Raras
Buscar doenças, sintomas, genes...
Intoxicação por chumbo
ORPHA:330015CID-10 · T56.0CID-11 · NE61DOENÇA RARA

Foi relatado que (5 ug/dL) pode levar a efeitos irreversíveis, como perda da capacidade de raciocínio e memória, dificuldade de concentração, mudanças de comportamento, dislexia, Transtorno de Déficit de Atenção, pressão alta, problemas nos rins, danos ao sistema imunológico e danos aos órgãos reprodutores.

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Introdução

O que você precisa saber de cara

📋

Foi relatado que (5 ug/dL) pode levar a efeitos irreversíveis, como perda da capacidade de raciocínio e memória, dificuldade de concentração, mudanças de comportamento, dislexia, Transtorno de Déficit de Atenção, pressão alta, problemas nos rins, danos ao sistema imunológico e danos aos órgãos reprodutores.

Pesquisas ativas
1 ensaio
29 total registrados no ClinicalTrials.gov
Publicações científicas
6.265 artigos
Último publicado: 2026 Mar 12

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-9 / 100 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
2.3
Europe
Início
All ages
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: T56.0
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🧠
Neurológico
8 sintomas
🫃
Digestivo
5 sintomas
🫘
Rins
3 sintomas
📏
Crescimento
3 sintomas
💪
Músculos
2 sintomas
🛡️
Imunológico
2 sintomas

+ 31 sintomas em outras categorias

Características mais comuns

55%prev.
Distensão abdominal
Frequente (79-30%)
55%prev.
Fadiga
Frequente (79-30%)
55%prev.
Vômitos
Frequente (79-30%)
55%prev.
Náusea
Frequente (79-30%)
55%prev.
Dor abdominal
Frequente (79-30%)
55%prev.
Hipertensão
Frequente (79-30%)
62sintomas
Frequente (8)
Ocasional (26)
Muito raro (28)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 62 características clínicas mais associadas, ordenadas por frequência.

Distensão abdominalAbdominal distention
Frequente (79-30%)55%
FadigaFatigue
Frequente (79-30%)55%
VômitosVomiting
Frequente (79-30%)55%
NáuseaNausea
Frequente (79-30%)55%
Dor abdominalAbdominal pain
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico6.265PubMed
Últimos 10 anos200publicações
Pico2025112 papers
Linha do tempo
2026Hoje · 2026🧪 1991Primeiro ensaio clínico📈 2025Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
Aprovado1
3Fase 31
·Pré-clínico18
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 20 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Intoxicação por chumbo

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

29 ensaios clínicos encontrados, 1 ativos.

Distribuição por fase
NCT03640143 · Effectiveness of Environmental Measures to Eliminate the Ris…Em breve
NCT04498845 · RECLEAN Pilot StudyEncerrado
NA
NCT05950386 · Effects of Lead Exposure on Ferroptosis PathwayUNKNOWN
NCT05744752 · Effects of Allium Sativum and Moringa Oleifera Extract on De…UNKNOWN
NA
NCT05265572 · Evaluation of the Impact of a Personal and Domestic Hygiene …UNKNOWN
NA
NCT03408275 · Dietry Pattern and Lead Levels in PregnancyConcluído
NCT03256383 · Plan for Testing Fingerstick Bloods on Magellan SystemsUNKNOWN
NCT00012480 · Effect of Environmental Exposures on the Egg Fertilizing Abi…Concluído
NCT00013858 · Environmental Contaminants and Infant DevelopmentConcluído
NCT00013819 · Exposure, Dose, Body Burden and Health Effects of LeadConcluído
NCT00552630 · Penicillamine Chelation for Children With Lead PoisoningCancelado
PHASE2, PHASE3
NCT02346188 · Effects of Iron and/or Zinc Supplementation in Mexican Schoo…Concluído
NA
NCT01739166 · QI Study of a Practice Facilitator's Impact in Working With …Concluído
NA
NCT00285532 · Identifying Residential Hazards Using Home Test KitsConcluído
NCT00285610 · Early Exposure to Lead and Adult Antisocial OutcomesConcluído
NCT01573013 · Iron Fortification Trail Using NaFeEDTA in Iron Deficient Le…Concluído
NA
NCT00926406 · Environmental Exposure to Lead and Its Health Effects on Pat…UNKNOWN
NA
NCT00931905 · Homeopathic Preparation Plumbum Metallicum for Lead Poisonin…Concluído
PHASE4
NCT00374894 · The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi…Concluído
NCT00011661 · Social Network Based Intervention to Reduce Lead Exposure Am…Concluído
NA
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
977 papers (10 anos)

Mostrando amostra de 200 publicações de um total de 977

#1

Behavioral shifts mask the success of legislation and outreach for endangered species recovery.

