Raras
Buscar doenças, sintomas, genes...
Imunodeficiência adquirida
ORPHA:310050CID-10 · B2424.CID-11 · 4A20DOENÇA RARA

Síndrome da imunodeficiência adquirida é uma doença do sistema imunológico humano causada pelo vírus da imunodeficiência humana. Durante a infecção inicial, uma pessoa pode passar por um breve período doente, com sintomas semelhantes aos da gripe. Normalmente isto é seguido por um período prolongado sem qualquer outro sintoma. À medida que a doença progride, ela interfere mais e mais no sistema imunológico, tornando a pessoa muito mais propensa a ter outros tipos de doenças, como infecções oportunistas e câncer, que geralmente não afetam as pessoas com um sistema imunológico saudável.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

Síndrome rara de início adulto caracterizada por infecções recorrentes (respiratórias, urinárias), disfagia e dispneia. Apresenta bronquiectasias, fraqueza, baixos níveis de anticorpos e aplasia/hipoplasia do timo.

Publicações científicas
22.408 artigos
Último publicado: 2026
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: B2424.
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Entender a doença

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫁
Pulmão
4 sintomas
🩸
Sangue
4 sintomas
🫃
Digestivo
2 sintomas
💪
Músculos
1 sintomas
🫘
Rins
1 sintomas
👁️
Olhos
1 sintomas

+ 6 sintomas em outras categorias

Características mais comuns

Início na idade adulta
Disfagia
Dispneia
Bronquiectasia
Infecções respiratórias recorrentes
Fraqueza fatigável
21sintomas
Sem dados (21)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 21 características clínicas mais associadas, ordenadas por frequência.

Início na idade adultaAdult onset
DisfagiaDysphagia
DispneiaDyspnea
BronquiectasiaBronchiectasis
Infecções respiratórias recorrentesRecurrent respiratory infections

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico22.408PubMed
Últimos 10 anos200publicações
Pico2025100 papers
Linha do tempo
2026Hoje · 2026🧪 1981Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

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Genética e causas

O que está alterado no DNA e como passa nas famílias

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Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Imunodeficiência adquirida

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Selecione um estado ou use sua localização para ver resultados.

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Ensaios clínicos abertos e novidades científicas recentes

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Publicações mais relevantes

Timeline de publicações
3.486 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 3.486

#1

BCG Infection Following Therapy of Infant Acute Lymphoblastic Leukemia.

Pediatric blood & cancer2026 Mar 15

The Bacillus Calmette-Guérin (BCG) vaccine is widely administered in tuberculosis-endemic regions. BCG infection (BCGitis) is a rare vaccine adverse event seen in immunocompromised patients. While BCGitis is well documented in patients with inborn errors of immunity and acquired immunodeficiency, data on BCGitis in infants with hematological malignancies are scarce. We retrospectively analyzed five cases of BCGitis in infants with acute lymphoblastic leukemia (ALL) and treated at a single tertiary pediatric oncology center. Clinical characteristics, timing of BCGitis in relation to anticancer therapy, immune parameters, management, and outcomes were reviewed. The median age at ALL diagnosis was 1.5 months (range, 0.5-5.3); four patients had KMT2A rearrangements. All received BCG vaccination with the Russian BCG strain vaccine at birth. BCGitis developed during chemotherapy (n = 2), blinatumomab immunotherapy (n = 1), or post-hematopoietic stem cell transplantation (HSCT; n = 2). One patient with BCGitis during chemotherapy had a reactivation of BCGitis after HSCT. All cases presented as localized infection; one had regional lymphadenitis. BCGitis onset correlated with either T-cell reconstitution or therapy-induced cytopenia. Antimycobacterial therapy (levofloxacin, amikacin, isoniazid, and ethambutol) led to resolution in all cases. BCGitis in infants with acute leukemia is a rare complication that is likely associated with chemotherapy-induced immunodeficiency or immune reconstitution following chemotherapy, immunotherapy, or HSCT. While manifestations are typically localized, careful management is required to prevent further complications. This is particularly crucial for patients undergoing HSCT, where prophylactic antimycobacterial therapy may be considered in selected high-risk settings.

#2

Resilient in adversity: Innovative treatment support interventions in facilitating ART adherence among young adults living with HIV in the informal settlements of Kibera, Nairobi.

