Ependimoma anaplásico é um tipo raro e agressivo de ependimoma que geralmente surge na parte superior do cérebro de crianças e adultos jovens, e que se manifesta com sintomas variados, incluindo dores de cabeça, náuseas, problemas de visão, perda de memória e dificuldade para andar.
Introdução
O que você precisa saber de cara
Ependimoma anaplásico é um tipo raro e agressivo de ependimoma que geralmente surge na parte superior do cérebro de crianças e adultos jovens, e que se manifesta com sintomas variados, incluindo dores de cabeça, náuseas, problemas de visão, perda de memória e dificuldade para andar.
Escala de raridade
<1/50kMuito rara
1/20kRara
1/10kPouco freq.
1/5kIncomum
1/2k
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 1 características clínicas mais associadas, ordenadas por frequência.
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Ependimoma anaplásico
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Publicações mais relevantes
Thoracic tanycytic ependymoma with anaplastic progression after subtotal resection and repeated radiotherapy: A 17-year follow-up case report.
Tanycytic ependymomas (TEs) are rare spindle-cell variants of spinal ependymomas. They are classified as central nervous system World Health Organization grade II, and they usually behave like ordinary spinal ependymomas especially following gross total resection (GTR). A 43-year-old male presented with a progressive paraparesis and sensory level at T4 (pain/ temperature loss). The magnetic resonance imaging showed an intradural intramedullary tumor extending from Th2 to Th5. Only a subtotal resection was performed as a central portion was tightly adherent to the spinal cord itself. Histology revealed a predominantly grade II TE; the main component showed a low proliferative index, whereas the anaplastic focus had a markedly elevated index. Despite craniospinal tomotherapy (36 Gy), tumor recurred 6 years 7 months later. Local tomotherapy was repeated 3 times (41.4, 40, and 30 Gy), but each treatment produced only transient shrinkage followed by regrowth at shorter intervals. Further irradiation was contraindicated due to cumulative dose constraints. Seventeen years after the first surgery, rapid enlargement over 3 months caused paraplegia and bladder-bowel dysfunction. Reoperation achieved GTR, and at this point the pathology showed a diffuse anaplastic ependymoma; the MR 6 months later showed no tumor recurrence. Although TE is usually indolent, it can harbor an anaplastic subclone and progress to malignancy after subtotal resection. Long-term surveillance and early reoperation when regrowth is first observed should be considered and is likely due to the development of anaplastic features.
Nivolumab-Associated Autoimmune Encephalopathy in a Child With Multiply Relapsed Anaplastic Ependymoma.
Recurrent pediatric posterior fossa anaplastic ependymoma managed with multiple resections: illustrative case.
Maximal safe resection of ependymoma should be attempted whenever feasible. To clarify the potential and limits of surgery in recurrent pediatric ependymoma, the authors report a posterior fossa anaplastic ependymoma in a boy who ultimately underwent 18 resections. After initial multimodal therapy, resection with no detectable contrast-enhancing tumor on imaging and/or no visually apparent residual tumor intraoperatively was achieved at each operation from the 5th through the 16th, yielding 8 years 8 months of surgery-only local control. At the 17th surgery, a small remnant invading the right dorsolateral medulla was unavoidable; 7 months later, an 18th procedure achieved only partial resection and was followed by reirradiation. Recurrences arose from varying ependymal sites along the floor of the fourth ventricle rather than a single fixed locus, and a normal-appearing ependymal lining re-formed after sequential resections. Across all 18 operations, no infectious complications occurred. The tumor later progressed to circumferential brainstem involvement, and the patient died of respiratory failure 16 years 8 months after initial therapy. Repeated resections achieving no radiographic and intraoperative residual tumor may contribute to long-term survival in ependymoma; however, durable survival appears to depend on the persistence of locally resectable relapse. https://thejns.org/doi/10.3171/CASE25834.
Clinical Features and Prognostic Indicators for Brainstem Ependymomas : A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.
