Linfoma de Hodgkin

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT05675410

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and/or CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma

NCT05169515

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

NCT06150664

CAR T-cell Therapy in Patients With Renal Dysfunction

NCT05909059

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Cell & bioscience2026 Mar 18

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Publicações mais relevantes

Timeline de publicações

14.840 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 14.840

#1

Proteome-wide Mendelian randomization identifies protein associations and therapeutic targets for B-cell malignancy.

Blood neoplasia2026 May

Despite therapeutic advances in B-cell malignancies, many patients continue to experience relapse or refractory disease, highlighting an unmet need for novel drug targets. The high attrition rate of drug development programs, however, represents a productivity-limiting step. To prioritize candidate drug targets, we used Mendelian randomization to evaluate causal associations between 2923 circulating proteins and 6 B-cell malignancies (22 922 cases and 388 978 controls). We identified 27 protein-disease associations, including TNFSF13 (APRIL) and TNFRS13B (TACI) in multiple myeloma, CD40 in Hodgkin lymphoma, and FAS in chronic lymphocytic leukemia. All results are interactively accessible via our R/Shiny application (https://software.icr.ac.uk/app/mrcan). Integrating single-cell RNA sequencing from 183 355 hematolymphoid cells, Bayesian colocalization, and clinical trial evidence, we prioritized 23 proteins as candidate drug targets. This study demonstrates the potential of human genetics to guide therapeutic discovery for B-cell neoplasia.

#2

METTL3 stabilizes FASN mRNA by mediating m6A modification to promote malignant progression of diffuse large B-cell lymphoma.

Diffuse large B-cell lymphoma (DLBCL) is an aggressive subtype of non-Hodgkin lymphoma. Fatty acid synthase (FASN) is a key lipogenic enzyme implicated in tumor progression, but its regulation in DLBCL is poorly understood. The function of FASN in DLBCL was explored using database analysis, clinical sample analysis, and cellular phenotyping experiments. Candidate m6A sites on FASN mRNA were predicted using the SRAMP database. Bioinformatics analyses and experimental techniques were conducted to elucidate the role of methyltransferase-like 3 (METTL3) on cell phenotypes and its regulation of FASN. The findings were further confirmed in mice models and clinical sample analyses. FASN was highly expressed in DLBCL and positively correlated with poor prognosis. FASN knockdown inhibited the malignant phenotypes in DLBCL cells by suppressing the PI3K/AKT and MAPK/ERK signaling pathways, as well as promoting endoplasmic reticulum (ER) stress. The analysis of FASN mRNA revealed the presence of m6A modification sites, and a positive correlation was identified between METTL3 and FASN. The impact of METTL3 knockdown on the malignant phenotypes of DLBCL cells was consistent with the effects induced by FASN knockdown, whereas METTL3 overexpression reversed the effects of FASN knockdown. Mechanistically, METTL3 stabilized FASN expression by mediating m6A modification of FASN mRNA, thereby facilitating DLBCL progression. METTL3 stabilizes FASN expression through m6A modification, thereby facilitating the DLBCL progression by activating the PI3K/AKT and MAPK/ERK signaling pathways and inhibiting the ER stress response pathway. The METTL3/FASN axis represents a potential therapeutic target, especially in METTL3/FASN-high DLBCL subgroups.

#3

Clinical Manifestations of Primary CNS T-Cell Lymphoma: A Retrospective Study of Histopathologic, Molecular, and Neuroimaging Features.

Neurology2026 Apr 14

Primary CNS T-cell lymphoma (PCNSTL) is an extremely rare and aggressive form of non-Hodgkin lymphoma. Diagnosis is often challenging because of the nonspecific clinical presentation, which can lead to delays in treatment. This study aims to analyze the clinical, histopathologic, and neuroimaging characteristics of PCNSTL. In this retrospective, multicentric cohort study, histologically confirmed PCNSTL cases without evidence of systemic disease were selected from pathology databases at 3 academic neuro-oncology centers (University Hospital of Munich, University Hospital of Heidelberg, Massachusetts General Hospital in Boston) during the period from 2008 to 2024. Retrospective data, including demographics, histopathology, immunophenotyping, multimodal MRI, and PET imaging, treatment lines, and outcome data were extracted from medical records and analyzed. We evaluated 16 patients (11 male) with a median age of 50 years (19-76 years) and a median Karnofsky performance status of 80% (20%-100%). T-cell clonality was confirmed in 9/15 (60%) tested patients with typical T-cell receptor gene rearrangement patterns. MRI scans at primary diagnosis showed predominantly supratentorial parenchymal lesions with prominent contrast enhancement in 14/16 (87.5%) and in more than one-third multifocal lesions (7/16, 43.75%). High intratumoral susceptibility signal was frequently observed (7/16, 43.75%). [18F]fluorodeoxyglucose-PET and [18F]fluoroethyltyrosine-PET imaging revealed only low to moderate tracer uptake in 7/8 examined patients (87.5%). Median progression-free survival was 4 months, and median overall survival was 97.5 months. Although treatment protocols varied, the use of methotrexate (MTX)-based chemotherapy combined with autologous stem-cell transplant (ASCT) was associated with most favorable outcome (95% CI 2-87, p < 0.0275). In 1 case of ALK1-positive PCNSTL, persistent complete remission was achieved after treatment with the ALK-inhibitor lorlatinib. Although PCNSTL is exceptionally rare, we identified distinct neuroimaging patterns showing highly aggressive features on MRI but hypometabolic PET imaging, which may assist in identifying future PCNSTL cases. Despite the limited cohort size, our findings suggest that MTX-based chemotherapy with ASCT may translate into favorable outcome. We report on an ALK1-positive PCNSTL case with sustained complete remission after targeted therapy with lorlatinib.

