine treatment based on the U.S. Food and Drug Administration (FDA) adverse event reporting system (FAERS) database.

The journal of headache and pain
2025

Reversible cerebral vasoconstriction syndrome secondary to chronic cocaine abuse: Case report.

Radiology case reports
2024

A Pediatric Case of Nonprogressive Idiopathic Central Vasculitis: A Spectrum of Clinical Presentations.

Cureus
2025

Reversible Cerebral Vasoconstriction Syndrome for the Internist-A Narrative Review.

The American journal of medicine
2024

Snakebite-induced reversible cerebral vasoconstriction syndrome: Report of three cases.

Toxicon : official journal of the International Society on Toxinology
2025

Reversible cerebral vasoconstriction syndrome and bilateral Eagle Syndrome cause recurrent reversible carotid artery stenosis and cerebral infarction.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2024

Reversible Cerebral Vasoconstriction Syndrome without Headache.

The journal of medical investigation : JMI
2024

Treatment-Related Reversible Cerebral Vasoconstriction Syndrome.

Journal of clinical medicine
2024

Convexity subarachnoid hemorrhage revealed contralateral internal carotid artery dissection due to Eagle syndrome: a case report.

BMC neurology
2024

Reversible cerebral vasoconstriction syndrome after intravenous immunoglobulin: a rare cause of headache and sudden onset weakness in a patient with Guillain-Barre syndrome.

BMJ case reports
2024

Cerebral Artery Vasoconstriction After Galcanezumab Loading Dose for Migraine Prevention: A Case Report.

Pain and therapy
2024

Management of Psychiatric Diagnoses in Reversible Cerebral Vasoconstriction Syndrome: The Dangers of Worsening Pathology with Serotonergic Medications: A Case Report and Literature Review.

Journal of psychiatric practice
2025

Hyperdense Vessel Sign in Brain Computed Tomography as an Early Indication of Reversible Cerebral Vasoconstriction Syndrome.

Internal medicine (Tokyo, Japan)
2024

Hemorrhagic versus non-hemorrhagic presentation of presumed reversible cerebral vasoconstriction syndrome (RCVS): Presentations and outcomes.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
2024

A Rare Case of Idiopathic Reversible Cerebral Vasoconstriction Syndrome.

The American journal of case reports
2024

Etiology and characteristics of non-aneurysmal thunderclap headache presenting to an acute setting.

The American journal of emergency medicine
2024

Preeclampsia and Severe Metabolic Alkalosis as Co-morbid Factors in Reversible Cerebral Vasoconstriction Syndrome: A Case Report.

The Israel Medical Association journal : IMAJ
2024

[RCVS: case-study and role of substance abuse, Covid and psychotropic drugs].

Tijdschrift voor psychiatrie
2024

Approach to Altered Mental Status in Pregnancy and Postpartum.

Seminars in neurology
2024

When transfusion causes a splitting headache: A case report and rapid review of transfusion-associated reversible cerebral vasoconstriction syndrome.

Transfusion
2024

Acute Intermittent Porphyria Presenting with Posterior Reversible Encephalopathy Syndrome, Reversible Cerebral Vasoconstriction Syndrome and Myocardial Ischemia: A Case Report and Review.

Psychology research and behavior management
2024

Drugs associated with reversible cerebral vasoconstriction syndrome: A pharmacovigilance study in vigiBase®.

Cephalalgia : an international journal of headache
2024

Spontaneous Non-Aneurysmal Convexity Subarachnoid Hemorrhage: A Scoping Review of Different Etiologies beyond Cerebral Amyloid Angiopathy.

Journal of clinical medicine
2024

Reversible cerebral vasoconstriction syndrome post-cardiac transplantation: a therapeutic dilemma: case report.

BMC neurology
2024

Reversible cerebral vasoconstriction syndrome due to teprotumumab: two case reports.

Oxford medical case reports
2024

Pathological Laughter: The First Manifestation of Intracerebral Haemorrhage Linked to Phenylephrine Overuse.

Cureus
2024

Neuropsychological aspects of reversible cerebral vasoconstriction syndrome.