Nature communications2026 Mar 18

A fundamental challenge in conservation is assessing the efficacy of recovery actions to optimize endangered species management. Considerable recent attention has focused on effective measures to counter the endangerment of avian scavengers, which have declined worldwide, primarily due to poisoning. One iconic example is efforts to recover the critically endangered California condor (Gymnogyps californianus), whose leading cause of death is poisoning from ingesting lead-based ammunition in carcasses. Despite enormous resources expended in California, USA, including implementation of public outreach campaigns and two legislative bans on lead ammunition, lead-related mortality of condors has increased. Here we show that two types of behavioral shifts explain the observed increases in condor lead exposure: wilder foraging and ranging by condors and increased shooting of wild pigs (Sus scrofa) by humans. After accounting for these trends, we show that both lead ammunition bans and public outreach efforts have significantly reduced condor blood lead levels in California, lowering mortality. Our analyses uncover a dynamic in which changing ecological conditions mask the true efficacy of legislation and outreach. Given rapid global change, such dynamics are likely operating in many settings, underscoring the importance of comprehensive evaluations of recovery actions, which can be obscured by shifting behaviors and threats.

#2

A standardized osteometric method for identifying Iberian raptors from skeletal remains.

Research in veterinary science2026 May

Raptors suffer high mortality rates due to anthropogenic threats, such as electrocution from power lines or lead poisoning, so the specific identification of skeletal remains is essential for establishing monitoring and protection programmes. This study developed and validated a standardized osteometric method for measuring long bones and craniopelvic bones from skeletal remains to identify raptor species. A database of 26 species of Iberian raptors (n = 853) was developed based on 11 measurements of 9 bones, including the ulna, sternum, femur, humerus, tarsometatarsus, tibiotarsus, and radius, as well as the synsacrum length and postacetabular ilium width and length and width of the skull. Missing values were estimated using multiple linear regression, and canonical discriminant analysis was applied to correct and modify the databases. Cross-validation was added to this analysis. Additionally, the obtained model was verified using external radiographs. The highest percentage of success was obtained with the tarsometatarsus-ulna combination (94.53%), followed by tarsometatarsus-radius (94.05%) and tarsometatarsus-humerus (93.02%), when two bone lengths were combined. When a third measurement was incorporated, the tarsometatarsus-ulna-femur combination achieved a 99.45% correct classification rate. In blind verification testing, the radiographs of 15 individuals, the tarsometatarsus-ulna model correctly classified all samples, achieving a 100% success rate. These results show that the study method provides a simple and replicable protocol for identifying raptor species from incomplete skeletal remains. This optimizes the monitoring of mortality and supporting conservation measures.

#3

Epidemiologic Trends in Pediatric Lead Poisoning at Freestanding Children's Hospitals, 2016-2023.

Hospital pediatrics2026 Jan 01

Elevated blood lead levels are still prevalent among children in the United States, and there continue to be published reports of severe childhood lead poisoning across the United States. However, the epidemiology of hospital encounters for severe lead poisoning is still unknown. We included encounters for children with a primary diagnosis of lead poisoning using Pediatric Hospital Information System data from 2016 to 2023. We used descriptive statistics to characterize patient sociodemographic factors, clinical characteristics, and hospital utilization, as well as Poisson regression accounting for hospital state-level variation, to estimate lead poisoning rates by patient race and ethnicity, insurance payor, urbanicity, and Childhood Opportunity Index (COI) level. There were 845 inpatient hospitalizations and 1137 emergency department visits for lead poisoning across 47 hospitals, resulting in over $4.5 million mean cumulative annual billed charges. Compared with patients who identified as white, non-Hispanic, patients who identified as Asian, non-Hispanic (incidence rate ratio [IRR], 1.75); Black, non-Hispanic (IRR, 1.44); and multiracial, non-Hispanic (IRR, 2.26) had significantly higher rates of lead poisoning encounters. Those with public insurance had higher rates of encounters compared with those with commercial insurance (IRR, 2.14). Patients in rural zip codes had significantly higher rates of encounters than patients in urban zip codes (IRR, 1.51). Patients in low- (IRR, 1.79) and very low-COI (IRR, 3.22) zip codes had significantly higher rates of encounters compared with those in very high-COI zip codes. This study finds that severe lead poisoning remains a substantial health concern. We found significant disparities in the rate of encounters by sociodemographic factors that warrant further action.

#4

Encephalopathy Due to Lead Poisoning in Two Brothers 4 Years Apart.