#4

Association of MMP-2 and MMP-9 Polymorphisms and the Pathogenesis of Childhood Burkitt's Lymphoma.

Pediatric blood & cancer2026 Mar 15

Burkitt lymphoma (BL) is a highly aggressive and invasive non-Hodgkin lymphoma derived from germinal center B cells and represents one of the most common childhood malignancies. Matrix metalloproteinases (MMPs) play a critical role in cancer progression by remodeling the extracellular matrix and modulating the tumor microenvironment. In advanced stages, MMPs facilitate tumor invasion and metastasis through the degradation of extracellular matrix components. This study aimed to investigate the association between MMP-2 and MMP-9 gene polymorphisms and the pathogenesis of childhood BL. This study was conducted at the Pediatric Oncohematology Center of the University of Pernambuco between 2021 and 2023 and included patients of both sexes aged 1 to 18 years diagnosed with BL between 1993 and 2023. Genomic DNA was extracted from peripheral blood samples using the salting-out method. Polymorphisms were identified by real-time polymerase chain reaction (PCR) using the TaqMan system. A total of 56 patients diagnosed with BL were analyzed; most were male, with a mean age of 7.1 years. The overall survival rate was 92.6%. A protective effect of the mutant TT genotype was observed compared to the wild-type CC genotype (OR = 0.0562; 95% CI: 0.0068-0.4644; p = 0.0016) for the MMP-2 polymorphism. Furthermore, individuals carrying the mutant G allele showed a positive association with BL compared to the wild-type A allele (G vs. A: OR = 1.9920; 95% CI: 1.1812-3.3594; p = 0.0130). These findings contribute to a better understanding of the genetic factors influencing BL susceptibility and support the need for further functional and large-scale studies to elucidate the mechanistic role of MMP-2 and MMP-9 polymorphisms in BL pathogenesis.

#5

Real-World Outcomes of Allogeneic Stem Cell Transplantation in Relapsed Hodgkin Lymphoma: A Single-Center Experience from India.

Blood cell therapy2026 Feb 25

Relapsed Hodgkin lymphoma (HL) after autologous stem cell transplantation (auto-HSCT) remains a major therapeutic challenge with few curative options. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) may provide durable disease control, yet outcome data from tertiary-care centres in India are limited. To evaluate real-world outcomes of allo-HSCT in patients with chemotherapy-sensitive relapsed HL at a tertiary care centre in North India. This retrospective study included patients with chemotherapy-sensitive relapsed HL who underwent allo-HSCT at the Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, between January 2017 and December 2023. Clinical data including baseline characteristics, transplant parameters, complications, and survival outcomes were reviewed. Descriptive statistics were used, and overall survival (OS) was estimated using the Kaplan-Meier method. Five patients (median age 18 years; range 14-30) with chemotherapy-sensitive relapse following auto-HSCT underwent allogeneic transplantation in complete remission (CR) after salvage therapy. Donors included haploidentical (n=3), matched unrelated (n=1), and matched sibling (n=1). Four patients received reduced-intensity conditioning; one received myeloablative conditioning. Graft-versus-host disease (GVHD) prophylaxis included post-transplant cyclophosphamide (PT-Cy) in four patients. Neutrophil and platelet engraftment occurred at median 15 and 16 days, respectively. All patients developed bacterial infections; one succumbed to Gram-negative sepsis. Acute grade III GVHD occurred in one patient, and two developed limited chronic GVHD. At a median follow-up of 44 months, four patients remained in continuous remission, with a 3-year OS of 80%. In Indian patients with chemotherapy-sensitive relapsed HL, allo-HSCT using reduced-intensity and reduced toxicity conditioning regimens and post-transplant cyclophosphamide-based regimens has proven feasible and effective, yielding encouraging survival outcomes within routine clinical practice.

Publicações recentes

Diffuse Gastrointestinal Polyposis Revealing Mantle Cell Lymphoma: A Case Highlighting a Diagnostic Pitfall.

Cureus2026 Mar

Extranodal nasal-orbital communicating lesions NK/T cell lymphoma with ocular symptoms as the initial manifestation misdiagnosed as sinusitis and orbital cellulitis: a case report and literature review.