Ependymomas is a rare brain tumor. Accumulative evidence has revealed that there are differences between pediatric and adult patients. However, the clinical features and survival prognosis of pediatric and adult patients with brainstem ependymomas remain unclear. Pediatric and adult patients with brainstem ependymomas diagnosed between 2000 and 2021 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The clinical characteristics (age, sex, race, tumor size treatment methods, etc.) of the included patients were reviewed, and the survival analysis was estimated via the Kaplan-Meier method. A total of 701 patients, including 269 pediatric patients and 432 adult patients, were identified. The median age of pediatric patients is 3.0 years old and the adult patients is 46.0 years old. Compared with adult brainstem ependymomas, pediatric patients showed a higher prevalence of anaplastic ependymoma, larger tumor size, and more frequent receipt of gross total resection (GTR), radiation, and chemotherapy (all P<0.001). Cox regression analysis identified that black race (P=0.032), and chemotherapy (P=0.048) are independent risk factors for pediatric brainstem ependymomas, and aging (P<0.001), male (P=0.034), and black race (P=0.002) for adult brainstem ependymomas. Survival analysis showed that GTR combined with radiation had significant overall survival advantage compared with other treatment regimens in both pediatric and adult cohorts (P=0.045 and P=0.034, respectively). This study comprehensively investigated the clinical features and survival outcomes of patients with brainstem ependymomas, and identified several independent prognostic variables. The best recommended treatment method was GTR combined with radiation.
Characteristics and therapeutic profile of the patients with upper cervical spinal cord ependymoma from the medulla oblongata to C4: A cohort of 108 cases.
Upper cervical spinal ependymomas (uCSE) is routinely identified as intramedullary ependymomas located from the oblongata medulla to C4 level. Our study aimed to report the outcomes and treatment profiles of uCSE from our cohort of uCSE patients. This retrospective observational study included 108 patients with upper cervical spinal ependymomas (uCSE) who underwent surgery at Huashan Hospital from 2008 to 2022. Demographic and clinical data were collected to identify risk factors may associated with post-operative spinal cord function, quality of life and respiratory function. The mean age of included patients was 44.30 ± 12.71 years old. The most common uCSE was ependymoma (103 of 108, 95.37 %), followed by subependymoma (3 of 108, 2.78 %) and anaplastic Ependymoma (2 of 108, 1.85 %). Age (P = 0.003), sex (P = 0.004), duration of symptoms (P = 0.010), pre-operative bladder functions (P = 0.012), post-operative pneumonia (P = 0.013) and Carbon Dioxide Retention (CDR) (P = 0.004) could independently correlate with Iiving quality of uCSE patients. Post-operative spinal cord function was associated with pneumonia immediately after operation (P = 0.017). In addition, post-operative pneumonia correlated with tumor location (P = 0.048), pre-operative McCormick scores (P = 0.008)/ motor functions (P = 0.022)/ NRS scores (P = 0.020), and tracheotomy immediately after operation (P < 0.001). Tracheotomy immediately after operation was associated with tumor location (P = 0.023), unsteady walking (P = 0.033), pre-operative NRS scores (P = 0.029), post-operative pneumonia (P < 0.001) and CDR (P < 0.001). Within uCSE patients, post-operative quality of life is associated with pre-operative spinal cord function and symptom duration, which emphasizing the importance of early intervention. Their post-operative respiratory dysfunctions also correlated with post-operative spinal cord function and quality of life.
Publicações recentes
Nivolumab-Associated Autoimmune Encephalopathy in a Child With Multiply Relapsed Anaplastic Ependymoma.
Thoracic tanycytic ependymoma with anaplastic progression after subtotal resection and repeated radiotherapy: A 17-year follow-up case report.
Recurrent pediatric posterior fossa anaplastic ependymoma managed with multiple resections: illustrative case.
Extraspinal sacrococcygeal anaplastic ependymoma: A case report.
Clinical Features and Prognostic Indicators for Brainstem Ependymomas : A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.
📚 EuropePMC159 artigos no totalmostrando 196
Nivolumab-Associated Autoimmune Encephalopathy in a Child With Multiply Relapsed Anaplastic Ependymoma.
Pediatric blood & cancerThoracic tanycytic ependymoma with anaplastic progression after subtotal resection and repeated radiotherapy: A 17-year follow-up case report.
Surgical neurology internationalRecurrent pediatric posterior fossa anaplastic ependymoma managed with multiple resections: illustrative case.
Journal of neurosurgery. Case lessonsExtraspinal sacrococcygeal anaplastic ependymoma: A case report.
International journal of surgery case reportsClinical Features and Prognostic Indicators for Brainstem Ependymomas : A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.
