Lipossarcoma pleomórfico

IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)

Sem fase

NCT06849986

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

Fase II

NCT06843967

Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients

Fase II

NCT02275286

Detection of Circulating Tumor Cells in Patients With Sarcomas

Sem fase

NCT02983539

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Publicações mais relevantes

Timeline de publicações

235 papers (10 anos)

#1

Myxoid Pleomorphic Liposarcoma Imitating Recurrent Traumatic Hemopericardium.

JACC. Case reports2026 Mar 19

Primary pericardial malignancies are rare, and myxoid tumors may mimic hemorrhagic pericardial effusions on imaging, leading to diagnostic delay. A 56-year-old man presented with pleuritic chest pain and was diagnosed with acute pericarditis and a presumed traumatic hemorrhagic pericardial effusion. Despite anti-inflammatory therapy and pericardiocentesis yielding bloody, lymphocyte-predominant fluid with negative cytology, he experienced rapid clinical deterioration. Repeat imaging revealed an encasing pericardial mass causing severe left atrial compression and functional mitral stenosis. Emergent surgical exploration identified a large solid pericardial tumor. Histopathology confirmed primary myxoid pleomorphic liposarcoma. The patient underwent surgical resection followed by adjuvant chemotherapy and radiotherapy. This case highlights the myxoid tumor's masquerade as a hemorrhagic effusion, the limitations of pericardial fluid cytology for sarcoma, and the hemodynamic consequences of external cardiac compression. Persistent or recurrent bloody pericardial effusions with atypical imaging features warrant suspicion for malignancy despite negative cytology.

#2

Surgical Strategies for Closure of Complex Posterior Trunk Defects in Myxoid Pleomorphic Liposarcoma: A Case Report and Literature Review.

Cureus2026 Feb

Myxoid pleomorphic liposarcoma (MPL) is an exceptionally rare subtype of liposarcoma characterized by an aggressive clinical course. Since its first description in 2009, fewer than a dozen cases have been reported, predominantly in pediatric populations and mediastinal locations. Reports in elderly patients and with posterior trunk involvement are exceedingly uncommon. We report the case of an 83-year-old male with a two-year history of progressive cervical-thoracic swelling, ultimately diagnosed as MPL on biopsy. Imaging revealed an 8.6 × 6.4 × 7.6 cm mass originating from the right cervico-thoracic paravertebral muscles, infiltrating trapezius, rhomboid, subscapularis, and latissimus dorsi. The patient underwent en bloc tumor excision, including paraspinal muscles and partial vertebral elements, followed by immediate reconstruction using regional rotational musculocutaneous flaps (latissimus dorsi and trapezius) performed by a combined oncologic and reconstructive surgical team. Postoperative recovery was uneventful, and the patient was discharged with preserved functional mobility and no wound complications. MPL is recognized for its high recurrence rate and poor survival. Complete surgical resection remains the cornerstone of treatment, particularly when neoadjuvant therapy is not feasible or ineffective. Reconstruction of large posterior trunk defects is technically demanding due to limited tissue elasticity and the scarcity of recipient vessels for free flaps. Regional pedicled options, including trapezius, latissimus dorsi, and paraspinous flaps, remain reliable strategies. This case emphasizes the feasibility of achieving both oncologic clearance and functional coverage in elderly patients with extensive defects. This case highlights the rarity of MPL in advanced age and posterior trunk location, underscoring the critical role of individualized reconstructive planning. Regional pedicled flaps provide safe and effective coverage, ensuring functional preservation and reduced morbidity following radical resection.

#3

Pleomorphic liposarcoma of the breast.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia2026

Primary sarcomas of the breast are exceptionally rare, accounting for fewer than 1% of malignant breast lesions. Mammary liposarcomas comprise less than 5% of all breast sarcomas, and among these, primary pleomorphic liposarcoma is particularly uncommon, with a reported frequency of less than 0.01% of malignant breast lesions. It is a highly aggressive tumour, characterised by a high recurrence rate. The characteristic microscopic findings of pleomorphic liposarcoma include atypical lipomatous cells with marked nuclear pleomorphism, as well as abundant lipoblasts, frequent mitoses, and extensive areas of necrosis. In this article, we present a case of primary pleomorphic liposarcoma of the breast.