Indian journal of pediatrics2026 Mar 24
#5

A Mother's Calling: Interdisciplinary, Trauma-Informed Care for Lead Poisoning.

Hospital pediatrics2026 Mar 17

Publicações recentes

Ver todas no PubMed

📚 EuropePMC3.799 artigos no totalmostrando 191

2026

Encephalopathy Due to Lead Poisoning in Two Brothers 4 Years Apart.

Indian journal of pediatrics
2026

Behavioral shifts mask the success of legislation and outreach for endangered species recovery.

Nature communications
2026

Forensic Policy Considerations of Childhood Lead Toxicity.

The journal of the American Academy of Psychiatry and the Law
2026

A Mother's Calling: Interdisciplinary, Trauma-Informed Care for Lead Poisoning.

Hospital pediatrics
2026

Case series: from ventilation failure to substitution success in occupational lead poisoning at a Korean indoor firing range.

Annals of occupational and environmental medicine
2026

Historical Redlining and Racial Disparities in Child Blood Lead Levels in Southeastern Wisconsin.

Journal of racial and ethnic health disparities
2026

Acute Haemolytic Anaemia Secondary to Lead Poisoning: A Case Report.

Cureus
2026

Protective role and mechanism of flavonoids from Smilax glabra Roxb. against lead-induced neurotoxicity and hematotoxicity in Daniorerio.

Journal of ethnopharmacology
2026

A standardized osteometric method for identifying Iberian raptors from skeletal remains.

Research in veterinary science
2026

Lead Toxicity Masquerading as Autoimmune Haemolytic Anaemia: A Diagnostic Pitfall in Unexplained Anaemia.

Cureus
2026

Lead Poisoning Revealed by Unexplained Abdominal Pain and Anemia in a Young Adult: A Diagnostic Challenge.

Clinical case reports
2026

Pharmacological potential of aqueous extract of Ononis natrix in mitigating early-life lead toxicity: behavioral, biochemical, histological, and immunohistochemical evaluation.

Phytomedicine : international journal of phytotherapy and phytopharmacology
2026

Occurrence of acute lead toxicosis in western Canadian cattle herds: A decade of diagnostic case records (2014 to 2024).

The Canadian veterinary journal = La revue veterinaire canadienne
2026

Lead Toxicity Testing in the Asia-Pacific - Practices, Challenges, and Policy Insights: An APFCB Communication and Publications Committee Survey report.

EJIFCC
2026

Integrating Environmental Health into Primary Care: Addressing Gaps in Screening and Practice.

Primary care
2026

[Analysis of blood lead levels and occupational health risk assessment of lead-exposed population in Jiangsu Province in 2023].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
2026

Gallic and ascorbic acids either alone or combined contribute to ameliorating lead-induced cerebral neurotoxicity in rats: A histological and immunohistochemical study.

Neurotoxicology
2026

From awareness to action: enhancing mothers' knowledge and practices on lead exposure among young children in the Bani-Khaled Village, Minia Governorate.

BMC public health
2026

A case report of an unconventional chronic lead poisoning resulting from daily eyelid application of kohl.

Practical laboratory medicine
2026

Occupational lead exposure induces oxidative stress, pulmonary dysfunction, and reduced exercise capacity: A cross-sectional study.

Toxicology letters
2026

Lead poisoning in southeast Asia: an urgent call for action.

Lancet (London, England)
2026

An overview of lead toxicity and its therapeutic strategies.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
2026

Impact of safety interventions on behavioural changes and blood lead levels in Thai fishnet sinker workers.

Occupational and environmental medicine
2026

Advances in the clinical applications of sodium thiosulphate.

Annals of medicine
2025

The Minimally Invasive Posterior Approach: A Novel Technique for Shrapnel Removal in the Knee.

Case reports in orthopedics
2026

Alleviating perovskite toxicity and inhibition of lead leakage for sustainable perovskite solar cells.

Nanoscale
2026

Epidemiologic Trends in Pediatric Lead Poisoning at Freestanding Children's Hospitals, 2016-2023.

Hospital pediatrics
2026

Challenges of Importing Residential Lead Paint Inspection and Risk Assessment Reports Into a National Database.

Journal of public health management and practice : JPHMP
2025

[Changes in hygiene standards for lead in the context of indoor shooting range workers exposure].

Medycyna pracy
2026

A Case Report of Adult Lead Poisoning following the Use of Nonprescription Ayurvedic Medication in Germany.

Complementary medicine research
2025

Lead in interior and exterior paints of kindergartens in Chişinău, Republic of Moldova.

Scientific reports
2025

Lead Exposure in South African Waterfowl: Implications for Conservation and Human Health.