Dementia &amp; neuropsychologia
2024

[Reversible cerebral vasoconstriction syndrome. Recurrence of thunderclap headaches after treatment with corticosteroids].

Revista de neurologia
2024

Neurological Complications of Cannabinoids.

Seminars in neurology
2024

[Reversible cerebral vasoconstriction syndrome : A rare cause of stroke].

Der Nervenarzt
2024

Cerebrospinal Fluid Proteome Map Reveals Molecular Signatures of Reversible Cerebral Vasoconstriction Syndrome.

Molecular &amp; cellular proteomics : MCP
2024

Radiological Findings in Reversible Cerebral Vasoconstriction Syndrome: A Systematic Review of Literature.

Cureus
2024

An Autopsy Case of Reversible Cerebral Vasoconstriction Syndrome After a Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination.

Cureus
2024

Glue embolization of ruptured pseudoaneurysm secondary to reversible cerebral vasoconstriction syndrome: An illustrative case.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
2024

Sex-based difference in selected stroke etiologies: cerebral dural sinus venous thrombosis, reversible cerebral vasoconstriction syndrome, dissection, migraine, pregnancy/puerperium/OC use.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2024

Reversible Cerebral Vasoconstriction Syndrome Mimicking Eclampsia.

Cureus
2024

Reversible Cerebral Vasoconstriction Syndrome Secondary to Loperamide Ingestion: A Case Report.

The Neurohospitalist
2024

Recurrent thunderclap headache after endovascular embolization of pial AV malformation by onyx material.

Clinical neurology and neurosurgery
2025

Unmasking the Imitators: Challenges in Identifying Intracranial Atherosclerosis-Related Large Vessel Occlusion Mimics During Mechanical Thrombectomy.

Stroke (Hoboken, N.J.)
2024

Pediatric Reversible Cerebral Vasoconstriction Syndrome/Posterior Encephalopathy Syndrome/Poststreptococcal Glomerulonephritis.

Pediatric neurology
2024

Reversible Cerebral Vasoconstriction Syndrome With Typical and Atypical Symptoms: A Case Series.

Cureus
2023

PRIMARY ANGIITIS OF THE CENTRAL NERVOUS SYSTEM - A DIAGNOSTIC CHALLENGE.

Acta clinica Croatica
2024

Primary and Secondary Intracerebral Hemorrhage in Pregnant and Nonpregnant Young Adults by SMASH-UP Criteria.

Journal of the American Heart Association
2024

Concurrent spontaneous coronary dissection and reversible cerebral vasoconstriction syndrome during postnatal care.

The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology
2024

Stroke without cerebral arteriopathy in sickle cell disease children: causes and treatment.

Haematologica
2024

Reversible cerebral vasoconstriction syndrome shows different clinical pictures at different times during the perinatal period: Two case reports.

Taiwanese journal of obstetrics &amp; gynecology
2024

Frequency of ischaemic stroke and intracranial haemorrhage in patients with reversible cerebral vasoconstriction syndrome (RCVS) and posterior reversible encephalopathy syndrome (PRES) - A systematic review.

European journal of neurology
2024

The prevalence of non-contrast CT imaging abnormalities in reversible cerebral vasoconstriction syndrome: A systematic review and meta-analysis.

PloS one
2024

Reversible cerebral vasoconstriction syndrome and posterior reversible encephalopathy syndrome following vaccination: analysis of the VAERS database and systematic review.

Annals of medicine and surgery (2012)
2024

Predictors of angiographic resolution in patients with presumed reversible cerebral vasoconstriction syndrome.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
2024

Case report: Neuronal intranuclear inclusion disease initially mimicking reversible cerebral vasoconstriction syndrome: serial neuroimaging findings during an 11-year follow-up.

Frontiers in neurology
2024

Immunochemotherapy triggered reversible cerebral vasoconstriction syndrome in a patient with intravascular large B-cell lymphoma.

Leukemia &amp; lymphoma
2024

Clinical relevance of reversible cerebral vasoconstriction syndrome in pregnant women with posterior reversible encephalopathy syndrome: review of case reports in Japan.

