Characterization of ferroportin disease and SLC40A1-related hemochromatosis - Results from the EASL non-HFE registry.

The therapeutic potential of Piezo1 channel-mediated ferroptosis and its inhibitor.

Mitochondrial Iron Handling and Lipid Peroxidation as Drivers of Ferroptosis.

COG5 deficiency disrupts cellular copper homeostasis and underlies the impaired mitochondrial OXPHOS function.

Antibody-based nanoparticles in Alzheimer's disease: Innovations in diagnosis and therapy.

Effect of 6-Hydroxydopamine on Iron Metabolism in MO3.13 Oligodendrocytes.

Placental iron transport under maternal stress: a missing link in foetal programming and mental health.

Astrocyte-Targeted Nanotherapeutics Modulate Iron Homeostasis in Cerebral Amyloid Angiopathy by Restoring the Astrocytic Trafficking Hub Function.

Iron Overload-Induced Ferroptosis Drives Placental Dysfunction in Preeclampsia.

Intestine-Specific Ferroportin Ablation Rescues from Systemic Iron Overload in Mice.

Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder.

[Effect of moxibustion at "Feishu" (BL13) and "Xinshu"(BL15) on myocardial fibrosis in chronic heart failure rats based on ferroptosis].

Prokaryotic organelle mitochondria drive tumorigenesis: "the original sin".

High glucose diet induces hepatic iron overload contributing to metabolic dysfunction.

The adaptation strategy of Astragalus mongholicus shoots to the root Fe2+ deficiency and its strong stimulating effect on glucoliquiritin apioside accumulation.

Effect of saponins from gynostemma pentaphyllum on iron metabolism in apolipoprotein E deficient mice.

The Potential Role of Iron Homeostasis and Ferroptosis in Exercise Nutrition and Health.

Human pluripotent stem cell models of Friedreich's ataxia: innovations, considerations, and future perspectives.

Obesity impairs gut repair via AFABP-mediated iron overload in intestinal stem cells.

Copper-Induced Cell Death in Renal Diseases: Molecular Mechanisms and Therapeutic Implications.

Angiotensin II-Induced Ferroptosis in Epithelial Cells Contributes to Kidney Injury via SP1-DPEP1-Mediated SLC3A2 Degradation.

Iron Balance and Cardiovascular Health: The Double-Edged Role of Deficiency and Overload.

Neuroprotective effects of ZiYin XiFeng formula against Parkinson's disease via Nrf2/SLC7A11/GPX4-mediated ferroptosis inhibition.

N-homocysteinylation of ferritin and associated changes in iron metabolism as potential drivers of vascular endothelial dysfunction in hyperhomocysteinemia.

Therapeutic Potentials of Phytochemicals in Pancreatitis: Targeting Calcium Signaling, Ferroptosis, microRNAs, and Inflammation with Drug-Likeness Evaluation.

Gestational and Lactational Exposure to BPS Triggers Microglial Ferroptosis via the SLC7A11/GPX4 Antioxidant Axis and Induces Memory Impairment in Offspring Mice.

Iron metabolism disorder promotes postovulatory oocyte aging by inducing oxidative stress damage.

Pathophysiological Role and Therapeutic Potential of Vitamin C in Metabolic Syndrome and Type 2 Diabetes Mellitus.

The Non-Coding RNome Landscape in Erythropoiesis: Pathophysiological Implications.

YTHDF1 transcriptionally activated by TCF4 suppresses osteoblast ferroptosis in titanium nanoparticle-induced osteolysis by accelerating GPX4 and SLC7A11 translation.

Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders.

Pharmacogenomic and Clinical Predictors of Deferasirox Response in Transfusion-Dependent Thalassemia Identified Using Whole-Genome Sequencing.

Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus.

Lipidic nanomedicines enhance Hinokitiol activity on human primary macrophages from Ferroportin disease patients.

Evaluating the adenosine hypothesis of restless legs syndrome and its implications for current and future treatment strategies.

Size-Controlled Mesoporous Silica Nanoparticles via Template Nanoarchitectonics from a Deferoxamine Derivative for Enhanced Blood-Brain Barrier Permeability and Neuroprotective Chelation Therapy.

Advancing Iron Therapy in Maternal Health: Evolving Strategies for Treating Iron Deficiency Anemia.

TPX2 promotes ferroptosis in LPS-induced C28/I2 chondrocytes via NF-κB p65-mediated downregulation of GPX4 and SLC7A11.