Journal of Korean Neurosurgical SocietyAscending Transtentorial Herniation: A Rare Complication of Posterior Cranial Fossa Tumors and Review of Literature.
Asian journal of neurosurgeryTargeted Therapy with Dalpiciclib in a Pediatric Patient with Anaplastic Ependymoma: A Case Study and Literature Review.
Recent patents on anti-cancer drug discoveryAn anaplastic ependymoma with chondroid metaplasia after stereotactic radiosurgery: illustrative case.
Journal of neurosurgery. Case lessonsCase Report: Clinical awareness about the effect of laser interstitial thermal therapy on pediatric high-grade brain tumors after radiotherapy.
Frontiers in surgeryCharacteristics and therapeutic profile of the patients with upper cervical spinal cord ependymoma from the medulla oblongata to C4: A cohort of 108 cases.
Clinical neurology and neurosurgeryPediatric skull base tumors: Clinical features and surgical outcomes; a single center retrospective study with a review of literature.
Brain & spineAnaplastic Ependymoma and Atypical Refractory Longitudinal Expansive Transverse Myelitis Due to Immune Reaction After COVID-19 - A Case Discussion That Raises Many Unknown Questions About Covid-19.
Noro psikiyatri arsiviAnaplastic cortical ependymoma in 10 months girl: A case report.
International journal of surgery case reportsTranscranial motor-evoked potentials disappear with pons transection.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryAdult supratentorial extraventricular anaplastic ependymoma with cerebrospinal fluid dissemination metastases: a case report.
Frontiers in neurologyImaging of Adult Malignant Soft Tissue Tumors of the Spinal Canal: A Guide for Spine Surgeons.
World neurosurgerySingle-cell RNA sequencing of anaplastic ependymoma and H3K27M-mutant diffuse midline glioma.
BMC neurologyStereotactic radiosurgery for the treatment of a distant recurrence of ependymoma on the optic nerve: illustrative case.
Journal of neurosurgery. Case lessonsA case of disseminated spinal astroblastoma harboring a MAMLD1::BEND2 fusion.
Neuropathology : official journal of the Japanese Society of NeuropathologyRecurrent intracranial anaplastic ependymoma with late-onset giant scalp metastasis.
Clinical case reportsC11orf95-RELA, YAP1-MAMLD1, and YAP1-FAM118B Fusion Negative Anaplastic Ependymoma with Lipogenic Differentiation.
Neurology IndiaSupratentorial extra-axial anaplastic ependymoma: a rare case report.
Annals of medicine and surgery (2012)Dorsal cervical approach for recurrent intradural anaplastic ependymoma.
Neurosurgical focus: Video[Ependymoma in WHO Classification of Tumours 5th Edition].
No shinkei geka. Neurological surgeryCombined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
The Lancet. OncologyDry Field Technique and Ultrasonic Aspirator in Endoscopic Removal of a Hemorrhagic Intraventricular Tumor in a 2-Year-Old Girl.
World neurosurgeryProstate-Specific Membrane Antigen (PSMA) Expression in The Neovasculature of High Grade Gliomas (Histopathological and Immunohistochemical Study).
Asian Pacific journal of cancer prevention : APJCPEfficacy of the pedicle trapezius muscle flap for the multisurgical removal of pediatric posterior fossa anaplastic ependymoma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryRecombinant polio-rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial.
The Lancet. Child & adolescent healthPrimary spinal anaplastic ependymoma: A single-institute retrospective cohort and systematic review.
Frontiers in oncologyHigh-grade neuroepithelial tumor with EP300::BCOR fusion and negative BCOR immunohistochemical expression: a case report.
Brain tumor pathologySpontaneous intracerebral haemorrhage secondary to 5-ALA-induced thrombocytopaenia in a paediatric patient: case report and literature review.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgerySupratentorial tumor resembling anaplastic ependymoma in an adolescent.
Brain pathology (Zurich, Switzerland)The Positive Impact of a Chemotherapeutic Approach on Relapse Ependymoma or WHO Grade III Anaplastic Ependymoma: Report of a Rare Case.
CureusA Nomogram for Prediction of Patients with Anaplastic Ependymoma in the Brain and Spinal Cord Survival.
Turkish neurosurgeryPhotodynamic therapy for malignant brain tumors in children and young adolescents.
Frontiers in oncologyA cystic anaplastic ependymoma mimicking a pilocytic astrocytoma.
