O palato é o teto da boca dos animais vertebrados, incluindo os humanos. Ele separa a cavidade oral da cavidade nasal. O palato é dividido em duas partes, a parte óssea anterior e a parte mole posterior.
Introdução
O que você precisa saber de cara
A fenda palatina, afetando o palato mole e duro, é uma anomalia congênita que pode levar à hipoplasia maxilar, fala hipernasal, micrognatia e má oclusão dentária.
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Sinais e sintomas
O que aparece no corpo e com que frequência cada sintoma acontece
Partes do corpo afetadas
Características mais comuns
Os sintomas variam de pessoa para pessoa. Abaixo estão as 4 características clínicas mais associadas, ordenadas por frequência.
Linha do tempo da pesquisa
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Genética e causas
O que está alterado no DNA e como passa nas famílias
Nenhum gene associado encontrado
Os dados genéticos desta condição ainda estão sendo catalogados.
Diagnóstico
Os sinais que médicos procuram e os exames que confirmam
Tratamento e manejo
Remédios, cuidados de apoio e o que precisa acompanhar
Onde tratar no SUS
Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)
🇧🇷 Atendimento SUS — Fenda palato mole e duro
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Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.
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Publicações mais relevantes
Orofacial clefting in PHF6-related Börjeson-Forssman-Lehmann syndrome.
Börjeson-Forssman-Lehmann syndrome (BFLS) is a rare X-linked neurodevelopmental disorder caused by pathogenic variants in the plant homeodomain finger protein 6 (PHF6) gene. Core features include developmental delay, intellectual disability, dysmorphic craniofacial characteristics, obesity, hypogonadism and digital anomalies. Orofacial clefting has not been recognised as part of the canonical phenotype and is rarely reported in association with BFLS. One cohort study listed cleft lip and/or palate as an uncommon feature without individual case details, and a separate report described a female with a nonsense PHF6 variant and clefting of the hard and soft palate. Here, we describe a BFLS female with a de novo missense PHF6 variant who presented with cleft palate. This case adds to the emerging evidence that clefting, though uncommon, may be a recurrent manifestation. It supports the inclusion of PHF6 in the genetic testing of patients presenting with syndromic orofacial clefting when accompanied by neurodevelopmental delay or dysmorphism.
Design of Buccinator Flaps for Oronasal Fistula Repair: A Technical Review and Case Series.
Oronasal fistula (ONF) repair remains a significant challenge in patients with cleft lip and palate, particularly when local palatal tissue is insufficient. Regional flaps, including the buccal myomucosal flap (BMMF) and the facial artery musculomucosal (FAMM) flap, offer reliable reconstructive options. This study reviews the surgical anatomy, design, and clinical outcomes of these buccinator-based flaps in ONF repair. This retrospective case series included 13 patients who underwent ONF repair using a BMMF or a FAMM flap between 2017 and 2024. Patient demographics, fistula characteristics, surgical details, postoperative care, and outcomes were collected and analyzed. Six patients underwent BMMF reconstruction, while 7 received FAMM flaps. Successful fistula closure was achieved in 66.7% of patients in the BMMF group, with flap dehiscence occurring in 2 cases, both associated with digital manipulation. The FAMM flap cohort had a 100% fistula closure rate but exhibited a high incidence (86%) of postoperative scar contracture, with 4 patients requiring contracture release. Based on this experience, the authors propose an algorithm for flap selection in ONF repair. Posteriorly based BMMFs are well suited for fistulas at the junction of the hard and soft palate (Type III) and the posterior third of the hard palate (Type IV). Superiorly based FAMM flaps are preferred for anterior ONFs, particularly those extending into the alveolus. The central hard palate remains a reconstructive challenge, with FAMM flaps offering better reach, though they require staged inset and debulking. Both BMMF and FAMM flaps provide vascularized tissue for ONF closure with minimal donor site morbidity. Strategic flap selection based on fistula location optimizes outcomes while mitigating complications.
Minor modification of soft palate surgical technique resulted in a considerable increase of residual cleft dimensions for unilateral cleft lip and palate.
