Raras
Buscar doenças, sintomas, genes...
Amiotrofia neurálgica
ORPHA:2901CID-10 · G54.5CID-11 · 8B91.0DOENÇA RARA

A amiotrofia nevrálgica (AN) é um distúrbio incomum do sistema nervoso periférico, caracterizado pelo início súbito de dor extrema na extremidade superior, seguida por rápida fraqueza motora multifocal e atrofia e uma recuperação lenta em meses a anos. NA inclui uma forma idiopática (INA, também conhecida como síndrome de Parsonage-Turner) e hereditária (HNA).

Mantido por Agente Raras·Colaborar como especialista →

Introdução

O que você precisa saber de cara

📋

A amiotrofia nevrálgica (AN) é um distúrbio incomum do sistema nervoso periférico, caracterizado pelo início súbito de dor extrema na extremidade superior, seguida por rápida fraqueza motora multifocal e atrofia e uma recuperação lenta em meses a anos. NA inclui uma forma idiopática (INA, também conhecida como síndrome de Parsonage-Turner) e hereditária (HNA).

Publicações científicas
681 artigos
Último publicado: 2026 Apr

Escala de raridade

CLASSIFICAÇÃO ORPHANET · BRASIL 2024
1-5 / 10 000
Ultra-rara
<1/50k
Muito rara
1/20k
Rara
1/10k
Pouco freq.
1/5k
Incomum
1/2k
Prevalência
0.0
Europe
Início
Adult
🏥
SUS: Cobertura mínimaScore: 15%
CID-10: G54.5
🇧🇷Dados SUS / DATASUS
PROCEDIMENTOS SIGTAP (2)
0202010694
Sequenciamento completo do exoma (WES)genetic_test
0301070040
Atendimento em reabilitação — doenças rarasrehabilitation
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Entender a doença

Do básico ao detalhe, leia no seu ritmo

Preparando trilha educativa...

Sinais e sintomas

O que aparece no corpo e com que frequência cada sintoma acontece

Partes do corpo afetadas

🦴
Ossos e articulações
4 sintomas
😀
Face
3 sintomas
🧠
Neurológico
2 sintomas
🫁
Pulmão
1 sintomas
💪
Músculos
1 sintomas
🧬
Pele e cabelo
1 sintomas

+ 12 sintomas em outras categorias

Características mais comuns

90%prev.
Dor em membro superior
Muito frequente (99-80%)
90%prev.
Artralgia
Muito frequente (99-80%)
90%prev.
Fraqueza muscular de membro superior
Muito frequente (99-80%)
90%prev.
Polineuropatia
Muito frequente (99-80%)
90%prev.
Anormalidade no EMG
Muito frequente (99-80%)
90%prev.
Amiotrofia do membro superior
Muito frequente (99-80%)
24sintomas
Muito frequente (6)
Frequente (3)
Ocasional (15)

Os sintomas variam de pessoa para pessoa. Abaixo estão as 24 características clínicas mais associadas, ordenadas por frequência.

Dor em membro superiorUpper limb pain
Muito frequente (99-80%)90%
ArtralgiaArthralgia
Muito frequente (99-80%)90%
Fraqueza muscular de membro superiorUpper limb muscle weakness
Muito frequente (99-80%)90%
PolineuropatiaPolyneuropathy
Muito frequente (99-80%)90%
Anormalidade no EMGEMG abnormality
Muito frequente (99-80%)90%

Linha do tempo da pesquisa

Publicações por ano — veja quando o interesse científico cresceu
Anos de pesquisa1desde 2026
Total histórico681PubMed
Últimos 10 anos200publicações
Pico202243 papers
Linha do tempo
2026Hoje · 2026🧪 2003Primeiro ensaio clínico📈 2022Ano de pico
Publicações por ano (últimos 10 anos)

Encontrou um erro ou informação desatualizada? Sugira uma correção →

Genética e causas

O que está alterado no DNA e como passa nas famílias

Genes associados

1 gene identificado com associação a esta condição. Padrão de herança: Autosomal dominant, Not applicable.

SEPTIN9Septin-9Major susceptibility factor inAltamente restrito
FUNÇÃO

Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri

LOCALIZAÇÃO

Cytoplasm, cytoskeleton

OUTRAS DOENÇAS (2)
amyotrophic neuralgianeuralgic amyotrophy
HGNC:7323UniProt:Q9UHD8

Variantes genéticas (ClinVar)

48 variantes patogênicas registradas no ClinVar.

🧬 SEPTIN9: NM_001113491.2(SEPTIN9):c.1477-33A>G ()
🧬 SEPTIN9: NM_001113491.2(SEPTIN9):c.77-28769C>T ()
🧬 SEPTIN9: NM_001113491.2(SEPTIN9):c.19G>C (p.Gly7Arg) ()
🧬 SEPTIN9: GRCh37/hg19 17q24.3-25.3(chr17:70161447-81041938)x3 ()
🧬 SEPTIN9: NM_001113491.2(SEPTIN9):c.502C>G (p.Pro168Ala) ()
Ver todas no ClinVar

Classificação de variantes (ClinVar)

Distribuição de 1 variantes classificadas pelo ClinVar.

1
Patogênica (100.0%)
VARIANTES MAIS SIGNIFICATIVAS
SEPTIN9: NM_001113491.2(SEPTIN9):c.722-6465C>T [Conflicting classifications of pathogenicity]

Diagnóstico

Os sinais que médicos procuram e os exames que confirmam

Carregando...