Archives of environmental contamination and toxicology
2025

Case Report: Severe lead poisoning due to exposure to ayurvedic herbal medicine.

Frontiers in pediatrics
2025

Personalized lead exposure information and preventive behaviors in Ivory Coast: Insights from a pilot study.

PloS one
2025

Utilization of the environmental lead in soil criterion significantly overestimates worker exposure to lead-containing dusts that may be present within South Australian government buildings.

Annals of work exposures and health
2025

Efficacy of Bacopa monnieri in Mitigating Lead-Induced Blood Toxicity in Swiss Albino Mice Compared to Synthetic Antioxidants.

Biological trace element research
2025

[Lead poisoning diagnosed in a patient with anemia accompanied by abdominal pain].

[Rinsho ketsueki] The Japanese journal of clinical hematology
2025

Unexpected High Blood Lead Levels in a Remote Indigenous Community in the Northeastern Peruvian Amazon.

Toxics
2025

Dual-Action Cellular Nanoparticles for Effective Lead (Pb2+) Detoxification.

ACS nano
2025

Did lead poisoning help drive human evolution?

Science (New York, N.Y.)
2025

[Establishment and evaluation of lead-exposed osteoporosis model in rats].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
2025

Elevated blood lead levels and associated risk factors among school children in a non-industrialized city in Indonesia.

PloS one
2025

What's in Your Soil? A Citywide Investigation of the Importance of Soil Lead for Predicting Elevated Blood Lead Levels in Chicago.

GeoHealth
2025

Comparative neuroprotective efficacy of N-acetylcysteine and naringin in lead-induced neurotoxicity: Restoration of BDNF, neurotransmitters, and cognitive function.

Morphologie : bulletin de l'Association des anatomistes
2025

Creating a Community Resource for Neuropsychological Assessments After a Lead Exposure: Process and Findings.

Disaster medicine and public health preparedness
2025

Astaxanthin Alleviates Lead-Induced Toxicity by Restoring Hepatic and Gut-Liver Axis Homeostasis Through Multidimensional Metabolic and Antioxidative Pathways.

Food science &amp; nutrition
2025

Severe lead poisoning from an old ceramic carafe exacerbated by an acidic beverage.

Clinical toxicology (Philadelphia, Pa.)
2026

Hepatoprotective effect of pyridoxal phosphate against lead poisoning by inhibiting Kupffer cell hyperplasia due to a decrease in oxidative stress associated with hepatic NF-kβ.

Naunyn-Schmiedeberg's archives of pharmacology
2025

Fatal Lead Toxicity From Ayurvedic Supplements in a Patient With Parkinson's Disease.

Cureus
2026

Prevention of Lead Exposure in the Perinatal Period.

Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
2025

Lead Bullet Burden: Widespread Lead Exposure in Wild Carnivores and Unseen Consequences of Feeding Lead-Shot Meat to Captive Cheetahs (Acinonyx jubatus).

Journal of wildlife diseases
2025

Lead Toxicity: A Case Report of a Rare and Potentially Underdiagnosed Condition in Nepal.

Clinical case reports
2025

Global, regional, and national burden of lead-attributable intellectual developmental disability in children and adolescents from 1990 to 2021, with projections up to 2040: the global burden of disease 2021 study.

European journal of pediatrics
2025

Hesperidin mitigates lead-induced neurotoxicity via TFEB-dependent restoration of mitochondrial function, oxidative balance, and neuroinflammation in rats.

Neurotoxicology
2026

A Patient With Liver Injury, Portal Hypertension, Anemia, and Peripheral Neuropathy.

Gastroenterology
2025

Lead Poisoning in the Americas: Sources, Regulations, Health Impacts, and Molecular Mechanisms.

Journal of xenobiotics
2025

Lead poisoning in a 10-year-old boy with cyclic vomiting as the first symptom: a case report.

Frontiers in pediatrics
2025

Lead Intoxication Related to Coriander Consumption: A Case Report From the United States.

Journal of preventive medicine and public health = Yebang Uihakhoe chi
2025

Heavy Metal Contamination: Sources, Health Impacts, and Sustainable Mitigation Strategies with Insights from Nigerian Case Studies.

F1000Research
2025

Prevalence of lead poisoning among artisanal gold miners in French Guiana in 2022: a multicenter cross-sectional observational survey.

BMC public health
2025

Lead exposure in Bihar, Eastern India: a risk assessment study.

Environmental geochemistry and health
2025

[Mechanism of Qizao oral liquid in the treatment of lead poisoning based on network pharmacology and molecular docking technology].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
2025

Eliminating lead-exposure in nebulization therapy by lead-free piezoelectric.

