The impact of the expression signatures of LncRNAs HBBP1 and XIST on the diagnostic significance of patients with β-Thalassemia.

Unraveling the link: Beta-thalassemia intermedia and Moyamoya syndrome-a hidden connection.

Hemoglobin Dieppe (HBB:c. 383A > G): A Rare Dominant β-Thalassemia in an Iraqi Kurdish Family.

Novel HBB:c.375_376delAC mutation in a Malay patient with HbE beta-thalassemia intermedia: A case report.

Erythroid activity modulates iron regulation in pathological erythropoiesis: A cross-sectional case-control study.

Magnitude of Beta-Hemoglobinopathies through Biomarkers among the Selected Tribes of Dharmapuri, Tamil Nadu: A Community-Based Cross-Sectional Study.

Predictors of Delayed Hemolytic Transfusion Reactions in Children With Beta-Thalassemia Intermedia: Insight From a Tunisian Reference-Center Analysis.

Therapeutic Response to Hydroxyurea in Beta-Thalassemia Intermedia with Rare Mutation: A Case Report.

Neurotherapy as a Complementary Approach for Beta-Thalassemia Intermedia.

Survey of Red Cell Transfusion Therapy and Immunohematology Services for Patients with Hemoglobinopathies in Türkiye.

Liver Function Parameters and Validation of Health-Related Quality of Life Assessment of β-Thalassemia Cases at a Tertiary Care Hospital, Lumbini Province, Nepal.

Effective non-surgical management of spinal cord compression from extra-medullary hematopoiesis with radiotherapy in thalassemia intermedia: a case report.

Application value of long-read sequencing in full characterization of thalassemia-associated structural variations: identifying a novel large segmental duplication and literature review.

Unusual Causes of β Thalassemia Trait: Discovery of another Three Novel SUPT5H Variants.

Pancreatic Volume in Thalassemia: Determinants and Association with Alterations of Glucose Metabolism.

Iron Overload-Related Oxidative Stress Leads to Hyperphosphorylation and Altered Anion Exchanger 1 (Band 3) Function in Erythrocytes from Subjects with β-Thalassemia Minor.

Hemolysis due to anti-IH in a patient with beta-thalassemia and Mycoplasma pneumoniae infection.

A case of intrathoracic extramedullary hematopoiesis-associated pleural effusion in a beta-thalassemia intermedia patient and a short literature review.

Serum lipid profile abnormalities among beta-thalassemia patients: a systematic review and meta-analysis.

Efficacy and safety of thalidomide in patients with β-thalassemia intermedia and major.

Health-Related Quality of Life of Adolescents With Non-transfusion-Dependent Thalassemia in Basrah, Iraq.

Acute disseminated encephalomyelitis (ADEM) in a patient with post streptococcal glomerulonephritis (PSGN): A case report.

Early Detection of Myocardial Involvement in Thalassemia Intermedia Patients: Multiparametric Mapping by Magnetic Resonance Imaging.

Integrated metabolomic and microbiome analysis identifies Cupriavidus metallidurans as a potential therapeutic target for β-thalassemia.

In vivo silencing of intestinal DMT1 mitigates iron loading in β-thalassemia intermedia (Hbbth3/+) mice.

Safety and efficacy of human apotransferrin infusion in patients with β-thalassemia intermedia: the AIM study.

Loss-of-Function Variants in SUPT5H as Modifying Factors in Beta-Thalassemia.

Characterization and Clinical Assessment of a Peculiar Case of Hemolytic Anemia.

Murine models of erythroid 5ALA synthesis disorders and their conditional synthetic lethal dependency on pyridoxine.

Mitoxantrone ameliorates ineffective erythropoiesis in a β-thalassemia intermedia mouse model.

Moderate-severe beta-thalassemia intermedia phenotype caused by sextuplicated alpha-globin gene allele in two beta-thalassemia carriers.