A two-stage surgical approach, starting with the soft palate, has been practiced in the Gothenburg cleft team for unilateral cleft lip and palate (UCLP) since decades. To improve the velopharyngeal function, a modified soft palate closure (SPC) technique was introduced. Clinical observations did however indicate that the novel technique resulted in a deviant residual cleft shape, potentially contributing to future compromised dental arch form. This study aimed to compare residual cleft dimensions (area, width and length) between different SPC techniques and at various age, in individuals born with UCLP. Material and methods: The sample consisted of three groups of children with non-syndromic UCLP: 1. 27 individuals who had original SPC and hard palate closure (HPC) at 3 years (GBG3) 2. 37 individuals who had a modified SPC and HPC at 2 years (GBGmod) 3. 29 individuals who had original SPC and HPC at 2 years (GBG2). Residual cleft area, length and width were measured on digitised cast models using Blender software. Multiple linear regression analysis was used to compare the groups. Larger residual cleft dimensions (area and length) were found for GBGmod compared to both GBG3 (p < 0.001, p = 0.009) and GBG2 (p = 0.009, p = 0.009). In addition, GBGmod had increased cleft width in comparison with GBG3 and GBG2 in quartile 1. The modified SPC technique resulted in larger residual clefts in comparison with the groups operated with the original SPC method. Timing differences between GBG3 and GBG2 are likely one explanation of cleft width variations anteriorly.
Doble Aligner Nasoalveolar Molding: A New Approach of Digital Protocol for Cleft Lip and Palate in Newborn Patients.
In Spain, a new digital workflow protocol has been developed for patients with cleft lip and palate. This protocol involves several steps, including the creation of a double aligner tray for nasoalveolar molding (2A-NAM) and the utilization of digital intraoral scans for the movement design. The sequential process includes: intraoral scanning (IOS), virtual design (VD), digital impression (DI), 2A-NAM preparation, and analysis of anatomical changes. This process is repeated until the desired outcomes are achieved. At just 7 days of age, records of the male child were obtained using an iTero® Element 5D intraoral laser scanner. Additionally, an extraoral record was taken to measure the distance from the commissure to the left nostril, which enables the reconstruction of the nasal stent of the tray. The resulting stereolithography (STL) files underwent digital planification using 3D NemoStudio. The degree of approximation, rotation, and inclination of major and minor segments varied for each (M) based on each individual record and the patient's specific condition. Finally, the Form 3+® 3D-printer was used to produce the VD using Formlabs® photopolymer resin. The technician then assembled the device using a Durasoft® PD splint (both hard and soft components), to which tension springs were added using wire and secured with resin. A total of five 2A-NAMs were required to achieve proper segment approximation prior to orthopedic surgery at 4.5 months of age. By assessing the anatomical predictions provided by digital simulation, clinicians can make proper decisions regarding the approximation of the maxillary segments of the patient. The predictability of planned approximation movements and the absence of aligner injuries motivate the promotion of the protocol as a reliable method that facilitates pediatric dentistry and orthodontic treatment for any professional, ensuring patient safety. Rico-Lillo I, García-García VJ, Kasem K, et al. Doble Aligner Nasoalveolar Molding: A New Approach of Digital Protocol for Cleft Lip and Palate in Newborn Patients. Int J Clin Pediatr Dent 2026;19(1):110-119.
Comparative analysis of soft tissue response after orthognathic surgery in patients with and without cleft using 3D imaging: A preliminary study.
This study investigated differences in upper lip soft tissue response to skeletal movement between patients with and without cleft following orthognathic surgery. Twelve patients with Class III dentofacial deformities underwent orthognathic surgery: six with complete unilateral cleft lip and palate and six age- and sex-matched non-cleft controls. Hard tissue movement was measured using 3D surgical simulation, and soft tissue changes were assessed with 3D photogrammetry. The cleft group showed significantly greater advancement across all hard tissue landmarks compared to the non-cleft group (p < 0.01). However, soft tissue advancement at the subnasale was only moderately greater in the cleft group (p < 0.05), with no significant differences observed at other midline points. Soft-to-hard tissue movement ratios were consistently lower in the cleft group, although these differences did not reach statistical significance. The ratio of soft tissue volume change to A-point displacement was higher in the non-cleft group than in the cleft group (p < 0.05), indicating a reduced soft tissue response in the cleft group. These findings suggest that patients with cleft may require greater skeletal advancement to achieve favorable soft tissue outcomes, highlighting the importance of individualized surgical planning to balance aesthetic goals with complications such as velopharyngeal insufficiency.
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📚 EuropePMCmostrando 199
Design of Buccinator Flaps for Oronasal Fistula Repair: A Technical Review and Case Series.
EplastyOrofacial clefting in PHF6-related Börjeson-Forssman-Lehmann syndrome.
BMJ case reportsMinor modification of soft palate surgical technique resulted in a considerable increase of residual cleft dimensions for unilateral cleft lip and palate.
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The Journal of craniofacial surgerySpeech Symptoms of Velopharyngeal Insufficiency and the Incidence of Secondary Speech Surgery in 10-Year-Old Children With Unilateral Cleft Lip and Palate: Comparison of 2 Randomized Surgical Methods for Primary Palatal Surgery.