PloS one2026

Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) poses significant health challenges. Despite ongoing efforts to scale up Antiretroviral therapy (ART) to save lives from AIDS-related morbidity and mortality,adherence among young adults remains low at 65% in sub-Saharan Africa. Our study aimed to inform the development of youth-friendly, context-sensitive programs that are both scalable and sustainable in urban informal settlements. This paper presents findings on youth facilitators to ART adherence in Kibera informal settlement. The study was conducted in Nairobi urban informal settlement of Kibra, Nairobi county, Kenya. We utilized in-depth interviews (n = 25) and key informant interviews (n = 10) to collect data on faciliators to ART adherence among purposively selected eligible partcipants. Thematic analysis framework was employed to analyze the data. HIV adherence facilitators encompassed patient-related factors like self-acceptance and open disclosure, health system factors such as accessibility, provider relationships, and patient reminders, and socio-economic aspects including support groups, education awareness, family support, and economic empowerment. The findings emphasize the need for tailored, age-appropriate, and context-specific interventions in informal settlements to enhance HIV adherence. Fostering self-acceptance, creating an enabling environment through youth friendly services, improving provider-patient relationships, and leveraging social support systems such as peer groups and educational initiatives are essential strategies. Integrating these elements into programmatic and policy frameworks will ensure that interventions resonate with the unique realities of this populationpromoting sustainable adherence outcomes. The findings will provide a foundation for developing context-sensitive interventions and programs to improve adherence in similar settings.

#3

Delayed viral rebound post-ART interruption in infant macaques given SIV-specific neutralizing antibodies.

Cell reports. Medicine2026 Mar 17

Interventions to prevent HIV rebound in the absence of antiretroviral therapy (ART) are needed. Here, we use a rhesus macaque model of pediatric HIV to assess the impact of simian immunodeficiency virus (SIV) Env-specific rhesus monoclonal antibodies (RhmAbs) on viral rebound. We find that RhmAb-treated infants experience delayed rebound compared to controls (median of 64 versus 7.5 days, p = 0.0007). Time to rebound very strongly correlates with both ITS102.01-LS concentrations (r = 0.9, p = 0.002) and anti-drug antibodies against ITS103.01-LS (r = -0.95, p = 0.008). SIVgag-specific CD8+ T cell levels increase after RhmAb administration and negatively correlate with rebound viremia (r = -0.67, p = 0.0415). Treatment also expands neutralization breadth and potency against tier 2 and tier 3 viruses in 5/8 and 3/8 RhmAb-receiving animals, respectively. Thus, giving SIV Env RhmAbs prior to ART cessation leads to prolonged time to viral rebound, enhanced antiviral T cell responses, and broadening of neutralization capacity, thereby supporting use of neutralizing Abs to promote post-ART viral control.

#4

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

Science immunology2026 Feb 13

Broadly neutralizing antibodies (bNAbs) are rarely elicited during HIV-1 infection. To identify obstacles to bNAb development, we longitudinally studied 122 rhesus macaques infected by 1 of 16 different simian-human immunodeficiency viruses (SHIVs). We identified the V2 apex region of the envelope (Env) as the most common bNAb target and a subset of Envs that preferentially elicited these antibodies. In 10 macaques, we delineated Env-antibody coevolution from B cell priming to bNAb development. Antibody phylogenies revealed permissive developmental pathways guided by evolving Envs that contained few mutations in or near the V2 apex C-strand, which were a sensitive indicator of apex-targeted responses. The absence of such mutations reflected a failure in bNAb priming. These results indicate that efficiency of B cell priming, and not complexities in Env-guided affinity maturation, is a primary obstacle to V2 apex bNAb elicitation in SHIV-infected macaques and identify specific HIV-1 Envs to advance as vaccine platforms.

#5

Prevalence and predictors of virological failure and quality of life of people with HIV/AIDS at a Municipal Hospital, Volta Region -Ghana: A cross-sectional study.

