Raras
Buscar doenças, sintomas, genes...
Schwannoma benigno
ORPHA:252164CID-10 · D36.1CID-11 · 2F3YDOENÇA RARA

Tumor benigno, geralmente encapsulado, de crescimento lento, composto por células de Schwann. Afeta nervos periféricos e cranianos. Recorre com pouca frequência e apenas casos raros associados a transformação maligna foram relatados.

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

Tumor benigno, geralmente encapsulado, de crescimento lento, composto por células de Schwann. Afeta nervos periféricos e cranianos. Recorre com pouca frequência e apenas casos raros associados a transformação maligna foram relatados.

Pesquisas ativas
4 ensaios
146 total registrados no ClinicalTrials.gov
Publicações científicas
531 artigos
Último publicado: 2026

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-9 / 100 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
6.0
Europe
Início
Adult
+ elderly
🏥
SUS: Sem cobertura SUSScore: 0%
CID-10: D36.1
Você se identifica com essa condição?
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

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Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

👂
Ouvidos
5 sintomas
🧠
Neurológico
5 sintomas
🦴
Ossos e articulações
4 sintomas
🫃
Digestivo
2 sintomas
😀
Face
2 sintomas
🫘
Rins
1 sintomas

+ 25 sintomas em outras categorias

Características mais comuns

90%prev.
Morfologia anormal do nervo craniano
Muito frequente (99-80%)
90%prev.
Schwannoma vestibular
Muito frequente (99-80%)
90%prev.
Schwannoma
Muito frequente (99-80%)
90%prev.
Anormalidade da eletrofisiologia do sistema nervoso periférico
Muito frequente (99-80%)
90%prev.
Schwannoma escleral
Muito frequente (99-80%)
90%prev.
Morfologia anormal do osso temporal
Muito frequente (99-80%)
47sintomas
Muito frequente (7)
Frequente (4)
Ocasional (13)
Muito raro (1)
Sem dados (22)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 47 características clínicas mais associadas, ordenadas por frequência.

Morfologia anormal do nervo cranianoAbnormal cranial nerve morphology
Muito frequente (99-80%)90%
Schwannoma vestibularVestibular schwannoma
Muito frequente (99-80%)90%
Schwannoma
Muito frequente (99-80%)90%
Anormalidade da eletrofisiologia do sistema nervoso periféricoAbnormality of peripheral nervous system electrophysiology
Muito frequente (99-80%)90%
Schwannoma escleralScleral schwannoma
Muito frequente (99-80%)90%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico531PubMed
Últimos 10 anos179publicações
Pico202221 papers
Linha do tempo
2026Hoje · 2026🧪 1996Primeiro ensaio clínico📈 2022Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

Genes associados

4 genes identificados com associação a esta condição. Padrão de herança: Not applicable.

NF2MerlinCandidate gene tested inAltamente restrito
FUNÇÃO

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppress

LOCALIZAÇÃO

Cell projection, filopodium membraneCell projection, ruffle membraneNucleusCytoplasm, perinuclear regionCytoplasmic granuleCytoplasm, cytoskeleton

VIAS BIOLÓGICAS (2)
Regulation of actin dynamics for phagocytic cup formationRHO GTPases activate PAKs
MECANISMO DE DOENÇA

Schwannomatosis, vestibular

An autosomal dominant neoplasia syndrome characterized by the development of multiple benign nerve sheath tumors called schwannomas, particularly affecting the vestibular nerve. Affected individuals usually present with bilateral vestibular schwannomas but can have schwannomas on other cranial, spinal, and peripheral/cutaneous nerves. Meningiomas are common, whereas 20 to 35% of affected individuals develop intramedullary spinal cord tumors called ependymomas. The condition is also characterized by several ophthalmic features such as lenticular opacities, retinal hamartoma, epiretinal membranes.

EXPRESSÃO TECIDUAL(Ubíquo)
Cerebelo
30.4 TPM
Cérebro - Hemisfério cerebelar
27.6 TPM
Córtex cerebral
25.9 TPM
Fibroblastos
25.9 TPM
Brain Frontal Cortex BA9
24.3 TPM
OUTRAS DOENÇAS (5)
NF2-related schwannomatosisfamilial meningiomamosaic NF2-related schwannomatosismeningioma
HGNC:7773UniProt:P35240
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrialCandidate gene tested inTolerante
FUNÇÃO

FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis (PubMed:26260787, PubMed:38425362). Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid (PubMed:26260787, PubMed:38425362). Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-m

LOCALIZAÇÃO

Mitochondrion inner membraneGolgi apparatusCell projection

VIAS BIOLÓGICAS (1)
Ubiquinol biosynthesis
MECANISMO DE DOENÇA

Coenzyme Q10 deficiency, primary, 6

An autosomal recessive disorder characterized by onset in infancy of severe progressive nephrotic syndrome resulting in end-stage renal failure and sensorineural deafness. Renal biopsy usually shows focal segmental glomerulosclerosis.

