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Pneumopatia criptogênica organizada
ORPHA:1302CID-10 · J84.1CID-11 · CB03.2DOENÇA RARA

A pneumonia em organização criptogênica (COP) é ​​uma forma de pneumonia intersticial idiopática caracterizada patologicamente por pneumonia em organização (PO) que se apresenta com sintomas inespecíficos semelhantes aos da gripe, além de tosse e dispneia e onde nenhum agente etiológico é encontrado.

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Introdução

O que você precisa saber de cara

📋

A pneumonia em organização criptogênica (COP) é ​​uma forma de pneumonia intersticial idiopática caracterizada patologicamente por pneumonia em organização (PO) que se apresenta com sintomas inespecíficos semelhantes aos da gripe, além de tosse e dispneia e onde nenhum agente etiológico é encontrado.

Publicações científicas
545 artigos
Último publicado: 2026 Mar 19

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
Unknown
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Worldwide
Início
Adolescent
+ adult, childhood, elderly
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: J84.1
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Entender a doença

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🫁
Pulmão
8 sintomas
🩸
Sangue
2 sintomas
📏
Crescimento
2 sintomas

+ 17 sintomas em outras categorias

Características mais comuns

90%prev.
Consolidação parenquimatosa
Muito frequente (99-80%)
90%prev.
Tosse
Muito frequente (99-80%)
55%prev.
Neutrofilia
Frequente (79-30%)
55%prev.
Dispneia
Frequente (79-30%)
55%prev.
Opacificação em vidro fosco na TC de alta resolução pulmonar
Frequente (79-30%)
55%prev.
Fadiga
Frequente (79-30%)
29sintomas
Muito frequente (2)
Frequente (11)
Ocasional (8)
Muito raro (6)
Sem dados (2)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 29 características clínicas mais associadas, ordenadas por frequência.

Consolidação parenquimatosaParenchymal consolidation
Muito frequente (99-80%)90%
TosseCough
Muito frequente (99-80%)90%
NeutrofiliaNeutrophilia
Frequente (79-30%)55%
DispneiaDyspnea
Frequente (79-30%)55%
Opacificação em vidro fosco na TC de alta resolução pulmonarGround-glass opacification on pulmonary HRCT
Frequente (79-30%)55%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico545PubMed
Últimos 10 anos200publicações
Pico202147 papers
Linha do tempo
2026Hoje · 2026🧪 2006Primeiro ensaio clínico📈 2021Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

🧬

Nenhum gene associado encontrado

Os dados genéticos desta condição ainda estão sendo catalogados.

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
2Fase 22
·Pré-clínico1
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 3 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Pneumopatia criptogênica organizada

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

3 ensaios clínicos encontrados.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
293 papers (10 anos)
#1

Acute fibrinous and organizing pneumonia after bone marrow transplantation, an underrecognized, severe condition.

Hematology, transfusion and cell therapy2026 Jan 10

Allogeneic bone marrow transplantation can lead to various pulmonary complications, including acute fibrinous organizing pneumonia. This condition is rare and presents with aggressive clinical features, distinct from other forms of organizing pneumonia, such as cryptogenic organizing pneumonia. A literature review using the PubMed, Embase, Lilacs, and Cochrane databases was conducted to analyze cases of acute fibrinous organizing pneumonia following transplantation focusing on clinical features, therapeutic approaches, and outcomes. The case of a 62-year-old female who developed acute fibrinous organizing pneumonia after transplantation for acute myeloid leukemia is presented. Despite an initial absence of infectious agents, parainfluenza virus was later identified in a bronchoalveolar lavage. The patient progressed to severe hypoxemic respiratory failure and was unresponsive to corticosteroids and rituximab, ultimately dying seven months post-transplant. This is a rare and severe complication following allogeneic bone marrow transplantation. Early diagnosis, histopathological confirmation, and prompt initiation of corticosteroid therapy are critical for improving outcomes. Patients diagnosed before Day +100 generally have a better response to treatment and more favorable clinical outcomes. The need for a more effective and targeted treatment strategy remains an unmet challenge in managing this condition.

#2

Pulmonary Complications Following Hematopoietic Cell Transplantation in Patients with Myelofibrosis: A Single-Center Retrospective Cohort Analysis.

