Odevixibat treatment for recurrent cholestasis in a patient with biallelic UNC45A variants causing osteo-oto-hepato-enteric syndrome.

Characterizing the frequency of clinical events and assessing biomarkers in propionic acidemia: a natural history study.

Linear Growth in Children With Cystic Fibrosis in the Netherlands Born Between 1997-2004; Results of a Multicenter Cohort Analysis.

TFR2 p.A75V mutation aggravates liver iron overload in alcoholic liver disease via ERK pathway.

Maternal Adiposity and DNA Methylation of TfR2 and HJV Genes in Early Pregnancy: Mediating Role of Inflammation and Consequences for Iron Status.

Back to basics: Bile acids in fat absorption.

Matriptase-2-mediated suppression of hepatic hepcidin expression in mice requires hepatocyte neogenin.

Computational analysis and molecular dynamics insights into deleterious SNPs of the HFE gene.

Inhibitory Potency of a Plant-Based Zinc Protoporphyrin on Heme Oxygenase Activity.

Estimation of New Regulators of Iron Metabolism in Short-Term Follow-Up After Bariatric Surgery.

Barth syndrome: Natural history in infants and young children.

SLC39A14 is Required for Iron Loading of the Anterior Pituitary of Mice with Genetic Iron Overload.

Molecular Pathogenesis of Joint Hypermobility: The Role of Intergenic Interactions.

The Hemojuvelin-Hepcidin Axis as a Target for the Treatment of Anemia or Conversely Polycythemia.

Ileal bile acid transporter inhibitors in Alagille syndrome and Progressive Familial Intrahepatic Cholestasis: A systematic review into dose-response.

Hereditary Hemochromatosis Type 2A Presenting With Hypogonadism, Diabetes, and Osteoporosis in a Young Woman.

Hemochromatosis Proteins Hemojuvelin and Homeostatic Iron Regulator in Bone Morphogenetic Protein-Mediated Hepcidin Regulation and Iron Homeostasis.

Diagnosis and Management of Non-HFE Hemochromatosis, Ferroportin Disease, and Rare Hereditary Iron-Loading Disorders.

Case report of hemochromatosis with HJV variation in a Chinese boy: "Non-parallel" phenomenon in phlebotomy treatment and new thinking on curative effect evaluation.

A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans.

Hemochromatosis and Hepatic Complications: A Comprehensive Review of Molecular Mechanisms, Diagnostics, and Emerging Therapeutics.

Iron overload is not the same everywhere: Particularities of iron-metabolism gene mutations in Brazil and a proposal for the investigation and management of iron overload in this population.

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

Assessment of HJV and SMN1 gene expression levels in infertile men: laboratory and bioinformatic approaches.

The Loss of HJV Aggravates Muscle Atrophy by Promoting the Activation of the TβRII/Smad3 Pathway.

Antibiofilm Activities of Tritrpticin Analogs Against Pathogenic Pseudomonas aeruginosa PA01 Strains.

[A case of type 2A juvenile hereditary hemochromatosis].

Iron overload in hereditary spherocytosis: Are genetic factors the cause?

[Analysis of clinical, gene mutation characteristics, and treatment prognosis of type 2A hereditary hemochromatosis in the Chinese population].

Bone phenotyping of murine hemochromatosis models with deficiencies of Hjv, Alk2, or Alk3: The influence of sex and the bone compartment.

Hepcidin expression is associated with increased γ-secretase-mediated cleavage of neogenin in the liver.

Juvenile Hemochromatosis Connecting Cardiac Arrest and Hypogonadotropic Hypogonadism in a Young Woman.

Influence of supplementation with probiotic bacteria Lactiplantibacillus plantarum and Latilactobacillus curvatus on selected parameters of duodenum iron metabolism in rats on a high-fat, iron-deficient diet.

Comparison of Diffusion-Weighted MRI Using Single-Shot Echo-Planar Imaging and Split Acquisition of Fast Spin-Echo Signal Imaging, a Non-EPI Technique, in Tumors of the Head and Neck.