PloS one2026

Despite several interventions to eradicate HIV/AIDS globally, virological failure continues to threaten the goals of antiretroviral therapies (ART) and quality of life (QoL) of people with HIV/AIDS (PWHA). This study aimed to assess the prevalence and predictors of virological failure and determine the QoL of PWHA. A cross-sectional study was conducted at the ART clinic of a Municipal Hospital, from June to August 2023, to assess the socio-demographic, medical data, and QoL of PWHA receiving therapy at the clinic. Participants were randomly selected and interviewed: their weight and height were taken and their clinic folders examined to assess virological failure status. Both self-developed structured questionnaire and the WHOQOL-HIV BREF scale (Cronbach alpha = 0.84) were used to assess participants' data. Bivariate and multiple logistic regression analysis were conducted to determine predictors of virological failure. Also, multiple linear regression was conducted to determine factors influencing QoL of study participants. A total of 398 participants comprising of 328 (82.41%) females, and with a mean age of 48.2 years (SD ± 11.71 years), were recruited into the study. The prevalence of virological failure was 6.03%. Factors such as forgetting to take ART (Adjusted Odds Ratio (AOR) = 2.87, 95% Confidence Interval (CI) = 1.02, 7.51; p = 0.04), being classified as baseline WHO clinical staging II (AOR = 6.20, 95% CI = 1.91, 20.04; p = 0.002), and HIV stigmatization (AOR = 3.97, 95% C.I. = 1.1, 14.25; p = 0.035) were associated with virological failure. The overall QoL was good (75.35%). Having no comorbidities (Coefficient of Determination (β) = -2.7, p < 0.0001), having social support (β = 3.94, p < 0.0001) and receiving an average monthly income (β = 2.03, p = 0.002) contributed to good QoL. Virological failure in the municipality exceeded the 5.0% target set by the Joint United Nations Programme, despite majority of the study participants presenting with good QoL. The National AIDS Control Programme should consider long-acting injectable therapy for PWHA struggling to adhere to medication.

Publicações recentes

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📚 EuropePMC6.087 artigos no totalmostrando 200

2025

Human Immunodeficiency Virus Misdiagnosis in a Patient Presenting with Clinical Features of AIDS in Malawi: A Case Report.

Malawi medical journal : the journal of Medical Association of Malawi
2026

Varicella-Zoster Virus Infection in an Immunocompromised Patient With Seizure-Like Activity and Septic Shock: A Case Report.

Cureus
2026

Pneumomediastinum and Subcutaneous Emphysema as Initial Presentations of Pneumocystis Jirovecii Pneumonia in a Newly Diagnosed HIV-Infected Patient: A Case Report.

Journal of acute medicine
2026

Extending t linear mixed models for longitudinal data with non-ignorable dropout applied to AIDS studies.

Biometrical journal. Biometrische Zeitschrift
2026

Argon laser demarcation of AIDS-related cytomegalovirus retinitis in resource-limited setting.

International ophthalmology
2026

Cryptococcus neoformans Meningitis in a Patient With Epidermolysis Bullosa and Rheumatoid Arthritis.

Cureus
2026

Case report: thoracic syphilitic gumma masquerading as a malignant tumor in a patient with AIDS.

AIDS research and therapy
2026

Study of retroviral restrictions in a Tadarida bat cell line enlightens specific early blocks and TRIM5 locus multiplication.

Journal of virology
2026

Smac mimetic combined with eCD4-Ig reverses latency without reducing SHIV reservoirs in rhesus macaques.

The Journal of clinical investigation
2026

Negative influence of age and low baseline CD4 on T helper cell recovery among HIV-infected individuals with fixed-dose combination of tenofovir disoproxil, lamivudine and dolutegravir.

Frontiers in public health
2026

BCG Infection Following Therapy of Infant Acute Lymphoblastic Leukemia.

Pediatric blood &amp; cancer
2026

Towards Ending HIV/AIDS by 2030: Trajectory of Sub-Saharan Africa-A Post-COVID-19 (2019-2024) Review.

Reviews in medical virology
2025

Bibliometrics of scientific biomedical publications on Primary Immunodeficiency Diseases in the Arab World (2020-2024).

La Tunisie medicale
2026

Disseminated Mycobacterium tilburgii infection complicated by pulmonary non-tuberculosis mycobacteriosis in a patient with acquired immunodeficiency syndrome: A case report and literature review.

Medicine
2026

Disseminated iatrogenic upper gastrointestinal Kaposi sarcoma following prolonged steroid use in a patients with Crohn's disease: a case report.