#4

Synchronous Retroperitoneal Pleomorphic Liposarcoma and Colonic Mucinous Adenocarcinoma.

Case reports in oncology2026

Multiple primary malignancies (MPM), defined as two or more distinct primary tumors in 1 patient, are uncommon, with synchronous presentations (diagnosed within 6 months) being rarer. The coexistence of retroperitoneal liposarcoma and a synchronous gastrointestinal malignancy, particularly colorectal adenocarcinoma, is an exceptionally rare clinical entity, posing significant diagnostic and therapeutic challenges. A 63-year-old male presented with fatigue, anorexia, and weight loss. The initial workup revealed microcytic anemia and positive fecal occult blood. While initial endoscopic biopsies were inconclusive, a contrast-enhanced CT scan identified two distinct masses: a large (20 cm) heterogeneous retroperitoneal mass suggestive of liposarcoma and a thickened right colic flexure. The patient underwent a combined en bloc surgical resection, including an extended right hemicolectomy and resection of the retroperitoneal mass with the right kidney. Histopathology confirmed two high-grade primary malignancies: a retroperitoneal pleomorphic liposarcoma (stage IIIb) and a colonic mucinous adenocarcinoma (stage pT3 pN2b). Adjuvant chemotherapy (CAPOX regimen) was initiated for high-risk colon cancer. This case highlights the necessity of a high index of suspicion for synchronous malignancies in patients with non-specific constitutional symptoms. Comprehensive cross-sectional imaging is crucial for accurate staging. Management requires a multidisciplinary approach to plan complex surgical interventions and tailor adjuvant therapy, often prioritizing the more aggressive or higher stage malignancy. This report underscores the complexity of MPM and the need for individualized patient care.

#5

Myxoid Pleomorphic Liposarcoma: A Review and Update.

Cancer genomics & proteomics2026

Myxoid pleomorphic liposarcoma (MPLPS) is an exceedingly rare and recently recognized adipocytic neoplasm that primarily occurs in children and young adults and shows a strong predilection for the mediastinum. Clinically, MPLPS demonstrates aggressive behavior and exhibits a high propensity for systemic spread and a worse overall survival. Some cases have been associated with Li-Fraumeni syndrome. Histologically, MPLPS is composed of a variable mixture of myxoid and pleomorphic liposarcoma-like components. Immunohistochemically, the tumor cells show diffuse expression of CD34 and p16 and loss of nuclear RB expression. MPLPS lacks DNA damage inducible transcript 3 (DDIT3) rearrangements and MDM2 proto-oncogene (MDM2) amplifications but shows tumor protein p53 (TP53) mutations and RB transcriptional co-repressor 1 (RB1) deletions. Moreover, recent studies have demonstrated that the most consistent molecular feature of MPLPS is genome-wide loss of heterozygosity. Surgical excision with negative margins is the mainstay of treatment for localized MPLPS. The treatment of advanced/metastatic MPLPS still poses a huge therapeutic challenge. This review provides information about the clinicoradiological features, pathogenesis, histopathology, and management currently available for MPLPS. In addition, we discuss the differential diagnosis of this novel entity.

Publicações recentes

Myxoid Pleomorphic Liposarcoma Imitating Recurrent Traumatic Hemopericardium.

JACC Case Rep2026 Mar 19

Surgical Strategies for Closure of Complex Posterior Trunk Defects in Myxoid Pleomorphic Liposarcoma: A Case Report and Literature Review.

Cureus2026 Feb

Pleomorphic liposarcoma of the breast.

Rev Esp Patol2026 Jan-Mar

Synchronous Retroperitoneal Pleomorphic Liposarcoma and Colonic Mucinous Adenocarcinoma.

Case Rep Oncol2026 Jan-Dec

Myxoid Pleomorphic Liposarcoma: A Review and Update.

Cancer Genomics Proteomics2026 Jan-Feb

Ver todas no PubMed

📚 EuropePMC199 artigos no totalmostrando 198

Myxoid Pleomorphic Liposarcoma Imitating Recurrent Traumatic Hemopericardium.

JACC. Case reports

Surgical Strategies for Closure of Complex Posterior Trunk Defects in Myxoid Pleomorphic Liposarcoma: A Case Report and Literature Review.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

Pleomorphic liposarcoma of the breast.