Front Oncol2026

Occult obstructive sleep apnea in survivors of Hodgkin lymphoma following radiation therapy: an atypical and under-recognized phenotype.

J Clin Sleep Med2026 Apr 16

Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial.

Int J Clin Oncol2026 Apr 16

Lenalidomide Plus Rituximab for Relapsed/Refractory Indolent Non-Hodgkin Lymphoma: 5-Year Follow-Up and Subgroup Analyses From the Phase III AUGMENT Trial.

J Clin Oncol2026 Apr 16

Ver todas no PubMed

📚 EuropePMC11.719 artigos no totalmostrando 199

Qualitative Study of Breast Cancer and Lymphoma Patients Participating in a Physical Activity Intervention: The Case for Tailored Physical Activity.

Cancer medicine

Clinicopathologic patterns and treatment outcomes of pediatric classic hodgkin lymphoma in Ethiopian newly opened cancer treatment centers.

BMC pediatrics

European journal of nuclear medicine and molecular imaging

The predictive and prognostic role of baseline 2-[18F]FDG PET/CT volumetric and dissemination features in classical Hodgkin lymphoma.

Paraneoplastic Hepatitis Associated with Relapsed Nodular Lymphocyte-Predominant Hodgkin Lymphoma.

Hematology reports

European journal of nuclear medicine and molecular imaging

A convolutional neural network for fully automated total metabolic tumor volume delineation in patients with aggressive Non-Hodgkin lymphoma.

European journal of dermatology : EJD

A case of secondary papuloerythroderma of Ofuji associated with classic Hodgkin lymphoma.

Choosing between Nivo-AVD and BrECADD: Hodgkin lymphoma's new era.

Prognostic impact of monocyte percentage and extranodal involvement in classical hodgkin lymphoma: A multicenter real-world study of 547 chinese patients.

A case of pulmonary mucosa-associated lymphoid tissue lymphoma with plasmacytic differentiation and amyloid deposition: case report and literature review.

Allogeneic hematopoietic stem cell transplantation following T-cell-directed immunotherapy failure in B-cell lymphoma: a real-world case series and systematic literature review.

Evaluating functional hyposplenism in pediatric hodgkin lymphoma: the role of marginal zone b cells post-radiotherapy.

BMC cancer

Predictors and timing of venous thromboembolism and overall survival in lymphoma.

Proteome-wide Mendelian randomization identifies protein associations and therapeutic targets for B-cell malignancy.

Blood neoplasia

A global multidimensional analysis of the chimeric antigen receptor T-cell therapy clinical trial landscape and development trends.

Biomarker research

Development and validation of the ultrasound-based radiomics and deep learning prognostic models for diffuse large B-cell lymphoma.

Prognostic value of interim PET-CT in follicular lymphoma.

Medicina clinica

Real-World Evidence for Pembrolizumab Gemcitabine Vinorelbine and Liposomal Doxorubicin in Classical Hodgkin Lymphoma.

Blood advances

HOD08 for low-risk pediatric Hodgkin lymphoma.

Blood

Advances in laboratory medicine

Pericardial fluid cytology as a diagnostic tool for diffuse large B-cell lymphoma: a case report.

Hodgkin Variant Richter's Transformation in the Absence of Classical Risk Factors: A Rare Case With Spinal Manifestation.

Novel immunotherapeutic strategies for diffuse large B-cell lymphoma: a comprehensive review.

Frontiers in immunology

METTL3 stabilizes FASN mRNA by mediating m6A modification to promote malignant progression of diffuse large B-cell lymphoma.

Cell & bioscience

Sarcopenia and sarcopenic obesity after chemotherapy in childhood lymphoma.

JCO clinical cancer informatics

Building Capacity for Research on Cancer, Older Adults, and Under-Represented Populations: Methods and Lessons Learned From the Development of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center-Medicare Database.

Lipegfilgrastim for primary prophylaxis of febrile neutropenia in patients treated for advanced-stage classical hodgkin lymphoma: successful outcomes from a multicenter cohort study.

The American Journal of dermatopathology

Pilomatrix Carcinoma in a Hodgkin Lymphoma Survivor: A Rare Second Primary Tumor.

Veterinary and comparative oncology

Generation of a Rabbit Anti-Canine CD19 Monoclonal Antibody From Peripheral Blood and Its Validation in Immunoassays and CAR-T Feasibility.

Primary extranodal marginal zone non-hodgkin lymphoma of the prostate: a case report.

Zhongguo shi yan xue ye xue za zhi

[Research Progress in ALK+/- Anaplastic Large Cell Lymphoma--Review].

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

APDS in a 3-year-old boy presenting with EBV viremia and hodgkin lymphoma associated with a novel germline heterozygous variant in PIK3CD and with characteristic immune phenotype but no upregulation of the T cell mTOR pathway.

Mediastinal grey zone lymphomas: Results of the expert pathological review analysis of a case series enrolled in the multicentre BIOGZL-2020 study in Italy.