Transplantation and cellular therapy2026 Mar

Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder that frequently results in extramedullary hematopoiesis. Hematopoietic cell transplantation (HCT) is the only cure. While a 2-fold increase in pneumonia and respiratory-related mortality was recently reported in MF patients compared to the general population, the incidence and etiology of HCT-related pulmonary complications have not been well studied. We performed a retrospective chart review of consecutive MF patients who underwent HCT between 2002 and 2022. Patients with evidence of pulmonary impairment on pulmonary function tests, defined as a ≥10-point decline in forced expiratory volume in 1 second (FEV1) compared to pre-HCT and/or a decline in the FEV1/forced vital capacity (FVC) ratio to <0.7, received further chart review to determine the etiology of this decline. Of 228 patients evaluated, 126 (55%) met either the FEV1 or FEV1/FVC criteria for pulmonary impairment. After further chart review, 35 patients (15.4%) were diagnosed with broncholitis obliterans (BOS) by a pulmonologist or graft-versus-host disease specialist. Other common causes of impairment included respiratory infections (n =10), cryptogenic organizing pneumonia (n = 8), and deconditioning (n = 8). MF patients have a >50% likelihood of developing pulmonary impairment following HCT and a higher-than-expected incidence of BOS. This study supports increased pulmonary monitoring post-HCT in patients with MF.

#3

When Positron Emission Tomography (PET) Is Misleading: Ion™ Robotic Bronchoscopy Identifies Organizing Pneumonia and Unmasks a Rare Pulmonary Granular Cell Tumor.

Cureus2026 Feb

Pulmonary nodules with increased metabolic activity on positron emission tomography (PET) are frequently presumed malignant; however, inflammatory and rare benign neoplastic processes may produce false-positive findings. A 61-year-old African American male with a history of calcified and non-calcified pulmonary nodules and severe emphysema was referred to our pulmonary nodule clinic from the emergency department after a newly discovered lung nodule was identified on computed tomography (CT) of the chest. Subsequent evaluation demonstrated metabolic activity on PET, raising concern for malignancy; however, tissue diagnosis revealed organizing pneumonia. This case highlights diagnostic pitfalls associated with commonly used imaging and biomarker modalities in the evaluation of pulmonary nodules and emphasizes the importance of clinical awareness of a rare tumor, granular cell tumor (GCT), among physicians who may be unfamiliar with or have never encountered this condition.

#4

Organizing Pneumonia Phenotype.

Seminars in roentgenology2026 Jan

Organizing pneumonia (OP) is a nonspecific lung parenchymal response to any form of injury, with its idiopathic variant coined as cryptogenic organizing pneumonia (COP). The hallmark pathological features are presence of polypoid granulation tissue, or Masson bodies, in the alveolar spaces, with lung architecture preserved in most patients with good clinical outcomes poststeroid treatment. Clinically, patients exhibit signs and symptoms of subclinical or subacute infection that do not respond to antibiotics. Computed Tomography (CT) plays a vital role in establishing the diagnosis, monitoring of OP, and for better understanding of its imaging phenotypes which are crucial for clinical decision making. This article highlights the 3 main imaging patterns of OP on CT, the classic, nodular and fibrotic forms. Identifying these diverse imaging features holds the key for precise diagnosis of OP.

#5

Incidence of malignancy in lung lesions initially classified as organizing pneumonia on CT-guided biopsies.

Abdominal radiology (New York)2026 Jan

Organizing pneumonia is an inflammatory disorder that may co-exist with malignancy in the lung or elsewhere in the body. We aimed to assess patients with a lung biopsy diagnosis of organizing pneumonia for subsequent pathology confirmation of co-existing malignancy. In this retrospective IRB-approved, HIPAA-compliant study, 1314 consecutive patients who underwent CT-guided lung biopsy for suspected lung cancer or metastatic disease from 02/2014 to 04/2022 at a single tertiary referral hospital were identified. In 98/1314 (7.5%) patients, biopsies showed organizing pneumonia, which represented our study cohort. Clinical outcomes, including follow-up imaging and repeat tissue sampling if performed, were evaluated through chart review. Descriptive statistics were calculated. There were 43/98 (44%) females, mean age was 66 ± 14 years, mean lesion size 2.9 ± 2.1 cm, and 11/98 (11.2%) had prior history of malignancy. Of 98 patients initially diagnosed with organizing pneumonia on lung biopsy, 11 (11.2%) were subsequently found to have malignancy. Among these, 6 (54.5%) had pulmonary metastases and 5 (45.5%) had primary lung cancer. Malignancies were confirmed through percutaneous re-biopsy in 3/11 (27%) and bronchoscopic, endoscopic, or surgical procedures in 8/11 (73%). Malignancy can co-exist with organizing pneumonia in a substantial percentage of initial lung biopsies. Therefore, repeat tissue sampling should be considered when there is high clinical suspicion of malignancy despite an initial histopathological diagnosis of organizing pneumonia. This is especially relevant in lesions that demonstrate FDG avidity on PET/CT or an increase in size on interval imaging, or in instances where the biopsy core sizes are small or where the biopsies have intraprocedural complications.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC206 artigos no totalmostrando 197

2026

The Epidemiology of Cryptogenic Organizing Pneumonia: An Analysis of Data from The Nationwide Inpatient Sample.

Chest
2026

When Positron Emission Tomography (PET) Is Misleading: Ion™ Robotic Bronchoscopy Identifies Organizing Pneumonia and Unmasks a Rare Pulmonary Granular Cell Tumor.