Iron overload induces hepatic iron deposition and oxidative damage in freshwater fish Megalobrama amblycephala by inhibiting ferroportin 1 gene expression.

Parkinsonism in people with virally suppressed HIV.

ZIP14 upregulation leads to ferroptosis and lysosomal dysfunction through intracellular iron overload and induces myocardial ischemia/reperfusion injury in mouse hearts.

Dietary Iron Deficiency in Adult Mice Increases Brain Uptake of High-Affinity, Anti-Transferrin Receptor Antibody RI7217.

CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons.

Iron deficiency impact on exercise performance in patients with heart failure.

Integrated transcriptomics and proteomics reveal ferroptosis induced by B[a]P and BPDE in mouse hippocampal neurons.

Activation of GSDME by all-trans-retinal increases sensitivity to photoreceptor ferroptosis.

Melatonin inhibits liver ferroptosis in copper-laden rats: a potential therapy mechanism underlying Wilson's disease.

Gut microbiome restoring biogenic ferritin mineral as an effective oral iron supplement for iron deficiency anemia.

[The role of dietary aluminum exposure in disturbances of micronutrient metabolism and expression of metal transporter genes].

HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis.

Ferredoxins: master regulators in mitochondrial redox homeostasis and programmed cell death.

PIEZO1 gain-of-function mutation drives cardiomyopathy by disrupting myocardial lipid homeostasis besides iron overload.

Excess aldosterone and cortisol promote myocardial iron deficiency: A potential pathway to cardiac injury.

A homology-based 3D model and structure-function studies reveal key elements for divalent metal ion transporter ZIP8 (SLC39A8) function.

The Role of Iron as a Micronutrient in Key Biological Functions, Health and Diseases in Human.

Iron Deficiency in Drosophila melanogaster Glial Cells Impacts Behavior Through Altered Mitochondrial Dynamics.

KCNK3 coordinates adipocyte lipid storage and thermogenic shifts via AMPK, modulating a ferroptosis-permissive state.

Single-cell transcriptional decoding of iron deficiency responses in maize root tips.

Iron-Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders.

Cadmium induces ferroptosis in B cells via ATP6V0A1-upregulated lysosomal ferritinophagy: insights from murine transcriptomics and human cellular models.

Gnetol targeting of TNFAIP3 promotes SLC7A11 ubiquitination and ferroptosis in osteoclasts to ameliorate osteoporosis.

A Case of CACNA1I-Related Neurodevelopmental Disorder With Dysmorphism and Brain Iron Accumulation: Expanding the Clinical Spectrum.

The Volatile Pentadecane From Bacillus Alleviates Plant Iron Deficiency Through Activating the Reduction-Based Fe Uptake System.

Carnosic acid alleviated periodontitis by inhibiting ferroptosis via the Nrf2/GPX4 pathway.

Early pathological changes in the liver and kidney of non-obese diabetic (NOD) mice: involvement of iron accumulation and ferroptosis.

Multilayered epigenetic regulation of iron homeostasis in plants: From chromatin remodeling to genome engineering.

A structural deletion in the 3'UTR of SLC11A2 is associated with altered iron status: Evidence from two large Danish cohorts.

Interplay between mTORC1 signaling and iron homeostasis in muscle atrophy.

[Mechanism of Tougu Xiaotong Capsules regulating Malat1 and mi R-16-5p ceRNA to alleviate "cholesterol-iron" metabolism disorder in osteoarthritis chondrocytes].

Transcriptomic and proteomic profiling of Actinobacillus pleuropneumoniae responses to iron starvation.

Maternal iron deficiency alters the expression of glucose transporters in offspring.

Total favonoids of Desmodium Styracifolium relieve renal ischemia-reperfusion injury by suppressing ferroptosis through P53/SLC7A11/GPX4 signaling pathway.

Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early-Onset Parkinsonism.

ATF3 enhancement of CHAC1 expression: A pathway to neuronal ferroptosis in spinal cord injury.

Precision Phototherapy Enabled by Decoding Complex Microenvironments.

Iron: More than Meets the Eye.

Unraveling the Mystery of Hemoglobin in Hypoxia-Accelerated Neurodegenerative Diseases.

α-lipoic acid attenuates duodenal non-heme iron absorption via microRNA-mediated regulation of divalent metal transporter 1 in iron overloaded rats.