Journal of medical case reports
2026

Patients living with HIV in the modern era: Postoperative outcomes and healthcare utilization.

American journal of surgery
2026

Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis.

Journal of affective disorders
2026

Acquired Immunodeficiency in Newborn Following Intrauterine Exposure to Thiopurines for Treatment of Inflammatory Bowel Disease.

ACG case reports journal
2026

Clinical Pharmacology Quality Assurance Program for Global HIV and Co-Infection Drug Development.

Clinical pharmacology and therapeutics
2026

Resilient in adversity: Innovative treatment support interventions in facilitating ART adherence among young adults living with HIV in the informal settlements of Kibera, Nairobi.

PloS one
2026

Providers' Perspectives on the Social Determinants of Health and Burnout Among HIV Care Providers in the United States.

Cureus
2026

Declining prevalence of AIDS-defining illness among newly diagnosed people living with HIV in northern Thailand: a 10-year review.

BMC infectious diseases
2026

Delayed viral rebound post-ART interruption in infant macaques given SIV-specific neutralizing antibodies.

Cell reports. Medicine
2026

Clinical composition of HIV/AIDS-related deaths during the COVID-19 pandemic: a nationwide natural experiment (2017-2024).

AIDS (London, England)
2026

Challenges in Diagnosis and Treatment of HIV-Negative Host Pulmonary Talaromyces marneffei in Non-Endemic Areas: A Case Report with a History of Pulmonary Tuberculosis.

Infection and drug resistance
2026

Alterations to the bronchial gene-expression effects of tobacco smoking in people living with HIV.

Journal of acquired immune deficiency syndromes (1999)
2026

Association of Perinatal HIV Exposure and HIV Disease Severity With BP in Youth.

Hypertension (Dallas, Tex. : 1979)
2026

Antiretroviral treatment does not prevent extrapulmonary tuberculosis during SIV/Mtb coinfection in macaques.

JCI insight
2026

Are Corticosteroids Truly Contraindicated in Pulmonary Kaposi Sarcoma?

Cureus
2026

Disseminated Talaromyces Marneffei Infection as the Initial Manifestation of Acute Human Immunodeficiency Virus Infection: A Case Report and Literature Review.

Open forum infectious diseases
2026

Anticholinergic burden interacts with age and AIDS history to amplify frailty in people with HIV.

British journal of clinical pharmacology
2026

The HIV/AIDS response as we knew it is over: Where do we go from here?

Journal of the International AIDS Society
2026

Relationships between family functioning and HIV/AIDS-related preventive behaviors among young students with sexual experience.

Frontiers in public health
2026

Cardiovascular system characteristics in HIV/AIDS patients with talaromycosis.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
2026

Single-step duplex CRISPR coupled with lateral flow assay for point-of-care detection of human immunodeficiency virus and Treponema pallidum.

Analytical methods : advancing methods and applications
2026

Gut microbiota: a novel target for traditional Chinese medicine in the treatment of HIV/AIDS immunological non-responders.

Chinese journal of natural medicines
2026

Brain Lesions Associated with Human Immunodeficiency Virus Infection in the Antiretroviral Therapy Era: A Single-center Experience in Japan.

Neurologia medico-chirurgica
2026

Effectiveness of a Digital Awareness App in HIV/AIDS Mitigation Among Transgender Individuals in Rawalpindi District: Protocol for a Quasi-Experimental Study.

JMIR research protocols
2026

Dissecting the steps in early simian immunodeficiency virus dissemination following mucosal and intravenous infection of rhesus macaques.

Journal of virology
2026

Analytical techniques for laboratory testing of HIV: a systematic review.

Journal of microbiological methods
2026

A Case of Human Immunodeficiency Virus (HIV) Infection Leading to Acquired Immunodeficiency Syndrome (AIDS)-Related Pneumocystis Pneumonia.

Cureus
2026

Immunogenicity and safety of two doses of the four-component recombinant meningococcal B (4CMenB) vaccine in adults with immunodeficiency.

Vaccine
2026

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

Science immunology
2026

Prevalence and predictors of virological failure and quality of life of people with HIV/AIDS at a Municipal Hospital, Volta Region -Ghana: A cross-sectional study.

PloS one
2026

NADCdb: A Joint Transcriptomic Database for Non-AIDS-Defining Cancer Research in HIV-Positive Individuals.

International journal of molecular sciences
2026

Short-cycle three-day-per-week efavirenz/emtricitabine/tenofovir disoproxil fumarate therapy: a seven-year extension study.

The Journal of antimicrobial chemotherapy
2026

Early signs, late action: missed HIV testing opportunities in routine clinical practice.

Sexually transmitted infections
2026

Sources of information on HIV/AIDS used by adolescents and young people: A scoping review protocol.

PloS one
2026

Clinical and Molecular Perspectives on Epidermodysplasia Verruciformis.

International journal of dermatology
2026

The Prevalence and Influencing Factors of Frailty Among Middle-Aged and Older Adults With HIV/AIDS From a Global Perspective: A Systematic Review and Meta-Analysis.

Geriatrics &amp; gerontology international
2025

Validation of a Pediatric Cognitive Assessment Tool to Advance Knowledge on Children's Cognitive Development, Health Risk Factors, and Health-promoting Interventions in Sub-Saharan Regions.

Innovations in clinical neuroscience
2025

Immunogenicity and protection mediated by dmLT and alum adjuvants for an HIV-1 vaccine.

Frontiers in immunology
2026

Spatiotemporal aggregation and population distribution characteristics of HIV/AIDS in Nanchang city: A monitoring analysis from 2012-2021.

PloS one
2026

Significance and implementation challenges of participatory monitoring and evaluation of HIV/AIDS programmes in local government authorities: Evidence from Iringa Region, Tanzania.

Evaluation and program planning
2026

Modelling and analyzing the transmission dynamics of HIV/AIDS epidemic in China.

Journal of biological dynamics
2026

HIV Research Priorities in Iran: Reflections from the Early Years to a New Framework for Action.

Iranian journal of medical sciences
2026

Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach.

Iranian journal of medical sciences
2025

Multivariable analysis of bone mass reduction risk prediction and anxiety status in male HIV/AIDS patients.

Frontiers in reproductive health
2026

Initial sites of SIV rebound after antiretroviral treatment cessation in rhesus macaques.

Nature microbiology
2026

Psychological Well-Being Challenges and Associated Coping Mechanisms of HIV/AIDS Counselors in the Volta Region of Ghana: A Descriptive Phenomenological Study.

Journal of the International Association of Providers of AIDS Care
2026

Boosting SIV-specific CD8+ T cell responses prior to ART interruption extends time to SIVmac239 rebound.

The Journal of clinical investigation
2026

Health Literacy, Knowledge of HIV/AIDS, and Public Stigma Among General Citizens of Japan: An Online Cross-Sectional Survey.

Journal of the International Association of Providers of AIDS Care
2025

Association of medication regimen complexity index with ADRs in HIV/AIDS patients: a retrospective cohort study.

Frontiers in pharmacology
2026

A global overview of microsporidia infection in HIV/AIDS patients: an updated systematic review and meta-analysis.

International health
2026

Severe ARDS without exanthem: atypical measles in advanced HIV.

Transactions of the Royal Society of Tropical Medicine and Hygiene
2026

SHIV.D Infection Alters Production and Protein Composition of Myeloid-Derived Extracellular Vesicles.

International journal of molecular sciences
2025

Prevalence and Risk Factors of Liver Fibrosis in People Living with HIV/Acquired Immunodeficiency Syndrome.

Journal of global infectious diseases
2026

Comparative evaluation of nine lateral flow assays for FIV antibody detection using an in-house ELISA as a reference method.

BMC veterinary research
2026

Finite Mixtures of Multivariate t $$ t $$ Linear Mixed-Effects Models for Censored Longitudinal Data With Concomitant Covariates.

Statistics in medicine
2025

Adherence to antiretroviral therapy among female sex workers in Kampala, Uganda.

Journal of public health in Africa
2026

[Progress in research of prevalence of HIV/AIDS and influencing factors in transgender women].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
2026

[Analysis on HIV/AIDS related topics of public concern on TikTok platform: based on latent dirichlet allocation model].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
2026

The relationship between development indicators and HIV epidemiology: a global perspective on social determinants.

AIDS care
2026

Psychological responses to interval and continuous exercise in people living with HIV: A single-blind, counterbalanced, crossover study.