Tratamento e manejo

Remédios, cuidados de apoio e o que precisa acompanhar

Pipeline de tratamentos
Pipeline regulatório — de medicamentos já aprovados a drogas em pesquisa exploratória.
·Pré-clínico1
Medicamentos catalogadosEnsaios clínicos· 0 medicamentos · 1 ensaio
Carregando informações de tratamento...

Onde tratar no SUS

Hospitais de referência no Brasil e o protocolo oficial do SUS (PCDT)

🇧🇷 Atendimento SUS — Amiotrofia neurálgica

🗺️

Selecione um estado ou use sua localização para ver resultados.

Dados de DATASUS/CNES, SBGM, ABNeuro e Ministério da Saúde. Sempre confirme a disponibilidade diretamente com o estabelecimento.

Pesquisa ativa

Ensaios clínicos abertos e novidades científicas recentes

Pesquisa e ensaios clínicos

15 ensaios clínicos encontrados.

Distribuição por fase
Ver todos no ClinicalTrials.gov
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Publicações mais relevantes

Timeline de publicações
370 papers (10 anos)
#1

Clinical characteristics and results after conservative treatment or interfascicular neurolysis of 58 limbs with spontaneous posterior interosseous nerve palsy: A prospective Japanese multicenter study.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association2026 Mar 07

Spontaneous posterior interosseous nerve (PIN) palsy is a rare condition with controversial clinical features. Although this palsy is conventionally treated conservatively, interfascicular neurolysis to release hourglass-like fascicular constrictions has also been recommended. This study aimed to clarify the clinical characteristics and treatment guidelines for this palsy. Fifty-eight limbs with spontaneous PIN palsy receiving conservative treatment or interfascicular neurolysis. The presence of pain as a premonitory symptom and the degree of muscle weakness were investigated. Patients were followed periodically from 3 months after palsy onset to either recovery or ≥36 months afterwards. Limbs recovering to manual muscle testing (MMT) grade 4 or better for both the extensor pollicis longus and extensor digitorum were rated as Good recovery, with all others judged as Poor. Good recovery was achieved in 31 of 34 limbs treated conservatively and 19 of 24 of limbs by interfascicular neurolysis. Younger age at onset was the factor significantly associated with achieving Good recovery in 58 limbs treated by conservatively or interfascicular neurolysis. In the 24 limbs treated by interfascicular neurolysis, early timing of surgery was the factor significantly associated with attaining Good recovery. All 27 limbs with conservative treatment displaying ≥1 grade of MMT improvement within 6 months after onset achieved Good recovery. In the 23 limbs with Poor recovery at 6 months by conservative treatment, Good recovery was attained in 4 of 7 limbs by continuing conservative treatment and in 12 of 16 limbs by subsequent interfascicular neurolysis. Although the latter treatment tended to produce better results, no significant difference was detected. Diverse clinical characteristics of spontaneous PIN palsy are useful for diagnosis. Conservative treatment is advisable within 6 months after onset of palsy. If no improvement is observed, interfascicular neurolysis without delay is a reasonable option.

#2

Clinical characteristics of hospitalized patients with hepatitis E virus infection in Poland: a multi-centre retrospective study.

Advances in medical sciences2026 Feb 24

The burden of hepatitis E virus (HEV) infections in Poland is highly underestimated and in contrast with high anti-HEV IgG seroprevalence in Polish population. This is the first publication addressing the issues of HEV infections in Poland as well as surveillance and reporting problems referring to this particular disease. In this retrospective study we analysed 61 HEV cases referred to and diagnosed in 10 leading centres in Poland. Males constituted 70.5% of the study group, with equal distribution of cases below and over 50 years of age. Comorbidities were reported in 73.8% of this group. Of major concern was the high frequency of reported complications and clinical outcomes: 3 cases of acute liver failure (ALF) with 1 resulting in orthotopic liver transplantation (OLTx), 1 case of renal insufficiency, 3 cases of neuralgic amyotrophy, 8 cases of thromocytopaenia, and 4 cases of chronic hepatitis E. The HEV infections in Poland are considerably underestimated, which results both from the lack of awareness of general practitioners and limited access to HEV diagnostics, particularly in primary and secondary care medical facilities in Poland.

#3

Isolated phrenic neuropathy in neuralgic amyotrophy.

Practical neurology2026 Feb 27
#4

Pre-Plexal Extension of Parsonage-Turner Syndrome With Nerve Root Involvement on Needle Electromyography.

Journal of clinical neuromuscular disease2026 Mar 01

Parsonage-Turner syndrome (PTS) is an inflammatory, immune-mediated neurogenic condition characterized by acute-onset, severe unilateral shoulder/upper arm pain followed by patchy weakness and atrophy. Often described as an idiopathic brachial plexitis, most cases of PTS involve the brachial plexus or its terminal branches, and root-level or paraspinal muscle involvement is rare. Among the differential diagnoses for proximal neuropathic root involvement, cervical radiculopathy by mechanical compression of the exiting nerve roots and diabetic cervical radiculoplexus neuropathy by way of immune-mediated microvasculitis, ischemic injury, and subsequent ischemic axonal damage should be considered. The latter also shares similar symptomatology to PTS with progression with subacute, painful, asymmetric involvement of the upper limb followed by atrophy and weakness of the limb. Here, we present a case of PTS with notable findings of cervical paraspinal muscle involvement on needle electromyography, highlighting a rare proximal, pre-plexal extension of this idiopathic inflammatory immune process.