Radiology case reportsPosterior Reversible Encephalopathy Syndrome Developing after Aggressive Posterior Fossa Tumor Surgery.
Asian journal of neurosurgeryUnusual Case of Multilevel Spinal Anaplastic Ependymoma.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiquesOligomicrodontia in a Pediatric Cancer Survivor after Chemotherapy: A Case Report.
Healthcare (Basel, Switzerland)Supratentorial extra-axial RELA fusion-positive ependymoma misdiagnosed as meningioma by intraoperative histological and cytological examinations: a case report.
Journal of medical case reportsExtra-Axial supratentorial anaplastic ependymoma: Unusual location of an aggressive tumor, A case report.
Indian journal of pathology & microbiologyMetronomic Cyclophosphamide With Cisplatin and Bevacizumab for Refractory Anaplastic Ependymoma: A Retrospective Study.
Anticancer researchManagement of intractable chronic cough during awake craniotomy: illustrative case.
Journal of neurosurgery. Case lessonsMagnetic Resonance Imaging of Unusual Neoplasms Related to Foramen of Luschka: A Review for Differential Diagnosis.
The Indian journal of radiology & imagingDiffusely infiltrating glioma with CREBBP-BCORL1 fusion showing overexpression of not only BCORL1 but BCOR: A case report.
Brain tumor pathologyEpidemiological characteristics of central nervous system tumors in children: a 5-year review of 3180 cases from Beijing Tiantan Hospital.
Chinese neurosurgical journalSupratentorial ependymoma, zinc finger translocation-associated fusion positive, with extensive synaptophysin immunoreactivity arising from malignant transformation of clear cell ependymoma: A case report.
Surgical neurology internationalClinical Profile and Outcomes of Primary Immunodeficiency and Malignancy in Childhood at a Tertiary Oncology Center in Developing Country.
Pediatric hematology and oncologyRefined Temporal-to-Frontal Horn Shunt for Treatment of Trapped Temporal Horn After Surgery of Peri- or Intraventricular Tumor: A Case Series Study.
Frontiers in oncologyAn Overview of Intracranial Ependymomas in Adults.
CancersAdult Posterior Fossa Anaplastic Ependymoma, Case Series and Literature Review.
World neurosurgeryWhat Happens after Therapy? Quality of Life and Neurocognitive Functions of Children with Malignant Posterior Fossa Tumors after Adjuvant Therapy.
Neurology IndiaClinical-pathological study of 28 glial and mixed neuronal-glial tumors diagnosed within the first year of life.
Clinical neuropathologySevere Pneumonia Caused by Methicillin-Resistant Staphylococcus pseudintermedius in an Oncology Patient: Case Report and Literature Review.
Microbial drug resistance (Larchmont, N.Y.)Bicentric Treatment Outcomes After Proton Therapy for Nonmyxopapillary High-Grade Spinal Cord Ependymoma in Children.
International journal of radiation oncology, biology, physicsExtra-Ventricular C11orf95-RELA Fusion Positive Anaplastic Ependymoma with Divergent Histological and Immunohistochemical Features: Report of a Rare Case.
Neurology IndiaPineal Anaplastic Ependymoma - A Rare Entity.
Neurology IndiaSupratentorial extraventricular ependymoma presenting calvarial erosion: A report of 3 cases.
Radiology case reportsCytology of Extraneural Metastases of Nonhematolymphoid Primary Central Nervous System Tumors: Six Cases with Histopathological Correlation and Literature Update.
Acta cytologicaAnaplastic myxopapillary ependymoma of the sacrum: A case report.
Surgical neurology internationalEpidemiology and Survival of Patients With Brainstem Gliomas: A Population-Based Study Using the SEER Database.
Frontiers in oncologyPAX6 is frequently expressed in ependymal tumours and associated with prognostic relevant subgroups.
Journal of clinical pathologyDifferential expression of stem cell markers in proliferating cells in glioma.
Journal of cancer research and clinical oncologyNimotuzumab therapy in the treatment of pediatric central nervous system tumors: single-center experience.
Naunyn-Schmiedeberg's archives of pharmacologyEpendymoma Presenting as a -Rim-Enhancing Lesion in the Brainstem.
Pediatric neurosurgeryImage-Guided Robotic Radiosurgery for the Management of Spinal Ependymomas.
Frontiers in oncologyDiffusion MRI in Evaluation of Pediatric Posterior Fossa Tumors.