HIV medicine
2026

Early Diagnostic Value of Contrast-Enhanced MRI in Distinguishing Toxoplasmic Encephalitis from CNS Lymphoma: A Case Report of AIDS with Seronegative Toxoplasmosis.

Journal of the International Association of Providers of AIDS Care
2026

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous-venous extracorporeal membrane oxygenation (VV-ECMO): A case report.

British journal of clinical pharmacology
2026

Research priorities for advanced HIV disease in Latin America and the Caribbean region: a modified Delphi study.

Journal of the International AIDS Society
2026

Sexual Dysfunction and Hypoactive Sexual Desire in Women Living With HIV in Ceará, Brazil: A Cross-Sectional Study.

The Journal of the Association of Nurses in AIDS Care : JANAC
2025

What prevention approaches and technologies are we using? Analysing HIV and AIDS communication campaigns in Brazil.

Ciencia &amp; saude coletiva
2026

Preventing the heterosexual epidemic: Responses and contingencies during the HIV/AIDS crisis in Denmark, 1981-1997.

Medical history
2026

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2026

Clinical outcomes after switching from sulfamethoxazole-trimethoprim to atovaquone due to intolerance in patients with non-HIV Pneumocystis pneumonia: a single-center retrospective study.

Journal of pharmaceutical health care and sciences
2026

CRISPR Applications in HIV Management - Prevention, Diagnosis, Monitoring and Treatment.

Current HIV/AIDS reports
2026

Anti-IL-15 treatment reduces acute lentivirus inflammation and signaling in the brain.

Cell reports. Medicine
2026

CXCL9 and CXCL10 Induce Expression of Nociceptive Ion Channels in Primary Sensory Neurons in Models of HIV-Associated Distal Sensory Polyneuropathy.

International journal of molecular sciences
2026

Efficacy, Effectiveness, and Safety of Treatment Regimens for Histoplasmosis and Tuberculosis Coinfection in Patients With Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome: A Systematic Review With Meta-Analysis Protocol.

Health science reports
2026

Successful desensitization to liposomal amphotericin B for the treatment of disseminated cryptococcosis in pregnancy: a case report.

ASM case reports
2026

Coumarin-stavudine (d4T) novel hybrid ProTides with dual-functionality and enhanced anti-HIV activity.

European journal of medicinal chemistry
2026

Concurrent cryptococcal and dengue meningoencephalitis as initial presentation of human immunodeficiency virus infection in a patient from arbovirus-endemic northeastern Brazil: a case report.

BMC infectious diseases
2026

Cachexia phenotype in community-dwelling, middle-aged and older adults and its impacts on intrinsic capacity and mortality: A pooled analysis of three cohorts.

Clinical nutrition (Edinburgh, Scotland)
2025

Disclosure and peer support in prevention of mother-to-child transmission of human immunodeficiency virus: Evidence from Rwanda.

World journal of virology
2025

Korean HIV/AIDS Cohort Study: Past Achievements, Present Directions, and Future Perspectives.

Jugan geon-gang gwa jilbyeong
2025

History and Current Status of the HIV/AIDS Supporting Network System.

Jugan geon-gang gwa jilbyeong
2025

Overview of the National HIV/AIDS Prevention and Control Program in the Republic of Korea.

Jugan geon-gang gwa jilbyeong
2025

Status of Notifiable Infectious Diseases Reporting in the Republic of Korea: 2024 Surveillance Report.

Jugan geon-gang gwa jilbyeong
2026

The Applications of Machine Learning to Prognostic Modeling for Human Immunodeficiency Virus: A Protocol for a Scoping Review.

Health science reports
2026

Frequency of CCR5-Δ32, CCR2-64I, and SDF1-3'A Mutations in People with HIV Diagnoses and HIV Negative Participant in Khuzestan Province, Iran.

AIDS research and human retroviruses
2025

One-year mortality among adults with advanced HIV in sub-Saharan Africa: a systematic review and meta-analysis.

AIDS (London, England)
2025

Professional Nurses' Experiences Regarding Antiretroviral Adherence by Incarcerated Individuals Living with HIV and AIDS in Correctional Services.