Hypertension research : official journal of the Japanese Society of Hypertension
2024

Unusual Presentation of Reversible Transient Vision Loss After Caesarean Section Under Subarachnoid Block: A Case Report.

Cureus
2024

Reversible Cerebral Vasoconstriction Syndrome and Female Sex: A Narrative Review.

Stroke
2024

Clinical Reasoning: A 54-Year-Old Woman With Progressive Headache and Neurologic Decline.

Neurology
2024

Dynamic changes in glymphatic function in reversible cerebral vasoconstriction syndrome.

The journal of headache and pain
2024

A case report on concomitant reversible cerebral vasoconstriction syndrome and transient global amnesia.

Cortex; a journal devoted to the study of the nervous system and behavior
2023

[Reversible cerebral vasoconstriction syndrome and ischemic stroke].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2023

Association between impaired dynamic cerebral autoregulation and BBB disruption in reversible cerebral vasoconstriction syndrome.

The journal of headache and pain
2023

Unilateral Basal Ganglia Hemorrhage and Lateral Rectus Palsy: An Unusual Association in Marijuana-Induced Reversible Cerebral Vasoconstriction Syndrome.

Annals of Indian Academy of Neurology
2023

[A case of acute bilateral blindness presumably caused by reversible cerebral vasoconstriction syndrome after traumatic brain injury].

Rinsho shinkeigaku = Clinical neurology
2023

Reversible cerebral vasoconstriction syndrome related to extracranial dissection associated with COVID-19: an immunological trigger?

Einstein (Sao Paulo, Brazil)
2024

Reversible Cerebral Vasoconstriction Syndrome And Fibromuscular Dysplasia: An Epiphenomenon Or A Causal Relationship?

Acta neurologica Taiwanica
2024

Imaging of Reversible Cerebral Vasoconstriction Syndrome and Posterior Reversible Encephalopathy Syndrome.

Neuroimaging clinics of North America
2023

Reversible cerebral vasoconstriction syndrome following intracranial hypotension in a postpartum patient: a case report and literature review.

Frontiers in neurology
2023

Reversible Cerebral Vasoconstriction Syndrome Associated With Oxybutynin Use; a Brief Review of Pathophysiology.

Journal of community hospital internal medicine perspectives
2023

Ultrasonographic Vasospasm and Outcome of Posterior Reversible Encephalopathy and Cerebral Vasoconstriction Syndromes.

Ultraschall in der Medizin (Stuttgart, Germany : 1980)
2023

Reversible cerebral vasoconstriction syndrome after neostigmine and atropine administration for postdural puncture headache.

British journal of anaesthesia
2023

Guillain-Barré Syndrome Complicated by Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome.

European journal of case reports in internal medicine
2023

A case report of reversible cerebral vasoconstriction syndrome with thunderclap headache significantly exacerbated in the supine position and alleviated in the standing position.

BMC neurology
2023

Reversible Cerebral Vasoconstriction Syndrome and Raynaud's Phenomenon: Is There a Link between the Pathogeneses of Their Underlying Complex Etiology? A Case Report and Literature Review.

Diagnostics (Basel, Switzerland)
2023

Misdiagnosis of Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome in the Emergency Department.

Journal of the American Heart Association
2023

Magnesium deficiency: An overlooked key to the puzzle of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS)?

Journal of the neurological sciences
2023

Reversible Cerebral Vasoconstriction Syndrome Exacerbation After Calcitonin Gene-Related Peptide Inhibitor Administration.

The Neurohospitalist
2023

Headache Attributed to Reversible Cerebral Vasoconstriction Syndrome (RCVS).

Diagnostics (Basel, Switzerland)
2024

Reversible cerebral vasoconstriction syndrome in Guillain-Barre syndrome: a case report and literature review.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

Recurrent Reversible Cerebral Vasoconstriction Syndrome: A Report of Two Cases.

Cureus
2023

Intrathecal Nicardipine for Severe Intractable Reversible Cerebral Vasoconstriction Syndrome: A Novel Case Report.

Cureus
2023

Case report: Meningitis: a cause of reversible cerebral vasoconstriction syndrome?

Frontiers in neurology
2023

Management of postoperative cerebral vasospasm in skull base surgeries: A systematic review of case reports and series.