#5

Neuralgic amyotrophy: Incidence, specialty of diagnosing clinician, and delays in treatment.

Hand surgery &amp; rehabilitation2026 Feb 05

This study sought to determine the incidence of Neuralgic Amyotrophy (NA) in the United States of America's health system, most common presenting symptoms, time from symptom onset and time from initial presentation to diagnosis, number and specialty of clinicians seen prior to diagnosis, and specialty of diagnosing clinician. A retrospective chart review study was conducted to identify all patients diagnosed with ICD-10 G54.5 from September 1, 2016-December 31, 2023. 153 patients with NA diagnoses from 2016 to 2023 were included. The average incidence of NA in the United States of America's healthcare system was 1.77/100,000 per year. The most common chief concern upon presentation was shoulder pain, (n = 57, 37.2%) and the most common secondary or tertiary concern was shoulder weakness (n = 41, 26.7%). Average time from symptom onset to diagnosis was 101.3 days (SD = 155.4; median = 51 days), and from initial presentation to diagnosis was 78.1 days (SD = 145.6; median = 28 days). Sixty-three patients (41.2%) presented to one other clinician with similar symptoms prior to diagnosis, 37 (24.2%) saw two clinicians, 16 (10.5%) saw three, and 7 (4.6%) saw four or more clinicians. Patients most often initially presented to a family medicine, primary care, or urgent care clinician (n = 61, 39.9%). The most common specialties of diagnosing clinicians were orthopaedic surgery (100 diagnoses, 65.4%), neurology (23 diagnoses, 15%) and neurosurgery (15 diagnoses, 10%). Diagnosis of neuralgic amyotrophy is historically rare, but the incidence may be higher than previously thought. Neuralgic amyotrophy is a debilitating disorder that is often initially unrecognized, ultimately leading to a months-long delay in diagnosis. Over 80% of patients were seen by at least one other clinician before diagnosis, and orthopaedic clinicians were most likely to make the diagnosis. Maintaining a high clinical suspicion while recognizing the common presenting symptoms along with onset and evolution of symptoms would help facilitate timely referral to specialists trained in identifying and managing neuralgic amyotrophy, prevent unnecessary and unproductive appointments preceding the diagnosis, and allow earlier initiation of treatment. Diagnostic Type IV.

Publicações recentes

Ver todas no PubMed

📚 EuropePMC400 artigos no totalmostrando 193

2026

Clinical characteristics and results after conservative treatment or interfascicular neurolysis of 58 limbs with spontaneous posterior interosseous nerve palsy: A prospective Japanese multicenter study.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
2026

A Rare Case of Neuralgic Amyotrophy Involving the Tibial Nerve Following Otologic Surgery.

Journal of otology
2026

Pre-Plexal Extension of Parsonage-Turner Syndrome With Nerve Root Involvement on Needle Electromyography.

Journal of clinical neuromuscular disease
2026

Isolated phrenic neuropathy in neuralgic amyotrophy.

Practical neurology
2026

Clinical characteristics of hospitalized patients with hepatitis E virus infection in Poland: a multi-centre retrospective study.

Advances in medical sciences
2026

Neuralgic amyotrophy: Incidence, specialty of diagnosing clinician, and delays in treatment.

Hand surgery &amp; rehabilitation
2026

The surgical treatment of Parsonage-Turner Syndrome: A PRISMA scoping review.

Neurosurgical review
2026

Radial Mononeuropathy: Clinical and Electrodiagnostic Characteristics in 177 Patients.

Muscle &amp; nerve
2025

The role of ultrasonography of the brachial plexus in differentiating between Parsonage-Turner syndrome and neuroborreliosis. A pictorial review.

Polish journal of radiology
2026

Epidemiology of Neuralgic Amyotrophy-A Retrospective Analysis of Data From a Large German Health Insurance Company.

Muscle &amp; nerve
2025

Parsonage-Turner Syndrome: An Unusual Cause of Postoperative Complications.

Cureus
2025

Hourglass-Like Constriction of the Brachial Plexus in an Adult Patient: A Case Report.

Neurosurgery practice
2025

Hepatitis E infection complicated by bilateral neuralgic amyotrophy and phrenic nerve palsy: a case report.

Acta gastro-enterologica Belgica
2025

Septins in the nervous system: from cytoskeletal dynamics to neurological disorders.

Cell communication and signaling : CCS
2025

Serum Neurofilament Light Chain Level as an Indicator of Axonal Injury in Parsonage-Turner Syndrome (Neuralgic Amyotrophy).

Journal of the peripheral nervous system : JPNS
2025

Patients with Neuralgic Amyotrophy Commonly Visit the Emergency Department Without Receiving a Correct Diagnosis.

Next research
2025

Case Report: Parsonage-Turner syndrome due to SEPTIN9 mutation: report of an Italian family with childhood onset and review of the literature.

Frontiers in pediatrics
2025

Incidence of backpack palsy and neuralgic amyotrophy in the Dutch military population.

BMJ neurology open
2025

Parsonage-Turner Syndrome Following COVID-19 Exposures: A Systematic Review.

Hand (New York, N.Y.)
2025

Preliminary experiences in diagnosing and treating neuralgic amyotrophy with ulnar nerve involvement often misdiagnosed as cubital tunnel syndrome.

Quantitative imaging in medicine and surgery
2025

Parsonage-Turner Syndrome After Bacterial Pharyngitis in Childhood With Resulting Glenohumeral Joint Subluxation in Adulthood.