Nature communications
2026

Rapid detection of lead(II) with colorimetric optical sensors: calibration-free analysis demonstrated with semi-quantitative determination of urinary lead.

Talanta
2025

Modulation of Blood Lead Level and Liver Function Tests in Iranian Opium Users.

International journal of preventive medicine
2025

Fighting Lead Poisoning: Effective Conditions for Home-Based Education, Housing Remediation, and Relocation.

Toxics
2025

Principles of environmental medicine: an educational case study of lead poisoning in Beethoven.

Frontiers in public health
2025

Evaluation of a multicomponent child development intervention delivered through the government health system: a feasibility study.

BMJ global health
2025

Dose-Dependent Effects of Subchronic Lead Exposure on the Right Atrium and Right Ventricle of Rats: An In Vitro Investigation.

Cardiovascular toxicology
2025

The silent threat: A case series on lead-induced neurological and systemic damage.

Tropical doctor
2025

Impact of early adolescent lead exposure on brain function and response: Findings from a Chinese cohort.

Neurotoxicology
2026

EU regulation: An unprecedented opportunity to protect children's and wildlife health from the toxic effects of lead ammunition.

Ambio
2025

Tracking solutions to a persistent threat: spatial movement patterns reflect lead exposure in critically endangered California condors.

Ecotoxicology (London, England)
2025

Spirulina as a natural shield: a comprehensive review of its protective effects against lead toxicity.

Archives of toxicology
2025

Milk and Whole Blood Surveillance Following Lethal and Sublethal Lead Intoxication in a Michigan Dairy Herd.

Toxics
2025

Rare association between hepatotoxicity and sideroblastic anaemia after taking Garcinia cambogia-based dietary supplement.

BMJ case reports
2025

Unveiling a hidden hazard: lead poisoning from hobbyist activities and its long-term impact.

Annals of occupational and environmental medicine
2025

Lead as pharmakon: IQ, violence, and the racialization of a toxic element.

Medical anthropology quarterly
2025

A review of lead exposure source attributional studies.

The Science of the total environment
2025

Machine learning and explainable artificial intelligence to predict and interpret lead toxicity in pregnant women and unborn baby.

Frontiers in digital health
2025

Elevated lead levels as a risk factor for pediatric sensorineural hearing loss.

International journal of pediatric otorhinolaryngology
2026

Lead-Induced Nephrotoxicity and Its Therapeutic Interventions: An Updated Review.

Biological trace element research
2025

Field evaluation of grit supplementation as a tool to mitigate poisoning from lead shot legacy in waterbirds.

Environmental pollution (Barking, Essex : 1987)
2025

Oral Zeolite Therapy for Management of Mild to Moderate Lead Poisoning: A Randomized Clinical Trial.

Archives of academic emergency medicine
2025

Lead neurotoxicity in experimental models: A systematic review on effects on the cerebrum, cerebellum, and hippocampus.

Toxicology reports
2025

Investigating zinc's role in mitigating blood lead levels' toxicity on gut microbiota diversity: NHANES 2007-2010.

Toxicology letters
2025

Mostuea batesii Baker (Gelsemiaceae) root bark hydroethanolic extract unveil neuroprotective, antihypertensive, and antioxidant activities in rat model exposed to lead acetate.

Brain research
2025

Lead Poisoning in a Child.

The New England journal of medicine
2025

Ballistic projectile maxillofacial injuries in the context of human rights violations in Chile: A 5-case series.

Torture : quarterly journal on rehabilitation of torture victims and prevention of torture
2025

Case Report: Acute lead poisoning from bullet ingestion in a captive cheetah (Acinonyx jubatus) in Namibia: implications for wildlife management.

Frontiers in veterinary science
2025

Medical Surveillance of Occupational Lead Exposure Using the EPA's Toxics Release Inventory and Adult Blood Lead Epidemiology and Surveillance Program: Illinois, 2016-2023.

American journal of industrial medicine
2025

Elevated Blood Lead Levels in a Pregnant Woman and her Family from Traditional Kansa (Bronze) and Pital (Brass) Metalware - New York City, 2024.

MMWR. Morbidity and mortality weekly report
2025

[From the shotgun to the colon].

Semergen
2025

When Heavy Metals Weigh on the Mind: A Case Report of Neuropsychiatric Manifestations of Lead Toxicity From a Retained Bullet.

Cureus
2025

Panoramic lead-immune system interactome reveals diversified mechanisms of immunotoxicity upon chronic lead exposure.

Cell biology and toxicology
2025

Airborne lead exposures during artisanal lead mining and gold ore processing in Zamfara, Nigeria.

Journal of occupational and environmental hygiene
2025

Lead poisoning and its effects on bone density.