The Journal of craniofacial surgeryCleft Palate in Apert Syndrome.
Journal of developmental biologySix-year post-surgical evaluation in the treatment protocols in the dental arches of children with oral cleft: longitudinal study.
Journal of applied oral science : revista FOBImpact of a Palatal Fistula After Cleft Palate Repair on Velopharyngeal Closure.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationNovel de novo missense mutation in the interferon regulatory factor 6 gene in an Italian infant with IRF6-related disorder.
Italian journal of pediatricsIs the Message Clear? Evaluation of Readability Levels for Cleft Lip, Cleft Palate, and Craniofacial Websites.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationPleomorphic Adenoma of the Palate: A Rare Case in an Adolescent With Cleft lip and Palate.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationDifferences in Practice in Alveolar Bone Grafting Among American Cleft Palate-Craniofacial Association Members.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationThe First Hybrid International Educational Comprehensive Cleft Care Workshop.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationOcclusal Evaluation Using Modified Huddart and Bodenham Scoring System Following 2-Stage Palatoplasty With Hotz Plate: A Comparison Among 3 Different Surgical Protocols.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationSurgically treated congenital cleft palate in a 4-month-old kitten: medium-term clinical and CT assessment.
JFMS open reportsTriple Layer Oronasal Fistula Repair Using Local Endonasal Flaps: Case Series of Three Patients.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationPrognosis of otitis media with effusion in pediatric patients with cleft palate during language-acquisition period treated by simultaneous tympanostomy tube placement with palatoplasty.
International journal of pediatric otorhinolaryngologyCurrent Surgical Practice for Children Born with a Cleft lip and/or Palate in the United Kingdom.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationA predictor of a postoperative fistula after double-opposing Z-plasty in bilateral cleft lip and palate patients.
Journal of plastic, reconstructive & aesthetic surgery : JPRASSimultaneous Closure of the Cleft Alveolus and Hard Palate with Concomitant Bone Grafting.
Plastic and reconstructive surgery. Global openNovel approach for treating challenging implant-borne maxillary dental rehabilitation cases of cleft lip and palate: a retrospective study.
International journal of implant dentistryIncidence of fistula after primary cleft palate repair: a 25-year assessment of one surgeon's experience.
Archives of plastic surgeryCadaveric Study and Micro-Computed Tomography of the Anatomy of Palatine Aponeurosis and its Link to the Soft Palate Muscles and Pharyngeal Muscles.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationTissue Augmenting Palatoplasty for the Treatment of Velopharyngeal Insufficiency.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationCephalometric Analysis of Hard and Soft Tissue Changes Following Anterior Maxillary Osteotomy Distraction in Cleft Maxillary Hypoplasia.
Journal of maxillofacial and oral surgeryFive-year prospective fistula audit in a single center. TIG training negates consultant learning curve, but surgeons should beware the mid-range palatal defect.
Journal of plastic, reconstructive & aesthetic surgery : JPRASThe Smile Index: Part 3. A Simple, Prognostic Severity Scale for Unilateral Cleft Palate.
Plastic and reconstructive surgery. Global openThe Application of Buccal Fat Pad to Cover Lateral Palatal Defect Causes Early Mucolization.
CureusNoggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling.
Frontiers in cell and developmental biologyCharacterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre-Robin sequence.
Korean journal of orthodonticsComplications During Grayson Presurgical Nasoalveolar Molding Method in Nonsyndromic Infants With Complete Unilateral Cleft Lip and Palate.
The Journal of craniofacial surgeryUse of a buccinator myomucosal flap and bilateral pedicled buccal fat pad transfer in wide palatal fistula repair: a case report.
Archives of craniofacial surgeryEctomesenchymal Chondromyxoid Tumor: A Rare Association With an Asymmetrical Soft Palate Cleft.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationThree-Dimensional Anatomy of the Palatopharyngeus and Its Relation to the Levator Veli Palatini Based on Micro-Computed Tomography.
Plastic and reconstructive surgeryNasal asymmetry changes during growth and development in 6- to 12-year-old children with repaired unilateral cleft lip and palate: A 3D computed tomography analysis.
Journal of anatomyContinuous Multidisciplinary Care for Patients With Orofacial Clefts-Should the Follow-up Interval Depend on the Cleft Entity?
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationQuantitative Evaluation of Palatal Lengthening After Cleft Palate Repair When a Buccal Flap Is Routinely Combined With Furlow's Z-Plasty.