Asian Pacific journal of cancer prevention : APJCPMediastinal Anaplastic Ependymoma.
Journal of chest surgeryThe Spectrum of Underlying Diseases in Children with Torticollis.
Turkish neurosurgeryHigh-grade neuroepithelial tumor with BCL6 corepressor-alteration presenting pathological and radiological calcification: A case report.
Pathology internationalRELA Fusion-Positive Ependymoma in a Child with Down Syndrome: A Case Report.
Pediatric neurosurgeryIntracranial ependymomas: The role of advanced neuroimaging in diagnosis and management.
The neuroradiology journalIntracytoplasmic dot-like inclusions as cytopathologically useful findings of ependymoma: Case report of adolescent supratentorial anaplastic ependymoma with clear cell morphology.
Clinical case reportsGrade III intradural extramedullary anaplastic ependymoma managed with near-complete resection and adjuvant radiotherapy: a case report.
Spinal cord series and cases[Visual fluorescence combined with laser spectroscopy in surgery for intramedullary spinal cord tumors].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoEpendymoma with C11orf95-MAML2 fusion: presenting with granular cell and ganglion cell features.
Brain tumor pathologyCervicodorsal extramedullary anaplastic ependymoma with intracranial metastasis.
Neuro-ChirurgieLong-term outcomes of spinal ependymomas: an institutional experience of more than 60 cases.
Journal of neuro-oncologyA phase II study of dose-dense temozolomide and lapatinib for recurrent low-grade and anaplastic supratentorial, infratentorial, and spinal cord ependymoma.
Neuro-oncologyEpendymoma, NOS and anaplastic ependymoma incidence and survival in the United States varies widely by patient and clinical characteristics, 2000-2016.
Neuro-oncology practiceThe potentially therapeutic targets of pediatric anaplastic ependymoma by transcriptome profiling.
NeoplasmaFahr's disease associated with anaplastic ependymoma: a case report and review of the literature.
British journal of neurosurgeryComparison of Conventional, Diffusion, and Perfusion MRI Between Low-Grade and Anaplastic Extraventricular Ependymoma.
AJR. American journal of roentgenologyRELA fusion-positive ependymoma accompanied by extensive desmoplasia: a case report.
Brain tumor pathologyRecurring pediatric anaplastic ependymoma with rare peritoneal carcinomatosis: a case report and hypothesis of mechanism.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryCorrigendum to 'Anaplastic ependymoma metastases through a ventriculoperitoneal shunt' [Radiology Case Reports 15 (2020) 650-654].
Radiology case reportsExtraneural metastatic anaplastic ependymoma: a systematic review and a report of metastases to bilateral parotid glands.
Neuro-oncology practiceMyalgia and Hematuria in Association with Clonidine and Arginine Administration for Growth Hormone Stimulation Tests.
Case reports in medicinecIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors.
Brain pathology (Zurich, Switzerland)Extensive craniospinal disseminated metastasis after the resection of intradural extramedullary ependymoma in the craniocervical junction: a case report and literature review.
The International journal of neuroscienceAnaplastic ependymoma metastases though a ventriculoperitoneal shunt.
Radiology case reportsTreatment outcome of anaplastic ependymoma under the age of 3 treated by intensity-modulated radiotherapy.
Radiation oncology journalCancer treatment in disabled children.
European journal of pediatricsContralateral Ventriculostomy for Intraoperative Brain Relaxation in Supratentorial Brain Tumors.
Neurology India[Turcot syndrome and Gardner's syndrome in a female patient with familial colon adenomatosis. A case report and literature review].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoTSC2 alterations in anaplastic ependymoma progression to ependymosarcoma.
Clinical neuropathologyCharcot-Marie-Tooth 1A concurrent with anaplastic ependymoma in a toddler: when an acute event unmasks a chronic condition.
The Turkish journal of pediatricsWorld Health Organization Grade III Supratentorial Extraventricular Ependymomas in Adults: Case Series and Review of Treatment Modalities.
Asian journal of neurosurgeryAcute and chronic hemorrhage from radiation-induced cavernous malformation associated with late-delayed radiation necrosis in long surviving glioma patients: A case report.
Oncology lettersUtility of copy number variants in the classification of intracranial ependymoma.