Bile from the hemojuvelin-deficient mouse model of iron excess is enriched in iron and ferritin.

Insights into Iron Metabolism Parameters in Ischemic Stroke: A Single-Center Prospective Cohort Study.

The Genetic Diagnostics of Hemochromatosis: Disparities in Low- Versus High-Income Countries.

Process Evaluation of a Work Stress Prevention Approach in Primary Education: Exploring the Added Value of Real-Time Feedback During Implementation.

Hereditary haemochromatosis: Prevalence and characterization of the disease in a tertiary hospital in Aragon, Spain.

Novel compound heterozygous mutations in the hemojuvelin gene in a juvenile hemochromatosis patient: A case report.

Shifting Views on Cancer Pain Management: A Systematic Review and Network Meta-Analysis.

Hjv-/- mice in either C57BL/6 or AKR genetic background do not develop spontaneous liver fibrosis.

Investigation of BMP6 mutations in Brazilian patients with iron overload.

Efficacy and safety of odevixibat in patients with Alagille syndrome (ASSERT): a phase 3, double-blind, randomised, placebo-controlled trial.

Hemojuvelin-mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3.

First-in-Human Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of DISC-0974, an Anti-Hemojuvelin Antibody, in Healthy Participants.

HJV mutations causing hemochromatosis: variable phenotypic expression in a pair of twins.

A Review of New Concepts in Iron Overload.

The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity.

Times Are Changing: Why Quantitative Myocardial Perfusion Is to Be Preferred Over Qualitative Myocardial Perfusion.

Transmembrane serine protease 6, a novel target for inhibition of neuronal tumor growth.

Circulating microRNAs and hepcidin as predictors of iron homeostasis and anemia among school children: a biochemical and cross-sectional survey analysis.

Haemochromatosis in children: A national retrospective cohort promoted by the A.I.E.O.P. (Associazione Italiana Emato-Oncologia Pediatrica) study group.

Catastrophic health expenditure during the COVID-19 pandemic in five countries: a time-series analysis.

Characterization of fifteen key genes involved in iron metabolism and their responses to dietary iron sources in yellow catfish Pelteobagrus fulvidraco.

Myopathy and Ophthalmologic Abnormalities in Association With Multiple Skeletal Muscle Mitochondrial DNA Deletions.

FGF21 and GDF15 are elevated in Barth Syndrome and are correlated to important clinical measures.

Bioinformatics Analysis of the Genetic and Epigenetic Alterations of Bone Morphogenetic Protein Receptors in Metastatic Breast Cancer.

Added Predictive Value of Female-Specific Factors and Psychosocial Factors for the Risk of Stroke in Women Under 50.

Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis.

Primary Non-HFE Hemochromatosis: A Review.

Mass Balance and Absorption, Distribution, Metabolism, and Excretion Properties of Balcinrenone following Oral Administration in Combination with Intravenous Microtracer in Healthy Subjects.

Hereditary hemochromatosis: An update vision of the laboratory diagnosis.

Whole blood transfusion in the treatment of acute hemorrhage, a systematic review and meta-analysis.

Genetic Variations of ferroportin-1(FPN1-8CG), TMPRSS6 (rs855791) and Hemojuvelin (I222N and G320V) Among a Cohort of Egyptian β-Thalassemia Major Patients.

Cardiac Hamp mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron.

A Successful Living Donor Liver Transplantation Using Hepatic Iron Deposition Graft Suspected by Magnetic Resonance Imaging.

Managing the Dual Nature of Iron to Preserve Health.

An aberration correction approach for single and dual aperture ultrasound imaging of the abdomen.

The effectiveness of Foley catheter balloon tamponade versus expanding sponges and hemostatic granules for catastrophic penetrating groin hemorrhage with small skin defect: A comparative study in a live tissue porcine model with evaluation of a concise training program.