Cureus
2026

Acute fibrinous and organizing pneumonia after bone marrow transplantation, an underrecognized, severe condition.

Hematology, transfusion and cell therapy
2026

Organizing Pneumonia Phenotype.

Seminars in roentgenology
2025

GATA2 deficiency presenting with Hodgkin's lymphoma and cryptogenic organizing pneumonia: a case report of two siblings.

Frontiers in medicine
2025

Role of Systemic Inflammatory Markers in the Differential Diagnosis of Organizing Pneumonia and Lung Cancer.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
2026

Pulmonary Complications Following Hematopoietic Cell Transplantation in Patients with Myelofibrosis: A Single-Center Retrospective Cohort Analysis.

Transplantation and cellular therapy
2025

Chemotherapy for Breast Cancer with Pre-existing Cryptogenic Organizing Pneumonia: Epirubicin/cyclophosphamide Followed by Weekly Paclitaxel.

The Keio journal of medicine
2025

A Rare Case of Pediatric Pulmonary Sarcoidosis Without Lymph Node Involvement Presenting With Centrilobular Ground-Glass Opacities.

Cureus
2025

Diagnostic value of "River Sign" in focal organizing pneumonia.

Medicine
2025

Acute fibrinous and organizing pneumonia presents as right lung upper lobe cavitary lesion: Case report and literature review.

Medicine
2025

Safety assessment of gemtuzumab ozogamicin: real-world adverse event analysis based on the FDA Adverse Event Reporting System.

Frontiers in medicine
2025

Cryptogenic Organizing Pneumonia.

Seminars in respiratory and critical care medicine
2025

Cryptogenic Organizing Pneumonia: A Case Report.

The Journal of the Association of Physicians of India
2025

Perioperative Treatment of Metachronous Multiple Lung Cancer with Organizing Pneumonia: A Case Report.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
2025

Pulmonary metastasis of chondrosarcoma diagnosed by transbronchial lung biopsy after differentiation from organizing pneumonia: A case report.

Respiratory investigation
2025

[Reversed halo sign as imaging manifestation of primary Sjögren's syndrome with nonspecific interstitial pneumonia].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
2025

Navigating Complexity in Pediatric NMOSD: Unusual Symptoms and Adverse Reactions: A Case Report.

Reports (MDPI)
2025

Reversed halo sign on chest computed tomography: a retrospective analysis of 286 cases.

Radiologia brasileira
2025

Impending myxedema as a manifestation of subclinical hypothyroidism in a case of systemic lupus erythematosus: A case report.

Medicine
2025

Pulmonary MALT lymphoma diagnosed with transbronchial lung cryobiopsy after unsuccessful transbronchial lung biopsy: a case report.

Frontiers in medicine
2025

Bilateral Pleural Effusion in Cryptogenic Organizing Pneumonia: A Case Report and Review of Atypical Presentations.

Cureus
2025

Reversed halo sign: from a clinico-radiologic-pathologic point of view.

European journal of medical research
2026

Incidence of malignancy in lung lesions initially classified as organizing pneumonia on CT-guided biopsies.

Abdominal radiology (New York)
2025

Quantitative analysis of pathological findings identified clinical heterogeneity in nonspecific interstitial pneumonia with organising pneumonia overlap.

Scientific reports
2025

Ten Questions on Using Lung Ultrasonography to Diagnose and Manage Pneumonia in Hospital-at-Home Model: Part II-Confounders and Mimickers.

Diagnostics (Basel, Switzerland)
2025

Cryptogenic organizing pneumonia complicated by pulmonary embolism following glucocorticoid therapy: a case report.

BMC pulmonary medicine
2025

Influence of content-based image retrieval on the accuracy and inter-reader agreement of usual interstitial pneumonia CT pattern classification.

European radiology
2025

Psittacosis pneumonia with the reversed halo sign: a case report and literature review.

BMC infectious diseases
2025

Diagnostic Utility of Bronchoalveolar Lavage Flow Cytometric Leukocyte Profiling in Interstitial Lung Disease and Infection.

Biomolecules
2025

Acute fibrinous and organising pneumonia presenting with mass-like imaging: a case report.

Diagnostic pathology
2025

Diffuse pulmonary ossification and its association with cicatricial organising pneumonia in idiopathic and secondary forms.

Scientific reports
2025

Reversed halo sign in cryptogenic organizing pneumonia.

QJM : monthly journal of the Association of Physicians
2025

Korean Guidelines for Diagnosis and Management of Interstitial Lung Disease: Cryptogenic Organizing Pneumonia.

Tuberculosis and respiratory diseases
2024

Lung involvement in patients with psoriatic arthritis.

Archives of rheumatology
2024

[Organizing Pneumonia: Analysis of 10 Years Registers in a Chilean Center].

Revista medica de Chile
2025

Primary pulmonary diffuse large B cell lymphoma presenting with features of organizing pneumonia: a case report.