Cancer geneticsStroke-Like Migraine Attacks after Radiation Therapy Syndrome: Clinical and Imaging Characteristics.
Journal of clinical imaging scienceMYCN amplification drives an aggressive form of spinal ependymoma.
Acta neuropathologicaSpinal Cord Ependymomas With MYCN Amplification Show Aggressive Clinical Behavior.
Journal of neuropathology and experimental neurologyAnaplastic Ependymoma and Posterior Fossa Grouping in a Patient With H3K27ME3 Loss of Expression but Chromosomal Imbalance.
Advances in radiation oncologyNew therapeutic target for pediatric anaplastic ependymoma control: study of anti-tumor activity by a Kunitz-type molecule, Amblyomin-X.
Scientific reportsA Case of Recurrent Supratentorial Extraventricular Anaplastic Ependymoma in Adult.
Brain tumor research and treatmentAnaplastic ependymoma arising from the lower segment of the uterine corpus: Case report and literature review.
The journal of obstetrics and gynaecology researchMutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing.
F1000Research5-ALA fluorescence-guided surgery in pediatric brain tumors-a systematic review.
Acta neurochirurgicaSudden Unexpected Death in a Child From an Anaplastic Ependymoma.
The American journal of forensic medicine and pathologyDiagnostic errors during intramedullar processes.
Wiadomosci lekarskie (Warsaw, Poland : 1960)Freiburg Neuropathology Case Conference : Posterior Fossa Mass in an Infant.
Clinical neuroradiologyUnedited microneurosurgery of a pineal region ependymoma.
Surgical neurology internationalTelovelar Approach to Pediatric Fourth Ventricle Tumors: Feasibility and Outcome.
Turkish neurosurgeryIndividualized treatment for a case of recurrent ovarian ependymoma.
OncoTargets and therapyRadiosurgery or hypofractionated stereotactic radiotherapy after craniospinal irradiation in children and adults with medulloblastoma and ependymoma.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery[Radicalness and complications of repeated surgery for malignant neuroepithelial tumors of the posterior cranial fossa in children].
Zhurnal voprosy neirokhirurgii imeni N. N. BurdenkoMicrosurgical Resection of Anaplastic Ependymoma of the Cerebellopontine Angle in an Adult: 3-Dimensional Operative Video.
Operative neurosurgery (Hagerstown, Md.)Myxopapillary ependymoma with anaplastic features: A case report with review of the literature.
Surgical neurology internationalTreatment Outcomes in Children and Adolescents with Relapsed or Progressed Solid Tumors: a 20-year, Single-Center Study.
Journal of Korean medical scienceL1CAM Immunopositivity in Anaplastic Supratentorial Ependymomas: Correlation With Clinical and Histological Parameters.
International journal of surgical pathologyPediatric Case of Li-Fraumeni Syndrome Complicated with Supratentorial Anaplastic Ependymoma.
World neurosurgery[Implantation of VPS in the early postoperative period following removal of posterior cranial fossa tumors in children].
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko[A Surgical Case of Anaplastic Ependymoma Involving a Bridging Vein that Drained Directly into the Occipital Sinus].
No shinkei geka. Neurological surgeryPreoperative and intraoperative perfusion magnetic resonance imaging in a RELA fusion-positive anaplastic ependymoma: A case report.
Surgical neurology internationalPineal Anaplastic Ependymoma With Multifocal Intradural Extramedullary Metastases on MRI and 18FDG-PET.
Clinical nuclear medicineDNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment.
Neuro-oncologyGastroparesis Following Resection of a Fourth-Ventricle Ependymoma in a Child.
World neurosurgeryPrimary diffuse large B-cell lymphoma of the choroid plexus: A case report and review of the literature.
Surgical neurology internationalPoliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma.
Journal of neuropathology and experimental neurologyA Missed Differential in an Extra-Axial Lesion with Calvarial Involvement.
Annals of neurosciencesSimultaneous cerebrospinal fluid and hematologic metastases in a high-grade ependymoma.
Surgical neurology internationalSupratentorial Pure Cortical Ependymoma: An Unusual Lesion Causing Focal Motor Aware Seizure.
Journal of neurosciences in rural practicePrognostic Implications of Histological Clear Cells in High-Grade Intracranial Ependymal Tumors: A Retrospective Analysis from a Tertiary Care Hospital in Pakistan.
Asian journal of neurosurgeryRadiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma.