Surgical neurology international
2023

Reversible cerebral vasoconstriction syndrome associated with Chikungunya infection.

BMJ case reports
2024

Recurrent reversible cerebral vasoconstriction syndrome and antiphospholipid syndrome.

Acta neurologica Belgica
2023

Posterior Reversible Leucoencephalopathy Syndrome: Case Series, Comments, and Diagnostic Dilemma.

Current neurology and neuroscience reports
2023

Disrupted Brain Functional Status in Patients with Reversible Cerebral Vasoconstriction Syndrome.

Annals of neurology
2023

Clinical Images: Symmetrical Gyriform Restricted Diffusion in Severe Reversible Cerebral Vasoconstriction Syndrome.

World neurosurgery
2023

Reversible cerebral Vasoconstriction syndrome intERnational CollaborativE (REVERCE) network: Study protocol and rationale of a multicentre research collaboration.

European stroke journal
2023

Vessel wall imaging and carotid artery stenting for recurrent cervical internal carotid artery vasospasm syndrome: illustrative case.

Journal of neurosurgery. Case lessons
2023

Pediatric Reversible Cerebral Vasoconstriction Syndrome Related to Pregnancy.

Pediatric neurology
2023

Verapamil in the treatment of reversible cerebral vasoconstriction syndrome: A systematic review.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2023

Advances in Management of the Stroke Etiology One-Percenters.

Current neurology and neuroscience reports
2023

Reversible cerebral vasoconstriction syndrome: A review of pathogenesis, clinical presentation, and treatment.

International journal of stroke : official journal of the International Stroke Society
2023

Severe Cerebral Vasospasm Caused by Acute on Top of Chronic Spontaneous Subdural Hematoma: A Case Report and Review of the Literature.

Cureus
2023

Sudden-onset headache due to reversible cerebral vasoconstriction syndrome.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

COVID-19 and Cerebrovascular Disease.

Seminars in neurology
2023

A Rare Case Report of Acute Neurologic Sequelae in a Young Primigravida With Recent COVID Pneumonia.

Cureus
2023

The Role of High-Resolution Magnetic Resonance Imaging in Cerebrovascular Disease: A Narrative Review.

Brain sciences
2023

'Diagnostic anchoring' and a delayed diagnosis of reversible cerebral vasoconstriction syndrome.

BMJ case reports
2022

Extracranial reversible cerebral vasoconstriction syndrome associated with vertebral artery dissection: A case report.

Brain circulation
2023

Reversible cerebral vasoconstriction syndrome after levonorgestrel-releasing intrauterine device placement-Case report.

Headache
2023

Neurological Adverse Reactions to SARS-CoV-2 Vaccines.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
2023

Convexity subarachnoid haemorrhage: a practical guide.

Practical neurology
2023

Complications of reversible cerebral vasoconstriction syndrome in relation to age.

Journal of neurology
2023

Outcomes in Patients With COVID-19 With Acute Encephalopathy and Coma: An International Prospective Study.

Neurology
2023

Headache and systemic lupus erythematosus: A narrative review.

Headache
2023

Reversible cerebral vasoconstriction syndrome: strategies to early diagnosis and the role of transcranial color-coded doppler ultrasonography (TCCD).

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2023

Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis.

Journal of neurology
2023

Hyperintense vessel sign on magnetic resonance imaging at the time of presentation in reversible cerebral vasoconstriction syndrome.

Clinical neurology and neurosurgery
2023

Reversible cerebral vasoconstriction syndrome in the postpartum period: A case report and review of the literature.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
2023

Posterior Reversible Encephalopathy Syndrome After Thoraco-Abdominal Aortic Replacement.

EJVES vascular forum
2023

Intra-arterial vasodilators infusion for management of reversible cerebral vasoconstriction syndrome in a 12-year-old girl: A case report.

Frontiers in pediatrics
2023

Reversible cerebral vasoconstriction syndrome (RCVS).

QJM : monthly journal of the Association of Physicians
2023

Migration of Vasoconstriction in Reversible Cerebral Vasoconstriction Syndrome.