A Novel 165 Kb Duplication Involving the α-Globin Gene Cluster Is Identified by Low-Pass Whole Genome Sequencing in a Chinese Thalassemia Intermedia Patient.

Impact of genotype on multi-organ iron and complications in patients with non-transfusion-dependent β-thalassemia intermedia.

Unravelling the Complexity of the +33 C>G [HBB:c.-18C>G] Variant in Beta Thalassemia.

An update on recent studies of extracellular vesicles and their role in hypercoagulability in thalassemia (Review).

Suppression of Growth Differentiation Factor 15 Gene Expression by Curcumin in Patients with Beta-Thalassemia Intermedia.

Two novel deletion mutations in β-globin gene cause β-thalassemia trait in two Chinese families.

Phenotypic Clustering of Beta-Thalassemia Intermedia Patients Using Cardiovascular Magnetic Resonance.

Frequency of secondary modifiers in Beta Thalassemia intermedia in patients from Northern Punjab.

Transfusion requirements and complication rate in β-thalassemia intermedia due to heterozygous β-globin gene mutation and triplicated α-globin genes.

Clinical significance of mutational variants in beta and alpha genes in patients with hemoglobinopathies from two large Greek centers: a complex interplay between genotype and phenotype.

Rare Presentation of β-Thalassemia Intermedia With a Phenotype of Dilated Cardiomyopathy.

Epidemiology of clinically significant forms of alpha- and beta-thalassemia: A global map of evidence and gaps.

Dominant inherited β-thalassemia intermedia in a Polish family due to a novel frameshift mutation in HBB.

An Expert Overview on Therapies in Non-Transfusion-Dependent Thalassemia: Classical to Cutting Edge in Treatment.

Bone Mineral Density and Dickkopf-1 in Adolescents with Non-Deletional Hemoglobin H Disease.

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1: Preclinical Efficacy against Iron Overload and Safety Evaluation.

Mitapivat for sickle cell disease and thalassemia.

Differential proteomic patterns of plasma extracellular vesicles show potential to discriminate β-thalassemia subtypes.

β-thalassemia intermedia mimicking β-thalassemia trait: The importance of family studies and HBB genotyping in phenotypically ambiguous cases.

β-Thalassemia in childhood: Current state of health in a high-income country.

Protein C and S levels in patients with Thalassemia intermedia.

Investigation of the mechanism of copy number variations involving the α-globin gene cluster on chromosome 16: two case reports and literature review.

Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in β-thalassemia.

Non-Transfusion-Dependent Thalassemia: A Panoramic Review.

Renal Dysfunction in Pediatric Patients in Iraq With β-Thalassemia Major and Intermedia.

The hemoglobinopathies, molecular disease mechanisms and diagnostics.

β-Thalassemia Intermedia Caused by the β-Globin Gene 3' Untranslated Region: Another Case Report.

The Effect of Xmn -1 Polymorphism and Coinheritance of Alpha Mutations on Age at First Blood Transfusion in Iranian Patients with Homozygote IVSI-5 Mutation.

Impact of IFN-β1a in treatment of a COVID-19 patient with beta thalassemia and diabetes mellitus: A case report.

Intraoperative Cell-Saver Caused More Autologous Salvage Hemolysis in a Hereditary Spherocytosis Patient Than in a Normal Erythrocyte Patient.

Alpha-globin gene triplication and its effect in beta-thalassemia carrier, sickle cell trait, and healthy individual.

Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia.

Dual gradient echo in-phase and out of phase sequences in assessment of hepatic iron overload in patients with beta-thalassemia, would be better?

Bone mineral density in primarily preadolescent children with hemoglobin E/β-thalassemia with different severities and transfusion requirements.

Efficacy and Safety of Sinopharm Vaccine for SARS-CoV-2 and breakthrough infections in Iranian Patients with Hemoglobinopathies: A Preliminary Report.