Evaluating associations between level of trauma care and outcomes of patients with specific severe injuries: A systematic review and meta-analysis.

Longitudinal relationship between albuminuria in infancy and childhood.

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice.

Application of Accelerator Mass Spectrometry to Characterize the Mass Balance Recovery and Disposition of AZD4831, a Novel Myeloperoxidase Inhibitor, following Administration of an Oral Radiolabeled Microtracer Dose in Humans.

Novel homozygote variant in the HJV gene leading to juvenile hemochromatosis: a case report.

Haemochromatosis revisited.

Machine learning for the prediction of acute kidney injury in patients after cardiac surgery.

A crosstalk between hepcidin and IRE/IRP pathways controls ferroportin expression and determines serum iron levels in mice.

Natural history comparison study to assess the efficacy of elamipretide in patients with Barth syndrome.

Radiation and immune checkpoint inhibitor-mediated pneumonitis risk stratification in patients with locally advanced non-small cell lung cancer: role of functional lung radiomics?

Surgical stabilization of rib fractures versus nonoperative treatment in patients with multiple rib fractures following cardiopulmonary resuscitation: An international, retrospective matched case-control study.

Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial.

Metabolomics in pediatric lower respiratory tract infections and sepsis: a literature review.

Effect of Cyclic Heat Stress on Hypothalamic Oxygen Homeostasis and Inflammatory State in the Jungle Fowl and Three Broiler-Based Research Lines.

Goat Milk Based Infant Formula in Newborns: A Double-Blind Randomized Controlled Trial on Growth and Safety.

Quality of Life and Quality of Death Outcomes of the SILENCE Study.

Juvenile Hemochromatosis due to a Homozygous Variant in the HJV Gene.

Hepcidin is potential regulator for renin activity.

Comparison of Two Automated Targeted Metabolomics Programs to Manual Profiling by an Experienced Spectroscopist for 1H-NMR Spectra.

Effects of Peri-Conception and Pregnancy Glycemic Variability on Pregnancy and Perinatal Complications in Type 1 Diabetes: A Pilot Study.

Hepcidin in hepatocellular carcinoma.

Estimates of West African Ancestry in African Americans Using Alleles of Iron-Related Genes HJV, SLC40A1, and TFR2.

Hemojuvelin deficiency promotes liver mitochondrial dysfunction and predisposes mice to hepatocellular carcinoma.

New Mutations in HFE2 and TFR2 Genes Causing Non HFE-Related Hereditary Hemochromatosis.

Identification of Novel Mutations by Targeted NGS Panel in Patients with Hyperferritinemia.

The feasibility and reliability of frailty assessment tools applicable in acute in-hospital trauma patients: A systematic review.

Correlation of genotype and phenotype in 32 patients with hereditary hemochromatosis in China.

Tissue-Specific Regulation of Ferroportin in Wild-Type and Hjv-/- Mice Following Dietary Iron Manipulations.

Chest wall injuries due to cardiopulmonary resuscitation and the effect on in-hospital outcomes in survivors of out-of-hospital cardiac arrest.

Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins.

Hepcidin-regulating iron metabolism genes and pancreatic ductal adenocarcinoma: a pathway analysis of genome-wide association studies.

Platelet to erythrocyte transfusion ratio and mortality in massively transfused trauma patients. A systematic review and meta-analysis.

Reliability of Quantitative 18F-FDG PET/CT Imaging Biomarkers for Classifying Early Response to Chemoradiotherapy in Patients With Locally Advanced Non-Small Cell Lung Cancer.

Combined heart-liver transplantation in a case of haemochromatosis.

SLN124, a GalNac-siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron-overload in a mouse model of β-thalassaemia.

Juvenile haemochromatosis.

Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice.

Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mask Mice.

Iron chelators reverse organ damage in type 4B hereditary hemochromatosis: Case reports.

Co-occurrence of vertebral artery hypoplasia and high jugular bulb in patients undergoing cranial magnetic resonance imaging.