Indoor Dust Increases the Risk of Iron-Loading Anemia in Mice through Exogenous Iron-Induced Ineffective Erythropoiesis.

Cholesterol and 24S-OHC Induce Neuronal Apoptosis and Necroptosis, but Not Ferroptosis Despite Elevated Iron Levels.

BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states.

The role and mechanism of ERalpha(ERα) in atrazine-induced disorders of hepatic iron metabolism.

Intestinal hepcidin overexpression promotes iron deficiency anemia and counteracts iron overload via DMT1 downregulation.

Molecular insights into the role of ferroptosis in cardiorenal cross-talk: Mechanisms and future directions.

Iron Overload Accelerates Aging-Associated Kidney Injury in Mice: Implications for Iron Supplementation in the Elderly.

Ferroptosis-Resistant Adipocytes Drive Keloid Pathogenesis via GPX4-Mediated Adipocyte-Mesenchymal Transition and Iron-Cystine Metabolic Communication.

Unravelling the complex interplay between zinc, iron and their synergistic effect on LCPUFA metabolism in preeclampsia.

SGLT2 inhibitor therapy and lower incidence of iron deficiency anaemia in patients with type 2 diabetes: A retrospective cohort study from Germany.

Exploring the effects of maternal anemia on neonatal neurodevelopment: a systematic review and meta-analysis.

Deep Gray Matter Iron Deposition in NMOSD and MOGAD: A Comparative Study with MS.

A novel application of LC-MS/MS accurately quantifies the labile redox pools of cellular coenzymes Q9 and Q10.

Cadmium Inhibits Proliferation of Human Bronchial Epithelial BEAS-2B Cells Through Inducing Ferroptosis via Targeted Regulation of the Nrf2/SLC7A11/GPX4 Pathway.

Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.

Influence of plant-derived bioactive compounds on iron metabolism: mechanistic insights with translational relevance.

TRPM8 modulation alters uptake of Transferrin-mediated Fe3+, mitochondrial Fe2+ and intracellular Ca2+-levels in microglia.

CB2 and TRPV1 receptors in inflammatory state of macrophages from sickle cell anemia pediatric/young adults.

Effect of Self-Assembled Polydopamine Nanoparticles on Ferroptosis in an MPTP-Induced Parkinson's Disease Mice Model.

The cytochrome oxidase defect in ISC-depleted yeast is caused by impaired iron-sulfur cluster maturation of the mitoribosome assembly factor Rsm22.

An Analysis of AMPK and Ferroptosis in Cancer: A Potential Regulatory Axis.

Sitosterolemia carrying both ABCG5 and HBA gene mutations: a case report and review of the literature.

The presence of a H. pylori infection blunted the upregulation of iron-related duodenal proteins in response to anemia.

Dimethyl malonate preserves brain and neurobehavioral phenotype following neonatal hypoxia-ischemia by inhibiting FTH1-mediated ferritinophagy.

3D printing combined with pH-induced 4D printed iron(III)-oxidized starch gels for controlled iron delivery and enhanced iron supplementation.

SLC39A13 Regulates Heart Function via Mitochondrial Iron Homeostasis Maintenance.

Iron-Immune Crosstalk at the Maternal-Fetal Interface: Emerging Mechanisms in the Pathogenesis of Preeclampsia.

TORC2 and MAPK signaling pathways regulate mitochondrial degradation induced by iron starvation in Schizosaccharomyces pombe.

PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.

Nanozyme-synbiotics to improve iron-deficiency anemia.

Air pollution decreases postsynaptic PSD-95 and NMDA receptor subunits in synaptosomes from mouse cerebral cortex.

Prevalence of Restless Leg Syndrome and Its Association With Iron Deficiency in Patients With Chronic Kidney Disease: A Cross-Sectional Observational Study.

Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.

Fe-deficiency-induced chlorosis 1 is essential for chloroplast iron transport and homeostasis under continuous light conditions in Arabidopsis.

SGLT2 inhibitors and their influence on iron metabolism in the context of inflammation.

The Relationship Between Non-Transferrin-Bound Iron (NTBI), Labile Plasma Iron (LPI), and Iron Toxicity.

Dietary Heme Iron: A Review of Efficacy, Safety and Tolerability.

Vitamin K2 reprograms the multi-organ transcriptional landscape in mice with high-fat diet-induced obesity.

