Exploring GHBP as a surrogate of GH activity in multimorbid older adults: A cross-sectional study.

Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1.

Near-Adult Height Outcomes in Patients Treated With rhIGF-1 for Severe Growth Failure: Real-World IGFD Registry Data.

IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution.

The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.

Characterization of Primary IGF-1 Deficiency in a Cohort of Canadian Children with Short Stature Using a Novel Algorithm Tailored to Electronic Medical Records.

Common and Uncommon Mouse Models of Growth Hormone Deficiency.

Evolving growth hormone deficiency: proof of concept.

Normal or improved cardiovascular risk factors in IGF-I-deficient adults with growth hormone receptor deficiency.

Diagnosis and treatment of growth hormone deficiency in children on the ketogenic diet: A case series.

Challenges in the care of individuals with severe primary insulin-like growth factor-I deficiency (SPIGFD): an international, multi-stakeholder perspective.

Insulin-Like Growth Factor 1 Receptor Deficiency Alleviates Angiotensin II-Induced Cardiac Fibrosis Through the Protein Kinase B/Extracellular Signal-Regulated Kinase/Nuclear Factor-κB Pathway.

Circulating insulin-like growth factor-1 and brain health: Evidence from 369,711 participants in the UK Biobank.

Recombinant Human Insulin-Like Growth Factor-1 Treatment of Severe Growth Failure in Three Siblings with STAT5B Deficiency.

Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance.

Congenital IGF-1 deficiency protects from cancer: lessons from Laron syndrome.

Short stature related to Growth Hormone Insensitivity (GHI) in childhood.

IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome.

The History of the Insulin-Like Growth Factor System.

Alterations in Stem Cell Populations in IGF-1 Deficient Pediatric Patients Subjected to Mecasermin (Increlex) Treatment.

Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish.

Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults.

Pubertal Timing and Growth Dynamics in Children With Severe Primary IGF-1 Deficiency: Results From the European Increlex® Growth Forum Database Registry.

Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mouse placentas.

DeepGP: An Integrated Deep Learning Method for Endocrine Disease Gene Prediction Using Omics Data.

Regulation of GH and GH Signaling by Nutrients.

Differential Diagnosis of the Short IGF-I-Deficient Child with Apparently Normal Growth Hormone Secretion.

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation.

Hepatic Igf1-Deficiency Protects Against Atherosclerosis in Female Mice.

Effectiveness and safety of rhIGF1 therapy in patients with or without Laron syndrome.

GH/IGF-1 Abnormalities and Muscle Impairment: From Basic Research to Clinical Practice.

IGF-I/IGFBP3/ALS Deficiency in Sarcopenia: Low GHBP Suggests GH Resistance in a Subgroup of Geriatric Patients.

IGF-I deficiency and enhanced insulin sensitivity due to a mutated growth hormone receptor gene in humans.

Isolated growth hormone deficiency in a Chihuahua with a GH1 mutation.

IGF-1 Deficiency Rescue and Intracellular Calcium Blockade Improves Survival and Corresponding Mechanisms in a Mouse Model of Acute Kidney Injury.

Anabolic Hormones Deficiencies in Heart Failure With Preserved Ejection Fraction: Prevalence and Impact on Antioxidants Levels and Myocardial Dysfunction.

Changes in plasma amino acids metabolites, caused by long-term IGF-I deficiency, are reversed by IGF-I treatment - A pilot study.

Insulin-like Growth Factor 1 Supports a Pulmonary Niche that Promotes Type 3 Innate Lymphoid Cell Development in Newborn Lungs.

Therapy with recombinant human IGF-1 for children with primary insulin-like growth factor-I deficiency.

Elevated levels of IL-6 and IGFBP-1 predict low serum IGF-1 levels during continuous infusion of rhIGF-1/rhIGFBP-3 in extremely preterm infants.

Disparate Central and Peripheral Effects of Circulating IGF-1 Deficiency on Tissue Mitochondrial Function.

A homozygous mutation in the highly conserved Tyr60 of the mature IGF1 peptide broadens the spectrum of IGF1 deficiency.

Loss of insulin-like growth factor-1 signaling in astrocytes disrupts glutamate handling.

Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells.

Genome-Wide Profiling of Laron Syndrome Patients Identifies Novel Cancer Protection Pathways.

Serum Insulin-Like Growth Factor I Deficiency Associates to Alzheimer's Disease Co-Morbidities.

Apoptosis signal-regulating kinase (ASK1) and transcription factor tumor suppressor protein TP53 suppress rabbit ovarian granulosa cell functions.

The second to fourth digit ratio in patients with congenital IGF-1 Deficiency.

Neurotrophic Factors and Their Receptors Are Altered by the Mere Partial IGF-1 Deficiency.

IGF-1 deletion affects renal sympathetic nerve activity, left ventricular dysfunction, and renal function in DOCA-salt hypertensive mice.

IGF - Autism prevention/amelioration.