Journal of medical case reports
2025

Epidemiologic Survey for Work-Related Idiopathic Interstitial Pneumonias Focusing on Idiopathic Pulmonary Fibrosis in Korea, 2010-2022.

Journal of occupational and environmental medicine
2025

Magnetic resonance imaging of focal organizing pneumonia: differential diagnosis with peripheral lung carcinoma.

Acta radiologica (Stockholm, Sweden : 1987)
2025

Immunophenotyping of T Cells in Lung Malignancies and Cryptogenic Organizing Pneumonia.

Journal of clinical medicine
2025

Chronic pulmonary silicone embolism after breast implant rupture: an underdiagnosed cause of acute fibrinous and organizing pneumonia?

BMJ case reports
2025

Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study.

Respiratory research
2025

Concomitant Pulmonary and Biliary Manifestations of Ulcerative Colitis: A Case Report.

Clinical case reports
2024

Secondary organizing pneumonia after infection.

World journal of clinical cases
2024

Disease Course, Treatment Response and Relapse in a Group of Patients with a Primary Diagnosis of Cryptogenic Organizing Pneumonia: A Cohort Study.

Tanaffos
2024

Invasive mucinous adenocarcinoma harbored MET exon 14 skipping mutation: case report.

Translational lung cancer research
2024

The Clinical Significance of Interstitial Pneumonia with Autoimmune Features in Cryptogenic Organizing Pneumonia: A Prospective Multicenter Observational Study.

Journal of clinical medicine
2024

[Bronchiolitis obliterans organizing pneumonia after radiotherapy: A systematic review and case report].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
2025

Ocrelizumab-associated cryptogenic organizing pneumonia in multiple sclerosis: Two case reports and comprehensive literature review.

Multiple sclerosis (Houndmills, Basingstoke, England)
2024

TB or Not TB, That is the Question?

British journal of hospital medicine (London, England : 2005)
2024

Organising pneumonia due to inadequately cleared COVID-19 infection while on rituximab.

BMJ case reports
2024

Cryptogenic Organizing Pneumonia Is Associated With Increased Mortality Risk in Hospitalizations for Systemic Lupus Erythematosus (SLE): A National Inpatient Sample Analysis.

Cureus
2024

Computed tomography patterns and clinical outcomes of radiation pneumonitis in non-small-cell lung cancer patients.

Acta radiologica open
2024

Cryptogenic organizing pneumonia caused by solanine: A case report.

Medicine
2024

Organizing pneumonia associated with Richter transformation in chronic lymphocytic leukemia: a case report and review of the literature.

Folia medica Cracoviensia
2025

Lepidic Pulmonary Metastasis from Pancreatic Carcinoma Mimicking Organizing Pneumonia, Diagnosed by a Transbronchial Cryobiopsy.

Internal medicine (Tokyo, Japan)
2025

Identification of novel TTN gene variant in a patient exhibiting severe dilated cardiomyopathy co-occurring with acute fibrinoid organizing pneumonia.

American journal of clinical pathology
2024

Pulmonary manifestation of VEXAS syndrome.

BMJ case reports
2024

Bronchiolitis Obliterans Organizing Pneumonia After Breast Radiation Therapy.

Practical radiation oncology
2024

Rituximab Therapy for Immune-Mediated Neurological Diseases: Our Experience at a Tertiary Care Centre.

Cureus
2024

Late-Onset Noninfectious Pulmonary Complications After Allogeneic Hematopoietic Stem Cell Transplantation: Single-Center Experience.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
2024

Why do a lung biopsy for benign lesions?

Minerva surgery
2024

Application of Innovative 3D Pathological Tactic for Diagnosis of Organizing Pneumonia.

In vivo (Athens, Greece)
2024

Organizing Pneumonia Secondary to ASIA Syndrome.

Archivos de bronconeumologia
2024

Cryptogenic organizing pneumonia: clinical outcomes of 60 consecutive cases.

Journal of thoracic disease
2024

How I diagnose and treat organizing pneumonia in hematopoietic cell transplant recipients.

Blood
2024

TOM5 regulates the mitochondrial membrane potential of alveolar epithelial cells in organizing pneumonia.

Redox report : communications in free radical research
2024

A Case of Organizing Pneumonia Resembling Lung Cancer.

Clinical laboratory
2024

The degree of HLA matching determines the incidence of cytokine release syndrome and associated nonrelapse mortality in matched related and unrelated allogeneic stem cell transplantation with post-transplant cyclophosphamide.

Leukemia &amp; lymphoma
2024

Ultrasonic humidifier lung with a reversed halo sign: A case report.

Radiology case reports
2024

Relationship between idiopathic interstitial pneumonias (IIPs) and connective tissue disease-related interstitial lung disease (CTD-ILD): A narrative review.

Respiratory investigation
2024

Cyclosporine-Associated Organizing Pneumonia.