PIEZO2 is the underlying mediator for precise magnetic stimulation of PVN to improve autism-like behavior in mice.

Current Landscape of Hepcidin Therapeutics.

Iron Metabolism in Cardiovascular Disease.

Iron, Hepcidin, and Immunity.

Diagnosis and Management of Non-HFE Hemochromatosis, Ferroportin Disease, and Rare Hereditary Iron-Loading Disorders.

Systemic Iron Metabolism.

Rust and redemption: iron-sulfur clusters and oxygen in human disease and health.

A novel TIMM8A mutation in Mohr-Tranebjaerg syndrome without hearing loss and with basal ganglia iron deposition.

Herbacetin alleviates ferroptosis via Hif-1α/SLC7A11/GPX4 axis in traumatic brain injury.

Mechanisms of micro- and nanoplastics on blood-brain barrier crossing and neurotoxicity: Current evidence and future perspectives.

Molecular pathologies and therapies for Pelizaeus-Merzbacher disease.

Implementation of guidelines for intravenous iron therapy in heart failure patients.

Update of the sideroflexin (SLC56) gene family.

Paeoniflorin mitigates iron overload-induced osteoarthritis by suppressing chondrocyte ferroptosis via the p53/SLC7A11/GPX4 pathway.

[Hereditary haemochromatosis due to hepcidin resistance].

[A case of type 4A familial hereditary hemochromatosis].

Iron retention coupled with trade-offs in localized symbiotic effects confers tolerance to combined iron deficiency and drought in soybean.

Ferric-Chelate Reductase FRO3 Is Involved in Iron Homeostasis in Table Grape and Enhanced Plant Tolerance to Iron-Deficient Conditions.

3D-QSAR based computational screening of potent ligands against L-type calcium channel (LTCC) protein structure for iron overload in β-thalassemia.

Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.

Iron homeostasis and health: understanding its role beyond blood health - a narrative review.

Development of rat and mouse models of heme-iron absorption.

Clinical Outcomes of Intravenous Iron Therapy in Systolic Heart Failure Patients Receiving SGLT2 Inhibitors.

Calcium-iron crosstalk in epileptogenesis: Unraveling mechanisms and therapeutic opportunities.

Iron metabolism disorder and artesunate inhibiting tumor growth by inducing ferroptosis in Lymphangioleiomyomatosis.

Interfering with AQP1 alleviates ferroptosis, improves mitochondrial function and energy metabolic disorder in hypoxia/reoxygenation-induced H9c2 cardiomyocytes via Wnt/β-catenin pathway.

Iron Replacement Attenuates Hypoxic Pulmonary Hypertension by Remodeling Energy Metabolism via Regulating the HIF2α/Mitochondrial Complex I, III/ROS Axis.

Glucose deprivation-restoration induces labile iron overload and ferroptosis in renal tubules through V-ATPase-mTOR axis-mediated ferritinophagy and iron release by TPC2.

A Salmonella subset exploits erythrophagocytosis to subvert SLC11A1-imposed iron deprivation.

Abnormal Brain Iron Metabolism is Linked to Altered Neural Function in Isolated Laryngeal Dystonia.

Cisd1 synergizes with Cisd2 to modulate protein processing by maintaining mitochondrial and ER homeostasis.

Iron Metabolism and the Role of Iron Therapy in Pediatric Restless Leg Syndrome.

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

Uncovering a Novel Pathogenic Mechanism of BCS1L in Mitochondrial Disorders: Insights from Functional Studies on the c.38A>G Variant.

Cadmium exposure and its role in joint disease: A brief review of experimental and population-based evidence.

Unraveling the Serum Protein Landscape in Celiac Disease: Current Evidence and Future Directions.

Iron Deficiency Anemia Linked to Severe Pediculosis Capitis in a 12-Year-Old Boy.

Consensus of Expert Opinion for the Diagnosis and Management of Hypermanganesaemia With Dystonia 1 and 2.

miR-4478 Promotes Ferroptosis of Nucleus Pulposus Cells through Targeting SLC7A11 to Induce IVDD.

Astragenol alleviates neuroinflammation and improves Parkinson's symptoms through amino acid metabolism pathway and inhibition of ferroptosis.

Glutathione Decreases Parkinsonism-Induced Ferroptosis and Oxidative Stress Through the Inhibition of the TRPM2 Channel in Neuronal Cells.