Pediatric blood & cancerIntracranial Neoplasms in the First Year of Life: Results of a Third Cohort of Patients From a Single Institution.
NeurosurgeryNeuroendoscopic Cylinder Surgery and 5-Aminolevulinic Acid Photodynamic Diagnosis of Deep-Seated Intracranial Lesions.
World neurosurgeryAdvantages of high b-value diffusion-weighted imaging for preoperative differential diagnosis between embryonal and ependymal tumors at 3 T MRI.
European journal of radiologyPediatric Isolated Cortical (Ectopic) Anaplastic Ependymoma.
Asian journal of neurosurgeryAdult Supratentorial Extraventricular Anaplastic Ependymoma: Therapeutic Approach and Clinical Review.
Asian journal of neurosurgeryMultimodal treatment including tandem high-dose chemotherapy and autologous stem cell transplantation in children with anaplastic ependymomas.
Pediatric transplantationSupratentorial Cortical Ependymomas: A Retrospective Series of 13 Cases at a Single Center.
World neurosurgeryMultifocal intradural extramedullary anaplastic ependymoma of the spine.
Journal of spine surgery (Hong Kong)Surgical Treatment of Spinal Ependymomas: Experience in 49 Patients.
World neurosurgerySupratentorial extraventricular ependymomas: A retrospective study focused on long-term outcomes and prognostic factors.
Clinical neurology and neurosurgeryEANO guidelines for the diagnosis and treatment of ependymal tumors.
Neuro-oncologyAggressive Supratentorial Ependymoma, RELA Fusion-Positive with Extracranial Metastasis: A Case Report.
Journal of pathology and translational medicineRELA fusion-positive anaplastic ependymoma: molecular characterization and advanced MR imaging.
Brain tumor pathologyEpendymomas arising outside of the central nervous system: A case series and literature review.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaRapid autopsy of a patient with recurrent anaplastic ependymoma.
Palliative & supportive careEpidemiology, molecular classification and WHO grading of ependymoma.
Journal of neurosurgical sciences[Radiation Necrosis in the Upper Cervical Spinal Cord in a Patient Treated with Proton Therapy after Radical Resection of the Fourth Ventricle Ependymoma].
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnostiEncouraging option of multi-staged gross total resection for a C11orf-RelA fusion-positive supratentorial anaplastic ependymoma.
Brain tumor pathologyClinical Features of a Family with Multiple Endocrine Neoplasia Type 2A Caused by the D631Y RET Mutation.
Thyroid : official journal of the American Thyroid AssociationSurgery for spinal intramedullary tumors: technique, outcome and factors affecting resectability.
Neurosurgical reviewSystemic metastases from central nervous system ependymoma: case report and review of the literature.
The neuroradiology journalSpinal cord anaplastic ependymoma induced by radiation treatment of breast cancer.
Journal of neurosurgical sciencesAnaplastic Ependymoma With Ganglionic Differentiation: Report of a Rare Case and Implications in Diagnosis.
International journal of surgical pathologyPediatric Basal Ganglia Region Tumors: Clinical and Radiologic Features Correlated with Histopathologic Findings.
World neurosurgeryHormonal based treatment of ovarian anaplastic ependymoma with anastrozole.
Gynecologic oncology reportsMultiple intradural-extramedullary spinal ependymomas including tumors with different histological features.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research SocietyLipomatous/Extensively Vacuolated Ependymoma with Signet-Ring Cell-Like Appearance: Analysis of a Case with Extensive Literature Review.
Case reports in pathology"Drop" Metastases from an Operated Case of Intracranial Anaplastic Ependymoma Identified on Fluoro-2-deoxyglucose Positron Emission Tomography/Computed Tomography.
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaExtra-axial giant falcine ependymoma with ultra-rapid growth in child: Uncommon entity with literature review.
Journal of pediatric neurosciencesFeline glioma: a retrospective study and review of the literature.
Journal of feline medicine and surgeryUpdate on malignancies in children with juvenile idiopathic arthritis in the German BIKER Registry.
Clinical and experimental rheumatologyAngiocentric glioma transformed into anaplastic ependymoma: Review of the evidence for malignant potential.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaMagnetic resonance imaging findings of extraventricular anaplastic ependymoma: A report of 11 cases.
Oncology lettersNovel fusion genes and chimeric transcripts in ependymal tumors.