VIAS REACTOME (1)
OUTRAS DOENÇAS (2)
familial steroid-resistant nephrotic syndrome with sensorineural deafnessschwannomatosis
HGNC:20233UniProt:Q9Y2Z9
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1Candidate gene tested inAltamente restrito
FUNÇÃO

Core component of the BAF (hSWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures

LOCALIZAÇÃO

Nucleus

VIAS BIOLÓGICAS (8)
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not knownRMTs methylate histone argininesFormation of neuronal progenitor and neuronal BAF (npBAF and nBAF)Formation of the embryonic stem cell BAF (esBAF) complexFormation of the polybromo-BAF (pBAF) complex
MECANISMO DE DOENÇA

Rhabdoid tumor predisposition syndrome 1

A familial cancer syndrome predisposing to renal or extrarenal malignant rhabdoid tumors and to a variety of tumors of the central nervous system, including choroid plexus carcinoma, medulloblastoma, and central primitive neuroectodermal tumors. Rhabdoid tumors are the most aggressive and lethal malignancies occurring in early childhood.

EXPRESSÃO TECIDUAL(Ubíquo)
Linfócitos
136.4 TPM
Testículo
110.5 TPM
Cérebro - Hemisfério cerebelar
98.7 TPM
Cerebelo
93.5 TPM
Ovário
93.2 TPM
OUTRAS DOENÇAS (9)
rhabdoid tumor predisposition syndrome 1intellectual disability, autosomal dominant 15familial multiple meningiomaschwannomatosis
HGNC:11103UniProt:Q12824
LZTR1Leucine-zipper-like transcriptional regulator 1Candidate gene tested inTolerante
FUNÇÃO

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras (K-Ras/KRAS, N-Ras/NRAS and H-Ras/HRAS) (PubMed:30442762, PubMed:30442766, PubMed:30481304). Is a negative regulator of RAS-MAPK signaling that acts by controlling Ras levels and decreasing Ras association with membranes (PubMed:30442762, PubMed:30442766, PubMed:30481304)

LOCALIZAÇÃO

Endomembrane systemRecycling endosomeGolgi apparatus

MECANISMO DE DOENÇA

Glioma

Gliomas are benign or malignant central nervous system neoplasms derived from glial cells. They comprise astrocytomas and glioblastoma multiforme that are derived from astrocytes, oligodendrogliomas derived from oligodendrocytes and ependymomas derived from ependymocytes.

EXPRESSÃO TECIDUAL(Ubíquo)
Pituitária
76.5 TPM
Nervo tibial
68.8 TPM
Útero
67.8 TPM
Cervix Ectocervix
65.1 TPM
Cervix Endocervix
61.7 TPM
OUTRAS DOENÇAS (9)
Noonan syndrome 10RASopathyNoonan syndrome 2cafe au lait spots, multiple
HGNC:6742UniProt:Q8N653

Variantes genéticas (ClinVar)

854 variantes patogênicas registradas no ClinVar.

🧬 NF2: NM_000268.4(NF2):c.1333G>T (p.Glu445Ter) ()
🧬 NF2: NM_000268.4(NF2):c.294del (p.Lys99fs) ()
🧬 NF2: NM_000268.4(NF2):c.271C>T (p.Pro91Ser) ()
🧬 NF2: NM_000268.4(NF2):c.183del (p.Phe62fs) ()
🧬 NF2: NM_000268.4(NF2):c.44del (p.Lys15fs) ()
Ver todas no ClinVar

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

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Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
·Pré-clínico4
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 4 ensaios
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Schwannoma benigno

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Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

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Publicações mais relevantes

Timeline de publicações
180 papers (10 anos)
#1

Successful Sphincter-Preserving Resection of a Giant Rectal Schwannoma Using Transanal Total Mesorectal Excision: A Case Report.

Surgical case reports2026

Rectal schwannomas are rare, accounting for less than 10% of all gastrointestinal schwannomas. When they are large and located in the lower rectum, achieving complete resection while preserving sphincter function can be technically challenging. Transanal total mesorectal excision (TaTME) provides an enhanced view of the deep pelvis and facilitates precise dissection around the anorectal junction. We report a case of a giant rectal schwannoma that was successfully resected with anal preservation using TaTME. A 30-year-old woman was referred with an 11-cm rectal tumor in the pelvis identified during pregnancy. MRI revealed a well-circumscribed mass surrounding the lower rectum, in broad contact with the uterus, vagina, and anal sphincter. Endoscopic ultrasound-guided fine-needle aspiration demonstrated a benign schwannoma. Considering the patient's strong desire for sphincter preservation, laparoscopic intersphincteric resection assisted by TaTME was performed. The operative time was 317 minutes with minimal blood loss (35 mL). The tumor was completely resected with negative margins, and no diverting stoma was required. Pathology confirmed a plexiform schwannoma without malignancy. The postoperative course was uneventful, and the patient was discharged on POD 12. At 3 months postoperatively, anal function was satisfactory, with a Low Anterior Resection Syndrome score of 14 indicating only minor symptoms. TaTME is a useful surgical strategy for large rectal tumors in which conventional laparoscopic approaches provide limited visualization. This approach enabled complete resection with preservation of anal sphincter function in a patient with a giant rectal schwannoma.