Annals of plastic surgerySpeech Outcome and Self-Reported Communicative Ability in Young Adults Born With Unilateral Cleft Lip and Palate: Comparing Long-Term Results After 2 Different Surgical Methods for Palatal Repair.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationEarly Communication Behaviors in Infants With Cleft Palate With and Without Robin Sequence: A Preliminary Study.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationAn Observational Study to Evaluate Association Between Velopharyngeal Anatomy and Speech Outcomes in Adult Patients With Severe Velopharyngeal Insufficiency.
The Journal of craniofacial surgeryTessier 30 Facial Clefts-A Literature Review of 72 Cases (1996-2020), Suggested Treatment Protocol, Outcome Measures, Minimum Dataset for Future Case Reports, and Registries.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationThree-Dimensional Facial Soft Tissue Changes After Orthognathic Surgery in Cleft Patients Using Artificial Intelligence-Assisted Landmark Autodigitization.
The Journal of craniofacial surgeryCharacteristics of craniofacial morphology and factors affecting them in patients with isolated cleft palate.
PeerJA Preliminary Study of Anatomical Changes Following the Use of a Pedicled Buccal Fat Pad Flap During Primary Palatoplasty.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationCleft Lip and/or Palate in Infants Prenatally Exposed to Opioids.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationDental Arch Relationship Outcomes Following 2-Stage Palatoplasty for Japanese Patients With Complete Unilateral Cleft Lip and Palate: A 3-Center Study.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationCheek soft tissue prediction in cleft orthognathic surgery: A 3D computer-assisted investigation with comparative analysis.
Journal of plastic, reconstructive & aesthetic surgery : JPRASImpairment in facial expression generation in patients with repaired unilateral cleft lip: Effects of the physical properties of facial soft tissues.
PloS oneEvaluation of masticatory function in patients with cleft lip and/or palate.
European journal of oral sciencesPrimary Palatal Surgery in Nonsyndromic Cleft Palate Children and Velopharyngeal Insufficiency Correction Outcomes.
The Journal of craniofacial surgeryEvaluation of fistula rates in three cleft palate techniques without relaxing incisions.
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial SurgerySpeech and Audiology Outcomes After Single-Stage Versus Early 2-Stage Cleft Palate Repair.
Annals of plastic surgeryA novel modification of Bardach's two-flap palatoplasty for the repair of a difficult cleft palate.
Archives of plastic surgeryRegistry-Based Study of Prevalence of Cleft Lip/Palate in Thailand from 2012 to 2015.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationCAD/CAM Engineered Patient-Specific Impants as a Reposition Device in Le Fort I and Modified Subcondylar Osteotomies: Case Report of Facial Deformity Correction in Acromegaly.
Craniomaxillofacial trauma & reconstructionSoft Palate Fistula in a Patient With Normal Palate as a Rare Complication After Septoplasty.
The Journal of craniofacial surgeryOrthodontic Management of a Palatal Fistula in a Patient With Pierre Robin Sequence Using 3D Intraoral Scanning and Computer-Aided Design.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationIncidence of Symptomatic Submucous Cleft Palate in the Netherlands: A Retrospective Cohort Study Over a Period of 22 Years.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationA Cadaveric Study of the Buccal Fat Pad: Implications for Closure of Palatal Fistulae and Donor-Site Morbidity.
Plastic and reconstructive surgeryA Pitfall in Prenatal Ultrasonic Detection of Submucous Cleft Palate.
Ear, nose, & throat journalSurgical Reconstruction of Cocaine-Induced Cleft Lip: A Case Report.
The Permanente journalAn Evaluation of Wound Healing Efficacy of a Film Dressing Made from Polymer-integrated Amnion Membrane.
OrganogenesisA Global Evaluation of Surgical Techniques and Results of Unilateral Cleft Lip Repairs.
The Journal of craniofacial surgeryStem Cells Regenerating the Craniofacial Skeleton: Current State-Of-The-Art and Future Directions.
Journal of clinical medicineThe Effect of Surgical Timing on 30-Day Outcomes in Cleft Palate Repair.
Plastic and reconstructive surgeryA new two-dimensional sonographic approach to the assessment of the fetal hard and soft palates.
Journal of clinical ultrasound : JCUSimulation Surgery Using 3D 3-layer Models for Congenital Anomaly.
Plastic and reconstructive surgery. Global openAssessment of the New L Pharyngeal Flap for Velopharyngeal Insufficiency.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationA Toolbox of Surgical Techniques for Palatal Fistula Repair.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationFor Patients With Isolated Cleft Palate Does Revision Palatoplasty Have an Increased Risk of Inpatient Complication Compared to Primary Palatal Repair?