Scientific reports
2025

Lead systemic toxicity: A persistent problem for health.

Toxicology
2025

Investigation of Lead and Chromium Exposure After Consumption of Contaminated Cinnamon-Containing Applesauce - United States, November 2023-April 2024.

MMWR. Morbidity and mortality weekly report
2025

Reducing lead toxicity with advanced nanotechnology methods.

Naunyn-Schmiedeberg's archives of pharmacology
2025

Take the Lead on Lead: Feasibility of a Telemedicine-Based Clinic for Lead Poisoning Prevention and Management.

Academic pediatrics
2025

Evidence of lead poisoning and the co-occurrence of metabolic disease in Archaic/Early Classical (6th5th century BCE) Laurion, Greece.

Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen
2025

Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province.

Advanced biomedical research
2025

Prevalence and risk factors of elevated blood lead levels in 0-6-year-old children: a national cross-sectional study in China.

Frontiers in public health
2025

Corrigendum to "Clinical case analysis of 32 children aged 0-6 years with lead poisoning in Nanning, China".

Toxicology and industrial health
2025

Awareness of wildfire smoke among U.S. adults with and without asthma.

The Journal of asthma : official journal of the Association for the Care of Asthma
2025

Efficacy of Thunbergia laurifolia crude extracts against carcinogenic liver fluke, Opisthorchis viverrini.

Tropical biomedicine
2025

Role of Antioxidant Supplementation in Enhancing Chelation Therapy for Lead-Induced Oxidative Stress in Rats.

Cureus
2025

HEALTH RISK-FACTORS ASSOCIATED WITH LEAD EXPOSURE IN THE KVEMO KARTLI REGION OF GEORGIA.

Georgian medical news
2025

Combination of 10-hydroxy-decanoic acid and ZnO nanoparticles abrogates lead acetate-induced nephrotoxicity in rats: targeting oxidative stress and inflammatory signalling.

BMC pharmacology &amp; toxicology
2025

Estimation of the pooled mean blood lead levels of Indian children: Evidence from systematic review and meta-analysis.

Toxicology reports
2025

A more scientific blood lead reference value urgently needs to be updated in China: From a national and international insight.

Eco-Environment &amp; Health
2025

Recent advances in the clinical management of intoxication by five heavy metals: Mercury, lead, chromium, cadmium and arsenic.

Heliyon
2025

Routine paediatric lead screening questionnaires may not fully capture current risk factors.

BMJ case reports
2025

Lead pencil: a case of intractable abdominal pain secondary to lead poisoning.

The New Zealand medical journal
2025

Heterocyclic Coumarin Hybrids as Chemo Sensors of Neurotoxic Lead Ions in Safe Harmless Solvents and Ambient Temperature.

Journal of fluorescence
2025

Severe Lead Poisoning Managed with Combination Chelation Therapy: Report from a Resource-limited Country.

The Journal of the Association of Physicians of India
2025

Health risks related to environmental and occupational lead exposure.

Kardiologia polska
2024

Visualizing Parcel-Level Lead Risk Using an Exterior Housing-Based Index.

International journal of environmental research and public health
2025

Poisoned in their homes - Red blood cell abnormalities in lead-exposed residents of a Pakistani Industrial Zone.

Environmental monitoring and assessment
2025

Specialty laboratory testing for chronic abdominal pain in irritable bowel syndrome.

Scandinavian journal of gastroenterology
2025

Documentation of lead exposure-associated comorbidity among 4538 workers in China.

BMC public health
2025

Incorporating Parcel-Based Housing Conditions to Increase the Precision of Identifying Children With Elevated Blood Lead.

Journal of public health management and practice : JPHMP
2025

Cola beverage reduces risk of lead poisoning from accidental ingestion of contaminated soil particles in rat and swine models.

Nature communications
2025

Ameliorative role of bioactive compounds against lead-induced neurotoxicity.

Neuroscience
2025

Evaluation and treatment of lead toxicosis in rehabilitated avian species: 95 cases (2014-2023).

Journal of the American Veterinary Medical Association
2024

Les Cartes Porcelaine of the Mid 19th Century.

Journal of the history of dentistry
2024

Awareness and Knowledge of Lead Poisoning: A Street Survey in Three Municipalities of Georgia.

International journal of environmental research and public health
2025

Pan-European atmospheric lead pollution, enhanced blood lead levels, and cognitive decline from Roman-era mining and smelting.

Proceedings of the National Academy of Sciences of the United States of America
2025

Silent threats of lead-based paints in toys and households to children's health and development.

Journal of hazardous materials
2025

Rule Aims to Eliminate Risk of Lead Poisoning from Municipal Water Systems.