#2

A schwannoma of the olfactory nerve: a case report of a diagnostic challenge and review of the literature.

Journal of surgical case reports2026 Feb

Olfactory groove schwannomas are exceptionally rare intracranial tumors that present a significant diagnostic challenge, as they are frequently misidentified as meningiomas on preoperative imaging. We report the case of a 44-year-old woman who presented with a two-month history of headache and blurred vision. Neuroimaging revealed a large, dural-based, homogeneously enhancing extra-axial mass in the left frontal region, strongly suggestive of a meningioma. The patient underwent surgical excision of the lesion. Histopathological examination, however, revealed the classic features of a benign schwannoma, including Antoni A and B areas, nuclear palisading, and Verocay bodies. This diagnosis was confirmed by an immunohistochemical profile that was positive for S100 and negative for Epithelial Membrane Antigen. This case underscores the limitations of radiological diagnosis for skull base lesions and highlights the critical role of histopathological and immunohistochemical analysis in achieving a definitive diagnosis, which is paramount for guiding appropriate management.

#3

Incidental obturator nerve schwannoma mimicking nodal disease during radical prostatectomy: Resolution of chronic neuropathic pain after intracapsular nerve-sparing excision.

Urology case reports2026 Jan

We report a rare case of obturator nerve schwannoma incidentally found during laparoscopic radical prostatectomy in a 68-year-old man with a 20-year history of chronic thigh pain. Initially interpreted as lymphadenopathy on MRI, the lesion was excised via intracapsular, nerve-sparing resection. Histopathology confirmed a benign schwannoma. The patient experienced >90 % pain relief, regained urinary continence by day 30, and is recovering erectile function. At six months, he remains symptom-free. Obturator schwannomas are extremely rare and can mimic nodal disease. Minimally invasive, nerve-sparing excision during pelvic oncologic surgery is safe and effective when performed by experienced surgeons.

#4

Scalp schwannomas as a rare entity with common misdiagnoses: A case report and systematic literature review.

Surgical neurology international2025

Scalp schwannomas are rare, benign peripheral nerve sheath tumors often misdiagnosed due to their nonspecific presentation. They typically present as slow-growing, painless subcutaneous nodules, most commonly in the occipital region. We report a 29-year-old female with a gradually enlarging, painless occipital scalp nodule for 7 months. Clinically, it was suspected to be a lipoma or pilar cyst. Excision under local anesthesia revealed a well-encapsulated, yellowish mass. Histopathology confirmed a benign schwannoma. The patient had an uneventful recovery with no recurrence at 6-month follow-up. Scalp schwannomas, though rare, exhibit characteristic clinical and histopathological features. They are frequently misdiagnosed due to their rare occurrence as well as their clinical and radiological resemblance to other benign lesions. Complete surgical excision is the preferred treatment, offering an excellent prognosis with minimal risk of recurrence. Extended follow-up is recommended to monitor potential late recurrences.

#5

Transcriptomic analysis reveals novel targets in benign schwannoma using machine learning.

Neuroscience2025 Aug 16

This study aimed to identify key immune-related biomarkers of benign schwannoma through machine learning-assisted transcriptomic and single-cell analyses, and to construct a predictive model for disease evaluation. Transcriptomic data from the GSE108524 dataset were utilized for immune subtyping and immune cell infiltration analysis. Key biomarkers were screened using the Least Absolute Shrinkage and Selection Operator (LASSO), Support Vector Machine (SVM), and Random Forest algorithms. A nomogram-based predictive model was developed (area under the curve [AUC] = 0.67) and evaluated using accuracy, sensitivity, specificity, and F1-score metrics. The distribution of identified biomarkers across immune cell subsets was validated using scRNA-seq, with a particular focus on T cells and macrophages. Functional roles of ANGPTL1, IL17RC, LTBR, OLR1, and TGFBR1 were further verified through in vitro assays and in vivo using an NF2-knockout mouse model. Five immune-related biomarkers were identified. Among them, ANGPTL1 and IL17RC inhibited tumor cell proliferation and migration, whereas LTBR, OLR1, and TGFBR1 promoted these processes. These genes exhibited differential expression across immune subtypes and were enriched in tumor-associated immune cells. Both in vitro and in vivo experiments substantiated their biological significance in schwannoma progression. This study identifies five novel immune-related biomarkers with functional relevance in benign schwannoma, providing new insights into its immune microenvironment and tumor biology. The predictive model offers a foundation for risk stratification and personalized therapeutic strategies. These findings complement known markers such as NF2, SOX10, and S100B, highlighting their potential translational value as diagnostic and therapeutic targets.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC145 artigos no totalmostrando 178

2026

Successful Sphincter-Preserving Resection of a Giant Rectal Schwannoma Using Transanal Total Mesorectal Excision: A Case Report.