Clinical Manifestations of Primary CNS T-Cell Lymphoma: A Retrospective Study of Histopathologic, Molecular, and Neuroimaging Features.

Neurology

TET2 germline mutation in a patient with sequential lymphoid malignancies: a novel case report.

American journal of hematology

Zanubrutinib in AL Amyloidosis Associated With Waldenström Macroglobulinemia and Other B-Cell Non-Hodgkin Lymphoma.

International journal of surgery case reports

Diffuse large B-cell lymphoma as a rare cause of small bowel obstruction: case report and literature review.

Case Report: Isolated acetabular myeloid sarcoma as the initial presentation of extramedullary blast crisis in chronic myeloid leukemia: a report of two cases and literature review.

Cost-utility Analysis of R-CHOP vs CHOP in Patients with Non-Hodgkin's Lymphoma: A Systematic Review.

Acta medica Philippina

Pediatric Ileocecal Burkitt Lymphoma Presenting as a Diagnostic Challenge After a Nondiagnostic Surgical Biopsy: A Case Report.

Advanced pharmaceutical bulletin

GAS5 Long Noncoding RNA Regulates CD20 Expression and Rituximab Response.

Association of MMP-2 and MMP-9 Polymorphisms and the Pathogenesis of Childhood Burkitt's Lymphoma.

Pediatric blood & cancer

Cancer control : journal of the Moffitt Cancer Center

Five-Year Survival and Determinants of Diffuse Large B-cell Lymphoma in Resource-Limited Settings: The Impact of HIV/AIDS in a Multi-Center Cohort Study.

Prognostic Value of the CALLY Index in Diffuse Large B-Cell Lymphoma: Linking Inflammation, Nutrition, and Tumor Biology.

Focus on Extremely Late Relapses in Hodgkin Lymphoma: A Single Center Analysis.

Tumor Mutational Burden as a Prognostic Biomarker in Follicular Lymphoma.

Journal of clinical medicine

Clinical Significance of MTHFR C677T and A1298C Polymorphisms in Adult Patients with ALL and NHL.

The American journal of clinical nutrition

Dietary fat consumption and cancer outcomes: An umbrella review of systematic reviews and meta-analyses.

Metachronous multiple primary cancers involving pulmonary non-Hodgkin lymphoma and bladder cancer: a case report.

Extranodal Marginal Zone B-cell Lymphoma Presenting as a Painless Buccal Mass in the Masticator Space.

Journal of medical cases

Comparative pathogenesis and management of orbital/conjunctival and gastric MALT lymphoma: Microbial drivers, molecular mechanisms, and therapeutic implications.

Survey of ophthalmology

Immunoprofiling, sex- and age-related determinants of treatment response in paediatric, adolescent and young adult Hodgkin lymphoma.

International journal of laboratory hematology

Joint Assessment of CD38, CD138, and Immunoglobulin Light Chains Supports the Differential Diagnosis Between Classical Hodgkin Lymphoma and Plasmablastic Lymphoma.

Systematic echocardiogram surveillance to early detect and treat doxorubicin hydrochloride-induced cardiomyopathy in young adults and adults with classical Hodgkin lymphoma. Comment on: Long-term cardiac morbidity in adolescent and young adult survivors of classical Hodgkin lymphoma: the British Columbia experience.

To B or not to B, that is the question: the role of bleomycin in early stage Hodgkin lymphoma.

Mind the gap: anti-PD-1 salvage before autologous transplantation in classical Hodgkin lymphoma.

Systemic metastatic retinal lymphoma masquerading as granulomatous uveitis.

GMS ophthalmology cases

A novel prognostic model integrating host vulnerability and tumor biology for elderly patients with diffuse large B-cell lymphoma: the BAMAL score.

Real-World Outcomes of Allogeneic Stem Cell Transplantation in Relapsed Hodgkin Lymphoma: A Single-Center Experience from India.

Blood cell therapy

Pooled safety analysis of zanubrutinib monotherapy in Asian patients with B-cell malignancies.

ESMO open

Journal of immunology research

CD47 Expression in Classic Hodgkin Lymphoma and Its Association With Tumor Microenvironment.

Risk of Cancer in Patients with Hidradenitis Suppurativa: A Systematic Review and Meta-analysis.

Dermatology and therapy

Expert opinion on investigational drugs

Targeting the CD47/SIRPα interaction in cancer: opportunities in non-Hodgkin lymphoma.

Journal of medical economics

Economic value of lost productivity attributable to premature cancer mortality and morbidity across Europe.

Burden of Middle-Aged and Elderly Patients With Non-Hodgkin Lymphoma From 1990 to 2021: A Systematic Analysis Based on the Global Burden of Disease 2021.

Cancer medicine

An Uncommon Result in a Common Finding: The Rare Case of a Gastric Glomus Tumor.

ACG case reports journal

Molecular therapy. Oncology

Outcomes of point-of-care manufactured CAR T cell therapy for B cell acute lymphoblastic leukemia and non-Hodgkin lymphoma in Vietnam.

