Rationally engineered cyclodextrins: smart shuttles for neurological drug targeting and BBB modulation.

Structural transport and inhibition mechanism of the mitochondrial pyruvate carrier.

ADIPOQ regulates lipid metabolism by activating AMPK/CPT-1 pathway to attenuate the proliferation of psoriasis lesions.

Nanoscale conformational dynamics of human propionyl-CoA carboxylase.

A repurposed AMP binding domain reveals mitochondrial protein AMPylation as a regulator of cellular metabolism.

SIRT3 deficiency aggravates mitochondrial metabolic disorder and podocyte injury in DKD via MPC2 acetylation.

Update of the sideroflexin (SLC56) gene family.

LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension.

Glyceraldehyde-3-phosphate dehydrogenase/1,3-bisphosphoglycerate-NADH as key determinants in controlling human retinal endothelial cellular functions: Insights from glycolytic screening.

Current Understanding of Pathogenic Mechanisms and Disease Models of Citrin Deficiency.

Structure of human PINK1 at a mitochondrial TOM-VDAC array.

The Role of Solute Carrier Family Transporters in Hepatic Steatosis and Hepatic Fibrosis.

PINK1 controls RTN3L-mediated ER autophagy by regulating peripheral tubule junctions.

A hierarchical hepatic de novo lipogenesis substrate supply network utilizing pyruvate, acetate, and ketones.

Distinct roles for the domains of the mitochondrial aspartate/glutamate carrier citrin in organellar localization and substrate transport.

Metabolic cycles: A unifying concept for energy transfer in the heart.

Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import.

A pseudoautosomal glycosylation disorder prompts the revision of dolichol biosynthesis.

DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage.

A recurrent missense variant in the E3 ubiquitin ligase substrate recognition subunit FEM1B causes a rare syndromic neurodevelopmental disorder.

Identification of novel tail-anchored membrane proteins integrated by the bacterial twin-arginine translocase.

AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.

Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells.

Changes in Plasma Pyruvate and TCA Cycle Metabolites upon Increased Hepatic Fatty Acid Oxidation and Ketogenesis in Male Wistar Rats.

Ketone body β-hydroxybutyrate (BHB) preserves mitochondrial bioenergetics.

Brown fat thermogenesis and branched-chain amino acids in metabolic disease.

BDNF-loaded PDADMAC-heparin multilayers: a novel approach for neuroblastoma cell study.

A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei.

Aspartate-glutamate carrier 2 (citrin): a role in glucose and amino acid metabolism in the liver.

Mitochondrial protein import clogging as a mechanism of disease.

Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis.

Reverse and Forward Electron Flow-Induced H2O2 Formation Is Decreased in α-Ketoglutarate Dehydrogenase (α-KGDH) Subunit (E2 or E3) Heterozygote Knock Out Animals.

Lipoate protein ligase B primarily recognizes the C8-phosphopantetheine arm of its donor substrate and weakly binds the acyl carrier protein.

Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis.

Novel targets for ameliorating energy metabolism disorders in depression through stable isotope-resolved metabolomics.

Mechanistic insights into multiple-step transport of mitochondrial ADP/ATP carrier.

Glucocerebrosidase Mutations Cause Mitochondrial and Lysosomal Dysfunction in Parkinson's Disease: Pathogenesis and Therapeutic Implications.

Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.

Identification and characterization of novel MPC1 gene variants causing mitochondrial pyruvate carrier deficiency.

Mitochondrial H+ Leak and Thermogenesis.

Brain Atrophy and White Matter Damage Linked to Peripheral Bioenergetic Deficits in the Neurodegenerative Disease FXTAS.

Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes.

A novel remitting leukodystrophy associated with a variant in FBP2.

Mitochondrial Pyruvate Carrier Subunits Are Essential for Pyruvate-Driven Respiration, Infectivity, and Intracellular Replication of Trypanosoma cruzi.

Sequence Features of Mitochondrial Transporter Protein Families.

A Single Cysteine Residue in the Translocation Pathway of the Mitosomal ADP/ATP Carrier from Cryptosporidium parvum Confers a Broad Nucleotide Specificity.

The Discovery of Highly Potent THP Derivatives as OCTN2 Inhibitors: From Structure-Based Virtual Screening to In Vivo Biological Activity.

Aldehyde Dehydrogenase 2 Ameliorates Chronic Alcohol Consumption-Induced Atrial Fibrillation through Detoxification of 4-HNE.

Bioenergetic Impairment of Triethylene Glycol Dimethacrylate- (TEGDMA-) Treated Dental Pulp Stem Cells (DPSCs) and Isolated Brain Mitochondria are Amended by Redox Compound Methylene Blue †.

Mitochondrial Fatty Acids and Neurodegenerative Disorders.

Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review.

A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC.

Fatty Acid Oxidation and Mitochondrial Morphology Changes as Key Modulators of the Affinity for ADP in Rat Heart Mitochondria.

APOE alters glucose flux through central carbon pathways in astrocytes.

Mechanism of activation of the human cysteine desulfurase complex by frataxin.

Mitochondrial Carriers for Aspartate, Glutamate and Other Amino Acids: A Review.

A pyruvate dehydrogenase complex disorder hypothesis for bipolar disorder.

Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome.

Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy.

Emerging Roles in the Biogenesis of Cytochrome c Oxidase for Members of the Mitochondrial Carrier Family.

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier.

Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder.

Mutations of the mitochondrial carrier translocase channel subunit TIM22 cause early-onset mitochondrial myopathy.

Endothelial Mitochondrial Preprotein Translocase Tomm7-Rac1 Signaling Axis Dominates Cerebrovascular Network Homeostasis.

PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect.

Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.

Disulfide driven folding for a conditionally disordered protein.

De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.

Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, dolichol, ubiquinone and sterol synthesis.

Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases.

Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity.

CRISPR fixes disease gene in viable human embryos.

Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex.

Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle myotubes.

Treatable Inborn Errors of Metabolism Due to Membrane Vitamin Transporters Deficiency.

Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells.

Understanding the Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 1 (MMDS1)-Impact of a Disease-Causing Gly208Cys Substitution on Structure and Activity of NFU1 in the Fe/S Cluster Biosynthetic Pathway.

VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.

TIM29 is a subunit of the human carrier translocase required for protein transport.

Natural and Induced Mitochondrial Phosphate Carrier Loss: DIFFERENTIAL DEPENDENCE OF MITOCHONDRIAL METABOLISM AND DYNAMICS AND CELL SURVIVAL ON THE EXTENT OF DEPLETION.

Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number.

Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations.

Cereblon in health and disease.

Severe Neonatal Presentation of Mitochondrial Citrate Carrier (SLC25A1) Deficiency.

Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice.

The mitochondrial phosphate carrier: Role in oxidative metabolism, calcium handling and mitochondrial disease.

Fatal neonatal encephalopathy and lactic acidosis caused by a homozygous loss-of-function variant in COQ9.

Clinical and biochemical characterization of four patients with mutations in ECHS1.

The hyperornithinemia-hyperammonemia-homocitrullinuria syndrome.

Resveratrol reduces amyloid-beta (Aβ₁₋₄₂)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans.

Mitochondrial biology, targets, and drug delivery.

Mitochondrial pyruvate transport: a historical perspective and future research directions.