Treatment of severe primary IGF-1 deficiency using rhIGF-1 preparation - first three years of Polish experience.

Nonclassical GH Insensitivity: Characterization of Mild Abnormalities of GH Action.

Sequential measurements of IGF-I serum concentrations in adolescents with Laron syndrome treated with recombinant human IGF-I (rhIGF-I).

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging.

Body height in paediatric inflammatory bowel diseases: A structural equation model analysis.

Supplementation of Blackcurrant Anthocyanins Increased Cyclic Glycine-Proline in the Cerebrospinal Fluid of Parkinson Patients: Potential Treatment to Improve Insulin-Like Growth Factor-1 Function.

Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate.

Partial growth hormone insensitivity and dysregulatory immune disease associated with de novo germline activating STAT3 mutations.

IGF1 affects macrophage invasion and activation and TNF-α production in the sciatic nerves of female SOD1G93A mice.

Bone resorption deficiency affects tooth root development in RANKL mutant mice due to attenuated IGF-1 signaling in radicular odontoblasts.

Targeted Resequencing of Putative Growth-Related Genes Using Whole Exome Sequencing in Patients with Severe Primary IGF-I Deficiency.

Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins.

Macrophage-derived insulin-like growth factor-1 affects influenza vaccine efficacy through the regulation of immune cell homeostasis.

Occurrence of Cranial Neoplasms in Pediatric Patients with Noonan Syndrome Receiving Growth Hormone: Is Screening with Brain MRI prior to Initiation of Growth Hormone Indicated?

The single IGF-1 partial deficiency is responsible for mitochondrial dysfunction and is restored by IGF-1 replacement therapy.

IGF-I deficiency, longevity and cancer protection of patients with Laron syndrome.

Growth hormone treatment for growth hormone deficiency and idiopathic short stature: new guidelines shaped by the presence and absence of evidence.

Controversies in the risk of neoplasia in GH deficiency.

Experimental approach to IGF-1 therapy in CCl4-induced acute liver damage in healthy controls and mice with partial IGF-1 deficiency.

Fifty years on: New lessons from Laron syndrome.

Characterization of four Latin American families confirms previous findings and reveals novel features of acid-labile subunit deficiency.

Primary lymphocytic hypophysitis: Clinical characteristics and treatment of 50 cases in a single centre in China over 18 years.

Growth Hormone Treatment in Children With Prader-Willi Syndrome: Three Years of Longitudinal Data in Prepubertal Children and Adult Height Data From the KIGS Database.

Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype.

Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice.

Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency.

Clinical and molecular diagnosis of a cartilage-hair hypoplasia with IGF-1 deficiency.

Multiple hormone deficiency syndrome in heart failure with preserved ejection fraction.

A CHILD WITH LARON SYNDROME ASSOCIATED WITH VASCULITIS.

Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.

IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis.

Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice.

Autophagy resolves early retinal inflammation in Igf1-deficient mice.

The insulin-like growth factor I receptor regulates glucose transport by astrocytes.

Smooth Muscle Insulin-Like Growth Factor-1 Mediates Hypoxia-Induced Pulmonary Hypertension in Neonatal Mice.

Insulin-like growth factor type 1 deficiency in a Moroccan patient with de novo inverted duplication 9p24p12 and developmental delay: a case report.

Klotho and the Growth Hormone/Insulin-Like Growth Factor 1 Axis: Novel Insights into Complex Interactions.

Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth.

Differential effects of IGF-1 deficiency during the life span on structural and biomechanical properties in the tibia of aged mice.

Partial IGF-1 deficiency induces brain oxidative damage and edema, which are ameliorated by replacement therapy.

The Effect of Recombinant Growth Hormone Treatment in Children with Idiopathic Short Stature and Low Insulin-Like Growth Factor-1 Levels.

Considering GH replacement for GH-deficient adults with a previous history of cancer: a conundrum for the clinician.

STAT5B deficiency: Impacts on human growth and immunity.

The future of growth-promoting therapy.

Challenges in the Management of Short Stature.

Intrauterine Growth Retardation (IUGR) as a Novel Condition of Insulin-Like Growth Factor-1 (IGF-1) Deficiency.

MECHANISMS IN ENDOCRINOLOGY: Novel genetic causes of short stature.

Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.

Mechanisms Underlying Testicular Damage and Dysfunction in Mice With Partial IGF-1 Deficiency and the Effectiveness of IGF-1 Replacement Therapy.

IGF1 deficiency in newly diagnosed Graves' disease patients.

IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.

Degradation of extracellular chondroitin sulfate delays recovery of network activity after perturbation.

Improved growth velocity of a patient with Noonan-like syndrome with loose anagen hair (NS/LAH) without growth hormone deficiency by low-dose growth hormone therapy.

Desensitization to mecasermin in an insulin-like growth factor 1-deficient patient.

Secondary IGF-I deficiency as a prognostic factor of growth hormone (GH) therapy effectiveness in children with isolated, non-acquired GH deficiency.