International journal of particle therapy

Long Term Results of Proton Therapy in Adult Infradiaphragmatic Lymphoma.

Family history of haematological malignancy and prognosis across non-Hodgkin lymphoma subtypes.

Incidence of severe COVID-19 in patients with chronic lymphocytic leukaemia or indolent B-cell non-Hodgkin lymphoma who received vaccination and pre-exposure prophylaxis with tixagevimab and cilgavimab in Italy: An observational study by the GIMEMA working party on chronic lymphoproliferative disorders and by the Fondazione Italiana Linfomi.

Transplant infectious disease : an official journal of the Transplantation Society

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023-2024 Outbreak in Argentina.

Expert review of hematology

"Per aspera ad astra": the transformative contribution of glucarpidase to the improved management of delayed methotrexate elimination after high-dose therapy.

Flaccid Lower Limb Paraparesis Despite Infiltration of the Spinal Cord by a Secondary Central Nervous System T-cell Non-Hodgkin Lymphoma With Syringomyelia: A Case Report.

American journal of hematology

Five-Year Follow-Up: Tandem CD19/CD20 CAR T Therapy Enduring Impact on Refractory/Relapsed Non-Hodgkin Lymphoma.

The American journal of surgical pathology

Comprehensive Assessment of CD19 Immunohistochemical Staining in Classic Hodgkin Lymphoma.

Bibliometric analysis of global hodgkin lymphoma research from 2002 to 2022.

Discover oncology

Bone marrow transplantation

Bispecific antibodies followed by allogeneic hematopoietic stem cell transplantation as rescue therapy in refractory/relapsed B cell non-Hodgkin lymphoma: a real-life experience.

Low-grade B-cell non-Hodgkin lymphoma in the sternocleidomastoid muscle: a case report and review of literature.

Therapeutic advances in medical oncology

Fotemustine-containing chemotherapy suggests lower toxicity with comparable efficacy versus high-dose methotrexate-based regimens: a retrospective cohort analysis.

Put the CAR-T before the HRS: Advances in Anti-CD30 Immunotherapy Targeting Hodgkin/Reed-Sternberg Cells in Classical Hodgkin Lymphoma.

Oncology research

The European CAR-T map-Current status and future directions to improve access to CAR T-cell therapy for hematologic malignancies.

HemaSphere

Renal dysfunction in symptomatic Waldenström macroglobulinaemia: A nationwide Italian multicentre study.

Population health metrics

Reframing disease burden: validation of DALY-per-case as a per-diagnosis severity metric.

Cancer treatment and research communications

Preliminary evaluation of Chidamide in combination with novel [177Lu]Lu-DOTAGA-rituximab in rituximab-resistant Raji cells.

Epstein-Barr virus-associated lymphoma: current understanding and treatment strategies.

Blood research

Journal of cancer survivorship : research and practice

Hospitalization for medical conditions in adolescent and young adult cancer survivors: a nationwide cohort study using the Netherlands Cancer Registry.

Exome sequencing of Hodgkin and non-Hodgkin composite lymphomas identifies shared somatic mutations indicative of common founding precursors.

Cancer genetics

HIV-associated lymphoproliferative disorders: Single-center experience.

Medicine

Evolution of outcomes in autologous stem cell transplantation for hodgkin lymphoma over 2 decades at King Hussein cancer center.

Understanding hairy cell leukemia in the context of mature B-cell neoplasms: tumor microenvironment and extracellular vesicle contribution to disease pathogenesis.

Frontiers in immunology

Case report and literature review: Golidocitinib as a potential treatment for monomorphic epitheliotropic intestinal T-cell lymphoma.

From genetic variants to therapeutic targets: A study reveals MMS19 and HLA genes in Hodgkin lymphoma pathogenesis.

Cancer chemotherapy and pharmacology

BET inhibitor OPN-2853 in advanced solid tumors and lymphoma: results from the phase 1b PLX124-01 trial.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Validation of an AI Method for Automated Lymphoma Metabolic Tumor Volume Segmentation Using a Public Benchmark PET/CT Dataset.

Critical reviews in oncology/hematology

Efficacy of zanubrutinib in diffuse large B-cell lymphoma: A single-arm meta-analysis.

International journal of radiation oncology, biology, physics

Executive Summary of the American Radium Society Appropriate Use Criteria for Extranodal NK/T-Cell Lymphoma.

Pretransplant promise for PD-1 in Hodgkin lymphoma.

Blood

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Trends in Long-Term Excess Mortality Risk and Survival Among Childhood and Adolescent Cancer Survivors in the United States.

Bleomycin omission in limited-stage classic Hodgkin lymphoma with negative PET scan after two cycles of ABVD.

Case Report: Glofitamab in the treatment of a patient with central nervous system-involved Burkitt lymphoma.

Science or hype? A cross-sectional analysis of the quality of Hodgkin lymphoma-related short videos.