The roles and mechanisms of CDGSH iron-sulfur domain 1 in kainic acid-induced mitochondrial iron overload, dysfunction and neuronal damage.

Delayed Upper Gastrointestinal Motility in Mice Treated with Oral Iron Tablets.

Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease.

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice.

Evidence of Oxytosis/Ferroptosis in Niemann-Pick Disease Type C.

Reactive astrocyte-derived exosomes enhance intracranial lymphatic drainage in mice after intracranial hemorrhage.

Genome-wide identification and analysis of the apple H+-ATPase gene family and its expression against iron deficiency stress.

Critical Importance of Iron Saturation in Lactoferrin: Effects on Biological Activity, Nutritional Functions, and Applications.

Targeting mitochondria-regulated ferroptosis: A new frontier in Parkinson's disease therapy.

A computational study of the fold and stability of cytochrome c with implications for disease.

Abnormal iron metabolism in the zona incerta in Parkinson's disease mice.

Women with Symptoms Suggestive of ADHD Are More Likely to Report Symptoms of Iron Deficiency and Heavy Menstrual Bleeding.

Characterization of the Priestia megaterium ZS-3 siderophore and studies on its growth-promoting effects.

Hypermagnesemia with Dystonia Type 2: Case Report of a New SLC30A10 Variant.

The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.

Eupatilin mitigates ICH-induced brain injury via SOX2/SLC7A11 regulation of ferroptosis.

Anemia Management in the Cardiorenal Patient: A Nephrological Perspective.

Studies of Slc30a10 Deficiency in Mice Reveal That Intestinal Iron Transporters Dmt1 and Ferroportin Transport Manganese.

Elesclomol rescues mitochondrial copper deficiency in disease models without triggering cuproptosis.

Iron Overload-Related Oxidative Stress Leads to Hyperphosphorylation and Altered Anion Exchanger 1 (Band 3) Function in Erythrocytes from Subjects with β-Thalassemia Minor.

Transcriptome and metabolome analysis reveal the mechanisms of iron absorption differences in apple rootstocks under alkaline condition.

Iron-Deficiency Anemia Elevates Risk of Diabetic Kidney Disease in Type 2 Diabetes Mellitus.

Involvement of iron ions in 6-hydroxydopamine-induced disruption of intracellular copper metabolism.

Neonatal sevoflurane exposures inhibits DHHC5-mediated palmitoylation of TfR1 in oligodendrocytes, leading to hypomyelination and neurological impairments.

Key role of the CSE/transsulfuration pathway in macrophage phenotypic change under iron overload.

Neurochemical alterations in the cerebellum of Friedreich's Ataxia mouse models.

Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis.

Mechanisms Underlying Iron Deficiency-Induced Cardiac Disorders: Implications for Treatment.

m6A Demethylase FTO-Mediated Upregulation of BAP1 Induces Neuronal Ferroptosis via the p53/SLC7A11 Axis in the MPP+/MPTP-Induced Parkinson's Disease Model.

Mechanism and regulation of iron absorption throughout the life cycle.

Peripheral blood immune cells from individuals with Parkinson's disease or inflammatory bowel disease share deficits in iron storage and transport that are modulated by non-steroidal anti-inflammatory drugs.

The Roles of DMT1 in Inflammatory and Degenerative Diseases.

The Neural Palette of Heme: Altered Heme Homeostasis Underlies Defective Neurotransmission, Increased Oxidative Stress, and Disease Pathogenesis.

Cell-free hemoglobin released from hemolysis induces programmed cell death through iron overload and oxidative stress in grass carp (Ctenopharyngodon idella).

Iron in the migraine brain.

Neurovascular unit impairment in iron deficiency anemia.

Iron deficiency promotes intra-leaflet hemorrhage-induced aortic valve calcification: an experimental study.

PRKAA2 Promotes Tumor Growth and Inhibits Ferroptosis through SLC7A11/GSH/GPX4 Pathway in Non-Small Cell Lung Cancer.

Therapeutic potential of 5-aminolevulinic acid in metabolic disorders: Current insights and future directions.

The Role of Trace Elements in COPD: Pathogenetic Mechanisms and Therapeutic Potential of Zinc, Iron, Magnesium, Selenium, Manganese, Copper, and Calcium.

Hepcidin as a therapeutic target in iron overload.

Macrophage P2Y12 regulates iron transport and its inhibition protects against atherosclerosis.