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationBuccal fat pad in cleft palate repair- An institutional experience of 27 cases.
International journal of pediatric otorhinolaryngologyTechniques and results of palate fistula repair following palatoplasty: a 234-case multicenter study.
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia PediatricaAndrew's bridge system: A boon for huge ridge defect in aesthetic zone.
Journal of oral biology and craniofacial researchProspective evaluation of the effect of early nasal layer closure on definitive repair in cleft palate patients.
Brazilian journal of otorhinolaryngologyReceptive and Expressive Vocabulary Skills and Their Correlates in Mandarin-Speaking Infants with Unrepaired Cleft Lip and/or Palate.
International journal of environmental research and public healthMaxillary protraction in patients with unilateral cleft lip and palate : Evaluation of soft and hard tissues using the Alt-RAMEC protocol.
Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie[Palatal fistula rate after Huaxi Sommerlad-Furlow palatoplasty].
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatologySpeech of Patients With Unilateral Complete Cleft Lip and Palate: Comparison of Three Different Surgical Protocols for Primary Repair.
The Journal of craniofacial surgeryTemporal Muscle Flap as a Treatment of an Extensive Cleft Palate in an Adult Patient.
The Journal of craniofacial surgeryAlexis Retractor: Institutional Experience of Its Applications in Head and Neck Surgery and Review of the Literature.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationAn Intraoperative Salvage After Transection of the Greater Palatine Artery During Cleft Palate Repair: A Case for Buccal Fat and Buccal Myomucosal Flaps.
The Journal of craniofacial surgeryScandcleft Project Trial 3: Comparison of Speech Outcomes in Relation to Sequence in 2-Stage Palatal Repair Procedures in 5-Year-Olds With Unilateral Cleft Lip and Palate.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationOcclusion at 5 Years of Age Following Hard Palate Closure With Vestibular Flap.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationScandcleft Project Trial 2-Comparison of Speech Outcome in 1- and 2-Stage Palatal Closure in 5-Year-Olds With UCLP.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationLongitudinal study of the development of obstruent correctness from ages 3 to 5 years in 108 Danish children with unilateral cleft lip and palate: a sub-study within a multicentre randomized controlled trial.
International journal of language & communication disordersWound Complications, Additional Ventilation Requirement, Prolonged Stay, and Readmission in Primary Palatoplasty: A Risk Factor Analysis of 3616 Patients.
Plastic and reconstructive surgeryRange and timing of surgery, and surgical sequences used, in primary repair of complete unilateral cleft lip and palate: The Cleft Care UK study.
Orthodontics & craniofacial researchDo Infant Cleft Dimensions Have an Influence on Occlusal Relations? A Subgroup Analysis Within an RCT of Primary Surgery in Patients With Unilateral Cleft Lip and Palate.
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial AssociationDynamic activation of Wnt, Fgf, and Hh signaling during soft palate development.
PloS oneScandcleft randomized trials of primary surgery for unilateral cleft lip and palate: maxillary growth at eight years of age.
European journal of orthodonticsAssociações
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Referências e fontes
Bases de dados externas citadas neste artigo
Publicações científicas
Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.
- Orofacial clefting in PHF6-related Börjeson-Forssman-Lehmann syndrome.
- Design of Buccinator Flaps for Oronasal Fistula Repair: A Technical Review and Case Series.
- Minor modification of soft palate surgical technique resulted in a considerable increase of residual cleft dimensions for unilateral cleft lip and palate.
- Doble Aligner Nasoalveolar Molding: A New Approach of Digital Protocol for Cleft Lip and Palate in Newborn Patients.
- Comparative analysis of soft tissue response after orthognathic surgery in patients with and without cleft using 3D imaging: A preliminary study.Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery· 2026· PMID 41546919mais citado
- Mast cell mediators in hereditary angioedema.
- Prenatal Molecular Diagnosis of COL2A1-Associated Stickler Syndrome: Genotype-Phenotype Correlation in a Resource-Limited Healthcare Setting.
- Platelet gene signatures detecting pulmonary artery stenosis in patients with pulmonary hypertension.
- The global impact of imiglucerase therapy in children with Gaucher disease types 1 and 3: a real-world analysis from the International Collaborative Gaucher Group Gaucher Registry.
- Monogenic lupus with SLC7A7 mutations: a retrospective study from a Chinese center.
Bases de dados e fontes oficiais
Identificadores e referências canônicas usadas para montar este verbete.
- ORPHA:664372(Orphanet)
- MONDO:0971092(MONDO)
- Busca completa no PubMed(PubMed)
- Artigo Wikipedia(Wikipedia)
Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.
Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar