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
2025

Neurological Manifestations of HEV Infection: A Rare Phenomenon or an Underrecognized Reality?

Brain and behavior
2025

Post-Transplant Pain and Paralysis: Neurologic Amyotrophy as an Atypical Cause of Shoulder Dysfunction Following Hematopoietic Stem Cell Transplant.

Cancers
2025

Nerve ultrasound in the diagnosis of inflammatory neuropathies.

Current opinion in neurology
2025

Isolated Pectoralis Major and Tricep Atrophy Secondary to Neuralgic Amyotrophy.

Cureus
2025

Concomitant Ipsilateral Hourglass-Like Constrictions of Suprascapular and Axillary Nerves: Report of a Rare Case.

The journal of hand surgery Asian-Pacific volume
2025

Brachial plexus neuromuscular ultrasound in neuralgic amyotrophy.

BMJ case reports
2025

Functional Restoring in Parsonage-Turner Syndrome With a Multimodal Rehabilitation Program: A Case Report.

Cureus
2025

Convergence of Infection, Chimeric Antigen Receptor T-Cell Therapy, and Neuralgic Amyotrophy: A Case Report.

American journal of physical medicine &amp; rehabilitation
2025

[Therapeutic options in patients with neuralgic amyotrophy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
2025

Bilateral Diaphragmatic Paralysis Requiring Non-Invasive Ventilatory Support as a Consequence of Hepatitis E Virus-Associated Neuralgic Amyotrophy.

Open respiratory archives
2025

Neuromuscular Ultrasound Identification of Musculocutaneous Fasciculopathies in Neuralgic Amyotrophy.

Journal of clinical neuromuscular disease
2025

Unusual delayed and prolonged arm weakness and atrophy following botulinum toxin injection for musician's cramp: case report.

Journal of neural transmission (Vienna, Austria : 1996)
2025

A case of neuralgic amyotrophy presenting with multiple lower cranial neuropathies with delayed onset of symptoms.

PM &amp; R : the journal of injury, function, and rehabilitation
2025

Neuralgic amyotrophy of Parsonage and Turner in daily practice: More often mononeuropathic than previously assumed.

Joint bone spine
2024

Parsonage-Turner Syndrome and Occupational Therapy Interventions: A Case Report.

Cureus
2025

Hourglass-like constriction is a hallmark of neuralgic amyotrophy (Parsonage-Turner syndrome).

Hand surgery &amp; rehabilitation
2025

Tofersen treatment leads to sustained stabilization of disease in SOD1 ALS in a "real-world" setting.

Annals of clinical and translational neurology
2024

Neuralgic amyotrophy with hourglass-like constrictions: A case report.

World journal of clinical cases
2024

Parsonage-Turner-syndrome associated with Mycoplasma pneumoniae infection.

Respirology case reports
2024

High-resolution Ultrasound of Peripheral Nerve Disorders.

Seminars in musculoskeletal radiology
2024

Modeling extrahepatic hepatitis E virus infection in induced human primary neurons.

Proceedings of the National Academy of Sciences of the United States of America
2025

Determining the degree of proximal nerve fascicle rotation in healthy controls using ultrahigh-frequency neuromuscular ultrasound: A pilot study.

Muscle &amp; nerve
2024

Early aggressive constriction resection for hourglass-like constriction of peripheral nerve in the upper extremity: a retrospective study.

Neuro-Chirurgie
2025

The Role of Neuromuscular Ultrasound in the Diagnosis of Peripheral Neuropathy.

Seminars in neurology
2024

Bilateral Neuralgic Amyotrophy with Multiple Cranial Nerve Involvement and Deep Vein Thrombosis in a Known Case of Celiac Disease.

Neurology India
2024

Spectrum of Clinical Variability with SEPT9 Gene Mutation in Hereditary Neuralgic Amyotrophy: Understanding the Pathogenesis Using Molecular Dynamics Simulation Study.

Neurology India
2024

Neuralgic amyotrophy presentation of acute intermittent porphyria: A case report.

Journal of the peripheral nervous system : JPNS
2025

Neuralgic amyotrophy: An update in evaluation, diagnosis, and treatment approaches.

Muscle &amp; nerve
2024

Neurobartonelloses: emerging from obscurity!

Parasites &amp; vectors
2024

Immune triggers preceding neuralgic amyotrophy.

European journal of neurology
2024

Phrenic neuropathy: A different flavor of the same dish.

Muscle &amp; nerve
2025

Neuralgic amyotrophy of Parsonage and Turner. Which nerves are most frequently involved in daily practice? Data from 355 patients.

Joint bone spine
2024

Single center experience with hourglass-like constriction neuropathy of suprascapular nerve.

Muscle &amp; nerve
2024

Serological indication of chronic inflammatory demyelinating polyneuropathy as an extrahepatic manifestation of hepatitis E virus infection.

Scientific reports
2024

Parsonage-Turner Syndrome and SARS-CoV-2 Infection: A Literature Review With Case Presentation.

Cureus
2024

Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study.

The Lancet. Neurology
2024

Ways to think about vasculitic neuropathy.

Current opinion in neurology
2024

Neurolysis of the Long Thoracic Nerve for Scapular Winging due to Isolated Serratus Anterior Palsy: Early and Midterm Results in 29 Patients.

Journal of hand and microsurgery
2024

A case report of neuralgic amyotrophy.

Frontiers in neurology
2024

Parsonage-Turner syndrome, affecting suprascapular nerve and especially to infraspinatus muscles after COVID-19 vaccination in a professional wrestler, a case report and literature review of causes and treatments.