American journal of therapeutics
2023

Multimodality Appearances of Marginal Zone Lymphoma Masquerading as Cryptogenic Organizing Pneumonia-serial Chest Radiograph and High-resolution Computed Tomography Appearances: (18F) Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Staging Utility.

Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
2024

[Clinical analysis of 4 children with cryptogenic organizing pneumonia].

Zhonghua er ke za zhi = Chinese journal of pediatrics
2024

A case of late-onset organizing pneumonia following COVID-19 infection in a post-kidney transplant patient.

CEN case reports
2024

Cryptogenic organizing pneumonia after withdrawal of systemic corticosteroids for chronic eosinophilic pneumonia and severe asthma under benralizumab treatment.

Respiratory investigation
2024

Successful treatment of SARS-CoV-2 in an immunocompromised patient with persistent infection for 245 days: A case report.

Heliyon
2023

Organizing Pneumonia as a Pulmonary Sequela of Post-COVID-19 Syndrome in a Patient in Trinidad: A Case Report.

Cureus
2023

Trastuzumab Deruxtecan‒Related Interstitial Lung Disease/Pneumonitis: Computed Tomography Imaging Patterns to Guide Diagnosis and Management.

JCO precision oncology
2023

A Teaching Case: Persistent COVID-19 Pneumonia Resembling Cryptogenic Organizing Pneumonia in a Patient With Remitted Lymphoma.

Cureus
2023

Case report: Coexistence of triple-seronegative myasthenia gravis and pathology-proven cryptogenic organizing pneumonia.

Frontiers in neurology
2023

A case report: Acute fibrinous and organizing pneumonia.

Medicine
2024

Idiopathic Fibrotic Nonspecific Interstitial Pneumonia with Cicatricial Organizing Pneumonia and Intraluminal Pulmonary Ossification Containing Bone Marrow.

Internal medicine (Tokyo, Japan)
2023

Surgical Treatment of Secondary Pneumothorax-Complicated Interstitial Lung Disease.

Cureus
2024

Organizing Pneumonia in a Case of Cold Agglutinin Disease with Pulmonary Thrombosis.

Internal medicine (Tokyo, Japan)
2023

Clinical features of relapsed connective tissue disease-associated organizing pneumonia.

Respiratory medicine
2023

Good COP or bad COP: How much steroid is enough to avoid relapse?

Respiratory medicine
2023

Minocycline-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine
2023

A Case Report of Squamous Cell Carcinoma Misdiagnosed as Cryptogenic Organizing Pneumonia.

Cureus
2023

Minimal effective dose of maintenance steroid therapy for relapse of cryptogenic organizing pneumonia.

Respiratory medicine
2023

A case of acute severe cryptogenic organic pneumonia with secondary hemophilia.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
2023

Genetic Programs Between Steroid-Sensitive and Steroid-Insensitive Interstitial Lung Disease.

Inflammation
2023

Properties of Pleural Mesothelial Cells in Idiopathic Pulmonary Fibrosis and Cryptogenic Organizing Pneumonia.

Journal of Korean medical science
2023

Clinical Characteristics and Predictors of the Recurrence of Organizing Pneumonia Associated With Rheumatoid Arthritis.

The Journal of rheumatology
2023

Imaging Features of Idiopathic Interstitial Lung Diseases.

Journal of thoracic imaging
2023

Optical coherence tomography angiography characteristics of retinochoroidal and optic nerve head microcirculation in cryptogenic organizing pneumonia.

Photodiagnosis and photodynamic therapy
2023

Cryptogenic Organizing Pneumonia and Idiopathic Eosinophilic Pneumonia: A Case Report of Clinically Identical Entities.

Cureus
2023

Spontaneous resolution of cryptogenic organizing pneumonia: Observational study.

Medicine
2023

Resolution of an insidious and migratory Mycobacterium tuberculosis-associated secondary organizing pneumonia: a case report and literature review.

BMC infectious diseases
2023

An unexpected diagnosis of a 57-year-old women with migratory pulmonary infiltrates.

Respiratory medicine case reports
2023

Pulmonary tuberculosis associated acute fibrinous and organizing pneumonia: A case report and literature review.

The clinical respiratory journal
2023

Update on cryptogenic organizing pneumonia.

Frontiers in medicine
2023

Endothelial Injury Syndromes after Allogeneic Hematopoietic Stem Cell Transplantation: Angiopetin-2 as a Novel Predictor of the Outcome and the Role of Functional Autoantibodies against Angiotensin II Type 1 and Endothelin A Receptor.

International journal of molecular sciences
2023

Transbronchial lung cr onchial lung cryobiopsy for the diagnosis of diffuse obiopsy for the diagnosis of diffuse parenchymal lung disease: Pitfalls and challenges, a single center experience.

Turkish journal of medical sciences
2023

Does cryptogenic organizing pneumonia change seasonal?