Digital health

Haploidentical allogeneic hematopoietic stem cell transplantation in relapsed/refractory Hodgkin lymphoma in the era of novel agents: a single-center experience.

Peripheral T-cell lymphoma-NOS presenting with cavitary lung lesions mimicking invasive aspergillosis.

BMJ case reports

Richter transformation to classical Hodgkin lymphoma following recurrent disseminated histoplasmosis in chronic lymphocytic leukemia: a Case Report.

Multilesional pyoderma gangrenosum secondary to Hodgkin lymphoma.

JAAD case reports

Primary Breast Lymphoma in Mexico: A 15-Year Retrospective Case Series From a Tertiary Center Suggesting a Distinctly Early Age at Presentation.

Indian journal of pediatrics

Assessing the Impact of Rituximab on Treatment Outcomes in Pediatric Advanced Mature B-Non Hodgkin Lymphoma.

Real-world clinical effectiveness of trimethoprim-sulfamethoxazole for primary prophylaxis of pneumocystis pneumonia in non-hodgkin lymphoma patients treated with rituximab.

PloS one

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Understanding the factors influencing quality of life among survivors of Non-Hodgkin lymphoma after completing primary treatment: a systematic review.

Secondary primary malignancies in indolent non-Hodgkin lymphoma patients receiving frontline bendamustine-rituximab.

Cancer

Journal of hematopathology

A rare diffuse follicular lymphoma with TP53 mutation and copy-neutral loss of heterozygosity at 1p36: insights into diagnosis, disease progression, and literature review.

The International journal of biological markers

Causal association between oxidative stress and lymphomas: A two-sample Mendelian randomization study.

Journal of the National Comprehensive Cancer Network : JNCCN

Targeting BCMA in Plasmablastic Lymphoma With Teclistamab: A Case Study of Three Patients.

Immunopharmacology and immunotoxicology

Breviscapine inhibits the proliferation and immune escape of diffuse large B-cell lymphoma cells by regulating JAK2/STAT3/PD-L1 pathway.

Distribution and clinical significance of peripheral blood lymphocyte PD-1 and PD-L1 in non-Hodgkin lymphoma: a retrospective study in Chinese patients.

Primary Diffuse Large B-Cell Lymphoma Mimicking a Dental Abscess: A Case Report.

Clinical case reports

Journal of clinical neuromuscular disease

An Unusual Case of Anti-FGFR3 Antibodies, Sensory Neuropathy, and Adie Pupil in a Patient With Hodgkin Lymphoma in Remission and Review of the Literature.

Houttuynia cordata Thunb. Essential Oil Inhibits Diffuse Large B-cell lymphoma Growth.

Journal of oleo science

Practical radiation oncology

Management and Outcomes for Hodgkin's Lymphoma Patients with Partial Metabolic Response after First-Line Systemic Therapy.

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Real-world evaluation of health-related quality of life in hematology patients treated with rituximab: results of a multicentric cross-sectional cohort study.

Clinical lymphoma, myeloma & leukemia

Comparison of Outcomes With Novel Versus Traditional Chemotherapy Regimens for Relapsed and Refractory Classical Hodgkin Lymphoma.

Clinical journal of gastroenterology

Classic hodgkin lymphoma associated with Epstein-Barr virus reactivation during vedolizumab therapy for ulcerative colitis.

Self-reported late effects, daily functioning, and health-related quality of life in older Hodgkin lymphoma survivors - a national population-based cross-sectional survey.

[Updates on primary mediastinal large B-cell lymphoma and mediastinal gray zone lymphoma].

Annales de pathologie

Current research in translational medicine

Necrotic locally advanced nasal NK/T-cell lymphoma: the timely diagnostic challenge.

Clinical oncology (Royal College of Radiologists (Great Britain))

The National Non-Hodgkin Lymphoma Audit: Insights and Impact.

Efficacy of Standard-Dose Versus Low-Dose Nivolumab in Relapsed/Refractory Hodgkin Lymphoma-A Retrospective Analysis.

JCO global oncology

Future oncology (London, England)

Operational efficiencies of using one vs multiple bispecific antibodies for diffuse large B-cell lymphoma and follicular lymphoma in the US.

bioRxiv : the preprint server for biology

Neurometabolic correlates of accelerated aging and neurocognitive late effects in long-term survivors of pediatric hodgkin lymphoma and acute lymphoblastic leukemia.

International journal of particle therapy

Comparing Organs at Risk Sparing Between Intensity-Modulated Radiotherapy and Pencil-Beam Scanning Plans Based on Disease Location for Hodgkin and Non-Hodgkin Lymphoma.

Journal of clinical medicine

CT-Guided Lung Biopsy Using Dual-Energy Iodine Mapping to Target Lung Masses with Necrotic Tissue-A Proof-of-Concept Study.

Life (Basel, Switzerland)

Primary Adrenal Gland Lymphoma: Report of 13 Cases-A Retrospective Multicenter Polish Lymphoma Research Group Analysis.