BMC neurology
2024

Bilateral Phrenic Nerve Palsy Associated With Neuralgic Amyotrophy.

Cureus
2024

Focal inflammatory neuropathies.

Handbook of clinical neurology
2024

The role of imaging in focal neuropathies.

Handbook of clinical neurology
2024

Axillary and musculocutaneous neuropathies.

Handbook of clinical neurology
2024

Hepatitis E and diaphragmatic dysfunction: Case series and review of the literature.

Pneumologie (Stuttgart, Germany)
2024

Ultrasound accuracy for brachial plexus pathology.

Clinical radiology
2024

Parsonage-Turner Syndrome following COVID-19 Vaccination: A Systematic Review.

Vaccines
2024

COVID-19 Vaccine Related Cervical Radiculitis and Parsonage-Turner Syndrome: Case Report and Review of the Literature.

Turkish neurosurgery
2024

Electrodiagnostic studies and new diagnostic modalities for evaluation of peripheral nerve disorders.

Muscle &amp; nerve
2024

Neuralgic amyotrophy with multiple hourglass-like constrictions of anterior interosseous nerve: a case report.

Frontiers in neurology
2024

[Neuralgic amyotrophy: an inflammatory neuropathy and its surgical treatment].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V...
2024

Neuralgic Amyotrophy and Hourglass Nerve Constriction/Nerve Torsion: Two Sides of the Same Coin? A Clinical Review.

Brain sciences
2024

A patient with bilateral neuralgic amyotrophy and hepatitis E virus infection: an educational communication.

European journal of translational myology
2024

Multifocal recurrent neuralgic amyotrophy in an immunocompromised patient.

Journal of neurology
2024

Parsonage-Turner Syndrome and Hereditary Brachial Plexus Neuropathy.

Mayo Clinic proceedings
2024

Claw Hand in Parsonage Turner syndrome.

Journal of Brown hospital medicine
2024

[MR neurography reveals fascicular constriction of the median nerve in a patient with neuralgic amyotrophy].

Rinsho shinkeigaku = Clinical neurology
2023

Neuralgic amyotrophy with bilateral radial nerve torsion: A unique case and review of the literature.

Neurologia
2023

[Diagnostics and treatment of hourglass-like nerve constrictions and torsions in neuralgic amyotrophy].

Der Nervenarzt
2023

Neuralgic amyotrophy: sensitivity and specificity of magnetic resonance neurography in diagnosis: A retrospective study.

Medicine
2023

High-resolution MR neurography follow-up of SARS-CoV-2 vaccination-associated neuralgic amyotrophy.

Annals of clinical and translational neurology
2023

Application of a nerve stereoscopic reconstruction technique based on ultrasonic images in the diagnosis of neuralgic amyotrophy.

Frontiers in physiology
2023

Persistent Hourglass Constriction in Recovered Anterior Interosseous Nerve Palsy Due to Neuralgic Amyotrophy: A Case Report.

The journal of hand surgery Asian-Pacific volume
2024

Neurological manifestation of HEV infection: still a rare disease entity?

Journal of neurology
2023

[Neuralgic amyotrophy: a common cause of unilateral and bilateral diaphragmatic pareses].

Pneumologie (Stuttgart, Germany)
2024

Hourglass-like constrictions on MRI are common in electromyography-confirmed cases of neuralgic amyotrophy (Parsonage-Turner syndrome): A tertiary referral center experience.

Muscle &amp; nerve
2023

Hereditary Neuralgic Amyotrophy with a Lesion Distal to the Brachial Plexus on Magnetic Resonance Imaging.

Internal medicine (Tokyo, Japan)
2023

Autoimmune polyneuropathies.

Handbook of clinical neurology
2024

Neuropathies related to hepatitis E virus infection: A prospective, matched case-control study.

European journal of neurology
2023

Association of Parsonage-Turner syndrome with COVID-19 infection and vaccination: a systematic review.

The Journal of international medical research
2023

Long Thoracic Nerve Palsy: When Is Decompression Indicated.

Journal of hand surgery global online
2023

Clinical Spectrum of Postsurgical Parsonage-Turner Syndrome: A Perspective From an Electrodiagnostic Laboratory.

Cureus
2023

Increased 18 F-FDG uptake in denervated muscles in a case of Parsonage-Turner syndrome.

BMC neurology
2023

Patient with recurrent neuralgic amyotrophy; right brachial plexitis and left posterior interosseous neuropathy.

Ideggyogyaszati szemle
2023

Recurrent Neuralgic Amyotrophy With Bilateral Diaphragm Paralysis: A Case Report.

Archivos de bronconeumologia
2023

A frantic confusion: beyond rabies and anti-N-methyl-D-aspartate encephalitis.

Journal of neurovirology
2024

Hourglass-like constrictions of the radial nerve in the neuralgic amyotrophy: A case report.

Turkish journal of physical medicine and rehabilitation
2023

Winged Scapula: Clinical and Electrophysiological Features and Common Causes Based on 20 Years of Experience in a Referral Center in Turkey.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society
2023

Hepatitis E-associated neuralgic amyotrophy: a rare respiratory presentation.

British journal of hospital medicine (London, England : 2005)
2023

Clinical Outcomes of Upper Extremity Nerve Transfers in Neuralgic Amyotrophy.

Plastic and reconstructive surgery
2023

Parsonage-Turner Syndrome Following SARS-CoV-2 Infection: A Systematic Review.