Revista da Associacao Medica Brasileira (1992)
2023

Cryptogenic organizing pneumonia in an infant.

Pediatric pulmonology
2023

Transbronchial cryobiopsy in unexplained, severe ARDS: a single center retrospective case series.

BMC pulmonary medicine
2022

Case Report: A Chlamydia psittaci pulmonary infection presenting with migratory infiltrates.

Frontiers in public health
2023

Association between early corticosteroid administration and long-term survival in non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation.

International journal of hematology
2023

Invasive aspergillosis mimicking cryptogenic organizing pneumonia in a patient with diffuse large B-cell lymphoma.

Polish archives of internal medicine
2022

Scrub typhus presenting as cryptogenic organizing pneumonia in a young female: A first case report.

Journal of family medicine and primary care
2022

Asymptomatic pulmonary cryptococcosis presenting with mixed lesions of infiltrative and nodular shadow in an immunocompromised patient.

BMJ case reports
2022

Case of organising pneumonia in HIV infection.

BMJ case reports
2022

Transient and Recurrent Pulmonary Infiltrations Associated with Familial Mediterranean Fever.

Internal medicine (Tokyo, Japan)
2022

Scoping review: The state of research on cryptogenic organizing pneumonia therapeutics.

Pulmonary pharmacology &amp; therapeutics
2022

Flecainide-induced pneumonitis: a case report.

Journal of medical case reports
2022

Rituximab for steroid-resistant organising pneumonia in a woman with rheumatoid arthritis.

BMJ case reports
2022

Chest CT Imaging Features of the Pulmonary Sequelae in Four Patients with COVID-19.

Taehan Yongsang Uihakhoe chi
2022

Post-COVID-19 sequelae of the respiratory system. A single-centre experience reporting the compromise of the airway, alveolar and vascular components.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
2022

Diagnostic value and safety of medical thoracoscopy under local anesthesia for unexplained diffuse interstitial lung disease: A retrospective study.

Chronic respiratory disease
2023

Cryptogenic organizing pneumonia: In the setting of Staphylococcus aureus endocarditis.

Pediatric pulmonology
2022

[Clinical characteristics of 6 children with idiopathic interstitial pneumonia].

Zhonghua er ke za zhi = Chinese journal of pediatrics
2022

IL-9 and IL-9 receptor expression in lymphocytes from bronchoalveolar lavage fluid of patients with interstitial lung disease.

Immunobiology
2023

Iatrogenic Adrenal Insufficiency Following Post COVID-19 Organizing Pneumonia.

Archivos de bronconeumologia
2022

Increased Interleukin-17 and Glucocorticoid Receptor-β Expression in Interstitial Lung Diseases and Corticosteroid Insensitivity.

Frontiers in immunology
2022

Cryptogenic Organizing Pneumonia Complicated With Cutaneous Disseminated Nocardia Infection: A Case Report and Literature Review.

Frontiers in medicine
2022

The many faces of cryptogenic organizing pneumonia (COP).

Journal of clinical imaging science
2022

Antisynthetase syndrome with rare EJ-1 antibodies with antiphospholipid syndrome.

Respirology case reports
2022

Cryptogenic Organizing Pneumonia: A Unique Case and Literature Review.

Cureus
2022

Comparison of Pulmonary Toxicity after Total Body Irradiation- and Busulfan-Based Myeloablative Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients.

Transplantation and cellular therapy
2022

A Case of Late-Onset Neuromyelitis Optica Spectrum Disorder Associated With Cryptogenic Organizing Pneumonia.

Clinical medicine insights. Case reports
2022

Organizing Pneumonia: A Clinical Challenge in a Child With Previous Rhabdomyosarcoma.

Journal of investigative medicine high impact case reports
2022

Case report: atrial septostomy as a bridge to lung transplantation in a patient with venovenous extracorporeal membrane oxygenation.

Medicine
2022

Cryptogenic organizing pneumonia associated with pregnancy: A case report.

World journal of clinical cases
2022

Noninfectious Pulmonary Toxicity after Allogeneic Hematopoietic Cell Transplantation.

Transplantation and cellular therapy
2022

Trimethoprim-sulfamethoxazole induced eosinophilic pneumonia: A case report.

Respiratory medicine case reports
2022

Neuromyelitis Optica Spectrum Disorder Associated with Cryptogenic Organizing Pneumonia in a Young Patient.

European journal of case reports in internal medicine
2022

Delayed-onset Organizing Pneumonia Emerging after Recovery from Coronavirus Disease 2019: A Report of Three Cases Diagnosed Using Transbronchial Cryobiopsy and a Review of the Literature.

Internal medicine (Tokyo, Japan)
2022

The evaluation of the association between the prevalence and patterns of computed tomography findings of cryptogenic organizing pneumonia, and neutrophil/lymphocyte and platelet/lymphocyte ratios.