β-Thalassemia Intermedia: Interaction of α-Globin Gene Triplication With β-thalassemia Heterozygous in Spain.

Iron overload status in patients with non-transfusion-dependent thalassemia in China.

Alpha- and Beta-thalassemia: Rapid Evidence Review.

The Effect of Curcumin on Iron Overload in Patients with Beta-Thalassemia Intermedia.

Therapeutic potential of silymarin as a natural iron-chelating agent in β-thalassemia intermedia.

Dominant β-Thalassemia Phenotype Caused by Hb Dieppe (HBB: c.383A>G): Another Case Report.

Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features.

Pitfalls in the Diagnosis of β-Thalassemia Intermedia.

Subclinical atherosclerotic predictive value of inflammatory markers in thalassemia intermedia patients.

Digital thermography and vascular involvement in β-thalassemia intermedia.

Beta-thalassemia intermedia with ischemic transients misdiagnosed as multiple sclerosis: A case report.

Modulatory effect of single nucleotide polymorphism in Xmn1, BCL11A and HBS1L-MYB loci on foetal haemoglobin levels in β-thalassemia major and Intermedia patients.

Development of the Quality of Life Questionnaire (SF-36) for Patients with β-Thalassemia Major and β-Thalassemia Intermedia Based on Extended Rasch Analysis.

Compound heterozygotes of Hb Constant Spring and Hb Stanleyville II in HbE/β0-thalassemia.

Spontaneous osteonecrosis of the jaw in a β-Thalassemia intermedia patient.

Oxidative status in the β-thalassemia syndromes in Sri Lanka; a cross-sectional survey.

Chronic Hemolysis May Adversely Affect Skeletal Health. A Cross-Sectional Study of a Pediatric Population.

A rare gene variation cap +1 (A>C) (HBB: c. -50A>C) associated with codon 5 (-CT) (HBB: c.17_18delCT) mutation in Syrian family.

Incidental Diagnosis of Adult Beta-Thalassemia With Point-of-Care Ultrasound in the Emergency Department: A Case Report.

The effect of curcumin on serum copper, zinc, and zinc/copper ratio in patients with β-thalassemia intermedia: a randomized double-blind clinical trial.

Prominent pseudo-Gaucher cells in a patient with β-thalassemia intermedia and plasma cell myeloma.

The relation between mitogen activated protein kinase (MAPK) pathway and different genes expression in patients with beta Thalassemia.

Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.

Evaluation of Adipokines Concentration in Iraqi Patients with Major and Minor Beta Thalassemia.

Acute lymphoblastic leukemia in a β-thalassemia intermedia child: A case report.

Phenotypical and functional abnormalities of circulating neutrophils in patients with β-thalassemia.

Corrigendum to "Beta-Thalassemia Intermedia: A Single Thalassemia Center Experience from Northeastern Iraq".

Preliminary Data on COVID-19 in Patients with Hemoglobinopathies: A Multicentre ICET-A Study.

Association of VDBP rs4701 Variant, but not VDR/RXR-α Over-Expression with Bone Mineral Density in Pediatric Well-Chelated β-Thalassemia Patients.

Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.

miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.

Assessment of Atherosclerosis in Peripheral and Central Circulation in Adult β Thalassemia Intermedia Patients by Color Doppler Ultrasound: Egyptian Experience.

Beta-Thalassemia Intermedia: A Single Thalassemia Center Experience from Northeastern Iraq.

Three Mexican Families with β thalassemia intermedia with different molecular basis.

Molecular epidemiology and hematologic characterization of δβ-thalassemia and hereditary persistence of fetal hemoglobin in 125,661 families of greater Guangzhou area, the metropolis of southern China.

Two Rare Pathogenic HBB Variants in a Patient with β-Thalassemia Intermedia.

Association between Different Polymorphic Markers and β-Thalassemia Intermedia in Central Iran.

Evaluation of endocrine complications in beta-thalassemia intermedia (β-TI): a cross-sectional multicenter study.

Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia.

A Novel εγδβ-Thalassemia Deletion Associated with Severe Anemia at Birth and a β-Thalassemia Intermedia Phenotype Later in Life in Three Generations of a Greek Family.

Evaluating viscoelastic properties and membrane electrical charges of red blood cells with optical tweezers and cationic quantum dots - applications to β-thalassemia intermedia hemoglobinopathy.

Oral ferroportin inhibitor VIT-2763: First-in-human, phase 1 study in healthy volunteers.

Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia.

Generation of an in vitro model of β-thalassemia using the CRISPR/Cas9 genome editing system.

Rare double heterozygosity for poly A(A〉 G) and CD17(A〉 T) of beta thalassemia intermedia in a Chinese family.

Heme-regulated eIF2α kinase in erythropoiesis and hemoglobinopathies.

A De Novo Heterozygous Variant (HBB: c.379delG, p.Val127Cysfs*32) Associated with a Mild β-Thalassemia Intermedia Phenotype in a Turkish Child.

Predictors of autoimmune hemolytic anemia in beta-thalassemia patients with underlying red blood cells autoantibodies.

Mahidol Scoring for Assessing Various Grades of β Thalassemia Intermedia.

Final Height and Endocrine Complications in Patients with β-Thalassemia Intermedia: Our Experience in Non-Transfused Versus Infrequently Transfused Patients and Correlations with Liver Iron Content.

A Case of Hereditary Spherocytosis Caused by a Novel Homozygous Mutation in the SPTB Gene Misdiagnosed as β-Thalassemia Intermedia Due to a KLF1 Gene Mutation.

Prevalence of abnormal glucose homeostasis in Chinese patients with non-transfusion-dependent thalassemia.

Activin-A is elevated in patients with thalassemia major and double heterozygous sickle cell/beta-thalassemia and correlates with markers of hemolysis and bone mineral density.

Role of Genomic Biomarkers in Increasing Fetal Hemoglobin Levels Upon Hydroxyurea Therapy and in β-Thalassemia Intermedia: A Validation Cohort Study.

Crosstalk between cytokine profile, redox, and iron status in β-Thalassemia: relation to frequency/duration of blood transfusion.

[Significance of Tissue Factor-Bearing Microparticle Procoagulation Activity and Antithrombin Ⅲ Detection in Thalassemia Patients].

The impact of illness perception and socio-clinico-demographic factors on perceived quality of life in children and adolescents with thalassemia intermedia.

Molecular characterization of β-thalassemia intermedia in the West Bank, Palestine.

Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia.

Hb Knossos (HBB: c.82G > T), β-globin CD 5 (-CT) (HBB: c.17_18delCT) and δ-globin CD 59 (-a) (HBD: c.179delA) mutations in a Syrian patient with β-thalassemia intermedia.

Krüppel-Like Factor 1 Gene Mutations in Thalassemia Patients from North Iran: Report of a New Mutation Associated with β-Thalassemia Intermedia.

Imbalance of erythropoiesis and iron metabolism in patients with thalassemia.

Vascular and hemostatic alterations associated with pulmonary hypertension in β-thalassemia hemoglobin E patients receiving regular transfusion and iron chelation.

Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia.

Validation of a patient-reported outcomes symptom measure for patients with nontransfusion-dependent thalassemia (NTDT-PRO© ).

Alterations of anticoagulant proteins and soluble endothelial protein C receptor in thalassemia patients of Chinese origin.

The survival rate of patients with beta-thalassemia major and intermedia and its trends in recent years in Iran.

Retrospective study of the incidence of portal vein thrombosis after splenectomy in hematological disorders: Risk factors and clinical presentation.

Compound Heterozygosity for Silent Cap +1570 (T>C) (HBB: c*96T>C), Codon 39 (C>T) (HBB: c.118C>T) and the Presence of αααanti-3.7/αα in Greece. A Case Presentation.