Surgical case reports
2026

A schwannoma of the olfactory nerve: a case report of a diagnostic challenge and review of the literature.

Journal of surgical case reports
2025

A Rare Case of Benign Esophageal Schwannoma.

Cureus
2026

Incidental obturator nerve schwannoma mimicking nodal disease during radical prostatectomy: Resolution of chronic neuropathic pain after intracapsular nerve-sparing excision.

Urology case reports
2025

Retroperitoneal Schwannoma: A Case Report and Diagnostic Approach to Retroperitoneal Masses.

Cureus
2025

Oral Lesions With Identical Clinical Presentation and Different Histopathological Diagnoses: A Case Series of Mucocele, Schwannoma, and Hamartoma.

Cureus
2025

Scalp schwannomas as a rare entity with common misdiagnoses: A case report and systematic literature review.

Surgical neurology international
2025

Laparoscopic Sleeve Gastrectomy for an Obese Patient with Retroperitoneal Schwannoma: A Case Report.

Surgical case reports
2025

Soft tissue myxofibrosarcoma in the right lower limb: a case report.

Journal of medical case reports
2025

Cardiac Schwannoma: A Clinical Case Report and Diagnostic Perspectives.

Surgical case reports
2025

An Intraperitoneal Schwannoma Diagnosed Using EUS-guided Tissue Acquisition: A Marking Clip and Fluoroscopy Technique Ensuring Safety and Preventing Accidental Esophageal Puncture.

Internal medicine (Tokyo, Japan)
2025

Intramedullary Schwannoma of the Conus Medullaris Presenting With Progressive Paraparesis: A Rare Case From a Resource-Limited Setting.

Clinical case reports
2025

Surgical Management of a Giant Mediastinal Schwannoma Associated with Neurofibromatosis Type 1: A Case Report.

Surgical case reports
2025

Cervical Sympathetic Chain Schwannoma in the Parapharyngeal Space: A Rare Case and Literature Review.

Ear, nose, &amp; throat journal
2025

Thoracoscopic Resection of an Esophageal Schwannoma Demonstrating a Malignant Pattern on Dual-Time-Point FDG-PET: A Case Report.

Surgical case reports
2025

Transcriptomic analysis reveals novel targets in benign schwannoma using machine learning.

Neuroscience
2025

Perirenal schwannoma mimicking a renal mass: A diagnostic pitfall - Case report.

Urology case reports
2025

Sacral intraosseous schwannoma in an adolescent patient: A case report.

Radiology case reports
2025

Asymptomatic ileal schwannoma with serial CT imaging.

BMJ case reports
2025

Simultaneous Bilateral Video-Assisted Thoracoscopic Surgery in the Prone Position for Resection of a Large Middle Mediastinal Tumor: A Case Report.

Cureus
2025

A Case of Pediatric Retroperitoneal Schwannoma Presenting with Myoclonus of the Lower Limb: A Case Report and Review.

Surgical case reports
2025

Endoscopic full-thickness resection of rectal schwannoma: A case report.

World journal of gastrointestinal endoscopy
2025

Uncommon retroperitoneal mass in a young adult: A rare case report of retroperitoneal schwannoma and review of diagnostic challenges.

International journal of surgery case reports
2024

Axillary Peripheral Nerve Schwannoma: A Rare Occurrence in the Torso.

Cureus
2024

Recurrent Ulnar Nerve Schwannoma in the Cubital Tunnel Elbow: A Rare Presentation and Surgical Management.

Cureus
2024

Obturator nerve schwannoma: a case report and review of the robotic literature.

Journal of surgical case reports
2024

A giant pelvic infiltrating schwannoma misdiagnosed as an ovarian neoplasm that was resected using a laparoscopic approach: A case report.

International journal of surgery case reports
2024

Image features and clinical analysis of retroperitoneal pelvic schwannoma: a case report.

BMC neurology
2024

Gross total resection of benign retroperitonealy/intra/paraspinal giant schwannoma.

Surgical neurology international
2024

Benign hepatic schwannoma in a patient with chronic hepatitis B infection: A case report.

Radiology case reports
2024

Retroperitoneal pelvic schwannoma: A rare case report and review of the literature.

Radiology case reports
2024

Gastric schwannoma: a case report.

Journal of surgical case reports
2024

Robotic-Assisted Resection of a Benign Schwannoma of the Obturator Nerve: A Rare Case.

The American journal of case reports
2024

Long-term postoperative outcomes of spinal cellular schwannoma: study of 93 consecutive cases.

The spine journal : official journal of the North American Spine Society
2024

Unilateral orbital schwannoma arising from the supraorbital nerve: Report of a rare case.

Clinical case reports
2023

Complete clinical remission of malignant peritoneal mesothelioma with systemic pemetrexed and bevacizumab in a patient with a BAP1 mutation.