Synchronous Retroperitoneal Pleomorphic Liposarcoma and Colonic Mucinous Adenocarcinoma.

Case reports in oncology

Cancer genomics & proteomics

Myxoid Pleomorphic Liposarcoma: A Review and Update.

High Immunohistochemical Expression of SETD5 as a Candidate Pathological Factor for Dedifferentiation and Prognosis in Liposarcoma.

Pathology international

Eribulin and sintilimab combined with radiotherapy in a heavily pretreated patient with advanced retroperitoneal myxoid pleomorphic liposarcoma: a case report and literature review.

Central European journal of urology

Paratesticular liposarcomas: A rare but crucial diagnosis. Case series and review of literature.

medRxiv : the preprint server for health sciences

Distinct Sarcoma Microenvironments Predict Benefit from Addition of Pembrolizumab to Preoperative Radiotherapy and Surgery in SU2C-SARC032.

American journal of translational research

Prognostic factors in retroperitoneal liposarcoma after R0 resection: a study of age, histologic type, tumor stage, and differentiation grade.

Journal for immunotherapy of cancer

Priming the tumor microenvironment with pembrolizumab and radiotherapy for durable cures in high-risk localized undifferentiated pleomorphic sarcoma and pleomorphic/dedifferentiated liposarcoma.

Histomorphological and molecular characteristics of liposarcoma (Review).

Oncology letters

Pancreatic liposarcoma: A case series and literature overview of an extremely rare soft tissue tumor.

Nuclear medicine and molecular imaging

18F-FAPI-04 PET/CT Imaging of Rare Brain Metastasis from Myxoid Pleomorphic Liposarcoma.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Prognostic Implications of MDM2 and CDK4 Co-amplification in Liposarcoma: Insights from FISH analysis for Translational Oncology.

Intrathoracic Extrapulmonary Pleomorphic Liposarcoma: A Rare Presentation.

Journal of surgical oncology

Incomplete Cancer Surgery Correlates With Loss of Immune Surveillance and Hyper-Progression of Disease.

Journal of surgical oncology

Temporospatial Recurrence Patterns and Predictive Factors for Recurrences in 984 Patients With Adult Soft Tissue Sarcomas.

MS-stable/TMB-high pleomorphic liposarcoma successfully treated with pembrolizumab: a case report.

European journal of case reports in internal medicine

Rapid Paralysis and Hidden Malignancy: Acute Motor Axonal Neuropathy Revealing Pleomorphic Liposarcoma.

Clinicopathological and molecular diagnostic features of liposarcoma: A study of 27 cases.

CytoJournal

An asymptomatic flesh-colored tumor on the dorsal hand.

JAAD case reports

Beyond the benign: A rare case report of myxoid pleomorphic liposarcoma.

Primary pleomorphic liposarcoma involving bilateral ovaries: Case report and literature review.

Open life sciences

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

Vulvar Cellular Angiofibroma With Cytologic Atypia and Sarcomatous Transformation: A Clinicopathologic Analysis.

Redefining radiologic responses in high-risk soft-tissue sarcomas treated with neoadjuvant chemotherapy: final results of ISG-STS 1001, a randomized clinical trial.

ESMO open

Medical journal, Armed Forces India

Primary intracerebral pleomorphic liposarcoma in a young male.

Survival and prognostic factors among different types of liposarcomas based on SEER database.

Scientific reports

Upper Extremity Dedifferentiated Liposarcoma With an Osseus Component: An Uncommon Pathology.

Annals of surgical oncology

Sarcoma: Last Year's Practice Changing Papers.

Phenotypic plasticity in parotid tumours: insights from a surgical oncologist's perspective.

BMJ case reports

Liposarcoma: A Journey into a Rare Tumor's Epidemiology, Diagnosis, Pathophysiology, and Limitations of Current Therapies.

Cancers

Safety and efficacy of pembrolizumab, radiation therapy, and surgery versus radiation therapy and surgery for stage III soft tissue sarcoma of the extremity (SU2C-SARC032): an open-label, randomised clinical trial.

Lancet (London, England)

Journal of neurosurgery. Case lessons

Intracranial pleomorphic liposarcoma misclassified as a pleomorphic xanthoastrocytoma by a DNA methylation classifier: illustrative case.