Chinese journal of academic radiology
2021

Cryptogenic Organizing Pneumonia Secondary to Mycoplasma pneumoniae Infection: A Case Report.

Cureus
2022

Algorithmic Approach to the Diagnosis of Organizing Pneumonia: A Correlation of Clinical, Radiologic, and Pathologic Features.

Chest
2022

Demystifying idiopathic interstitial pneumonia: time for more etiology-focused nomenclature in interstitial lung disease.

Expert review of respiratory medicine
2022

Two cases of cryptogenic organizing pneumonia masquerading as tuberculosis (TB) in a TB endemic area.

Respirology case reports
2021

A Case Report of Steroid-Resistant Cryptogenic Organizing Pneumonia Managed with Intravenous Immunoglobulins.

Case reports in pulmonology
2022

[Aspergillus lentulus in a patient with cryptogenic organizing pneumonia treated with oral corticosteroids].

Open respiratory archives
2021

Organising pneumonia manifesting as a late-phase complication of COVID-19.

BMJ case reports
2021

Comparison of clinical features and prognosis in patients with cryptogenic and secondary organizing pneumonia.

BMC pulmonary medicine
2021

Disseminated Cryptococcus neoformans infection associated to COVID-19.

Medical mycology case reports
2022

Content-based Image Retrieval by Using Deep Learning for Interstitial Lung Disease Diagnosis with Chest CT.

Radiology
2021

Acute fibrinous and organizing pfneumonia: two case reports and literature review.

Diagnostic pathology
2022

Secondary organizing pneumonia after recovery of mild COVID-19 infection.

Journal of medical virology
2021

Crazy vaping and crazy-paving, a case of E-Cigarette/Vaping-Associated Lung Injury (EVALI) with chest CT showing crazy-paving pattern.

Radiology case reports
2021

Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players.

International journal of molecular sciences
2021

Cryptogenic organising pneumonia: current understanding of an enigmatic lung disease.

European respiratory review : an official journal of the European Respiratory Society
2021

Severe psittacosis progressing to suspected organizing pneumonia and the role of corticosteroids.

Respiratory medicine case reports
2021

The role of interleukin-6 as a prognostic biomarker for predicting acute exacerbation in interstitial lung diseases.

PloS one
2021

[Update 2021: Pulmonary Sequelae of COVID-19 Pneumonia].

Deutsche medizinische Wochenschrift (1946)
2021

Dyspnea in a 57-Year-Old Man With Recent Viral Illness.

Chest
2021

A Prospective Cohort Study Comparing Long-Term Outcomes with and without Palifermin in Patients Receiving Hematopoietic Cell Transplantation for Hematologic Malignancies.

Transplantation and cellular therapy
2021

Organizing pneumonia in ALK+ lung adenocarcinoma treated with ceritinib: A case report and literature review.

Medicine
2021

Amiodarone-induced organizing pneumonia mimicking COVID-19: a case report.

European journal of medical research
2021

Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia.

Tuberculosis and respiratory diseases
2021

Secondary organizing pneumonia following occupational acute nitrogen oxide poisoning: a case report.

The Journal of international medical research
2021

Integrated approach to bronchoalveolar lavage cytology to distinguish interstitial lung diseases.

European journal of internal medicine
2021

Epirubicin and Cyclophosphamide-induced Acute Fibrinous and Organizing Pneumonia.

American journal of respiratory and critical care medicine
2021

The clinicopathological analysis of organising pneumonia in myelodysplastic syndrome: high frequency in der(1;7)(q10; p10).

British journal of haematology
2021

Reversed halo sign in radiation induced organizing pneumonia: natural course of the underlying pathophysiology.

Pulmonology
2021

Comparison of Chest CT Findings of COVID-19, Influenza, and Organizing Pneumonia: A Multireader Study.

AJR. American journal of roentgenology
2021

Clinical features of acute fibrinous and organizing pneumonia: An early histologic pattern of various acute inflammatory lung diseases.

PloS one
2021

Diagnostic procedures and clinico-radiological findings of acute fibrinous and organizing pneumonia: a systematic review and pooled analysis.

European radiology
2021

Rapidly worsening pneumonia in a middle-aged woman: a rare diagnosis and a crucial management decision.

BMJ case reports
2021

Interstitial Lung Disease in Common Variable Immunodeficiency.

Frontiers in immunology
2021

Clinico-etiological characteristics of organizing pneumonia: A retrospective study.

Lung India : official organ of Indian Chest Society
2021

A 69-Year-Old Woman With Ulcerative Colitis and Pulmonary Nodules.

Chest
2021

A rare cause of secondary organising pneumonia.

BMJ case reports
2021

Obliterans With Organizing Pneumonia: A Possible Misdiagnosis of Lung Graft-Versus-Host Disease in Posttransplant Patients With COVID-19.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
2021

Organizing pneumonia as a manifestation of coronavirus disease 2019.