The American journal of nursing
2025

Heavy metals screening model in primary care: Experience in the Sierra Minera de Cartagena (Spain).

Medicina clinica
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Advancing Public Health Interventions: A Novel Surveillance System for Hazardous Consumer Products.

Journal of public health management and practice : JPHMP
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Can E-cigarettes Be the Source of Lead Toxicity?

Thoracic research and practice
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The Effectiveness of Levamisole and Broccoli in Lead Poisoning: Hematobiochemical Changes and Tissue Damage in the Liver, Kidney, and Spleen of Wistar Rats.

Journal of toxicology
2024

[The Pathography and Art of Beethoven, Revisited].

Brain and nerve = Shinkei kenkyu no shinpo
2025

A Public Health‒Community Partnership to Address Lead Poisoning in King County, Washington.

American journal of public health
2025

The effect of chelation on bone Pb stores in Pb poisoned children.

Journal of exposure science &amp; environmental epidemiology
2024

Pre-roman copper industry had no polluting impact on the global environment.

Scientific reports
2024

Lead Concentrations in Tissues of Pigeons (Columba livia) in the Urban Area of Comarca Lagunera, Mexico.

Toxics
2024

A New Source of Opioid and Lead Toxicity on the Block-Kamini: An Emerging Health Hazard-A Case Series.

Indian journal of psychological medicine
2025

A critical review on the removal of lead (heavy metal) by using various adsorbents from aqueous solution.

Environmental science and pollution research international
2024

Removing lead from the global economy.

The Lancet. Planetary health
2023

Development of a rapid zebrafish model for lead poisoning research and drugs screening.

Chemosphere
2024

Individualized support for breastfeeding in a case of elevated blood lead levels: A case report.

Toxicology reports
2024

Lead encephalopathy presenting as status epilepticus: a case report.

BMC pediatrics
2024

Presence and concentration of lead in keys and keyring items.

Occupational and environmental medicine
2025

Lead Toxicity and Maternal Exposure: Characterisation of Alveolar Bone Changes on Offspring Rats.

Biological trace element research
2024

[Research progress on Pb-induced neurotoxicity through glial cells].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
2024

Environmental Racism and Child Health.

Academic pediatrics
2024

Dietary silicate minerals relieving cadmium or lead poisoning in juvenile sea cucumber, Apostichopusjaponicus.

Marine environmental research
2025

Training Community Health Workers to Respond to Public Health Demands.

Journal of community health nursing
2024

Environment and Health: Heavy Metal Toxicity.

FP essentials
2024

Identifying High-Risk ZIP Codes for Childhood Lead Exposure: A Statewide ZCTA-Level Priority List for North Carolina.

North Carolina medical journal
2024

Invited Perspective: Protect and Serve-The Potential Role of Folate in Lead Risk Reduction.

Environmental health perspectives
2024

Pediatric Lead Chelation Managed During Critical Medication Shortages: Case Report and Literature Review.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
2025

Analyzing and Optimizing the Distribution of Blood Lead Level Testing for Children in New York City: A Data-Driven Approach.

Journal of urban health : bulletin of the New York Academy of Medicine
2024

Lead poisoning as a differential diagnosis in pediatric patients with chronic abdominal pain: a case-control study in Tehran-Iran.

BMC gastroenterology
2024

Lead Toxicity From Imported Jewelry.

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Low-Level, Early Life Lead Exposure and School Behavior.

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Severe Congenital Lead Poisoning in Siblings.

Pediatrics
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Effects of Blood Lead Levels <10 µg/dL in School-Age Children and Adolescents: A Scoping Review.

Pediatrics
2024

Blood Lead Testing and Follow-up Testing Among Children Hospitalized for Lead Poisoning.

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Sickle Cell Disease and Lead Poisoning in New York City, 2005-2019.

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Recently Recalled Children's Products Due to Lead Hazards.

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Universal Lead Testing in Pregnancy: A Call to Action.

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Traditional Eye Cosmetics and Cultural Powders as a Source of Lead Exposure.

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State-Level Childhood Lead Poisoning Prevention Policies and Practices in the United States: 2022-2023.

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The Challenges of Treating Lead Toxicity During the COVID-19 Pandemic.

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Collaboration for Lead Poisoning Prevention in Puerto Rico.

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Perspectives on Childhood Lead Exposure Prevention: Looking Back and Looking Ahead.

Pediatrics
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A Statewide Program to Test and Reduce Lead in Drinking Water at Schools and Child Cares.

Pediatrics
2024

Prenatal and early life lead exposure induced neurotoxicity.