Biomedicines
2023

WINGED SCAPULA CAUSED BY PARSONAGE-TURNER SYNDROME AFTER BNT162B2 MRNA COVID-19 VACCINATION.

European journal of case reports in internal medicine
2023

Needle electromyography abnormalities in the upper trapezius muscle in neuromuscular disorders.

Turkish journal of medical sciences
2023

Real-time quaking-induced conversion assays for prions: Applying a sensitive but imperfect test in clinical practice.

European journal of neurology
2023

A Rare Case of Neuralgic Amyotrophy Associated with Brucella Infection.

Infection and drug resistance
2023

[A 24-year-old female with acute onset shoulder pain].

Nederlands tijdschrift voor geneeskunde
2023

Effectiveness of an outpatient rehabilitation programme in patients with neuralgic amyotrophy and scapular dyskinesia: a randomised controlled trial.

Journal of neurology, neurosurgery, and psychiatry
2023

Neuralgic Amyotrophy After COVID-19 Vaccination in an Adolescent: Successful Intravenous Immunoglobulin Treatment.

Pediatric neurology
2023

Ultrasound Diagnostic and Physiotherapy Approach for a Patient with Parsonage-Turner Syndrome-A Case Report.

Sensors (Basel, Switzerland)
2023

Cerebral Adaptation Associated with Peripheral Nerve Recovery in Neuralgic Amyotrophy: A Randomized Controlled Trial.

Neurorehabilitation and neural repair
2023

The role of ultrasonography in diagnosis of neuralgic amyotrophy.

Skeletal radiology
2023

Parsonage-Turner syndrome following COVID-19 infection: a report of three cases.

JSES reviews, reports, and techniques
2022

Neuralgic Amyotrophy After ChAdOx1 nCoV-19 COVID-19 Vaccination.

Journal of clinical neuromuscular disease
2023

Targeted inactivation of the Septin2 and Septin9 genes in myelinating Schwann cells of mice.

Cytoskeleton (Hoboken, N.J.)
2023

Nerve Ultrasonography for the Diagnosis and Evaluation of Neuralgic Amyotrophy.

Internal medicine (Tokyo, Japan)
2022

Parsonage Turner syndrome after cervical trauma and COVID-19 infection: a case report and review of the literature.

AME case reports
2023

Neuralgic amyotrophy detected by magnetic resonance neurography: subclinical, bilateral, and multifocal brachial plexus involvement.

Neurological research
2022

Imaging of neuralgic amyotrophy in the acute phase.

Muscle &amp; nerve
2022

Associations of neuralgic amyotrophy with COVID-19 vaccination: Disproportionality analysis using the World Health Organization pharmacovigilance database.

Muscle &amp; nerve
2022

Diaphragmatic Dysfunction due to Neuralgic Amyotrophy After SARS-CoV-2 Vaccination: A Case Report.

Journal of Korean medical science
2022

An Uncommon Presentation of a Rare Syndrome: Parsonage-Turner Syndrome Presenting With C8 Root Involvement.

Cureus
2022

Parsonage-Turner Syndrome Following Covishield (AstraZeneca ChAdOx1 nCoV-19) Vaccination: A Case Report.

Cureus
2023

A standardized ultrasound approach in neuralgic amyotrophy.

Muscle &amp; nerve
2022

Parsonage-Turner Syndrome of Unclear Causation: A Case Report.

Cureus
2022

Phrenic nerve paralysis and phrenic nerve reconstruction surgery.

Handbook of clinical neurology
2022

"Nothing completely goes away". Dissociation between imaging and neurophysiology in the chronic phase after neuralgic amyotrophy.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
2022

[Bilateral Parsonage-Turner syndrome after COVID-19 vaccination. A case report and review of the literature].

Orvosi hetilap
2022

Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome.

Journal of clinical medicine
2022

[A case of neuralgic amyotrophy with extension disturbance of fingers after Cushing's syndrome remission].

Rinsho shinkeigaku = Clinical neurology
2022

Neuralgic amyotrophy in COVID-19 infection and after vaccination.

Annals of the Academy of Medicine, Singapore
2022

COVID-19 Vaccine-Induced Parsonage-Turner Syndrome: A Case Report and Literature Review.

Cureus
2022

Spinal Cord Stimulation as an approach to treating Parsonage Turner Syndrome.

Interventional pain medicine
2023

Parsonage-Turner Syndrome mimicking musculoskeletal shoulder pain: A case report during the SARS-CoV-2 pandemic era.

Journal of telemedicine and telecare
2022

Hepatitis E virus infects brain microvascular endothelial cells, crosses the blood-brain barrier, and invades the central nervous system.

Proceedings of the National Academy of Sciences of the United States of America
2022

Reachable workspace analysis is a potential measurement for impairment of the upper extremity in neuralgic amyotrophy.

Muscle &amp; nerve
2022

Neuralgic amyotrophy triggered by cytomegalovirus: to be aware of this clinical diagnosis.

Neurocase
2022

Neuralgic Amyotrophy with Concomitant Hereditary Neuropathy with Liability to Pressure Palsy as a Cause of Dropped Shoulder in a Child after Human Papillomavirus Vaccination: A Case Report.

Children (Basel, Switzerland)
2022

Shoulder palsy following SARS-CoV-2 infection: two cases of typical Parsonage-Turner syndrome.