Medicina (Kaunas, Lithuania)

Risk of Cancer in Patients with Rheumatoid Arthritis Compared with the General Population: A Nationwide Cohort Study in Lithuania.

Medicina (Kaunas, Lithuania)

Prognostic Significance of the Systemic Inflammation Response Index (SIRI) in Patients with Hodgkin Lymphoma.

International journal of molecular sciences

Decoding NOTCH1: From T-Cell Development Guardian to Driver of Pediatric T-Cell Lymphoblastic Lymphoma.

Lipid Metabolism Reprogramming in Diffuse Large B-Cell Lymphoma (DLBCL): Mechanisms and Treatment Strategies.

Children (Basel, Switzerland)

Secondary Neoplasm in Survivors of Childhood Hematological Malignancies-Systematic Review.

British journal of cancer

Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continents.

Transplantation and cellular therapy

Association Between Patient-Reported Outcomes Prior to Chimeric Antigen Receptor (CAR) T-Cell Therapy and Clinical Outcomes.

Resolution of vanishing bile duct syndrome in a patient associated with refractory hodgkin lymphoma following Anti-PD-1 therapy: a case report and literature review.

Extranodal NK/T-Cell Lymphoma, Nasal Type, Presenting as an Isolated Oral Manifestation.

Dentistry journal

Immune-related adverse events in the treatment of Hodgkin lymphoma with immune checkpoint inhibitors.

Associations of serum lipid traits with DLBCL: a prospective cohort study from the UK Biobank.

Frontiers in nutrition

Characterization of JNJ-80948543 a novel CD79bxCD20xCD3 trispecific antibody for B-cell non-Hodgkin lymphoma.

Anti-programmed cell death protein 1-based salvage therapy for relapsed/refractory Hodgkin lymphoma: a multicenter real-world analysis.

Is it time to reduce the doxorubicin dosage in Hodgkin lymphoma therapy?

Giornale italiano di cardiologia (2006)

[Primary mediastinal B-cell lymphoma presenting as cardiac tamponade: the importance of a multimodality imaging approach].

Long-term Health Outcomes in Older Blood or Marrow Transplantation Recipients: A Report from the BMTSS.

Blood advances

The surgery for the patients with intestinal non‑Hodgkin lymphomas: a nationwide study.

Annals of medicine

Journal of investigative medicine high impact case reports

Unmasking Diffuse Large B-Cell Lymphoma: A Challenging Case of Acute Cardiac Tamponade in the Setting of Right-Sided Heart Mass Invasion.

A pharmacovigilance study of rituximab-associated adverse events in immune-mediated kidney diseases and transplant-related kidney diseases.

International journal of radiation biology

Demographic and clinical profiles of patients with primary and second primary cancers: identifying biomarkers of sensitivity to radiotherapy-induced cancer.

Geographical variation in Hodgkin lymphoma incidence patterns by histological subtype and sex: a population-based analysis of cancer registry data.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Characteristics and Outcomes of Patients with Hodgkin Lymphoma with Paraneoplastic Manifestations.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Expression of Programmed Death Ligand 1 (PD-L1) in Classical Hodgkin Lymphoma- Study from a Tertiary Care Cancer Centre in South India.

Research on the correlation and potential mechanism of PKCδ expression with efficacy and prognosis in diffuse large B-cell lymphoma.

Safety and clinical outcomes of a first-in-human trial of point-of-care manufactured trispecific CAR T cells targeting CD19, CD20, and CD22.

Research square

Pre-treatment endocrine-nutritional signatures predict clinical benefit from PD-1/PD-L1 blockade in hematologic malignancies.

Frontiers in nutrition

Digestive diseases and sciences

Infliximab Monotherapy Versus Infliximab and Azathioprine Combination Therapy in Patients with Ulcerative Colitis: A Cost-Effectiveness Analysis.

Machine learning based on clinical and gene expression data assists in survival prediction and treatment optimization for diffuse large B-Cell lymphoma patients.

Prognostic impact of treatment-related and geriatric factors in older patients with classic Hodgkin lymphoma: A real-life cohort study.

International journal of cancer

Patient- and caregiver-reported barriers to radiotherapy for cancer in sub-Saharan Africa-A survey of population-based registries.

Molecular biology reports

Genetic variations of STAT3 gene and their role in hodgkin lymphoma incidence.

Descriptive Case Series of Childhood Lymphomas Treated at the Children's Hospital of Mexico.

Pediatric reports

Primary Bone Lymphoma of the Jaw Masquerading as Infection and Delaying Treatment.

Hematology reports

Cladosporium cladosporioides Fungemia in a Patient with Non-Hodgkin Lymphoma: An Extremely Rare Case and Review of the Literature.

Reports (MDPI)

The burden of cancers and their variations across the states of US the global burden of disease study 1990-2021.

Journal of medical imaging and radiation sciences

The evolving role of [¹⁸F]FDG PET/CT in reducing or replacing biopsy in selected malignancies: A narrative literature review.