Human &amp; experimental toxicology
2024

Lead toxicity mitigation effect of a Lactiplantibacillus plantarum-chondroitin sulfate complex revealed by microbiome and metabolomic analyses.

Food &amp; function
2024

A Possible Nocebo Effect in Children Following the Flint Water Crisis: Evidence From Schoolteacher Perceptions and Neuropsychological Evaluations.

Disaster medicine and public health preparedness
2024

Loss of cognitive function in Mexican children due to lead exposure and the associated economic costs.

Environmental research
2024

Lead Poisoning in Milwaukee: A Medical and Public Health Update.

WMJ : official publication of the State Medical Society of Wisconsin
2024

Association between relatively low blood lead levels and urinary δ-aminolevulinic acid concentrations among male workers at a Japanese battery factory.

Journal of occupational health
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Comparison of blood lead levels between battery recycling workers and controls in Northern Nigeria.

International journal of environmental health research
2024

Bone lead measurements of live condors in field to assess cumulative lead exposure.

Environmental science and pollution research international
2024

Chronic Lead Toxicity in a Family: A Case Report.

Cureus
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Berberine Hydrochloride Improves Cognitive Function and Hippocampal Antioxidant Status in Subchronic and Chronic Lead Poisoning.

Chinese journal of integrative medicine
2025

Therapeutic Effect of Smilax glabra Roxb. on Weaning Rats Against Pb-Induced Nephrotoxicity Based on Network Pharmacology.

Biological trace element research
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Searching for a Lead: Diagnosing a Rare Cause of Recurrent Intussusception.

Pediatrics in review
2024

Analysis of serum lead, copper, iron, and zinc and hematological parameters in battery smelting workers: assessing lead toxicity.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
2024

High lead contamination in Mother's breastmilk in Bihar (India): Health risk assessment of the feeding children.

Chemosphere
2024

Probable lead exposure in children from Chicago drinking water.

Pediatric dentistry
2024

Low-level, chronic ingestion of lead and cadmium: The unspoken danger for at-risk populations.

Journal of hazardous materials
2024

Implementation of a Childhood Lead Poisoning Prevention Program Data and Outcomes Management System Based on the Omaha System: A Pre-Post Evaluation.

Computers, informatics, nursing : CIN
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Knowledge, attitude, and practices related to lead pollution among adolescents and caregivers of young children living near Used Lead Acid Battery (ULAB) recycling sites in Bangladesh: a cross-sectional study.

BMC public health
2024

Investigating Blood Lead Levels and Its Health Effects on Employees of a Petroleum Industry and the Surrounding Residents: A Case Study of Kirkuk City, Iraq.

Journal of occupational and environmental medicine
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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Behavioral shifts mask the success of legislation and outreach for endangered species recovery.
    Nature communications· 2026· PMID 41851099mais citado
  2. A standardized osteometric method for identifying Iberian raptors from skeletal remains.
    Research in veterinary science· 2026· PMID 41780287mais citado
  3. Epidemiologic Trends in Pediatric Lead Poisoning at Freestanding Children's Hospitals, 2016-2023.
    Hospital pediatrics· 2026· PMID 41401830mais citado
  4. Encephalopathy Due to Lead Poisoning in Two Brothers 4 Years Apart.
    Indian journal of pediatrics· 2026· PMID 41872406mais citado
  5. A Mother's Calling: Interdisciplinary, Trauma-Informed Care for Lead Poisoning.
    Hospital pediatrics· 2026· PMID 41839224mais citado
  6. Lead chromate pigments dominate lead paints sold in Mexico.
    Ann Work Expo Health· 2026· PMID 41974173recente
  7. Review on lead poisoning in domestic animals: Prevention and control strategies.
    Vet Anim Sci· 2026· PMID 41971173recente
  8. Blood Lead Levels ≥ 45 mcg/dL in Pregnancy: An Observational Study.
    BJOG· 2026· PMID 41918451recente
  9. A survey of studies on blood lead concentrations and its health outcomes in Nepal: A review.
    Environ Toxicol Pharmacol· 2026· PMID 41895418recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:330015(Orphanet)
  2. MONDO:0018019(MONDO)
  3. GARD:21503(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Artigo Wikipedia(Wikipedia)
  6. Q110315(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Intoxicação por chumbo
Compêndio · Raras BR

Intoxicação por chumbo

ORPHA:330015 · MONDO:0018019
Prevalência
1-9 / 100 000
Herança
Not applicable
CID-10
T56.0 · Efeito tóxico do chumbo e seus compostos
CID-11
Ensaios
1 ativos
Início
All ages
Prevalência
2.3 (Europe)
MedGen
UMLS
C0023176
EuropePMC
Wikidata
Wikipedia
Papers 10a
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