European journal of neurology
2022

Perspectives of a patient and a physiatrist on neuralgic amyotrophy.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
2022

Bilateral neuralgic amyotrophy in a patient with livestock-associated hepatitis E virus infection.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
2022

Neuralgic amyotrophy associated with COVID-19 infection: the broken bough.

The Korean journal of pain
2022

Localized delivery of brain-derived neurotrophic factor from PLGA microspheres promotes peripheral nerve regeneration in rats.

Journal of orthopaedic surgery and research
2022

Isolated musculocutaneous involvement in neuralgic amyotrophy associated with SARS-CoV2 vaccination.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2022

Parsonage-Turner Syndrome following COVID-19 Infection: A Rare and Unique Case.

Advanced biomedical research
2022

Prevalence of Surgical Procedures at Symptomatic Onset of Prion Disease.

JAMA network open
2022

Recurrent brachial plexopathy as initial presentation of systemic lupus erythematosus: A case report and review of the literature.

Lupus
2022

Visuomotor processing is altered after peripheral nerve damage in neuralgic amyotrophy.

Brain communications
2022

Pearls & Oy-sters: Bilateral Mononeuropathic Neuralgic Amyotrophy Triggered by Bartonella henselae Infection Responsive to Immunoglobulin.

Neurology
2022

Parsonage-Turner syndrome and cytomegalovirus disease.

Clinical neuropathology
2022

COVID-19 and the peripheral nervous system. A 2-year review from the pandemic to the vaccine era.

Journal of the peripheral nervous system : JPNS
2021

Hepatitis E Virus Infection: Neurological Manifestations and Pathophysiology.

Pathogens (Basel, Switzerland)
2022

COVID-19: A putative trigger for neuralgic amyotrophy.

Revue neurologique
2021

Parsonage-Turner syndrome following coronavirus disease 2019 immunization with ChAdOx1-S vaccine: a case report and review of the literature.

Journal of medical case reports
2022

Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers.

Journal of cell science
2021

Leg paralysis after AstraZeneca COVID-19 vaccination diagnosed as neuralgic amyotrophy of the lumbosacral plexus: a case report.

The Journal of international medical research
2022

Diagnostic performance of diffusion-weighted MR neurography as an adjunct to conventional MRI for the assessment of brachial plexus pathology.

European radiology
2021

Hepatitis E Virus Quasispecies in Cerebrospinal Fluid with Neurological Manifestations.

Vaccines
2023

Neuralgic amyotrophy with isolated mononeuropathy of the musculocutaneous nerve: a problematic differential diagnosis of cervical radiculopathy.

Acta neurologica Belgica
2022

Variation of surgical anatomy of the thoracic portion of the long thoracic nerve.

Clinical anatomy (New York, N.Y.)
2021

Reporting of Acute Inflammatory Neuropathies with COVID-19 Vaccines: Subgroup Disproportionality Analyses in VigiBase.

Vaccines
2021

Posterior Interosseous Fascicular Constriction Within the Radial Nerve in a Diabetic Patient With Bilateral Neuralgic Amyotrophy: A Case Report.

Frontiers in neurology
2021

Parsonage-Turner Syndrome After SARS-CoV-2 BNT162b2 Vaccine: A Case Report.

JBJS case connector
2021

Ultrasound findings in hereditary neuralgic amyotrophy.

Muscle &amp; nerve
2021

Anterior interosseous nerve lession and distal myoclonus revealing a parsonage turner syndrome associated with hashimoto thyroiditys.

Radiology case reports
2021

Neuralgic Amyotrophy: Its Importance in Orthopedics Practice.

Spine surgery and related research
2021

Hepatitis E virus as a trigger for Guillain-Barré syndrome.

BMC neurology
2021

[Hepatits E virus can cause neurological disorders].

Ugeskrift for laeger
2021

Neuralgic amyotrophy following COVID-19 mRNA vaccination.

QJM : monthly journal of the Association of Physicians
2022

Anesthetic Management of a Patient With Bilateral Diaphragmatic Paralysis Secondary to Neuralgic Amyotrophy Undergoing Open Aortic Valve Replacement.

Journal of cardiothoracic and vascular anesthesia
2021

[Parsonage-Turner syndrome following severe SARS-CoV-2 infection].

Revue des maladies respiratoires
2021

A newly designed shoulder orthosis for patients with glenohumeral subluxation: a clinical evaluation study.

Prosthetics and orthotics international
2021

Pregnancy-related Hand and Wrist Problems.

The archives of bone and joint surgery
2021

Answer to Cabona et al « Isolated musculocutaneous nerve involvement in COVID-19 related Neuralgic amyotrophy» Joint Bone Spine 2021;88:105238 and to Finsterer and Scorza « SARS-CoV-2 or SARS-CoV-2 vaccination associated Parsonage-Turner syndrome». Joint Bone Spine 2021;88:105239.

Joint bone spine
2021

SARS-CoV-2 or SARS-CoV-2 vaccination associated Parsonage-Turner syndrome. Comment on: "Neuralgic amyotrophy and COVID-19 infection: 2 cases of spinal accessory nerve palsy" by Coll et al. Joint Bone Spine 2021;88:105196.

Joint bone spine
2021

Bilateral diaphragmatic paralysis and Lyme neuroborreliosis. Ten years of follow-up.

Medicina
2021

Isolated musculocutaneous nerve involvement in COVID-19 related Neuralgic amyotrophy. Comment on: "Neuralgic amyotrophy and COVID-19 infection: 2 cases of spinal accessory nerve palsy" by Coll et al. Joint Bone Spine 2021;88:105196.