International journal of environmental research and public health
2025

Prevalence of Cryptococcal Antigenemia Among Human Immunodeficiency Virus Infection or Acquired Immunodeficiency Syndrome Patients Attending the Retroviral Clinic in University of Maiduguri Teaching Hospital.

Nigerian journal of clinical practice
2025

Divergent trends of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), syphilis, and gonorrhea in China: a national age-period-cohort analysis, 2006-2020.

Frontiers in public health
2025

Combating HIV/AIDS prevalence in South Africa: Does foreign aid play a significant role?

African journal of reproductive health
2025

Barriers experienced by patients in adhering to antiretroviral treatment in a mobile clinic in KwaZulu-Natal, South Africa.

African journal of reproductive health
2026

A subcutaneous implant that releases islatravir provides long-lasting protection against vaginal SHIV infection in macaques.

Journal of controlled release : official journal of the Controlled Release Society
2025

Temporal analysis and factors associated with visceral leishmaniasis-HIV-AIDS coinfection in an endemic region of Brazil.

PLoS neglected tropical diseases
2026

Clinical and laboratory predictors of mortality in HIV/AIDS patients with disseminated histoplasmosis: A cohort study in a hyperendemic region of Northeast Brazil.

Medical mycology
2025

Analysis of influencing factors of AIDS epidemic in Kunming based on PCA-GWR method.

Frontiers in public health
2025

Revolutionizing antiviral therapy: harnessing nanotechnology to unlock the power of phytoconstituents.

Expert opinion on drug delivery
2025

In vitro Control of RNA Virus Infections by M1-Polarized Human Monocyte-Derived Macrophages.

The new microbiologica
2025

Listeria monocytogenes bacteremia in an AIDS patient during pregnancy: A case report.

Medicine
2026

Application of a novel branched-DNA assay to quantify killer immunoglobulin-like receptor (KIR) mRNA expression identifies tissue compartmentalization in naïve and SIV-infected rhesus macaques.

Journal of immunological methods
2025

Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy.

Frontiers in cellular and infection microbiology
2025

Early neurosyphilis on the rise: A Post-Covid reality check in people living with human immunodeficiency virus/acquired immunodeficiency syndrome.

Indian journal of sexually transmitted diseases and AIDS
2026

Long-term treatment outcomes among AIDS patients with and without talaromycosis: A retrospective study.

Journal de mycologie medicale
2025

HIV/AIDS compartmental model analysis with drug resistance treatment, vertical transmission, and optimal control theory.

Scientific reports
2025

Censoring-robust estimation in fixed sample time-to-event clinical trials with adaptive randomization.

Biometrics
2025

Comprehensive HIV/AIDS knowledge among Rwandan men aged 50-59: evidence from the 2019-20 RDHS.

AIDS research and therapy
2025

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AIDS in the Brazilian Amazon: epidemiological trends and disparities across states.

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A comparative analysis of compliance with HIV/AIDS clinical care indicators and treatment outcomes: A case study of the Democratic Republic of Congo and South Africa.

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Comparison of HIV/AIDS death estimates for 2019 between GBD 2019 and WHO mortality databases.

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Moxibustion for human immunodeficiency virus and acquired immunodeficiency syndrome and its complications: a systematic review of randomized controlled trials.

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Preclinical evaluation of long-acting cabotegravir and rilpivirine for HIV post-exposure prophylaxis in a macaque model.

EBioMedicine
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Hematological abnormalities and associated factors among adult HIV/AIDS patients on antiretroviral therapy at Hiwot Fana Comprehensive Specialized Hospital: A cross sectional study.

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Mathematical modeling and neural network based fitting of HIV/AIDS data in the workingclass population case study from Ethiopia.

Scientific reports
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BMC immunology
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Metagenomic next-generation sequencing diagnoses Talaromyces marneffei infections: case report and review.

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International journal of STD &amp; AIDS
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A decreased proportion of naïve MAIT cells is associated with the incomplete immune reconstitution in antiretroviral therapy-treated HIV-1 patients.

Virologica Sinica
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Micro Level Construction of HIV/AIDS Disease Causality, Retribution and Changes in Living Arrangement with People Living With HIV/AIDS in a Rural Setting in Ghana: A Qualitative Study.

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Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect.