BMJ case reports
2023

An Unusual Finding of a Neurogenic Tumor of the Trachea: A Tracheal Schwannoma.

Cureus
2023

Giant benign intrathoracic schwannoma: a decade-long progression towards fatality.

Journal of cardiothoracic surgery
2023

A Rare Case of Pediatric Oropharyngeal Schwannoma.

Cureus
2023

PET Scanning May Not Distinguish Benign Schwannoma from Metastasis in a Patient with Lung Adenocarcinoma.

European journal of case reports in internal medicine
2023

Diagnosing Schwannoma in the Wrist: a Challenging Case of Intraneural Ganglion Cyst Mimicry and a Review of Literature.

Case reports in plastic surgery &amp; hand surgery
2023

A rare histopathological variant of Schwannoma with rosette-like arrangements and epithelioid cells: a case report from a histopathologist's perspective.

Journal of the Korean Association of Oral and Maxillofacial Surgeons
2023

Spontaneous malignant transformation of trigeminal schwannoma: consideration of responsible gene alterations for tumorigenesis-a case report.

Brain tumor pathology
2023

Schwannoma: A Rare Case of Submucosal Gastric Tumor.

Diagnostics (Basel, Switzerland)
2022

Rare Schwannomas of Head and Neck and Review of Literature.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
2023

A rare case of left parapharyngeal space large schwannoma of unknown origin.

Journal of surgical case reports
2023

A Rare Sigmoid-Colon Schwannoma in a Premenopausal Woman: A Case Report.

Acta medica Lituanica
2022

Schwannoma of the Ascending Colon in a 22-Year-Old Male: A Case Report.

Cureus
2022

A Rare Case of Malignant Peripheral Nerve Sheath Tumor of Larynx.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
2022

Plexiform Melanocytic Schwannoma: Report of a Second Case and Overview of a Rare Entity.

The American Journal of dermatopathology
2022

Robot-assisted thoracoscopic surgery for large apical schwannoma in an obese patient.

General thoracic and cardiovascular surgery cases
2022

Paraglottic space schwannoma: a case report and literature review.

The Journal of international medical research
2023

Differentiation of benign and malignant spinal schwannoma using guided attention inference networks on multi-source MRI: comparison with radiomics method and radiologist-based clinical assessment.

Acta radiologica (Stockholm, Sweden : 1987)
2022

A 68-Year-Old Woman Presenting with Recurrent Abdominal Pain and a Diagnosis of a Presacral Retroperitoneal Benign Schwannoma that Mimicked an Ovarian Tumor on Pelvic Magnetic Resonance Imagining.

The American journal of case reports
2022

Case Report: Neuroblastoma-Like Schwannoma in a Domestic Short-Haired Cat.

Frontiers in veterinary science
2022

A case of a giant thoracic schwannoma.

Surgical neurology international
2022

Understanding the Molecular Mechanism of Vestibular Schwannoma for Hearing Preservation Surgery: Otologists' Perspective from Bedside to Bench.

Diagnostics (Basel, Switzerland)
2022

[Child with a vascularized throat mass].

HNO
2022

Video-assisted thoracoscopic resection of a thoracic inlet schwannoma with neuroforaminal involvement: a case report.

AME case reports
2022

A rare case of penile schwannomatosis presenting with painful nocturnal penile tumescence.

Basic and clinical andrology
2022

Successful treatment of pancreatic schwannoma by enucleation: A case report.

Medicine
2022

Curious Case of Acoustic Schwannoma of Middle Cranial Fossa: A Case Report.

Brain tumor research and treatment
2021

Giant schwannoma of thoracic vertebra: A case report.

World journal of clinical cases
2022

Laparoscopic excision of a schwannoma arising in the psoas muscle.

Journal of minimal access surgery
2022

Benign Schwannoma of the Thumb; a diagnostic challenge.

Radiology case reports
2021

Schwannoma of the Appendix Orifice.

Case reports in pathology
2021

Clinical outcome after surgery on schwannomas in the extremities.

World journal of orthopedics
2022

Presacral Benign Schwannoma Mimics Malignancy on 18F-FDG and 68Ga-FAPI PET/CT.

Clinical nuclear medicine
2021

Surgical Excision of a Giant Schwannoma of the Hand: A Case Report.

JBJS case connector
2021

Multiple schwannomas of the facial nerve mimicking cervical lymphoma: a case report.

Journal of medical case reports
2021

A Solitary Benign Schwannoma of the Medial Dorsal Cutaneous Nerve of the Foot Masquerading as a Ganglion Cyst.

Cureus
2021

Varied foci of primary benign schwannoma of the thorax: a case series.

Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
2021

Schwannoma originating in the soft palate: A case report.

International journal of surgery case reports
2021

Schwannoma mimicking pancreatic carcinoma: A case report.

World journal of clinical cases
2021

PET/CT and contrast-enhanced CT imaging findings in benign solitary schwannomas.