Joint bone spine
2021

Neuralgic Amyotrophy as the First Presentation of Lymphoma.

Internal medicine (Tokyo, Japan)
2021

HEV-Associated Neuralgic Amyotrophy: A Multicentric Case Series.

Pathogens (Basel, Switzerland)
2021

Post-thoracotomy neuralgic amyotrophy in a patient with BAP1 tumor predisposition syndrome: Multimodality longitudinal follow-up.

Muscle &amp; nerve
2021

Neurological manifestations of hepatitis E virus infection: An overview.

World journal of gastroenterology
2021

Extended Neuralgic Amyotrophy Syndrome in a Confirmed COVID-19 Patient After Intensive Care Unit and Inpatient Rehabilitation Stay.

American journal of physical medicine &amp; rehabilitation
2021

Right hemidiaphragmatic paralysis after cervical transforaminal epidural steroid injection: illustrative case.

Journal of neurosurgery. Case lessons
2021

Hepatitis E: An update on One Health and clinical medicine.

Liver international : official journal of the International Association for the Study of the Liver
2021

A Parsonage-Turner Syndrome secondary to Parvovirus B19 infection.

Acta bio-medica : Atenei Parmensis
2021

Neuralgic amyotrophy and COVID-19 infection: 2 cases of spinal accessory nerve palsy.

Joint bone spine
2022

Painless idiopathic neuralgic amyotrophy after COVID-19 vaccination: A case report.

PM &amp; R : the journal of injury, function, and rehabilitation
2022

Neuralgic Amyotrophy of Posterior Interosseous Nerve: A Cryptic and Crucial Entity.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
2021

Off-Label Use of Intravenous Immunoglobulin with Methylprednisolone to Treat Parsonage-Turner Syndrome in a United States Marine.

Case reports in medicine
2021

Diaphragmatic paralysis resulting in respiratory failure as a feature of hepatitis E virus-associated neuralgic amyotrophy.

BMJ case reports
2021

Neuralgic amyotrophy: an underrecognized entity.

The Journal of international medical research
2021

Neuralgic amyotrophy associated with COVID-19 infection: a case report and review of the literature.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
2021

Scapular winging secondary to serratus anterior dysfunction: analysis of clinical presentations and etiology in a consecutive series of 96 patients.

Journal of shoulder and elbow surgery
Ver todos os 400 no EuropePMC

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Doenças relacionadas

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Referências e fontes

Bases de dados externas citadas neste artigo

Publicações científicas

Artigos indexados no PubMed ligados a esta doença no grafo RarasNet — título, periódico e PMID direto da fonte, sem intermediação de IA.

  1. Clinical characteristics and results after conservative treatment or interfascicular neurolysis of 58 limbs with spontaneous posterior interosseous nerve palsy: A prospective Japanese multicenter study.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association· 2026· PMID 41796461mais citado
  2. Clinical characteristics of hospitalized patients with hepatitis E virus infection in Poland: a multi-centre retrospective study.
    Advances in medical sciences· 2026· PMID 41748069mais citado
  3. Isolated phrenic neuropathy in neuralgic amyotrophy.
    Practical neurology· 2026· PMID 41760546mais citado
  4. Pre-Plexal Extension of Parsonage-Turner Syndrome With Nerve Root Involvement on Needle Electromyography.
    Journal of clinical neuromuscular disease· 2026· PMID 41766079mais citado
  5. Neuralgic amyotrophy: Incidence, specialty of diagnosing clinician, and delays in treatment.
    Hand surgery &amp; rehabilitation· 2026· PMID 41651220mais citado
  6. Clinical Features and Prognosis of SEPTIN9-Related Hereditary Neuralgic Amyotrophy.
    Eur J Neurol· 2026· PMID 41989263recente
  7. Physical Therapy Management of Scapular Dyskinesis Due to Spinal Accessory Nerve Palsy Secondary to Neuralgic Amyotrophy: A Case Report.
    Cureus· 2026· PMID 41960014recente
  8. Surgical treatment of hourglass-like nerve constrictions with allogeneic nerve: a series report of 4 cases.
    J Hand Microsurg· 2026· PMID 41908090recente
  9. A Rare Case of Neuralgic Amyotrophy Involving the Tibial Nerve Following Otologic Surgery.
    J Otol· 2026· PMID 41766846recente

Bases de dados e fontes oficiais

Identificadores e referências canônicas usadas para montar este verbete.

  1. ORPHA:2901(Orphanet)
  2. MONDO:0017362(MONDO)
  3. GARD:4228(GARD (NIH))
  4. Variantes catalogadas(ClinVar)
  5. Busca completa no PubMed(PubMed)
  6. Q17141939(Wikidata)

Dados compilados pelo RarasNet a partir de fontes abertas (Orphanet, OMIM, MONDO, PubMed/EuropePMC, ClinicalTrials.gov, DATASUS, PCDT/MS). Este conteúdo é informativo e não substitui avaliação médica.

Conteúdo mantido por Agente Raras · Médicos e pesquisadores podem colaborar

Amiotrofia neurálgica
Compêndio · Raras BR

Amiotrofia neurálgica

ORPHA:2901 · MONDO:0017362
Prevalência
1-5 / 10 000
Herança
Autosomal dominant, Not applicable
CID-10
G54.5 · Amiotrofia nevrálgica
CID-11
Início
Adult
Prevalência
0.0 (Europe)
MedGen
UMLS
C0221759
EuropePMC
Wikidata
Papers 10a
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