Genes, chromosomes & cancerAltered MicroRNA Expression Is Associated with Tumor Grade, Molecular Background and Outcome in Childhood Infratentorial Ependymoma.
PloS oneBrain Tumor in an In Vitro Fertilization-Facilitated Pregnancy: Fourth Ventricle Anaplastic Ependymoma in the Second Trimester.
Journal of neurological surgery reportsSupratentorial extraventricular WHO grade III (anaplastic) ependymoma 17 years after total removal of WHO grade II ependymoma of the fourth ventricle.
British journal of neurosurgeryPure extra-axial supratentorial anaplastic ependymoma with no cortical attachment: A rare case.
Neurology IndiaPrimary Intracranial Extra-Axial Anaplastic Ependymomas.
World neurosurgeryRadiation-induced anaplastic ependymoma mimicking a skull base meningioma: A case report.
Experimental and therapeutic medicineRe-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy.
Japanese journal of radiologyAutonomic dysfunction elicited by a medulla oblongata injury after fourth ventricle tumor surgery in a pediatric patient.
Autonomic neuroscience : basic & clinicalAnaplastic extramedullary cervical ependymoma with leptomeningeal metastasis.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaAn extraneural primary anaplastic ependymoma at the subcutaneous inguinal region: Report of a rare case.
Indian journal of pathology & microbiologyAnaplastic Ependymoma in a Child With Sickle Cell Anemia: A Case Report Highlighting Treatment Challenges for Young Children With Central Nervous System Tumors and Underlying Vasculopathy.
Pediatric blood & cancerMultiomics approach showing genome-wide copy number alterations and differential gene expression in different types of North-Indian pediatric brain tumors.
GeneA rare case of malignant pediatric ectomesenchymoma arising from the cerebrum.
International journal of clinical and experimental pathologyTemozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression.
Pediatric blood & cancerRole of Evaluating MGMT Status and 1p36 Deletion in Radiosurgery-Induced Anaplastic Ependymoma That Rapidly and Completely Resolved by Temozolomide Alone: Case Report and Review of the Literature.
Journal of neurological surgery reportsMalignant Transformation of Grade II Ependymoma in a 2-Year-Old Child: Case Report.
Journal of neurological surgery reportsQualitative analysis of spinal intramedullary lesions using PET/CT.
Journal of neurosurgery. SpineAn 11 Year Old Child with a Right Parieto-Occipital Lesion. Anaplastic Ependymoma (WHO Grade III) with Granular Cell Features.
Brain pathology (Zurich, Switzerland)Predictors of survival in patients with spinal ependymoma.
Neurological researchPaediatric intracranial anaplastic ependymoma: the role of multiple surgical resections for disease relapse in maintaining quality of life and prolonged survival.
Pediatric neurosurgeryAn open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).
Journal of neuro-oncologyAnaplastic ependymoma of spinal cord presented with low back pain.
The spine journal : official journal of the North American Spine SocietyInfratentorial ependymomas--a study of the centre in Katowice.
Child's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryAn integrative analysis of treatment, outcomes and prognostic factors for primary spinal anaplastic ependymomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of AustralasiaNeoadjuvant chemotherapy for brain tumors in infants and young children.
Journal of neurosurgery. PediatricsEvaluating the apparent diffusion coefficient in MRI studies as a means of determining paediatric brain tumour stages.
Neurologia (Barcelona, Spain)Associações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Thoracic tanycytic ependymoma with anaplastic progression after subtotal resection and repeated radiotherapy: A 17-year follow-up case report.
- Nivolumab-Associated Autoimmune Encephalopathy in a Child With Multiply Relapsed Anaplastic Ependymoma.
- Recurrent pediatric posterior fossa anaplastic ependymoma managed with multiple resections: illustrative case.
- Clinical Features and Prognostic Indicators for Brainstem Ependymomas : A Population-Based Retrospective Surveillance, Epidemiology, and End Results Database Analysis.
- Characteristics and therapeutic profile of the patients with upper cervical spinal cord ependymoma from the medulla oblongata to C4: A cohort of 108 cases.
- Extraspinal sacrococcygeal anaplastic ependymoma: A case report.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:251646(Orphanet)
- MONDO:0016700(MONDO)
- GARD:10634(GARD (NIH))
- Busca completa no PubMed(PubMed)
- Q19000645(Wikidata)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