European journal of radiology
2021

[Vagal Schwannoma in the Middle Mediastinum Found by Atelectasis on Chest X-ray:Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery
2022

Diagnostic Dilemma of Retroperitoneal Schwannomas Encountered in a Specialized Gynecology Hospital.

Journal of investigative surgery : the official journal of the Academy of Surgical Research
2021

Large benign schwannoma of the greater omentum with synchronous cervical cancer: A case report.

International journal of surgery case reports
2021

Multimodal ultrasound imaging of primary thyroid schwannoma: A case report.

Medicine
2021

Left atrial schwannoma in schwannomatosis: a case report.

Surgical case reports
2021

Symptomatic Abdominal Wall Schwannoma Mimicking Infected Subcutanous Soft Tissue Lesion. A Case report.

International journal of surgery case reports
2021

[Primary benign schwannoma of the pleura: Report of 2 cases].

Revue des maladies respiratoires
2020

Robot-Assisted Nerve-Sparing Excision of a Symptomatic Obturator Nerve Schwannoma: A Case Report.

Cureus
2020

Benign Schwannoma of the Lateral Plantar Nerve: A Case Report.

Journal of the American Podiatric Medical Association
2020

Ascending Colon Schwannoma Surgically Treated after Accurate Preoperative Diagnosis.

Case reports in gastroenterology
2020

Laparoscopic resection of a primary diaphragmatic schwannoma: a case report and literature review.

BMC surgery
2020

Giant Intrathoracic Schwannoma: A Case Report.

In vivo (Athens, Greece)
2020

Retroperitoneal robot-assisted resection of a lower posterior mediastinal benign schwannoma using a transdiaphragmatic approach: A case report.

Medicine
2022

Abducens Nerve Schwannoma: First Case to Be Treated With an Expanded Endonasal Approach.

Ear, nose, &amp; throat journal
2020

Deceptive Features on Surveillance Imaging of Intraneural Metastatic Deposits in Metastatic Renal Cell Cancer.

World neurosurgery
2020

Schwannoma in the hepatoduodenal ligament with portal vein invasion: A case report.

Medicine
2021

Giant extradural spinal schwannoma in a non-neurofibromatosis child-case report and review of literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
2020

Isolated schwannoma of the urinary bladder: a case report and review of the literature.

The Pan African medical journal
2021

Intraocular schwannoma with extrascleral extension.

European journal of ophthalmology
2020

Abdominal wall schwannoma: a case report.

Gastroenterology and hepatology from bed to bench
2019

An interdisciplinary approach for laparoscopic removal of a large retroperitoneal pelvic schwannoma attached to vital vessels: A case report.

Medicine
2020

Robotic-assisted surgical removal of retroperitoneal schwannoma by transmesocolic access.

International braz j urol : official journal of the Brazilian Society of Urology
2019

Benign schwannoma of posterior mediastinum accompanied by bloody pleural effusion misdiagnosed as solitary fibrous tumor: A case report.

Caspian journal of internal medicine
2020

Schwannoma of the long thoracic nerve in the left axilla: a case report.

The Journal of international medical research
2019

A laparoscopic treatment of a suspicious adrenal mass revealing an unsual cause of adrenal incidentaloma.

The Pan African medical journal
2020

Pseudoglandular schwannoma mimicking alveolar rhabdomyosarcoma: A diagnostic challenge on fine-needle cytology.

Diagnostic cytopathology
2020

Atypical Schwannoma: A 10-year experience.

American journal of otolaryngology
2019

Giant paravertebral schwannoma near the lumbar nerve roots with bone destruction: A case report.

Medicine
2019

External Oblique Muscle Schwannoma: A Rare Anatomical Presentation.

Case reports in surgery
2022

Mediastinal Ancient Schwannoma Causing Intrathoracic Bleeding.

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
2019

Rare case of double migration of thoracic intradural schwannoma.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2019

Synchronous Presentation of a Cervical Spinal Schwannoma and Primary Progressive Multiple Sclerosis in a 65-year-old Man.

Cureus
2019

Intestinal Schwannoma: A Clinicopathological, Immunohistochemical, and Prognostic Study of 9 Cases.

Gastroenterology research and practice
2019

Schwannoma of the uterine cervix: a rare case report.

Obstetrics &amp; gynecology science
2019

Left lower lobe sleeve resection for endobronchial schwannoma.

Annals of translational medicine
2019

Multiple schwannomas of the digital nerves and common palmar digital nerves: An unusual case report of multiple schwannomas in one hand.

Medicine
2018

Benign Schwannoma of the Rectus Sheath: A Rare Abdominal Mass Treated in a Multidisciplinary Fashion.

The American surgeon
2018

Angiographic embolization followed by piecemeal resection of giant posterior mediastinal schwannoma: Case report and concise review.

International journal of surgery case reports
2018

A rare case of isolated schwannoma in infraorbital nerve.

Archives of craniofacial surgery
2018

[Primary Hepatic Schwannoma].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
2018

Intraosseous schwannoma of the mobile spine: a report of twenty cases.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
2018

Prognostic Analysis of Clinical and Immunohistochemical Factors for Patients with Spinal Schwannoma.