Strategies in Surgical Salvage: Navigating a Chest Wall Sarcoma Emergency.

Recurrent Intrathoracic Liposarcoma: A Case Report and a Comprehensive Literature Review of a Rare Clinical Entity.

Advances in anatomic pathology

Lipomatous Neoplasms of Soft Tissue: A Contemporary Review.

Atypical Spindle Cell/Pleomorphic Lipomatous Tumor: A Review and Update.

Cancers

Journal of surgical oncology

Pleomorphic Liposarcoma of the Extremity and Trunk: Multimodality Therapy for Some but Not All?

Novel MEN1-associated retroperitoneal pleomorphic liposarcoma.

Rare tumors

The diagnosis, genetic alternation, and treatment of the primary pleomorphic liposarcoma of the femur in a rare age: Case report and literature review.

Heliyon

Lipoleiomyosarcoma with pleomorphic liposarcoma of the uterus: Computed tomography findings with pathological correlation. A case report and review of literature.

Case reports in oncological medicine

Successful Preoperative Radiotherapy for Neglected Shoulder Liposarcoma: A Retrospective Case Report.

Myxoid Pleomorphic Liposarcoma of the Spermatic Cord: A Rare Entity at a Rare Site.

Pleomorphic Liposarcoma Cytologically Detected in Hemosiderotic Pleural Effusion: Pitfalls Mitigated by Cytologic Clues and Cellblock Immunocytochemistry.

Diagnostic cytopathology

The American Journal of dermatopathology

Superficial Atypical Lipomatous Tumor With Pleomorphic Features: Case Report and Discussion of the Literature.

Primary pleomorphic liposarcoma of the cecum case report.

Medicina (Kaunas, Lithuania)

Pleomorphic Liposarcoma Unraveled: Investigating Histopathological and Immunohistochemical Markers for Tailored Diagnosis and Therapeutic Innovations.

Analysis of MDM2 and TP53 genes in canine liposarcoma.

Scientific reports

Radiation‑induced pleomorphic liposarcoma after hypofractionated radiotherapy following breast‑conserving surgery: A case report and literature review.

Oncology letters

Genes, chromosomes & cancer

Genomic profiling of pleomorphic rhabdomyosarcoma reveals a genomic signature distinct from that of embryonal rhabdomyosarcoma.

Journal of molecular histology

An overview on liposarcoma subtypes: Genetic alterations and recent advances in therapeutic strategies.

Surgical pathology clinics

Sarcoma of the Lung and Mediastinum.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

Primary hepatic pleomorphic liposarcoma: Case report and literature review.

Zhonghua wai ke za zhi [Chinese journal of surgery]

[Advances in the etiology of retroperitoneal liposarcoma].

Histology and histopathology

Myxoid pleomorphic liposarcoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Atypical Spindle Cell/Pleomorphic Lipomatous Tumor With Sarcomatous Transformation: Clinicopathologic and Molecular Analysis of 4 Cases.

International journal of surgical pathology

A Case of Myxoid Pleomorphic Liposarcoma with Rhabdoid Cells: A Diagnostic Pitfall.

Zhonghua bing li xue za zhi = Chinese journal of pathology

[Well-differentiated/dedifferentiated liposarcoma associated with myxoid-like morphology: a clinicopathological and molecular genetic characteristics analysis of 34 cases].

Genetic, Epigenetic and Transcriptome Alterations in Liposarcoma for Target Therapy Selection.

Cancers

Diffuse intra-abdominal sarcomatosis in myxoid pleomorphic liposarcoma.

BMJ case reports

Acquired isolated factor VII deficiency in a patient with myxoid pleomorphic liposarcoma, case report.

Neoplasia (New York, N.Y.)

Genetically engineered mouse model of pleomorphic liposarcoma: Immunophenotyping and histologic characterization.

Metastatic Epithelioid Pleomorphic Liposarcoma in the Brain: A Case Report.

Journal of clinical pathology

Rare myxoid pleomorphic liposarcoma: a case report and literature review.

An extremely rare case of recurrent pleomorphic myxoidliposarcoma with response to eribulin chemotherapy - A case report.

Rare tumors

Well-differentiated liposarcoma of tongue: A case report.