Efficacy and safety of resveratrol, an oral hemoglobin F-augmenting agent, in patients with beta-thalassemia intermedia.

First Report of β-Thalassemia Intermedia in a Patient Compound Heterozygous for -92 (C>T) and Codons 36/37 (-T) Mutations.

Deferoxamine-induced electronegative ERG responses.

Relationship of the Interaction Between Two Quantitative Trait Loci with γ-Globin Expression in β-Thalassemia Intermedia Patients.

Genotype-phenotype correlation among beta-thalassemia and beta-thalassemia/HbE disease in Thai children: predictable clinical spectrum using genotypic analysis.

Management of Children With β-Thalassemia Intermedia: Overview, Recent Advances, and Treatment Challenges.

Partial Splenectomy in the treatment of an adult with β thalassemia intermedia: A case report.

RNAi-mediated reduction of hepatic Tmprss6 diminishes anemia and secondary iron overload in a splenectomized mouse model of β-thalassemia intermedia.

Hepatocellular Carcinoma in a β-Thalassemia Intermedia Patient: Yet Another Case in the Expanding Epidemic.

Optimal Reference Gene Selection for Expression Studies in Human Reticulocytes.

Elevations of Thrombotic Biomarkers in Hemoglobin H Disease.

β-Thalassemia intermedia: a comprehensive overview and novel approaches.

A prospective analysis for prevalence of complications in Thai nontransfusion-dependent Hb E/β-thalassemia and α-thalassemia (Hb H disease).

Thalassemia Major and Intermedia in Patients Older than 35 Years: A Single Center Experience.

Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model.

Blood transfusion versus hydroxyurea in beta-thalassemia in Iran: a cost-effectiveness study.

Short-term administration of JAK2 inhibitors reduces splenomegaly in mouse models of β-thalassemia intermedia and major.

The Impact of Transfusion and Chelation on Oxidative Stress in Immigrant Syrian Children with β-Thalassemia.

Prevalence of low bone mass among adolescents with nontransfusion-dependent hemoglobin E/β-thalassemia and its relationship with anemia severity.

Comparison of Quality of Life in Patients with β-Thalassemia Intermedia and β-Thalassemia Major in Southern Iran.

Evaluation of the Clinical and Laboratory Characteristics of Previously Followed-up Thalassemia Intermedia Patients to Provide Them Better Care in the Future.

Thalassemia intermedia phenotype resulting from rare combination of c.46delT [Codon15 (-T)] mutation of beta globin gene and HPFH3.

Whole-exome sequencing identifies an α-globin cluster triplication resulting in increased clinical severity of β-thalassemia.

Red blood cells free α-haemoglobin pool: a biomarker to monitor the β-thalassemia intermedia variability. The ALPHAPOOL study.

Serum Hepcidin as a Diagnostic Marker of Severe Iron Overload in Beta-thalassemia Major.

Homozygous Mutation on the β-Globin Polyadenylation Signal in a Tunisian Patient with β-Thalassemia Intermedia and Coinheritance of Gilbert's Syndrome.

Revisiting beta thalassemia intermedia: past, present, and future prospects.

Papillary Fibroelastoma as a Cause of Cardiogenic Embolic Stroke in a β-Thalassemia Patient: Case Report and Literature Review.

Hydroxyurea for nontransfusion-dependent β-thalassemia: A systematic review and meta-analysis.

A Clinical Update of the Hb Siirt [β27(B9)Ala→Gly; HBB: c.83C>G] Hemoglobin Variant.

Combination of Hb Heze [β144(HC1)Lys→Arg; HBB: c.434A>G] and β0-Thalassemia in a Chinese Patient with β-Thalassemia Intermedia.

Genetic Variants at BCL11A and HBS1L-MYB loci Influence Hb F Levels in Chinese Zhuang β-Thalassemia Intermedia Patients.