JMA journal
2023

Update on primary headache associated with sexual activity and primary thunderclap headache.

Cephalalgia : an international journal of headache
2023

Reversible Cerebral Vasoconstriction Syndrome Associated with Vasospasm of the Colic Arteries and Possibly Coronary Vasospasm.

The American journal of case reports
2023

Eclampsia with hypothyroidism complicated with posterior reversible encephalopathy syndrome-a case report.

BMC neurology
2025

Diagnostic yield of cerebral angiography for intracranial hemorrhage in young patients: A single-center retrospective analysis.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
2023

Reversible cerebral vasoconstriction syndrome: literature review.

The Egyptian journal of neurology, psychiatry and neurosurgery
2022

Serial Magnetic Resonance Imaging and Magnetic Resonance Angiographic Findings of Reversible Cerebral Vasoconstriction Syndrome Associated with Postpartum.

Case reports in neurology
2023

Lomerizine Improved Bath-related Headache Presenting as Reversible Cerebral Vasoconstriction Syndrome.

Internal medicine (Tokyo, Japan)
2023

Reversible cerebral vasoconstriction syndrome associated with probable drug poisoning.

Radiology case reports
2023

The link between reversible cerebral vasoconstriction syndrome and transient global amnesia.

Headache
2023

Reversible Cerebral Vasoconstriction Syndrome Triggered by Contact With Water in a Swimmer.

Pain medicine case reports
2023

Adult-onset Leigh Syndrome with a m.9176T>C Mutation Manifested As Reversible Cerebral Vasoconstriction Syndrome.

Internal medicine (Tokyo, Japan)
2022

[Reversible cerebral vasoconstriction syndrome].

La Revue du praticien
2023

Vasoconstriction and long-term headache in reversible cerebral vasoconstriction syndrome.

Journal of neurology
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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Rapidly progressive varicella zoster virus vasculopathy in a chemotherapy- and steroid-immunosuppressed patient with refractory diffuse large B-cell lymphoma: diagnostic and therapeutic challenges.
    Blood research· 2026· PMID 41790173mais citado
  2. Reversible cerebral vasoconstriction syndrome in psychiatric settings: Context-dependent diagnostic bias and consultation-liaison psychiatry practice.
    PCN reports : psychiatry and clinical neurosciences· 2026· PMID 41769064mais citado
  3. Serotonin syndrome presenting as severe reversible cerebral vasoconstriction syndrome.
    Practical neurology· 2026· PMID 41690768mais citado
  4. Transcranial Doppler in diagnosing and monitoring reversible cerebral vasoconstriction syndrome: a systematic review.
    Journal of neurosurgical sciences· 2026· PMID 41665475mais citado
  5. Postpartum reversible cerebral vasoconstriction syndrome: a rare but severe cause of postpartum headache.
    BMJ case reports· 2026· PMID 41644200mais citado
  6. [Headache in cerebrovascular diseases].
    Zh Nevrol Psikhiatr Im S S Korsakova· 2026· PMID 41984555recente
  7. Post-stroke headache: a review of epidemiology, pathophysiology, and clinical management.
    Front Neurosci· 2026· PMID 41929700recente
  8. Focal Cerebral Arteriopathy in a Young Adult.
    Cureus· 2026· PMID 41913875recente
  9. Reversible cerebral vasoconstriction syndrome: A narrative review.
    Headache· 2026· PMID 41902495recente
  10. Post-marketing safety of CGRP monoclonal antibodies and gepants: A systematic review of spontaneous reporting system data.
    Headache· 2026· PMID 41834180recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:284388(Orphanet)
  2. MONDO:0017291(MONDO)
  3. GARD:12768(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q7318292(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Síndrome de vasoconstrição cerebral reversível
Compêndio · Raras BR

Síndrome de vasoconstrição cerebral reversível

ORPHA:284388 · MONDO:0017291
Prevalência
Unknown
Herança
Not applicable
CID-10
I67.8 · Outras doenças cerebrovasculares especificadas
CID-11
Ensaios
2 ativos
Início
Adult
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C3544214
EuropePMC
Wikidata
Wikipedia
Papers 10a
Evidência
🥉 Relato de caso
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