Clinical case reports

Journal of medical case reports

Pleomorphic liposarcoma of the extremity with solitary huge liver metastasis at initial diagnosis treated with conversion surgery combined with adjuvant chemotherapy: a case report.

[Large excoriated pleomorphic liposarcoma].

Revue medicale de Liege

A Para-Scrotal Pleomorphic Liposarcoma Mimicking As Another Scrotum (Pseudo-Scrotum): A Case Report.

Current treatment options in oncology

Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review.

European journal of breast health

Primary Breast Pleomorphic Liposarcoma Evaluation With MRI and Pathology: A Rare Case.

Virchows Archiv : an international journal of pathology

Myxoid liposarcoma with nuclear pleomorphism: a clinicopathological and molecular study.

Myxoid pleomorphic liposarcoma of the orbit: intratumoural genetic similarities and heterogeneity.

Pathology

Primary pleomorphic liposarcoma of bone: A case report with literature review.

Diagnostics (Basel, Switzerland)

Initial Imaging Findings of Breast Liposarcoma: A Case Report.

Internal medicine (Tokyo, Japan)

Pleomorphic Liposarcoma Initially Presenting with Multiple Organ Involvement Including the Heart.

Virchows Archiv : an international journal of pathology

PRAME immunohistochemistry in soft tissue tumors and mimics: a study of 350 cases highlighting its imperfect specificity but potentially useful diagnostic applications.

Clinical and Pathological Features of Primary Orbital Liposarcoma in Chinese Patients.

Current eye research

Case reports in pathology

Rare Pleomorphic Liposarcoma Presented as Jejunal Obstruction.

Sultan Qaboos University medical journal

Giant Mediastinal Myxoid Pleomorphic Liposarcoma.

Photon and Proton irradiation in Patient-derived, Three-Dimensional Soft Tissue Sarcoma Models.

BMC cancer

Malignant adipocytic tumours: A 20‑year single‑centre retrospective study.

Oncology letters

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

[Clinical value of fluorescence in situ hybridization with MDM2 and DDIT3 probe in diagnosis of liposarcoma].

Case reports in pathology

A Case of GATA3 Positive Pleomorphic Liposarcoma, Epithelioid Variant: A Diagnostic Pitfall.

General thoracic and cardiovascular surgery cases

Primary pulmonary pleomorphic liposarcoma found with a massive hemothorax.

Journal of mid-life health

Pleomorphic Liposarcoma of Breast, Presenting as a Recurrent Breast Tumor.

Fluorodeoxyglucose positron emission tomography (FDG/PET) shows the effect of carbon-ion radiotherapy (CIRT); with pathologic confirmation.

Case report: Pathological complete response to perioperative treatment of radiotherapy combined with angiogenesis inhibitor in a patient with pleomorphic liposarcoma.

Ear, nose, & throat journal

Pleomorphic Liposarcoma of the Parapharyngeal Space: A Rare Case Report.

Primary pleomorphic liposarcoma of the pancreas: A case report.

Asian journal of surgery

Journal of surgical case reports

Myxoid pleomorphic liposarcoma of the falciform ligament: a rare case report.

Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li-Fraumeni syndrome and the novel detection of c-myc amplification: a case report.

Diagnostic pathology

Establishment and characterization of NCC-PLPS2-C1: a novel cell line of pleomorphic liposarcoma.

Human cell

Histopathological Features of Myxoid Pleomorphic Liposarcoma in an African Pygmy Hedgehog (Atelerix Albiventris).

Veterinary sciences

A "V"-Shaped Intraoral Lipoma on the Floor of the Mouth: A Case Report.

Myxoid pleomorphic liposarcoma in the teres minor muscle: A case report.

A case report of 2 distinct primary sarcomas arising in an extremity in rapid succession.

Revista espanola de patologia : publicacion oficial de la Sociedad Espanola de Anatomia Patologica y de la Sociedad Espanola de Citologia

[Pleomorphic liposarcoma arising in an unusual site. A case report].

Primary intrathoracic liposarcomas: A clinicopathologic and molecular study of 43 cases in one of the largest medical centers of China.

Pleomorphic Liposarcoma: A Series of 120 Cases With Emphasis on Morphologic Variants.