Juvenile Hemochromatosis: Rheumatic Manifestations of 2 Sisters Responding to Deferasirox Treatment. A Case Series and Literature Review.

[A case of ferroportin disease with phenotype A gene mutation in SCL40A1 resembling phenotype B manifestation influenced by alcohol consumption].

A high-fructose diet in rats induces systemic iron deficiency and hepatic iron overload by an inflammation mechanism.

Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.

Outcome after surgical stabilization of rib fractures versus nonoperative treatment in patients with multiple rib fractures and moderate to severe traumatic brain injury (CWIS-TBI).

The association between level of trauma care and clinical outcome measures: A systematic review and meta-analysis.

Effects of an early life diet containing large phospholipid-coated lipid globules on hepatic lipid metabolism in mice.

Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.

Primary haemochromatosis resulting in dilated cardiomyopathy arising out of mutation in HJV gene in Indian patients: a rare scenario.

The Proteomics Study of Compounded HFE/TF/TfR2/HJV Genetic Variations in a Thai Family with Iron Overload, Chronic Anemia, and Motor Neuron Disorder.

Juvenile Hemochromatosis: A Case Report and Review of the Literature.

HFE inhibits type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation.

[Progress on epigenetic regulation of iron homeostasis].

Bone morphogenic proteins in iron homeostasis.

Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.

[Iron metabolism and iron-refractory iron deficiency anemia].

Evaluation of the level of selected iron-related proteins/receptors in the liver of rats during separate/combined vanadium and magnesium administration.

The Action of JAK/STAT3 and BMP/HJV/SMAD Signaling Pathways on Hepcidin Suppression by Tucum-do-Cerrado in a Normal and Iron-Enriched Diets.

The ectodomain of matriptase-2 plays an important nonproteolytic role in suppressing hepcidin expression in mice.

Novel Mutation in the Hemojuvelin Gene (HJV) in a Patient with Juvenile Hemochromatosis Presenting with Insulin-dependent Diabetes Mellitus, Secondary Hypothyroidism and Hypogonadism.

Immunosuppressant-Induced Oxidative Stress and Iron: A Paradigm Shift from Systemic to Intrahepatic Abnormalities.

Hemochromatosis in India: First Report of Whole Exome Sequencing With Review of the Literature.

Clinicopathological diagnosis and treatment of juvenile hemochromatosis.

Loneliness and Life Satisfaction Explained by Public-Space Use and Mobility Patterns.

Mutations and polymorphisms associated with iron overload in a series of 91 non-HFE haemochromatosis patients.

Parents' Perceptions of Infant Crying: A Possible Path to Preventing Abusive Head Trauma.

Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes.

Impact of Melatonin and Branched-Chain Amino Acids Cosupplementation on Quality of Life, Fatigue, and Nutritional Status in Cachectic Heart Failure Patients: A Randomized Controlled Trial.

Identification of heterozygous p.Y150C and p.V274M mutations in the HJV gene in a Japanese patient with a mild phenotype of juvenile hemochromatosis: A case report.

Mouse models of hereditary hemochromatosis do not develop early liver fibrosis in response to a high fat diet.

The functional role of hemojuvelin in acute ischemic stroke.

Genotypic and phenotypic spectra of hemojuvelin mutations in primary hemochromatosis patients: a systematic review.

Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium: Results of the REDUCE Study.

[Analysis of HFE and Non-HFE Mutations in a Tibet Cohort with Iron Overload].

Recent progress on inhibitors of the type II transmembrane serine proteases, hepsin, matriptase and matriptase-2.

High-Frame-Rate Echo-Particle Image Velocimetry Can Measure the High-Velocity Diastolic Flow Patterns.

Transfusion of pathogen-reduced platelet components without leukoreduction.

Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age-related muscle wasting.

Hepcidin and the BMP-SMAD pathway: An unexpected liaison.

Variation in the repulsive guidance molecule family in human populations.