Pathology international
2021

[Cryptogenic organizing pneumonia versus secondary organizing pneumonia].

Der Pathologe
2021

Cryptogenic organising pneumonia: an unusual cause of pleuritic chest pain.

BMJ case reports
2021

Diagnostic yield, safety, and impact of transbronchial lung biopsy in mechanically ventilated, critically ill patients: a retrospective study.

BMC pulmonary medicine
2021

Disease-modifying antirheumatic drugs and organising pneumonia.

BMJ case reports
2021

A 65-year-old Woman With Persistent Dyspnea, Arthritis, and Raynaud's Phenomenon.

The American journal of the medical sciences
2021

Case of Severe Treatment-Resistant Cryptogenic Organizing Pneumonia.

Acta medica Lituanica
2021

Wandering Pneumonia Mimicked by COVID-19.

Internal medicine (Tokyo, Japan)
2020

Cellular analysis of bronchoalveolar lavage fluid to narrow differential diagnosis of checkpoint inhibitor-related pneumonitis in metastatic melanoma.

Journal of translational medicine
2021

COVID-19 mimics on chest CT: a pictorial review and radiologic guide.

The British journal of radiology
2021

Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region.

Archives of pathology &amp; laboratory medicine
2021

A Duck after Treatment for Extensive Organizing Pneumonia.

Internal medicine (Tokyo, Japan)
2021

Content-Based Image Retrieval of Chest CT with Convolutional Neural Network for Diffuse Interstitial Lung Disease: Performance Assessment in Three Major Idiopathic Interstitial Pneumonias.

Korean journal of radiology
2021

Bronchiolitis obliterans organizing pneumonia as the pulmonary manifestation of lupus: A review of three cases.

Lupus
2022

Effectiveness of Steroid Treatment for SARS-CoV-2 Pneumonia With Cryptogenic Organizing Pneumonia-Like Reaction: A Case Report.

Disaster medicine and public health preparedness
2021

Radiographic features and poor prognostic factors of interstitial lung disease with nivolumab for non-small cell lung cancer.

Cancer science
2020

Granulomatosis with polyangiitis complicated with refractory optic neuritis and maxillary osteomyelitis.

Modern rheumatology case reports
2021

Tuberculosis heralding connective tissue disorder.

Tropical doctor
2020

Obstructive sleep apnea in patients with interstitial lung disease: Prevalence and predictive factors.

PloS one
2020

Idiopathic focal organizing pneumonia mimicking malignancy.

The Pan African medical journal
2021

Cryptogenic organizing pneumonia by alectinib.

Medicina clinica
Ver todos os 206 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Acute fibrinous and organizing pneumonia after bone marrow transplantation, an underrecognized, severe condition.
    Hematology, transfusion and cell therapy· 2026· PMID 41520509mais citado
  2. Pulmonary Complications Following Hematopoietic Cell Transplantation in Patients with Myelofibrosis: A Single-Center Retrospective Cohort Analysis.
    Transplantation and cellular therapy· 2026· PMID 41207385mais citado
  3. When Positron Emission Tomography (PET) Is Misleading: Ion&#x2122; Robotic Bronchoscopy Identifies Organizing Pneumonia and Unmasks a Rare Pulmonary Granular Cell Tumor.
    Cureus· 2026· PMID 41664670mais citado
  4. Organizing Pneumonia Phenotype.
    Seminars in roentgenology· 2026· PMID 41513514mais citado
  5. Incidence of malignancy in lung lesions initially classified as organizing pneumonia on CT-guided biopsies.
    Abdominal radiology (New York)· 2026· PMID 40504392mais citado
  6. Pulmonary Complications of Cancer Therapy: Clinical Presentations, Imaging Patterns, and Management Strategies.
    Medicina (Kaunas)· 2026· PMID 41901659recente
  7. The Epidemiology of Cryptogenic Organizing Pneumonia: An Analysis of Data From the Nationwide Inpatient Sample.
    Chest· 2026· PMID 41812990recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:1302(Orphanet)
  2. MONDO:0015264(MONDO)
  3. GARD:1620(GARD (NIH))
  4. Busca completa no PubMed(PubMed)
  5. Q2012642(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Pneumopatia criptogênica organizada
Compêndio · Raras BR

Pneumopatia criptogênica organizada

ORPHA:1302 · MONDO:0015264
Prevalência
Unknown
Herança
Not applicable
CID-10
J84.1 · Outras doenças pulmonares intersticiais com fibrose
CID-11
Início
Adolescent, Adult, Childhood, Elderly
Prevalência
0.0 (Worldwide)
MedGen
UMLS
C0242770
Repurposing
47 candidatos
atovaquonemitochondrial electron transport inhibitor
azithromycinbacterial 50S ribosomal subunit inhibitor
benzylpenicillinpenicillin binding protein inhibitor
+17 outros
EuropePMC
Wikidata
Papers 10a
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