World neurosurgery
2018

Solitary Benign Schwannoma Mimics Residual Malignancy on FDG PET/CT.

Clinical nuclear medicine
2018

Giant posterior pararenal schwannoma: A case report and review of literature.

Molecular and clinical oncology
2018

Imaging-Ambiguous Lesions of Meckel's Cave-Utility of Endoscopic Endonasal Transpterygoid Biopsy.

World neurosurgery
2018

Lower posterior mediastinal benign schwannoma successfully resected with retroperitoneoscopy using a transdiaphragmatic approach: A case report.

Thoracic cancer
2018

Toe walking after three: how serious could it be?

BMJ case reports
2019

Laparoscopic excision of a retroperitoneal schwannoma: A case report.

Asian journal of endoscopic surgery
2018

A Rare Duodenal Subepithelial Tumor: Duodenal Schwannoma.

Clinical endoscopy
2018

Mediastinal epithelioid angiosarcoma arising in schwannoma: The first case in the literature.

Turk gogus kalp damar cerrahisi dergisi
2017

[An unusual cause of high dysphagia: schwannoma of the preepiglottic space].

The Pan African medical journal
2018

Advantage of laparoscopic resection for pelvic Schwannoma: Case report and review of the literature.

International journal of surgery case reports
2017

[Entrapment neuropathy in the foot revealing schwannoma of the superficial peroneal nerve: outcome of conservative surgical treatment].

The Pan African medical journal
2018

Middle mediastinal schwannoma concealed by asthma and GORD.

BMJ case reports
2018

Successful treatment of a giant ossified benign mesenteric schwannoma.

World journal of gastroenterology
2017

Combined thoracoscopic and endoscopic surgery for a large esophageal schwannoma.

World journal of gastroenterology
2017

Case report: schwannoma arising from the unilateral adrenal area with bilateral hyperaldosteronism.

BMC endocrine disorders
2017

Schwannoma of the vagina - a common tumor but a rare location: A case report.

Molecular and clinical oncology
2017

Endocardial Peripheral Nerve Sheath Tumour with Features of a Benign Schwannoma in a Donkey.

Journal of comparative pathology
2017

Clinical Features and Surgical Treatment of Schwannoma Affecting the Base of the Tongue: A Systematic Review.

International archives of otorhinolaryngology
2017

[Resection of a Posterior Mediastinal Tumor Using Intraoperative Motor Evoked Potential Monitoring;Report of a Case].

Kyobu geka. The Japanese journal of thoracic surgery
2017

Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case.

Molecular and clinical oncology
2018

Solitary Benign Schwannoma of the Foot Presenting Clinically as a Ganglion Cyst A Case Study.

Journal of the American Podiatric Medical Association
2017

A case of pancreatic schwannoma showing increased FDG uptake on PET/CT.

International journal of surgery case reports
2017

Schwannoma of the femur: A rare case report.

Journal of bone oncology
2017

Spindle cell type malignant peripheral nerve sheath tumor arising in benign schwannoma with multiple intraosseous spinal metastasis: A case report.

Journal of back and musculoskeletal rehabilitation
2017

TIM-3 plays a more important role than PD-1 in the functional impairments of cytotoxic T cells of malignant Schwannomas.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
2017

Surgical approach to posterior mediastinal lesions and long-term outcomes.

Asian cardiovascular &amp; thoracic annals
2017

Robotic resection of an obturator schwannoma with preservation of normal nerve fascicles and function.

Journal of robotic surgery
2017

A Lip Lump: An Unexpected Histological Diagnosis of a Lip Schwannoma.

Case reports in otolaryngology
2017

Peripheral Nerve Schwannoma: A Review of Varying Clinical Presentations and Imaging Findings.

The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
2017

Robot-Assisted Laparoscopic Resection of a Pelvic Schwannoma.

Urology case reports
2016

Schwannoma in the hepatoduodenal ligament: A case report and literature review.

World journal of gastroenterology
2016

Primary hepatic schwannoma: A case report.

International journal of surgery case reports
2016

Resection of an esophageal schwannoma with thoracoscopic surgery: a case report.

Surgical case reports
2016

[Radiation-Induced Malignant Peripheral Nerve Sheath Tumor of the High Cervical Spine].

No shinkei geka. Neurological surgery
2016

Hemorrhagic, calcified, and ossified benign retroperitoneal schwannoma: First case report.

Medicine
2016

Multiple Unilateral Vestibular Schwannomas: Segmental NF2 or Sporadic Occurrence?

Journal of neurological surgery reports
2016

[Primitive benign retrovesical schwannoma: an extremely rare tumor, a case report].

The Pan African medical journal
2016

Symptomatic pericardial schwannoma treated with video-assisted thoracic surgery: a case report.

Journal of thoracic disease
2016

Laparoscopic resection of benign schwannoma in the hepatoduodenal ligament: A case report and review of the literature.