Primary Central Nervous System Lymphoma With Testicular and Prostatic Involvement: A Case Report.

Hematology/oncology clinics of North America

Early-Stage Hodgkin Lymphoma: Time for Novel Agents?

Hematology/oncology clinics of North America

Classic Hodgkin Lymphoma in the Older Adult: What's New?

International journal of laboratory hematology

An Unusual Case of Classic Hodgkin Lymphoma With Strong Expression of B-Cell Markers.

Potential of Exercise for Prevention of Cardiovascular Disease in Survivors of Childhood Hodgkin Lymphoma.

JACC. CardioOncology

Obstructive Jaundice Revealing Primary Diffuse Large B-Cell Lymphoma of the Ampulla of Vater in a Child: A Case Report.

Case reports in oncology

Efficacy of immune checkpoint inhibitors in paediatric, adolescent and young adults with primary refractory or relapsed classical Hodgkin lymphoma: A national multicentre real-world study.

Type 2 diabetes and risk of non-Hodgkin lymphoma and multiple myeloma: a pooled analysis.

JNCI cancer spectrum

Oncology (Williston Park, N.Y.)

2025 Report on the Mantle Cell Lymphoma Scientific Consortium and Workshop Hosted by the Lymphoma Research Foundation.

Second Primary Subglottic Laryngeal Carcinoma After Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone (CHOP) Chemotherapy for Non-Hodgkin Lymphoma.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Role of ¹⁸F-FDG PET Metabolic Parameters in Treatment Response Evaluation and Prognostic Assessment of Hodgkin Lymphoma: A Retrospective Analysis.

Journal of the National Comprehensive Cancer Network : JNCCN

Optimizing the Role of Checkpoint Inhibitors in the Management of Hodgkin Lymphoma.

Puzolcabtagene Autoleucel: Pediatric First Approval.

Paediatric drugs

Journal of oral and maxillofacial pathology : JOMFP

Challenges in delineating B-cell lymphoma: A case of plasmablastic lymphoma mimicking Burkitt lymphoma.

Clinical characteristics, treatment patterns, and survival in mantle cell lymphoma: a real-world cohort.

Laboratory investigation; a journal of technical methods and pathology

High-Resolution Spatial Transcriptomic Characterization of Syncytial Variant of Nodular Sclerosis Classical Hodgkin Lymphoma.

Clinical lymphoma, myeloma & leukemia

A Call for Compassion: How You Can Help Get Multiple Myeloma Added to the Social Security Administration's Compassionate Allowances List.

Journal of geriatric oncology

Individualized physical activity program for older adults undergoing chemotherapy for hematologic malignancies.

International journal of molecular sciences

Unlocking the Secrets of Regulated Cell Death in Large B-Cell Lymphoma Beyond Apoptosis: Signaling Pathways and Therapeutic Options.

Immune Checkpoint Blockade in Hematological Malignancies: Current Status and Future Directions.

Hodgkin Lymphoma-The Effect of Chemotherapy on Gonadal Function and Fertility Is Strongly Related to the Treatment Regimen, Age, and Sex: A Systematic Review and Meta-Analysis.

Signal transduction and targeted therapy

Long-term follow-up demonstrates the curative potential of dual CD19/CD22 CAR-T-cell therapy alone or combined with autologous stem cell transplantation in TP53-altered relapsed/refractory B-cell non-Hodgkin lymphoma.

Applied immunohistochemistry & molecular morphology : AIMM

Prognostic Impact of CD57⁺ Natural Killer Cells and CD138⁺ Plasma Cells as Minor Components of the Tumor Microenvironment in Mixed Cellularity Classical Hodgkin Lymphoma.

Hematology/oncology clinics of North America

The Modern Role of Radiation Therapy in Classic Hodgkin Lymphoma.

Follicular lymphoma transformed to classic Hodgkin lymphoma.

Blood

Global trends and inequities in childhood cancer burden from 1990 to 2021, with projections to 2040: a Global Burden of Disease study.

The predictive value of interleukin-2 receptor and prognostic nutritional index in patients with diffuse large B-cell lymphoma.

Frontiers in medicine

Saudi journal of medicine & medical sciences

Incidence of de novo Lymphoproliferative Disorders and Hematological Malignancies in Liver Transplant Recipients: An Updated Meta-Analysis.

Paraneoplastic reactive perforating collagenosis in setting of Hodgkin lymphoma and prior marginal zone lymphoma.

JAAD case reports

Disease burden of hematological malignancies worldwide, in China and in the United States based on the GLOBOCAN 2022 and Global Burden of Disease 2021 data.

Chinese medical journal

Journal of the National Comprehensive Cancer Network : JNCCN

Hodgkin Lymphoma, Version 1.2026, NCCN Clinical Practice Guidelines In Oncology.

Journal of the National Comprehensive Cancer Network : JNCCN

Evaluating Vulnerable Elders Survey-13 and FIL Geriatric Assessment in Older Adults With Aggressive Lymphomas.