Giant pulmonary pleomorphic liposarcoma: A case report and literature review.

Asian journal of surgery

Zhonghua bing li xue za zhi = Chinese journal of pathology

[Myxiod pleomorphic liposarcoma: a clinicopathological and molecular genetic analysis of six cases].

Pleomorphic Liposarcoma Revisited.

Orthopedics

Current opinion in oncology

New molecular entities of soft tissue and bone tumors.

Superficial CD34-Positive Fibroblastic Tumor: A Clinicopathologic, Immunohistochemical, and Molecular Study of 59 Cases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Myxoid pleomorphic liposarcoma is distinguished from other liposarcomas by widespread loss of heterozygosity and significantly worse overall survival: a genomic and clinicopathologic study.

Zhonghua nan ke xue = National journal of andrology

[Myxoid liposarcoma of the testis: A case report and review of the literature].

Oncology research and treatment

Established and Experimental Systemic Treatment Options for Advanced Liposarcoma.

Pleomorphic liposarcoma: A clinicopathologic study of 20 FNA cases.

Cancer cytopathology

Case reports in orthopedics

Pleomorphic Liposarcoma of Femur: A Rare Soft Tissue Sarcoma Metastasized to the Bone-Case Report and Review of Literature.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements.

American journal of ophthalmology case reports

Primary orbital pleomorphic liposarcoma in a child: A case report.

Journal of Ayub Medical College, Abbottabad : JAMC

Diagnostic Utility Of Fish For MDM2 In Adipocytic Neoplasms.

Mediastinum (Hong Kong, China)

Sarcomas of the mediastinum with epithelioid morphology.

Nanoparticle albumin-bound paclitaxel and PD-1 inhibitor (sintilimab) combination therapy for soft tissue sarcoma: a retrospective study.

BMC cancer

Rare Case of Primary Pulmonary Pleomorphic Liposarcoma Treated With Multimodal Therapy.

Ochsner journal

Zhonghua bing li xue za zhi = Chinese journal of pathology

[Paratesticular liposarcoma: the clinicopathological features of nineteen cases].

Epithelioid Variant of Pleomorphic Liposarcoma: A Rare Challenging Diagnosis Causing Severe Medial Thigh Pain.

Primary pleomorphic liposarcoma of the liver: a case report and literature review.

Surgical case reports

World journal of hepatology

Indeterminate liver lesions on gadoxetic acid-enhanced magnetic resonance imaging of the liver: Case-based radiologic-pathologic review.

Pleomorphic liposarcoma with liver metastasis diagnosed by combined fine-needle aspiration cytology and core-needle biopsy.

Diagnostic cytopathology

A rare case of myxoid pleomorphic liposarcoma in an infant: A report.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

Surgical Challenges in a Case of a Recurrent Giant Pleomorphic Liposarcoma of Neck And Mediastinum in a Child: A Rare Occurrence.

Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research.

Sarcoma

Circulation. Cardiovascular imaging

Dramatic Presentation of Cardiac Pleomorphic Liposarcoma.

Journal of the National Comprehensive Cancer Network : JNCCN

Larotrectinib in a Patient With Advanced Pleomorphic Liposarcoma of the Uterus.

Fat-Finding Mission: Primary Pleomorphic Liposarcoma of the Heart and Pericardium.

JACC. Case reports

Pleomorphic liposarcoma of the male breast: lessons from a rare malignancy during COVID-19 pandemic.

BMJ case reports

Annals of translational medicine

Turning 'Cold' tumors 'Hot': immunotherapies in sarcoma.

American journal of cancer research

Inhibition of P53-mediated cell cycle control as the determinant in dedifferentiated liposarcomas development.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Myxoid pleomorphic liposarcoma-a clinicopathologic, immunohistochemical, molecular genetic and epigenetic study of 12 cases, suggesting a possible relationship with conventional pleomorphic liposarcoma.

Pathology, research and practice

Molecular characterization of pleomorphic liposarcomatous differentiation in malignant phyllodes tumor of the breast: A case report.

A Case of Phyllodes Tumor of the Breast with Mixed Liposarcoma: Case Report and Literature Review.

OncoTargets and therapy

Journal of Nepal Health Research Council

Rare Case of Metastatic Pleomorphic Liposarcoma of Thigh Presenting as Ewing's Sarcoma.