The Journal of experimental medicine
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Spirocyclopentane as a Novel Scaffold for Potent Ghrelin Receptor Full Agonists.

Journal of medicinal chemistry
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Seroprevalence and genetic diversity of feline immunodeficiency virus in outdoor cats in France.

Veterinary research
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A Rare Presentation of Synchronous Pneumocystis Pneumonia and Cutaneous Nocardiosis on 18F-FDG PET/CT.

Nuclear medicine and molecular imaging
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Ciencia &amp; saude coletiva
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[Genetic Diversity and Drug Resistance of Human Immunodeficiency Virus from Newly Diagnosed Human Immunodeficiency Virus-positive in Korean, 2022-2023].

Jugan geon-gang gwa jilbyeong
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[Foreigner HIV/AIDS Notifications in the Republic of Korea in 2023].

Jugan geon-gang gwa jilbyeong
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Risk factors of metabolic dysfunction-associated fatty liver disease in people living with HIV receiving antiretroviral therapy.

AIDS (London, England)
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Ancestral reconstruction supports that loss of Nef-mediated T cell modulation coincided with the emergence of pathogenic lentiviruses.

Journal of virology
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HIV/AIDS knowledge and educational needs among Sudanese health science students: A cross-sectional study.

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PLoS pathogens
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PLoS medicine
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Molecular psychiatry
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Acta neuropathologica communications
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DEN open
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Journal of preventive medicine and hygiene
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Nature communications
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Surfactant-based drug delivery strategies for HIV/AIDS therapy: advances in formulation and clinical translation.

Pharmaceutical development and technology
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Assessment of HIV/AIDS-related stigma and knowledge gaps among healthcare providers in Egypt.

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Communications biology
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Computers in biology and medicine
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Virology journal
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Magical Contagion and Aids Risk Perception in a College Population.

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. BCG Infection Following Therapy of Infant Acute Lymphoblastic Leukemia.
    Pediatric blood &amp; cancer· 2026· PMID 41834323mais citado
  2. Resilient in adversity: Innovative treatment support interventions in facilitating ART adherence among young adults living with HIV in the informal settlements of Kibera, Nairobi.
    PloS one· 2026· PMID 41770772mais citado
  3. Delayed viral rebound post-ART interruption in infant macaques given SIV-specific neutralizing antibodies.
    Cell reports. Medicine· 2026· PMID 41742404mais citado
  4. Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.
    Science immunology· 2026· PMID 41686912mais citado
  5. Prevalence and predictors of virological failure and quality of life of people with HIV/AIDS at a Municipal Hospital, Volta Region -Ghana: A cross-sectional study.
    PloS one· 2026· PMID 41686774mais citado
  6. Prevalence of Latent Tuberculosis Infection in Vulnerable Groups in the State of Santa Catarina, Brazil.
    Rev Soc Bras Med Trop· 2026· PMID 41983896recente
  7. Identification of Clinical Characteristics and Risk Factors of Invasive Pulmonary Aspergillosis in Patients with Acquired Immunodeficiency Syndrome: A Retrospective Study.
    Infect Drug Resist· 2026· PMID 41983108recente
  8. Astragalus polysaccharide promotes latent HIV-1 reactivation via exosome-mediated modulation of the PI3K/AKT/NF-κB axis.
    Extracell Vesicles Circ Nucl Acids· 2026· PMID 41983051recente
  9. Clinical Characteristics and Risk Factors for Syphilis Among People Living With Human Immunodeficiency Virus: A Nationwide Population-Based Cohort Study in Korea.
    J Korean Med Sci· 2026· PMID 41978926recente
  10. A Case Report of a Forehead Abscess Caused by Nocardia concava in a Patient with AIDS.
    J Vis Exp· 2026· PMID 41973623recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:310050(Orphanet)
  2. MONDO:0017769(MONDO)
  3. GARD:21359(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q12199(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

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Imunodeficiência adquirida
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Imunodeficiência adquirida

ORPHA:310050 · MONDO:0017769
CID-10
B2424. · Doença pelo vírus da imunodeficiência humana [HIV] não especificada
CID-11
MedGen
UMLS
C0001175
Repurposing
4 candidatos
cidofovirDNA polymerase inhibitor
foscarnetnucleoside reverse transcriptase inhibitor
lamivudine
+1 outros
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