Effect of atorvastatin on iron metabolism regulation in patients with chronic kidney disease - a randomized double blind crossover study.

Juvenile hemochromatosis with multi-organ involvement diagnosed at autopsy.

A novel SLC40A1 p.Y333H mutation with gain of function of ferroportin: A recurrent cause of haemochromatosis in China.

Inherited Disorders of Iron Overload.

Variable expressivity of HJV related hemochromatosis: "Juvenile" hemochromatosis?

Variable workup calls for guideline development for type 2A hereditary haemochromatosis.

Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.

Adult onset hereditary hemochromatosis is associated with a novel recurrent Hemojuvelin (HJV) gene mutation in north Indians.

MC-LR induces dysregulation of iron homeostasis by inhibiting hepcidin expression: A preliminary study.

Non-HFE mutations in haemochromatosis in China: combination of heterozygous mutations involving HJV signal peptide variants.

An Ex Vivo Fermentation Screening Platform to Study Drug Metabolism by Human Gut Microbiota.

Mitochondrial uncoupling prodrug improves tissue sparing, cognitive outcome, and mitochondrial bioenergetics after traumatic brain injury in male mice.

Phrenic neuropathy and diaphragm dysfunction in neuralgic amyotrophy.

High-Frame-Rate Contrast-enhanced US Particle Image Velocimetry in the Abdominal Aorta: First Human Results.

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite.

An In Vivo Study on Intoxicating Effects of Nerium oleander Water Based Extract on Multiorgans of Wistar Rat.

Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects.

A severe hemojuvelin mutation leading to late onset of HFE2-hemochromatosis.

Neuroimaging Findings of Organic Acidemias and Aminoacidopathies.

Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease.

Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery.

Matriptase-2 deficiency protects from obesity by modulating iron homeostasis.

Computer simulation of syringomyelia in dogs.

Transcriptome analysis reveals TMPRSS6 isoforms with distinct functionalities.

Identification of Genes for Hereditary Hemochromatosis.

Hemojuvelin Predicts Acute Kidney Injury and Poor Outcomes Following Cardiac Surgery.

Reversal of end-stage heart failure in juvenile hemochromatosis with iron chelation therapy: a case report.

A quantitative multimodal metabolomic assay for colorectal cancer.

Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy.

Causes of iron overload in blood donors - a clinical study.

Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.

Microvascular Permeability after an Acute and Chronic Salt Load in Healthy Subjects: A Randomized Open-label Crossover Intervention Study.

The mechanisms of systemic iron homeostasis and etiology, diagnosis, and treatment of hereditary hemochromatosis.

HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-Overload Murine Models.

Ferroportin disease: pathogenesis, diagnosis and treatment.

Effect of erythropoietin administration on proteins participating in iron homeostasis in Tmprss6-mutated mask mice.

Deletion of BMP6 worsens the phenotype of HJV-deficient mice and attenuates hepcidin levels reached after LPS challenge.

Prediction of work resumption and sustainability up to 1 year after mild traumatic brain injury.

[Progress in iron metabolism research].

"Haemochromatotic" characteristics of the human BEL-7402 cell line.

Serpinb3 is overexpressed in the liver in presence of iron overload.

Matriptase-2 suppresses hepcidin expression by cleaving multiple components of the hepcidin induction pathway.

A single-nucleotide polymorphism in transferrin is associated with soluble transferrin receptor in Chinese adolescents.

Angiogenic Markers Predict Pregnancy Complications and Prolongation in Preeclampsia: Continuous Versus Cutoff Values.

Deciphering the molecular basis of ferroportin resistance to hepcidin: Structure/function analysis of rare SLC40A1 missense mutations found in suspected hemochromatosis type 4 patients.

Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice.

A new form of IRIDA due to combined heterozygous mutations of TMPRSS6 and ACVR1A encoding the BMP receptor ALK2.

Synergistic inhibitory effects of deferasirox in combination with decitabine on leukemia cell lines SKM-1, THP-1, and K-562.