Cancer immunology, immunotherapy : CII

Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas.

Diagnostics (Basel, Switzerland)

The Rapidly Expanding Group of RB1-Deleted Soft Tissue Tumors: An Updated Review.

Atypical Pleomorphic Lipomatous Tumor: Expanding Our Current Understanding in a Clinicopathologic Analysis of 64 Cases.

Virchows Archiv : an international journal of pathology

Liposarcoma in children and young adults: a clinicopathologic and molecular study of 23 cases in one of the largest institutions of China.

Journal of orthopaedic surgery and research

Survivorship and prognostic factors for pleomorphic liposarcoma: a population-based study.

Recent advances in the understanding and management of liposarcoma.

Faculty reviews

Contrast media & molecular imaging

Prediction of Histologic Subtype and FNCLCC Grade by SUVmax Measured on 18F-FDG PET/CT in Patients with Retroperitoneal Liposarcoma.

The rare primary bone sarcomas: imaging-pathological correlation.

Skeletal radiology

Establishment and characterization of NCC-PLPS1-C1, a novel patient-derived cell line of pleomorphic liposarcoma.

Human cell

Gastroenterologia y hepatologia

Primary lesser sac pleomorphic liposarcoma mimicking gastric GIST.

Recurrent Primary Pleomorphic Liposarcoma of the Breast: A Case Report with Imaging Findings.

Journal of breast cancer

Journal of the American Society of Cytopathology

Cytopathology of myxofibrosarcoma: a study of 66 cases and literature review.

Mediastinum (Hong Kong, China)

Liposarcomas of the mediastinum.

Cardiovascular diagnosis and therapy

Mediastinal liposarcoma masquerading as penetrating aortic ulcer in the descending aorta: a case report.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Broadening the spectrum of NTRK rearranged mesenchymal tumors and usefulness of pan-TRK immunohistochemistry for identification of NTRK fusions.

DDIT3 Immunohistochemistry Is a Useful Tool for the Diagnosis of Myxoid Liposarcoma.

Mediastinum (Hong Kong, China)

Mediastinal sarcomas: experience using fine needle aspiration cytopathology.

American journal of clinical pathology

A Reappraisal of Superficial Pleomorphic Liposarcoma.

Tumor-associated macrophages and macrophage-related immune checkpoint expression in sarcomas.

Oncoimmunology

Zentralblatt fur Chirurgie

[Systemic Therapy Options for Locally Advanced and Metastatic Myxoid, Dedifferentiated and Pleomorphic Liposarcoma].

Ocular oncology and pathology

Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Myxoid Stroma in a Hereditary Retinoblastoma Survivor.

Journal of cancer research and clinical oncology

Primary anatomical site as a prognostic factor for pleomorphic liposarcoma.

Dermatology online journal

Toxic epidermal necrolysis after radiotherapy for pleomorphic liposarcoma.

Current opinion in otolaryngology & head and neck surgery

From head and neck lipoma to liposarcoma: a wide spectrum of differential diagnoses and their therapeutic implications.

Indian journal of surgical oncology

Pleomorphic Liposarcoma of Finger-a Rare Entity.

International journal of surgical pathology

Recurrent Pleomorphic Myxoid Liposarcoma in a Patient With Li-Fraumeni Syndrome.

Virchows Archiv : an international journal of pathology

What's new in adipocytic neoplasia?

Medical archives (Sarajevo, Bosnia and Herzegovina)

Dedifferentiated Liposarcoma of the Left Thigh: a Rare Case.

Cerebral pleomorphic liposarcoma: Clinicopathologic findings.

Clinical neuropathology

European journal of radiology

Abnormal vascularization of soft-tissue sarcomas on conventional MRI: Diagnostic and prognostic values.

Lipomatous Tumors in Pediatric Patients: A Retrospective Analysis of 50 cases.

Turk patoloji dergisi

Journal of cutaneous pathology

An atypical pleomorphic lipomatous tumor arising on the cheek.

Ultrasound in medicine & biology

Sonographic Appearances of Liposarcoma: Correlations with Pathologic Subtypes.

Oncology research and treatment

Retrospective Analysis of Patients with Advanced Liposarcoma in a Tertiary Referral Center.