Oncology letters
2016

Giant Schwannoma of the Saphenous Nerve in The Distal Thigh: A Case Report.

Surgical technology international
2016

Thoracic Nerve Root Schwannoma Filling the Spinal Canal Almost Entirely Without any Neurological Deficits.

Anesthesiology and pain medicine
2016

Benign schwannoma of the maxillary antrum.

European journal of dentistry
2016

Successful excision of a massive bleeding schwannoma by thoracoscopic surgery.

Asian cardiovascular &amp; thoracic annals
2016

A large schwannoma of the middle mediastinum: A case report and review of the literature.

Oncology letters
2015

Laparoscopic resection of a retroperitoneal schwannoma located in the hepatic hilus.

Surgical case reports
2016

Clinical Features and Treatment of Penile Schwannoma: A Systematic Review.

Clinical genitourinary cancer
2017

Mediastinal schwannoma with atypical localization diagnosed by endobronchial ultrasound.

The clinical respiratory journal
2015

[Two Cases of Intrapelvic Schwannoma].

Hinyokika kiyo. Acta urologica Japonica
2015

[A Case of Retroperitoneal Tumor in the Adrenal Area Turned Out to Be Schwannoma Mimicking an Adrenal Malignant Tumor].

Hinyokika kiyo. Acta urologica Japonica
2015

Surgical Planning by 3D Printing for Primary Cardiac Schwannoma Resection.

Yonsei medical journal
2015

Benign intramural schwannoma of the esophagus - case report.

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
2015

Retroperitoneal schwannoma between the inferior vena cava and the abdominal aorta resected by laparoscopic surgery: A case report.

Asian journal of endoscopic surgery
2015

Identification, by systematic RNA sequencing, of novel candidate biomarkers and therapeutic targets in human soft tissue tumors.

Laboratory investigation; a journal of technical methods and pathology
2015

A longitudinal study to assess the volumetric growth rate of spinal intradural extramedullary tumour diagnosed with schwannoma by magnetic resonance imaging.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
2015

Vestibular schwannoma atypically invading temporal bone.

Journal of Korean Neurosurgical Society
2015

An unusual case of vulvar schwannoma.

World journal of surgical oncology
2015

Laparoscopic resection of schwannoma of the ascending colon.

Case reports in gastroenterology
2015

Ancient schwannoma of the thumb pulp.

Plastic and reconstructive surgery. Global open
2015

Symptomatic schwannoma of the abdominal wall: A case report and review of the literature.

Oncology letters
2015

Retroperitoneal schwannomas: advantages of laparoscopic resection. Review of the literature and case presentation of a large paracaval benign schwannoma (with video).

Asian journal of endoscopic surgery
2015

Malignant Transformation of Vagal Nerve Schwannoma in to Angiosarcoma: A Rare Event.

Journal of surgical technique and case report

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Successful Sphincter-Preserving Resection of a Giant Rectal Schwannoma Using Transanal Total Mesorectal Excision: A Case Report.
    Surgical case reports· 2026· PMID 41809088mais citado
  2. A schwannoma of the olfactory nerve: a case report of a diagnostic challenge and review of the literature.
    Journal of surgical case reports· 2026· PMID 41694439mais citado
  3. Incidental obturator nerve schwannoma mimicking nodal disease during radical prostatectomy: Resolution of chronic neuropathic pain after intracapsular nerve-sparing excision.
    Urology case reports· 2026· PMID 41552400mais citado
  4. Scalp schwannomas as a rare entity with common misdiagnoses: A case report and systematic literature review.
    Surgical neurology international· 2025· PMID 41112367mais citado
  5. Transcriptomic analysis reveals novel targets in benign schwannoma using machine learning.
    Neuroscience· 2025· PMID 40550384mais citado
  6. Minimally Invasive Extirpation of an Eden Type II Dumbbell-Shaped Mediastinal Tumor Using a Posterior and Uniportal Thoracoscopic Approach without Changing the Patient's Position: A Case Report.
    Surg Case Rep· 2026· PMID 41913900recente
  7. A Rare Case of Benign Esophageal Schwannoma.
    Cureus· 2025· PMID 41583189recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:252164(Orphanet)
  2. MONDO:0002546(MONDO)
  3. GARD:4767(GARD (NIH))
  4. Variantes catalogadas(ClinVar)
  5. Busca completa no PubMed(PubMed)
  6. Artigo Wikipedia(Wikipedia)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Schwannoma benigno
Compêndio · Raras BR

Schwannoma benigno

ORPHA:252164 · MONDO:0002546
Prevalência
1-9 / 100 000
Herança
Not applicable
CID-10
D36.1 · Neoplasia benigna dos nervos periféricos e sistema nervoso autônomo
CID-11
Ensaios
4 ativos
Início
Adult, Elderly
Prevalência
6.0 (Europe)
MedGen
UMLS
C0027809
EuropePMC
Wikipedia
Papers 10a
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