Bone quality in beta-thalassemia intermedia: relationships with bone quantity and endocrine and hematologic variables.

Soluble fms-Like Tyrosine Kinase 1 as a Link Between Angiogenesis and Endothelial Dysfunction in Pediatric Patients With β-Thalassemia Intermedia.

Pregnancy in β-thalassemia intermedia at two tertiary care centers in Lebanon and Italy: A follow-up report on fetal and maternal outcomes.

Liver transplantation from a deceased donor with β-thalassemia intermedia is not contraindicated: A case report.

The association between four SNPs (rs7482144, rs4671393, rs28384513 and rs4895441) and fetal hemoglobin levels in Chinese Zhuang β-thalassemia intermedia patients.

Relationship Between Some Single-nucleotide Polymorphism and Response to Hydroxyurea Therapy in Iranian Patients With β-Thalassemia Intermedia.

Klf10 Gene, a Secondary Modifier and a Pharmacogenomic Biomarker of Hydroxyurea Treatment Among Patients With Hemoglobinopathies.

Excellent and durable response to radiotherapy in a rare case of spinal cord compression due to extra-medullary hematopoiesis in β-thalassemia intermedia: case report and clinicoradiological correlation.

EPO and hepcidin plasma concentrations in blood donors and β-thalassemia intermedia are not related to commercially tested plasma ERFE concentrations.

Clinical and biological specificity of beta-thalassemia intermedia: a case report.

First description of the rs45496295 polymorphism of the C/EBPE gene in β-thalassemia intermedia patients.

A Patient with β-Thalassemia Intermedia Secondary to Homozygosity for a Polyadenylation Signal Mutation (AATAAA > AATAGA) (HBB: C.*112A > G) on the β-Globin Gene.

A Comparison of Hemostatic Changes in Splenectomized and Nonsplenectomized β-Thalassemia Intermedia Patients.

Can mutations in the gene encoding transcription factor EKLF (Erythroid Krüppel-Like Factor) protect us against infectious and parasitic diseases?

A case report of extramedullary haematopoeisis in lumbosacral region presenting as cauda equina syndrome.

A comparison of heart function and arrhythmia in clinically asymptomatic patients with beta thalassemia intermedia and beta thalassemia major.

CLINICAL APPLICATION OF RECOMBINANT ERYTHROPOIETIN IN BETA-THALASSAEMIA INTERMEDIA.

Can hydroxyurea serve as a free radical scavenger and reduce iron overload in β-thalassemia patients?

Study of red blood cell alloimmunization risk factors in multiply transfused thalassemia patients: role in improving thalassemia transfusion practice in Fayoum, Egypt.

High incidence of silent cerebral infarcts in adult patients with beta thalassemia major.

Evaluation of bone mineral density in patients with hemoglobin H disease.

Evaluation of the Relationship Between Hb F Levels and Nucleated Red Blood Cells with Morbidity in Non Transfusion-Dependent Thalassemia Patients.

Molecular Characterization of β-Thalassemia Intermedia in Southeast Iran.

Cardiac and thrombotic complications in the peripartum period of a patient affected by beta-thalassemia intermedia: An unusual case.

Pulmonary hypertension associated with thalassemia syndromes.

Two novel copy number variations involving the α-globin gene cluster on chromosome 16 cause thalassemia in two Chinese families.

Risk factors for venous thromboembolism in adults with hemoglobin SC or Sβ(+) thalassemia genotypes.

[Screening and molecular diagnosis for a rare genotype of beta-thalassemia intermedia].

A Large Cohort Study of Genotype and Phenotype Correlations of Beta- Thalassemia in Iranian Population.

Real-life experience with liver iron concentration R2 MRI measurement in patients with hemoglobinopathies: baseline data from LICNET.

"Silent" β-thalassemia mutation (promoter nt-101 C > T) with increased hemoglobin A2.

Sensorineural hearing loss in β-thalassemia patients treated with iron chelation.