Clinical sarcoma research

Immunophenotypic expression of UCP1 in hibernoma and other adipose/non adipose soft tissue tumours.

Molecular medicine reports

CBX3 predicts an unfavorable prognosis and promotes tumorigenesis in osteosarcoma.

Medical sciences (Basel, Switzerland)

Real-World Experiences with Pazopanib in Patients with Advanced Soft Tissue and Bone Sarcoma in Northern California.

Seminars in diagnostic pathology

A contemporary review of myxoid adipocytic tumors.

Seminars in diagnostic pathology

Pleomorphic liposarcoma: Updates and current differential diagnosis.

Asian cardiovascular & thoracic annals

Pleomorphic liposarcoma of chest wall: a rare entity with challenging management.

Translational gastroenterology and hepatology

Histology driven systemic therapy of liposarcoma-ready for prime time?

PRDM10-rearranged Soft Tissue Tumor: A Clinicopathologic Study of 9 Cases.

Case Report: presentation of pleomorphic liposarcoma arising in a borderline phyllodes tumor.

Annals of diagnostic pathology

Subclassification of pleomorphic sarcomas: How and why should we care?

Atypical spindle cell/pleomorphic lipomatous tumor: A clinicopathologic, immunohistochemical, and molecular study of 20 cases.

Pathology international

Free latissimus dorsi musculocutaneous flap for external hemipelvectomy reconstruction.

Microsurgery

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model.

BMC cancer

Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model.

Tissue & cell

Journal of cellular biochemistry

Tumor-targeting Salmonella typhimurium A1-R arrests a doxorubicin-resistant PDGFRA-amplified patient-derived orthotopic xenograft mouse model of pleomorphic liposarcoma.

Pathobiology : journal of immunopathology, molecular and cellular biology

Metaplastic Breast Cancer Masquerading as Liposarcoma of the Breast: A Case Report following Oncoplastic Treatment.

[Clinical experience in diagnosis and treatment of primary retroperitoneal liposarcoma].

Zhonghua yi xue za zhi

Hellenic journal of nuclear medicine

Simultaneous pulmonary and inferior vena cava tumor thromboembolism secondary to retroperitoneal pleomorphic liposarcoma.

Pleomorphic liposarcoma: An analysis of 6 case reports and literature review.

Clinical sarcoma research

Pleomorphic liposarcoma of bone: a rare primary malignant bone tumour.

Open medicine (Warsaw, Poland)

Primary Pleomorphic Liposarcoma of Fallopian Tube with Recurrence: A Case Report and Review of the Literature.

Amplification of FRS2 in atypical lipomatous tumour/well-differentiated liposarcoma and de-differentiated liposarcoma: a clinicopathological and genetic study of 146 cases.

Histopathology

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical and Molecular Spectrum of Liposarcoma.

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

[One case report of pleomorphic liposarcoma of larynx].

Programmed Death Ligand 1 (PD-L1) Expression in Malignant Mesenchymal Tumors.

Turk patoloji dergisi

Effective apatinib treatment of pleomorphic liposarcoma: A case report.

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

A huge primary pleomorphic liposarcoma of the left atrium.

PD-1 and PD-L1 expression in bone and soft tissue sarcomas.

Pathology

Zhongguo fei ai za zhi = Chinese journal of lung cancer

[Relapsed Pleomorphic Liposarcoma with Mediastinal Metastasis: A Case Report  and Review of the Literature].

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Próxima:Associações

Associações

Organizações que acompanham esta doença — pra ter apoio e orientação

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Doença com base genética

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Conselhos e sociedades

Próxima:Doenças relacionadas

Doenças relacionadas

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Ordenadas pelo número de sintomas em comum.

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ORPHA:3394

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Lipossarcoma

Síndrome do hamartoma PTEN

ORPHA:69078

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Vasculite secundária

Deficiência de adesão leucocitária tipo III

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Síndromes mielodisplásicos

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ORPHA:52688

Fasceíte eosinofílica

Síndrome óculo-cerebro-renal de Lowe

ORPHA:3165

Vasculite associada a anticorpos anti-neutrófilo citoplasmáticos (ANCA)

ORPHA:534

Vasculite mediada por complexos imunes

ORPHA:156152